DHF
MCID: DNG002
MIFTS: 49

Dengue Hemorrhagic Fever (DHF) malady

Infectious diseases category

Summaries for Dengue Hemorrhagic Fever

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CDC:4 With more than one-third of the worldÔÇÖs population living in areas at risk for infection, dengue virus is a leading cause of illness and death in the tropics and subtropics. As many as 400 million people are infected yearly. Dengue is caused by any one of four related viruses transmitted by mosquitoes. There are not yet any vaccines to prevent infection with dengue virus and the most effective protective measures are those that avoid mosquito bites. When infected, early recognition and prompt supportive treatment can substantially lower the risk of medical complications and death.

MalaCards based summary: Dengue Hemorrhagic Fever, also known as DHF, is related to dengue disease and japanese encephalitis, and has symptoms including hemorrhagic lesions of the skin, thrombocytopenia and reduction in the fluid part of the blood. An important gene associated with Dengue Hemorrhagic Fever is LTA (lymphotoxin alpha), and among its related pathways are IL2 signaling events mediated by PI3K and IL4-mediated signaling events. The compounds okt3 and neopterin have been mentioned in the context of this disorder. Affiliated tissues include skin, endothelial and t cells.

Disease Ontology:9 A dengue disease that occurs when a person experiences a second infection with a heterologous dengue virus serotype, which is transmitted by aedes mosquito bite. the infection has symptom hemorrhagic lesions of the skin, has symptom thrombocytopenia, has symptom reduction in the fluid part of the blood, and has symptom high fever.

Aliases & Classifications for Dengue Hemorrhagic Fever

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Dengue Hemorrhagic Fever, Aliases & Descriptions:

Name: Dengue Hemorrhagic Fever 31 9 44 61
 
Dhf 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


External Ids:

Disease Ontology9 DOID:12206
MeSH34 D019595
NCIt39 C34683
ICD1026 A91

Related Diseases for Dengue Hemorrhagic Fever

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Graphical network of the top 20 diseases related to Dengue Hemorrhagic Fever:



Diseases related to dengue hemorrhagic fever

Symptoms for Dengue Hemorrhagic Fever

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Symptoms:

 9
  • hemorrhagic lesions of the skin
  • thrombocytopenia
  • reduction in the fluid part of the blood
  • high fever

Drugs & Therapeutics for Dengue Hemorrhagic Fever

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Drug clinical trials:

Search ClinicalTrials for Dengue Hemorrhagic Fever

Search NIH Clinical Center for Dengue Hemorrhagic Fever

Genetic Tests for Dengue Hemorrhagic Fever

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Anatomical Context for Dengue Hemorrhagic Fever

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MalaCards organs/tissues related to Dengue Hemorrhagic Fever:

32
Skin, Endothelial, T cells, Pituitary, Liver, Monocytes, Pancreas, Testes, Bone marrow, Bone, Whole blood, Kidney, B cells

Animal Models for Dengue Hemorrhagic Fever or affiliated genes

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Publications for Dengue Hemorrhagic Fever

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Articles related to Dengue Hemorrhagic Fever:

(show top 50)    (show all 453)
idTitleAuthorsYear
1
Hemostatic derangement in dengue hemorrhagic fever. (24120237)
2014
2
Role of cognitive parameters in dengue hemorrhagic fever and dengue shock syndrome. (24305068)
2013
3
Acute pancreatitis in dengue hemorrhagic fever. (22451187)
2012
4
Use of pentoxifylline in treatment of children with dengue hemorrhagic fever. (22481426)
2012
5
Persistent thrombocytopenia in dengue hemorrhagic fever. (21992910)
2011
6
Splenic rupture in dengue hemorrhagic fever: report of a case and review. (21788711)
2011
7
Dengue hemorrhagic fever: the sensitivity and specificity of the world health organization definition for identification of severe cases of dengue in Thailand, 1994-2005. (20205587)
2010
8
Clinical characteristics, risk factors, and outcomes in adults experiencing dengue hemorrhagic fever complicated with acute renal failure. (19346394)
2009
9
Dengue hemorrhagic fever complicated with encephalopathy and myocarditis: a case report. (19245163)
2008
10
Dengue and dengue hemorrhagic fever: management issues in an intensive care unit. (17530136)
2007
11
Difficulty in diagnosis and treatment of dengue hemorrhagic fever in patients with chronic renal failure: report of three cases of mortality. (17426183)
2007
12
T cell responses in dengue hemorrhagic fever: are cross-reactive T cells suboptimal? (16517753)
2006
13
Slower rates of clearance of viral load and virus-containing immune complexes in patients with dengue hemorrhagic fever. (16983615)
2006
14
Clinical features, complications and atypical manifestations of children with severe forms of dengue hemorrhagic fever in South India. (17090900)
2006
15
Economic impact of dengue fever/dengue hemorrhagic fever in Thailand at the family and population levels. (15964964)
2005
16
The emergence of epidemic dengue fever and dengue hemorrhagic fever in the Americas: a case of failed public health policy. (15969972)
2005
17
Association between sex, nutritional status, severity of dengue hemorrhagic fever, and immune status in infants with dengue hemorrhagic fever. (15827272)
2005
18
The correlation between coagulation test and albumin with antithrombin III in Dengue hemorrhagic fever. (15931699)
2004
19
Serious thrombocytopenia due to dengue hemorrhagic fever treated with high dosages of immunoglobulin. (12802766)
2003
20
Dengue and dengue hemorrhagic fever in the Americas: lessons and challenges. (12727523)
2003
21
Coagulation abnormalities in dengue hemorrhagic Fever: serial investigations in 167 Vietnamese children with Dengue shock syndrome. (12115093)
2002
22
Epidemiology of dengue in Sri Lanka before and after the emergence of epidemic dengue hemorrhagic fever. (12224589)
2002
23
The dengue and dengue hemorrhagic fever epidemic in Puerto Rico, 1994-1995. (11425166)
2001
24
The risk of dengue hemorrhagic fever (DHF) outbreak based on vector density in Kurau, Riau province, Indonesia. (11414442)
2000
25
A comparison of the pattern of liver involvement in dengue hemorrhagic fever with classic dengue fever. (11127322)
2000
26
Determining the incidence of dengue hemorrhagic fever in Puerto Rico. (10730299)
1999
27
A clinical study of the patients with dengue hemorrhagic fever during the epidemic of 1996 at Lucknow, India. (10928368)
1999
28
Early CD69 expression on peripheral blood lymphocytes from children with dengue hemorrhagic fever. (10515800)
1999
29
The 1996 outbreak of dengue hemorrhagic fever in Delhi, India. (10437946)
1998
30
Gallbladder wall thickening in dengue hemorrhagic fever: an ultrasonographic study. (7673451)
1995
31
Dengue virus and endothelial cell: a related phenomenon to thrombocytopenia and granulocytopenia in dengue hemorrhagic fever. (7886587)
1993
32
Emergence of epidemic dengue/dengue hemorrhagic fever as a public health problem in the Americas. (8012739)
1993
33
The first epidemic of dengue hemorrhagic fever in the People's Republic of China. (2042704)
1991
34
Dengue hemorrhagic fever in Cuba, 1981: a retrospective seroepidemiologic study. (2316788)
1990
35
International symposium on dengue and dengue hemorrhagic fever. Introduction. (1983048)
1990
36
Global epidemiology of dengue hemorrhagic fever. (2098928)
1990
37
Association of dengue hemorrhagic fever with the HLA system. (3498669)
1987
38
Dengue hemorrhagic fever--Puerto Rico. (3097497)
1986
39
Antibody-capture ELISA for detection of immunoglobulin M antibodies in sera from Japanese encephalitis and dengue hemorrhagic fever patients. (2989309)
1985
40
Atypical lymphocyte in dengue hemorrhagic fever: its value in diagnosis. (6740378)
1984
41
Surveillance of dengue hemorrhagic fever cases in Thailand. (7342320)
1981
42
Dengue hemorrhagic fever in Malaysia: the 1973 epidemic. (6105712)
1980
43
Early recognition of severe dengue hemorrhagic fever. (632709)
1978
44
Glomerular changes in dengue hemorrhagic fever. (786215)
1976
45
Immunofluorescent staining of the surfaces of lymphocytes in suspension from patients with dengue hemorrhagic fever. (61729)
1976
46
Dengue hemorrhagic fever: hospital reporting taken as an index of health education effectiveness. (140560)
1976
47
Indirect fluorescent antibody technic for demonstration of serum antibody in dengue hemorrhagic fever cases. (1099896)
1975
48
Detection of sporadic cases of dengue hemorrhagic fever. (5501443)
1970
49
Observations related to pathogenesis of dengue hemorrhagic fever. IV. Relation of disease severity to antibody response and virus recovered. (5419206)
1970
50
Observations related to pathogenesis of dengue hemorrhagic fever. V. Examination of agspecific sequential infection rates using a mathematical model. (5419207)
1970

Variations for Dengue Hemorrhagic Fever

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Expression for genes affiliated with Dengue Hemorrhagic Fever

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets, 31LifeMap Discovery®
See all sources
LifeMap Discovery
Genes differentially expressed in tissues of Dengue Hemorrhagic Fever patients vs. healthy controls: 31 (show all 400)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1CD38CD38 moleculeBlood+4.800.000
2IFI27interferon, alpha-inducible protein 27Blood+4.710.000
3RRM2ribonucleotide reductase M2Blood+4.630.000
4IGHMimmunoglobulin heavy constant muBlood+4.610.000
5BIRC5baculoviral IAP repeat containing 5Blood+4.470.000
6CAV1caveolin 1, caveolae protein, 22kDaBlood+4.410.000
7DLGAP5discs, large (Drosophila) homolog-associated protein 5Blood+4.310.000
8XISTX inactive specific transcript (non-protein coding)Blood-4.310.023
9CEP55centrosomal protein 55kDaBlood+4.280.000
10BUB1BUB1 mitotic checkpoint serine/threonine kinaseBlood+4.210.000
11SHCBP1SHC SH2-domain binding protein 1Blood+4.130.000
12PBKPDZ binding kinaseBlood+4.130.000
13IGKV3-20immunoglobulin kappa variable 3-20Blood+4.130.000
14TYMSthymidylate synthetaseBlood+4.070.000
15CDCA2cell division cycle associated 2Blood+4.060.000
16MKI67marker of proliferation Ki-67Blood+4.000.000
17CYAT1immunoglobulin lambda light chain-likeBlood+3.980.000
18MCM10minichromosome maintenance complex component 10Blood+3.980.000
19NOVnephroblastoma overexpressedBlood-3.970.000
20ZWINTZW10 interacting kinetochore proteinBlood+3.960.000
21CDK1cyclin-dependent kinase 1Blood+3.920.000
22HMMRhyaluronan-mediated motility receptor (RHAMM)Blood+3.900.000
23SDC1syndecan 1Blood+3.890.000
24SPC25SPC25, NDC80 kinetochore complex componentBlood+3.840.000
25NCAPGnon-SMC condensin I complex, subunit GBlood+3.840.000
26TK1thymidine kinase 1, solubleBlood+3.820.000
27CDC20cell division cycle 20Blood+3.800.000
28TNFRSF17tumor necrosis factor receptor superfamily, member 17Blood+3.800.000
29DTLdenticleless E3 ubiquitin protein ligase homolog (Drosophila)Blood+3.800.000
30TOP2Atopoisomerase (DNA) II alpha 170kDaBlood+3.800.000
31PI3peptidase inhibitor 3, skin-derivedBlood-3.760.000
32GLDCglycine dehydrogenase (decarboxylating)Blood+3.750.000
33IGLJ3immunoglobulin lambda joining 3Blood+3.750.000
34SESN3sestrin 3Blood-3.750.000
35KIF2Ckinesin family member 2CBlood+3.740.000
36CDT1chromatin licensing and DNA replication factor 1Blood+3.720.000
37CDKN3cyclin-dependent kinase inhibitor 3Blood+3.710.000
38KIAA0101KIAA0101Blood+3.710.000
39EIF1AYeukaryotic translation initiation factor 1A, Y-linkedBlood+3.710.034
40CNTNAP3contactin associated protein-like 3Blood-3.700.000
41CENPAcentromere protein ABlood+3.690.000
42TTKTTK protein kinaseBlood+3.670.000
43ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)Blood+3.660.000
44KIF11kinesin family member 11Blood+3.640.000
45IGLimmunoglobulin lambda locusBlood+3.640.000
46CCNB2cyclin B2Blood+3.610.000
47BUB1BBUB1 mitotic checkpoint serine/threonine kinase BBlood+3.600.000
48CDC6cell division cycle 6Blood+3.600.000
49SLC2A5solute carrier family 2 (facilitated glucose/fructose transporter), member 5Blood+3.600.000
50DUSP5dual specificity phosphatase 5Blood+3.600.000
51GGHgamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)Blood+3.570.000
52CCNA2cyclin A2Blood+3.560.000
53IGLV2-23immunoglobulin lambda variable 2-23Blood+3.550.000
54SELENBP1selenium binding protein 1Blood-3.550.000
55MELKmaternal embryonic leucine zipper kinaseBlood+3.540.000
56GINS2GINS complex subunit 2 (Psf2 homolog)Blood+3.530.000
57CHEK1checkpoint kinase 1Blood+3.510.000
58UHRF1ubiquitin-like with PHD and ring finger domains 1Blood+3.500.000
59E2F8E2F transcription factor 8Blood+3.490.000
60KDM5Dlysine (K)-specific demethylase 5DBlood+3.490.028
61RPS4Y1ribosomal protein S4, Y-linked 1Blood+3.480.048
62CCNB1cyclin B1Blood+3.450.000
63SEC61A1Sec61 alpha 1 subunit (S. cerevisiae)Blood+3.420.000
64CNTNAP3Bcontactin associated protein-like 3BBlood-3.410.000
65E2F7E2F transcription factor 7Blood+3.410.000
66HJURPHolliday junction recognition proteinBlood+3.400.000
67OR2W3olfactory receptor, family 2, subfamily W, member 3Blood-3.390.000
68IGLV1-44immunoglobulin lambda variable 1-44Blood+3.380.000
69NCOA3nuclear receptor coactivator 3Blood+3.370.000
70JAZF1JAZF zinc finger 1Blood-3.370.000
71KIF18Bkinesin family member 18BBlood+3.360.000
72ELL2elongation factor, RNA polymerase II, 2Blood+3.360.000
73SLC16A14solute carrier family 16, member 14Blood+3.350.001
74PDZK1IP1PDZK1 interacting protein 1Blood-3.330.001
75KIF20Akinesin family member 20ABlood+3.320.000
76TPX2TPX2, microtubule-associatedBlood+3.320.000
77ITM2Cintegral membrane protein 2CBlood+3.310.000
78UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)Blood+3.310.000
79TRIP13thyroid hormone receptor interactor 13Blood+3.300.000
80KIF15kinesin family member 15Blood+3.280.000
81AURKBaurora kinase BBlood+3.270.000
82KIF4Akinesin family member 4ABlood+3.260.000
83GTSE1G-2 and S-phase expressed 1Blood+3.260.000
84CDCA5cell division cycle associated 5Blood+3.250.000
85ESPL1extra spindle pole bodies homolog 1 (S. cerevisiae)Blood+3.240.000
86GINS1GINS complex subunit 1 (Psf1 homolog)Blood+3.230.000
87ANLNanillin, actin binding proteinBlood+3.230.000
88PKHD1L1polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1Blood+3.210.000
89RAD51AP1RAD51 associated protein 1Blood+3.200.000
90KLHL14kelch-like family member 14Blood+3.190.000
91CCND2cyclin D2Blood+3.170.000
92MANEAmannosidase, endo-alphaBlood+3.170.000
93DSC2desmocollin 2Blood-3.170.000
94ALDH1L2aldehyde dehydrogenase 1 family, member L2Blood+3.160.000
95SEC24ASEC24 family member ABlood+3.160.000
96FOXM1forkhead box M1Blood+3.150.000
97IGKV1D-13immunoglobulin kappa variable 1D-13Blood+3.150.000
98RAD51RAD51 recombinaseBlood+3.140.000
99IGLV4-60immunoglobulin lambda variable 4-60Blood+3.140.000
100OIP5Opa interacting protein 5Blood+3.130.000
101TUBB2Atubulin, beta 2A class IIaBlood-3.130.000
102IGF1insulin-like growth factor 1 (somatomedin C)Blood+3.130.000
103DERL3derlin 3Blood+3.120.000
104MBNL3muscleblind-like splicing regulator 3Blood-3.120.000
105DENND5BDENN/MADD domain containing 5BBlood+3.110.001
106KRT1keratin 1Blood-3.100.002
107MCM4minichromosome maintenance complex component 4Blood+3.100.000
108LAMC1laminin, gamma 1 (formerly LAMB2)Blood+3.090.000
109KCTD14potassium channel tetramerization domain containing 14Blood+3.090.000
110NUSAP1nucleolar and spindle associated protein 1Blood+3.080.000
111KIF14kinesin family member 14Blood+3.080.000
112C19orf10chromosome 19 open reading frame 10Blood+3.080.000
113SLC4A1solute carrier family 4 (anion exchanger), member 1 (Diego blood group)Blood-3.080.000
114MICAL2microtubule associated monooxygenase, calponin and LIM domain containing 2Blood-3.070.000
115NRG1neuregulin 1Blood-3.060.000
116TNS1tensin 1Blood-3.050.000
117SNCAsynuclein, alpha (non A4 component of amyloid precursor)Blood-3.020.000
118SEL1L3sel-1 suppressor of lin-12-like 3 (C. elegans)Blood+3.020.000
119IGLV6-57immunoglobulin lambda variable 6-57Blood+3.010.000
120DEPDC1DEP domain containing 1Blood+3.010.000
121IGLV3-19immunoglobulin lambda variable 3-19Blood+2.970.001
122CENPFcentromere protein F, 350/400kDaBlood+2.970.000
123SLC6A8solute carrier family 6 (neurotransmitter transporter), member 8Blood-2.970.000
124THBDthrombomodulinBlood-2.970.000
125SLC14A1solute carrier family 14 (urea transporter), member 1 (Kidd blood group)Blood-2.970.000
126UBE2Cubiquitin-conjugating enzyme E2CBlood+2.960.000
127B9D1B9 protein domain 1Blood+2.960.001
128EPT1ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)Blood+2.960.000
129POLE2polymerase (DNA directed), epsilon 2, accessory subunitBlood+2.950.000
130CENPUcentromere protein UBlood+2.950.000
131FCRL5Fc receptor-like 5Blood+2.940.000
132NEK2NIMA-related kinase 2Blood+2.930.000
133PLK4polo-like kinase 4Blood+2.930.000
134TROAPtrophinin associated proteinBlood+2.920.000
135HRASLS2HRAS-like suppressor 2Blood+2.920.000
136DEPDC1BDEP domain containing 1BBlood+2.910.000
137FKBP11FK506 binding protein 11, 19 kDaBlood+2.910.000
138NCAPHnon-SMC condensin I complex, subunit HBlood+2.910.000
139CDCA3cell division cycle associated 3Blood+2.910.000
140FAM210Bfamily with sequence similarity 210, member BBlood-2.910.000
141USP18ubiquitin specific peptidase 18Blood+2.900.000
142PPOXprotoporphyrinogen oxidaseBlood+2.900.000
143GAS6growth arrest-specific 6Blood+2.900.000
144SLC25A37solute carrier family 25 (mitochondrial iron transporter), member 37Blood-2.900.001
145SPATS2spermatogenesis associated, serine-rich 2Blood+2.890.000
146CASC5cancer susceptibility candidate 5Blood+2.880.000
147KCNN3potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3Blood+2.880.000
148HSP90B1heat shock protein 90kDa beta (Grp94), member 1Blood+2.870.001
149PTTG1pituitary tumor-transforming 1Blood+2.870.000
150PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)Blood-2.860.000
151KRT23keratin 23 (histone deacetylase inducible)Blood-2.860.000
152SPAG5sperm associated antigen 5Blood+2.860.000
153MAKmale germ cell-associated kinaseBlood-2.850.000
154FEN1flap structure-specific endonuclease 1Blood+2.840.000
155PARPBPPARP1 binding proteinBlood+2.840.000
156MYBL2v-myb avian myeloblastosis viral oncogene homolog-like 2Blood+2.830.000
157SLC38A10solute carrier family 38, member 10Blood+2.830.000
158CACNA2D3calcium channel, voltage-dependent, alpha 2/delta subunit 3Blood-2.830.000
159HSPA13heat shock protein 70kDa family, member 13Blood+2.830.000
160EMR3egf-like module containing, mucin-like, hormone receptor-like 3Blood-2.830.000
161NUF2NUF2, NDC80 kinetochore complex componentBlood+2.820.001
162GPRC5DG protein-coupled receptor, class C, group 5, member DBlood+2.800.003
163MLH3mutL homolog 3Blood-2.790.000
164STILSCL/TAL1 interrupting locusBlood+2.780.000
165CDC25Acell division cycle 25ABlood+2.780.000
166SKA1spindle and kinetochore associated complex subunit 1Blood+2.780.000
167TMOD1tropomodulin 1Blood-2.770.000
168KIAA1324KIAA1324Blood-2.770.000
169GPR146G protein-coupled receptor 146Blood-2.760.000
170CENPEcentromere protein E, 312kDaBlood+2.750.000
171CENPMcentromere protein MBlood+2.750.000
172HMGB3high mobility group box 3Blood+2.750.000
173GRAMD1CGRAM domain containing 1CBlood-2.730.000
174MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)Blood+2.730.001
175EAF2ELL associated factor 2Blood+2.710.000
176SPCS3signal peptidase complex subunit 3 homolog (S. cerevisiae)Blood+2.710.000
177SLC25A39solute carrier family 25, member 39Blood-2.710.000
178MYO1Dmyosin IDBlood+2.710.001
179PRC1protein regulator of cytokinesis 1Blood+2.710.000
180CENPWcentromere protein WBlood+2.700.000
181PRDX4peroxiredoxin 4Blood+2.700.000
182MTFR2mitochondrial fission regulator 2Blood+2.690.000
183SEC11CSEC11 homolog C (S. cerevisiae)Blood+2.690.000
184CADM1cell adhesion molecule 1Blood+2.680.000
185AURKAaurora kinase ABlood+2.670.001
186CHI3L1chitinase 3-like 1 (cartilage glycoprotein-39)Blood-2.670.000
187UBE2Tubiquitin-conjugating enzyme E2T (putative)Blood+2.670.000
188PDIA5protein disulfide isomerase family A, member 5Blood+2.660.000
189F2RL1coagulation factor II (thrombin) receptor-like 1Blood-2.660.000
190CEP128centrosomal protein 128kDaBlood+2.660.001
191SDF2L1stromal cell-derived factor 2-like 1Blood+2.660.000
192STRADBSTE20-related kinase adaptor betaBlood-2.660.000
193MCM2minichromosome maintenance complex component 2Blood+2.650.000
194OLIG1oligodendrocyte transcription factor 1Blood-2.650.000
195LOC730101uncharacterized LOC730101Blood+2.650.000
196ORC1origin recognition complex, subunit 1Blood+2.640.000
197CALUcalumeninBlood+2.620.003
198SLC1A4solute carrier family 1 (glutamate/neutral amino acid transporter), member 4Blood+2.620.000
199CDC45cell division cycle 45Blood+2.610.000
200TCP11L2t-complex 11, testis-specific-like 2Blood-2.610.000
201TSPAN5tetraspanin 5Blood-2.600.000
202TSHRthyroid stimulating hormone receptorBlood+2.600.003
203KIF23kinesin family member 23Blood+2.600.000
204SIGLEC17Psialic acid binding Ig-like lectin 17, pseudogeneBlood-2.600.000
205IGF2BP2insulin-like growth factor 2 mRNA binding protein 2Blood-2.600.000
206ABCC13ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogeneBlood-2.590.002
207C1QBcomplement component 1, q subcomponent, B chainBlood+2.590.001
208SNX5sorting nexin 5Blood+2.590.000
209PDIA4protein disulfide isomerase family A, member 4Blood+2.590.000
210ALPLalkaline phosphatase, liver/bone/kidneyBlood-2.590.000
211RFX2regulatory factor X, 2 (influences HLA class II expression)Blood-2.580.000
212PSAT1phosphoserine aminotransferase 1Blood+2.580.000
213KATNBL1katanin p80 subunit B-like 1Blood-2.580.000
214FANCIFanconi anemia, complementation group IBlood+2.580.000
215FABP5fatty acid binding protein 5 (psoriasis-associated)Blood+2.570.000
216TXLNG2Ptaxilin gamma 2, pseudogeneBlood+2.570.044
217EPB42erythrocyte membrane protein band 4.2Blood-2.560.004
218GLULglutamate-ammonia ligaseBlood-2.550.000
219DSCC1DNA replication and sister chromatid cohesion 1Blood+2.540.000
220CENPNcentromere protein NBlood+2.540.000
221FAM98Afamily with sequence similarity 98, member ABlood+2.540.000
222SLAMF7SLAM family member 7Blood+2.530.000
223CMTM2CKLF-like MARVEL transmembrane domain containing 2Blood-2.530.000
224IGKV4-1immunoglobulin kappa variable 4-1Blood+2.530.001
225SEPHS1selenophosphate synthetase 1Blood+2.530.000
226TMEM133transmembrane protein 133Blood+2.530.003
227HELLShelicase, lymphoid-specificBlood+2.530.001
228ARHGAP42Rho GTPase activating protein 42Blood+2.520.000
229METmet proto-oncogeneBlood+2.520.004
230GALNT2polypeptide N-acetylgalactosaminyltransferase 2Blood+2.510.000
231ALG14ALG14, UDP-N-acetylglucosaminyltransferase subunitBlood+2.510.001
232SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesinBlood+2.510.004
233CHAC2ChaC, cation transport regulator homolog 2 (E. coli)Blood+2.500.004
234GMNNgeminin, DNA replication inhibitorBlood+2.490.000
235HEY1hes-related family bHLH transcription factor with YRPW motif 1Blood-2.490.000
236TIGD3tigger transposable element derived 3Blood-2.480.000
237ANP32Eacidic (leucine-rich) nuclear phosphoprotein 32 family, member EBlood+2.470.000
238IL1RAPinterleukin 1 receptor accessory proteinBlood-2.470.000
239UBE2J1ubiquitin-conjugating enzyme E2, J1Blood+2.460.000
240IL1Binterleukin 1, betaBlood-2.460.005
241RGS16regulator of G-protein signaling 16Blood+2.450.000
242SLC45A4solute carrier family 45, member 4Blood-2.450.000
243CCNE2cyclin E2Blood+2.440.000
244TNFRSF10Ctumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domainBlood-2.440.000
245EZH2enhancer of zeste homolog 2 (Drosophila)Blood+2.440.000
246RAB30RAB30, member RAS oncogene familyBlood+2.440.001
247CCR10chemokine (C-C motif) receptor 10Blood+2.440.000
248NET1neuroepithelial cell transforming 1Blood+2.430.001
249TXNDC11thioredoxin domain containing 11Blood+2.430.000
250MND1meiotic nuclear divisions 1 homolog (S. cerevisiae)Blood+2.430.000
251TCF19transcription factor 19Blood+2.420.001
252COBLL1cordon-bleu WH2 repeat protein-like 1Blood+2.410.006
253ANKHANKH inorganic pyrophosphate transport regulatorBlood-2.410.000
254FCER1AFc fragment of IgE, high affinity I, receptor for; alpha polypeptideBlood-2.410.000
255TRAM2translocation associated membrane protein 2Blood+2.410.003
256CTLA4cytotoxic T-lymphocyte-associated protein 4Blood+2.400.000
257DCPSdecapping enzyme, scavengerBlood+2.400.000
258YBX3Y box binding protein 3Blood-2.400.000
259MAP7microtubule-associated protein 7Blood-2.390.000
260DHFRdihydrofolate reductaseBlood+2.390.000
261CASS4Cas scaffolding protein family member 4Blood-2.390.000
262HRASLSHRAS-like suppressorBlood-2.360.000
263ALAS2aminolevulinate, delta-, synthase 2Blood-2.340.002
264GGTA1Pglycoprotein, alpha-galactosyltransferase 1 pseudogeneBlood-2.340.000
265REPS2RALBP1 associated Eps domain containing 2Blood-2.330.000
266STX3syntaxin 3Blood-2.320.002
267IGF1Rinsulin-like growth factor 1 receptorBlood-2.320.000
268CCR3chemokine (C-C motif) receptor 3Blood-2.320.001
269DCAF12DDB1 and CUL4 associated factor 12Blood-2.310.000
270MAP3K7CLMAP3K7 C-terminal likeBlood-2.300.001
271SDC2syndecan 2Blood-2.290.000
272RUNDC3ARUN domain containing 3ABlood-2.290.010
273TSPAN2tetraspanin 2Blood-2.290.000
274WLSwntless Wnt ligand secretion mediatorBlood-2.290.000
275PIP4K2Aphosphatidylinositol-5-phosphate 4-kinase, type II, alphaBlood-2.280.000
276SMIM24small integral membrane protein 24Blood-2.270.002
277KCNJ2potassium inwardly-rectifying channel, subfamily J, member 2Blood-2.270.007
278HBBhemoglobin, betaBlood-2.270.002
279TRPM6transient receptor potential cation channel, subfamily M, member 6Blood-2.260.000
280HCAR3hydroxycarboxylic acid receptor 3Blood-2.250.013
281FOXO3forkhead box O3Blood-2.240.002
282UTS2urotensin 2Blood-2.240.019
283SLPIsecretory leukocyte peptidase inhibitorBlood-2.240.000
284R3HDM4R3H domain containing 4Blood-2.240.000
285RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1Blood-2.230.000
286TESCtescalcinBlood-2.230.001
287IL13RA1interleukin 13 receptor, alpha 1Blood-2.220.002
288ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3Blood-2.220.000
289DMTNdematin actin binding proteinBlood-2.220.001
290C19orf33chromosome 19 open reading frame 33Blood-2.200.002
291CPPED1calcineurin-like phosphoesterase domain containing 1Blood-2.200.000
292TREM1triggering receptor expressed on myeloid cells 1Blood-2.200.006
293PRSS33protease, serine, 33Blood-2.190.000
294MYL4myosin, light chain 4, alkali; atrial, embryonicBlood-2.190.003
295KAZNkazrin, periplakin interacting proteinBlood-2.190.000
296OSBP2oxysterol binding protein 2Blood-2.180.001
297BAG1BCL2-associated athanogeneBlood-2.180.000
298FAM212Bfamily with sequence similarity 212, member BBlood-2.180.000
299ITLN1intelectin 1 (galactofuranose binding)Blood-2.170.000
300CCNJLcyclin J-likeBlood-2.150.000
301TAL1T-cell acute lymphocytic leukemia 1Blood-2.150.003
302FCHO2FCH domain only 2Blood-2.140.000
303CREB5cAMP responsive element binding protein 5Blood-2.140.001
304HBQ1hemoglobin, theta 1Blood-2.140.029
305CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)Blood-2.130.000
306EMR2egf-like module containing, mucin-like, hormone receptor-like 2Blood-2.110.001
307NHSNance-Horan syndrome (congenital cataracts and dental anomalies)Blood-2.110.000
308NSUN7NOP2/Sun domain family, member 7Blood-2.100.001
309DGAT2diacylglycerol O-acyltransferase 2Blood-2.100.000
310ST6GALNAC2ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2Blood-2.100.001
311DPEP2dipeptidase 2Blood-2.100.000
312BEND2BEN domain containing 2Blood-2.090.001
313TMCC1transmembrane and coiled-coil domain family 1Blood-2.090.000
314KLF1Kruppel-like factor 1 (erythroid)Blood-2.090.010
315ST20suppressor of tumorigenicity 20Blood-2.090.003
316FBXO7F-box protein 7Blood-2.080.000
317NOGnogginBlood-2.080.003
318UBXN6UBX domain protein 6Blood-2.070.002
319RTN1reticulon 1Blood-2.070.000
320PTAFRplatelet-activating factor receptorBlood-2.070.001
321TGFAtransforming growth factor, alphaBlood-2.070.000
322ARHGEF12Rho guanine nucleotide exchange factor (GEF) 12Blood-2.060.004
323P2RY13purinergic receptor P2Y, G-protein coupled, 13Blood-2.060.001
324PRDM5PR domain containing 5Blood-2.040.026
325TMOD2tropomodulin 2 (neuronal)Blood-2.040.001
326MXI1MAX interactor 1, dimerization proteinBlood-2.030.003
327CR1Lcomplement component (3b/4b) receptor 1-likeBlood-2.030.015
328CD1CCD1c moleculeBlood-2.030.001
329HALhistidine ammonia-lyaseBlood-2.020.001
330HEMGNhemogenBlood-2.020.004
331MPZL3myelin protein zero-like 3Blood-2.010.000
332CXCL5chemokine (C-X-C motif) ligand 5Blood-2.010.024
333PID1phosphotyrosine interaction domain containing 1Blood-2.010.005
334AVILadvillinBlood-2.010.002
335IL1R1interleukin 1 receptor, type IBlood-2.000.004
336AOC3amine oxidase, copper containing 3Blood-2.000.000
337KIAA1211LKIAA1211-likeBlood-2.000.000
338CAMK1Dcalcium/calmodulin-dependent protein kinase IDBlood-2.000.000
339ADIPOR1adiponectin receptor 1Blood-2.000.000
340CYBRD1cytochrome b reductase 1Blood-2.000.000
341PTGDRprostaglandin D2 receptor (DP)Blood-2.000.001
342SORL1sortilin-related receptor, L(DLR class) A repeats containingBlood-2.000.000
343MBOAT2membrane bound O-acyltransferase domain containing 2Blood-1.990.001
344MRVI1murine retrovirus integration site 1 homologBlood-1.980.000
345EFHC2EF-hand domain (C-terminal) containing 2Blood-1.980.000
346MKRN1makorin ring finger protein 1Blood-1.980.001
347FLJ12120uncharacterized LOC388439Blood-1.980.038
348BTNL8butyrophilin-like 8Blood-1.980.020
349MMP25matrix metallopeptidase 25Blood-1.970.002
350FKBP1BFK506 binding protein 1B, 12.6 kDaBlood-1.970.002
351IL1R2interleukin 1 receptor, type IIBlood-1.970.011
352LYSTlysosomal trafficking regulatorBlood-1.970.000
353ASCC2activating signal cointegrator 1 complex subunit 2Blood-1.960.000
354ANK1ankyrin 1, erythrocyticBlood-1.960.009
355HBDhemoglobin, deltaBlood-1.960.039
356NPRL3nitrogen permease regulator-like 3 (S. cerevisiae)Blood-1.960.006
357C17orf103chromosome 17 open reading frame 103Blood-1.950.001
358CXCR1chemokine (C-X-C motif) receptor 1Blood-1.950.013
359CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)Blood-1.940.000
360LAMP2lysosomal-associated membrane protein 2Blood-1.930.001
361CDC42BPACDC42 binding protein kinase alpha (DMPK-like)Blood-1.930.002
362C12orf39chromosome 12 open reading frame 39Blood-1.930.018
363ALDH5A1aldehyde dehydrogenase 5 family, member A1Blood-1.930.002
364BLVRBbiliverdin reductase B (flavin reductase (NADPH))Blood-1.930.004
365MARCH8membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligaseBlood-1.930.001
366RXRAretinoid X receptor, alphaBlood-1.920.007
367SULF2sulfatase 2Blood-1.920.003
368LOC643072uncharacterized LOC643072Blood-1.920.006
369SEMA3Csema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3CBlood-1.920.000
370RAB11FIP1RAB11 family interacting protein 1 (class I)Blood-1.910.001
371KLC3kinesin light chain 3Blood-1.910.003
372ANGPT1angiopoietin 1Blood-1.910.000
373LOC284454uncharacterized LOC284454Blood-1.910.000
374MAP2K3mitogen-activated protein kinase kinase 3Blood-1.900.000
375FRMD4AFERM domain containing 4ABlood-1.900.005
376AOC2amine oxidase, copper containing 2 (retina-specific)Blood-1.890.000
377PLEK2pleckstrin 2Blood-1.880.009
378AMICA1adhesion molecule, interacts with CXADR antigen 1Blood-1.880.000
379GATA2GATA binding protein 2Blood-1.870.003
380TRIM58tripartite motif containing 58Blood-1.870.011
381CD1ECD1e moleculeBlood-1.870.004
382KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologBlood-1.870.000
383GYPCglycophorin C (Gerbich blood group)Blood-1.870.006
384AK1adenylate kinase 1Blood-1.860.002
385TTC25tetratricopeptide repeat domain 25Blood-1.860.005
386PBX1pre-B-cell leukemia homeobox 1Blood-1.860.006
387PINK1PTEN induced putative kinase 1Blood-1.850.000
388DOCK5dedicator of cytokinesis 5Blood-1.850.002
389SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1Blood-1.850.003
390FAM129Afamily with sequence similarity 129, member ABlood-1.850.000
391TM6SF1transmembrane 6 superfamily member 1Blood-1.850.000
392HAGHhydroxyacylglutathione hydrolaseBlood-1.850.004
393FRAT1frequently rearranged in advanced T-cell lymphomasBlood-1.850.001
394OGFRL1opioid growth factor receptor-like 1Blood-1.840.000
395HGDhomogentisate 1,2-dioxygenaseBlood-1.840.013
396PPM1Fprotein phosphatase, Mg2+/Mn2+ dependent, 1FBlood-1.840.000
397TBC1D22BTBC1 domain family, member 22BBlood-1.830.003
398RNF10ring finger protein 10Blood-1.830.002
399HCG27HLA complex group 27 (non-protein coding)Blood-1.820.006
400DPEP3dipeptidase 3Blood-1.820.000

Expression patterns in normal tissues for genes affiliated with Dengue Hemorrhagic Fever

Search GEO for disease gene expression data for Dengue Hemorrhagic Fever.

Pathways for genes affiliated with Dengue Hemorrhagic Fever

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Pathways related to Dengue Hemorrhagic Fever according to GeneCards/GeneDecks:

(show all 23)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
IL2 signaling events mediated by STAT537
9.9PTPN11, LTA
29.9CD40LG, LTA
39.2IFNA10, IFNA16, IFNA17
4
Show member pathways
8.9PTPN11, IFNA10, IFNA17, IFNA16
5
Show member pathways
8.9PTPN11, IFNA10, IFNA17, IFNA16
68.4IFNA17, IFNA16, IFNA10, IFNA13
78.4IFNA16, IFNA17, IFNA10, IFNA13
8
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
8.4IFNA16, IFNA17, IFNA13, IFNA10
98.4IFNA13, IFNA17, IFNA16, IFNA10
10
Show member pathways
8.4IFNA17, IFNA16, IFNA13, IFNA10
118.4IFNA10, IFNA13, IFNA16, IFNA17
128.1IFNA16, IFNA17, IFNA13, LTA, IFNA10
13
Show member pathways
8.1IFNA10, LTA, IFNA17, IFNA16, IFNA13
14
Show member pathways
8.1IFNA16, IFNA10, IFNA13, PTPN11, IFNA17
15
Show member pathways
Immune response CD16 signaling in NK cells59
8.1PTPN11, IFNA16, IFNA17, IFNA13, IFNA10
16
Show member pathways
7.8CD40LG, IFNA10, IFNA13, LTA, IFNA16, IFNA17
177.8IFNA13, IFNW1, IFNA10, IFNA17, IFNA16
18
Show member pathways
7.4IFNA17, IFNA16, LTA, IFNA13, IVNS1ABP, IFNA10
197.3IFNW1, IFNK, IFNA16, IFNA13, IFNA17, IFNA10
20
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways59
Immune response IL 1 signaling pathway59
7.0PTPN11, IFNA17, IFNK, IFNA10, IFNA13, IFNA16
21
Show member pathways
6.8IFNW1, IFNE, IFNA10, IFNA17, IFNA16, IFNA13
22
Show member pathways
Type III interferon signaling37
6.5PTPN11, IFNK, IFNA16, IFNA17, IFNA10, IFNE
23
Show member pathways
6.2CD40LG, IFNK, IFNA16, IFNA17, IFNA10, IFNE

Compounds for genes affiliated with Dengue Hemorrhagic Fever

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Compounds related to Dengue Hemorrhagic Fever according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1okt3449.9LTA, CD40LG
2neopterin449.9LTA, CD40LG
3mycophenolate mofetil44 50 1211.8LTA, CD40LG
4herbimycin a44 6010.7LTA, CD40LG, PTPN11
5rantes449.7LTA, CD40LG, PTPN11
6acetylcholine44 50 29 25 1213.6PTPN11, CD40LG, LTA
7ivig449.6LTA, CD40LG

GO Terms for genes affiliated with Dengue Hemorrhagic Fever

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Cellular components related to Dengue Hemorrhagic Fever according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055767.9IFNA13, IFNA10, IFNA17, IFNA16, IFNK
2extracellular spaceGO:0056155.9IFNA13, IFNW1, IFNE, IFNA10, IFNA17, IFNA16

Biological processes related to Dengue Hemorrhagic Fever according to GeneCards/GeneDecks:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1response to virusGO:0096158.3IVNS1ABP, IFNK, IFNA17, IFNW1
2regulation of type I interferon-mediated signaling pathwayGO:0603388.2IFNA13, IFNA10, PTPN11, IFNA17, IFNA16
3blood coagulationGO:0075968.1PTPN11, IFNA10, IFNA17, IFNA16, IFNA13
4type I interferon signaling pathwayGO:0603378.0IFNA16, PTPN11, IFNA13, IFNA10, IFNA17
5regulation of MHC class I biosynthetic processGO:0453437.1IFNA13, IFNW1, IFNE, IFNA10, IFNA17, IFNA16
6positive regulation of peptidyl-serine phosphorylation of STAT proteinGO:0331417.1IFNA13, IFNW1, IFNE, IFNA10, IFNA17, IFNA16
7response to exogenous dsRNAGO:0433307.1IFNA13, IFNW1, IFNE, IFNA10, IFNA17, IFNA16
8natural killer cell activation involved in immune responseGO:0023237.0IFNK, IFNA13, IFNW1, IFNE, IFNA10, IFNA17
9T cell activation involved in immune responseGO:0022867.0IFNA13, IFNW1, IFNA10, IFNK, IFNA16, IFNA17
10adaptive immune responseGO:0022507.0IFNK, IFNA16, IFNA17, IFNA10, IFNE, IFNW1
11defense response to virusGO:0516076.9IFNK, IFNA16, IFNA17, IFNE, IFNW1, IFNA13
12B cell proliferationGO:0421006.8CD40LG, IFNK, IFNA16, IFNA17, IFNA13, IFNE
13humoral immune responseGO:0069596.8IFNA13, IFNW1, IFNE, IFNA10, IFNA17, IFNA16
14B cell differentiationGO:0301836.8IFNA13, IFNW1, IFNE, IFNA10, IFNA17, IFNA16
15cytokine-mediated signaling pathwayGO:0192216.7PTPN11, IFNA10, IFNA17, IFNA13, IFNW1, IFNE
16innate immune responseGO:0450876.5IFNE, PTPN11, IFNA16, IFNW1, IFNA13, IFNA10

Molecular functions related to Dengue Hemorrhagic Fever according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:0051649.9LTA, CD40LG
2type I interferon receptor bindingGO:0051326.5IFNA13, IFNW1, IFNE, IFNA10, IFNA17, IFNA16
3cytokine activityGO:0051256.1LTA, IFNA13, IFNW1, IFNE, IFNA10, IFNA17

Products for genes affiliated with Dengue Hemorrhagic Fever

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  • Antibodies
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Sources for Dengue Hemorrhagic Fever

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet