MCID: DNT008
MIFTS: 38

Denture Stomatitis

Categories: Oral diseases

Aliases & Classifications for Denture Stomatitis

MalaCards integrated aliases for Denture Stomatitis:

Name: Denture Stomatitis 12 14
Stomatitis, Denture 42 69
Denture Sore Mouth 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11875
ICD10 33 K12.1
MeSH 42 D013282
SNOMED-CT 64 196576008 69254008
UMLS 69 C0038364

Summaries for Denture Stomatitis

MalaCards based summary : Denture Stomatitis, also known as stomatitis, denture, is related to stomatitis and oculomotor nerve paralysis. An important gene associated with Denture Stomatitis is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and Spinal Cord Injury. The drugs Miconazole and Nystatin have been mentioned in the context of this disorder. Affiliated tissues include colon, neutrophil and testes.

Related Diseases for Denture Stomatitis

Diseases related to Denture Stomatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 108)
id Related Disease Score Top Affiliating Genes
1 stomatitis 11.0
2 oculomotor nerve paralysis 10.6 CXCL8 IL6
3 common peroneal nerve lesion 10.6 CXCL8 IL6
4 drug rash with eosinophilia and systemic symptoms 10.6 CXCL8 IL6
5 spirillary rat-bite fever 10.6 CXCL8 IL6
6 psychotic disorder 10.6 CXCL8 IL6
7 infancy electroclinical syndrome 10.6 CXCL8 IL6
8 acute myeloblastic leukemia without maturation 10.6 CXCL8 IL6
9 labyrinthine bilateral reactive loss 10.6 CXCL8 IL6
10 pasteurellosis 10.6 CXCL8 IL6
11 osteogenesis imperfecta, type x 10.6 CXCL8 IL6
12 subglottis neoplasm 10.6 CXCL8 IL6
13 bullous retinoschisis 10.6 CXCL8 IL6
14 cicatricial lagophthalmos 10.6 CXCL8 IL6
15 carbuncle 10.6 CXCL8 IL6
16 cytomegalovirus retinitis 10.6 CCL2 CXCL8
17 autosomal dominant polycystic kidney disease 10.6 CXCL8 IL6
18 orthostatic proteinuria 10.6 CXCL8 IL6
19 tricho onychic dysplasia 10.6 CXCL8 IL6
20 flinders island spotted fever 10.6 CCL2 CXCL8
21 acquired thrombocytopenia 10.6 CXCL8 IL6
22 dysphagia 10.6 CXCL8 IL6
23 antigen-peptide-transporter 2 deficiency 10.6 CCL2 IL6
24 myeloid sarcoma 10.6 CXCL8 IL6
25 stargardt macular degeneration absent or hypoplastic corpus callosum mental retardation and dysmorphic features 10.6 CCL2 IL6
26 tumefactive multiple sclerosis 10.6 CCL2 CXCL8
27 steatorrhea 10.5 CCL2 CXCL8
28 esophagus leiomyoma 10.5 CXCL8 IL6
29 intracranial primitive neuroectodermal tumor 10.5 CCL2 IL6
30 palmoplantar keratosis 10.5 CXCL8 IL6
31 islet cell tumor 10.5 CCL2 IL6
32 neuroaxonal dystrophy 10.5 CCL2 IL6
33 breast disease 10.5 CXCL8 IL6
34 hyperaldosteronism 10.5 CCL2 IL6
35 bardet-biedl syndrome 8 10.5 CXCL8 IL6
36 cytomegalovirus disease in patients with impaired cell mediated immunity deemed at risk 10.5 CCL2 IL6
37 vacterl association 10.5 CXCL8 IL6
38 uterine corpus dissecting leiomyoma 10.5 CXCL8 IL6
39 diffuse glomerulonephritis 10.5 CCL2 IL6
40 louping ill 10.5 CCL2 CXCL8
41 lichen planus 10.5 CCL2 IL6
42 alcohol abuse 10.5 CXCL8 IL6
43 esophagus melanoma 10.5 CXCL8 IL6
44 high pressure neurological syndrome 10.5 CCL2 IL6
45 ostertagiasis 10.5 CCL2 IL6
46 necrotic uveal melanoma 10.5 CXCL8 IL6
47 osmotic diarrhea 10.5 CCL2 IL6
48 endocervical type cervical mucinous adenocarcinoma 10.5 CXCL8 IL6
49 adenocarcinoid tumor 10.5 CXCL8 IL6
50 focal dystonia 10.5 CCL2 IL6

Graphical network of the top 20 diseases related to Denture Stomatitis:



Diseases related to Denture Stomatitis

Symptoms & Phenotypes for Denture Stomatitis

Drugs & Therapeutics for Denture Stomatitis

Drugs for Denture Stomatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 40)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
2
Nystatin Approved, Vet_approved Phase 4,Phase 2 1400-61-9 11953884
3 Castor oil Approved, Vet_approved Phase 4
4
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
5 Racepinephrine Approved Phase 4
6
Methylene blue Investigational Phase 4 61-73-4
7 Anti-Bacterial Agents Phase 4,Phase 2
8 Antifungal Agents Phase 4,Phase 3,Phase 2
9 Anti-Infective Agents Phase 4,Phase 3,Phase 2
10 Ionophores Phase 4,Phase 2
11 Pharmaceutical Solutions Phase 4
12 Disinfectants Phase 4
13 Epinephryl borate Phase 4
14 Eusol Phase 4
15
s 1 (combination) Phase 4
16 Sodium hypochlorite Phase 4
17 Castor Nutraceutical Phase 4
18 Anti-Infective Agents, Local Phase 3
19 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
20 Cytochrome P-450 CYP3A Inhibitors Phase 3
21 Cytochrome P-450 Enzyme Inhibitors Phase 3
22 Hormone Antagonists Phase 3
23 Hormones Phase 3
24 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
25 Propolis Phase 3
26 Steroid Synthesis Inhibitors Phase 3
27 Bee Products Nutraceutical Phase 3
28
Clotrimazole Approved, Vet_approved Phase 2 23593-75-1 2812
29 Garlic Approved, Nutraceutical Phase 2
30 Titanium dioxide Approved Phase 1 13463-67-7
31 Dermatologic Agents Phase 1
32 Photosensitizing Agents Phase 1
33 Protective Agents Phase 1
34 Radiation-Protective Agents Phase 1
35 Sunscreening Agents Phase 1
36
Chlorhexidine Approved, Vet_approved 55-56-1 9552079 2713
37
Mechlorethamine Approved 51-75-2 4033
38 Chlorhexidine gluconate
39 Alkylating Agents
40 chloramine-T

Interventional clinical trials:

(show all 15)

id Name Status NCT ID Phase Drugs
1 Photodynamic Therapy Against Candida Spp. in Complete Denture Wearers Completed NCT02642900 Phase 4 Nystatin 100.000 units
2 Effectiveness of Hygiene Solutions on Denture Biofilm Completed NCT02407834 Phase 4
3 Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic Completed NCT02818803 Phase 3 Miconazole
4 Effect of Aqueous Extract of Garlic and Nystatin Mouthwash in Denture Stomatitis Completed NCT01198223 Phase 2 garlic , nystatin
5 Efficacy of Slow Release Clotrimazole Varnish Treating Denture Stomatitis Comparing to Traditional Treatment of Troches Completed NCT00835029 Phase 2 Clotrimazole varnish;Clotrimazole troches
6 The Effect of Palatal Brushing on Denture Stomatitis Completed NCT01643876 Phase 1
7 Surface Roughness of Heat Cured Acrylic Resin Versus Acrylic Resin With Titanium Dioxide Not yet recruiting NCT02950584 Phase 1
8 Effects of Denture-Related Stomatitis on Blood Pressure in Denture Wearers Unknown status NCT02166450 Nystatin
9 Hygiene Protocol of Complete Dentures Completed NCT01906242
10 Efficacy of a Propolis-based Denture Cleanser Completed NCT01237782 Denture soaking solution;Saline solution
11 Experimental Denture Pastes Completed NCT01237795
12 Clinical and Laboratorial Evaluation of the Desinfection Solutions in Candida Species From Total Prostheses and Palate of Total Edentulous. Completed NCT03203551
13 The Effectiveness of Palatal Brushing on Denture Stomatitis Recruiting NCT02686632
14 Novel Coating to Minimize Bacterial Adhesions and Tooth Wear in Denture Acrylic Recruiting NCT02834832
15 Microbiological Study on Maxillary Complete Dentures of Two Different Materials Not yet recruiting NCT02950623

Search NIH Clinical Center for Denture Stomatitis

Cochrane evidence based reviews: stomatitis, denture

Genetic Tests for Denture Stomatitis

Anatomical Context for Denture Stomatitis

MalaCards organs/tissues related to Denture Stomatitis:

39
Colon, Neutrophil, Testes, Monocytes, Endothelial, T Cells, Tongue

Publications for Denture Stomatitis

Articles related to Denture Stomatitis:

(show top 50) (show all 246)
id Title Authors Year
1
Laboratory-Based Investigation of Denture Sonication Method in Patients with Candida-Associated Denture Stomatitis. ( 28872720 )
2017
2
Efficacy of Propolis on the Denture Stomatitis Treatment in Older Adults: A Multicentric Randomized Trial. ( 28396692 )
2017
3
Oral Candida carriage and species prevalence in denture stomatitis patients with and without diabetes. ( 28685534 )
2017
4
Efficacy of photodynamic therapy in the inactivation of oral fungal colonization among cigarette smokers and non-smokers with denture stomatitis. ( 28130176 )
2017
5
In Vitro Evaluation of the Inhibitory Activity of Thymoquinone in Combatting Candida albicans in Denture Stomatitis Prevention. ( 28698449 )
2017
6
Inhibitory effect of zirconium oxide nanoparticles on Candida albicans adhesion to repaired polymethyl methacrylate denture bases and interim removable prostheses: a new approach for denture stomatitis prevention. ( 28814859 )
2017
7
Nystatin and disinfectant solutions seem to be effective in treating denture stomatitis. ( 28242007 )
2017
8
Phagocytosis and nitric oxide production by peritoneal adherent cells in response to Candida albicans in aging: a collaboration to elucidate the pathogenesis of denture stomatitis. ( 28678945 )
2017
9
Characterization of a novel antibiofilm effect of nitric oxide-releasing aspirin (NCX-4040) on Candida albicans isolates from denture stomatitis patients. ( 28493889 )
2017
10
Sustained drug-delivery system: a promising therapy for denture stomatitis? ( 27812610 )
2016
11
Decreased production of proinflammatory cytokines by monocytes from individuals presenting Candida-associated denture stomatitis. ( 26587801 )
2016
12
Clinical study on thermography, as modern investigation method for Candida-associated denture stomatitis. ( 27151707 )
2016
13
Denture Stomatitis and Candida Albicans in Iranian Population: A Systematic Review and Meta-Analysis. ( 27840842 )
2016
14
Candida albicans biofilm heterogeneity does not influence denture stomatitis, but strongly influences denture cleansing capacity. ( 28032543 )
2016
15
Antifungal Effect of Henna against Candida albicans Adhered to Acrylic Resin as a Possible Method for Prevention of Denture Stomatitis. ( 27223294 )
2016
16
Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals. ( 26971635 )
2016
17
Interventions for the Management of Denture Stomatitis: A Systematic Review and Meta-Analysis. ( 27889906 )
2016
18
Evidence Regarding the Treatment of Denture Stomatitis. ( 27062660 )
2016
19
Systemic T Cells and Monocyte Characteristics in Patients with Denture Stomatitis. ( 26883670 )
2016
20
EVALUATION OF DENTURE-RELATED FACTORS PREDISPOSING TO DENTURE STOMATITIS IN A LEBANESE POPULATION. ( 27999492 )
2016
21
Transcription Factors Efg1 and Bcr1 Regulate Biofilm Formation and Virulence during Candida albicans-Associated Denture Stomatitis. ( 27453977 )
2016
22
Fabrication and Evaluation of Nanostructured Herbal Oil/Hydroxypropyl-I^-Cyclodextrin/Polyvinylpyrrolidone Mats for Denture Stomatitis Prevention and Treatment. ( 26821915 )
2016
23
Uncaria tomentosa Gel against Denture Stomatitis: Clinical Report. ( 25675972 )
2015
24
Photodynamic inactivation of virulence factors of Candida strains isolated from patients with denture stomatitis. ( 26398815 )
2015
25
Methylene Blue-Mediated Photodynamic Inactivation Followed by Low-Laser Therapy versus Miconazole Gel in the Treatment of Denture Stomatitis. ( 26375599 )
2015
26
A case with tumor of left parotid gland and denture stomatitis. ( 25826511 )
2015
27
The Beneficial Effect of Equisetum giganteum L. against Candida Biofilm Formation: New Approaches to Denture Stomatitis. ( 26290676 )
2015
28
Invitro Antifungal Evaluation of Denture Soft Liner Incorporated with Tea Tree Oil: A New Therapeutic Approach Towards Denture Stomatitis. ( 26266221 )
2015
29
Expression of Secreted Aspartyl Proteinases in an Experimental Model of Candida albicans-Associated Denture Stomatitis. ( 25857681 )
2015
30
Evaluation of different treatment methods against denture stomatitis: a randomized clinical study. ( 24908596 )
2014
31
Use of Candida-specific chicken egg yolk antibodies to inhibit the adhering of Candida to denture base materials: prevention of denture stomatitis. ( 25393605 )
2014
32
Linking evidence to treatment for denture stomatitis: A meta-analysis of randomized controlled trials. ( 24316341 )
2014
33
Phase 1 clinical trial on the effect of palatal brushing on denture stomatitis. ( 25010873 )
2014
34
Is denture stomatitis always related with candida infection? A case control study. ( 25082257 )
2014
35
Role of salivary and candidal proteins in denture stomatitis: an exploratory proteomic analysis. ( 24947908 )
2014
36
Antifungal medications or disinfectants for denture stomatitis. ( 24971864 )
2014
37
Antifungal Activity of Apple Cider Vinegar on Candida Species Involved in Denture Stomatitis. ( 25219289 )
2014
38
Salivary cytokine profile in elders with Candida-related denture stomatitis. ( 23829887 )
2013
39
Opportunistic microorganisms in individuals with lesions of denture stomatitis. ( 23747028 )
2013
40
Susceptibility profile of a Brazilian yeast stock collection of Candida species isolated from subjects with Candida-associated denture stomatitis with or without diabetes. ( 24055150 )
2013
41
Clinical and histological findings of denture stomatitis as related to intraoral colonization patterns of Candida albicans, salivary flow, and dry mouth. ( 23107189 )
2013
42
Effects of lawsone methyl ether mouthwash on oral Candida in HIV-infected subjects and subjects with denture stomatitis. ( 23586936 )
2013
43
Denture stomatitis and salivary vascular endothelial growth factor in immediate complete denture wearers with type 2 diabetes. ( 24355506 )
2013
44
Brazilian green propolis compared to miconazole gel in the treatment of Candida-associated denture stomatitis. ( 23737855 )
2013
45
Ricinus communis treatment of denture stomatitis in institutionalised elderly. ( 23438045 )
2013
46
Treatment protocol for denture stomatitis, prior to anatomical molding. ( 22506854 )
2013
47
Risk factors associated with denture stomatitis in healthy subjects attending a dental school in southeast iran. ( 24273669 )
2013
48
Does the presence of anterior mandibular teeth increase the incidence of denture stomatitis? ( 22984815 )
2013
49
Microbial colonization and their relation with potential cofactors in patients with denture stomatitis. ( 23151692 )
2012
50
Comparison of denture microwave disinfection and conventional antifungal therapy in the treatment of denture stomatitis: a randomized clinical study. ( 22986242 )
2012

Variations for Denture Stomatitis

Expression for Denture Stomatitis

Search GEO for disease gene expression data for Denture Stomatitis.

Pathways for Denture Stomatitis

GO Terms for Denture Stomatitis

Biological processes related to Denture Stomatitis according to GeneCards Suite gene sharing:

(show all 19)
id Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.63 BCR CCL2 IL6
2 inflammatory response GO:0006954 9.62 CCL2 CXCL8 CXCR1 IL6
3 chemotaxis GO:0006935 9.61 CCL2 CXCL8 CXCR1
4 humoral immune response GO:0006959 9.58 CCL2 IL6
5 response to heat GO:0009408 9.58 CCL2 IL6
6 cellular response to tumor necrosis factor GO:0071356 9.58 CCL2 CXCL8 IL6
7 monocyte chemotaxis GO:0002548 9.57 CCL2 IL6
8 receptor internalization GO:0031623 9.56 CXCL8 CXCR1
9 cellular response to estradiol stimulus GO:0071392 9.55 CCL2 IL6
10 response to antibiotic GO:0046677 9.54 CCL2 IL6
11 cellular response to dexamethasone stimulus GO:0071549 9.52 CCL2 IL6
12 response to amino acid GO:0043200 9.51 CCL2 IL6
13 response to bacterium GO:0009617 9.49 CCL2 IL6
14 cellular response to fibroblast growth factor stimulus GO:0044344 9.48 CCL2 CXCL8
15 cellular response to interleukin-1 GO:0071347 9.43 CCL2 CXCL8 IL6
16 PERK-mediated unfolded protein response GO:0036499 9.37 CCL2 CXCL8
17 chemokine-mediated signaling pathway GO:0070098 9.33 CCL2 CXCL8 CXCR1
18 regulation of vascular endothelial growth factor production GO:0010574 8.96 CCL2 IL6
19 cellular response to lipopolysaccharide GO:0071222 8.92 BCR CCL2 CXCL8 IL6

Molecular functions related to Denture Stomatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 8.96 CCL2 CXCL8
2 cytokine activity GO:0005125 8.8 CCL2 CXCL8 IL6

Sources for Denture Stomatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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