MCID: DMY001
MIFTS: 43

Demyelinating Polyneuropathy malady

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Demyelinating Polyneuropathy

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Aliases & Descriptions for Demyelinating Polyneuropathy:

Name: Demyelinating Polyneuropathy 11 13
 
Peripheral Demyelinating Neuropathy 11 67

Classifications:



External Ids:

Disease Ontology11 DOID:5214
SNOMED-CT61 23414001
NCIt44 C27062

Summaries for Demyelinating Polyneuropathy

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MalaCards based summary: Demyelinating Polyneuropathy, also known as peripheral demyelinating neuropathy, is related to myasthenia gravis and chronic lymphocytic leukemia. An important gene associated with Demyelinating Polyneuropathy is PMP22 (Peripheral Myelin Protein 22), and among its related pathways are L1CAM interactions and FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include t cells, spinal cord and brain, and related mouse phenotypes are behavior/neurological and nervous system.

Related Diseases for Demyelinating Polyneuropathy

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Diseases in the Demyelinating Polyneuropathy family:

Chronic Inflammatory Demyelinating Polyneuropathy Subacute Inflammatory Demyelinating Polyneuropathy

Diseases related to Demyelinating Polyneuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 169)
idRelated DiseaseScoreTop Affiliating Genes
1myasthenia gravis30.7CNTN2, FCGR2B
2chronic lymphocytic leukemia29.0AIF1, CNTN2, FCGR2B, HP, TTR
3chronic inflammatory demyelinating polyneuropathy12.5
4subacute inflammatory demyelinating polyneuropathy12.1
5pcwh syndrome11.9
6neuropathy, inflammatory demyelinating11.7
7guillain-barre syndrome11.4
8charcot-marie-tooth disease, type 2e11.1
9polyneuropathy11.1
10abnormal threshold of rods10.6PMP22, TTR
11lesion of sciatic nerve10.6PMP22, TTR
12chronic salpingitis10.5PMP22, TTR
13hypotrichosis 610.5PMP22, TTR
14transvestism10.5HP, TTR
15ovarian mucinous neoplasm10.4AIF1, TTR
16angiodysplasia10.4MAG, PMP22
17neuropathy10.4
18gastrointestinal allergy10.4CNTN1, NFASC
19artemis deficiency10.4CNTN1, NFASC
20hypervitaminosis d10.4APOA4, TTR
21mohr-tranebjaerg syndrome10.3MAG, PMP22
22secondary lacrimal atrophy10.3MAG, PMP22
23rheumatic disease10.2PTGDS, TTR
24infertility10.2FCGR2B, MAG, PMP22
25hepatitis10.1
26dystonia 410.1ALB, TTR
27hematocele of tunica vaginalis testis10.1ALB, TTR
28cartilage disease10.1ALB, TTR
29poems syndrome10.1
30alveolar periostitis10.1ALB, TTR
31speech and communication disorders10.0ALB, TTR
32chronic polyneuropathy10.0ALB, PMP22
33hemoglobin c disease10.0ALB, TTR
34vascular dementia10.0ALB, TTR
35constrictive pericarditis10.0ALB, TTR
36charcot-marie-tooth disease10.0
37hepatitis b10.0
38multifocal motor neuropathy10.0
39tooth disease10.0
40smooth muscle tumor10.0ALB, PMP22
41systemic lupus erythematosus9.9
42lymphoma9.9
43hepatitis c9.9
44lupus erythematosus9.9
45ovarian cystic teratoma9.9ALB, TTR
46hepatitis c virus9.9
47glomerulonephritis9.9
48leukemia9.9
49respiratory failure9.9
50cytomegalovirus infection9.9

Graphical network of the top 20 diseases related to Demyelinating Polyneuropathy:



Diseases related to demyelinating polyneuropathy

Symptoms for Demyelinating Polyneuropathy

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Drugs & Therapeutics for Demyelinating Polyneuropathy

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Drugs for Demyelinating Polyneuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 66)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
alemtuzumabapproved, investigationalPhase 4303216503-57-0
Synonyms:
Campath
 
MabCampath
alemtuzumab
2Rho(D) Immune GlobulinPhase 4, Phase 3, Phase 2317
3ImmunoglobulinsPhase 4, Phase 3, Phase 2, Phase 16045
4Immunoglobulins, IntravenousPhase 4, Phase 3, Phase 2324
5gamma-GlobulinsPhase 4, Phase 3, Phase 2317
6AntibodiesPhase 4, Phase 3, Phase 2, Phase 16045
7
Prednisoneapproved, vet_approvedPhase 3135953-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
8
rituximabapprovedPhase 3, Phase 21654174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
9
Mycophenolate mofetilapproved, investigationalPhase 3939128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
10
Mycophenolic acidapprovedPhase 393924280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
11
BenzocaineapprovedPhase 318921994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
12
Glycineapproved, nutraceutical, vet_approvedPhase 322656-40-6750
Synonyms:
(1-13c)glycinato
(15N)Glycine
15527_RIEDEL
15527_SIAL
15743-44-9 (mono-potassium salt)
17829-66-2 (cobalt salt)
18875-39-3
2,2-dialkylglycines
2-Aminoacetate
2-Aminoacetic acid
2311-65-1
25718-94-9
29728-27-6 (monoammonium salt)
32817-15-5 (copper salt)
33226_RIEDEL
33226_SIAL
33242-26-1 (calcium salt)
35947-07-0 (calcium salt (2:1))
410225_SIAL
50046_FLUKA
50046_SIGMA
513-29-1 (sulfate (3:1))
52955-63-2
56-40-6
57678-19-0
6000-43-7 (hydrochloride)
6000-44-8 (mono-hydrochloride salt)
63183-41-5 (hydrochloride hydrogen carbonate)
71295-98-2 (phosphate (1:1))
7490-95-1 (hydrochloride (2:1)
7490-95-1 (hydrochloride (2:1))
7575-55-5
848646-45-7
87867-94-5
AB-131/40217813
AB1002628
AC1L19XW
AC1Q28JW
AC1Q53O0
AI3-04085
AKOS000119626
AMINOACETIC ACID 1.5% IN PLASTIC CONTAINER
AR-1A0345
AR-1A0532
Acide aminoacetique
Acide aminoacetique [INN-French]
Acido aminoacetico
Acido aminoacetico [INN-Spanish]
Acidum aminoaceticum
Acidum aminoaceticum [INN-Latin]
Aciport
Amino-Acetate
Amino-Acetic acid
Aminoacetate
Aminoacetic acid
Aminoazijnzuur
Aminoessigsaeure
Aminoethanoate
Aminoethanoic acid
Amitone
B72BA06C-60E9-4A83-A24A-A2D7F465BB65
BPBio1_001222
Biomol-NT_000195
C00037
CCRIS 5915
CHEBI:15428
CHEBI:15705
CHEBI:16228
CHEMBL773
CID750
CPD-8569
Corilin
D00011
DB00145
EINECS 200-272-2
 
FEMA No. 3287
FT-0083159
G
G0099
G0317
G5417_SIGMA
G5523_SIGMA
G7126_SIGMA
G7403_SIGMA
G8790_SIGMA
G8898_SIGMA
GLY (IUPAC abbrev)
GLYCINE 1.5% IN PLASTIC CONTAINER
GLYCINE, ACS
Glicina
Glicina [INN-Spanish]
Glicoamin
Gly
Glycin
Glycine
Glycine (JP15/USP)
Glycine [INN]
Glycine iron sulphate (1:1)
Glycine, homopolymer (VAN)
Glycine, labeled with carbon-14
Glycine, non-medical
Glycine-UL-14C hydrochloride
Glycinum
Glycinum [INN-Latin]
Glycocoll
Glycolixir
Glycosthene
Glykokoll
Glyzin
Gyn-Hydralin
Gyn-hydralin
H-Gly-OH
H2N-CH2-COOH
HSDB 495
Hampshire glycine
Hgly
InChI=1/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5
KST-1A2919
KST-1A8102
L-Glycine
L-alpha-amino acids
L001246
LS-218
Leimzucker
MolPort-000-871-607
NCGC00024503-01
NCGC00024503-02
NChemBio.2007.13-comp1
NSC 25936
NSC25936
P8791_SIGMA
Padil
Polyglycine II
S04-0135
Sucre de gelatine
Tocris-0219
UNII-TE7660XO1C
W328707_ALDRICH
WLN: Z1VQ
aminoacetic acid
an alpha amino acid ester
bmse000089
gly
glycine
nchem.554-comp2
nchembio.121-comp9
nchembio.145-comp33
nchembio.198-comp12
nchembio.265-comp9
nchembio.266-comp30
polyglycine
13tannic acidapproved, NutraceuticalPhase 31892
14Immunosuppressive AgentsPhase 3, Phase 212770
15Bile Acids and SaltsPhase 3102
16Cholic AcidsPhase 39
17Gastrointestinal AgentsPhase 38109
18Fingolimod HydrochloridePhase 387
19Liver ExtractsPhase 33868
20Antirheumatic AgentsPhase 3, Phase 210627
21Antineoplastic Agents, HormonalPhase 35407
22HormonesPhase 3, Phase 213979
23Hormone AntagonistsPhase 3, Phase 212778
24Anti-Inflammatory AgentsPhase 310355
25Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 3, Phase 212767
26Potassium Channel BlockersPhase 3, Phase 2176
273,4-diaminopyridinePhase 319
28Immunoglobulin GPhase 3265
29glucocorticoidsPhase 34920
30Pharmaceutical SolutionsPhase 3, Phase 27793
31Antibiotics, AntitubercularPhase 36972
32Anti-Bacterial AgentsPhase 310884
33
Interferon beta-1aapproved, investigationalPhase 2198145258-61-36438354
Synonyms:
145258-61-3
Avonex
Avonex (TN)
Belerofon
D04554
 
Fibroblast interferon
IFN-beta
Interferon beta precursor
Interferon beta-1a
Interferon beta-1a (USAN)
Interferon beta-1a (genetical recombination)
Interferon beta-1a (genetical recombination) (JAN)
34
4-AminopyridineapprovedPhase 268504-24-51727
Synonyms:
.gamma.-Aminopyridine
275875_ALDRICH
36687_FLUKA
36687_RIEDEL
4 AP
4 Aminopyridine
4 Aminopyridine Sustained Release
4-AP
4-Aminopyridine
4-Aminopyridine 10
4-Aminopyridine Sustained Release
4-Pyridinamine
4-Pyridylamine
4-aminopyridine
5-22-09-00106 (Beilstein Handbook Reference)
504-24-5
A 0152
A0414
A78403_ALDRICH
AB1004971
AC-907/25014071
AC1L1C3R
AC1Q52BM
AI3-52547
AKOS000119896
Amaya
Amino-4 pyridine
Amino-4-Pyridine
Ampydin
Ampyra
Avitrol
Avitrol 200
BB_SC-6974
BRN 0105782
BSPBio_001562
Bio1_000353
Bio1_000842
Bio1_001331
Bio2_000282
Bio2_000762
C13728
C5H6N2
CHEBI:34385
CHEMBL284348
CID1727
Caswell No. 038
Compound 1861
D015761
D04127
Dalfampridine
DivK1c_000572
EINECS 207-987-9
EL-970
EPA Pesticide Chemical Code 069201
EU-0100032
FT-0083754
Fampridina
Fampridine
Fampridine (USAN/INN)
Fampridine SR
Fampridine [USAN:INN]
Fampridine-PR
Fampridine-SR
Fampridinum
HC150041
HMS1361O04
HMS1791O04
HMS1921H15
HMS1989O04
HMS2092F05
HMS501M14
HSDB 6037
IDI1_000572
IDI1_034032
InChI=1/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7
KBio1_000572
 
KBio2_000282
KBio2_000635
KBio2_002850
KBio2_003203
KBio2_005418
KBio2_005771
KBio3_000563
KBio3_000564
KBio3_001888
KBioGR_000282
KBioGR_001505
KBioSS_000282
KBioSS_000635
LS-130202
Lopac-A-0152
Lopac0_000032
MLS000069400
Mi-W-3
MolPort-000-146-022
N07XX07
NCGC00015009-01
NCGC00015009-03
NCGC00015009-12
NCGC00024890-01
NCGC00024890-02
NCGC00024890-03
NCGC00024890-04
NCGC00024890-05
NCGC00024890-06
NCGC00024890-07
NCGC00024890-08
NCGC00024890-09
NCGC00024890-10
NINDS_000572
NSC 15041
NSC15041
Neurelan
Neurelan (TN)
P-Aminopyridine
PYRIDINE,4-AMINO
Philips 1861
Phillips 1861
Pimadin (free base)
Prc 1237
Pymadin
Pymadine
RCRA waste no. P008
SDCCGMLS-0066228.P001
SMR000058211
SPBio_001486
SPECTRUM1501130
STK298717
Spectrum2_001413
Spectrum3_000914
Spectrum4_001013
Spectrum5_001501
Spectrum_000155
Sustained Release, 4-Aminopyridine
TL8003344
Tocris-0940
UNII-BH3B64OKL9
UPCMLD-DP125
UPCMLD-DP125:001
VMI 10-3
VMI 103
VMI-10-3
VMI-103
VMI103
WLN: T6NJ DZ
[J.Pharmacol.Exp.Ther. 275:864 (1995)]
gamma-Aminopyridine
nchem.892-comp4
p-Aminopyridine
p-Aminopyridine [UN2671] [Poison]
p-Aminopyridine [UN2671] [Poison]
pyridin-4-amine
pyridin-4-ylamine
35
Folic Acidapproved, nutraceutical, vet_approvedPhase 2427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
36Complement System ProteinsPhase 2228
37Adjuvants, ImmunologicPhase 22484
38Antibodies, MonoclonalPhase 23795
39Anti-Infective AgentsPhase 221402
40Antiviral AgentsPhase 29732
41Interferon-betaPhase 2280
42AntioxidantsPhase 22928
43VitaminsPhase 25095
44interferonsPhase 22137
45MicronutrientsPhase 25802
46Protective AgentsPhase 27190
47Thioctic AcidPhase 2115
48Vitamin B ComplexPhase 24229
49Trace ElementsPhase 25802
50PlasminogenPhase 2236

Interventional clinical trials:

(show top 50)    (show all 70)
idNameStatusNCT IDPhase
1Alemtuzumab in Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIPD)Unknown statusNCT01757574Phase 4
2IVIg for Demyelination in Diabetes MellitusRecruitingNCT02372149Phase 4
3Phase III Clinical Trial of NPB-01 in Patients With Guillain-Barré SyndromeUnknown statusNCT02221271Phase 3
4Phase III Clinical Trial of NPB-01maintenance Therapy in Patients With Chronic Inflammatory Demyelinating Polyneuropathy.CompletedNCT01824251Phase 3
5Study of Efficacy and Safety of Privigen in Subjects With Chronic Inflammatory Demyelinating PolyneuropathyCompletedNCT01184846Phase 3
6Randomized Open-label Trial to Compare Efficacy and Tolerance of Corticosteroids and IVIgCompletedNCT01349270Phase 3
7Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) and Treatment With Subcutaneous Immunoglobulin (IgPro20)CompletedNCT01545076Phase 3
8Immune Globulin Intravenous (IGIV) For Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)CompletedNCT00220740Phase 3
9Phase III Randomized, Double-Blind, Placebo-Controlled Study of 3,4-Diaminopyridine for Demyelinating PolyneuropathyCompletedNCT00004939Phase 3
10Phase III Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Immune Globulin for Chronic Inflammatory Demyelinating PolyneuropathyCompletedNCT00004772Phase 3
11Phase III Multicenter Double Blind Controlled Trial of Human Immune Globulin Therapy in Previously Untreated Patients With Chronic Inflammatory Demyelinating NeuropathyCompletedNCT00004286Phase 3
12RIMAG Study: Trial of Rituximab Versus Placebo in Polyneuropathy Associated With Anti-MAG IgM Monoclonal GammopathyCompletedNCT00259974Phase 3
13Evaluate Efficacy and Safety of Fingolimod 0.5 mg Orally Once Daily Versus Placebo in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Patients.CompletedNCT01625182Phase 3
14Compassionate Treatment of Patients With Inborn Errors of Bile Acid Metabolism With Cholic AcidCompletedNCT00007020Phase 3
15Efficacy and Safety Study of GB-0998 for Guillain-Barré SyndromeCompletedNCT02342184Phase 3
16Phase III Efficacy, Safety, and Tolerability Study of HYQVIA/HyQvia and GAMMAGARD LIQUID/KIOVIG in CIDPRecruitingNCT02549170Phase 3
17Long-Term Tolerability and Safety of HYQVIA/HyQvia in CIDPRecruitingNCT02955355Phase 3
18Efficacy and Safety Study of I10E in Treatment of Patients With CIDPRecruitingNCT02293460Phase 3
19Efficacy and Safety Study of I10E in the Maintenance Treatment of Patients With CIDP: Extension of PRISM Study I10E-1302RecruitingNCT02317562Phase 3
20Extension Study of Maintenance Treatment With Subcutaneous Immunoglobulin (IgPro20) for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)Active, not recruitingNCT02027701Phase 3
21Interest of Mycophenolate for CIDP WeaningActive, not recruitingNCT02494505Phase 3
22Study to Evaluate Safety and Efficacy of Three Different Dosages of NewGam in Patients With Chronic Inflammatory Demyelinating Poly (Radiculo) NeuropathyNot yet recruitingNCT02638207Phase 3
23Safety and Efficacy Study of Three Different Dosages of NewGam in Patients With CIDPTerminatedNCT01225276Phase 2, Phase 3
24Inhibition of Complement Activation (Eculizumab) in Guillain-Barre Syndrome StudyUnknown statusNCT02029378Phase 2
25Lipoic Acid to Treat Chronic Inflammatory Demyelinating PolyneuropathyCompletedNCT00962429Phase 2
26Intravenous Immunoglobulin (IVIg) for the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)CompletedNCT00001287Phase 2
27Rituximab to Treat Neuropathy With Anti-MAG AntibodiesCompletedNCT00050245Phase 2
28Subcutaneous Immunoglobulin Treatment of Patients With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)CompletedNCT01017159Phase 2
29Safety and Efficacy of Avonex in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)CompletedNCT00099489Phase 2
30Assessment of Chronic Guillain-Barre Syndrome Improvement With Use of 4-aminopyridineCompletedNCT00056810Phase 2
31Early Mechanical Ventilation for Guillain Barré SyndromeCompletedNCT00167622Phase 2
32SERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot StudyRecruitingNCT02967679Phase 1, Phase 2
33Stem Cell Transplantation for Stiff Person Syndrome (SPS)RecruitingNCT02282514Phase 1, Phase 2
34Small Volume Plasma Exchange (SVPE) for Guillain-Barré Syndrome (GBS) PatientsRecruitingNCT02780570Phase 2
35Hematopoietic Stem Cell Transplantation in Chronic Inflammatory Demyelinating PolyneuropathyActive, not recruitingNCT00278629Phase 2
36Thrombolysis in Ischemic Spinal Cord StrokeActive, not recruitingNCT02242084Phase 2
37JET-GBS - Japanese Eculizumab Trial for GBSActive, not recruitingNCT02493725Phase 2
38High-dose Cyclophosphamide for Moderate to Severe Refractory Chronic Inflammatory Demyelinating PolyneuropathyWithdrawnNCT01236456Phase 2
39Pilot Study of Acthar® Gel in Chronic Inflammatory Demyelinating NeuropathyWithdrawnNCT02574962Phase 2
40Effects of an Intervention Program by Proprioceptive Neuromuscular Facilitation, in Muscle Force Irradiation.Unknown statusNCT02255708Phase 1
41Prevalence of Decreased Corneal Sensation in Patients With Chronic Inflammatory Demyelinating PolyneuropathyUnknown statusNCT01379833
42Safety Study of GBS Following Menactra Meningococcal VaccinationUnknown statusNCT00575653
43Perception and Multisensory Integration in Neurological Patients Using fMRIUnknown statusNCT01469858
44Change of Nerve Conduction Properties in IVIg Dependent NeuropathiesUnknown statusNCT01655394
45The Changes of Cytokines in Guillain Barré Syndrome: the Correlation With Clinical Manifestations and Skin InnervationUnknown statusNCT00173199
46Effect of Resistance and Aerobic Exercise in CIDP or MMNCompletedNCT02121678
47Immunoglobulin Dosage and Administration Form in CIDP and MMNCompletedNCT02111590
48Study of CIDP Patients During IVIG TreatmentCompletedNCT00305266
49MRI in Diagnosing and Monitoring CIDPCompletedNCT02017769
50Study of Electrical Impedance Myography (EIM) in ALSCompletedNCT02011204

Search NIH Clinical Center for Demyelinating Polyneuropathy

Genetic Tests for Demyelinating Polyneuropathy

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Anatomical Context for Demyelinating Polyneuropathy

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MalaCards organs/tissues related to Demyelinating Polyneuropathy:

35
T cells, Spinal cord, Brain, Skin, Liver, B cells, Endothelial

Animal Models for Demyelinating Polyneuropathy or affiliated genes

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MGI Mouse Phenotypes related to Demyelinating Polyneuropathy:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.0APOA4, CNTN1, CNTN2, FCGR2B, MAG, NFASC
2MP:00036317.7APOA4, CNTN1, CNTN2, FCGR2B, MAG, NFASC
3MP:00107687.1ALB, APOA4, CNTN1, FCGR2B, HP, NFASC
4MP:00053767.1ALB, APOA4, FCGR2B, HP, MAG, NFASC

Publications for Demyelinating Polyneuropathy

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Articles related to Demyelinating Polyneuropathy:

(show top 50)    (show all 658)
idTitleAuthorsYear
1
Paranodal dissection in chronic inflammatory demyelinating polyneuropathy with antineurofascin-155 and anticontactin-1 antibodies. (28073817)
2017
2
Poster 487 Chronic Inflammatory Demyelinating Polyneuropathy or Something Else?: A Case Report. (27673228)
2016
3
Loss of Schwann cell plasticity in chronic inflammatory demyelinating polyneuropathy (CIDP). (27677703)
2016
4
Genetic Creutzfeldt-Jakob disease mimicking chronic inflammatory demyelinating polyneuropathy. (26568971)
2015
5
Biomarkers of 'acute-onset' chronic inflammatory demyelinating polyneuropathy. (25183714)
2014
6
Distal acquired demyelinating symmetric polyneuropathy progressing to classic chronic inflammatory demyelinating polyneuropathy and response to fludarabine and cyclophosphamide. (23168526)
2013
7
Severe hyponatremia as the initial sign preceding guillain-barrAc syndrome, an acute inflammatory demyelinating polyneuropathy: a case report. (23476842)
2013
8
Chronic inflammatory demyelinating polyneuropathy. (23642722)
2013
9
The diagnosis of chronic inflammatory demyelinating polyneuropathy: a Delphi-method approach. (24052115)
2013
10
Immunoglobulin G level variations in treated chronic inflammatory demyelinating polyneuropathy: clues for future treatment regimens? (23645220)
2013
11
Subacute inflammatory demyelinating polyneuropathy disclosed by massive nerve root enhancement in CMT1A. (22173780)
2012
12
Diagnostic and therapeutic challenges in chronic inflammatory demyelinating polyneuropathy and other immune-mediated neuropathies. (21157311)
2011
13
Acute clinical onset chronic inflammatory demyelinating polyneuropathy in a dog. (21996805)
2011
14
Differential gene expression in chronic inflammatory demyelinating polyneuropathy (CIDP) skin biopsies. (19922956)
2010
15
Chronic inflammatory demyelinating polyneuropathy disease activity status: recommendations for clinical research standards and use in clinical practice. (21199104)
2010
16
Coincident chronic inflammatory demyelinating polyneuropathy and focal segmental glomerulosclerosis: a common autoimmunity? (20049621)
2010
17
Electrophysiology in chronic inflammatory demyelinating polyneuropathy with IGIV. (19260050)
2009
18
Post-influenza vaccine chronic inflammatory demyelinating polyneuropathy. (17993473)
2008
19
A distinct subgroup of chronic inflammatory demyelinating polyneuropathy with CNS demyelination and a favorable response to immunotherapy. (17306302)
2007
20
Chronic inflammatory demyelinating polyneuropathy associated with intestinal tuberculosis. (17712474)
2007
21
Diagnosis and treatment of chronic inflammatory demyelinating polyneuropathy. (16464406)
2006
22
Chronic idiopathic demyelinating polyneuropathy (CIDP) associated with Kaposi's sarcoma. (16794750)
2006
23
High-dose cyclophosphamide results in long-term disease remission with restoration of a normal quality of life in patients with severe refractory chronic inflammatory demyelinating polyneuropathy. (15703014)
2005
24
Chronic inflammatory demyelinating polyneuropathy in patients with systemic lupus erythematosus: prognosis and outcome. (16325658)
2005
25
The occurrence of carpal tunnel syndrome in chronic inflammatory demyelinating polyneuropathy. (16029960)
2005
26
Chronic Inflammatory Demyelinating Polyneuropathy. (12895398)
2003
27
Azathioprine hypersensitivity in a patient with peripheral demyelinating polyneuropathy. (12786856)
2003
28
Current concepts and controversy in chronic inflammatory demyelinating polyneuropathy. (12507413)
2003
29
Changes in serum macrophage-related factors in patients with chronic inflammatory demyelinating polyneuropathy caused by intravenous immunoglobulin therapy. (12639724)
2003
30
Chronic demyelinating polyneuropathy in graft-versus-host disease following allogeneic bone marrow transplantation. (12030409)
2002
31
Creutzfeldt-Jakob disease with amyotrophy and demyelinating polyneuropathy. (12433270)
2002
32
Successful autologous stem cell transplantation in a patient with chronic inflammatory demyelinating polyneuropathy. (11784845)
2002
33
Subarachnoid block for a patient with progressive chronic inflammatory demyelinating polyneuropathy. (11682419)
2001
34
Clinical and magnetic resonance imaging evidence of brain and spinal cord demyelination in a case of chronic inflammatory demyelinating polyneuropathy. (11437170)
2001
35
Visual evoked potentials study in chronic idiopathic inflammatory demyelinating polyneuropathy. (11090783)
2000
36
Treatment with interferon-alpha 2a in a patient with chronic inflammatory demyelinating polyneuropathy]. (10835937)
2000
37
Advances in chronic inflammatory demyelinating polyneuropathy: disease variants and inflammatory response mediators and modifiers. (10555828)
1999
38
Acute and chronic neuropathies: new aspects of Guillain-BarrAc syndrome and chronic inflammatory demyelinating polyneuropathy, an overview and an update. (9872432)
1998
39
Magnetic resonance imaging at the demyelinative foci in chronic inflammatory demyelinating polyneuropathy. (9109870)
1997
40
Chronic inflammatory demyelinating polyneuropathy (CIDP) in diabetics. (8902721)
1996
41
High-titer immunoglobulin M antibody to nerve-specific class III beta-tubulin in the serum of a patient with sensory demyelinating polyneuropathy. (8941286)
1996
42
Treatment of patients with chronic inflammatory demyelinating polyneuropathy. (8881435)
1996
43
Arthritis associated with circulating immune complexes following administration of intravenous immunoglobulin therapy in a patient with chronic inflammatory demyelinating polyneuropathy. (8926503)
1996
44
Mixed axonal-demyelinating polyneuropathy as predominant manifestation of myotonic dystrophy. (8196723)
1994
45
Magnetic resonance imaging of the cauda equina in chronic inflammatory demyelinating polyneuropathy. (8388677)
1993
46
Susceptibility to demyelinating polyneuropathy in plasma cell dyscrasia may be influenced by amino acid position 9 of the HLA-DR beta chain. (7681445)
1993
47
Chronic demyelinating polyneuropathy associated with eosinophilia-myalgia syndrome. (1534836)
1992
48
Chronic inflammatory demyelinating polyneuropathy in childhood: clinical and electrophysiological features. (1657385)
1991
49
CNS involvement in chronic inflammatory demyelinating polyneuropathy: an electrophysiological and MRI study. (1935761)
1991
50
Successful plasma exchange for a patient with chronic demyelinating polyneuropathy and cold agglutinin disease due to anti-Pra. (3009423)
1986

