MCID: DMN026
MIFTS: 20

Dementia Pugilistica malady

Neuronal diseases, Rare diseases, Mental diseases categories

Aliases & Classifications for Dementia Pugilistica

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Aliases & Descriptions for Dementia Pugilistica:

Name: Dementia Pugilistica 51
Chronic Traumatic Encephalopathy 51
 
Punch-Drunk Syndrome 51
Boxer's Dementia 51


Classifications:



External Ids:

Orphanet51 97353

Summaries for Dementia Pugilistica

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Wikipedia:68 Dementia pugilistica (DP) is a neurodegenerative disease with features of dementia that may affect... more...

MalaCards based summary: Dementia Pugilistica, also known as chronic traumatic encephalopathy, is related to dementia and encephalopathy. Affiliated tissues include brain, cortex and temporal lobe.

Related Diseases for Dementia Pugilistica

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Graphical network of the top 20 diseases related to Dementia Pugilistica:



Diseases related to dementia pugilistica

Symptoms for Dementia Pugilistica

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Drugs & Therapeutics for Dementia Pugilistica

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Drugs for Dementia Pugilistica (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Resveratrolexperimental, investigationalPhase 1101501-36-0, 955365-80-724856436, 445154
Synonyms:
(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol
(E)-5-(p-Hydroxystyryl)resorcinol
(E)-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
(E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol
(E)-resveratrol
 
3,4',5-Stilbenetriol
3,4',5-Trihydroxystilbene
3,4',5-trihydroxy-stilbene
MK-1775
trans-3,4',5 - Trihydroxystilbene
trans-3,4',5-trihydroxystilbene
trans-Resveratrol

Interventional clinical trials:

idNameStatusNCT IDPhase
1Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in BoxersCompletedNCT01321151Phase 1

Search NIH Clinical Center for Dementia Pugilistica

Genetic Tests for Dementia Pugilistica

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Anatomical Context for Dementia Pugilistica

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MalaCards organs/tissues related to Dementia Pugilistica:

33
Brain, Cortex, Temporal lobe

Animal Models for Dementia Pugilistica or affiliated genes

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Publications for Dementia Pugilistica

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Articles related to Dementia Pugilistica:

(show all 19)
idTitleAuthorsYear
1
Dementia pugilistica: a severe tribute to a career. (25828776)
2015
2
Neurochemical profile of dementia pugilistica. (23268705)
2013
3
Frontal cortex neuropathology in dementia pugilistica. (22017610)
2012
4
Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages of Alzheimer's disease. (20102526)
2010
5
Dementia pugilistica with clinical features of Alzheimer's disease. (17952290)
2007
6
Dementia pugilistica. (17323762)
2006
7
Tau isoform profile and phosphorylation state in dementia pugilistica recapitulate Alzheimer's disease. (11484824)
2001
8
Neuropsychology of sports-related head injury: Dementia Pugilistica to Post Concussion Syndrome. (10949160)
1999
9
Dementia pugilistica and cavum septi pellucidi: born to box? (9421861)
1997
10
A laser microprobe mass analysis of brain aluminum and iron in dementia pugilistica: comparison with Alzheimer's disease. (9252800)
1997
11
Comparative investigation of neurofibrillary damage in the temporal lobe in Alzheimer's disease, Down's syndrome and dementia pugilistica. (8910904)
1996
12
Dementia pugilistica in an alcoholic achondroplastic dwarf. (8714284)
1996
13
Apolipoprotein E epsilon 4 and fatal cerebral amyloid angiopathy associated with dementia pugilistica. (7574475)
1995
14
Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases. (1285493)
1992
15
Neurofibrillary tangles in dementia pugilistica are ubiquitinated. (1850450)
1991
16
Neurofibrillary tangles in some cases of dementia pugilistica share antigens with amyloid beta-protein of Alzheimer's disease. (2407121)
1990
17
The cerebral vasculature in dementia pugilistica. (2732729)
1989
18
Immunocytochemistry of neurofibrillary tangles in dementia pugilistica and Alzheimer's disease: evidence for common genesis. (2904573)
1988
19
(Ex?) dementia pugilistica in ex-boxers. (5395420)
1969

Variations for Dementia Pugilistica

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Expression for genes affiliated with Dementia Pugilistica

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Search GEO for disease gene expression data for Dementia Pugilistica.

Pathways for genes affiliated with Dementia Pugilistica

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GO Terms for genes affiliated with Dementia Pugilistica

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Sources for Dementia Pugilistica

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet