MCID: DNT013
MIFTS: 28

Dental Enamel Hypoplasia malady

Oral diseases category
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Summaries for Dental Enamel Hypoplasia

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33MalaCards
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MalaCards: Dental Enamel Hypoplasia, also known as enamel hypoplasia, is related to amelogenesis imperfecta and deafness enamel hypoplasia nail defects. An important gene associated with Dental Enamel Hypoplasia is DUSP23 (dual specificity phosphatase 23). The compounds halothane and doxycycline have been mentioned in the context of this disorder. Affiliated tissues include testes.

Aliases & Classifications for Dental Enamel Hypoplasia

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8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 40NCIt, 58SNOMED-CT, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Oral diseases


Aliases & Descriptions:

dental enamel hypoplasia 8 10 62
enamel hypoplasia 8 45


External Ids:

Disease Ontology8 DOID:693
NCIt40 C34529
SNOMED-CT58 26597004, 196277000
MeSH35 D003744

Related Diseases for Dental Enamel Hypoplasia

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Dental Enamel Hypoplasia:



Diseases related to dental enamel hypoplasia

Symptoms for Dental Enamel Hypoplasia

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Drugs & Therapeutics for Dental Enamel Hypoplasia

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42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

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Search NIH Clinical Center for Dental Enamel Hypoplasia

Genetic Tests for Dental Enamel Hypoplasia

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Anatomical Context for Dental Enamel Hypoplasia

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33MalaCards
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MalaCards organs/tissues related to Dental Enamel Hypoplasia:

33
Testes

Animal Models for Dental Enamel Hypoplasia or affiliated genes

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Publications for Dental Enamel Hypoplasia

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52PubMed
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Articles related to Dental Enamel Hypoplasia:

idTitleAuthorsYear
1
Patterns in dental enamel hypoplasia by sex and age at death in two archaeological populations. (18990363)
2009
2
NF1 microduplication first clinical report: association with mild mental retardation, early onset of baldness and dental enamel hypoplasia? (18183042)
2008
3
Early childhood stress and adult age mortality--a study of dental enamel hypoplasia in the medieval Danish village of Tirup. (16897774)
2007
4
Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region. (17537244)
2007
5
Dental enamel hypoplasia apropos of a case]. (8620979)
1996
6
Hypoplastic area method for analyzing dental enamel hypoplasia. (8599384)
1995
7
Frequency and chronological distribution of dental enamel hypoplasia in enslaved African Americans: a test of the weaning hypothesis. (7864059)
1994
8
Incidence and patterning of dental enamel hypoplasia among the Neandertals. (2665513)
1989
9
Prevalence and possible etiology of dental enamel hypoplasia. (637120)
1978

Variations for Dental Enamel Hypoplasia

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Expression for genes affiliated with Dental Enamel Hypoplasia

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dental Enamel Hypoplasia

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Pathways for genes affiliated with Dental Enamel Hypoplasia

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Compounds for genes affiliated with Dental Enamel Hypoplasia

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45Novoseek, 51PharmGKB, 29IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Dental Enamel Hypoplasia according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1halothane45 51 29 1112.5GJA1, DSPP
2doxycycline45 1110.4DSPP, GJA1
3fluoride459.4NF1, DSPP
4paraffin459.0NF1, GJA1, DSPP
5alanine458.6NF1, GJA1, DSPP
6calcium45 51 24 1111.4NF1, GJA1, PDLIM1, DSPP

GO Terms for genes affiliated with Dental Enamel Hypoplasia

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16Gene Ontology
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Biological processes related to Dental Enamel Hypoplasia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to hypoxiaGO:0016669.3NF1, PDLIM1
2heart developmentGO:0075079.1NF1, GJA1

Products for genes affiliated with Dental Enamel Hypoplasia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Dental Enamel Hypoplasia

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet