MCID: DNT013
MIFTS: 28

Dental Enamel Hypoplasia malady

Oral diseases category

Summaries for Dental Enamel Hypoplasia

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34MalaCards
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MalaCards: Dental Enamel Hypoplasia, also known as enamel hypoplasia, is related to amelogenesis imperfecta and deafness enamel hypoplasia nail defects. An important gene associated with Dental Enamel Hypoplasia is DUSP23 (dual specificity phosphatase 23). The compounds halothane and doxycycline have been mentioned in the context of this disorder. Affiliated tissues include testes.

Aliases & Classifications for Dental Enamel Hypoplasia

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Sources:
9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 41NCIt, 59SNOMED-CT, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Oral diseases


Aliases & Descriptions:

dental enamel hypoplasia 9 11 63
enamel hypoplasia 9 46


External Ids:

Disease Ontology9 DOID:693
NCIt41 C34529
SNOMED-CT59 26597004, 196277000
MeSH36 D003744

Related Diseases for Dental Enamel Hypoplasia

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Dental Enamel Hypoplasia:



Diseases related to dental enamel hypoplasia

Symptoms for Dental Enamel Hypoplasia

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Drugs & Therapeutics for Dental Enamel Hypoplasia

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Dental Enamel Hypoplasia

Search CenterWatch for Dental Enamel Hypoplasia

Genetic Tests for Dental Enamel Hypoplasia

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Anatomical Context for Dental Enamel Hypoplasia

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34MalaCards
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MalaCards organs/tissues related to Dental Enamel Hypoplasia:

34
Testes

Animal Models for Dental Enamel Hypoplasia or affiliated genes

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Publications for Dental Enamel Hypoplasia

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53PubMed
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Articles related to Dental Enamel Hypoplasia:

idTitleAuthorsYear
1
Patterns in dental enamel hypoplasia by sex and age at death in two archaeological populations. (18990363)
2009
2
NF1 microduplication first clinical report: association with mild mental retardation, early onset of baldness and dental enamel hypoplasia? (18183042)
2008
3
Early childhood stress and adult age mortality--a study of dental enamel hypoplasia in the medieval Danish village of Tirup. (16897774)
2007
4
Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region. (17537244)
2007
5
Dental enamel hypoplasia apropos of a case]. (8620979)
1996
6
Hypoplastic area method for analyzing dental enamel hypoplasia. (8599384)
1995
7
Frequency and chronological distribution of dental enamel hypoplasia in enslaved African Americans: a test of the weaning hypothesis. (7864059)
1994
8
Incidence and patterning of dental enamel hypoplasia among the Neandertals. (2665513)
1989
9
Prevalence and possible etiology of dental enamel hypoplasia. (637120)
1978

Variations for Dental Enamel Hypoplasia

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Expression for genes affiliated with Dental Enamel Hypoplasia

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dental Enamel Hypoplasia

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Pathways for genes affiliated with Dental Enamel Hypoplasia

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Compounds for genes affiliated with Dental Enamel Hypoplasia

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46Novoseek, 52PharmGKB, 30IUPHAR, 12DrugBank, 25HMDB
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Compounds related to Dental Enamel Hypoplasia according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1halothane46 52 30 1212.5GJA1, DSPP
2doxycycline46 1210.4DSPP, GJA1
3fluoride469.4NF1, DSPP
4paraffin469.0NF1, GJA1, DSPP
5alanine468.6NF1, GJA1, DSPP
6calcium46 52 25 1211.4NF1, GJA1, PDLIM1, DSPP

GO Terms for genes affiliated with Dental Enamel Hypoplasia

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17Gene Ontology
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Biological processes related to Dental Enamel Hypoplasia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to hypoxiaGO:0016669.3NF1, PDLIM1
2heart developmentGO:0075079.1NF1, GJA1

Products for genes affiliated with Dental Enamel Hypoplasia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Dental Enamel Hypoplasia

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet