MCID: DNT008
MIFTS: 39

Denture Stomatitis malady

Categories: Oral diseases

Aliases & Classifications for Denture Stomatitis

Aliases & Descriptions for Denture Stomatitis:

Name: Denture Stomatitis 12 14
Stomatitis, Denture 42 69
Denture Sore Mouth 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11875
ICD10 33 K12.1
MeSH 42 D013282
SNOMED-CT 64 196576008 69254008
UMLS 69 C0038364

Summaries for Denture Stomatitis

MalaCards based summary : Denture Stomatitis, also known as stomatitis, denture, is related to stomatitis and oculomotor nerve paralysis. An important gene associated with Denture Stomatitis is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions. The drugs Miconazole and Nystatin have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, colon and testes.

Related Diseases for Denture Stomatitis

Diseases related to Denture Stomatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
id Related Disease Score Top Affiliating Genes
1 stomatitis 31.8 CXCL8 IL6
2 oculomotor nerve paralysis 10.3 CXCL8 IL6
3 common peroneal nerve lesion 10.3 CXCL8 IL6
4 neonatal hypoxic and ischemic brain injury 10.3 CXCL8 IL6
5 thymic neuroendocrine carcinoma 10.3 CXCL8 IL6
6 psychotic disorder 10.3 CXCL8 IL6
7 retinal vascular disease 10.3 CXCL8 IL6
8 childhood electroclinical syndrome 10.3 CXCL8 IL6
9 acute panmyelosis with myelofibrosis 10.2 CXCL8 IL6
10 cutaneous candidiasis 10.2 CCL2 CXCL8
11 labyrinthine bilateral reactive loss 10.2 CXCL8 IL6
12 esophagus lymphoma 10.2 CXCL8 IL6
13 larynx carcinoma in situ 10.2 CXCL8 IL6
14 bullous retinoschisis 10.2 CXCL8 IL6
15 japanese spotted fever 10.2 CCL2 CXCL8
16 carbuncle 10.2 CXCL8 IL6
17 vitreoretinopathy, neovascular inflammatory 10.2 CXCL8 IL6
18 larynx leiomyoma 10.2 CXCL8 IL6
19 ulcerative proctitis 10.2 CCL2 CXCL8
20 trichomalacia 10.2 CXCL8 IL6
21 cicatricial lagophthalmos 10.2 CXCL8 IL6
22 neuroaxonal dystrophy 10.2 CCL2 IL6
23 gastric dilatation 10.2 CXCL8 IL6
24 cryptosporidiosis 10.2 CCL2 IL6
25 acquired thrombocytopenia 10.2 CXCL8 IL6
26 supratentorial primitive neuroectodermal tumor 10.2 CCL2 IL6
27 glucose intolerance 10.2 CCL2 CXCL8
28 steroid dehydrogenase deficiency dental anomalies 10.2 CCL2 IL6
29 smooth muscle tumor 10.2 CCL2 IL6
30 autosomal recessive type iv ehlers-danlos syndrome 10.2 CXCL8 IL6
31 orthostatic proteinuria 10.2 CXCL8 IL6
32 pyriform sinus cancer 10.2 CCL2 IL6
33 erb-duchenne and dejerine-klumpke palsies 10.2 CXCL8 IL6
34 immune-complex glomerulonephritis 10.2 CCL2 IL6
35 lepromatous leprosy 10.2 CA6 IL6
36 neuropathy 10.2 CXCL8 IL6
37 bladder signet ring cell adenocarcinoma 10.2 CCL2 IL6
38 choanal atresia, bilateral 10.1 CCL2 IL6
39 inappropriate adh syndrome 10.1 CXCL8 IL6
40 strawberry gallbladder 10.1 CCL2 CXCL8
41 motility-related diarrhea 10.1 CCL2 IL6
42 mixed mineral dust pneumoconiosis 10.1 CCL2 CXCL8 IL6
43 atrophy of prostate 10.1 CCL2 CXCL8 IL6
44 breast apocrine carcinoma in situ 10.1 CCL2 CXCL8 IL6
45 infancy electroclinical syndrome 10.1 CCL2 CXCL8 IL6
46 baritosis 10.1 CCL2 CXCL8 IL6
47 amelogenesis imperfecta 10.1 CCL2 CXCL8 IL6
48 neovascular glaucoma 10.1 CCL2 CXCL8 IL6
49 optic nerve hypoplasia 10.1 CCL2 CXCL8 IL6
50 sclerosing adenosis of breast 10.1 CCL2 CXCL8 IL6

Graphical network of the top 20 diseases related to Denture Stomatitis:



Diseases related to Denture Stomatitis

Symptoms & Phenotypes for Denture Stomatitis

Drugs & Therapeutics for Denture Stomatitis

Drugs for Denture Stomatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 43)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
2
Nystatin Approved, Vet_approved Phase 4,Phase 2 1400-61-9 11953884
3
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
4
Methylene blue Investigational Phase 4 61-73-4
5 Anti-Bacterial Agents Phase 4,Phase 2
6 Antifungal Agents Phase 4,Phase 3,Phase 2
7 Anti-Infective Agents Phase 4,Phase 3,Phase 2
8 Ionophores Phase 4,Phase 2
9 Pharmaceutical Solutions Phase 4
10 Castor Oil Phase 4
11 Disinfectants Phase 4
12 Epinephryl borate Phase 4
13 Eusol Phase 4
14 Racepinephrine Phase 4
15
s 1 (combination) Phase 4
16 Sodium hypochlorite Phase 4
17 Castor Nutraceutical Phase 4
18 Anti-Infective Agents, Local Phase 3
19 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
20 Cytochrome P-450 CYP3A Inhibitors Phase 3
21 Cytochrome P-450 Enzyme Inhibitors Phase 3
22 Hormone Antagonists Phase 3
23 Hormones Phase 3
24 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
25 Propolis Phase 3
26 Steroid Synthesis Inhibitors Phase 3
27 Bee Products Nutraceutical Phase 3
28
Clotrimazole Approved, Vet_approved Phase 2 23593-75-1 2812
29 Garlic Nutraceutical Phase 2
30 Titanium dioxide Approved Phase 1 13463-67-7
31 Dermatologic Agents Phase 1
32 Photosensitizing Agents Phase 1
33 Protective Agents Phase 1
34 Radiation-Protective Agents Phase 1
35 Sunscreening Agents Phase 1
36
Mechlorethamine Approved 51-75-2 4033
37
Chlorhexidine Approved, Vet_approved 55-56-1 9552079 2713
38 Alkylating Agents
39 Antineoplastic Agents, Alkylating
40 chloramine-T
41 Chlorhexidine gluconate
42 Anti-Inflammatory Agents
43 Sage Nutraceutical

Interventional clinical trials:

(show all 15)
id Name Status NCT ID Phase
1 Photodynamic Therapy Against Candida Spp. in Complete Denture Wearers Completed NCT02642900 Phase 4
2 Effectiveness of Hygiene Solutions on Denture Biofilm Completed NCT02407834 Phase 4
3 Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic Completed NCT02818803 Phase 3
4 Effect of Aqueous Extract of Garlic and Nystatin Mouthwash in Denture Stomatitis Completed NCT01198223 Phase 2
5 Efficacy of Slow Release Clotrimazole Varnish Treating Denture Stomatitis Comparing to Traditional Treatment of Troches Completed NCT00835029 Phase 2
6 The Effect of Palatal Brushing on Denture Stomatitis Completed NCT01643876 Phase 1
7 Surface Roughness of Heat Cured Acrylic Resin Versus Acrylic Resin With Titanium Dioxide Not yet recruiting NCT02950584 Phase 1
8 Effects of Denture-Related Stomatitis on Blood Pressure in Denture Wearers Unknown status NCT02166450
9 Efficacy of a Propolis-based Denture Cleanser Completed NCT01237782
10 Experimental Denture Pastes Completed NCT01237795
11 Hygiene Protocol of Complete Dentures Completed NCT01906242
12 The Effectiveness of Palatal Brushing on Denture Stomatitis Recruiting NCT02686632
13 Novel Coating to Minimize Bacterial Adhesions and Tooth Wear in Denture Acrylic Recruiting NCT02834832
14 Clinical Trial for Evaluating Sage-Based Mouthrinse Recruiting NCT02830802
15 Microbiological Study on Maxillary Complete Dentures of Two Different Materials Not yet recruiting NCT02950623

Search NIH Clinical Center for Denture Stomatitis

Cochrane evidence based reviews: stomatitis, denture

Genetic Tests for Denture Stomatitis

Anatomical Context for Denture Stomatitis

MalaCards organs/tissues related to Denture Stomatitis:

39
Neutrophil, Colon, Testes, Monocytes, T Cells, Endothelial, Tongue

Publications for Denture Stomatitis

Articles related to Denture Stomatitis:

(show top 50) (show all 237)
id Title Authors Year
1
Fabrication and Evaluation of Nanostructured Herbal Oil/Hydroxypropyl-I^-Cyclodextrin/Polyvinylpyrrolidone Mats for Denture Stomatitis Prevention and Treatment. ( 26821915 )
2016
2
Candida albicans biofilm heterogeneity does not influence denture stomatitis, but strongly influences denture cleansing capacity. ( 28032543 )
2016
3
EVALUATION OF DENTURE-RELATED FACTORS PREDISPOSING TO DENTURE STOMATITIS IN A LEBANESE POPULATION. ( 27999492 )
2016
4
Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals. ( 26971635 )
2016
5
Systemic T Cells and Monocyte Characteristics in Patients with Denture Stomatitis. ( 26883670 )
2016
6
Evidence Regarding the Treatment of Denture Stomatitis. ( 27062660 )
2016
7
Transcription Factors Efg1 and Bcr1 Regulate Biofilm Formation and Virulence during Candida albicans-Associated Denture Stomatitis. ( 27453977 )
2016
8
Clinical study on thermography, as modern investigation method for Candida-associated denture stomatitis. ( 27151707 )
2016
9
Sustained drug-delivery system: a promising therapy for denture stomatitis? ( 27812610 )
2016
10
Antifungal Effect of Henna against Candida albicans Adhered to Acrylic Resin as a Possible Method for Prevention of Denture Stomatitis. ( 27223294 )
2016
11
Decreased production of proinflammatory cytokines by monocytes from individuals presenting Candida-associated denture stomatitis. ( 26587801 )
2016
12
Interventions for the Management of Denture Stomatitis: A Systematic Review and Meta-Analysis. ( 27889906 )
2016
13
Denture Stomatitis and Candida Albicans in Iranian Population: A Systematic Review and Meta-Analysis. ( 27840842 )
2016
14
Invitro Antifungal Evaluation of Denture Soft Liner Incorporated with Tea Tree Oil: A New Therapeutic Approach Towards Denture Stomatitis. ( 26266221 )
2015
15
The Beneficial Effect of Equisetum giganteum L. against Candida Biofilm Formation: New Approaches to Denture Stomatitis. ( 26290676 )
2015
16
Uncaria tomentosa Gel against Denture Stomatitis: Clinical Report. ( 25675972 )
2015
17
Expression of Secreted Aspartyl Proteinases in an Experimental Model of Candida albicans-Associated Denture Stomatitis. ( 25857681 )
2015
18
Photodynamic inactivation of virulence factors of Candida strains isolated from patients with denture stomatitis. ( 26398815 )
2015
19
Methylene Blue-Mediated Photodynamic Inactivation Followed by Low-Laser Therapy versus Miconazole Gel in the Treatment of Denture Stomatitis. ( 26375599 )
2015
20
A case with tumor of left parotid gland and denture stomatitis. ( 25826511 )
2015
21
Is denture stomatitis always related with candida infection? A case control study. ( 25082257 )
2014
22
Evaluation of different treatment methods against denture stomatitis: a randomized clinical study. ( 24908596 )
2014
23
Phase 1 clinical trial on the effect of palatal brushing on denture stomatitis. ( 25010873 )
2014
24
Antifungal medications or disinfectants for denture stomatitis. ( 24971864 )
2014
25
Linking evidence to treatment for denture stomatitis: A meta-analysis of randomized controlled trials. ( 24316341 )
2014
26
Role of salivary and candidal proteins in denture stomatitis: an exploratory proteomic analysis. ( 24947908 )
2014
27
Antifungal Activity of Apple Cider Vinegar on Candida Species Involved in Denture Stomatitis. ( 25219289 )
2014
28
Use of Candida-specific chicken egg yolk antibodies to inhibit the adhering of Candida to denture base materials: prevention of denture stomatitis. ( 25393605 )
2014
29
Risk factors associated with denture stomatitis in healthy subjects attending a dental school in southeast iran. ( 24273669 )
2013
30
Salivary cytokine profile in elders with Candida-related denture stomatitis. ( 23829887 )
2013
31
Denture stomatitis and salivary vascular endothelial growth factor in immediate complete denture wearers with type 2 diabetes. ( 24355506 )
2013
32
Opportunistic microorganisms in individuals with lesions of denture stomatitis. ( 23747028 )
2013
33
Treatment protocol for denture stomatitis, prior to anatomical molding. ( 22506854 )
2013
34
Does the presence of anterior mandibular teeth increase the incidence of denture stomatitis? ( 22984815 )
2013
35
Clinical and histological findings of denture stomatitis as related to intraoral colonization patterns of Candida albicans, salivary flow, and dry mouth. ( 23107189 )
2013
36
Susceptibility profile of a Brazilian yeast stock collection of Candida species isolated from subjects with Candida-associated denture stomatitis with or without diabetes. ( 24055150 )
2013
37
Ricinus communis treatment of denture stomatitis in institutionalised elderly. ( 23438045 )
2013
38
Brazilian green propolis compared to miconazole gel in the treatment of Candida-associated denture stomatitis. ( 23737855 )
2013
39
Effects of lawsone methyl ether mouthwash on oral Candida in HIV-infected subjects and subjects with denture stomatitis. ( 23586936 )
2013
40
The association of denture stomatitis and partial removable dental prostheses: a systematic review. ( 22371829 )
2012
41
Development of a contemporary animal model of Candida albicans-associated denture stomatitis using a novel intraoral denture system. ( 22392931 )
2012
42
Comparison of therapeutic effect of aqueous extract of garlic and nystatin mouthwash in denture stomatitis. ( 22126338 )
2012
43
In vitro activities of new triazole antifungal agents, posaconazole and voriconazole, against oral Candida isolates from patients suffering from denture stomatitis. ( 21842426 )
2012
44
Activation pattern of neutrophils from blood of elderly individuals with Candida-related denture stomatitis. ( 22120419 )
2012
45
In vitro Candida albicans biofilm induced proteinase activity and SAP8 expression correlates with in vivo denture stomatitis severity. ( 22302440 )
2012
46
Comparison of denture microwave disinfection and conventional antifungal therapy in the treatment of denture stomatitis: a randomized clinical study. ( 22986242 )
2012
47
Salivary immunity in elderly individuals presented with Candida-related denture stomatitis. ( 21453417 )
2012
48
Elucidating role of salivary proteins in denture stomatitis using a proteomic approach. ( 23041753 )
2012
49
Microwave denture disinfection versus nystatin in treating patients with well-controlled type 2 diabetes and denture stomatitis: a randomized clinical trial. ( 22545252 )
2012
50
The pattern recognition receptors expressed on neutrophils and the associated cytokine profile from different aged patients with Candida-related denture stomatitis. ( 22796226 )
2012

Variations for Denture Stomatitis

Expression for Denture Stomatitis

Search GEO for disease gene expression data for Denture Stomatitis.

Pathways for Denture Stomatitis

GO Terms for Denture Stomatitis

Biological processes related to Denture Stomatitis according to GeneCards Suite gene sharing:

(show all 19)
id Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.63 BCR CCL2 IL6
2 inflammatory response GO:0006954 9.62 CCL2 CXCL8 CXCR1 IL6
3 chemotaxis GO:0006935 9.61 CCL2 CXCL8 CXCR1
4 humoral immune response GO:0006959 9.58 CCL2 IL6
5 response to heat GO:0009408 9.58 CCL2 IL6
6 monocyte chemotaxis GO:0002548 9.57 CCL2 IL6
7 receptor internalization GO:0031623 9.56 CXCL8 CXCR1
8 cellular response to estradiol stimulus GO:0071392 9.55 CCL2 IL6
9 response to amino acid GO:0043200 9.54 CCL2 IL6
10 cellular response to tumor necrosis factor GO:0071356 9.54 CCL2 CXCL8 IL6
11 cellular response to dexamethasone stimulus GO:0071549 9.52 CCL2 IL6
12 response to bacterium GO:0009617 9.51 CCL2 IL6
13 response to antibiotic GO:0046677 9.49 CCL2 IL6
14 cellular response to fibroblast growth factor stimulus GO:0044344 9.48 CCL2 CXCL8
15 cellular response to interleukin-1 GO:0071347 9.43 CCL2 CXCL8 IL6
16 PERK-mediated unfolded protein response GO:0036499 9.4 CCL2 CXCL8
17 chemokine-mediated signaling pathway GO:0070098 9.33 CCL2 CXCL8 CXCR1
18 regulation of vascular endothelial growth factor production GO:0010574 8.96 CCL2 IL6
19 cellular response to lipopolysaccharide GO:0071222 8.92 BCR CCL2 CXCL8 IL6

Molecular functions related to Denture Stomatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 8.96 CCL2 CXCL8
2 cytokine activity GO:0005125 8.8 CCL2 CXCL8 IL6

Sources for Denture Stomatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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