Aliases & Classifications for Dental Pulp Disease

Aliases & Descriptions for Dental Pulp Disease:

Name: Dental Pulp Disease 12 14
Dental Pulp Diseases 42 69
Disorder of Pulp of Tooth 12
Dental Pulp Disorder 12
Pulp Disorder 12


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Disease Ontology 12 DOID:5330
MeSH 42 D003788
NCIt 47 C34530
SNOMED-CT 64 57203004
UMLS 69 C0011405

Summaries for Dental Pulp Disease

MalaCards based summary : Dental Pulp Disease, also known as dental pulp diseases, is related to cutaneous porphyria and febrile seizures, familial, 10, and has symptoms including toothache An important gene associated with Dental Pulp Disease is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Toll Comparative Pathway and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Dopamine and Epinephrine have been mentioned in the context of this disorder.

Related Diseases for Dental Pulp Disease

Diseases related to Dental Pulp Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
id Related Disease Score Top Affiliating Genes
1 cutaneous porphyria 10.2 NPS TRPV1
2 febrile seizures, familial, 10 10.2 NPS TAC1
3 leber congenital amaurosis 12 10.2 NPS TAC1
4 intussusception 10.2 IL1B TNF
5 tau syndrome 10.2 IL1B TNF
6 stocco dos santos syndrome 10.2 IL1B TNF
7 bulbomembranous urethral cancer 10.2 DSPP IL1B SASS6
8 hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 10.2 IL1B TNF
9 boutonneuse fever 10.2 NPS TAC1
10 twin-to-twin transfusion syndrome 10.2 IL1B TNF
11 febrile seizures, familial, 3b 10.2 SCN11A TRPV1
12 testicular leydig cell tumor 10.1 IL1B TAC1 TRPV1
13 granuloma annulare 10.1 DSPP IL1B
14 warthin tumor 10.1 IL1B TNF
15 eyelid neoplasm 10.1 NPS TAC1 TRPV1
16 placenta accreta 10.1 NPS TAC1
17 anal paget's disease 10.1 IL1B TNF
18 splenic artery aneurysm 10.1 IL1B TNF TRPV1
19 basal cell carcinoma 10.1 AMELY DSPP
20 personality disorder 10.1 NPS TAC1 TRPV1
21 peroneal neuropathy 10.1 IL1B TNF TRPV1
22 tuberculous peritonitis 10.1 TAC1 TNF TRPV1
23 cataract 10.1 IL1B TNF
24 neovascular glaucoma 10.1 TAC1 TNF TRPV1
25 body dysmorphic disorder 10.1 IL1B TNF TRPV1
26 central nervous system lymphoma 10.1 IL1B TAC1 TNF
27 childhood malignant hemangiopericytoma 10.1 IL1B TNF TRPV1
28 bipolar i disorder 10.1 IL1B TNF
29 spontaneous ocular nystagmus 10.1 IL1B TAC1 TNF
30 acute chest syndrome 10.0 IL1B TAC1 TNF
31 hepatic encephalopathy 10.0 IL1B TNF
32 acquired thrombocytopenia 10.0 DSPP IL1B TNF TRPV1
33 tinea capitis 10.0 IL1B TAC1 TNF TRPV1
34 uterine ligament clear cell adenocarcinoma 10.0 IL1B TAC1 TNF TRPV1
35 acquired polycythemia 10.0 NPS TAC1 TNF TRPV1
36 generalized epilepsy with febrile seizures plus 9.9 IL1B SCN11A TAC1 TRPV1
37 substance-induced psychosis 9.9 IL1B NPS TAC1 TNF
38 fungal gastritis 9.9 AMELY DSPP IL1B TNF
39 microcephaly 13, primary, autosomal recessive 9.8 NPS TAC1 TNF
40 accommodative spasm 9.7 AMELY DSPP LRRC7 SASS6 SCN11A
41 childhood endodermal sinus tumor 8.4 AMELY ASH1L DSPP ECSIT IL1B LRRC7

Graphical network of the top 20 diseases related to Dental Pulp Disease:

Diseases related to Dental Pulp Disease

Symptoms & Phenotypes for Dental Pulp Disease

UMLS symptoms related to Dental Pulp Disease:


Drugs & Therapeutics for Dental Pulp Disease

Drugs for Dental Pulp Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 182)
id Name Status Phase Clinical Trials Cas Number PubChem Id
Dopamine Approved Phase 4,Phase 2 51-61-6, 62-31-7 681
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 51-43-4 5816
Ibuprofen Approved Phase 4,Phase 2 15687-27-1 3672
Ketoprofen Approved, Vet_approved Phase 4 22071-15-4 3825
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2 137-58-6 3676
Methamphetamine Approved, Illicit Phase 4,Phase 2 537-46-2 10836
Tramadol Approved, Investigational Phase 4,Phase 1,Phase 2 27203-92-5 33741
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
12 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1
13 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
14 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
15 Antibiotics, Antitubercular Phase 4,Phase 1,Early Phase 1
16 Bone Density Conservation Agents Phase 4,Phase 2,Phase 3,Phase 1
17 Antitubercular Agents Phase 4,Phase 1,Early Phase 1
18 Calcium, Dietary Phase 4,Phase 2,Phase 3,Phase 1
Bismuth Phase 4,Phase 2,Phase 3 7440-69-9 16682734 105143
20 Prednisolone acetate Phase 4,Phase 3
21 Analgesics Phase 4,Phase 2,Phase 3,Phase 1
22 glucocorticoids Phase 4,Phase 3
23 Mydriatics Phase 4,Phase 3,Phase 2
24 Adrenergic Agents Phase 4,Phase 3,Phase 2
25 Narcotics Phase 4,Phase 2,Phase 1
26 Adrenergic Agonists Phase 4,Phase 3,Phase 2
27 Gastrointestinal Agents Phase 4,Phase 3
28 Sodium Channel Blockers Phase 4,Phase 3,Phase 2
29 Neuroprotective Agents Phase 4,Phase 3
30 Adrenergic alpha-Agonists Phase 4,Phase 3,Phase 2
31 Adrenergic beta-Agonists Phase 4,Phase 3,Phase 2
32 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
33 Cyclooxygenase Inhibitors Phase 4,Phase 2,Phase 3,Phase 1
34 Neurotransmitter Uptake Inhibitors Phase 4,Phase 2
35 Thioctic Acid Phase 4
36 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3,Phase 1
37 Trace Elements Phase 4
38 Analgesics, Opioid Phase 4,Phase 2,Phase 1
39 Hormone Antagonists Phase 4,Phase 3
40 Dexketoprofen trometamol Phase 4
41 Hormones Phase 4,Phase 3
42 Diuretics, Potassium Sparing Phase 4,Phase 3,Phase 2
43 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
44 Anesthetics, Local Phase 4,Phase 3,Phase 2
45 Dopamine Agents Phase 4,Phase 2
46 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3
47 Vasoconstrictor Agents Phase 4,Phase 3,Phase 2
48 Dopamine Uptake Inhibitors Phase 4,Phase 2
49 Vitamin B Complex Phase 4
50 Epinephryl borate Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 175)
id Name Status NCT ID Phase
1 Success Rate Evaluation of Miniature Pulpotomy With MTA in Primary Molars Unknown status NCT02286648 Phase 4
2 Postoperative Pain in Single-visit and Multiple-visit Retreatment Cases Completed NCT03042377 Phase 4
3 Efficacy Study of Articaine Versus Lidocaine as Supplemental Infiltration in Inflamed Molars Completed NCT01496846 Phase 4
4 Anesthetic Efficacy of Articaine and Lidocaine in Lower Molars With Irreversible Pulpits Completed NCT01912755 Phase 4
5 Dexketoprofen Trometamol in Postoperative Endodontic Pain Completed NCT02086097 Phase 4
6 Oral Glucocorticoids Effect on Post Endodontic Pain Completed NCT02819648 Phase 4
7 Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis Completed NCT02110966 Phase 4
8 Anesthetic Efficacy in Irreversible Pulpitis Completed NCT02054767 Phase 4
9 Prefabricated Endodontic Posts: Glass Fiber Versus Titanium - A Randomized Controlled Pilot- Trial Completed NCT01520766 Phase 4
10 Comparison of Two Dental Techniques Used to Treat Teeth Which Have Become Infected or Painful Following Trauma Completed NCT01817413 Phase 4
11 Postoperative Alpha Lipoic Acid in the Carpal Tunnel Syndrome: a Randomized Controlled Trial. Completed NCT01895621 Phase 4
12 Effectiveness of Trapeziometacarpal Splint Recruiting NCT02635932 Phase 4
13 Efficacy of Calcium Silicate Pulp-capping; a Randomized Controlled Clinical Trial Active, not recruiting NCT02201641 Phase 4
14 Success and Color Stability of MTA Pulpotomized Primary Molars: an RCT Enrolling by invitation NCT02702505 Phase 4
15 Human Pulpal Response After Pulp Capping With Four Different Agents Completed NCT01468480 Phase 2, Phase 3
16 Partial Pulpotomy on Caries Free Human Teeth Completed NCT01420718 Phase 2, Phase 3
17 4% Articaine and 2% Lidocaine by Intraligamentary Technique in Irreversible Pulpitis Completed NCT02807298 Phase 3
18 Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars Completed NCT03117491 Phase 3
19 Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis Completed NCT02226913 Phase 3
20 Assessment of a New Apexification Method for Patients Presenting a Non Vital Immature Tooth Completed NCT00472173 Phase 3
21 Use of Mineral Trioxide Aggregate in the Treatment of Traumatized Teeth Completed NCT02625298 Phase 2, Phase 3
22 Healozone Study to Evaluate the Safety and Efficacy of the Use of Ozone for Management of Dental Caries Completed NCT00495495 Phase 2, Phase 3
23 Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth Recruiting NCT02492841 Phase 2, Phase 3
24 Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success Recruiting NCT03174860 Phase 2, Phase 3
25 Clinical Comparison of Endodontically Treated Teeth Restored With Fiber Posts or Cast Metal Posts Recruiting NCT01461239 Phase 3
26 Evaluation of Postoperative Pain After Using 3MIX-TATIN Versus Calcium Hydroxide Iodoform Paste In Necrotic Primary Molars Treated by Lesion Sterilization and Tissue Repair Therapy Recruiting NCT03084601 Phase 2, Phase 3
27 Multicenter Trial Comparing One-step Partial Caries Removal to Complete Caries Removal for the Treatment of Deep Carious Lesions in Permanent Teeth. (DECAT : DEep CAries Treatment). Recruiting NCT02286388 Phase 3
28 Diclofenac Potassium on IANB Efficacy in Symptomatic Irreversible Pulpitis Active, not recruiting NCT03163420 Phase 2, Phase 3
29 Pre-operative Aceclofenac on the Anesthetic Efficacy of IANB in Symptomatic Irreversible Pulpitis Active, not recruiting NCT03146481 Phase 2, Phase 3
30 Regenerative Endodontic Procedure of Immature Permanent Teeth With L-PRF: a Pilot Controlled, Clinical Trial Active, not recruiting NCT02437708 Phase 3
31 Comparison Between Biodentine and Calcium Hydroxide in the Indirect Pulp Treatment on Primary Teeth Active, not recruiting NCT02799927 Phase 2, Phase 3
32 Evaluation of Post Operative Pain Following Indirect Pulp Capping Using Antibacterial Bonding System Active, not recruiting NCT02930135 Phase 2, Phase 3
33 Efficacy of Oral Prednisolone on Pain Reduction in Emergency Care of Acute Irreversible Pulpitis Not yet recruiting NCT02629042 Phase 3
34 A Clinical Study: the Antibacterial Effect of Insoluble Antibacterial Nanoparticles (IABN) Incorporated in Dental Materials for Root Canal Treatment Unknown status NCT01167985 Phase 2
35 Effect Of Different Lining Materials in Stepwise Excavation Unknown status NCT01730287 Phase 2
36 Efficacy of Chlorexidine as Intracanal Medicament in Primary Teeth Unknown status NCT00624572 Phase 2
37 Photodynamic Therapy in Endodontic Treatment Completed NCT02824601 Phase 2
38 Effect of Sufentanil on the Rate of Anesthesia Completed NCT01572116 Phase 2
39 Effect of Premedication on Success of Inferior Alveolar Nerve Block Injection Completed NCT02601911 Phase 2
40 Premedication Efficacy of Oral Ketorolac and Ketorolac/ Acetaminophen on Post Treatment Pain Completed NCT02614118 Phase 2
41 The Effects of Three Oral Medications on Post-operative Pain Following Endodontic Treatment Completed NCT01178203 Phase 1, Phase 2
42 Effect of Fentanyl on the Rate of Anesthesia Completed NCT01794533 Phase 2
43 MTA/FS Pulpotomy for Vital Primary Incisors: A Randomized Controlled Trial Completed NCT02019563 Phase 2
44 Chlorhexidine Intracanal Medicament in Periodontal Healing in Concomitant Endo Perio Lesion With Communication Completed NCT02627326 Phase 2
45 Efficacy of Different Drugs to Control Post Root Canal Treatment Pain Completed NCT02417337 Phase 2
46 Properties of Glass Ionomer Cements Associated With Chlorhexidine or Doxycycline Completed NCT02168374 Phase 2
47 Histological Change of The Dentinal-Pulp Complex and Root Resorption Completed NCT01642693 Phase 1, Phase 2
48 A Clinical Study to Compare Two Revascularization Protocols to Treat Non-vital Teeth With Incomplete Root Formation Recruiting NCT01827098 Phase 2
49 Periodontal Regeneration of Chronic Periodontal Disease Patients Receiving Stem Cells Injection Therapy Recruiting NCT02523651 Phase 1, Phase 2
50 Application of Photodynamic Therapy and Diode Laser for Endodontic Therapy of Young Permanent Teeth Recruiting NCT03074136 Phase 2

Search NIH Clinical Center for Dental Pulp Disease

Cochrane evidence based reviews: dental pulp diseases

Genetic Tests for Dental Pulp Disease

Anatomical Context for Dental Pulp Disease

Publications for Dental Pulp Disease

Articles related to Dental Pulp Disease:

id Title Authors Year
Diagnostic imaging in veterinary dental practice. Dental pulp disease in a river otter. ( 23971840 )

Variations for Dental Pulp Disease

Expression for Dental Pulp Disease

Search GEO for disease gene expression data for Dental Pulp Disease.

Pathways for Dental Pulp Disease

Pathways related to Dental Pulp Disease according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
Show member pathways
2 11.54 IL1B TAC1 TNF
3 10.8 IL1B TNF
4 10.3 IL1B TNF
5 9.83 IL1B TNF

GO Terms for Dental Pulp Disease

Biological processes related to Dental Pulp Disease according to GeneCards Suite gene sharing:

(show all 18)
id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.84 IL1B TAC1 TNF TRPV1
2 positive regulation of phagocytosis GO:0050766 9.58 IL1B TNF
3 positive regulation of interleukin-8 production GO:0032757 9.57 IL1B TNF
4 positive regulation of NF-kappaB import into nucleus GO:0042346 9.56 IL1B TNF
5 response to pain GO:0048265 9.55 TAC1 TRPV1
6 negative regulation of lipid catabolic process GO:0050995 9.52 IL1B TNF
7 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.51 IL1B TNF
8 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.49 IL1B TNF
9 positive regulation of synaptic transmission, GABAergic GO:0032230 9.48 NPS TAC1
10 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.46 IL1B TNF
11 positive regulation of chemokine biosynthetic process GO:0045080 9.43 IL1B TNF
12 regulation of establishment of endothelial barrier GO:1903140 9.4 IL1B TNF
13 positive regulation of action potential GO:0045760 9.37 NPS TAC1
14 positive regulation of nitric oxide biosynthetic process GO:0045429 9.33 IL1B TNF TRPV1
15 positive regulation of fever generation GO:0031622 9.32 IL1B TNF
16 sequestering of triglyceride GO:0030730 9.26 IL1B TNF
17 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 8.96 IL1B TNF
18 fever generation GO:0001660 8.62 IL1B TRPV1

Sources for Dental Pulp Disease

9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
32 HPO
33 ICD10
34 ICD10 via Orphanet
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
52 Novoseek
55 OMIM via Orphanet
59 PubMed
65 SNOMED-CT via Orphanet
68 Tocris
70 UMLS via Orphanet
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