MCID: DNT013
MIFTS: 27

Dental Enamel Hypoplasia malady

Category: Oral diseases

Aliases & Classifications for Dental Enamel Hypoplasia

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Aliases & Descriptions for Dental Enamel Hypoplasia:

Name: Dental Enamel Hypoplasia 11 13 25 37
 
Enamel Hypoplasia 11 48

Classifications:



External Ids:

Disease Ontology11 DOID:693
MeSH37 D003744
NCIt43 C34529

Summaries for Dental Enamel Hypoplasia

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MalaCards based summary: Dental Enamel Hypoplasia, also known as enamel hypoplasia, is related to deafness enamel hypoplasia nail defects and alaninuria with microcephaly, dwarfism, enamel hypoplasia, and diabetes mellitus. An important gene associated with Dental Enamel Hypoplasia is AMELX (Amelogenin, X-Linked). Affiliated tissues include testes, and related mouse phenotypes are skeleton and craniofacial.

Related Diseases for Dental Enamel Hypoplasia

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Graphical network of the top 20 diseases related to Dental Enamel Hypoplasia:



Diseases related to dental enamel hypoplasia

Symptoms for Dental Enamel Hypoplasia

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Drugs & Therapeutics for Dental Enamel Hypoplasia

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Drugs for Dental Enamel Hypoplasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Salicylic acid16569-72-7338
Synonyms:
105910_ALDRICH
105910_SIAL
2 Hydroxybenzoic Acid
2-Carboxyphenol
2-Hydroxybenzenecarboxylate
2-Hydroxybenzenecarboxylic acid
2-Hydroxybenzoate
2-Hydroxybenzoic acid
2-hydroxy(1-14c)benzoic acid
247588_SIAL
27301_SIAL
69-72-7
7681-06-3
8052-31-1
84210_FLUKA
84210_SIAL
AB1002436
AC1L190M
AC1Q1HCK
AC1Q72IF
AI3-02407
AKOS000118979
ALPHA/BETA HYDROXY ACIDS (SALICYLIC ACID) (SEE ALPHA/BETA HYDROXY ACIDS)
AR-1E2203
ATA fraction 10, ammonium salt
Acid, 2-Hydroxybenzoic
Acid, Salicylic
Acid, o-Hydroxybenzoic
Acid, ortho-Hydroxybenzoic
Acido o-idrossibenzoico
Acido o-idrossibenzoico [Italian]
Acido salicilico
Acido salicilico [Italian]
Acidum salicylicum
Advanced Pain Relief Callus Removers
Advanced Pain Relief Corn Removers
Advanced pain relief callus removers
Advanced pain relief corn removers
Akurza Cream
Akurza Lotion
Alpha/Beta Hydroxy Acids (Glycolic Acid, Salicylic Acid)
BENZOIC ACID,2-HYDROXY SALICYLIC ACID
BIDD:ER0602
BRN 0774890
Benzoic acid, 2-hydroxy- (9CI)
C00805
CCRIS 6714
CHEBI:16914
CHEMBL424
CID338
CMC_13852
Caswell No. 731
Clear away Wart Remover
Clear away wart remover
Compound W
Compound w
D00097
D020156
DB00936
DHS Sal Shampoo
DivK1c_000301
Domerine
Dr. Scholl'S Callus Removers
Dr. Scholl'S Corn Removers
Dr. Scholl'S Wart Remover Kit
Dr. Scholl's callus removers
Dr. Scholl's corn removers
Dr. Scholl's wart remover kit
DuoPlant Gel
Duofil Wart Remover
Duofil wart remover
Duofilm
Duoplant
E9A559BE-383B-4F83-BC02-3031D03D558A
EINECS 200-712-3
EPA Pesticide Chemical Code 076602
Freezone
H0206
HSDB 672
Hydrisalic Gel
I04-0192
IDI1_000301
InChI=1/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10
Ionil
Ionil Plus
Ionil plus
Ionil-Plus
 
K 537
K 557
KBio1_000301
KBio2_001428
KBio2_003996
KBio2_006564
KBioSS_001428
Keralyt
Kyselina 2-hydroxybenzoova
Kyselina 2-hydroxybenzoova [Czech]
Kyselina salicylova
Kyselina salicylova [Czech]
LS-2169
MLS000069653
Mediplast pads
MolPort-001-769-476
NCGC00159447-02
NCGC00159447-04
NINDS_000301
NSC 180
NSC180
NSC629474
O-Carboxyphenol
O-Hydroxybenzoate
O-Hydroxybenzoic acid
O-carboxyphenol
O-hydroxybenzoic acid
Occlusal
Oprea1_040343
Orthohydroxybenzoic acid
P&S Shampoo
Phenol-2-carboxylate
Phenol-2-carboxylic acid
Propa pH Peel-Off Acne Mask
Psoriacid-S-Stift
Psoriacid-S-stift
Retarder SAX
Retarder W
Rutranex
S5922_SIGMA
S7401_SIGMA
S8519_SIGMA
SALICYLIC ACID (SEE ALSO ALPHA HYDROXY ACIDS)
SALICYLIC ACID, ACS
SAX
SBB052826
SGCUT00012
SMP2_000145
SMR000059163
STK258681
Salex Cream
Salex Lotion
Salicyclic acid
Salicylate
Salicylic acid
Salicylic acid & Sulfur Soap
Salicylic acid (6CI,8CI)
Salicylic acid (JP15/USP)
Salicylic acid (TN)
Salicylic acid Soap
Salicylic acid [USAN:JAN]
Salicylic acid collodion
Salicylic acid soap
Salicylic acid, tech
Salicylic acid, tech.
Salicylic acid-ring-UL-14C
Saligel
Salonil
Sebucare
Sebulex
Spectrum_000948
Stri-Dex
Trans-Ver-Sal
UNII-O414PZ4LPZ
UPCMLD-DP126
UPCMLD-DP126:001
Verrugon
W398500_ALDRICH
WLN: QVR BQ
bmse000252
o Hydroxybenzoic Acid
o-Carboxyphenol
o-hydroxybenzoic acid
ortho Hydroxybenzoic Acid
ortho-Hydroxybenzoic Acid
phenol derivative, 7
salicylate
salicylic acid
to_000004

Interventional clinical trials:

idNameStatusNCT IDPhase
1Sealants in Molars Affected by Molar-Incisor HypomineralizationCompletedNCT02794116
2Restorative Treatment in First Molars Affected by Molar-Incisor HypomineralizationCompletedNCT02717286
3Comparison of Intraosseous Anaesthesia Using a Computerized System (QuickSleeper) to Conventional AnesthesiaRecruitingNCT02084433
4Amelogenesis ImperfectaRecruitingNCT01746121

Search NIH Clinical Center for Dental Enamel Hypoplasia


Cochrane evidence based reviews: dental enamel hypoplasia

Genetic Tests for Dental Enamel Hypoplasia

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Genetic tests related to Dental Enamel Hypoplasia:

id Genetic test Affiliating Genes
1 Hypoplasia of Dental Enamel25

Anatomical Context for Dental Enamel Hypoplasia

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MalaCards organs/tissues related to Dental Enamel Hypoplasia:

34
Testes

Animal Models for Dental Enamel Hypoplasia or affiliated genes

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MGI Mouse Phenotypes related to Dental Enamel Hypoplasia:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.1AMBN, AMELY, ENAM, FAM20A, NF1
2MP:00053827.9AMBN, AMELY, ENAM, FAM20A, MMP20, NF1
3MP:00053786.8AMBN, AMELY, DLX3, ENAM, FAM20A, MMP20

Publications for Dental Enamel Hypoplasia

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Articles related to Dental Enamel Hypoplasia:

idTitleAuthorsYear
1
The possible correlation between dental enamel hypoplasia and a historic natural disaster in the Roman population of Herculaneum (79 AD - central Italy). (24620565)
2013
2
Patterns in dental enamel hypoplasia by sex and age at death in two archaeological populations. (18990363)
2009
3
NF1 microduplication first clinical report: association with mild mental retardation, early onset of baldness and dental enamel hypoplasia? (18183042)
2008
4
Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region. (17537244)
2007
5
Early childhood stress and adult age mortality--a study of dental enamel hypoplasia in the medieval Danish village of Tirup. (16897774)
2007
6
Dental enamel hypoplasia apropos of a case]. (8620979)
1996
7
Hypoplastic area method for analyzing dental enamel hypoplasia. (8599384)
1995
8
Frequency and chronological distribution of dental enamel hypoplasia in enslaved African Americans: a test of the weaning hypothesis. (7864059)
1994
9
Incidence and patterning of dental enamel hypoplasia among the Neandertals. (2665513)
1989
10
Prevalence and possible etiology of dental enamel hypoplasia. (637120)
1978

Variations for Dental Enamel Hypoplasia

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Expression for genes affiliated with Dental Enamel Hypoplasia

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Search GEO for disease gene expression data for Dental Enamel Hypoplasia.

Pathways for genes affiliated with Dental Enamel Hypoplasia

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GO Terms for genes affiliated with Dental Enamel Hypoplasia

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Cellular components related to Dental Enamel Hypoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1proteinaceous extracellular matrixGO:00055788.7AMBN, AMELX, AMELY, ENAM, MMP20

Biological processes related to Dental Enamel Hypoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1amelogenesisGO:00971869.9ENAM, MMP20
2enamel mineralizationGO:00701669.9AMELX, FAM20A
3odontogenesis of dentin-containing toothGO:00424758.5AMBN, AMELX, DLX3, ENAM
4biomineral tissue developmentGO:00312148.1AMBN, AMELX, AMELY, ENAM, FAM20A, FAM83H

Molecular functions related to Dental Enamel Hypoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of tooth enamelGO:00303459.1AMBN, AMELX, AMELY, ENAM

Sources for Dental Enamel Hypoplasia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet