MCID: DNT012
MIFTS: 50

Dental Caries

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Dental Caries

MalaCards integrated aliases for Dental Caries:

Name: Dental Caries 12 72 51 41 14 69
Dental Caries Extending into Pulp 12
Dental Caries of Smooth Surface 12
Dental Caries Pit and Fissure 12

Classifications:



External Ids:

Disease Ontology 12 DOID:216
ICD10 32 K02 K02.6 K02.9
MeSH 41 D003731
NCIt 46 C52593

Summaries for Dental Caries

MalaCards based summary : Dental Caries, also known as dental caries extending into pulp, is related to root caries and aplasia of lacrimal and salivary glands, and has symptoms including snoring and halitosis. An important gene associated with Dental Caries is CD79A (CD79a Molecule), and among its related pathways/superpathways is Salivary secretion. The drugs sodium fluoride and Salicylic acid have been mentioned in the context of this disorder. Affiliated tissues include salivary gland, testes and bone, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 72 Tooth decay, also known as dental caries or cavities, is a breakdown of teeth due to acids made by... more...

Related Diseases for Dental Caries

Diseases related to Dental Caries via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 97)
# Related Disease Score Top Affiliating Genes
1 root caries 33.0 CD79A DSPP LTF
2 aplasia of lacrimal and salivary glands 31.5 DSPP FGF10 LPO LTF
3 dental fluorosis 31.3 AMELX DSPP
4 dentin caries 11.7
5 enamel caries 11.3
6 periapical periodontitis 11.2
7 tricho-dento-osseous syndrome 1 11.1
8 flynn-aird syndrome 11.0
9 cockayne syndrome a 11.0
10 cutis laxa, autosomal recessive, type iia 11.0
11 insensitivity to pain, congenital, with anhidrosis 11.0
12 osteopetrosis, autosomal recessive 1 11.0
13 dominant dystrophic epidermolysis bullosa 11.0
14 odontoclasia 10.7
15 periodontitis 10.5
16 aging 10.4
17 parotitis 10.4 CD79A LTF
18 tooth disease 10.4
19 amelogenesis imperfecta, hypoplastic/hypomaturation, x-linked 2 10.4 AMELX TUFT1
20 tooth erosion 10.4 DSPP TUFT1
21 acute diarrhea 10.4 CD79A LTF
22 body mass index quantitative trait locus 11 10.4
23 body mass index quantitative trait locus 9 10.4
24 body mass index quantitative trait locus 8 10.4
25 body mass index quantitative trait locus 7 10.4
26 body mass index quantitative trait locus 12 10.4
27 body mass index quantitative trait locus 14 10.4
28 body mass index quantitative trait locus 18 10.4
29 amelogenesis imperfecta, type iiia 10.4 AMELX ENAM
30 amelogenesis imperfecta, type ie 10.4 AMELX TUFT1
31 dental pulp necrosis 10.4 AMELX DSPP
32 body mass index quantitative trait locus 4 10.4
33 body mass index quantitative trait locus 10 10.4
34 dental pulp calcification 10.3 DSPP ENAM
35 periodontal disease 10.3
36 body mass index quantitative trait locus 1 10.3
37 hypoplastic amelogenesis imperfecta 10.3 AMELX ENAM
38 tooth resorption 10.2 AMELX DSPP
39 hypercementosis 10.2 DSPP ENAM
40 dental pulp disease 10.2 AMELX DSPP
41 gingivitis 10.2
42 hypocalcified amelogenesis imperfecta 10.2 DSPP ENAM TUFT1
43 vaginal disease 10.1 CD79A DSPP
44 down syndrome 10.1
45 asthma 10.0
46 cerebral palsy 10.0
47 diabetes mellitus 10.0
48 cerebritis 10.0
49 chickenpox 10.0 CD79A LTF
50 alacrima, achalasia, and mental retardation syndrome 10.0

Comorbidity relations with Dental Caries via Phenotypic Disease Network (PDN): (show all 13)


Acute Apical Periodontitis Acute Cystitis
Acute Pericementitis Alzheimer Disease
Aortic Valve Disease 1 Deficiency Anemia
Familial Atrial Fibrillation Gingivitis
Heart Disease Ischemic Heart Disease
Periodontitis, Chronic Periodontosis
Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Dental Caries:



Diseases related to Dental Caries

Symptoms & Phenotypes for Dental Caries

UMLS symptoms related to Dental Caries:


snoring, halitosis

GenomeRNAi Phenotypes related to Dental Caries according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00381-A-1 9.56 LTF TAS1R2 TUFT1 CD79A
2 Decreased viability GR00381-A-3 9.56 CD79A LTF TAS1R2 TUFT1
3 Increased gamma-H2AX phosphorylation GR00053-A 9.28 CD79A CST1 DSPP HTN1 LTF MUC7

Drugs & Therapeutics for Dental Caries

Drugs for Dental Caries (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 246)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 sodium fluoride Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 7681-49-4
2
Salicylic acid Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 69-72-7 338
3
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
4
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
5
Methamphetamine Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1 537-46-2 10836
6
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 55-56-1 2713 9552079
7
Sorbitol Approved Phase 4,Phase 2,Phase 3 50-70-4 5780
8
Zinc Approved, Investigational Phase 4 7440-66-6 32051 23994
9
Zinc oxide Approved Phase 4 1314-13-2
10
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
11
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
12
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
13
Ethanol Approved Phase 4 64-17-5 702
14
Chloramphenicol Approved, Vet_approved Phase 4 56-75-7 5959 298
15
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
16
Thymol Approved Phase 4 89-83-8 6989
17
Chloramphenicol succinate Experimental Phase 4 3544-94-3
18 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
19 Fluorides Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
20 Cariostatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
21 Olaflur Phase 4
22 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
23 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
24 Anti-Infective Agents, Local Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
25 Fluorides, Topical Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
26 Listerine Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
27 Bone Density Conservation Agents Phase 4,Phase 3,Phase 2,Phase 1
28 Calcium, Dietary Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
29 Sodium fluoride topical preparation Phase 4,Phase 2
30 Antifungal Agents Phase 4
31 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
32 Keratolytic Agents Phase 4
33 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1
34 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
35 Central Nervous System Stimulants Phase 4,Phase 3,Phase 2,Phase 1
36 Dopamine Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Dopamine Uptake Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
38 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
39 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
40 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Chlorhexidine gluconate Phase 4,Phase 3,Phase 2,Phase 1
42 Disinfectants Phase 4,Phase 3,Phase 2,Phase 1
43 Cathartics Phase 4,Phase 2,Phase 3
44 Gastrointestinal Agents Phase 4,Phase 2,Phase 3
45 Laxatives Phase 4,Phase 2,Phase 3
46 Analgesics Phase 4,Phase 2
47 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
48 Anti-Anxiety Agents Phase 4
49 Central Nervous System Depressants Phase 4,Phase 1
50 Psychotropic Drugs Phase 4

Interventional clinical trials:

(show top 50) (show all 506)

# Name Status NCT ID Phase Drugs
1 Dental Caries Management by Risk Assessment: Identification and Treatment of Risk Factors Among (IDF) Personnel Unknown status NCT01142440 Phase 4
2 Elmex Gel Efficacy in Preventing White Spot Lesions Unknown status NCT00268138 Phase 4 elmex gel
3 Consumption Effect of Probiotic Products on Salivary Cariogenic Bacterial Counts in Preschool Children. Unknown status NCT02692625 Phase 4
4 Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2). Unknown status NCT01778699 Phase 4
5 Prevention of Dental Caries Lesions With Fluoride Varnish in Erupting First Permanent Molars Completed NCT02592278 Phase 4 Fluoride Varnish;Control Group
6 Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study Completed NCT00723515 Phase 4 sodium fluoride;sodium fluoride calcium fluoride
7 Impact of Fluoride Vanish Application in Dental Prevention for Elderly Completed NCT01038817 Phase 4 Duraphat
8 Preventive and Therapeutic Proximal Sealants Completed NCT02338180 Phase 4
9 Use of Fissure Sealants on Primary Molars Completed NCT01438866 Phase 4
10 The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions Completed NCT02953886 Phase 4
11 Fluoride Varnish For Childsmile Nursery School Attenders Completed NCT01674933 Phase 4 Duraphat® Fluoride Varnish
12 Impact of Maternal Xylitol Consumption on Mutans Sterptococci Completed NCT02036151 Phase 4 xylitol;fluoride varnish application
13 Fuji Type VII Sealant Versus Resin Based Sealant. A Clinical Trial Completed NCT02795728 Phase 4
14 Comparison of the Effect of Fluoride Remineralizer Gel and Foam Completed NCT02490592 Phase 4
15 Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients Completed NCT01768390 Phase 4
16 Postoperative Pulpal Complications in Posterior Resin Composite Restorations Without Glass-ionomer Cement Lining Completed NCT01567514 Phase 4
17 Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride Completed NCT01563172 Phase 4 Sodium fluoride / silica and carbopol, 0.5g;Sodium fluoride / silica and carbopol, 1.5g;Sodium fluoride / silica and carbopol, 1.5g
18 Enamel Remineralization Potential of Dentifrices in Situ Completed NCT01128946 Phase 4 NaF;SnF;NaMFP
19 MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study Completed NCT02424097 Phase 4 CPP-ACP 5% sodium fluoride varnish & 900ppm fluoride paste;1,100pm F-toothpaste and 0.5%NaF rinse
20 Interaction Between Chlorhexidine and Fluoride Completed NCT02935322 Phase 4 0.12 % chlorhexidine + 0.2 % NaF mouthrinse;0.2 % NaF mouthrinse;0.12% chlorhexidine
21 Bifidobacterium Lactis BB12 and Xylitol Delivered With a Novel Slow-release Pacifier Completed NCT00638677 Phase 4
22 Efficacy of Moderate Sedation for Dental Treatment of Young Children Completed NCT00902395 Phase 4 Midazolam;Midazolam, ketamine
23 Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing Completed NCT02921165 Phase 4 analgesic mouth rinses (dissolved Aspirin);Normal saline rinses.
24 Effects of Two Sugar Substituted Chewing Gums on Caries and Gingivitis Variables Completed NCT01578603 Phase 4
25 MI Varnish for the Prevention of White Spot Lesions Completed NCT03446690 Phase 4 MI Varnish
26 Treatment of Immature Permanent Teeth With Three Different Pulp Capping Materials With Partial Pulpotomy Completed NCT03426046 Phase 4 Pulp Capping Agents
27 Remineralisation of White Spot Lesions by Elmex® gelée in Post-orthodontic Patients Completed NCT01329731 Phase 4 elmex® gelée;negative control (placebo)
28 Antimicrobial Pulpotomy of Primary Molars Completed NCT01010451 Phase 4
29 Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study Completed NCT01601145 Phase 4
30 Music Distraction Strategy in Children Dental Care Completed NCT02489812 Phase 4
31 Oral Fluoride Bioavailability by the Consumption of Meals Prepared With Fluoridated Water or Salt Completed NCT02776280 Phase 4
32 Occlusal Caries Management in First Permanent Molars in Child Dental Care Recruiting NCT03315312 Phase 4 Fluoride Varnishes;Fissure Sealants
33 Cost-efficacy Between ART and Composite Resin Restorations in Primary Molars Recruiting NCT02562456 Phase 4
34 Treatment of Postorthodontic White Spot Lesions Recruiting NCT03217084 Phase 4 MI varnish GC;White varnish 3M
35 Effectiveness and Economic Evaluation of Glass Ionomer Material Using as Dental Sealant Recruiting NCT03034837 Phase 4 resin sealant;ART sealant
36 Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment Active, not recruiting NCT02447289 Phase 4 Intranasal ketamine;Oral ketamine;Intranasal midazolam;Oral midazolam
37 Cost-efficacy of Atraumatic Restorations (ART) Using Different Encapsulated Glass Ionomer Cement Active, not recruiting NCT02730000 Phase 4
38 Efficacy of Calcium Silicate Pulp-capping; a Randomized Controlled Clinical Trial Active, not recruiting NCT02201641 Phase 4
39 The Effects of Chlorhexidine/Thymol Varnish on Partial Denture Patient Withdrawn NCT02202304 Phase 4 Chlorhexidine/Thymol varnish
40 Three Measures for the Prevention of Carious Lesions in Preschool Children Unknown status NCT02341352 Phase 3 fluoride varnish
41 Fluoride Varnish in the Prevention of Dental Caries in Aboriginal and Non-aboriginal Children Unknown status NCT00435500 Phase 3 Fluoride varnish
42 Effect of Erythritol and Xylitol on Dental Caries Prevention in Children Unknown status NCT01062633 Phase 2, Phase 3
43 Preventing Early Childhood Caries in Indigenous Children: the Baby Teeth Talk Study Unknown status NCT02151916 Phase 3
44 Evaluation of Implants Placed Immediately or Delayed Into Extraction Sites Unknown status NCT00067392 Phase 3
45 Using Combination of Synthetic Bone Substitutes During Extractions Unknown status NCT01503593 Phase 3
46 Arresting Active Dental Caries in Preschool Children by Topical Fluorides Completed NCT02426619 Phase 2, Phase 3
47 Effectiveness of Fissure Sealant and Topical Fluoride Application in Preventing Dental Caries Completed NCT01446107 Phase 2, Phase 3
48 Consumption of Probiotics on Salivary Bacteria Causing Dental Caries Completed NCT02752594 Phase 2, Phase 3
49 Effect of Therapeutic Measures in Dental Caries Reduction in Children With Primary Dentition From Medellín City Completed NCT00475618 Phase 3
50 Effectiveness of SDF in Arresting Dental Caries in Preschool Children Completed NCT02385474 Phase 3 12% SDF;38% SDF

Search NIH Clinical Center for Dental Caries

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: dental caries

Genetic Tests for Dental Caries

Anatomical Context for Dental Caries

MalaCards organs/tissues related to Dental Caries:

38
Salivary Gland, Testes, Bone, Heart, Kidney, Colon, Neutrophil

Publications for Dental Caries

Articles related to Dental Caries:

(show top 50) (show all 750)
# Title Authors Year
1
The Associations of School Oral Health-Related Environments with Oral Health Behaviours and Dental Caries in Children. ( 29393138 )
2018
2
The Effect of Chemically Modified Tetracycline-3 on the Progression of Dental Caries in Rats. ( 29408826 )
2018
3
Oral health outcomes: the association of clinical and socio-dental indicators to evaluate dental caries in preschool children. ( 29412407 )
2018
4
Effect of inhaled medication on dental caries index in asthmatic children. ( 29402495 )
2018
5
Obesity and Dental Caries in Young Children in Plymouth, United Kingdom: A Spatial Analysis. ( 29380963 )
2018
6
Do Signs of Attention-Deficit/Hyperactivity Disorder Increase the Odds of Dental Caries? A Case-Control Study. ( 29393165 )
2018
7
Beyond Streptococcus mutans: clinical implications of the evolving dental caries aetiological paradigms and its associated microbiome. ( 29449651 )
2018
8
Inequalities in dental caries experience among 4-year-old New Zealand children. ( 29419880 )
2018
9
Dental caries in peoples of Xingu Indigenous Park, Brazil, 2007 and 2013. ( 29412349 )
2018
10
Redefining the Phenotype of Dental Caries. ( 29393149 )
2018
11
Dental caries: Research perspective. ( 29442078 )
2018
12
Mutans Streptococci and Dental Caries: A New Statistical Modeling Approach. ( 29393143 )
2018
13
Dental caries prevention strategies among children and adolescents with immigrantA - or low socioeconomic backgrounds- do they work? A systematic review. ( 29415706 )
2018
14
Relationship between parents' occupational characteristics and untreated dental caries in offspring: A population-based study of data from the Korean National Health and Nutrition Examination Survey, 2008-2015. ( 29392328 )
2018
15
Cost-effectiveness analysis of a school-based dental caries prevention program using fluoridated milk in Bangkok, Thailand. ( 29448929 )
2018
16
Type 2 diabetes as a risk indicator for dental caries in Korean adults: the 2011-2012 Korea national health and nutrition examination survey. ( 28872812 )
2017
17
Are people with an orofacial cleft at a higher risk of dental caries? A systematic review and meta-analysis. ( 28684841 )
2017
18
Prevalence of dental caries in overweight school going children of 12-15 years in and around Jaipur city, Rajasthan, India ( 29417789 )
2017
19
Relationship between Risk Behavior for Eating Disorders and Dental Caries and Dental Erosion. ( 29423431 )
2017
20
Assessment of Vitamin B12 and Its Correlation with Dental Caries and Gingival Diseases in 10- to 14-year-old Children: A Cross-sectional Study. ( 28890613 )
2017
21
Fluoride compounds in dental caries prophylaxis in children and adolescents a89 review of Polish literature ( 29417787 )
2017
22
The Lack of Association between FCN2 Gene Promoter Region Polymorphisms and Dental Caries in Polish Children. ( 28088794 )
2017
23
Relationship of salivary CD14 concentration with dental caries in young children. ( 28936284 )
2017
24
Long-term Hyperglycemia Naturally Induces Dental Caries But Not Periodontal Disease in Type-1 and Type-2 Diabetic Rodents. ( 28793985 )
2017
25
The impact of MUC5B gene on dental caries. ( 28944591 )
2017
26
Intricate Evaluation of Association between Dental Caries and Obesity among the Children in Al-Kharj City (Saudi Arabia). ( 28050981 )
2017
27
Second-generation Flagellin-rPAc Fusion Protein, KFD2-rPAc, Shows High Protective Efficacy against Dental Caries with Low Potential Side Effects. ( 28894188 )
2017
28
Effects of Caesalpinia sappan on pathogenic bacteria causing dental caries and gingivitis. ( 29332889 )
2017
29
Evaluation of the relationship between obesity, dental caries and periodontal disease in adolescents. ( 29380611 )
2017
30
Untreated Dental Caries Is Associated with Reports of Verbal Bullying in Children 8-10 Years Old. ( 28954260 )
2017
31
Fluoride mouthrinses for preventing dental caries in children and adolescents. ( 28944499 )
2017
32
The Influence of Sweet Taste Perception on Dietary Intake in Relation to Dental Caries and BMI in Saudi Arabian Schoolchildren. ( 28912812 )
2017
33
Association between socio-economic status and dental caries in elderly people in Sichuan Province, China: a cross-sectional study. ( 28947446 )
2017
34
Trends in dental caries rates over 45 years (1971-2016) among schoolchildren in FlorianA^polis, southern Brazil. ( 28880993 )
2017
35
Feeding frequency in infancy and dental caries in childhood: a prospective cohort study. ( 28868798 )
2017
36
Prevalence of Dental Caries and Traumatic Dental Injuries among 6- to 12-year-old Children in Bhopal City, India. ( 28890618 )
2017
37
Bayesian Analysis of the Association between Family-Level Factors and Siblings' Dental Caries. ( 28871287 )
2017
38
Oral Health-Promoting School Environments and Dental Caries in QuAcbec Children. ( 28869092 )
2017
39
The Role of Genetic Factors in the Outbreak Mechanism of Dental Caries. ( 28937897 )
2017
40
Tooth loss, periodontal disease, and dental caries may be associated with decreased oral health-related quality of life, but there is no evidence about the magnitude of this association. ( 28821339 )
2017
41
Effectiveness of water fluoridation in the prevention of dental caries across adult age groups. ( 28092105 )
2017
42
Assessment of dental caries, oral hygiene status, traumatic dental injuries and provision of basic oral health care among visually impaired children of Eastern Odisha. ( 28914238 )
2017
43
Hypomineralised second primary molars: prevalence, defect characteristics and relationship with dental caries in Melbourne preschool children. ( 28881480 )
2017
44
Occurrence of vancomycin-resistant Staphylococcus aureus in the oral cavity of patients with dental caries. ( 28889756 )
2017
45
Variants on chromosome 4q21 near PKD2 and SIBLINGs are associated with dental caries. ( 28100911 )
2017
46
Effect of Silver Nanoparticle-Added Pit and Fissure Sealant in the Prevention of Dental Caries in Children. ( 28052214 )
2017
47
Association between Low blood lead levels and increased risk of dental caries in children: a cross-sectional study. ( 28086936 )
2017
48
Low sugar nutrition policies and dental caries: A study of primary schools in South Auckland. ( 28073166 )
2017
49
Risk factors and prevalence of dental fluorosis and dental caries in school children of North India. ( 28025807 )
2017
50
Parents' online discussions about children's dental caries: A critical content analysis. ( 28910248 )
2017

Variations for Dental Caries

Expression for Dental Caries

Search GEO for disease gene expression data for Dental Caries.

Pathways for Dental Caries

Pathways related to Dental Caries according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.38 CST1 HTN1 LPO MUC7 PRH1 PRH2

GO Terms for Dental Caries

Cellular components related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 CA6 CST1 FGF10 LPO LTF LYZL2
2 proteinaceous extracellular matrix GO:0005578 9.56 AMELX DSPP ENAM TFIP11
3 extracellular region GO:0005576 9.47 AMELX CA6 CST1 DSPP ENAM FGF10
4 other organism cell membrane GO:0044218 8.96 LTF MUC7

Biological processes related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.62 HTN1 LPO LTF STATH
2 ossification GO:0001503 9.54 DSPP LTF STATH
3 odontogenesis of dentin-containing tooth GO:0042475 9.43 AMELX ENAM FGF10
4 negative regulation of cysteine-type endopeptidase activity GO:2000117 9.4 CST1 LTF
5 killing of cells of other organism GO:0031640 9.33 HTN1 LTF MUC7
6 detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 9.26 CA6 CST1 LPO TAS2R38
7 biomineral tissue development GO:0031214 9.17 AMELX DSPP ENAM HTN1 STATH TFIP11

Molecular functions related to Dental Caries according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydroxyapatite binding GO:0046848 8.96 AMELX STATH
2 structural constituent of tooth enamel GO:0030345 8.92 AMELX ENAM STATH TUFT1

Sources for Dental Caries

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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