MCID: DNT015
MIFTS: 61

Dent Disease malady

Categories: Genetic diseases, Rare diseases, Nephrological diseases

Aliases & Classifications for Dent Disease

About this section
Sources:
11Disease Ontology, 12diseasecard, 13DISEASES, 23GeneReviews, 24GeneTests, 25Genetics Home Reference, 26GTR, 30ICD10 via Orphanet, 36MedGen, 38MeSH, 39MESH via Orphanet, 44NCIt, 47NIH Rare Diseases, 49Novoseek, 51OMIM, 53Orphanet, 61SNOMED-CT, 63The Human Phenotype Ontology, 67UMLS, 68UMLS via Orphanet, 69UniProtKB/Swiss-Prot, 70Wikipedia
See all MalaCards sources

Aliases & Descriptions for Dent Disease:

Name: Dent Disease 51 11 23 47 24 25 53 12 49 38 13
Dent Disease 1 11 24 69 38 67
Dent's Disease 11 70 47 25 67
Dent Disease 2 11 38 67
Dents Disease 47 25 26
Low-Molecular-Weight Proteinuria with Hypercalciuria and Nephrocalcinosis 47 53
Renal Fanconi Syndrome with Nephrocalcinosis and Renal Stones 47 53
X-Linked Recessive Hypercalciuric Hypophosphatemic Rickets 47 53
X-Linked Recessive Nephrolithiasis 47 53
Dent Disease Type 1 53 26
 
Dent Syndrome 47 53
Nephrolithiasis-Hypercalciuria X-Linked Recessive 69
X-Linked Hypercalciuric Nephrolithiasis 24
X-Linked Hypercalciuric Urolithiasis 24
Clcn5-Related Dent Disease 24
Genetic Hypercalciuria 70
Nephrolithiasis Type 1 53
Nephrolithiasis 2 69
Nphl2 69

Characteristics:

Orphanet epidemiological data:

53
dent disease:
Inheritance: X-linked recessive; Age of onset: Childhood; Age of death: adult
dent disease type 1:
Inheritance: X-linked recessive; Age of onset: Childhood; Age of death: adult

HPO:

63
dent disease:
Inheritance: x-linked recessive inheritance
Onset and clinical course: phenotypic variability

Classifications:

Orphanet: 53 
Rare renal diseases


External Ids:

OMIM51 300009
Disease Ontology11 DOID:0050699
NCIt44 C123260
SNOMED-CT61 444645005
MESH via Orphanet39 C545036, D057973, C538212
UMLS via Orphanet68 C1839874, C0878681, C1848336
ICD10 via Orphanet30 N25.8
MedGen36 C1848336

Summaries for Dent Disease

About this section
NIH Rare Diseases:47 Dent disease is a chronic kidney disease that primarily affects males. While symptoms and severity vary, they usually begin in childhood and worsen over time. The most common feature of Dent disease is proteinuria (protein in the urine). Other common features include excess calcium in the urine (hypercalciuria); calcium deposits in the kidneys (nephrocalcinosis); and kidney stones. Less common features include rickets and mildy short stature. Progressive kidney problems often lead to kidney failure by early to mid-adulthood. There are two forms of Dent disease which are distinguished based on their genetic causes. Both forms are inherited in an X-linked recessive manner.Dent disease type 1 is caused by a mutation in the CLCN5 gene. Dent disease type 2 is caused by a mutation in the OCRL gene. Males with this form are also at increased risk for mild intellectual disability and hypotonia. Treatment is based on the symptoms present, aiming to delay progression of kidney disease and improve quality of life. Last updated: 9/20/2016

MalaCards based summary: Dent Disease, also known as dent disease 1, is related to hypophosphatemic rickets and dent disease 2, and has symptoms including Array, Array and Array. An important gene associated with Dent Disease is CLCN5 (Chloride Voltage-Gated Channel 5), and among its related pathways are 3-phosphoinositide degradation and Diuretics Pathway, Pharmacodynamics. Affiliated tissues include kidney, bone and breast, and related mouse phenotypes are homeostasis/metabolism and renal/urinary system.

Disease Ontology:11 A renal tubular transport disease that is characterized by tubular proteinuria, hypercalciuria, calcium nephrolithiasis, nephrocalcinosis and chronic kidney failure and has material basis in X-linked recessive inheritance of mutations in the CLCN5 gene or OCRL1 gene.

Genetics Home Reference:25 Dent disease is a chronic kidney disorder that occurs almost exclusively in males. In affected individuals, kidney problems result from damage to structures called proximal tubules. Signs and symptoms of this condition appear in early childhood and worsen over time.

OMIM:51 The term 'X-linked hypercalciuric nephrolithiasis' comprises several related forms of hereditary renal tubular... (300009) more...

UniProtKB/Swiss-Prot:69 Nephrolithiasis 2: An X-linked recessive renal disease belonging to the 'Dent disease complex', a group of disorders characterized by proximal renal tubular defect, hypercalciuria, nephrocalcinosis, and renal insufficiency. The spectrum of phenotypic features is remarkably similar in the various disorders, except for differences in the severity of bone deformities and renal impairment. Nephrolithiasis type 2 patients manifest hypercalciuria, hypophosphatemia, aminoaciduria, nephrocalcinosis and nephrolithiasis, renal insufficiency leading to renal failure in adulthood, rickets (33% of patients) and osteomalacia.

GeneReviews for NBK99494

Related Diseases for Dent Disease

About this section

Diseases in the Dent Disease family:

Dent Disease 2

Diseases related to Dent Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 30)
idRelated DiseaseScoreTop Affiliating Genes
1hypophosphatemic rickets26.4CLCN1, CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB
2dent disease 212.4
3nephrolithiasis, type i11.0
4proteinuria, low molecular weight, with hypercalciuric nephrocalcinosis11.0
5nystagmus 1, congenital, x-linked10.5CLCN5, OCRL
6bartter syndrome, type 4b, digenic10.4CLCNKA, CLCNKB
7silver-russell syndrome due to 7p11.2p13 microduplication10.4BGLAP, CLCN5
8amniotic band syndrome10.3CLCN5, OCRL
9bartter syndrome, type 4a10.3CLCNKA, CLCNKB
10acute inferoposterior infarction10.1CUBN, LRP2
11aromatase excess syndrome10.1BGLAP, LRP2
12familial mediterranean fever, ad10.1BGLAP, CLCN7
13microphthalmia10.1CLCN5, CUBN, LRP2, OCRL
14lowe syndrome10.0
15bone deterioration disease9.9BGLAP, CLCN7
16nephrolithiasis9.9
17early yaws9.9INPP5E, OCRL
18mild pre-eclampsia9.9BGLAP, CLCN5, CLDN16
19gestational diabetes9.9BGLAP, CLCNKA, SLC12A1
20glomerulosclerosis9.8
21central nervous system angiosarcoma9.8SLC12A1, SLC12A3
22vestibular neuronitis9.8CLCN5, CLDN16, OCRL, SLC12A1
23commensal bacterial infectious disease9.8BGLAP, CLCN5
24episodic kinesigenic dyskinesia 29.7CLCNKB, SLC12A1, SLC12A3
25cataract9.7
26nephrocalcinosis9.7
27star syndrome9.6CLCN5, INPP5E, LRP2, OCRL
28astrakhan spotted fever9.5CLCN5, CLCNKB, CLDN16, SLC12A3
29mucinous tubular and spindle renal cell carcinoma9.4CLCN5, CLCNKB, OCRL, SLC12A1, SLC12A3
30bestrophinopathy9.3CLCN5, CLCNKA, CLCNKB, SLC12A1, SLC12A3

Graphical network of the top 20 diseases related to Dent Disease:



Diseases related to dent disease

Symptoms for Dent Disease

About this section

Symptoms by clinical synopsis from OMIM:

300009

Clinical features from OMIM:

300009

Human phenotypes related to Dent Disease:

 53 63 (show all 46)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 renal insufficiency53 Very frequent (99-80%)
2 tubular atrophy53 Very frequent (99-80%)
3 proteinuria53 Very frequent (99-80%)
4 focal segmental glomerulosclerosis53 Very frequent (99-80%)
5 proximal tubulopathy63 53 Very frequent (99-80%) HP:0000114
6 renal phosphate wasting63 53 Very frequent (99-80%) HP:0000117
7 nephrocalcinosis63 53 Frequent (79-30%) HP:0000121
8 cataract53 Occasional (29-5%)
9 nephrolithiasis63 53 Very frequent (99-80%) HP:0000787
10 hematuria53 Very frequent (99-80%)
11 muscular hypotonia53 Occasional (29-5%)
12 intellectual disability, mild53 Occasional (29-5%)
13 abdominal pain53 Frequent (79-30%)
14 hypercalciuria63 53 Very frequent (99-80%) HP:0002150
15 bone pain63 53 Frequent (79-30%) HP:0002653
16 delayed epiphyseal ossification63 53 Occasional (29-5%) HP:0002663
17 rickets63 53 Occasional (29-5%) HP:0002748
18 recurrent fractures63 53 Very frequent (99-80%) HP:0002757
19 abnormality of the lower limb53 Occasional (29-5%)
20 osteomalacia63 53 Occasional (29-5%) HP:0002749
21 sparse bone trabeculae63 53 Occasional (29-5%) HP:0002752
22 thin bony cortex63 53 Occasional (29-5%) HP:0002753
23 aminoaciduria63 53 Very frequent (99-80%) HP:0003355
24 elevated serum creatine phosphokinase53 Frequent (79-30%)
25 bowing of the legs63 53 Occasional (29-5%) HP:0002979
26 bulging epiphyses63 53 Occasional (29-5%) HP:0003013
27 enlarged epiphyses53 Occasional (29-5%)
28 enlargement of the wrists63 53 Occasional (29-5%) HP:0003020
29 metaphyseal irregularity63 53 Occasional (29-5%) HP:0003025
30 enlargement of the ankles63 53 Occasional (29-5%) HP:0003029
31 glycosuria63 53 Very frequent (99-80%) HP:0003076
32 hyperphosphaturia63 53 Very frequent (99-80%) HP:0003109
33 low-molecular-weight proteinuria63 53 Very frequent (99-80%) HP:0003126
34 hyperuricosuria53 Very frequent (99-80%)
35 increased serum 1,25-dihydroxyvitamin d363 53 Very frequent (99-80%) HP:0003152
36 tubulointerstitial fibrosis53 Very frequent (99-80%)
37 non-acidotic proximal tubulopathy53 Very frequent (99-80%)
38 chronic kidney disease63 53 Very frequent (99-80%) HP:0012622
39 renal hypophosphatemia53 Very frequent (99-80%)
40 mild global developmental delay53 Occasional (29-5%)
41 hypophosphatemia63 HP:0002148
42 microscopic hematuria63 HP:0002907
43 femoral bowing63 HP:0002980
44 tibial bowing63 HP:0002982
45 short stature63 HP:0004322
46 fibular bowing63 HP:0010502

UMLS symptoms related to Dent Disease:


bone pain

Drugs & Therapeutics for Dent Disease

About this section

Drugs for Dent Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 223)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Methamphetamineapproved, illicitPhase 4232537-46-210836
Synonyms:
(+ )-Methylamphetamine
(+ )-methylamphetamine
(+)-(S)-Deoxyephedrine
(+)-(S)-N-alpha-Dimethylphenethylamine
(+)-(S)-N-alpha-dimethylphenethylamine
(+)-(S)-N-α-dimethylphenethylamine
(+)-(S)-deoxyephedrine
(+)-(s)-deoxyephedrine
(+)-(s)-n-alpha-dimethylphenethylamine
(+)-2-(N-Methylamino)-1-phenylpropane
(+)-Methylamphetamine
(+)-N,alpha-Dimethyl-beta-phenylethylamine
(+)-N,alpha-Dimethylphenethylamine
(+)-N,alpha-dimethyl-beta-phenylethylamine
(+)-N,alpha-dimethylphenethylamine
(+)-N-Methylamphetamine
(+)-N-methylamphetamine
(+)-methamphetamine
(+)-methylamphetamine
(+)-n,alpha-dimethyl-beta-phenylethylamine
(+)-n,alpha-dimethylphenethylamine
(+)-n-methylamphetamine
(2S)-N-methyl-1-phenylpropan-2-amine
(AlphaS)-N,alpha-dimethylbenzeneethanamine
(S)-(+)-Deoxyephedrine
(S)-(+)-Methamphetamine
(S)-(+)-N,alpha,dimethylphenethylamine
(S)-(+)-deoxyephedrine
(S)-(+)-methamphetamine
(S)-Methamphetamine
(S)-Methylamphetamine
(S)-N,alpha-Dimethylbenzeneethanamine
(S)-N,alpha-Dimethylbenzeneethanoamine
(S)-N,alpha-dimethylbenzeneethanamine
(S)-N,alpha-dimethylbenzeneethanoamine
(S)-N,α-dimethylbenzeneethanamine
(S)-methamphetamine
(S)-methylamphetamine
(alphaS)-N,alpha-dimethylbenzeneethanamine
(s)-(+)-deoxyephedrine
(s)-(+)-methamphetamine
(s)-(+)-n,alpha,dimethylphenethylamine
(s)-methamphetamine
(s)-methylamphetamine
(s)-n,alpha-dimethylbenzeneethanamine
(s)-n,alpha-dimethylbenzeneethanoamine
(αS)-N,α-dimethylbenzeneethanamine
1-Phenyl-2-methylamino-propan
1-Phenyl-2-methylamino-propan [German]
1-Phenyl-2-methylaminopropane
139-47-9
14611-50-8
1690-86-4
2S-(+)-Methamphetamine
45952-89-4
537-46-2
AC1L1W1Z
AC1Q4SVR
B40
Benzeneethanamine, N,alpha-dimethyl-, (S)- (9CI)
Benzeneethanamine, N,alpha-dimethyl-, (alphaS)- (9CI)
C07164
C10H15N
CHEBI:6809
CHEMBL1201201
CID10836
Crank
Crank [Street Name]
Crystal Meth
Crystal Meth [Street Name]
D-(S)-Methamphetamine
D-(s)-methamphetamine
D-1-Phenyl-2-methylaminopropan
D-1-Phenyl-2-methylaminopropan [German]
D-1-Phenyl-2-methylaminopropane
D-Deoxyephedrine
D-Desoxyephedrine
D-Methamphetamine
D-Methylamphetamine
D-N,alpha-Dimethylphenethylamine
D-N,alpha-dimethylphenethylamine
D-N-Methylamphetamine
D-Phenylisopropylmethylamine
D-deoxyephedrine
D-desoxyephedrine
D-methamphetamine
D-methylamphetamine
 
D-n,alpha-dimethylphenethylamine
D-n-methylamphetamine
D-phenylisopropylmethylamine
D08187
DB01577
DEA No. 1105
Desoxyephedrine hydrochloride
Desoxyn
Desyphed
Desyphed hydrochloride
Dextromethamphetamine
EINECS 208-668-7
HSDB 3359
ICE [Street Name]
Ice
L-Methamphetamine
L-methamphetamine
LS-103331
METHAMPHETAMINE
Metamfetamina
Metamfetamina [INN-Spanish]
Metamfetamina [inn-spanish]
Metamfetamine
Metamfetamine (INN)
Metamfetamine [INN]
Metamfetamine-m
Metamfetaminum
Metamfetaminum [INN-Latin]
Metamfetaminum [Latin]
Metamfetaminum [inn-latin]
Metamphetamine
Metanfetamina
Metanfetamina [INN-Spanish]
Metanfetamina [Spanish]
Metanfetamina [inn-spanish]
Meth
Meth (Street Name)
Methamphetamine
Methamphetamine, its salts, isomers, and salts of its isomers
Methamphetaminum
Methamphetaminum [INN-Latin]
Methamphetaminum [JP]
Methamphetaminum [inn-latin]
Methyl-.beta.-phenylisopropylamine
Methyl-beta-phenylisopropylamine
Methylamphetamine
MolPort-001-794-405
Métamfétamine
N-Methyl-1-phenyl-2-propanamine
N-Methyl-beta-phenylisopropylamin
N-Methyl-beta-phenylisopropylamin [German]
N-Methyl-beta-phenylisopropylamin [german]
N-Methyl-beta-phenylisopropylamine
N-Methylamphetamine
N-methyl-beta-phenylisopropylamin [german]
N-methyl-beta-phenylisopropylamine
N-methylamphetamine
NSC 25115
NSC25115
Norodin
PDSP1_001404
PDSP1_001405
PDSP2_001388
PDSP2_001389
Phenethylamine, N,alpha-dimethyl-, (S)-(+)- (8CI)
S-(+)-Methamphetamine
S-(+)-methamphetamine
Speed
Speed [Street Name]
Stimulex
UNII-44RAL3456C
WLN: 1MY1&1R -D
d-(S)-Methamphetamine
d-1-Phenyl-2-methylaminopropan [German]
d-1-phenyl-2-methylaminopropane
d-Deoxyephedrine
d-Desoxyephedrine
d-Methamphetamine
d-Methylamphetamine
d-N,.alpha.-Dimethylphenethylamine
d-N-Methylamphetamine
d-N-methylamphetamine
d-Phenylisopropylmethylamine
d-deoxyephedrine
d-desoxyephedrine
d-phenylisopropylmethylamine
desohyephedrine
methyl-β-phenylisopropylamine
2
TopiramateapprovedPhase 4, Phase 324797240-79-45284627
Synonyms:
-D-fructopyranose deriv.
.beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate (9CI)
2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
2,3:4,5-Bis-O-(1-methylethylidene) .beta.-D-fructopyranose sulfamate
2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate
2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
2,3:4,5-Di- O -isopropylidene-(beta)-D-fructopyranose sulfamate
2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose sulfamate
5H-Bis[1,3]dioxolo[4,5-b:4',5'-d]pyran, .beta.
97240-79-4
AKOS000424547
BIDD:GT0854
BIDD:PXR0127
BRN 5988957
BSPBio_002306
C052342
C07502
C12H21NO8S
CBChromo1_000352
CHEBI:129573
CHEMBL220492
CID5284627
CPD000466325
Cilag brand of topiramate
D00537
DB00273
Epitoma
Epitomax
HMS1922H06
HMS2051L09
HMS2093D20
HSDB 7531
Janssen brand of topiramate
KS-1122
KW-6485
LS-187392
LS-69764
MLS000759431
MLS001424070
McN 4853
McN-4853
MolPort-001-615-062
MolPort-002-885-869
NCGC00178714-01
 
Ortho brand of topiramate
RWJ 17021
RWJ-17021
RWJ-17021-000
S1438_Selleck
SAM001246601
SMR000466325
SPBio_000995
SPECTRUM1505801
STOCK1N-71037
Spectrum2_001128
T0575_SIGMA
TL8006021
TOR
TPM
Tipiramate
Tipiramate [French]
Tipiramato
Tipiramato [Spanish]
Topamac
Topamax
Topamax (TN)
Topamax Sprinkle
Topamax, Topiramate
Topimax
Topina
Topiramate
Topiramate (JAN/USAN/INN)
Topiramate (TPM)
Topiramate / Placebo
Topiramate [USAN:BAN:INN]
Topiramato
Topiramato [INN-Spanish]
Topiramatum
Topiramatum [INN-Latin]
Topiramic acid
Topomax
UNII-0H73WJJ391
USL-255
[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate
beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate
topiramate
topiramate tablet
topiramatum [Latin]
3
DopamineapprovedPhase 4, Phase 3375951-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
4
MetronidazoleapprovedPhase 4, Early Phase 1454443-48-14173
Synonyms:
1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole
1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole
1-(beta-Ethylol)-2-methyl-5-nitro-3-azapyrrole
1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole
1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole
1-(β-ethylol)-2-methyl-5-nitro-3-azapyrrole
1-(β-hydroxyethyl)-2-methyl-5-nitroimidazole
1-(β-oxyethyl)-2-methyl-5-nitroimidazole
1-Hydroxyethyl-2-methyl-5-nitroimidazole
2-(2-methyl-5-nitroimidazol-1-yl)ethanol
2-Methyl-5-nitro-1-imidazoleethanol
2-Methyl-5-nitroimidazole-1-ethanol
2-methyl-1-(2-hydroxyethyl)-5-nitroimidazole
2-methyl-3-(2-hydroxyethyl)-4-nitroimidazole
2-methyl-5-nitroimidazole-1-ethanol
443-48-1
46461_FLUKA
46461_RIEDEL
69198-10-3 (mono-hydrochloride)
99616-64-5
AB00052046
AC-10556
AC1L1HKS
AC1Q2P2Z
AKOS000269646
APMN
ARONIS24285
Acromona
Anagiardil
Apo-Metronidazole
Arilin
Atrivyl
BAS 02983617
BAY-5360
BCBcMAP01_000184
BIDD:GT0107
BPBio1_000004
BRD-K52020312-001-05-2
BRN 0611683
BSPBio_000002
BSPBio_002031
Bayer 5360
Bexon
Bio-0694
CAS-443-48-1
CB-01-14 MMX
CCRIS 410
CHEBI:39845
CHEBI:6909
CHEMBL137
CID4173
CONT
CPD000058175
Caswell No. 579AA
Clont
D00409
DB00916
Danizol
Deflamon
Deflamon-wirkstoff
DivK1c_000007
EINECS 207-136-1
EPA Pesticide Chemical Code 120401
Efloran
Elyzol
Entizol
Eumin
FLAGYL I.V. RTU IN PLASTIC CONTAINER
Flagemona
Flagesol
Flagil
Flagyl
Flagyl (TN)
Flagyl 375
Flagyl Er
Flagyl I.V.
Flagyl I.V. RTU
Flegyl
Florazole
Fossyol
Giatricol
Ginefla vir
Gineflavir
HMS1568A04
HMS1920N19
HMS2051G07
HMS2090B19
HMS2091F14
HMS500A09
HMS547C19
HSDB 3129
I14-0667
IDI1_000007
IDR-90105
KBio1_000007
KBio2_001515
KBio2_004083
KBio2_006651
KBio3_001531
KBioGR_000559
KBioSS_001515
Klion
Klont
LS-1264
M0924
M1547_SIGMA
M3761_FLUKA
M3761_SIGMA
M9036_SIGMA
METRO I.V
METRONIDAZOLE USP
MLS000028590
MLS000758286
Maybridge1_001999
Meronidal
Methronidazole
Methyl-5-nitroimidazole-1-ethanol
 
Metric
Metric 21
Metro Cream
Metro Gel
Metro I.V.
Metro I.V. In Plastic Container
MetroCream
MetroGel
MetroGel-Vaginal
MetroLotion
Metrodzhil
Metrogel-vaginal (TN)
Metrogyl
Metrolag
Metrolyl
Metromidol
Metronidaz
Metronidazol
Metronidazol [INN-Spanish]
Metronidazole (JP15/USP/INN)
Metronidazole Benzoate
Metronidazole Monohydrochloride
Metronidazole Phosphoester
Metronidazole [USAN:INN:BAN:JAN]
Metronidazole in Plastic Container
Metronidazolo
Metronidazolo [DCIT]
Metronidazolum
Metronidazolum [INN-Latin]
Metrotop
Metrozine
Metryl
Mexibol
Mexibol 'silanes'
MolPort-000-141-892
MolPort-002-502-101
Monagyl
Monasin
NCGC00016446-01
NCGC00016446-02
NCGC00022059-03
NCGC00022059-04
NCGC00022059-05
NCIOpen2_000337
NIDA
NINDS_000007
NSC 50364
NSC 69587
NSC-50364
NSC50364
NSC69587
Nalox
Nidagel
Noritate
Noritate (TN)
Novonidazol
Orvagil
Prestwick0_000081
Prestwick1_000081
Prestwick2_000081
Prestwick3_000081
Prestwick_334
Protostat
RP 8823
RP-8823
Rathimed
Rosased
S1907_Selleck
SAM001247010
SBB041018
SC 10295
SMP1_000189
SMR000058175
SPBio_000666
SPBio_001941
SPECTRUM1500412
STK177359
Sanatrichom
Satric
Spectrum2_000883
Spectrum3_000506
Spectrum4_000060
Spectrum5_001289
Spectrum_001035
Takimetol
Trichazol
Trichex
Tricho cordes
Tricho-gynaedron
Trichocide
Trichomol
Trichomonacid 'pharmachim'
Trichopal
Trichopol
Tricocet
Tricom
Tricowas B
Trikacide
Trikamon
Trikojol
Trikozol
Trimeks
Trivazol
UNII-140QMO216E
Vagilen
Vagimid
Vandazole
Vertisal
WLN: T5N CNJ A2Q B1 ENW
WLN: T5N CNJA2Q B1 ENW
WLN: T6NTJ DQ ANU1- ET5N CNJ A1 BNW
Wagitran
ZERO/004064
ZINC00113442
Zadstat
Zidoval
giniflavir
metronidazole
neo-Tric
5
Pregabalinapproved, illicit, investigationalPhase 4, Phase 3355148553-50-85486971
Synonyms:
(3S)-3-(aminomethyl)-5-methylhexanoic acid
(R-)-3-isobutyl GABA
(S)-3-(Aminomethyl)-5-methylhexanoic acid
(S)-3-Isobutyl gaba
(S+)-3-isobutyl GABA
121GE001
148553-50-8
3-Isobutyl gaba
3-isobutyl GABA
AC-1158
AC1NUP03
AKOS005145504
C080245
C8H17NO2
CHEBI:236161
CHEMBL1059
CI 1008
CI-1008
CID5486971
 
D02716
DB00230
FT-0080911
HSDB 7530
LS-75191
Lyrica
Lyrica (TN)
MolPort-000-861-733
PD 144723
PD-144723
Pregabalin
Pregabalin (JAN/USAN/INN)
Pregabalin [USAN]
Pregablin
S-(+)-3-isobutylgaba
S1731_Selleck
SBB062901
TL8001062
TOS-BB-0910
UNII-55JG375S6M
6
AcetylcholineapprovedPhase 477651-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
7
Amoxicillinapproved, vet_approvedPhase 444126787-78-033613, 2171
Synonyms:
(-)-6-(2-Amino-2-(P-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-(3.2.0)heptane-2-carboxylic acid
(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
26787-78-0
33911-69-2
34642-77-8 (mono-hydrochloride salt)
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-, D- (8CI)
6-(D-(-)-alpha-Amino-p-hydroxyphenylacetamido)penicillanic acid
6-(D-(-)-p-Hydroxy-alpha-aminobenzyl)penicillin
6-(P-Hydroxy-alpha-aminophenylacetamido)penicillanic acid
6-(a-Amino-4-hydroxyphenylacetamido)penicillanic acid
6-(p-Hydroxy-alpha-aminophenylacetamido)penicillanic acid
6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid
6-[[Amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 9CI
61336-70-7 (TRIHYDRATE)
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carbonyl
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid
71447-36-4
81030-75-3
AC-12263
AC1L1PY2
AMC
AMOXICILLIN CRYSTALLINE
AMOXICILLIN PEDIATRIC
AMPC
AUGMENTIN '125'
AUGMENTIN '200'
AUGMENTIN '250'
AUGMENTIN '400'
AUGMENTIN '500'
AUGMENTIN '875'
AUGMENTIN ES-600
AX
Actimoxi
Almodan
Ambap26787-78-0
Amix
Amoclen
Amolin
Amopen
Amopenixin
Amoram
Amox
Amox 250 Cap 250mg
Amox 500 Cap 500mg
Amox S 125 Sus 125mg/5ml
Amox S 250 Sus 250mg/5ml
Amoxi
Amoxi-Mast
Amoxi-mast
Amoxibiotic
Amoxicaps
Amoxicilina
Amoxicilina [INN-Spanish]
Amoxicillin (INN)
Amoxicillin (TN)
Amoxicillin (anhydrous)
Amoxicillin (inn)
Amoxicillin Trihydrate
Amoxicillin and clavulanate potassium
Amoxicillin anhydrous
Amoxicillin pediatric
Amoxicillin trihydrate
Amoxicillin(usan)
Amoxicilline
Amoxicilline [INN-French]
Amoxicilline [INN]
Amoxicilline [inn]
Amoxicillinum
Amoxicillinum [INN-Latin]
Amoxid
Amoxiden
Amoxil
Amoxivet
Amoxycillin
Amoxycillin Trihydrate
Amoxycillin trihydrate
Amoxycillin, BAN
Amoxymed
Amrit
Anemolin
Apo-Amoxi
Apo-Amoxi Cap 250mg
Apo-Amoxi Cap 500mg
Apo-Amoxi Pwr for Susp 125mg/5ml
Apo-Amoxi Pwr for Susp 250mg/5ml
Apo-amoxi
Apo-amoxi sugar free
Aspenil
BL-P 1410
BLP 1410
BPBio1_000499
BRD-K55044200-001-03-9
BRL 2333
BRL-2333
BSPBio_000453
 
Biomox
Bristamox
C06827
CHEBI:2676
CHEBI:53712
CHEMBL1082
CID33613
CPD000058707
Cemoxin
Clamoxyl
Clamoxyl (SKB)
D-(-)-alpha-Amino-p-hydroxybenzyl penicillin
D-(-)-alpha-Amino-p-hydroxybenzylpenicillin
D-(alpha-Amino-p-hydroxybenzyl)penicillin
D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid
D-Amoxicillin
D07452
DB01060
Delacillin
DisperMox
Dispermox
EINECS 248-003-8
Efpenix
Flemoxin
Galenamox
Gen-Amoxicillin 250mg
Gen-Amoxicillin 500mg
HMS1569G15
HSDB 3204
Hiconcil
Histocillin
Hydroxyampicillin
Ibiamox
Imacillin
LS-149721
Lamoxy
Larotid
MLS000028632
MLS002222248
Metafarma capsules
Metifarma capsules
MolPort-003-981-182
MolPort-005-933-687
Moxacin
Moxal
Moxatag
NCGC00179554-01
NSC 277174
NSC277174
Novamoxin Cap 250mg
Novamoxin Cap 500mg
Novamoxin Sus 125mg/5ml
Novamoxin Sus 250mg/5ml
Nu-Amoxi Cap 250mg
Nu-Amoxi Cap 500mg
Nu-Amoxi Sus 125/5ml
Nu-Amoxi Sus 250mg/5ml
Ospamox
P-Hydroxyampicillin
PHL-amoxicillin
PMS-amoxicillin
Pamoxicillin
Piramox
Polymox
Prestwick0_000357
Prestwick1_000357
Prestwick2_000357
Prestwick3_000357
Prestwick_713
Prevpac
Pro Amox Pwr for Oral Susp 125mg/5ml
Pro Amox-250 Cap 250mg
Pro Amox-500 Cap 500mg
Pro-Amox-250 Orl Sus 250mg/5ml
R-Hydroxyampicillin
Rimoxallin
Ro 10-8756
Robamox
SAM002264592
SMR000058707
SPBio_002374
Sauracillin
Sawamox PM
Sumox
Tolodina
Trimox
Unicillin
Utimox
Vetramox
Wymox
Zimox
alpha-Amino-p-hydroxybenzylpenicillin
alpha-amino-P-Hydroxybenzylpenicillin
amoxicillanyl
amoxicillin
p-Hydroxyampicillin
α-amino-p-hydroxybenzylpenicillin
8
Rivastigmineapproved, investigationalPhase 483123441-03-277991
Synonyms:
(S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate
123441-03-2
3-((1S)-1-(Dimethylamino)ethyl)phenyl N-ethyl-N-methylcarbamate
3-((1S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate
3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate
AB1004572
AC1L2U92
BIDD:GT0316
C11766
CHEMBL636
CID77991
Carbamic acid, N-ethyl-N-methyl-, 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester
Carbamic acid, ethylmethyl-, 3-((1S)-1-(dimethylamino)ethyl)phenyl ester
D03822
DB00989
ENA 713 free base
 
Ena 713 Free Base
Ethylmethylcarbamic acid 3-((1S)-1-(dimethylamino)ethyl)phenyl ester
Exelon
Exelon Patch
HMS2089H18
I06-2037
LS-172571
MolPort-003-666-662
NCGC00167531-01
Rivastigmine (JAN/USAN/INN)
Rivastigmine Hydrogen Tartrate
Rivastigmine [USAN:INN]
Rivastigmine hydrogen tartrate
SDZ 212-713
UNII-PKI06M3IW0
[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate
m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate
rivastigmine
9sodium fluorideapprovedPhase 41937681-49-4
10
Ketoprofenapproved, vet_approvedPhase 48522071-15-43825
Synonyms:
(+-)-3-Benzoyl-alpha-methylbenzeneacetic acid
(+-)-m-Benzoylhydratropic acid
154907-35-4
172964-50-0
19,583 RP
19583 RP
2-(3-Benzoylphenyl)propanoic acid
2-(3-Benzoylphenyl)propionic acid
2-(m-Benzoylphenyl)propionic acid
2-[3-(benzoyl)phenyl]propanoic acid
2-[3-(phenylcarbonyl)phenyl]propanoic acid
2-[3-Benzoylphenyl]propionic acid
22071-15-4
22161-86-0
3-BENZOYL-ALPHA-METHYLBENZENEACETIC ACID
3-Benzoyl-alpha-methylbenzeneacetic acid
3-Benzoyl-α-methylbenzeneacetic acid
3-Benzoylhydratropic acid
34016_FLUKA
34016_RIEDEL
AB00052249
AC-1486
AC1L1GST
AC1Q1LGA
Acide (benzoyl-3-phenyl)-2-propionique
Acide (benzoyl-3-phenyl)-2-propionique [French]
Actron
Alrheumat
Alrheumum
Alrheumun
Aneol
BIDD:GT0443
BIM-0050664.0001
BPBio1_000261
BRD-A97739905-001-05-9
BSPBio_000237
BSPBio_003037
Benzoylhydratropic Acid
Bio-0742
C01716
CCRIS 4508
CHEBI:6128
CHEMBL571
CID3825
CPD000040181
Capisten
D00132
D007660
DB01009
Dexal
DivK1c_000598
EINECS 244-759-8
EU-0100686
Epatec
FT-0082352
Fastum
HMS1568L19
HMS1921B12
HMS2089B16
HMS2092L19
HMS501N20
I01-3439
IDI1_000598
InChI=1/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)
Iso-K
K 1751
K0038
K1751_SIAL
K1751_SIGMA
K2012_SIAL
KBio1_000598
KBio2_001789
KBio2_004357
 
KBio2_006925
KBio3_002537
KBioGR_000435
KBioSS_001789
Kefenid
Ketoprofen
Ketoprofen (+-)
Ketoprofen (JP15/USP/INN)
Ketoprofen [USAN:INN:BAN:JAN]
Ketoprofene
Ketoprofene [INN-French]
Ketoprofeno
Ketoprofeno [INN-Spanish]
Ketoprofenum
Ketoprofenum [INN-Latin]
Ketopron
Ketoprophene
L'Acide (benzoyl-3-phenyl)-2-propionique
LS-28621
LS-7470
Lertus
Lopac0_000686
MLS000028446
MLS000079024
MLS001201752
MLS001306444
Menamin
Meprofen
MolPort-001-684-346
NCGC00015578-02
NCGC00015578-07
NCGC00094043-01
NCGC00094043-02
NCGC00094043-03
NCGC00094043-04
NINDS_000598
Oprea1_117113
Orudis
Orudis (TN)
Orudis (tn)
Orudis KT
Orudis, Oruvail, Ketoflam, Orudis KT, Ketoprofen
Orugesic
Oruvail
Oscorel
Prestwick0_000219
Prestwick1_000219
Prestwick2_000219
Prestwick3_000219
Prestwick_617
Profenid
RP 19583
RP, 19,583
RP-19583
RP19583
RU 4733
S1645_Selleck
SAM002264620
SMR000040181
SPBio_000952
SPBio_002158
SPECTRUM1501215
Spectrum2_000956
Spectrum3_001479
Spectrum4_000028
Spectrum5_001254
Spectrum_001309
Toprec
Toprek
UNII-90Y4QC304K
UNM-0000306100
ketoprofen
m-Benzoylhydratropic acid
racemic-Ketoprofen
11
Tramadolapproved, investigationalPhase 423227203-92-533741
Synonyms:
(+)-(R,R)-trans-Tramadol
(+)-Tramadol
(+)-trans-2-(Dimethylaminomethyl)-1-(m-methoxyphenyl)cyclohexanol
(+)-trans-Tramadol free ba
(1R,2R)-2-(dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexan-1-ol
(1R,2R)-2-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexanol
(1R,2R)-2-[(dimethylamino)methyl]-1-[3-(methyloxy)phenyl]cyclohexanol
27203-92-5
AC1L1Q6E
AC1Q59O2
AKOS005066335
Amanda
Amanda (TN)
BIDD:GT0075
C07153
CHEMBL1066
CID33741
Crispin
D08623
DB00193
EINECS 248-319-6
HMS2090D10
Jsp005295
LS-57115
 
LS-57116
MLS000333190
MolPort-002-507-778
NCGC00159343-02
Ralivia ER
Ralivia Flashtab
Ralivia flashtab
SMR000436547
STOCK4S-19075
Tradonal odis
Tramadol
Tramadol (INN)
Tramadol HCl
Tramadol HCl BP/EP
Tramadol [INN:BAN]
Tramadol hydrochloride
Tramadolum
Tramadolum [INN-Latin]
Tramal
Tramodol Hcl
Tridural
UNII-39J1LGJ30J
Ultram
Ultram ER
Zydol
tramadol
12
AcetaminophenapprovedPhase 4978103-90-21983
Synonyms:
4'-Hydroxyacetanilide
4'-hydroxyacetanilide
4-(Acetylamino)phenol
4-Acetamidophenol
4-Acetaminophenol
4-Hydroxyacetanilide
4-Hydroxyanilid kyseliny octove
4-acetamidophenol
A-Per
A.F. Anacin
AC1Q1KYJ
AC1Q1KYK
APAP
Abenol
Abensanil
Abrol
Abrolet
Acamol
Accu-Tap
Acenol
Acephen
Acertol
Aceta Elixir
Aceta Tablets
Acetaco
Acetagesic
Acetalgin
Acetaminofen
Acetaminophen
Acetaminophen Uniserts
Acetamol
Acetavance
Acetofen
Actamin
Actamin Extra
Actamin Super
Actifed Plus
Actimol
Actimol Chewable Tablets
Actimol Children'S Suspension
Actimol Infants' Suspension
Actimol Junior Strength Caplets
Actron
Afebrin
Afebryl
Aferadol
Algesidal
Algina
Algomol
Algotropyl
Allay
Alpiny
Alpinyl
Alvedon
Amadil
Aminofen
Aminofen Max
Anacin
Anacin 3
Anacin-3
Anacin-3 Extra Strength
Anadin dla dzieci
Anaflon
Analter
Anapap
Andox
Anelix
Anexsia
Anexsia 10/660
Anexsia 5/325
Anexsia 7.5/325
Anexsia 7.5/650
Anhiba
Anoquan
Anti-Algos
Antidol
Anuphen
Apacet
Apacet Capsules
Apacet Elixir
Apacet Extra Strength Caplets
Apacet Extra Strength Tablets
Apacet Regular Strength Tablets
Apadon
Apamid
Apamide
Apitrelal
Apo-Acetaminophen
Arfen
Arthralgen
Asetam
Asomal
Aspac
Aspirin Free Anacin Maximum Strength Caplets
Aspirin Free Anacin Maximum Strength Gel Caplets
Aspirin Free Anacin Maximum Strength Tablets
Aspirin-Free Anacin
Aspirin-Free Excedrin Caplets
Asplin
Atasol
Atasol Caplets
Atasol Drops
Atasol Forte Caplets
Atasol Forte Tablets
Atasol Oral Solution
Atasol Tablets
Atralidon
Babikan
Bacetamol
Bancap
Bancap Hc
Banesin
Bayer Select
Bayer Select Allergy-Sinus
Bayer Select Head Cold
Bayer Select Headache Pain
Bayer Select Maximum Strength Headache Pain Relief Formula
Bayer Select Menstrual Multi-Symptom
Bayer Select Sinus Pain Relief
Ben-u-ron
Benmyo
Bickie-mol
Biocetamol
Bucet
Butalbital
Butapap
CCRIS 3
CHEBI:46195
Cadafen
Calapol
Calmanticold
Calonal
Calpol
Capital
Capital with Codeine
Captin
Causalon
Cefalex
Cetadol
Children'S Acetaminophen Elixir Drops
Children'S Acetaminophen Oral Solution
Children'S Tylenol Chewable
Claradol Codeine
Clixodyne
Co-Gesic
Cod-Acamol Forte
Codabrol
Codalgin
Codapane
Codicet
Codisal
Codisal Forte
Codoliprane
Codral Pain Relief
Cofamol
Conacetol
Contac Cough & Sore Throat Formula
Contra-Schmerz P
Coricidin
Coricidin D
Coricidin Sinus
Cosutone
Croix Blanche
Cuponol
Curadon
Curpol
Custodial
D oliprane
Dafalgan
Dapa
Dapa X-S
Darocet
Darvocet
Darvocet-N 50
Datril
Datril Extra-Strength
Daygrip
Demilets
Deminofen
Democyl
Demogripal
Desfebre
Dhamol
Dhc Plus
Dial-a-gesic
Dial-alpha-gesic
Dimindol
Dirox
Disprol
Dol-Stop
Dolcor
Dolefin
Dolegrippin
Dolene AP-65
Dolene Ap-65
Dolgesic
Doliprane
Dolko
Dolofugin
Doloreduct
Dolorfug
Dolorol Forte
Dolorstop
Dolotec
Dolprone
Dorocoff
Dresan
Dristan Cold No Drowsiness
Dristancito
Drixoral Plus
Duaneo
Dularin
Duorol
Duracetamol
Duradyne Dhc
Durapan
Dymadon
Dymadon Co
Dymadon Forte
Dypap
Ecosetol
Elixodyne
Empracet
Endecon
Enelfa
Eneril
Esgic
Esgic-Plus
Eu-Med
Excedrin
Excedrin Caplets
Excedrin Extra Strength Caplets
Excipain
Exdol
Exdol Strong
Fanalgic
Farmadol
Febranine
Febrectal
Febrectol
Febrex
Febricet
Febridol
Febrilix
Febrin
Febrinol
Febro-Gesic
Febrolin
Femcet
Fendon
Fensum
Fepanil
Fever All
Feverall
Feverall Junior Strength
Feverall Sprinkle Caps Junior Strength
Fevor
Finimal
Finiweh
Fioricet
Fluparmol
Fortalidon P
Freka-cetamol
Gattaphen T
Gelocatil
Geluprane
Genapap
Genapap Children'S Elixir
Genapap Children'S Tablets
Genapap Extra Strength Caplets
Genapap Extra Strength Tablets
Genapap Regular Strength Tablets
Genebs
Genebs Extra Strength Caplets
Genebs Regular Strength Tablets
Genebs X-Tra
Geralgine-P
Gripin Bebe
Grippostad
Gynospasmine
Hedex
Helon N
Homoolan
Hy-Phen
Hycomine Compound
Hydrocet
Ildamol
Inalgex
Infadrops
Infants' Feverall
Influbene N
Injectapap
Intensin
Janupap
Jin Gang
Junior Disprol
KBio1_000660
Kataprin
Kinder Finimal
Korum
Kratofin simplex
L024125
Labamol
Lekadol
Lemgrip
Lemsip
Lestemp
Liqiprine
Liquagesic
Liquigesic Co
Liquiprin
Liquiprin Children'S Elixir
Liquiprin Infants" Drops
Lonarid
Lonarid Mono
Lorcet-Hd
Lortab
Lupocet
Lyteca
Lyteca Syrup
Magnidol
Malex N
Malgis
Malidens
Maxadol
Medigesic Plus
Medinol Paediatric
Medocodene
Melabon Infantil
Mexalen
Midol Maximum Strength
Midol PM Night Time Formula
Midol Regular Strength
Midol Teen Formula
Migraleve Yellow
Minafen
Minoset
Miralgin
Momentum
Mono Praecimed
 
Multin
N-(4-Hydroxyphenyl)acetamide
N-Acetyl-4-aminophenol
N-Acetyl-p-aminophenol
N-acetyl-p-aminophenol
NAPA
NCX 701
NEBS
NSC3991
Naldegesic
Napafen
Napap
Naprinol
Nealgyl
Nebs
Neo-Fepramol
NeoCitran
Neodol
Neodolito
Neopap
Neotrend
Neuridon
New Cortal for Children
NilnOcen
Nina
No-Febril
Nobedon
Nodolex
Noral
Norcet
Norco
O-Acetaminophenol
Ofirmev
Oltyl
Oralgan
Oraphen-PD
Ortensan
Oxycet
Oxycocet
Oxycodone 2.5/Apap 500
Oxycodone 5/Apap 500
PCM Paracetamol Lichtenstein
Paceco
Pacemo
Pacemol
Pacet
Pacimol
Paedialgon
Paedol
Painex
Paldesic
Pamol
Panacete
Panadeine
Panadeine Co
Panadiene
Panado-Co
Panado-Co Caplets
Panadol
Panadol Extra Strength
Panadol Junior Strength Caplets
Panadol Maximum Strength Caplets
Panadol Maximum Strength Tablets
Panale ve
Panaleve
Panamax
Panasorb
Panasorbe
Panets
Panex
Panodil
Panofen
Pantalgin
Papa-Deine
Papa-Deine #3
Papa-Deine #4
Para-Suppo
Para-Tabs
Paracemol
Paracenol
Paracet
Paracetamol
Paracetamol AL
Paracetamol Antipanin P
Paracetamol BC
Paracetamol Basics
Paracetamol DC
Paracetamol Dr. Schmidgall
Paracetamol Fecofar
Paracetamol Genericon
Paracetamol Hanseler
Paracetamol Harkley
Paracetamol Heumann
Paracetamol Hexal
Paracetamol Italfarmaco
Paracetamol Nycomed
Paracetamol PB
Paracetamol Raffo
Paracetamol Ratiopharm
Paracetamol Rosch
Paracetamol Saar
Paracetamol SmithKline Beecham
Paracetamol Stada
Paracetamol Winthrop
Paracetamol von ct
Paracetamole
Paracetamolo
Paracetamolum
Paracetanol
Paracetol
Paracin
Paracod
Paracodol
Paracétamol
Parador
Paradrops
Parakapton
Parake
Paralen
Paralief
Paralink
Paralyoc
Paramol
Paramolan
Paranox
Parapan
Parasedol
Parasin
Paraspen
Parcetol
Parelan
Parmol
Parogal
Paroma
Pasolind
Pasolind N
Pe-Tam
Pediapirin
Pediatrix
Pedric
Percocet
Percocet-5
Percocet-Demi
Percogesic with Codeine
Perdolan Mono
Perfalgan
Phenaphen
Phenaphen Caplets
Phenaphen W/Codeine
Phendon
Phenipirin
Phogoglandin
Phrenilin
Phrenilin Forte
Pinex
Piramin
Pirinasol
Plicet
Polmofen
Predimol
Predualito
Prestwick_13
Prodol
Prompt
Prontina
Propacet
Propacet 100
Proval #3
Puernol
Pulmofen
Pyregesic-C
Pyrigesic
Pyrinazine
Pyromed
Quiet World
Redutemp
Reliv
Remedol
Rhinex D-Lay Tablets
Rivalgyl
Robigesic
Robitussin Night Relief
Rockamol Plus
Rounox
Roxicet
Roxicet 5/500
Roxilox
RubieMol
Rubophen
Rupemol
SK-Apap
SPBio_002836
Salzone
Sanicet
Sanicopyrine
Scanol
Scentalgyl
Scherzatabletten Rezeptur 534
Schmerzex
Sedalito
Sedapap
Semolacin
Servigesic
Seskamol
Setakop
Setamol
Setol
Sifenol
Sinaspril
Sine-Off Sinus Medicine Caplets
Sinedol
Sinmol
Sinubid
Snaplets-FR
Spalt N
Spalt fur die nacht
St Joseph Aspirin-Free
St Joseph Aspirin-Free for Children
St. Joseph Cold Tablets for Children
St. Joseph Fever Reducer
Stanback
Stopain
Sudafed Severe Cold Formula
Sudafed Sinus
Sunetheton
Supac
Supadol mono
Supofen
Suppap
Suppap-120
Suppap-325
Suppap-650
Supramol-M
Synalgos-Dc-A
TYL
Tabalgin
Tachiprina
Talacen
Tapanol
Tapanol Extra Strength Caplets
Tapanol Extra Strength Tablets
Tapar
Tavist Allergy/Sinus/Headache
Tazamol
Temlo
Tempanal
Tempra
Tempra Caplets
Tempra Chewable Tablets
Tempra D.S
Tempra Drops
Tempra Syrup
Tencon
Termacet
Termalgin
Termalgine
Termofren
TheraFlu
Tibinide
Tibizide
Tiffy
Tisin
Tisiodrazida
Titralgan
Tizide
Tocris-1706
Toximer P
Tralgon
Treupel N
Treupel mon
Treuphadol
Triad
Triaminic Sore Throat Formula
Triaprin
Tricoton
Tussapap
Ty lenol
Tycolet
Tylenol
Tylenol (TN)
Tylenol Allergy Sinus
Tylenol Arthritis Extended Relief
Tylenol Caplets
Tylenol Children'S Chewable Tablets
Tylenol Children'S Elixir
Tylenol Children'S Suspension Liquid
Tylenol Drops
Tylenol Elixir
Tylenol Extra Strength Adult Liquid Pain Reliever
Tylenol Extra Strength Caplets
Tylenol Extra Strength Gelcaps
Tylenol Extra Strength Tablets
Tylenol Gelcaps
Tylenol Infants Drops
Tylenol Infants" Suspension Drops
Tylenol Junior Strength Caplets
Tylenol Junior Strength Chewable Tablets
Tylenol Regular Strength Caplets
Tylenol Regular Strength Tablets
Tylenol Tablets
Tylex
Tylex CD
Tylol
Tylox
Tylox-325
Tymol
Ultracet
Upsanol
Utragin
Valadol
Valgesic
Valorin
Valorin Extra
Vanquish
Veralgina
Vermidon
Verpol
Viclor Richet
Vicodin
Vicodin Es
Vicodin Hp
Vips
Viruflu
Vivimed
Volpan
Wygesic
Zatinol
Zolben
acetaminofén
acétaminophène
alpha-Per
p-(Acetylamino)phenol
p-Acetamidophenol
p-Acetaminophenol
p-Acetylaminophenol
p-Hydroxyacetanilide
p-Hydroxyphenolacetamide
p-acetamidophenol
p-acetaminophenol
p-hydroxy-acetanilid
p-hydroxyacetanilide
p-hydroxyphenolacetamide
13
Doxycyclineapproved, investigational, vet_approvedPhase 4237564-25-054671203
Synonyms:
(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
10597-92-9
17086-28-1 (mono-hydrate)
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)
24390-14-5
41411-66-9 (6-epimer, mono-hydrochloride)
5-Hydroxy-alpha-6-deoxytetracycline
5-hydroxy-α-6-deoxytetracycline
564-25-0
6-Deoxyoxytetracycline
6-Deoxytetracycline
6-alpha-Deoxy-5-oxytetracycline
6-alpha-deoxy-5-oxytetracycline
69935-17-7 (mono-hydrochloride, di-hydrate)
6alpha-Deoxy-5-oxytetracycline
6alpha-deoxy-5-oxytetracycline
6α-deoxy-5-oxytetracycline
7164-70-7
7264-10-0
94088-85-4 (calcium salt (1:2))
AB08 (*Fosfatex)
AC1NQXW7
AC1NS4CW
AC1NUYS8
AC1O8PYM
Alti-Doxycycline
Anhydrous doxycycline
Apo-Doxy
Atridox
Azudoxat
BCBcMAP01_000024
BIDD:GT0146
BMY-28689
BPBio1_000951
BSPBio_000863
BSPBio_001936
BU-3839T
C06973
CHEBI:50845
CHEMBL1433
CID5281011
CID5353597
CID5463943
CID6713981
CPD001550033
D07876
DB00254
DMSC (*Fosfatex)
DOXCYCLINE ANHYDROUS
DOXY
DOXYCYCLINE CALCIUM
DOXYCYCLINE MONOHYDRATE
Deoxymykoin
DivK1c_000345
Dossiciclina
Dossiciclina [DCIT]
Doxcycline anhydrous
Doxiciclina
Doxiciclina [INN-Spanish]
Doxiciclina [Italian]
Doxitard
Doxivetin
Doxy-Caps
Doxy-Puren
Doxy-Tabs
Doxycen
Doxychel
Doxychel (TN)
Doxycin
Doxycyclin
Doxycycline (200mg/day) or Placebo
 
Doxycycline (INN)
Doxycycline (TN)
Doxycycline (anhydrous)
Doxycycline (internal use)
Doxycycline Hyclate
Doxycycline Monohydrate
Doxycycline anhydrous
Doxycycline hyclate
Doxycycline-Chinoin
Doxycyclinum
Doxycyclinum [INN-Latin]
Doxysol
Doxytec
Doxytetracycline
EINECS 209-271-1
GS-3065 (*monohydrate)
HMS2090E06
HSDB 3071
Hydramycin
IDI1_000345
Investin
Jenacyclin
KBio1_000345
KBio2_001287
KBio2_003855
KBio2_006423
KBio3_001156
KBioGR_001133
KBioSS_001287
LS-187766
LS-93868
Liviatin
Lopac0_000405
MolPort-002-507-423
Monodox
Monodox (*monohydrate)
NCGC00161602-01
NCGC00161602-03
NCGC00161602-04
NCGC00167961-01
NCGC00179395-01
NINDS_000345
NSC633557
Novo-Doxylin
Nu-Doxycycline
Oracea
Prestwick0_000852
Prestwick1_000852
Prestwick2_000852
Prestwick3_000852
Ronaxan
SAM002589932
SMP1_000107
SPBio_000246
SPBio_002784
STOCK1N-34341
Spanor
Spectrum2_000143
Spectrum3_000408
Spectrum4_000527
Spectrum5_000947
Spectrum_000807
Supracyclin
UNII-334895S862
UPCMLD-DP021
UPCMLD-DP021:001
Vibra-tabs
Vibramycin
Vibramycin (*monohydrate)
Vibramycin Novum
Vibramycine
Vibravenos
Vivox (*Hyclate)
alpha-6-Deoxy-5-hydroxytetracycline
alpha-6-Deoxyoxytetracycline
alpha-Doxycycline
doxycycline
14
IbuprofenapprovedPhase 450115687-27-13672
Synonyms:
(+-)-2-(P-Isobutylphenyl)propionic acid
(+-)-Ibuprofen
(+-)-P-Isobutylhydratropic acid
(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid
(4-Isobutylphenyl)-alpha-methylacetic acid
(RS)-ibuprofen
139466-08-3
15687-27-1
2-(4-Isobutylphenyl)propanoic acid
4-Isobutylhydratropic acid
58560-75-1
AC-11312
AC1L1GGE
AC1Q1P84
AC1Q1P85
ACHES-N-PAIN
ARONIS23835
Act-3
Actiprofen
Adex 200
Adran
Advil
Advil (TN)
Advil Liqui-Gels
Ak+C2278tren
Alaxan
Algofen
Am-Fam 400
Amelior
Amersol
Amibufen
Anafen
Anco
Andran
Anflagen
Antagil
Antalfene
Antarene
Antiflam
Apo-Ibuprofen
Apsifen
Apsifen-F
Artofen
Artril
Artril 300
BB_SC-1358
BIDD:GT0050
BRN 2049713
Balkaprofen
Betaprofen
Bloom
Bluton
Brofen
Brufanic
Brufen
Brufen 400
Bruflam
Brufort
Buburone
Bufeno
Bufigen
Bukrefen
Bupron
Buracaps
Burana
Butylenin
C01588
C13H18O2
CCRIS 3223
CHEBI:5855
CHEMBL521
CID3672
CPD000058184
Cap-Profen
Carol
Cesra
Children's Advil
Children's Elixsure
Children's Ibuprofen
Children's Motrin
Citalgan
Cobo
Codral
Combiflam
Cunil
D00126
D007052
DB01050
DOLO PUREN
Daiprophen
Dalsy
Dansida
Deep Relief
Dentigoa
Dibufen
Dignoflex
Dolgin
Dolgirid
Dolgit
Dolibu
Dolmaral
Dolo-Dolgit
Dolo-dolgit
Dolocyl
Dolofen
Dolofen-F
Dolofin
Dolofort
Dologel
Dolomax
Doloren
Dolormin
Doltibil
Dolven
Donjust B
Dorival
Drin
Duafen
Duobrus
Dura-Ibu
Duralbuprofen
Dysdolen
EU-0100691
Easifon
Ebufac
Emflam
Emflam-200
Emodin
Epobron
Eputex
Ergix
Esprenit
Exneural
Faspic
Femadon
Femafen
Femapirin
Femidol
Fenbid
Fenbid Spansule
Fendol
Fenspan
Fibraflex
Gelufene
Gofen
Grefen
Gynofug
HMS1920F15
HMS2089P05
HMS2091N03
HMS502M09
HSDB 3099
Haltran
I 4883
I01-7039
I0415
I4883_SIGMA
I7905_SIAL
IB-100
IDI1_000887
IP 82
IP-82
IP82
Ibol
Ibren
Ibu
Ibu-Attritin
Ibu-Slo
Ibu-Tab
Ibu-Tab 200
Ibu-attritin
Ibu-slo
Ibu-slow
Ibubest
Ibubeta
Ibucasen
Ibudol
 
Ibudolor
Ibufen
Ibuflamar
Ibufug
Ibugel
Ibugen
Ibugesic
Ibuhexal
Ibulagic
Ibular
Ibulav
Ibuleve
Ibulgan
Ibumed
Ibumerck
Ibumetin
Ibupirac
Ibuprin
Ibuprocin
Ibuprofen
Ibuprofene
Ibuprofeno
Ibuprofenum
Ibuprohm
Ibuprophen
Ibusal
Ibutid
Ifen
Inabrin
Inflam
Inoven
Ipren
Irfen
Isodol
Jenaprofen
Junifen
Junior Strength Advil
Junior Strength Ibuprofen
Junior Strength Motrin
KBio1_000887
KBio2_001329
KBio2_003897
KBio2_006465
KBio3_001390
Kesan
Kratalgin
LS-7454
Lamidon
Lebrufen
Librofem
Lidifen
Liptan
Lopane
MLS000069733
MLS001146965
Malafene
Manypren
Medipren
Melfen
Mensoton
Midol
Midol 200
Moment
Motrin
Motrin (TN)
Motrin IB
Mynosedin
NCI60_002065
NINDS_000887
NSC 256857
NSC256857
Nagifen-D
Napacetin
Narfen
Neo-Helvagit
Neo-Mindol
NeoProfen
Neobrufen
Nerofen
Noalgil
Nobafon
Nobfelon
Nobfen
Nobgen
Noritis
Norton
Novadol
Novo-Profen
Novogent
Novogent N
Novoprofen
Nuprilan
Nuprin
Nurofen
Optifen
Opturem
Oralfene
Ostarin
Ostofen
Ozonol
P-Isobutylhydratropic Acid
Paduden
Panafen
Pantrop
Para-Isobutylhydratropic Acid
Paxofen
Pedia-Profen
PediaProfen
Pediaprofen
Pediatric Advil
Perofen
Proartinal
Profen
Proflex
Provon
Quadrax
R.D. 13621
RD 13621
Rafen
Ranofen
Rebugen
Relcofen
Rhinadvil
Rofen
Roidenin
Rufen
Rufin
Rupan
SAM002264619
SMR000058184
SPBio_000178
STK177358
Sadefen
Salivia
Salprofen
Seclodin
Sednafen
Seklodin
Seskafen
Siyafen
Solpaflex
Solufen
Stelar
Sugafen
Suprafen
Suspren
Syntofene
TL8001184
Tab-Profen
Tabalon
Tabalon 400
Tatanal
Tempil
Tofen
Togal N
Tonal
Trendar
U 18573
U-18,573
U-18573
UCB 79171
Unipron
Upfen
Uprofen
Urem
VUFB 9649
Zafen
Zofen
alpha-(4-Isobutylphenyl)propionate
alpha-(4-Isobutylphenyl)propionic acid
alpha-(P-Isobutylphenyl)propionic acid
alpha-p-Isobutylphenylpropionate
alpha-p-Isobutylphenylpropionic acid
ibuprofen
p-Isobutyl-2-phenylpropionate
p-Isobutyl-2-phenylpropionic acid
p-Isobutylhydratropate
p-Isobutylhydratropic acid
15
Chlorhexidineapproved, vet_approvedPhase 447255-56-19552079, 2713
Synonyms:
1,1 inverted exclamation marka-Hexamethylenebis[5-(4-chlorophenyl)biguanide]
1,1'-Hexamethylene bis(5-(P-chlorophenyl)biguanide)
1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)
1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide)
1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide
1,6-Bis(5-(p-chlorophenyl)biguandino)hexane
1,6-Bis(p-chlorophenyldiguanido)hexane
1,6-Di(4'-chlorophenyldiguanido)hexane
1,6-Di(N-p-chlorophenyldiguanido)hexane
24798_FLUKA
282227_ALDRICH
348031_ALDRICH
4-12-00-01201 (Beilstein Handbook Reference)
55-56-1
AB00053427
AB1003159
AVAGARD
BPBio1_000272
BRN 2826432
BSPBio_000246
BSPBio_001977
C06902
C22H30Cl2N10
CAS-55-56-1
CCRIS 9230
CHEBI:3614
CHEMBL790
CID9552079
Chlorhexidin
Chlorhexidin [Czech]
Chlorhexidine
Chlorhexidine (INN)
Chlorhexidine Base
Chlorhexidine [INN:BAN]
Chlorhexidine gluconate
Chlorhexidinum
Chlorhexidinum [INN-Latin]
Cloresidina
Cloresidina [DCIT]
Clorhexidina
Clorhexidina [INN-Spanish]
D07668
DB00878
Decanoylacetaldehyde Sodium Sulfide
Dentisept [veterinary]
Dentisept [veterinary] (TN)
DivK1c_000761
EINECS 200-238-7
Fimeil
HMS1568M08
HSDB 7196
Hexadol
Hibiclens
Hibispray
Hibistat
I06-0621
I14-0050
IDI1_000761
 
KBio1_000761
KBio2_000717
KBio2_003285
KBio2_005853
KBio3_001197
KBioGR_000774
KBioSS_000717
LS-43917
Lisium (*Dihydrochloride*)
MK-412A
MLS001332387
MLS001332388
MLS002154209
Merfen-incolore
Merfen-incolore (TN)
MolPort-002-541-741
N',N'''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(imidodicarbonimidic diamide)]
N,N''''-hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)]
N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradeca- nediimidamide
N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide
N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide
NCGC00016246-01
NCGC00091025-01
NCGC00091025-02
NINDS_000761
NSC526936
Nolvasan
Nolvasan (*Diacetate*)
Novalsan
Oro-Clense
Peridex
Periogard
Prestwick0_000143
Prestwick1_000143
Prestwick2_000143
Prestwick3_000143
Prestwick_53
QTL1_000020
Rotersept
SMR000857146
SPBio_000210
SPBio_002185
STK089248
STOCK1S-18831
Savloclens
Savlon babycare
Sebidin A
Sodium Houttuyfonamide
Soretol
Spectrum2_000135
Spectrum3_000339
Spectrum4_000277
Spectrum5_001322
Spectrum_000237
Sterido
Sterilon
Superspray
Tubulicid
UNII-R4KO0DY52L
chlorhexidine
16Protective AgentsPhase 4, Phase 3, Early Phase 17190
17Anti-Infective AgentsPhase 4, Phase 3, Phase 2, Phase 121402
18Cariostatic AgentsPhase 4, Phase 3318
19FluoridesPhase 4, Phase 3, Phase 2438
20Anti-Infective Agents, LocalPhase 4, Phase 31785
21Anti-Anxiety AgentsPhase 4, Phase 31816
22AnalgesicsPhase 4, Phase 311287
23PropolisPhase 419
24Pharmaceutical SolutionsPhase 47793
25calcium channel blockersPhase 4, Phase 31940
26Central Nervous System DepressantsPhase 4, Phase 3, Phase 2, Early Phase 112806
27Anti-Inflammatory AgentsPhase 4, Phase 310355
28Dermatologic AgentsPhase 4, Phase 2, Early Phase 15674
29ListerinePhase 4193
30Tranquilizing AgentsPhase 4, Phase 34164
31Anti-Obesity AgentsPhase 4, Phase 3411
32Psychotropic DrugsPhase 4, Phase 36279
33Calcium, DietaryPhase 4, Phase 3, Phase 2, Phase 15525
34AnticonvulsantsPhase 4, Phase 32620
35Neurotransmitter Uptake InhibitorsPhase 4, Phase 33464
36Antiprotozoal AgentsPhase 4, Phase 31986
37Antiparasitic AgentsPhase 4, Phase 32127
38Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Early Phase 122776
39Adrenergic AgentsPhase 4, Phase 35140
40Autonomic AgentsPhase 4, Phase 3, Early Phase 19774
41Neurotransmitter AgentsPhase 4, Phase 3, Early Phase 117734
42Dopamine Uptake InhibitorsPhase 4, Phase 31305
43Dopamine AgentsPhase 4, Phase 33759
44Central Nervous System StimulantsPhase 4, Phase 32132
45Cholinergic AgentsPhase 43846
46Cholinesterase InhibitorsPhase 4570
47incobotulinumtoxinAPhase 4635
48Neuromuscular AgentsPhase 41129
49onabotulinumtoxinAPhase 4626
50Anti-Bacterial AgentsPhase 4, Phase 2, Phase 310884

Interventional clinical trials:

(show top 50)    (show all 132)
idNameStatusNCT IDPhase
1Adjunctive Antimicrobial Therapy of Periodontitis: Long-Term Effects on Disease Progression and Oral Microbiological ColonizationCompletedNCT00707369Phase 4
2Antimicrobial Therapy as Adjunct to Periodontal Treatment: Effect of TimingCompletedNCT02197260Phase 4
3Prefabricated Endodontic Posts: Glass Fiber Versus Titanium - A Randomized Controlled Pilot- TrialCompletedNCT01520766Phase 4
4Effects of Rivastigmine Patch on Activities of Daily Living and Cognition in Patients With Severe Dementia of the Alzheimer's Type (ACTION) (Study Protocol CENA713DUS44, NCT00948766) and a 24 Week Open-label Extension to Study CENA713DUS44CompletedNCT00948766Phase 4
5A Long-term Efficacy, Safety, and Tolerability Study of BOTOX® in Patients With Chronic MigraineCompletedNCT01516892Phase 4
6Study Comparing Outcomes for Patients With Treatment Resistant Depression Who Receive VNS Therapy at Different DosesCompletedNCT00305565Phase 4
7MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization StudyCompletedNCT02424097Phase 4
8Propolis Improves Glycemic Control in Subjects With Type 2 Diabetes and Chronic PeriodontitisCompletedNCT02794506Phase 4
9TM vs TSV Implants Loaded Early vs Conventional in Anterior and Posterior AreasRecruitingNCT02158377Phase 4
10Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or PlaceboRecruitingNCT00351611Phase 4
11Tramadol Hydrochloride and Dexketoprofen Trometamol for the Oral Treatment of Moderate to Severe Acute Pain Following Removal of Impacted Lower Third MolarRecruitingNCT02777970Phase 4
12Efficacy and Safety Study of BOTOX® Compared to Topiramate for the Prevention of Chronic Migraine in AdultsActive, not recruitingNCT02191579Phase 4
13Gingival Recession Coverage With and Without EmdogainActive, not recruitingNCT02230787Phase 4
14Effect of Postsurgical Systemic Doxycycline After Regenerative Periodontal TherapyTerminatedNCT01030666Phase 4
15Periodontal Disease and Cardiovascular DiseaseUnknown statusNCT00763165Phase 3
16A Study of the Safety and Effectiveness of Rabeprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Pediatric PatientsCompletedNCT00787891Phase 3
17DHA (Docosahexaenoic Acid), an Omega 3 Fatty Acid, in Slowing the Progression of Alzheimer's DiseaseCompletedNCT00440050Phase 3
18Valproate in Dementia (VALID)CompletedNCT00071721Phase 3
19Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Non-Carrier)CompletedNCT00574132Phase 3
20Efficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive DisorderCompletedNCT01436162Phase 3
21Safety Study of AVP-923 in the Treatment of IEED (Involuntary Emotional Expression Disorder) Also Known as Pseudobulbar Affect (Episodes of Uncontrolled Crying and/or Laughter)CompletedNCT00056524Phase 3
22NINDS CRC Chronic Migraine Treatment TrialCompletedNCT00772031Phase 3
23Safety and Efficacy of AVP-923 for Pseudobulbar Affect in Multiple Sclerosis PatientsCompletedNCT00050232Phase 3
24Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed GlioblastomaCompletedNCT01480479Phase 3
25DFN-02 Open Label Safety Study in Patients With Acute MigraineCompletedNCT02279082Phase 3
26Efficacy and Safety of 20 mg Sumatriptan Powder Delivered Intranasally With the Bi-directional Device Compared With 100 mg Sumatriptan Tablets in Adults With Acute Migraine With or WithoutCompletedNCT01667679Phase 3
27Safety & Efficacy of a Single Dose of Sumatriptan Powder Delivered Intranasally With the Bi-directional Device in Adults With Acute MigraineCompletedNCT01462812Phase 3
28Safety & Efficacy of Eslicarbazepine Monotherapy in Sub.w/Partial Epilepsy Not Well Controlled by Current AntiepilepticCompletedNCT01091662Phase 3
29Dose Response Study of Zonegran in Patients With Newly Diagnosed EpilepsyCompletedNCT00056576Phase 3
30Safety And Efficacy Study Of Once Daily Controlled Release Pregabalin In The Treatment Of Patients With Postherpetic NeuralgiaCompletedNCT01270828Phase 3
31Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast CancerCompletedNCT00083304Phase 3
32An Open-Labeled, Extended-Use of XERECEPT (hCRF) for Patients in Studies NTI 0302, 0303, or Other Designated StudiesCompletedNCT00226655Phase 3
33XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain TumorsCompletedNCT00088166Phase 3
34Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline ChemotherapyCompletedNCT00247975Phase 2, Phase 3
35PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine LeiomyomataCompletedNCT01629563Phase 3
36Study of Lamotrigine to Treat Ménière's DiseaseRecruitingNCT02158585Phase 3
37Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory LossRecruitingNCT02008357Phase 3
38Efficacy, Safety, and Tolerability of Oral Ubrogepant in the Acute Treatment of MigraineRecruitingNCT02867709Phase 3
39Efficacy, Safety, and Tolerability of Multiple Dosing Regimens of Oral AGN-241689 in Episodic Migraine PreventionRecruitingNCT02848326Phase 2, Phase 3
40Phase 3b Continuation Study of the Safety and Efficacy of Prophylactic BAX 855 in PTPs With Severe Hemophilia ARecruitingNCT01945593Phase 3
41Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) PatientsRecruitingNCT02796261Phase 3
42Chemotherapy With or Without Bevacizumab or Lapatinib to Treat Operable Oesophagogastric CancerRecruitingNCT00450203Phase 2, Phase 3
43Micronized dHACM Injectable for the Treatment of Plantar FasciitisRecruitingNCT02427191Phase 2, Phase 3
44A Study of LY2951742 in Participants With Episodic Cluster HeadacheRecruitingNCT02397473Phase 3
45Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus PlaceboActive, not recruitingNCT01900665Phase 3
46Open-Label Extension Study of the Long-Term Effects of Migalastat HCL in Patients With Fabry DiseaseActive, not recruitingNCT02194985Phase 3
47A Study of Palbociclib (PD-0332991) + Letrozole vs. Letrozole For 1st Line Treatment Of Postmenopausal Women With ER+/HER2- Advanced Breast Cancer (PALOMA-2)Active, not recruitingNCT01740427Phase 3
48Evaluation of LY2951742 in the Prevention of Chronic MigraineActive, not recruitingNCT02614261Phase 3
49Evaluation of LY2951742 in the Prevention of Episodic Migraine- the EVOLVE-1 StudyActive, not recruitingNCT02614183Phase 3
50Efficacy and Safety of Eslicarbazepine Acetate (BIA 2-093) as Adjunctive Therapy for Refractory Partial SeizuresActive, not recruitingNCT00988429Phase 3

Search NIH Clinical Center for Dent Disease


Cochrane evidence based reviews: dent disease

Genetic Tests for Dent Disease

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Genetic tests related to Dent Disease:

id Genetic test Affiliating Genes
1 Dent Disease 126 24 CLCN5
2 Dent's Disease26
3 Dent Disease24 OCRL

Anatomical Context for Dent Disease

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MalaCards organs/tissues related to Dent Disease:

35
Kidney, Bone, Breast, Brain, Testes, Endothelial, Colon

Animal Models for Dent Disease or affiliated genes

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MGI Mouse Phenotypes related to Dent Disease:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.1CLCN1, CLCN4, CLCN5, CLCN7, CLCNKB, CLDN16
2MP:00053676.1CLCN4, CLCN5, CLCN7, CLCNKB, CLDN16, CUBN

Publications for Dent Disease

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Articles related to Dent Disease:

(show all 40)
idTitleAuthorsYear
1
Phenotypic variability of Dent disease in a large New Zealand kindred. (27699523)
2017
2
Does Dent disease remain an underrecognized cause for young boys with focal glomerulosclerosis? (27324082)
2016
3
Functional and transport analyses of CLCN5 genetic changes identified in Dent disease patients. (27117801)
2016
4
Glomerular Pathology in Dent Disease and Its Association with Kidney Function. (27697782)
2016
5
Observations of a large Dent disease cohort. (27342959)
2016
6
Phenotype of Dent Disease in a Cohort of Indian Children. (27889724)
2016
7
Proteinuria in Dent disease: a review of the literature. (27757584)
2016
8
Dent Disease in Chinese Children and Findings from Heterozygous Mothers: Phenotypic Heterogeneity, Fetal Growth, and 10 Novel Mutations. (27174143)
2016
9
Double Xp11.22 deletion including SHROOM4 and CLCN5 associated with severe psychomotor retardation and Dent disease. (25670966)
2015
10
Mutation Update of the Clcn5 Gene Responsible for Dent Disease 1. (25907713)
2015
11
Dent disease in children: diagnostic and therapeutic considerations. (26308078)
2015
12
Nephrolithiasis, kidney failure and bone disorders in Dent disease patients with and without CLCN5 mutations. (26389017)
2015
13
Muscle involvement in Dent disease 2. (24912603)
2014
14
Expanding the phenotype of proteinuria in Dent disease. A case series. (24810952)
2014
15
Clinical utility gene card for: Dent disease (Dent-1 and Dent-2). (24619144)
2014
16
Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients. (23572577)
2013
17
Japanese Dent disease has a wider clinical spectrum than Dent disease in Europe/USA: genetic and clinical studies of 86 unrelated patients with low-molecular-weight proteinuria. (24081861)
2013
18
Suppression of intestinal calcium entry channel TRPV6 by OCRL, a lipid phosphatase associated with Lowe syndrome and Dent disease. (22378746)
2012
19
A patient with Dent disease and features of Bartter syndrome caused by a novel mutation of CLCN5. (21932010)
2012
20
From Lowe syndrome to Dent disease: correlations between mutations of the OCRL1 gene and clinical and biochemical phenotypes. (21031565)
2011
21
Heterogeneity in the processing of CLCN5 mutants related to Dent disease. (21305656)
2011
22
Mouse model for Lowe syndrome/Dent Disease 2 renal tubulopathy. (21183592)
2011
23
OCRL1 mutation in a boy with Dent disease, mild mental retardation, but without cataracts. (21822997)
2011
24
Novel mutations of the CLCN5 gene including a complex allele and A 5' UTR mutation in Dent disease 1. (19673950)
2009
25
Hydrochlorothiazide-induced tubulointerstitial nephritis in a patient with Dent disease. (25984010)
2009
26
Growth hormone improves growth rate and preserves renal function in Dent disease. (18540256)
2008
27
Renal manifestations of Dent disease and Lowe syndrome. (18038239)
2008
28
Effect of hydrochlorothiazide on urinary calcium excretion in dent disease: an uncontrolled trial. (18976849)
2008
29
Dent disease presenting as partial Fanconi syndrome and hypercalciuria. (18235437)
2008
30
Hypothesis: Dent disease is an underrecognized cause of focal glomerulosclerosis. (17702731)
2007
31
OCRL1 mutations in patients with Dent disease phenotype in Japan. (17384968)
2007
32
Novel OCRL1 mutations in patients with the phenotype of Dent disease. (17162149)
2006
33
Dent disease with mutations in OCRL1. (15627218)
2005
34
A 3-year-old child with proteinuria and nephrocalcinosis. Suspicion of Dent disease. (15365802)
2004
35
Megalin and proximal renal tubular dysfunction in Dent disease. (15338396)
2004
36
Examination of megalin in renal tubular epithelium from patients with Dent disease. (15052463)
2004
37
Dent disease-like phenotype and the chloride channel ClC-4 (CLCN4) gene. (15264294)
2004
38
Characterization of novel promoter and enhancer elements of the mouse homologue of the Dent disease gene, CLCN5, implicated in X-linked hereditary nephrolithiasis. (10373326)
1999
39
Cloning and characterization of CLCN5, the human kidney chloride channel gene implicated in Dent disease (an X-linked hereditary nephrolithiasis). (8575751)
1995
40
Dent Disease (22876375)
1993

Variations for Dent Disease

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UniProtKB/Swiss-Prot genetic disease variations for Dent Disease:

69 (show all 28)
id Symbol AA change Variation ID SNP ID
1CLCN5p.Gly57ValVAR_001616rs151340629
2CLCN5p.Leu200ArgVAR_001617rs151340622
3CLCN5p.Gly512ArgVAR_001621
4CLCN5p.Ser520ProVAR_001622rs151340623
5CLCN5p.Glu527AspVAR_001623
6CLCN5p.Gly179AspVAR_065591
7CLCN5p.Ser203LeuVAR_065592
8CLCN5p.Gly212AlaVAR_065593
9CLCN5p.Cys219ArgVAR_065594
10CLCN5p.Cys221ArgVAR_065595
11CLCN5p.Leu225ProVAR_065596rs273585645
12CLCN5p.Gly260ValVAR_065597rs151340630
13CLCN5p.Glu267AlaVAR_065598
14CLCN5p.Ser270GlyVAR_065600
15CLCN5p.Ser270ArgVAR_065601
16CLCN5p.Tyr272CysVAR_065602rs273585644
17CLCN5p.Phe273LeuVAR_065603
18CLCN5p.Leu278PheVAR_065604rs273585648
19CLCN5p.Asn340LysVAR_065605rs273585646
20CLCN5p.Gly462AspVAR_065606
21CLCN5p.Leu469ProVAR_065607
22CLCN5p.Gly513GluVAR_065608
23CLCN5p.Gly513ArgVAR_065609rs273585647
24CLCN5p.Arg516TrpVAR_065610rs797044812
25CLCN5p.Ser545AsnVAR_065612
26CLCN5p.Lys546GluVAR_065613
27CLCN5p.Trp547GlyVAR_065614rs273585650
28CLCN5p.Thr657SerVAR_065615rs144207967

Clinvar genetic disease variations for Dent Disease:

5 (show all 39)
id Gene Variation Type Significance SNP ID Assembly Location
1OCRLNM_000276.3(OCRL): c.1436A> G (p.Tyr479Cys)SNVPathogenicrs137853262GRCh37Chr X, 128701310: 128701310
2OCRLNM_000276.3(OCRL): c.952C> T (p.Arg318Cys)SNVLikely pathogenic, Pathogenicrs137853263GRCh37Chr X, 128696373: 128696373
3CLCN5NM_001127899.3(CLCN5): c.1047G> A (p.Trp349Ter)SNVPathogenicrs151340620GRCh37Chr X, 49851017: 49851017
4CLCN5NM_000084.4(CLCN5): c.1942C> T (p.Arg648Ter)SNVPathogenicrs151340621GRCh37Chr X, 49855335: 49855335
5CLCN5NM_001127899.3(CLCN5): c.809T> G (p.Leu270Arg)SNVPathogenicrs151340622GRCh37Chr X, 49846380: 49846380
6CLCN5NM_001127899.3(CLCN5): c.1768T> C (p.Ser590Pro)SNVPathogenicrs151340623GRCh37Chr X, 49854796: 49854796
7CLCN5NM_000084.4(CLCN5): c.731C> T (p.Ser244Leu)SNVLikely pathogenic, Pathogenicrs151340626GRCh37Chr X, 49850644: 49850644
8CLCN5CLCN5, ALU INS, EX11insertionPathogenicChr na, -1: -1
9CLCN5NM_000084.4(CLCN5): c.779G> T (p.Gly260Val)SNVPathogenicrs151340630GRCh37Chr X, 49850692: 49850692
10CLCN5CLCN5, IVS8DS, G-T, +1SNVPathogenicChr na, -1: -1
11OCRLNM_000276.3(OCRL): c.2299C> T (p.Gln767Ter)SNVPathogenicrs794727333GRCh37Chr X, 128722198: 128722198
12CLCN5NM_000084.4(CLCN5): c.100C> T (p.Arg34Ter)SNVPathogenicrs797044808GRCh38Chr X, 50070025: 50070025
13CLCN5NM_000084.4(CLCN5): c.836G> A (p.Trp279Ter)SNVPathogenicrs797044809GRCh38Chr X, 50086359: 50086359
14CLCN5NM_000084.4(CLCN5): c.1039C> T (p.Arg347Ter)SNVPathogenicrs797044810GRCh37Chr X, 49851219: 49851219
15CLCN5NM_000084.4(CLCN5): c.1399C> T (p.Arg467Ter)SNVPathogenicrs797044811GRCh38Chr X, 50088749: 50088749
16CLCN5NM_000084.4(CLCN5): c.1546C> T (p.Arg516Trp)SNVLikely pathogenicrs797044812GRCh38Chr X, 50090127: 50090127
17CLCN5NM_000084.4(CLCN5): c.1909C> T (p.Arg637Ter)SNVPathogenicrs797044813GRCh38Chr X, 50090490: 50090490
18CLCN5NM_000084.4(CLCN5): c.2152C> T (p.Arg718Ter)SNVPathogenicrs797044814GRCh37Chr X, 49856787: 49856787
19CLCN5NG_007159.3: g.(?_162979)_(164232_?)deldeletionPathogenicGRCh37Chr X, 49845251: 49846504
20CLCN5NM_001127899.3(CLCN5): c.2393_2415del23 (p.Val798Glyfs)deletionPathogenicrs797044815GRCh38Chr X, 50092161: 50092183
21CLCN5NC_000023.11: g.(?_49922616)_(50099235_?)deldeletionPathogenicGRCh38Chr X, 49922616: 50099235
22CLCN5NC_000023.11: g.(?_49922616)_(50099235_?)deldeletionPathogenicGRCh38Chr X, 49922616: 50099235
23CLCN5NC_000023.11: g.(?_49922616)_(50099235_?)deldeletionPathogenicGRCh38Chr X, 49922616: 50099235
24CLCN5undetermined variantPathogenicChr na, -1: -1
25OCRLNM_000276.3: c.2140_*2286deldeletionPathogenicChr na, -1: -1
26OCRLNM_000276.3: c.120_238deldeletionPathogenicChr na, -1: -1
27OCRLOCRL, ARG476TRPSNVPathogenicChr na, -1: -1
28OCRLOCRL, ILE526THRSNVPathogenicChr na, -1: -1
29OCRLOCRL, 2-BP DEL, 166TTdeletionPathogenicChr na, -1: -1
30CLCN5NM_000084.4(CLCN5): c.1020C> A (p.Asn340Lys)SNVPathogenicrs273585646GRCh37Chr X, 49851200: 49851200
31CLCN5NM_000084.4(CLCN5): c.1537G> A (p.Gly513Arg)SNVPathogenicrs273585647GRCh37Chr X, 49854775: 49854775
32CLCN5NM_000084.4(CLCN5): c.1637A> G (p.Lys546Arg)SNVPathogenicrs273585649GRCh37Chr X, 49854875: 49854875
33CLCN5NM_000084.4(CLCN5): c.1639T> G (p.Trp547Gly)SNVPathogenicrs273585650GRCh37Chr X, 49854877: 49854877
34CLCN5NM_000084.4(CLCN5): c.674T> C (p.Leu225Pro)SNVPathogenicrs273585645GRCh37Chr X, 49846455: 49846455
35CLCN5NM_000084.4(CLCN5): c.815A> G (p.Tyr272Cys)SNVPathogenicrs273585644GRCh37Chr X, 49850995: 49850995
36CLCN5NM_000084.4(CLCN5): c.834G> C (p.Leu278Phe)SNVPathogenicrs273585648GRCh37Chr X, 49851014: 49851014
37OCRLNM_000276.3(OCRL): c.2563delG (p.Val855Serfs)deletionPathogenicrs398123288GRCh37Chr X, 128723915: 128723915
38OCRLNM_000276.3(OCRL): c.2582-1G> ASNVPathogenicrs398123289GRCh37Chr X, 128724122: 128724122
39OCRLNM_000276.3(OCRL): c.909_910delAG (p.Gly304Phefs)deletionPathogenicrs398123290GRCh37Chr X, 128695240: 128695241

Expression for genes affiliated with Dent Disease

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Search GEO for disease gene expression data for Dent Disease.

Pathways for genes affiliated with Dent Disease

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Pathways related to Dent Disease according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.4INPP5E, OCRL
28.8CLCNKA, CLCNKB, SLC12A1, SLC12A3
3
Show member pathways
8.4CLCN1, CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB
4
Show member pathways
8.4CLCN1, CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB
5
Show member pathways
8.4CLCN1, CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB
6
Show member pathways
8.0CLCN1, CLCN4, CLCN5, CLCN7, SLC12A1, SLC12A3
7
Show member pathways
7.3CLCN1, CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB

GO Terms for genes affiliated with Dent Disease

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Cellular components related to Dent Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1clathrin-coated pitGO:000590510.1CUBN, LRP2, OCRL
2endosome membraneGO:001000810.0CLCN4, CLCN5, CUBN
3chloride channel complexGO:00347079.9CLCN1, CLCNKA, CLCNKB
4apical part of cellGO:00451779.6CLCN5, CUBN, LRP2
5lysosomal membraneGO:00057659.6CLCN5, CLCN7, CUBN, LRP2
6apical plasma membraneGO:00163249.1CUBN, LRP2, SLC12A1, SLC12A3
7integral component of plasma membraneGO:00058878.1CLCN1, CLCN4, CLCN5, CLCNKA, CLCNKB, SLC12A3
8plasma membraneGO:00058865.9CLCN1, CLCNKA, CLCNKB, CLDN16, CUBN, INPP5E

Biological processes related to Dent Disease according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1lipoprotein transportGO:004295310.4CUBN, LRP2
2vitamin D metabolic processGO:004235910.3CUBN, LRP2
3chloride transportGO:000682110.2CLCN1, CLCN4
4phosphatidylinositol dephosphorylationGO:004685610.1INPP5E, OCRL
5excretionGO:00075889.7CLCN5, CLCNKA, CLCNKB, CLDN16
6ion transportGO:00068119.4CLDN16, SLC12A1, SLC12A3
7regulation of anion transmembrane transportGO:19039598.9CLCN1, CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB
8ion transmembrane transportGO:00342208.2CLCN1, CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB
9transportGO:00068107.9CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB, SLC12A1
10chloride transmembrane transportGO:19024767.9CLCN1, CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB

Molecular functions related to Dent Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phosphatidylinositol-4,5-bisphosphate 5-phosphatase activityGO:00044399.9INPP5E, OCRL
2chloride channel activityGO:00052549.6CLCN4, CLCN5, CLCN7
3antiporter activityGO:00152979.2CLCN4, CLCN5, CLCN7
4chloride ion bindingGO:00314048.4CLCN1, CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB
5voltage-gated chloride channel activityGO:00052478.3CLCN1, CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB

Sources for Dent Disease

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet