MCID: DNT013
MIFTS: 27

Dental Enamel Hypoplasia malady

Summaries for Dental Enamel Hypoplasia

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32MalaCards
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MalaCards: Dental Enamel Hypoplasia, also known as enamel hypoplasia, is related to amelogenesis imperfecta and deafness enamel hypoplasia nail defects. An important gene associated with Dental Enamel Hypoplasia is DLX3 (distal-less homeobox 3). The compounds fluoride and phenylalanine have been mentioned in the context of this disorder. Affiliated tissues include testes, and related mouse phenotype integument.

Aliases & Classifications for Dental Enamel Hypoplasia

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8Disease Ontology, 10DISEASES, 60UMLS, 44Novoseek, 39NCIt, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

dental enamel hypoplasia 8 10 60
enamel hypoplasia 8 44


External Ids:

Disease Ontology8 DOID:693
NCIt39 C34529
SNOMED-CT56 196277000, 26597004
MeSH34 D003744

Related Diseases for Dental Enamel Hypoplasia

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Dental Enamel Hypoplasia:



Diseases related to dental enamel hypoplasia

Clinical Features for Dental Enamel Hypoplasia

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Drugs & Therapeutics for Dental Enamel Hypoplasia

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Dental Enamel Hypoplasia

Drug clinical trials:

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Search NIH Clinical Center for Dental Enamel Hypoplasia

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Genetic Tests for Dental Enamel Hypoplasia

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Anatomical Context for Dental Enamel Hypoplasia

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32MalaCards
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MalaCards organs/tissues related to Dental Enamel Hypoplasia:

32
Testes

Animal Models for Dental Enamel Hypoplasia or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Dental Enamel Hypoplasia:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.4TDO2, MSX2, GJA1, DLX3, NF1, COL17A1

Publications for Dental Enamel Hypoplasia

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50PubMed
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Articles related to Dental Enamel Hypoplasia:

(show all 11)
idTitleAuthorsYear
1
Patterns in dental enamel hypoplasia by sex and age at death in two archaeological populations. (18990363)
2009
2
NF1 microduplication first clinical report: association with mild mental retardation, early onset of baldness and dental enamel hypoplasia? (18183042)
2008
3
Early childhood stress and adult age mortality--a study of dental enamel hypoplasia in the medieval Danish village of Tirup. (16897774)
2007
4
Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region. (17537244)
2007
5
Amelogenesis imperfecta: diagnosis and resolution of a case with hypoplasia and hypocalcification of enamel, dental agenesis, and skeletal open bite. (12066657)
2001
6
A laboratory assessment of enamel hypoplasia of teeth with varying severities of dental fluorosis. (10447822)
1999
7
Dental enamel hypoplasia apropos of a case]. (8620979)
1996
8
Hypoplastic area method for analyzing dental enamel hypoplasia. (8599384)
1995
9
Frequency and chronological distribution of dental enamel hypoplasia in enslaved African Americans: a test of the weaning hypothesis. (7864059)
1994
10
Incidence and patterning of dental enamel hypoplasia among the Neandertals. (2665513)
1989
11
Prevalence and possible etiology of dental enamel hypoplasia. (637120)
1978

Genetic Variations for Dental Enamel Hypoplasia

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Expression for genes affiliated with Dental Enamel Hypoplasia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dental Enamel Hypoplasia

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Pathways for genes affiliated with Dental Enamel Hypoplasia

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Compounds for genes affiliated with Dental Enamel Hypoplasia

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44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB
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Compounds related to Dental Enamel Hypoplasia according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1fluoride449.6NF1, DSPP
2phenylalanine449.4TDO2, GJA1, COL17A1
3calcium44 49 11 2410.7COL17A1, PDLIM1, DSPP, NF1, GJA1, MSX2

GO Terms for genes affiliated with Dental Enamel Hypoplasia

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16Gene Ontology
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Biological processes related to Dental Enamel Hypoplasia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1biomineral tissue developmentGO:0312149.5DSPP, ODAM
2osteoblast differentiationGO:0016499.1MSX2, GJA1, NF1

Products for genes affiliated with Dental Enamel Hypoplasia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Dental Enamel Hypoplasia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet