Aliases & Classifications for Dentin Sensitivity

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Aliases & Descriptions for Dentin Sensitivity:

Name: Dentin Sensitivity 11 50 39 13 68
 
Sensitive Dentin 11

Classifications:



External Ids:

Disease Ontology11 DOID:698
MeSH39 D003807
SNOMED-CT62 13468005
NCIt45 C50778

Summaries for Dentin Sensitivity

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MalaCards based summary: Dentin Sensitivity, also known as sensitive dentin, is related to periodontitis and cervicitis, and has symptoms including toothache An important gene associated with Dentin Sensitivity is DSPP (Dentin Sialophosphoprotein), and among its related pathways are Hepatic ABC Transporters and Potassium Channels. Affiliated tissues include testes, and related mouse phenotypes are hearing/vestibular/ear and taste/olfaction.

Related Diseases for Dentin Sensitivity

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Diseases related to Dentin Sensitivity via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1periodontitis9.8
2cervicitis9.6
3gingivitis9.6
4childhood cerebral astrocytoma7.8ASIC3, CSN3, DSPP, ENTPD2, GJA1, KCNK10

Symptoms & Phenotypes for Dentin Sensitivity

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UMLS symptoms related to Dentin Sensitivity:


toothache

MGI Mouse Phenotypes related to Dentin Sensitivity according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.9ASIC3, GJA1, SIX1, TRPA1, TRPV4
2MP:00053949.1ENTPD2, SIX1, TRPA1, TRPV1
3MP:00107718.6ASIC3, CSN3, GJA1, TRPA1, TRPM3, TRPM8
4MP:00053868.5ASIC3, GJA1, KCNK2, SIX1, TRPA1, TRPM3
5MP:00036317.1ASIC3, ENTPD2, GJA1, KCNK10, KCNK2, KCNK4

Drugs & Therapeutics for Dentin Sensitivity

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Drugs for Dentin Sensitivity (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 95)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Calcium carbonateapprovedPhase 4215471-34-1
Synonyms:
CaCO3
Calcium carbonate
Calcium carbonate (1:1)
Calciumcarbonat
Carbonate de calcium
 
Carbonato de calcio
Carbonic acid calcium salt (1:1)
E 170
Kalziumkarbonat
Kohlensaurer kalk
Precipitated calcium carbonate
2
Etodolacapproved, investigational, vet_approvedPhase 42241340-25-43308
Synonyms:
(+-)-1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
(1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid
(1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid
1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid
1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid
1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid
110781-63-0 (mono-hydrochloride salt)
2-(1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid
41340-25-4
AB00052194
AC-4231
AC1L1FN2
AY 24,236
AY 24236
AY-24,236
AY-24236
AY24,236
AY24236
Acid, Etodolic
BPBio1_000333
BRD-A74667430-001-05-3
BSPBio_000301
BSPBio_003138
CCRIS 3923
CHEBI:126431
CHEBI:4909
CHEMBL622
CID3308
CPD000058443
D00315
D017308
DB00749
DivK1c_000147
E 0516
E0516_SIGMA
EU-0100479
Edolan
Etodolac
Etodolac (JP15/USP/INN)
Etodolac [USAN:BAN:INN]
Etodolac [USAN:INN:BAN]
Etodolac, (+-)-Isomer
Etodolac, Monosodium Salt
Etodolac, Monosodium Salt, (+-) Isomer
Etodolac, Monosodium Salt, (S)-Isomer
Etodolacetodolic acid
Etodolaco
Etodolaco [INN-Spanish]
Etodolacum
Etodolacum [INN-Latin]
Etodolic acid
Etodolsäure
HMS1568P03
 
HMS1921B09
HMS2092O20
HMS500H09
Hypen
IDI1_000147
KBio1_000147
KBio2_001724
KBio2_004292
KBio2_006860
KBio3_002358
KBioGR_000680
KBioSS_001724
LS-7393
Lodine
Lodine (TN)
Lodine SR
Lodine XL
Lopac0_000479
MLS000028474
MLS001077315
MolPort-001-759-084
NCGC00015399-04
NCGC00015399-11
NCGC00089769-02
NCGC00089769-03
NCGC00089769-04
NCGC00089769-05
NCGC00089769-06
NCGC00089769-07
NINDS_000147
NSC 282126
NSC282126
Osteluc
Prestwick0_000231
Prestwick1_000231
Prestwick2_000231
Prestwick3_000231
Prestwick_209
RAK-591
Ramodar
SAM002589968
SBB067257
SMR000058443
SPBio_001374
SPBio_002222
SPECTRUM1501005
Spectrum2_001387
Spectrum3_001429
Spectrum4_000410
Spectrum5_001347
Spectrum_001244
UNII-2M36281008
Ultradol
[1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetic acid
etodolac
Étodolac
3sodium fluorideapprovedPhase 4, Phase 2, Phase 3, Phase 12047681-49-4
4
Glycerolexperimental, approvedPhase 423856-81-5753
Synonyms:
1,2,3-Trihydroxypropane
1,2,3-propanetriol
1,2,3-trihydroxypropane
Bulbold
Cristal
E 422
Emery 916
Glyceol Opthalgan
Glycerin
Glycerin, anhydrous
Glycerin,anhydrous
Glycerine
Glycerinum
 
Glyceritol
Glycerol
Glycyl alcohol
Glyrol
Glysanin
IFP
Incorporation factor
Mackstat H 66
Monoctanoin component D
Osmoglyn
Pricerine 9091
Propanetriol
RG-S
Trihydroxypropane
Tryhydroxypropane
5FluoridesPhase 4, Phase 2, Phase 3, Phase 1462
6Bone Density Conservation AgentsPhase 4, Phase 2, Phase 33376
7Calcium, DietaryPhase 4, Phase 2, Phase 35713
8Anti-Infective AgentsPhase 4, Phase 2, Phase 3, Phase 122062
9Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 323689
10Anti-Infective Agents, LocalPhase 4, Phase 2, Phase 3, Phase 11880
11Protective AgentsPhase 4, Phase 2, Phase 3, Phase 17443
12Cariostatic AgentsPhase 4, Phase 2, Phase 3, Phase 1333
13
Hydrogen peroxidePhase 4, Phase 3, Phase 1637722-84-1784
Synonyms:
Adeka Super EL
Albone
Albone 35
Albone DS
Anti-Keim 50
Asepticper
Baquashock
CIX
Clarigel Gold
Crestal Whitestrips
Crystacide
Dentasept
Deslime LP
Hioxyl
Hipox
Hybrite
Hydrogen dioxide
Hydrogen peroxide
Inhibine
Lase Peroxide
Lensan A
 
Magic Bleaching
Metrokur
Mirasept
Nite White Excel 2
Odosat D
Opalescence Xtra
Oxigenal
Oxydol
Oxyfull
Oxysept
Oxysept I
Pegasyl
Perhydrol
Perone
Peroxaan
Peroxclean
Quasar Brite
Select Bleach
Superoxol
T-Stuff
Whiteness HP
Whitespeed
Xtra White
14Anti-Ulcer AgentsPhase 41842
15Gastrointestinal AgentsPhase 48402
16Cyclooxygenase InhibitorsPhase 4, Phase 32870
17AntacidsPhase 41842
18Pharmaceutical SolutionsPhase 4, Phase 2, Phase 18192
19Fluorides, TopicalPhase 454
20AnalgesicsPhase 4, Phase 311733
21Tin FluoridesPhase 4, Phase 3264
22
TinPhase 4, Phase 3737440-31-5
Synonyms:
CI Pigment metal 5
Haro Mix ZT-514
Innohep
Metallic tin
SN
 
Silver matt powder
Stanum
Tin flake
Tin powder
Tindamax
ZINN
23FluorophosphatePhase 4, Phase 3, Phase 260
24Cyclooxygenase 2 InhibitorsPhase 4624
25Analgesics, Non-NarcoticPhase 4, Phase 36501
26Antirheumatic AgentsPhase 4, Phase 310956
27Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 34443
28Anti-Inflammatory AgentsPhase 4, Phase 310729
29ListerinePhase 4, Phase 2, Phase 3, Phase 1204
30arginineNutraceuticalPhase 4, Phase 3425
31
Methamphetamineapproved, illicitPhase 2, Phase 3245537-46-210836
Synonyms:
(+ )-Methylamphetamine
(+ )-methylamphetamine
(+)-(S)-Deoxyephedrine
(+)-(S)-N-alpha-Dimethylphenethylamine
(+)-(S)-N-alpha-dimethylphenethylamine
(+)-(S)-N-α-dimethylphenethylamine
(+)-(S)-deoxyephedrine
(+)-(s)-deoxyephedrine
(+)-(s)-n-alpha-dimethylphenethylamine
(+)-2-(N-Methylamino)-1-phenylpropane
(+)-Methylamphetamine
(+)-N,alpha-Dimethyl-beta-phenylethylamine
(+)-N,alpha-Dimethylphenethylamine
(+)-N,alpha-dimethyl-beta-phenylethylamine
(+)-N,alpha-dimethylphenethylamine
(+)-N-Methylamphetamine
(+)-N-methylamphetamine
(+)-methamphetamine
(+)-methylamphetamine
(+)-n,alpha-dimethyl-beta-phenylethylamine
(+)-n,alpha-dimethylphenethylamine
(+)-n-methylamphetamine
(2S)-N-methyl-1-phenylpropan-2-amine
(AlphaS)-N,alpha-dimethylbenzeneethanamine
(S)-(+)-Deoxyephedrine
(S)-(+)-Methamphetamine
(S)-(+)-N,alpha,dimethylphenethylamine
(S)-(+)-deoxyephedrine
(S)-(+)-methamphetamine
(S)-Methamphetamine
(S)-Methylamphetamine
(S)-N,alpha-Dimethylbenzeneethanamine
(S)-N,alpha-Dimethylbenzeneethanoamine
(S)-N,alpha-dimethylbenzeneethanamine
(S)-N,alpha-dimethylbenzeneethanoamine
(S)-N,α-dimethylbenzeneethanamine
(S)-methamphetamine
(S)-methylamphetamine
(alphaS)-N,alpha-dimethylbenzeneethanamine
(s)-(+)-deoxyephedrine
(s)-(+)-methamphetamine
(s)-(+)-n,alpha,dimethylphenethylamine
(s)-methamphetamine
(s)-methylamphetamine
(s)-n,alpha-dimethylbenzeneethanamine
(s)-n,alpha-dimethylbenzeneethanoamine
(αS)-N,α-dimethylbenzeneethanamine
1-Phenyl-2-methylamino-propan
1-Phenyl-2-methylamino-propan [German]
1-Phenyl-2-methylaminopropane
139-47-9
14611-50-8
1690-86-4
2S-(+)-Methamphetamine
45952-89-4
537-46-2
AC1L1W1Z
AC1Q4SVR
B40
Benzeneethanamine, N,alpha-dimethyl-, (S)- (9CI)
Benzeneethanamine, N,alpha-dimethyl-, (alphaS)- (9CI)
C07164
C10H15N
CHEBI:6809
CHEMBL1201201
CID10836
Crank
Crank [Street Name]
Crystal Meth
Crystal Meth [Street Name]
D-(S)-Methamphetamine
D-(s)-methamphetamine
D-1-Phenyl-2-methylaminopropan
D-1-Phenyl-2-methylaminopropan [German]
D-1-Phenyl-2-methylaminopropane
D-Deoxyephedrine
D-Desoxyephedrine
D-Methamphetamine
D-Methylamphetamine
D-N,alpha-Dimethylphenethylamine
D-N,alpha-dimethylphenethylamine
D-N-Methylamphetamine
D-Phenylisopropylmethylamine
D-deoxyephedrine
D-desoxyephedrine
D-methamphetamine
D-methylamphetamine
 
D-n,alpha-dimethylphenethylamine
D-n-methylamphetamine
D-phenylisopropylmethylamine
D08187
DB01577
DEA No. 1105
Desoxyephedrine hydrochloride
Desoxyn
Desyphed
Desyphed hydrochloride
Dextromethamphetamine
EINECS 208-668-7
HSDB 3359
ICE [Street Name]
Ice
L-Methamphetamine
L-methamphetamine
LS-103331
METHAMPHETAMINE
Metamfetamina
Metamfetamina [INN-Spanish]
Metamfetamina [inn-spanish]
Metamfetamine
Metamfetamine (INN)
Metamfetamine [INN]
Metamfetamine-m
Metamfetaminum
Metamfetaminum [INN-Latin]
Metamfetaminum [Latin]
Metamfetaminum [inn-latin]
Metamphetamine
Metanfetamina
Metanfetamina [INN-Spanish]
Metanfetamina [Spanish]
Metanfetamina [inn-spanish]
Meth
Meth (Street Name)
Methamphetamine
Methamphetamine, its salts, isomers, and salts of its isomers
Methamphetaminum
Methamphetaminum [INN-Latin]
Methamphetaminum [JP]
Methamphetaminum [inn-latin]
Methyl-.beta.-phenylisopropylamine
Methyl-beta-phenylisopropylamine
Methylamphetamine
MolPort-001-794-405
Métamfétamine
N-Methyl-1-phenyl-2-propanamine
N-Methyl-beta-phenylisopropylamin
N-Methyl-beta-phenylisopropylamin [German]
N-Methyl-beta-phenylisopropylamin [german]
N-Methyl-beta-phenylisopropylamine
N-Methylamphetamine
N-methyl-beta-phenylisopropylamin [german]
N-methyl-beta-phenylisopropylamine
N-methylamphetamine
NSC 25115
NSC25115
Norodin
PDSP1_001404
PDSP1_001405
PDSP2_001388
PDSP2_001389
Phenethylamine, N,alpha-dimethyl-, (S)-(+)- (8CI)
S-(+)-Methamphetamine
S-(+)-methamphetamine
Speed
Speed [Street Name]
Stimulex
UNII-44RAL3456C
WLN: 1MY1&1R -D
d-(S)-Methamphetamine
d-1-Phenyl-2-methylaminopropan [German]
d-1-phenyl-2-methylaminopropane
d-Deoxyephedrine
d-Desoxyephedrine
d-Methamphetamine
d-Methylamphetamine
d-N,.alpha.-Dimethylphenethylamine
d-N-Methylamphetamine
d-N-methylamphetamine
d-Phenylisopropylmethylamine
d-deoxyephedrine
d-desoxyephedrine
d-phenylisopropylmethylamine
desohyephedrine
methyl-β-phenylisopropylamine
32
DopamineapprovedPhase 2, Phase 3383651-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
33
TriclosanapprovedPhase 3613380-34-55564
Synonyms:
112099-35-1
164325-69-3
2,4,4'-Trichloro-2'-hydroxy diphenyl ether
2,4,4'-Trichloro-2'-hydroxydiphenyl ether
2-Hydroxy-2',4,4'-trichlorodiphenyl Ether
261921-78-2
3380-34-5
5-CHLORO-2-(2,4-DICHLOROPHENOXY)PHENOL
5-Chloro-2-(2,4-dichloro-phenoxy)-phenol
524190_ALDRICH
72779_FLUKA
72779_SIGMA
88032-08-0
AC-10667
AC1L1KMN
Aquasept
BRN 2057142
C12059
C12H7Cl3O2
CCRIS 9253
CH 3565
CH-3565
CHEBI:164200
CHEMBL849
CID5564
CPD0-1227
CPD000471847
Caswell No. 186A
Clearasil Daily Face Wash
Cliniclean
Cloxifenol
Cloxifenolum
D014260
D06226
DB08604
DP-300
Dermtek Brand of Triclosan
EINECS 222-182-2
EPA Pesticide Chemical Code 054901
Ether, 2'-hydroxy-2,4,4'-trichlorodiphenyl
GlaxoSmithKline Brand of Triclosan
HMS2093L17
HSDB 7194
I01-2897
 
IN1424
Irgasan
Irgasan DP 300
Irgasan DP300
Johnson & Johnson Brand of Triclosan
LS-67854
Lexol 300
MLS001066347
MLS001074876
MLS001335937
MLS001335938
Manusept
Microshield T
MolPort-003-666-702
NCGC00159417-02
NCGC00159417-03
NCGC00159417-04
Oxy Skin Wash
Pharmachem Brand of Triclosan
Procter & Gamble Brand of Triclosan
Reckitt Brand of Triclosan
S00100
SAM002554907
SBB058565
SMR000471847
SSL Brand of Triclosan
Sapoderm
Ster Zac Bath Concentrate
Ster-Zac Bath Concentrate
SterZac Bath Concentrate
Stri-Dex Cleansing Bar
Stri-Dex Face Wash
Stri-Dex cleansing bar (TN)
TCL
TL8002539
Trans Canaderm Brand of Triclosan
Triclosan
Triclosan (USP/INN)
Triclosan Pharmachem Brand
Triclosan Reckitt Brand
Triclosan [USAN:BAN:INN]
Triclosanum
Triclosanum [INN-Latin]
Trisan
UNII-4NM5039Y5X
34
Salicylic acidapproved, vet_approvedPhase 318969-72-7338
Synonyms:
105910_ALDRICH
105910_SIAL
2 Hydroxybenzoic Acid
2-Carboxyphenol
2-Hydroxybenzenecarboxylate
2-Hydroxybenzenecarboxylic acid
2-Hydroxybenzoate
2-Hydroxybenzoic acid
2-hydroxy(1-14c)benzoic acid
247588_SIAL
27301_SIAL
69-72-7
7681-06-3
8052-31-1
84210_FLUKA
84210_SIAL
AB1002436
AC1L190M
AC1Q1HCK
AC1Q72IF
AI3-02407
AKOS000118979
ALPHA/BETA HYDROXY ACIDS (SALICYLIC ACID) (SEE ALPHA/BETA HYDROXY ACIDS)
AR-1E2203
ATA fraction 10, ammonium salt
Acid, 2-Hydroxybenzoic
Acid, Salicylic
Acid, o-Hydroxybenzoic
Acid, ortho-Hydroxybenzoic
Acido o-idrossibenzoico
Acido o-idrossibenzoico [Italian]
Acido salicilico
Acido salicilico [Italian]
Acidum salicylicum
Advanced Pain Relief Callus Removers
Advanced Pain Relief Corn Removers
Advanced pain relief callus removers
Advanced pain relief corn removers
Akurza Cream
Akurza Lotion
Alpha/Beta Hydroxy Acids (Glycolic Acid, Salicylic Acid)
BENZOIC ACID,2-HYDROXY SALICYLIC ACID
BIDD:ER0602
BRN 0774890
Benzoic acid, 2-hydroxy- (9CI)
C00805
CCRIS 6714
CHEBI:16914
CHEMBL424
CID338
CMC_13852
Caswell No. 731
Clear away Wart Remover
Clear away wart remover
Compound W
Compound w
D00097
D020156
DB00936
DHS Sal Shampoo
DivK1c_000301
Domerine
Dr. Scholl'S Callus Removers
Dr. Scholl'S Corn Removers
Dr. Scholl'S Wart Remover Kit
Dr. Scholl's callus removers
Dr. Scholl's corn removers
Dr. Scholl's wart remover kit
DuoPlant Gel
Duofil Wart Remover
Duofil wart remover
Duofilm
Duoplant
E9A559BE-383B-4F83-BC02-3031D03D558A
EINECS 200-712-3
EPA Pesticide Chemical Code 076602
Freezone
H0206
HSDB 672
Hydrisalic Gel
I04-0192
IDI1_000301
InChI=1/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10
Ionil
Ionil Plus
Ionil plus
Ionil-Plus
 
K 537
K 557
KBio1_000301
KBio2_001428
KBio2_003996
KBio2_006564
KBioSS_001428
Keralyt
Kyselina 2-hydroxybenzoova
Kyselina 2-hydroxybenzoova [Czech]
Kyselina salicylova
Kyselina salicylova [Czech]
LS-2169
MLS000069653
Mediplast pads
MolPort-001-769-476
NCGC00159447-02
NCGC00159447-04
NINDS_000301
NSC 180
NSC180
NSC629474
O-Carboxyphenol
O-Hydroxybenzoate
O-Hydroxybenzoic acid
O-carboxyphenol
O-hydroxybenzoic acid
Occlusal
Oprea1_040343
Orthohydroxybenzoic acid
P&S Shampoo
Phenol-2-carboxylate
Phenol-2-carboxylic acid
Propa pH Peel-Off Acne Mask
Psoriacid-S-Stift
Psoriacid-S-stift
Retarder SAX
Retarder W
Rutranex
S5922_SIGMA
S7401_SIGMA
S8519_SIGMA
SALICYLIC ACID (SEE ALSO ALPHA HYDROXY ACIDS)
SALICYLIC ACID, ACS
SAX
SBB052826
SGCUT00012
SMP2_000145
SMR000059163
STK258681
Salex Cream
Salex Lotion
Salicyclic acid
Salicylate
Salicylic acid
Salicylic acid & Sulfur Soap
Salicylic acid (6CI,8CI)
Salicylic acid (JP15/USP)
Salicylic acid (TN)
Salicylic acid Soap
Salicylic acid [USAN:JAN]
Salicylic acid collodion
Salicylic acid soap
Salicylic acid, tech
Salicylic acid, tech.
Salicylic acid-ring-UL-14C
Saligel
Salonil
Sebucare
Sebulex
Spectrum_000948
Stri-Dex
Trans-Ver-Sal
UNII-O414PZ4LPZ
UPCMLD-DP126
UPCMLD-DP126:001
Verrugon
W398500_ALDRICH
WLN: QVR BQ
bmse000252
o Hydroxybenzoic Acid
o-Carboxyphenol
o-hydroxybenzoic acid
ortho Hydroxybenzoic Acid
ortho-Hydroxybenzoic Acid
phenol derivative, 7
salicylate
salicylic acid
to_000004
35
Piroxicamapproved, investigationalPhase 32736322-90-45280452, 54676228
Synonyms:
(3E)-3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxo-1
(4-Hydroxy-2-methyl-1,1-dioxobenzo[e]1,2-thiazin-3-yl)-N-(2-pyridyl)carboxamide
2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide
3-[hydroxy(pyridin-2-ylamino)methylidene]-2-methyl-3,4-dihydro-2H-1
36322-90-4
4-Hydroxy-2-methyl-3-(pyrid-2-yl-carbamoyl)-2H-1,2-benzothiazine 1,1-dioxide
4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid
4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid [German]
4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
4-Hydroxy-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
4-hydroxy-2-methyl-N-pyridin-2-yl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
AC-12216
AC1NQX1P
AC1Q3XLJ
AK1015
AKOS000714958
Akten
Apo-Piroxicam
Artroxicam
BAS 04381594
BAXO
BRN 0627692
Baxo
Bio-0759
Bruxicam
C01608
C15H13N3O4S
CCRIS 3719
CHEBI:8249
CHEMBL527
CHF 1251
CID5280452
CP 16171
CP-16171
CP16171
Caliment
D00127
D010894
DB00554
EINECS 252-974-3
EU-0100900
Erazon
Felden
 
Feldene
Feldene (TN)
Feldene Fast
Feldene Gel
Feldene, Roxam, Piroxicam
Flogobene
Geldene
HMS1362D11
HMS1568L03
HMS1792D11
HMS1920H22
HMS1990D11
HMS2092A05
HMS501C11
Improntal
LS-7663
Larapam
MolPort-001-888-120
NSC 666076
NSC666076
P 5654
P0847_SIAL
Pipoxicam
Pirkam
Piroflex
Piroftal
Piroxicam
Piroxicam (JP15/USP/INN)
Piroxicam [USAN:BAN:INN:JAN]
Piroxicamum
Piroxicamum [INN-Latin]
Prestwick_573
Pyroxycam
Reudene
Riacen
Roxicam
Roxiden
S1713_Selleck
SPECTRUM1500491
STK177288
Sasulen
Solocalm
UNII-13T4O6VMAM
Zunden
piroxicam
piroxicam usp
36Central Nervous System StimulantsPhase 2, Phase 32211
37AnestheticsPhase 2, Phase 39596
38Neurotransmitter Uptake InhibitorsPhase 2, Phase 33521
39Neurotransmitter AgentsPhase 2, Phase 318340
40Autonomic AgentsPhase 2, Phase 310150
41Dopamine AgentsPhase 2, Phase 33836
42Dopamine Uptake InhibitorsPhase 2, Phase 31331
43Adrenergic AgentsPhase 2, Phase 35352
44Trace ElementsPhase 36001
45Hypolipidemic AgentsPhase 32785
46AntimetabolitesPhase 312054
47Lipid Regulating AgentsPhase 32766
48MicronutrientsPhase 36001
49
SiliconPhase 31037440-21-34082203
Synonyms:
Si
 
Silica
Silicate
Silicic acid
50
BetadexPhase 3207585-39-9320761
Synonyms:
Betadex, INN, USAN
Cyclo-hepta-amylose
Cycloheptaamylose
Cycloheptaglucan
Cycloheptaglucosan
Cycloheptakis-(1->4)-(a-D-glucopyranose)
Cycloheptamaltose
 
Cycloheptapentylose
Cyclomaltoheptaose
E459
b-Schardinger dextran
beta -cycloamylose
beta -cyclodextrin
beta -cycloheptaamylose
beta Cyclodextrin, USAN
beta-Cyclodextrin

Interventional clinical trials:

(show top 50)    (show all 129)
idNameStatusNCT IDPhase
1Efficacy of Two Oral Hygiene Regimens in the Reduction of Dentin Hypersensitivity After Periodontal TreatmentCompletedNCT02461030Phase 4
2Clinical Study of the Whitening Dentifrices on Tooth Color and SensitivityCompletedNCT02483013Phase 4
3Nano-hydroxyapatite With Potassium Nitrate in the Therapy of the Dental SensitivityCompletedNCT02895321Phase 4
4The Effect of Desensitizing Agents in In-home or In-office Dental BleachingCompletedNCT02316080Phase 4
5Study to Investigate the Efficacy of an Occluding Dentifrice in Providing Relief From Dentine HypersensitivityCompletedNCT02773758Phase 4
6Longevity and Effectiveness of Bleaching in Healthy and Smokers PatientsCompletedNCT02017873Phase 4
7Etodolac and Post-bleaching SensitivityCompletedNCT02881619Phase 4
8Short Term Clinical Study Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal HypersensitivityCompletedNCT02731833Phase 4
9To Investigate the Efficacy of an Occluding Dentifrice in Dentinal Hypersensitivity (DH)CompletedNCT02923895Phase 4
10Dose Response of a Tubule Occlusion AgentCompletedNCT01075256Phase 4
11An Evaluation of the Efficacy of Oral-B New Product Sensi-Stop on Dentinal HypersensitivityCompletedNCT02476032Phase 4
12Clinical Effectiveness of In-office Bleaching Activated With a LED/Laser DeviceCompletedNCT01231243Phase 4
13Efficacy of a Whitening Dentifrice on Tooth DiscolorationCompletedNCT02741427Phase 4
14Effectiveness of Nanohydroxyapetite Paste on Reducing Dentin HypersensitivityRecruitingNCT02936830Phase 4
15Combined Bleaching Technique: Efficacy and Tooth SensitivityActive, not recruitingNCT03089216Phase 4
16The Efficacy of Cyanoacrylate Adhesive (PeriAcryl®90 HV) in Periodontal Wound HealingNot yet recruitingNCT02826109Phase 4
17Evaluation of Dentin Hypersensitivity Using Glass Ionomer CementsUnknown statusNCT02378129Phase 2, Phase 3
18Dentin Treatments for Restorations of Cervical Lesions Non-CariousUnknown statusNCT02434601Phase 2, Phase 3
19Effectiveness of a Homecare Dentin Hypersensitivity GelCompletedNCT02128633Phase 2, Phase 3
20Cyanoacrylate and Laser and Dentin SensitivityCompletedNCT01111474Phase 3
21IN-OFFICE TOOTH BLEACHING WITH 37% CARBAMIDE PEROXIDECompletedNCT02935114Phase 3
22Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal HypersensitivityCompletedNCT01827670Phase 3
23Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal HypersensitivityCompletedNCT02832375Phase 3
24The Efficacy of a Toothpaste to Reduce SensitivityCompletedNCT00763269Phase 3
25The Efficacy of a Dentifrice in Providing Relief From Dentinal HypersensitivityCompletedNCT01724008Phase 3
26The Efficacy of a Dentifrice in Providing Relief From Immediate and Short Term Relief From Dentinal HypersensitivityCompletedNCT03072719Phase 3
27The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal HypersensitivityCompletedNCT01592864Phase 3
28Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal HypersensitivityCompletedNCT01592851Phase 3
29Postoperative Hypersensitivity Randomized Comparative Effectiveness Research TrialCompletedNCT01268605Phase 3
30Noncarious Cervical Lesion Treatment OutcomesCompletedNCT00867997Phase 3
31Outcome Evaluation of Ceramic Crowns Using Two Different Dental CementsCompletedNCT00591942Phase 3
32Effectiveness of Arginin and Potassium Nitrate Dentifrices in Dentin Hypersensitivity TherapyRecruitingNCT02829879Phase 3
33Potassium Oxalate and Potassium Nitrate and Post-bleaching SensitivityRecruitingNCT02941653Phase 3
34Comparison of Different Desensitizers in Reducing Dentinal HypersensitivityRecruitingNCT03177109Phase 3
35Piroxicam-beta-Cyclodextrin on Tooth Sensitivity Caused by In-office BleachingActive, not recruitingNCT03153657Phase 3
36Comparison Between Biodentine and Calcium Hydroxide in the Indirect Pulp Treatment on Primary TeethActive, not recruitingNCT02799927Phase 2, Phase 3
37Clinical Evaluation of Esthetic Restorations Placed in Primary Molars With Composite Resin Enriched With Insoluble Anti Bacterial Nano ParticlesUnknown statusNCT00389714Phase 2
38Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and CreamCompletedNCT02918617Phase 2
39Efficacy of Potassium Nitrate Solution in Reducing Dentinal HypersensitivityCompletedNCT01115452Phase 2
40Clinical Study Investigating the Efficacy of a Mouthwash in Providing Long Term Relief From Dentinal HypersensitivityCompletedNCT02226562Phase 2
41Exploratory Study to Evaluate an Occlusion Based Dentifrice in Relief of Dentinal HypersensitivityCompletedNCT01691560Phase 2
42Exploratory Study to Evaluate the Efficacy of an Occlusion Based Dentifrice in Relief of Dentinal HypersensitivityCompletedNCT01831817Phase 2
43Clinical Performance of 3-Unit FPDsCompletedNCT00223431Phase 2
44Clinical Trial of the Effect of Different Categories of Adhesive SystemActive, not recruitingNCT02751970Phase 2
45Evaluation of Biodentine Versus Glass Ionomer Cement in Treatment of Very Deep Carious LesionsNot yet recruitingNCT02868918Phase 2
46Evaluation of the Effect of Fluoride and Laser Application on the Prevention of Sensitivity in Bleached TeethCompletedNCT03044171Phase 1
47Pharmacokinetics of Diammine Silver FluorideCompletedNCT01664871Phase 1
48The Effects of Potassium Nitrate in Reducing Dentinal HypersensitivityCompletedNCT01587950Phase 1
49Effects of DIammine SIlver Fluoride on Tooth SensitivityUnknown statusNCT01063530
50Tooth Bleaching for Young Patients Using a Hydrogen Peroxide-based GelUnknown statusNCT02414464

Search NIH Clinical Center for Dentin Sensitivity


Cochrane evidence based reviews: dentin sensitivity

Genetic Tests for Dentin Sensitivity

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Anatomical Context for Dentin Sensitivity

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MalaCards organs/tissues related to Dentin Sensitivity:

36
Testes

Publications for Dentin Sensitivity

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Articles related to Dentin Sensitivity:

(show all 26)
idTitleAuthorsYear
1
Randomized trial of the clinical efficacy of a potassium oxalate-containing mouthrinse in rapid relief of dentin sensitivity. (24282871)
2013
2
Biomimetic mineralization: long-term observations in patients with dentin sensitivity. (22305715)
2012
3
Oxalic acid under adhesive restorations as a means to reduce dentin sensitivity: a four-month clinical trial. (21777095)
2011
4
Human odontoblasts express functional thermo-sensitive TRP channels: implications for dentin sensitivity. (21168271)
2011
5
Dentin sensitivity: an oral symptom that should not be neglected]. (19575978)
2009
6
Considerations for the development of over-the-counter dentifrices for the treatment and relief of dentin sensitivity. (19902641)
2009
7
Clinical evaluation of cervical dentin sensitivity (CDS) in patients attending general dental clinics (GDC) and periodontal specialty clinics (PSC). (11908469)
2002
8
Root-dentin sensitivity following non-surgical periodontal treatment. (10983603)
2000
9
Treatment of dentin sensitivity with stannous fluoride gel. Electron microscopic study and evaluation of dentin permeability]. (9567615)
1997
10
The Dentin Disc surface: a plausible model for dentin physiology and dentin sensitivity evaluation. (9470509)
1997
11
Theory of dentin sensitivity. (8534375)
1994
12
Dental pain evoked by hydrostatic pressures applied to exposed dentin in man: a test of the hydrodynamic theory of dentin sensitivity. (7996085)
1994
13
Relation of dentin sensitivity to histological changes in dog teeth with exposed and stimulated dentin. (1508867)
1992
14
Dentin permeability and dentin sensitivity. (1508886)
1992
15
Evaluation of tartar control dentifrices in in vitro models of dentin sensitivity. (1650304)
1991
16
An in vivo study of dentin sensitivity: the relation of dentin sensitivity and the patency of dentin tubules. (1753319)
1991
17
Mechanisms of dentin sensitivity. (2197121)
1990
18
The influence of frequent ingestion of acids in the diet on treatment for dentin sensitivity. (2285881)
1990
19
Double-blind evaluation of duration of dentin sensitivity reduction by fluoride iontophoresis. (2638286)
1989
20
The efficacy of a new dentifrice in treating dentin sensitivity: effects of sodium citrate and sodium fluoride as active ingredients. (2953887)
1987
21
Dentin permeability, dentin sensitivity, and treatment through tubule occlusion. (3465852)
1986
22
Dentin sensitivity: a review. (3860500)
1985
23
Clinical evaluation of the effectiveness of three dentifrices in relieving dentin sensitivity. (6596425)
1984
24
Dentin sensitivity, odontoblasts and nerves under desiccated or infected experimental cavities. A clinical, light microscopic and ultrastructural investigation. (6955990)
1982
25
Dentin sensitivity and aspiration of odontoblasts. (14014982)
1963
26
Sodium fluoride therapy for combating dentin sensitivity and gingival decay. (21008391)
1945

Variations for Dentin Sensitivity

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Expression for genes affiliated with Dentin Sensitivity

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Search GEO for disease gene expression data for Dentin Sensitivity.

Pathways for genes affiliated with Dentin Sensitivity

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Pathways related to Dentin Sensitivity according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.2KCNK10, KCNK2, KCNK4
2
Show member pathways
9.2KCNK10, KCNK2, KCNK4
3
Show member pathways
8.4TRPM3, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4
48.1TRPA1, TRPM3, TRPM8, TRPV1, TRPV2, TRPV3
5
Show member pathways
8.1ASIC3, TRPA1, TRPM8, TRPV1, TRPV2, TRPV3
6
Show member pathways
7.9ASIC3, TRPA1, TRPM3, TRPM8, TRPV1, TRPV2
7
Show member pathways
7.9ASIC3, TRPA1, TRPM3, TRPM8, TRPV1, TRPV2

GO Terms for genes affiliated with Dentin Sensitivity

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Cellular components related to Dentin Sensitivity according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1integral component of plasma membraneGO:00058878.1ASIC3, GJA1, KCNK2, KCNK4, TRPA1, TRPV1
2integral component of membraneGO:00160216.5ASIC3, ENTPD2, GJA1, KCNK10, KCNK2, KCNK4
3plasma membraneGO:00058865.7ASIC3, ENTPD2, GJA1, KCNK10, KCNK2, KCNK4

Biological processes related to Dentin Sensitivity according to GeneCards Suite gene sharing:

(show all 30)
idNameGO IDScoreTop Affiliating Genes
1diet induced thermogenesisGO:000202410.8TRPV1, TRPV4
2response to painGO:004826510.8TRPA1, TRPV1
3detection of temperature stimulus involved in sensory perception of painGO:005096510.8ASIC3, TRPV1
4detection of mechanical stimulus involved in sensory perception of painGO:005096610.8ASIC3, TRPA1
5response to pHGO:000926810.7GJA1, TRPV1
6detection of temperature stimulusGO:001604810.7TRPM3, TRPM8
7cellular response to temperature stimulusGO:007150210.6KCNK4, TRPV1
8detection of chemical stimulus involved in sensory perception of painGO:005096810.6ASIC3, TRPA1, TRPV1
9negative regulation of cardiac muscle cell proliferationGO:006004410.5GJA1, KCNK2
10negative regulation of DNA biosynthetic processGO:200027910.5GJA1, KCNK2
11positive regulation of cytosolic calcium ion concentrationGO:000720410.5GJA1, TRPV1, TRPV4
12protein homotetramerizationGO:005128910.5TRPA1, TRPM8, TRPV1
13thermoceptionGO:005095510.5TRPA1, TRPM8, TRPV1
14cation transportGO:000681210.4ASIC3, TRPM3, TRPM8
15sensory perception of painGO:001923310.4KCNK4, TRPA1, TRPV1
16response to mechanical stimulusGO:000961210.4ASIC3, KCNK2, TRPV4
17sensory perception of temperature stimulusGO:005095110.2KCNK4, TRPM3, TRPM8
18sensory perceptionGO:000760010.2ASIC3, TRPV2
19positive regulation of calcium ion importGO:009028010.2TRPV2, TRPV3
20memoryGO:000761310.0KCNK10, KCNK2, KCNK4
21potassium ion transmembrane transportGO:007180510.0KCNK10, KCNK2, KCNK4
22potassium ion transportGO:000681310.0KCNK10, KCNK2, KCNK4
23response to temperature stimulusGO:00092669.8TRPM8, TRPV2, TRPV3
24response to heatGO:00094089.7ASIC3, TRPV1, TRPV2, TRPV3
25ion transmembrane transportGO:00342209.2ASIC3, GJA1, TRPA1, TRPM3, TRPM8, TRPV1
26calcium ion transmembrane transportGO:00705888.9TRPA1, TRPM3, TRPM8, TRPV1, TRPV2, TRPV3
27calcium ion transportGO:00068168.9TRPA1, TRPM3, TRPM8, TRPV1, TRPV2, TRPV3
28transmembrane transportGO:00550858.0CSN3, GJA1, TRPA1, TRPM3, TRPM8, TRPV1
29ion transportGO:00068117.4ASIC3, KCNK10, KCNK2, KCNK4, TRPA1, TRPM3
30transportGO:00068106.3ASIC3, GJA1, KCNK10, KCNK2, KCNK4, TRPA1

Molecular functions related to Dentin Sensitivity according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1calcium-release channel activityGO:001527810.6TRPA1, TRPV1
2temperature-gated cation channel activityGO:00976049.8KCNK4, TRPA1
3ion transmembrane transporter activityGO:00150759.8GJA1, TRPV2
4ion channel activityGO:00052169.7TRPV1, TRPV2, TRPV4
5potassium channel activityGO:00052679.1KCNK10, KCNK2, KCNK4
6cation channel activityGO:00052619.0ASIC3, TRPM3, TRPV1, TRPV2, TRPV3, TRPV4
7calcium channel activityGO:00052628.7TRPA1, TRPM3, TRPM8, TRPV1, TRPV2, TRPV3

Sources for Dentin Sensitivity

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet