MCID: DMN026
MIFTS: 19

Dementia Pugilistica malady

Categories: Neuronal diseases, Rare diseases, Mental diseases

Aliases & Classifications for Dementia Pugilistica

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Sources:
31ICD10 via Orphanet, 54Orphanet
See all MalaCards sources

Aliases & Descriptions for Dementia Pugilistica:

Name: Dementia Pugilistica 54
Chronic Traumatic Encephalopathy 54
 
Punch-Drunk Syndrome 54
Boxer's Dementia 54

Classifications:



External Ids:

Orphanet54 ORPHA97353
ICD10 via Orphanet31 F01.8

Summaries for Dementia Pugilistica

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Wikipedia:71 Dementia pugilistica (DP) is a type of chronic traumatic encephalopathy (CTE), a neurodegenerative... more...

MalaCards based summary: Dementia Pugilistica, also known as chronic traumatic encephalopathy, is related to dementia and encephalopathy. Affiliated tissues include brain, cortex and temporal lobe.

Related Diseases for Dementia Pugilistica

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Diseases related to Dementia Pugilistica via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1dementia10.5
2encephalopathy10.3
3cerebritis10.1
4cerebral amyloid angiopathy9.9
5head injury9.9

Graphical network of diseases related to Dementia Pugilistica:



Diseases related to dementia pugilistica

Symptoms & Phenotypes for Dementia Pugilistica

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Drugs & Therapeutics for Dementia Pugilistica

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Drugs for Dementia Pugilistica (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Resveratrolexperimental, investigationalPhase 1112501-36-0, 955365-80-724856436, 445154
Synonyms:
(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol
(E)-5-(p-Hydroxystyryl)resorcinol
(E)-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
(E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol
(E)-resveratrol
 
3,4',5-Stilbenetriol
3,4',5-Trihydroxystilbene
3,4',5-trihydroxy-stilbene
MK-1775
trans-3,4',5 - Trihydroxystilbene
trans-3,4',5-trihydroxystilbene
trans-Resveratrol
2Peripheral Nervous System AgentsPhase 122776
3Platelet Aggregation InhibitorsPhase 12419
4Protective AgentsPhase 17190
5Antirheumatic AgentsPhase 110627
6AntioxidantsPhase 12928
7Analgesics, Non-NarcoticPhase 16260
8Anti-Inflammatory AgentsPhase 110355
9Anti-Inflammatory Agents, Non-SteroidalPhase 14295
10Antineoplastic Agents, PhytogenicPhase 15420
11AnalgesicsPhase 111287

Interventional clinical trials:

idNameStatusNCT IDPhase
1Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in BoxersCompletedNCT01321151Phase 1

Search NIH Clinical Center for Dementia Pugilistica

Genetic Tests for Dementia Pugilistica

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Anatomical Context for Dementia Pugilistica

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MalaCards organs/tissues related to Dementia Pugilistica:

36
Brain, Cortex, Temporal lobe

Publications for Dementia Pugilistica

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Articles related to Dementia Pugilistica:

(show all 19)
idTitleAuthorsYear
1
Dementia pugilistica: a severe tribute to a career. (25828776)
2015
2
Neurochemical profile of dementia pugilistica. (23268705)
2013
3
Frontal cortex neuropathology in dementia pugilistica. (22017610)
2012
4
Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages of Alzheimer's disease. (20102526)
2010
5
Dementia pugilistica with clinical features of Alzheimer's disease. (17952290)
2007
6
Dementia pugilistica. (17323762)
2006
7
Tau isoform profile and phosphorylation state in dementia pugilistica recapitulate Alzheimer's disease. (11484824)
2001
8
Neuropsychology of sports-related head injury: Dementia Pugilistica to Post Concussion Syndrome. (10949160)
1999
9
Dementia pugilistica and cavum septi pellucidi: born to box? (9421861)
1997
10
A laser microprobe mass analysis of brain aluminum and iron in dementia pugilistica: comparison with Alzheimer's disease. (9252800)
1997
11
Dementia pugilistica in an alcoholic achondroplastic dwarf. (8714284)
1996
12
Comparative investigation of neurofibrillary damage in the temporal lobe in Alzheimer's disease, Down's syndrome and dementia pugilistica. (8910904)
1996
13
Apolipoprotein E epsilon 4 and fatal cerebral amyloid angiopathy associated with dementia pugilistica. (7574475)
1995
14
Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases. (1285493)
1992
15
Neurofibrillary tangles in dementia pugilistica are ubiquitinated. (1850450)
1991
16
Neurofibrillary tangles in some cases of dementia pugilistica share antigens with amyloid beta-protein of Alzheimer's disease. (2407121)
1990
17
The cerebral vasculature in dementia pugilistica. (2732729)
1989
18
Immunocytochemistry of neurofibrillary tangles in dementia pugilistica and Alzheimer's disease: evidence for common genesis. (2904573)
1988
19
(Ex?) dementia pugilistica in ex-boxers. (5395420)
1969

Variations for Dementia Pugilistica

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Expression for genes affiliated with Dementia Pugilistica

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Search GEO for disease gene expression data for Dementia Pugilistica.

Pathways for genes affiliated with Dementia Pugilistica

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GO Terms for genes affiliated with Dementia Pugilistica

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Sources for Dementia Pugilistica

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet