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MCID: DRM006
MIFTS: 66

Dermatitis malady

Categories: Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Dermatitis

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Aliases & Descriptions for Dermatitis:

Name: Dermatitis 12 52 42 14 69
Eczema 12 29 52 41 14 69
Inflammatory Dermatosis 69
Skin Inflammation 12

Classifications:

MalaCards categories:
Anatomical: Skin diseases
See all MalaCards categories (disease lists)
ICD10: 33


Sources

Summaries for Dermatitis

About this section
MedlinePlus : 41 eczema is a term for several different types of skin swelling. eczema is also called dermatitis. most types cause dry, itchy skin and rashes on the face, inside the elbows and behind the knees, and on the hands and feet. scratching the skin can cause it to turn red, and to swell and itch even more. eczema is not contagious. the cause is not known. it is likely caused by both genetic and environmental factors. eczema may get better or worse over time, but it is often a long-lasting disease. people who have it may also develop hay fever and asthma. the most common type of eczema is atopic dermatitis. it is most common in babies and children but adults can have it too. as children who have atopic dermatitis grow older, this problem may get better or go away. but sometimes the skin may stay dry and get irritated easily. treatments may include medicines, skin creams, light therapy, and good skin care. you can prevent some types of eczema by avoiding things that irritate your skin, such as certain soaps, fabrics, and lotions stress things you are allergic to, such as food, pollen, and animals nih: national institute of arthritis and musculoskeletal and skin diseases

MalaCards based summary : Dermatitis, also known as eczema, is related to subcorneal pustular dermatosis and lactose intolerance, and has symptoms including exanthema and pruritus. An important gene associated with Dermatitis is IL31 (Interleukin 31), and among its related pathways/superpathways are PEDF Induced Signaling and TGF-Beta Pathway. The drugs Fluocinonide and Petrolatum have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and testes, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 A skin disease characterized by itchy, erythematous, vesicular, weeping and crusting patches of skin.

Wikipedia : 71 Dermatitis, also known as eczema, is a group of diseases that results in inflammation of the skin. These... more...

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Related Diseases for Dermatitis

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Diseases related to Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 638)
id Related Disease Score Top Affiliating Genes
1 subcorneal pustular dermatosis 32.2 IFNG IL13 IL4 IL5
2 lactose intolerance 29.4 IL13 IL4 IL5
3 colon adenocarcinoma 29.4 CCL11 IL4 IL5
4 actinic keratosis 29.4 IL13 IL4 IL5
5 multiple carboxylase deficiency 29.3 IFNG IL4 IL5
6 glucocorticoid resistance 29.3 CCL11 IFNG IGHE IL13 IL4 IL5
7 epidermolysis bullosa 27.9 BCL7B CCL11 CCL17 CCL22 CCL27 CMA1
8 atopic dermatitis 12.4
9 contact dermatitis 12.3
10 seborrheic dermatitis 12.3
11 allergic contact dermatitis 12.3
12 dermatitis herpetiformis 12.3
13 irritant dermatitis 12.3
14 cercarial dermatitis 12.2
15 seborrheic infantile dermatitis 12.1
16 chronic actinic dermatitis 12.1
17 autoimmune progesterone dermatitis 12.1
18 seborrhea-like dermatitis with psoriasiform elements 12.1
19 dermatitis, atopic 2 12.0
20 contagious pustular dermatitis 12.0
21 exfoliative dermatitis 12.0
22 atopic dermatitis 3 12.0
23 infective dermatitis associated with htlv-1 11.9
24 microcephaly, congenital cataract and psoriasiform dermatitis 11.9
25 occupational dermatitis 11.9
26 toxicodendron dermatitis 11.9
27 atopic dermatitis 5 11.9
28 atopic dermatitis 6 11.9
29 atopic dermatitis 7 11.9
30 atopic dermatitis 4 11.9
31 phototoxic dermatitis 11.9
32 photoallergic dermatitis 11.9
33 atopic dermatitis 8 11.9
34 atopic dermatitis 9 11.9
35 granulomatous dermatitis 11.9
36 juvenile dermatitis herpetiformis 11.8
37 spongiotic dermatitis 11.8
38 dermatitis herpetiformis, familial 11.8
39 interstitial granulomatous dermatitis with arthritis 11.8
40 eczema herpeticum 11.7
41 agammaglobulinemia, microcephaly, and severe dermatitis 11.7
42 acneiform dermatitis 11.7
43 allergic contact dermatitis of eyelid 11.7
44 eczematous dermatitis of eyelid 11.6
45 neurotic excoriation 11.5
46 erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis, and hyper ige 11.4
47 blau syndrome 11.2
48 pompholyx 11.2
49 acrodermatitis enteropathica 11.2
50 bullous pemphigoid 11.1

Graphical network of the top 20 diseases related to Dermatitis:



Diseases related to Dermatitis
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Symptoms & Phenotypes for Dermatitis

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UMLS symptoms related to Dermatitis:


exanthema, pruritus

MGI Mouse Phenotypes related to Dermatitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.85 CCL11 CCL17 CMA1 IFNG IL13 IL31RA
2 immune system MP:0005387 9.65 IL5 PHF11 TSLP CCL11 CCL17 CMA1
3 respiratory system MP:0005388 9.17 CCL11 IFNG IL13 IL4 IL5 PHF11
Sources

Drugs & Therapeutics for Dermatitis

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Drugs for Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 538)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluocinonide Approved, Investigational Phase 4 356-12-7 9642
2
Petrolatum Approved Phase 4,Phase 3,Phase 1,Phase 2 8009-03-8
3
Bacitracin Approved, Vet_approved Phase 4,Phase 3,Phase 2 1405-87-4 439542 10909430
4
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-23-7 5754 657311
5 Sodium thiosulfate Approved Phase 4,Phase 3
6
Ciclopirox Approved, Investigational Phase 4,Phase 3 29342-05-0 2749
7
Isotretinoin Approved Phase 4,Phase 3 4759-48-2 5538 5282379
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
9
Salicylic acid Approved, Vet_approved Phase 4 69-72-7 338
10
Glycerol Approved, Experimental Phase 4,Phase 3,Phase 1,Phase 2 56-81-5 753
11
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
12
Triamcinolone Approved, Vet_approved Phase 4,Phase 2 124-94-7 31307
13
Cetuximab Approved Phase 4,Phase 3,Phase 2 205923-56-4 56842117 2333
14
Desonide Approved, Investigational Phase 4,Phase 3 638-94-8 5311066
15
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 75614-87-8, 51-45-6 774
16
Montelukast Approved Phase 4 158966-92-8 5281040
17
Ethanol Approved Phase 4,Phase 3,Phase 1 64-17-5 702
18
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
19
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
20
Zinc Approved Phase 4,Phase 3,Phase 2 7440-66-6 32051 23994
21
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 378-44-9 9782
22
Ephedrine Approved Phase 4,Phase 2 299-42-3 9294
23
Pseudoephedrine Approved Phase 4,Phase 2 90-82-4 7028
24
Menthol Approved Phase 4,Phase 3,Phase 2 2216-51-5 16666
25
Dapsone Approved, Investigational Phase 4 80-08-0 2955
26
Pimecrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137071-32-0 6447131 17753757
27
Cortisone acetate Approved Phase 4,Phase 2 1950-04-4, 50-04-4 5745
28
Cetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1 83881-51-0 2678
29
Levocetirizine Approved Phase 4,Phase 3,Phase 1 130018-77-8
30
Omalizumab Approved, Investigational Phase 4,Phase 2,Phase 1 242138-07-4
31
Mupirocin Approved, Investigational, Vet_approved Phase 4 12650-69-0 446596
32
Ketoconazole Approved, Investigational Phase 4,Phase 3 65277-42-1 47576 3823
33
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
34
Benzocaine Approved Phase 4,Phase 3,Phase 1,Phase 2 1994-09-7, 94-09-7 2337
35
Adapalene Approved Phase 4,Phase 1 106685-40-9 60164
36
Benzoyl peroxide Approved Phase 4 94-36-0 7187
37
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
38
Zinc oxide Approved Phase 4,Phase 3,Phase 2 1314-13-2
39
Adalimumab Approved Phase 4,Phase 2 331731-18-1 16219006
40
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
41
Sorafenib Approved, Investigational Phase 4,Phase 1 284461-73-0 216239 406563
42
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 79217-60-0, 59865-13-3 5284373 6435893
43 Titanium dioxide Approved Phase 4 13463-67-7
44
Alitretinoin Approved, Investigational Phase 4,Phase 3 5300-03-8 444795
45
Desoximetasone Approved Phase 4 382-67-2 5311067
46
Clotrimazole Approved, Vet_approved Phase 4 23593-75-1 2812
47
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 59-02-9 14985
48
Calcitriol Approved, Nutraceutical Phase 4,Phase 2 32222-06-3 134070 5280453
49
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 59-30-3 6037
50
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2 58-05-9 54575, 6560146 143

Interventional clinical trials:

(show top 50) (show all 1085)
id Name Status NCT ID Phase
1 VANOS Cream and Skin Barrier Function Unknown status NCT00819507 Phase 4
2 Efficacy of KAM2904 Face Cream and KAM3008 Body Lotion Treatment in Children With Atopic Dermatitis (AD) Unknown status NCT01781663 Phase 4
3 Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents Unknown status NCT01797562 Phase 4
4 Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea Unknown status NCT01139749 Phase 4
5 Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation Unknown status NCT00779792 Phase 4
6 Skin Changes in Head and Neck Cancer During Immuno-(Chemo-) And Radiotherapy With Erbitux® (HICARE) Unknown status NCT01553032 Phase 4
7 Quaternium-15, Use Test Unknown status NCT00311454 Phase 4
8 The Randomized Controlled Clinical Trial of Kushen Injection Unknown status NCT02346318 Phase 4
9 Effect of Moisturizing Creams on Skin Barrier Function Unknown status NCT00771121 Phase 4
10 Effects of Pimecrolimus Cream 1% on the Molecular and Cellular Profile of Adult Male Patients With Atopic Dermatitis Completed NCT00117377 Phase 4
11 A Study Evaluating the Efficacy of Fluocinonide Cream 0.1% (Vanos) in Subjects With Atopic Dermatitis Completed NCT01049243 Phase 4
12 Open Label Study of Long Term Treatment of Pediatric Treatment of Atopic Dermatitis With Pimecrolimus Cream 1% Within a Usual Clinical Setting Completed NCT00509990 Phase 4
13 Comparison of Pimecrolimus Cream 1% Twice-Daily to Once-Daily Dosing in the Management of Atopic Dermatitis in Pediatric Subjects Completed NCT00139581 Phase 4
14 Efficacy and Tolerability of New Topical Formulations in Subjects With Atopic Dermatitis Completed NCT02732314 Phase 4
15 Adherence to Topical Hydrocortisone 17-butyrate 0.1% (Locoid®) Using Different Vehicles in Adults With Atopic Dermatitis Completed NCT00693693 Phase 4
16 Elidel-Study: Elidel in Patients With Atopic Dermatitis Completed NCT00180141 Phase 4
17 Study to Evaluate the Safety and Efficacy of Alefacept (Amevive) in Subjects With Moderate to Severe Atopic Dermatitis Completed NCT00832585 Phase 4
18 Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food Allergens Completed NCT00557284 Phase 4
19 Epiceramâ„¢ Device Versus Mid-Strength Topical Steroid (Fluticasone Propionate 0.05%) for Treatment of Atopic Dermatitis Completed NCT00616538 Phase 4
20 A Comparison Study Between Protopic (Tacrolimus) Ointment and Elidel (Pimecrolimus) Cream in Treating Subjects With Atopic Dermatitis Completed NCT00666302 Phase 4
21 A Clinical Study in Children and Adolescents With Mild to Moderate Atopic Dermatitis Completed NCT00568412 Phase 4
22 Comparison Study Between Protopic (Tacrolimus Ointment) and Elidel (Pimecrolimus Cream) in Treating Pediatric Patients With Atopic Dermatitis Completed NCT00666159 Phase 4
23 Comparison Study Between Protopic (Tacrolimus Ointment) and Elidel (Pimecrolimus Cream) in Pediatric Patients With Mild Atopic Dermatitis Completed NCT00667160 Phase 4
24 Measuring Adherence to Topical Therapy in Children With Atopic Dermatitis and the Impact of a Return Visit Completed NCT00654355 Phase 4
25 Study of the Safety and Efficacy of Tacrolimus Ointment in Treating Chronic Allergic Contact Dermatitis Completed NCT00667056 Phase 4
26 Efficacy of Desonide (Desonatetm) Gel 0.05% in Younger and Older Subjects With Atopic Dermatitis Completed NCT00690833 Phase 4
27 An Efficacy and Safety Study of Tacrolimus Ointment in Adult Participants With Atopic Dermatitis Completed NCT01828879 Phase 4
28 An Efficacy and Safety Study of Tacrolimus Ointment in Pediatric Participants With Atopic Dermatitis Completed NCT01782729 Phase 4
29 Pimecrolimus Cream 1% (Elidel®) and Medicated Device Cream (EletoneTM) in the Treatment and Maintenance of Atopic Dermatitis. Completed NCT01177566 Phase 4
30 Epiceram Versus Elidel for Treatment of Mild to Moderate Atopic Dermatitis Completed NCT00460083 Phase 4
31 Pimecrolimus Cream 1% Plus Topical Corticosteroid in Patients (2-17 Years of Age) With Severe Atopic Dermatitis Completed NCT00121381 Phase 4
32 Evaluation of Cetaphil Advanced Usage to Control Light to Moderate Atopic Dermatitis, in Attempt to Reduce the Necessity of Topic Corticoids Application Completed NCT01063218 Phase 4
33 Management of Pruritus With Xyzal in Atopic Dermatitis Completed NCT00884325 Phase 4
34 Efficacy and Safety of Pimecrolimus Cream 1% in Patients (2 to 11 Years Old) With Mild to Moderate Facial Atopic Dermatitis Completed NCT00130364 Phase 4
35 Proactive Treatment of Tacrolimus Ointment for Adult Facial Seborrheic Dermatitis Completed NCT01591070 Phase 4
36 Analysis of the Quality of Life, the Clinical Effectiveness and Cost-effectiveness of a Novel Educational Programme in Patients With Psoriasis and Atopic Dermatitis Completed NCT01077882 Phase 4
37 Locobase® REPAIR Used as an Adjunctive to Standard Therapy in Children With Moderate to Severe Atopic Dermatitis Completed NCT00673725 Phase 4
38 A Multi-Center Study of Short and Long-term Use of Protopic Ointment in Patients With Atopic Dermatitis Completed NCT00106496 Phase 4
39 Ethanol-Free Clobetasol Propionate Foam 0.05% (Olux-E Foam) vs Vehicle Foam in the Treatment of Chronic Hand Dermatitis. Completed NCT01323673 Phase 4
40 Combination Therapy for Atopic Dermatitis Completed NCT00119158 Phase 4
41 Study to Determine the Effect of an Anti-IgE Agent on Inflammatory Cells in the Skin of Atopic Dermatitis Patients Completed NCT00822783 Phase 4
42 A Study to Investigate the Use of Hydrogel Vehicle in Maintaining the Skin Barrier in Persons With Atopic Dermatitis Completed NCT01065714 Phase 4
43 Trial on Effectiveness Combined Probiotics in Atopic Dermatitis in Children Completed NCT02519556 Phase 4
44 Safety and Efficacy of Pimecrolimus Cream 1% in Mild to Moderate Head and Neck Atopic Dermatitis (AD) Patients Completed NCT00121316 Phase 4
45 Preventive Treatment of Tacrolimus Ointment in Children With Atopic Dermatitis Completed NCT01745159 Phase 4
46 Cetaphil Restoraderm Effect on Young Children With Atopic Dermatitis Completed NCT02589392 Phase 4
47 The Impact of Treating Staphylococcus Aureus Infection and Colonization on the Clinical Severity of Atopic Dermatitis Completed NCT00179959 Phase 4
48 Comparison of the Efficacy and Safety of Two Topical Creams for Pediatric Atopic Dermatitis Completed NCT00828412 Phase 4
49 STUDY TO ASSESS THE LONG-TERM SAFETY OF EXTINA (KETOCONAZOLE) FOAM, 2% Completed NCT00703846 Phase 4
50 Efficacy and Safety Study of Advantan for Maintenance Treatment of Atopic Dermatitis Completed NCT00185510 Phase 4

Search NIH Clinical Center for Dermatitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: dermatitis

Sources

Genetic Tests for Dermatitis

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Genetic tests related to Dermatitis:

id Genetic test Affiliating Genes
1 Eczema 29
Sources

Anatomical Context for Dermatitis

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MalaCards organs/tissues related to Dermatitis:

39
Skin, T Cells, Testes, Neutrophil, Monocytes, Colon, Liver
Sources

Publications for Dermatitis

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Articles related to Dermatitis:

(show top 50) (show all 5184)
id Title Authors Year
1
Altered Expression of Genes Encoding Cornulin and Repetin in Atopic Dermatitis. ( 28219068 )
2017
2
Mother Nature in Eczema: Maternal Factors Influencing Atopic Dermatitis. ( 28523877 )
2017
3
Low-dose oral isotretinoin for moderate to severe seborrhea and seborrheic dermatitis: a randomized comparative trial. ( 27778328 )
2017
4
Successful treatment of lichen amyloidosis accompanied by atopic dermatitis by fractional CO2 laser. ( 28535110 )
2017
5
Atopic Dermatitis and Allergic Urticaria: Cutaneous Manifestations of Immunodeficiency. ( 27886899 )
2017
6
CD8+ T-cell-mediated Interface Dermatitis after CCR4+ T-cell Depletion by Mogamulizumab Treatment of Adult T-cell Leukaemia/lymphoma. ( 27786349 )
2017
7
Diagnosis and management of allergic contact dermatitis in children: common allergens that can be easily missed. ( 28525402 )
2017
8
Atopic dermatitis: immune deviation, barrier dysfunction, IgE autoreactivity and new therapies. ( 28057434 )
2017
9
Wet Wipe Allergens: Retrospective Analysis From the North American Contact Dermatitis Group 2011-2014. ( 28002231 )
2017
10
Serum levels and tissue expression of interleukin-31 in dermatitis herpetiformis and bullous pemphigoid. ( 28465041 )
2017
11
Correlation Between Socioeconomic Status and Atopic Dermatitis in Korean Adults: The Korea National Health and Nutrition Examination Survey (2007-2014). ( 28516452 )
2017
12
Efficacy of hospital inpatient topical treatment for severe adult atopic dermatitis: a retrospective study of 56 patients. ( 28524058 )
2017
13
Weissella cibaria WIKIM28 ameliorates atopic dermatitis-like skin lesions by inducing tolerogenic dendritic cells and regulatory T cells in BALB/c mice. ( 28067304 )
2017
14
Staphylococcus aureus colonization isA associated with increased inhaled corticosteroid requirements in patients with atopic dermatitis and asthma. ( 28526276 )
2017
15
The histopathologic features of autoimmune progesterone dermatitis. ( 27766657 )
2017
16
Preliminary evaluation of cytosine-phosphate-guanine oligodeoxynucleotides bound to gelatine nanoparticles as immunotherapy for canine atopic dermatitis. ( 28526774 )
2017
17
The Natural Course of Atopic Dermatitis and the Association with Asthma. ( 28063089 )
2017
18
Immunomodulatory effects of Pseudostellaria heterophylla (Miquel) Pax on regulation of Th1/Th2 levels in mice with atopic dermatitis. ( 28035398 )
2017
19
Evidence of regulatory myeloid dendritic cells and circulating inflammatory epidermal dendritic cells-like modulated by Toll-like receptors 2 and 7/8 in adults with atopic dermatitis. ( 28083892 )
2017
20
Clinical features of shiitake dermatitis: a systematic review. ( 28054338 )
2017
21
Case Series Study of the Efficacy of Compounded Antibacterial, Steroid, and Moisturizer in Atopic Dermatitis. ( 28523898 )
2017
22
CD1c+ Blood Dendritic Cells in Atopic Dermatitis are Premature and Can Produce Disease-specific Chemokines. ( 27701668 )
2017
23
Allergic Contact Dermatitis to 3-o-Ethyl-L-Ascorbic Acid in Skin-lightening Cosmetics. ( 28002235 )
2017
24
Extract of Polygala tenuifolia Alleviates Stress-Exacerbated Atopy-Like Skin Dermatitis through the Modulation of Protein Kinase A and p38 Mitogen-Activated Protein Kinase Signaling Pathway. ( 28106783 )
2017
25
Targeted Treatment of Atopic Dermatitis. ( 28528610 )
2017
26
Difficult to Manage Atopic Dermatitis. ( 28065338 )
2017
27
Atopic dermatitis in adults: a diagnostic challenge. ( 28071589 )
2017
28
Occupational allergic contact dermatitis caused by benzisothiazolinone in printing ink and soap. ( 27957753 )
2017
29
Dietary modifications in atopic dermatitis: patient-reported outcomes. ( 28043181 )
2017
30
High-frequency ultrasound quantification of acute radiation dermatitis: pilot study of patients undergoing radiotherapy for breast cancer. ( 28513053 )
2017
31
Prevalence of filaggrin gene mutations in patients with atopic dermatitis and ichthyosis vulgaris in Kyushu area of Japan and South Korea. ( 28143684 )
2017
32
Atopic dermatitis: Burden of illness, quality of life, and associated complications. ( 28052794 )
2017
33
Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype. ( 27304082 )
2017
34
Expression of keratin 1, keratin 10, desmoglein 1 and desmocollin 1 in the epidermis: possible downregulation by interleukin-4 and interleukin-13 in atopic dermatitis. ( 28524044 )
2017
35
Phenotypes of Atopic Dermatitis Depending on the Timing of Onset and Progression in Childhood. ( 28531273 )
2017
36
Allergic contact dermatitis caused by exfoliating socks. ( 27957756 )
2017
37
Autoimmune progesterone dermatitis manifesting as mucosal erythema multiforme in the setting of HIV infection. ( 28050592 )
2017
38
Allergic Contact Dermatitis Due to Methylisothiazolinone in a Young Girl's Laundry Detergent. ( 28523864 )
2017
39
Skin pH and Transepidermal Water Loss Values in Children with Diaper Dermatitis in Ibadan, Nigeria. ( 28523895 )
2017
40
Stasis Dermatitis: Pathophysiology, Evaluation, and Management. ( 28063094 )
2017
41
Occupational allergic contact dermatitis caused by tetracaine in an otorhinolaryngologist. ( 27957755 )
2017
42
The nutrition of poultry as a factor affecting litter quality and foot pad dermatitis - an updated review. ( 28066939 )
2017
43
A Mouse Model for Atopic Dermatitis Using Topical Application of Vitamin D3 or of Its Analog MC903. ( 28063040 )
2017
44
Tofacitinib citrate for the treatment of refractory, severe chronic actinic dermatitis. ( 28050588 )
2017
45
Association of atopic dermatitis with depressive symptoms and suicidal behaviors among adolescents in Korea: the 2013 Korean Youth Risk Behavior Survey. ( 28049449 )
2017
46
Occupational Allergic Contact Dermatitis due to Multiple Tropical Plant Species. ( 28529083 )
2017
47
Non-invasive evaluation of atopic dermatitis based on redox status using in vivo dynamic nuclear polarization magnetic resonance imaging. ( 28041828 )
2017
48
Filaggrin Mutation in Korean Patients with Atopic Dermatitis. ( 28120571 )
2017
49
Allergic contact dermatitis caused by efinaconazole: positive patch test reactions up to 0.1% pet. ( 27957750 )
2017
50
Patch Test Reactions to Corticosteroids: Retrospective Analysis From the North American Contact Dermatitis Group 2007-2014. ( 28002236 )
2017
Sources

Variations for Dermatitis

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Sources

Expression for Dermatitis

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Search GEO for disease gene expression data for Dermatitis.
Sources

Pathways for Dermatitis

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Pathways related to Dermatitis according to GeneCards Suite gene sharing:

(show all 24)
id Super pathways Score Top Affiliating Genes
1
PEDF Induced Signaling 60
Show member pathways
 13.57 CCL11 CCL17 CCL22 CCL27 IFNG IL13
2
TGF-Beta Pathway 60
Show member pathways
 13.45 CCL11 CCL17 CCL22 CCL27 IFNG IL13
3
Akt Signaling 60
Show member pathways
 13.31 CCL11 CCL17 CCL22 CCL27 IL13 IL4
4
Cytokine Signaling in Immune system 62
Show member pathways
 13.29 CCL11 CCL22 IFNG IGHE IL13 IL31
5
PAK Pathway 60
Show member pathways
 13.2 CCL11 CCL17 CCL22 CCL27 IL13 IL4
6
Allograft rejection 1 37
Show member pathways
 12.74 CCL11 IFNG IL13 IL4 IL5
7
IL-17 Family Signaling Pathways 61
Show member pathways
 12.27 CCL11 CCL17 IFNG IL13 IL4 IL5
8
Jak-STAT signaling pathway (KEGG) 37
Show member pathways
 12.15 IFNG IL13 IL4 IL5 TSLP
9
Immune response IFN alpha/beta signaling pathway 21
Show member pathways
 12.08 IFNG IL13 IL4 IL5
10
Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions 61
Show member pathways
 11.95 CCL11 CCL17 CCL22 CCL27
11
Interleukin-4 and 13 signaling 62
11.93 CCL11 CCL22 IGHE IL13 IL4
12
Glucocorticoid receptor regulatory network 1
11.75 IFNG IL13 IL4 IL5
13
Innate Lymphoid Cell Differentiation Pathways 61
11.67 IFNG IL13 IL4 IL5 TSLP
14
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 1
Show member pathways
 11.66 IFNG IL4 IL5
15
IL4-mediated signaling events 1
11.52 CCL11 CCL17 IGHE IL4 IL5
16
Lung fibrosis 1
11.45 CCL11 CMA1 IL13 IL4 IL5
17
Interleukin-10 signaling 62
11.44 CCL22 IL13 IL4
18
Inflammatory Response Pathway 1
11.24 IFNG IL4 IL5
19
Cytokines and Inflammatory Response 1
11.21 IFNG IL13 IL4 IL5
20
OX40 Pathway 60
11.12 IFNG IL13 IL4 IL5
21
G-protein signaling_RhoB regulation pathway 21
10.93 CCL11 CCL17 CCL22 CCL27 IL13 IL4
22
Th2 Differentiation Pathway 61
10.9 CCL11 CCL17 CCL22 IFNG IL13 IL31
23
Development and heterogeneity of the ILC family 1
10.86 IFNG IL13 IL4 IL5 TSLP
24
IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types 61
10.85 IL13 IL4 IL5
Sources

GO Terms for Dermatitis

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Cellular components related to Dermatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.7 CCL11 CCL17 CCL22 CCL27 IFNG IL13
2 external side of plasma membrane GO:0009897 9.55 IFNG IGHE IL13 IL31RA IL4
3 extracellular region GO:0005576 9.47 CCL11 CCL17 CCL22 CCL27 CMA1 FAF2

Biological processes related to Dermatitis according to GeneCards Suite gene sharing:

(show all 25)
id Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.92 CCL17 CCL22 CCL27 IL13
2 inflammatory response GO:0006954 9.89 CCL11 CCL17 CCL22 IL13 IL5
3 cellular response to tumor necrosis factor GO:0071356 9.8 CCL11 CCL17 CCL22
4 response to virus GO:0009615 9.79 CCL11 CCL22 IFNG
5 cellular response to interleukin-1 GO:0071347 9.77 CCL11 CCL17 CCL22
6 chemokine-mediated signaling pathway GO:0070098 9.73 CCL11 CCL17 CCL22
7 cellular response to interferon-gamma GO:0071346 9.71 CCL11 CCL17 CCL22
8 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.65 IFNG IL31RA IL4
9 monocyte chemotaxis GO:0002548 9.63 CCL11 CCL17 CCL22
10 positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 9.61 IL31RA IL4
11 microglial cell activation GO:0001774 9.6 IL13 IL4
12 positive regulation of chemokine biosynthetic process GO:0045080 9.58 IFNG IL4
13 positive regulation of isotype switching to IgG isotypes GO:0048304 9.58 IFNG IL4
14 positive regulation of B cell proliferation GO:0030890 9.58 IL13 IL4 IL5
15 positive regulation of mast cell degranulation GO:0043306 9.57 IL13 IL4
16 positive regulation of MHC class II biosynthetic process GO:0045348 9.55 IFNG IL4
17 negative regulation of macrophage activation GO:0043031 9.52 IL31RA IL4
18 positive regulation of immunoglobulin production GO:0002639 9.51 IL13 IL4
19 neutrophil chemotaxis GO:0030593 9.46 CCL11 CCL17 CCL22 IFNG
20 regulation of proton transport GO:0010155 9.43 IL13 IL4
21 lymphocyte chemotaxis GO:0048247 9.43 CCL11 CCL17 CCL22
22 negative regulation of complement-dependent cytotoxicity GO:1903660 9.37 IL13 IL4
23 chemotaxis GO:0006935 9.35 CCL11 CCL17 CCL22 CCL27 IL4
24 T-helper 2 cell cytokine production GO:0035745 9.32 IL31RA IL4
25 immune response GO:0006955 9.28 CCL11 CCL17 CCL22 CCL27 IFNG IGHE

Molecular functions related to Dermatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 CCR chemokine receptor binding GO:0048020 9.33 CCL11 CCL17 CCL22
2 cytokine activity GO:0005125 9.28 CCL11 CCL17 CCL22 IFNG IL13 IL31
3 CCR3 chemokine receptor binding GO:0031728 9.26 CCL11 CCL27
4 chemokine activity GO:0008009 9.26 CCL11 CCL17 CCL22 CCL27
Sources

Sources for Dermatitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
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31 HMDB
32 HPO
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The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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