MCID: DMN026
MIFTS: 16

Dementia Pugilistica malady

Categories: Neuronal diseases, Rare diseases, Mental diseases

Aliases & Classifications for Dementia Pugilistica

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Aliases & Descriptions for Dementia Pugilistica:

Name: Dementia Pugilistica 52
Chronic Traumatic Encephalopathy 52
 
Punch-Drunk Syndrome 52
Boxer's Dementia 52

Classifications:



External Ids:

Orphanet52 ORPHA97353

Summaries for Dementia Pugilistica

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Wikipedia:69 Dementia pugilistica (DP) is a type of chronic traumatic encephalopathy (CTE), a neurodegenerative... more...

MalaCards based summary: Dementia Pugilistica, also known as chronic traumatic encephalopathy, is related to dementia and encephalopathy. Affiliated tissues include brain, cortex and temporal lobe.

Related Diseases for Dementia Pugilistica

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Diseases related to Dementia Pugilistica via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1dementia10.7
2encephalopathy10.4
3cerebritis10.3
4cerebral amyloid angiopathy10.0
5head injury10.0

Graphical network of diseases related to Dementia Pugilistica:



Diseases related to dementia pugilistica

Symptoms for Dementia Pugilistica

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Drugs & Therapeutics for Dementia Pugilistica

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Drugs for Dementia Pugilistica (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
ResveratrolPhase 1109501-36-0, 955365-80-724856436, 445154
Synonyms:
(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol
(E)-5-(p-Hydroxystyryl)resorcinol
(E)-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
(E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol
(E)-resveratrol
 
3,4',5-Stilbenetriol
3,4',5-Trihydroxystilbene
3,4',5-trihydroxy-stilbene
MK-1775
trans-3,4',5 - Trihydroxystilbene
trans-3,4',5-trihydroxystilbene
trans-Resveratrol

Interventional clinical trials:

idNameStatusNCT IDPhase
1Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in BoxersCompletedNCT01321151Phase 1

Search NIH Clinical Center for Dementia Pugilistica

Genetic Tests for Dementia Pugilistica

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Anatomical Context for Dementia Pugilistica

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MalaCards organs/tissues related to Dementia Pugilistica:

34
Brain, Cortex, Temporal lobe

Animal Models for Dementia Pugilistica or affiliated genes

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Publications for Dementia Pugilistica

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Articles related to Dementia Pugilistica:

(show all 19)
idTitleAuthorsYear
1
Dementia pugilistica: a severe tribute to a career. (25828776)
2015
2
Neurochemical profile of dementia pugilistica. (23268705)
2013
3
Frontal cortex neuropathology in dementia pugilistica. (22017610)
2012
4
Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages of Alzheimer's disease. (20102526)
2010
5
Dementia pugilistica with clinical features of Alzheimer's disease. (17952290)
2007
6
Dementia pugilistica. (17323762)
2006
7
Tau isoform profile and phosphorylation state in dementia pugilistica recapitulate Alzheimer's disease. (11484824)
2001
8
Neuropsychology of sports-related head injury: Dementia Pugilistica to Post Concussion Syndrome. (10949160)
1999
9
Dementia pugilistica and cavum septi pellucidi: born to box? (9421861)
1997
10
A laser microprobe mass analysis of brain aluminum and iron in dementia pugilistica: comparison with Alzheimer's disease. (9252800)
1997
11
Dementia pugilistica in an alcoholic achondroplastic dwarf. (8714284)
1996
12
Comparative investigation of neurofibrillary damage in the temporal lobe in Alzheimer's disease, Down's syndrome and dementia pugilistica. (8910904)
1996
13
Apolipoprotein E epsilon 4 and fatal cerebral amyloid angiopathy associated with dementia pugilistica. (7574475)
1995
14
Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases. (1285493)
1992
15
Neurofibrillary tangles in dementia pugilistica are ubiquitinated. (1850450)
1991
16
Neurofibrillary tangles in some cases of dementia pugilistica share antigens with amyloid beta-protein of Alzheimer's disease. (2407121)
1990
17
The cerebral vasculature in dementia pugilistica. (2732729)
1989
18
Immunocytochemistry of neurofibrillary tangles in dementia pugilistica and Alzheimer's disease: evidence for common genesis. (2904573)
1988
19
(Ex?) dementia pugilistica in ex-boxers. (5395420)
1969

Variations for Dementia Pugilistica

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Expression for genes affiliated with Dementia Pugilistica

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Search GEO for disease gene expression data for Dementia Pugilistica.

Pathways for genes affiliated with Dementia Pugilistica

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GO Terms for genes affiliated with Dementia Pugilistica

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Sources for Dementia Pugilistica

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet