MCID: DMN026
MIFTS: 19

Dementia Pugilistica

Categories: Neuronal diseases, Rare diseases, Mental diseases

Aliases & Classifications for Dementia Pugilistica

MalaCards integrated aliases for Dementia Pugilistica:

Name: Dementia Pugilistica 56
Chronic Traumatic Encephalopathy 56
Punch-Drunk Syndrome 56
Boxer's Dementia 56

Classifications:

Orphanet: 56  
Rare neurological diseases


External Ids:

Orphanet 56 ORPHA97353
ICD10 via Orphanet 34 F01.8

Summaries for Dementia Pugilistica

MalaCards based summary : Dementia Pugilistica, also known as chronic traumatic encephalopathy, is related to dementia and encephalopathy. The drugs Resveratrol and Analgesics have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and temporal lobe.

Wikipedia : 72 Dementia pugilistica (DP) is a type of chronic traumatic encephalopathy (CTE), a neurodegenerative... more...

Related Diseases for Dementia Pugilistica

Diseases related to Dementia Pugilistica via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 dementia 10.5
2 encephalopathy 10.3
3 cerebritis 10.1
4 cerebral amyloid angiopathy 9.9
5 head injury 9.9

Graphical network of the top 20 diseases related to Dementia Pugilistica:



Diseases related to Dementia Pugilistica

Symptoms & Phenotypes for Dementia Pugilistica

Drugs & Therapeutics for Dementia Pugilistica

Drugs for Dementia Pugilistica (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Resveratrol Experimental, Investigational Phase 1 501-36-0 445154
2 Analgesics Phase 1
3 Analgesics, Non-Narcotic Phase 1
4 Peripheral Nervous System Agents Phase 1
5 Platelet Aggregation Inhibitors Phase 1
6 Anti-Inflammatory Agents Phase 1
7 Anti-Inflammatory Agents, Non-Steroidal Phase 1
8 Protective Agents Phase 1
9 Antirheumatic Agents Phase 1
10 Antineoplastic Agents, Phytogenic Phase 1
11 Antioxidants Phase 1

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in Boxers Completed NCT01321151 Phase 1

Search NIH Clinical Center for Dementia Pugilistica

Genetic Tests for Dementia Pugilistica

Anatomical Context for Dementia Pugilistica

MalaCards organs/tissues related to Dementia Pugilistica:

39
Brain, Cortex, Temporal Lobe

Publications for Dementia Pugilistica

Articles related to Dementia Pugilistica:

(show all 19)
id Title Authors Year
1
Dementia pugilistica: a severe tribute to a career. ( 25828776 )
2015
2
Neurochemical profile of dementia pugilistica. ( 23268705 )
2013
3
Frontal cortex neuropathology in dementia pugilistica. ( 22017610 )
2012
4
Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages of Alzheimer's disease. ( 20102526 )
2010
5
Dementia pugilistica with clinical features of Alzheimer's disease. ( 17952290 )
2007
6
Dementia pugilistica. ( 17323762 )
2006
7
Tau isoform profile and phosphorylation state in dementia pugilistica recapitulate Alzheimer's disease. ( 11484824 )
2001
8
Neuropsychology of sports-related head injury: Dementia Pugilistica to Post Concussion Syndrome. ( 10949160 )
1999
9
Dementia pugilistica and cavum septi pellucidi: born to box? ( 9421861 )
1997
10
A laser microprobe mass analysis of brain aluminum and iron in dementia pugilistica: comparison with Alzheimer's disease. ( 9252800 )
1997
11
Comparative investigation of neurofibrillary damage in the temporal lobe in Alzheimer's disease, Down's syndrome and dementia pugilistica. ( 8910904 )
1996
12
Dementia pugilistica in an alcoholic achondroplastic dwarf. ( 8714284 )
1996
13
Apolipoprotein E epsilon 4 and fatal cerebral amyloid angiopathy associated with dementia pugilistica. ( 7574475 )
1995
14
Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases. ( 1285493 )
1992
15
Neurofibrillary tangles in dementia pugilistica are ubiquitinated. ( 1850450 )
1991
16
Neurofibrillary tangles in some cases of dementia pugilistica share antigens with amyloid beta-protein of Alzheimer's disease. ( 2407121 )
1990
17
The cerebral vasculature in dementia pugilistica. ( 2732729 )
1989
18
Immunocytochemistry of neurofibrillary tangles in dementia pugilistica and Alzheimer's disease: evidence for common genesis. ( 2904573 )
1988
19
(Ex?) dementia pugilistica in ex-boxers. ( 5395420 )
1969

Variations for Dementia Pugilistica

Expression for Dementia Pugilistica

Search GEO for disease gene expression data for Dementia Pugilistica.

Pathways for Dementia Pugilistica

GO Terms for Dementia Pugilistica

Sources for Dementia Pugilistica

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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