Variations for Demyelinating Polyneuropathy

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Expression for genes affiliated with Demyelinating Polyneuropathy

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Search GEO for disease gene expression data for Demyelinating Polyneuropathy.

Pathways for genes affiliated with Demyelinating Polyneuropathy

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Pathways related to Demyelinating Polyneuropathy according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.6CNTN1, CNTN2, NFASC
29.3ALB, TTR
39.3CNTN1, CNTN2, MAG, NFASC
49.1CNTN2, MAG, NFASC, NGF

GO Terms for genes affiliated with Demyelinating Polyneuropathy

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Cellular components related to Demyelinating Polyneuropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1paranode region of axonGO:003327010.5MAG, NFASC
2node of RanvierGO:003326810.2CNTN2, NFASC
3blood microparticleGO:00725628.6ALB, APOA4, HP
4myelin sheathGO:00432098.4ALB, CNTN1, CNTN2, MAG, NFASC
5extracellular regionGO:00055766.9ALB, APOA4, HP, NGF, PTGDS, TTR

Biological processes related to Demyelinating Polyneuropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1peripheral nervous system developmentGO:000742210.1NFASC, PMP22
2protein localization to juxtaparanode region of axonGO:007120510.0CNTN2, NFASC
3negative regulation of neuron projection developmentGO:001097710.0MAG, PMP22
4lipoprotein metabolic processGO:00421579.3ALB, APOA4

Molecular functions related to Demyelinating Polyneuropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1carbohydrate bindingGO:003024610.2CNTN1, CNTN2, MAG
2fatty acid bindingGO:00055049.9ALB, PTGDS
3antioxidant activityGO:00162099.3ALB, APOA4, HP
4protein bindingGO:00055155.0AIF1, ALB, APOA4, CNTN1, CNTN2, FCGR2B

Sources for Demyelinating Polyneuropathy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet