Dermatitis disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Summaries for Dermatitis

Sources:
⁶⁴Wikipedia, ³²MalaCards
See all sources

Wikipedia:⁶⁴ Dermatitis (from Greek ????? derma \"skin\" and -???? -itis \"inflammation\") or eczema (Greek: ??????... more...

MalaCards based summary: Dermatitis, also known as skin inflammation nos, is related to contact dermatitis and atopic dermatitis. An important gene associated with Dermatitis is CCL11 (chemokine (C-C motif) ligand 11), and among its related pathways are OX40 Pathway and Cytokines and Inflammatory Response. The drugs clobetasol and cod liver oil and the compounds salmeterol and histamine dihydrochloride have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and testes, and related mouse phenotypes are hematopoietic system and immune system.

Aliases & Classifications for Dermatitis

Sources:
⁹Disease Ontology, ¹¹DISEASES, ⁴⁴Novoseek, ⁶¹UMLS, ⁵⁶SNOMED-CT, ³⁴MeSH, ³⁹NCIt
See all sources

Dermatitis, Aliases & Descriptions:

Name: Dermatitis ⁹ ¹¹ ⁴⁴ ⁶¹

Skin Inflammation Nos ⁹

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases

External Ids:

Disease Ontology⁹ DOID:2723

MeSH³⁴ D003872

SNOMED-CT⁵⁶ 182782007, 4979002, 156388001 156358005, 200884006, 267847004, 267856007, 43116000, 238538009, more

NCIt³⁹ C2983

UMLS⁶¹ C0011603

Related Diseases for Dermatitis

Sources:
¹⁸GeneCards, ¹⁹GeneDecks
See all sources

Diseases related to Dermatitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50) (show all 622)

id	Related Disease	Score	Top Affiliating Genes
1	contact dermatitis	32.6	FLG
2	atopic dermatitis	32.1	HRH1, KLK7, IL13, FLG, CCL11, CCL27
3	allergic contact dermatitis	31.8	FLG, CXCR3, CCR4, CCL27, IL5
4	asthma	31.4	IL13, CCL11
5	eczema herpeticum	31.4	IGHE
6	folliculitis	31.1	CCL11
7	conjunctivitis	31.0	IGHE, HRH1
8	cutaneous t cell lymphoma	30.9	IL5, CCR4, CXCR3
9	food allergy	30.8	IGHE, CCL11, IL5, IL13
10	lichen planus	30.8	CXCR3, FLG
11	egg allergy	30.7	IGHE, IL5
12	psoriasis	30.7	FLG, CXCR3, CCR4, CCL11, CCL27, IL5
13	keratoconjunctivitis	30.7	CCL11, IL5, IL13
14	bullous pemphigoid	30.7	IGHE, FLG, CCL11, IL5, IL13
15	atopy	30.6	IGHE, FLG, CXCR3, CCL11, IL5, IL13
16	netherton syndrome	30.6	IGHE, KLK7
17	mycosis fungoides	30.5	CXCR3, CCR4, CCL27, IL5
18	malaria	30.5	HRH1
19	bronchitis	30.4	IGHE, CCL11, IL5
20	angioedema	30.4	HRH1, IL5, IGHE
21	rhinitis	30.4	IGHE, CCL11, IL5, IL13, HRH1
22	cutaneous leishmaniasis	30.4	IL5, IL13
23	sarcoidosis	30.3	CXCR3, CCR4, CCL11, IL13
24	eosinophilic gastroenteritis	30.3	IL5, CCL11, IGHE
25	eosinophilia	30.3	IGHE, CCR4, CCL11, CCL27, IL5, IL13
26	schistosomiasis	30.2	IL13, IL5, IGHE
27	skin disease	30.2	CCL11, CCL27, IL5, IL13, KLK7, HRH1
28	leishmaniasis	30.2	IL13, IL5
29	rheumatoid arthritis	30.2	FLG, CXCR3, CCR4, CCL11, CCL27, IL13
30	strongyloidiasis	30.2	IL5, IGHE
31	mastocytosis	30.1	IGHE, IL5, IL13
32	allergic bronchopulmonary aspergillosis	30.1	IL5, IGHE
33	allergic rhinitis	30.1	IGHE, CCL11, IL5, IL13, HRH1
34	hypereosinophilic syndrome	30.1	IGHE, CCL11, IL5
35	uveitis	30.0	CCL11, CCR4, CXCR3
36	chronic obstructive pulmonary disease	30.0	IL13, CCL11, CCR4, CXCR3
37	otitis media	30.0	CCL11, IGHE
38	respiratory failure	30.0	IGHE, CCL11, IL13
39	pneumonia	29.9	CCL11, IL5, IL13, HRH1
40	allergic conjunctivitis	29.9	IGHE, CCL11, IL5, IL13, HRH1
41	helminthiasis	29.9	IL13, IL5, IGHE
42	allergic asthma	29.9	IGHE, FLG, CCR4, CCL11, IL5, IL13
43	pulmonary fibrosis	29.8	CXCR3, CCR4, IL13
44	vernal keratoconjunctivitis	29.6	IGHE, CXCR3, CCL11, IL5, IL13
45	ipex syndrome	29.6	IGHE, CXCR3, CCR4, CCL11, CCL27
46	multiple sclerosis	29.4	IL13, IL5, CCL27, CCL11, CCR4, CXCR3
47	dermatitis herpetiformis	11.1
48	exfoliative dermatitis	10.9
49	occupational dermatitis	10.9
50	granulomatous dermatitis	10.8

Graphical network of the top 20 diseases related to Dermatitis:

Symptoms for Dermatitis

Drugs & Therapeutics for Dermatitis

Sources:
⁴¹NIH Clinical Center, ⁶ClinicalTrials, ⁶¹UMLS, ⁴⁰NDF-RT
See all sources

Drug clinical trials:

Search ClinicalTrials for Dermatitis

Search NIH Clinical Center for Dermatitis

Inferred drug relations via UMLS⁶¹/NDF-RT⁴⁰:

Show with subtypes

Genetic Tests for Dermatitis

Anatomical Context for Dermatitis

Sources:
³²MalaCards
See all sources

MalaCards organs/tissues related to Dermatitis:

³²

Skin, T cells, Testes, Neutrophil, Monocytes, Colon, Liver, Thyroid, Breast, Thymus, B cells, Endothelial, Bone, Eye, Small intestine, Lung, Whole blood, Heart, Tongue, Lymph node, Spinal cord, Tonsil, Myeloid, Pituitary, Bone marrow, Brain, Kidney, Nk cells, Appendix, Pancreatic islet

Animal Models for Dermatitis or affiliated genes

Sources:
³⁶MGI
See all sources

MGI Mouse Phenotypes related to Dermatitis:

³⁶

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	hematopoietic system phenotype	MP:0005397	8.6	FLG, CXCR3, CCR4, CCL11, IL5, IL13
2	immune system phenotype	MP:0005387	8.1	HRH1, IGHE, FLG, ADH5, CXCR3, CCR4

Publications for Dermatitis

Sources:
⁵¹PubMed
See all sources

Articles related to Dermatitis:

(show top 50) (show all 4540)

id	Title	Authors	Year
1	Cases of occupational dermatitis and asthma in beauticians that were reported to The Health and Occupation Research (THOR) network from 1996 to 2011. (24934913)	Kwok C.... Wilkinson M.	2014
2	Human I^-defensin-2 as a marker for disease severity and skin barrier properties in atopic dermatitis. (23647067)	Clausen M.L.... Agner T.	2013
3	Inhibitory effects of Juglans mandshurica leaf on allergic dermatitis-like skin lesions-induced by 2,4-dinitrochlorobenzene in mice. (24252297)	Park G.... Oh M.S.	2013
4	IL-17 expression in dermatitis herpetiformis and bullous pemphigoid. (23970818)	Zebrowska A.... Waszczykowska E.	2013
5	Effects of Korean red ginseng extract on the prevention of atopic dermatitis and its mechanism on early lesions in a murine model. (23149290)	Cho E.... Cho S.H.	2013
6	Serum visfatin levels in patients with atopic dermatitis and cutaneous T-cell lymphoma. (24001451)	Suga H.... Sato S.	2013
7	Laser Recall Dermatitis. (24336981)	CA^rdoba S.... Borbujo J.	2013
8	Allergic contact dermatitis due to epsilon-aminocaproic acid: a case report and mini-review of the published work. (23398202)	Yamamoto Y.... Katoh N.	2013
9	Skin-specific expression of IL-33 activates group 2 innate lymphoid cells and elicits atopic dermatitis-like inflammation in mice. (23918359)	Imai Y.... Yamanishi K.	2013
10	A field trial of infrared thermography as a non-invasive diagnostic tool for early detection of digital dermatitis in dairy cows. (24389042)	Alsaaod M.... STEINER A.	2013
11	Allergic contact dermatitis caused by Hedera helix arborescens and not by Hedera helix L. (22568849)	Lurquin E.... Goossens A.	2012
12	Effect of bathing on atopic dermatitis during the summer season. (23130333)	Kim H.... Kim J.	2012
13	Impact of interactive web-based education with mobile and email-based support of general practitioners on treatment and referral patterns of patients with atopic dermatitis: randomized controlled trial. (23249479)	Schopf T.... Flytkjaer V.	2012
14	Management of dermatitis herpetiformis. (22560140)	Cardones A.R.... Hall R.P.	2012
15	Interstitial granulomatous dermatitis? An unusual presentation in the mucosa and periungual skin. (21352283)	Nakamura N.... Katoh N.	2011
16	Allergic contact dermatitis following ocular use of corticosteroids. (21265627)	Baeck M.... Goossens A.	2011
17	Acute haemorrhagic conjunctivitis epidemics and outbreaks of Paederus spp. keratoconjunctivitis ('Nairobi red eyes') and dermatitis. (21920128)	Mbonile L.	2011
18	Kaposi's sarcoma in an atopic dermatitis patient: a case report and a review of literature. (21385206)	Salem H.A.... Abd El Gawad M.	2011
19	Systemic allergic contact dermatitis to black cumin essential oil expressing as generalized erythema multiforme. (21524993)	Nosbaum A.... BAcrard F.	2011
20	Allergic contact dermatitis from N,N-methylenebismorpholine in a cutting oil. (20920419)	Field S.... Bourke J.F.	2010
21	In vitro profiling of pramiconazole and in vivo evaluation in Microsporum canis dermatitis and Candida albicans vaginitis laboratory models. (20805398)	de Wit K.... Maes L.	2010
22	Number of flocks on the same litter and carcase condemnations due to cellulitis, arthritis and contact foot-pad dermatitis in broilers. (21058060)	Xavier D.B.... Bernal F.E.	2010
23	A rare case of allergic contact dermatitis from silver nitrate in a widely used special patch test marker. (19706054)	Ozkaya E.	2009
24	Generalized erythema multiforme after localized allergic dermatitis from dark henna tattoo. (19689544)	Neri I.... Patrizi A.	2009
25	Contact irritant dermatitis from insect secretions: report of 74 cases in a military unit in Eritrea. (19731793)	Smadi R.M.... Ka'abneh A.	2009
26	Defective killing of Staphylococcus aureus in atopic dermatitis is associated with reduced mobilization of human beta-defensin-3. (18538383)	Kisich K.O.... Leung D.Y.	2008
27	Bartonella-associated meningoradiculoneuritis and dermatitis or panniculitis in 3 dogs. (18466250)	Cross J.R.... Duncan R.B.	2008
28	Occupational dermatitis in a hairdresser. (17717371)	Worth A.... Sheikh A.	2007
29	Deficiency of dermcidin-derived antimicrobial peptides in sweat of patients with atopic dermatitis correlates with an impaired innate defense of human skin in vivo. (15944307)	Rieg S.... Schittek B.	2005
30	Inflammatory mediators in patients with atopic dermatitis after treatment with transfer factor]. (15491080)	Orozco T.T.... Parra S.E.	2004
31	Effect of staphylococcal enterotoxin B on specific antibody production in children with atopic dermatitis. (12635580)	Sohn M.H.... Kim K.E.	2003
32	Soluble E-selectin correlates with disease activity in cyclosporin A-treated patients with atopic dermatitis. (10195358)	KAogi M.K.... WA1thrich B.	1999
33	Tissue transglutaminase antibodies in dermatitis herpetiformis. (10490368)	Porter W.M.... Fry L.	1999
34	Acute inflammatory demyelinating polyradiculoneuropathy associated with hyperIgEemia and atopic dermatitis. (9562273)	Ikeda K.... Segawa F.	1998
35	Occupational dermatitis due to formaldehyde in newspaper. (9330824)	Sanchez I.... Martin-Gil D.	1997
36	Resolution of exfoliative dermatitis and Malassezia pachydermatis overgrowth in a cat after surgical thymoma resection. (9358405)	Forster-Van Hijfte M.A.... White R.N.	1997
37	Chronic actinic dermatitis. An immunohistochemical study of its T-cell antigenic profile, with comparison to cutaneous T-cell lymphoma. (7802165)	Heller P.... Lim H.W.	1994
38	The histopathologic spectrum of palisaded neutrophilic and granulomatous dermatitis in patients with collagen vascular disease. (7944509)	Chu P.... LeBoit P.E.	1994
39	Systemic interferon gamma treatment in severe atopic dermatitis. (8315079)	Reinhold U.... Kreysel H.W.	1993
40	Photosensitivity dermatitis and actinic reticuloid syndrome (chronic actinic dermatitis). (2203443)	Ferguson J.	1990
41	Manic depression induced by dapsone in patient with dermatitis herpetiformis. (2510873)	Gawkrodger D.	1989
42	Occupational dermatitis to Ampholyt G in hospital personnel. (6222878)	Foussereau J.... Hecht M.T.	1983
43	Video computer terminals and occupational dermatitis. (6458886)	LindAcn V.... Rolfsen S.	1981
44	Cercarial dermatitis. (4412365)	Hoeffler D.F.	1974
45	Exfoliative dermatitis and generalized erythroderma. (4257634)	Everett M.A.	1969
46	Hypothermia in patients with exfoliative dermatitis. (13754513)	KROOK G.	1960
47	Allergic occupational dermatitis. (13336265)	SCHWARTZ L.	1956
48	Exfoliative dermatitis after undecylenic acid therapy for psoriasis. (14774148)	SCHIFF B.L.	1950
49	Exfoliative dermatitis; classification, diagnosis and treatment. (20252104)	KIERLAND R.R.	1947
50	Exfoliative dermatitis following penicillin therapy. (20999603)	NOLAN D.E.... PEDIGO G.W.	1946

Genes related to Dermatitis

Sources:
¹⁸GeneCards, ¹antibodies-online, ⁴⁵Novus Biologicals
See all sources

Genes related to Dermatitis:

(show all 25)

- Elite gene

id	Symbol	Description	Score	Implication
1	CCL11	chemokine (C-C motif) ligand 11	20.45	GeneCards inferred via : Publications, Disorders, Summaries (show sections)
2	ZNF750	zinc finger protein 750	19.64	GeneCards inferred via : Publications, Disorders, Summaries (show sections)
3	KLK7	kallikrein-related peptidase 7	18.84	GeneCards inferred via : Publications, Disorders, Summaries (show sections)
4	ADH5	alcohol dehydrogenase 5 (class III), chi polypeptide	18.04	GeneCards inferred via : Summaries (show sections)
5	FLG	filaggrin	17.20	GeneCards inferred via : Publications, Disorders (show sections)
6	IL5	interleukin 5 (colony-stimulating factor, eosinophil)	16.40	GeneCards inferred via : Publications, Disorders (show sections)
7	CXCR3	chemokine (C-X-C motif) receptor 3	15.59	GeneCards inferred via : Publications, Disorders (show sections)
8	IL13	interleukin 13	14.79	GeneCards inferred via : Publications, Disorders (show sections)
9	FAF2	Fas associated factor family member 2	14.11	GeneCards inferred via : Publications, Gene name, Summaries (show sections)
10	HRH1	histamine receptor H1	13.24	GeneCards inferred via : Disorders, Summaries (show sections)
11	NACA	nascent polypeptide-associated complex alpha subunit	12.44	GeneCards inferred via : Publications, Summaries (show sections)
12	DHX34	DEAH (Asp-Glu-Ala-His) box polypeptide 34	11.64	GeneCards inferred via : Summaries (show sections)
13	DHX8	DEAH (Asp-Glu-Ala-His) box polypeptide 8	10.84	GeneCards inferred via : Summaries (show sections)
14	ATOD3	Dermatitis, atopic, 3	10.04	GeneCards inferred via : Publications, Gene name (show sections)
15	ATOD5	Dermatitis, atopic, 5	9.24	GeneCards inferred via : Publications, Gene name (show sections)
16	ATOD6	Dermatitis, atopic, 6	8.44	GeneCards inferred via : Publications, Gene name (show sections)
17	ATOD7	Dermatitis, atopic, susceptibility to, 7	7.63	GeneCards inferred via : Gene name (show sections)
18	CCR4	chemokine (C-C motif) receptor 4	6.80	GeneCards inferred via : Publications, Disorders (show sections)
19	CCL27	chemokine (C-C motif) ligand 27	5.99	GeneCards inferred via : Publications, Disorders (show sections)
20	IGHE	immunoglobulin heavy constant epsilon	5.19	GeneCards inferred via : Publications, Disorders (show sections)
21	IFNG	interferon, gamma	4.39	GeneCards inferred via : Publications, Disorders (show sections)
22	SELE	selectin E	3.59	GeneCards inferred via : Publications, Disorders (show sections)
23	IL17A	interleukin 17A	2.79	GeneCards inferred via : Publications, Disorders (show sections)
24	ICAM1	intercellular adhesion molecule 1	1.99	GeneCards inferred via : Publications, Disorders (show sections)
25	IL1A	interleukin 1, alpha	1.19	GeneCards inferred via : Publications, Disorders (show sections)

Products for genes related to Dermatitis disease:

id	Company	Proteins	Lysates	Antibodies	Kits and Assays
1	Antibodies-online	18	-	20	20
2	Novus Biologicals	17	16	21	-

Variations for Dermatitis

Expression for genes affiliated with Dermatitis

Sources:
²BioGPS, ¹⁶Gene Expression Omnibus DataSets
See all sources

Expression patterns in normal tissues for genes affiliated with Dermatitis

Search GEO for disease gene expression data for Dermatitis.

Pathways for genes affiliated with Dermatitis

Sources:
⁴⁹PathCards, ⁵²QIAGEN, ³⁷NCBI BioSystems Database, ⁵³R&D Systems, ³⁰KEGG, ⁵⁴Reactome
See all sources

Pathways related to Dermatitis according to GeneCards/GeneDecks:

(show all 12)

id	Super pathways (with members indented)	Score	Top Affiliating Genes
1	OX40 Pathway⁵²	10.1	IL13, IL5
2	Cytokines and Inflammatory Response³⁷	10.1	IL5, IL13
3	IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types⁵³	10.1	IL13, IL5
4	IL4-mediated signaling events³⁷	9.7	IL5, CCL11, IGHE
5	Chemokine Signaling⁵² Show member pathways Chemokine signaling pathway³⁰	9.4	CXCR3, CCR4, CCL11, CCL27
6	Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions⁵³ Show member pathways Chemokine receptors bind chemokines⁵⁴	9.4	CCL27, CCL11, CCR4, CXCR3
7	Integrin Pathway⁵² Show member pathways Inhibition of Angiogenesis by TSP1⁵² Transendothelial Migration of Leukocytes⁵² FAK1 Signaling⁵² GnRH Signaling⁵² UPA-UPAR Pathway⁵²	9.4	CCL27, CCL11, CCR4, CXCR3
8	Peptide ligand-binding receptors⁵⁴ Show member pathways Vasopressin-like receptors⁵⁴ Relaxin receptors⁵⁴ Formyl peptide receptors bind formyl peptides and many other ligands⁵⁴ GPCRs, Class A Rhodopsin-like³⁷ Class A/1 (Rhodopsin-like receptors)⁵⁴ GPCR ligand binding⁵⁴ Neuroactive ligand-receptor interaction³⁰ G alpha (i) signalling events⁵⁴ Orexin and neuropeptides FF and QRFP bind to their respective receptors⁵⁴ Tachykinin receptors bind tachykinins⁵⁴	9.2	CXCR3, CCR4, CCL11, CCL27, HRH1
9	PEDF Induced Signaling⁵² Show member pathways all-trans-Retinoic Acid Signaling in Brain⁵² Cytokine-cytokine receptor interaction³⁰ NFAT Signaling and Lymphocyte Interactions⁵² STAT3 Pathway⁵² RAR-Gamma-RXR-Alpha Degradation⁵² PGC1Alpha Pathway⁵² Glucocorticoid Receptor Signaling⁵² IL-6 Pathway⁵² Endothelin-1 Signaling Pathway⁵² MIF Regulation of Innate Immune Cells⁵² MIF Mediated Glucocorticoid Regulation⁵²	9.0	CXCR3, CCR4, CCL11, CCL27, IL5, IL13
10	PAK Pathway⁵² Show member pathways Epithelial Adherens Junctions⁵² Antioxidant Action of Vitamin-C⁵²	9.0	IL5, CCL27, CCL11, CCR4, CXCR3, IL13
11	Akt Signaling⁵² Show member pathways p38 Signaling⁵² Tec Kinases Signaling⁵²	9.0	CXCR3, CCR4, CCL11, CCL27, IL5, IL13
12	ERK Signaling⁵² Show member pathways ILK Signaling⁵² Molecular Mechanisms of Cancer⁵² Rho Family GTPases⁵² MAPK Signaling⁵²	8.8	NACA, CXCR3, CCR4, CCL11, CCL27, IL5

Compounds for genes affiliated with Dermatitis

Sources:
⁴⁴Novoseek, ⁵⁰PharmGKB, ²⁹IUPHAR, ¹²DrugBank, ⁶⁰Tocris Bioscience, ²⁵HMDB, ³BitterDB
See all sources

Compounds related to Dermatitis according to GeneCards/GeneDecks:

(show top 50) (show all 95)

id	Compound	Score	Top Affiliating Genes
1	salmeterol⁴⁴ ⁵⁰ ²⁹ ¹²	13.2	IL5, CCL11, IL13
2	histamine dihydrochloride⁶⁰	10.2	DHX8, DHX34, HRH1
3	2-pyridylethylamine dihydrochloride⁶⁰	10.2	HRH1, DHX8, DHX34
4	mepyramine maleate⁶⁰	10.2	DHX34, DHX8, HRH1
5	clemastine fumarate⁶⁰	10.2	DHX8, HRH1, DHX34
6	ltc4⁴⁴	10.1	CCL11, IL13, IL5
7	unicap⁴⁴	10.1	IGHE, IL5, CCL11
8	ltd4⁴⁴	10.1	HRH1, IL5, IL13
9	astemizole⁴⁴ ⁶⁰ ²⁹ ¹²	13.1	HRH1, DHX8, DHX34
10	groalpha⁴⁴	10.1	IL13, CCL11, CXCR3
11	omalizumab⁴⁴ ¹²	11.1	IL5, IL13, IGHE
12	trimellitic anhydride⁴⁴	10.1	IGHE, IL13
13	anti-histamine⁴⁴	10.1	CCL11, IGHE, HRH1
14	nickel⁴⁴ ²⁵	11.1	IL13, FLG, IL5
15	oxatomide⁴⁴	10.1	HRH1, IL5, IGHE
16	ovomucoid⁴⁴	10.1	IGHE, IL13, IL5
17	praziquantel⁴⁴ ¹²	11.0	IL5, IGHE, IL13
18	nedocromil sodium⁴⁴	10.0	IGHE, IL5, HRH1
19	desloratadine⁴⁴ ¹²	11.0	IGHE, IL13, HRH1
20	methyltetrahydrophthalic anhydride⁴⁴	10.0	IL13, IGHE
21	penicillin⁴⁴	10.0	IGHE, IL5, IL13
22	sodium cromoglycate⁴⁴	9.9	HRH1, CCL11, IL5, IGHE
23	cetirizine⁴⁴ ²⁹ ²⁵ ¹²	12.9	CCL11, IGHE, HRH1, IL5
24	montelukast⁴⁴ ⁵⁰ ²⁹ ¹²	12.9	IL5, IL13, CCL11, IGHE
25	ketotifen⁴⁴ ¹²	10.9	IGHE, HRH1, IL5, CCL11
26	budesonide⁴⁴ ⁵⁰ ¹²	11.9	CCL11, IL13, IGHE, IL5
27	azelastine⁴⁴ ¹²	10.9	IL5, HRH1, IGHE
28	salbutamol⁴⁴ ⁵⁰ ²⁹ ²⁵ ¹²	13.9	CCL11, IGHE, IL13, IL5
29	fluticasone propionate⁴⁴ ⁵⁰ ⁶⁰ ¹²	12.9	IL13, IGHE, IL5, CCL11
30	pgd2⁴⁴	9.9	IL5, CCL11, IL13, IGHE
31	methacholine⁴⁴ ⁵⁰ ¹²	11.9	IL13, CCL11, IL5, IGHE
32	tacrolimus⁴⁴ ⁵⁰ ¹²	11.9	HRH1, IL13, CCL11, CXCR3, IL5
33	fmlp⁴⁴	9.7	CCL11, IL13, CXCR3, IL5
34	hydrocortisone⁴⁴ ³ ⁶⁰ ¹²	12.7	IGHE, CXCR3, IL5, IL13
35	endotoxin⁴⁴	9.7	CXCR3, HRH1, CCL11, IL13
36	ccl3⁴⁴ ²⁹	10.6	CXCR3, CCR4, CCL11, CCL27, IL13
37	ccl4⁴⁴ ²⁹	10.6	IL13, CCL27, CCR4, CXCR3, CCL11
38	prednisolone⁴⁴ ²⁹ ¹²	11.6	CCL11, IL5, IL13, IGHE, CCR4
39	indomethacin⁴⁴ ²⁹ ⁶⁰ ¹²	12.6	HRH1, IGHE, CCL11, IL5, IL13
40	histamine⁴⁴ ²⁹ ²⁵	11.5	IGHE, HRH1, IL13, CXCR3, IL5, CCL11
41	pge2⁴⁴	9.5	HRH1, CXCR3, CCL27, IL5, CCL11, IL13
42	cyclosporin a⁴⁴ ²⁹ ⁶⁰	11.4	IL13, HRH1, IGHE, IL5, CCL11
43	isoproterenol⁴⁴ ¹²	10.4	IL13, IL5, HRH1, IGHE
44	rantes⁴⁴	9.2	IL13, IL5, CCL11, CCR4, CXCR3, HRH1
45	arginine⁴⁴	9.2	IGHE, IL13, IL5, DHX8, CXCR3, ADH5
46	dexamethasone⁴⁴ ⁵⁰ ²⁹ ¹²	12.1	CCL27, CXCR3, IGHE, IL13, HRH1, IL5
47	tarc⁴⁴	9.1	CCL27, IL13, IL5, CCR4, CXCR3, IGHE
48	nitric oxide⁴⁴ ²⁵ ¹²	11.1	FLG, HRH1, CCL11, IL13, CXCR3, ADH5
49	retinoic acid⁴⁴ ²⁵	10.0	KLK7, ADH5, IL13, IL5, CCL11, CCR4
50	allergens⁴⁴	9.0	IL5, CCL27, CCL11, IL13, CXCR3, HRH1

GO Terms for genes affiliated with Dermatitis

Sources:
¹⁷Gene Ontology
See all sources

Cellular components related to Dermatitis according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	external side of plasma membrane	GO:009897	9.7	IL13, CCR4, CXCR3
2	extracellular region	GO:005576	8.7	KLK7, IL13, IL5, CCL27, CCL11, IGHE

Biological processes related to Dermatitis according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	eosinophil chemotaxis	GO:048245	10.0	HRH1, CCL11
2	response to radiation	GO:009314	10.0	CCL11, CCR4
3	positive regulation of release of sequestered calcium ion into cytosol	GO:051281	9.8	IL13, CXCR3
4	chemotaxis	GO:006935	9.4	CXCR3, CCR4, CCL11, CCL27
5	inflammatory response	GO:006954	9.3	HRH1, IL13, IL5, CCL11, CCR4, CXCR3
6	immune response	GO:006955	8.9	IGHE, CCR4, CCL11, CCL27, IL5, IL13

Molecular functions related to Dermatitis according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	chemokine receptor activity	GO:004950	9.9	CCR4, CXCR3

Products for genes affiliated with Dermatitis

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Sources for Dermatitis

¹antibodies-online

²BioGPS

³BitterDB

⁴CDC

⁵Cell Signaling Technology

⁶ClinicalTrials

⁷Clinvar

⁸dbSNP

⁹Disease Ontology

¹⁰diseasecard

¹¹DISEASES

¹²DrugBank

¹³EMD Millipore

¹⁴ExPASy

¹⁵FMA

¹⁶Gene Expression Omnibus DataSets

¹⁷Gene Ontology

¹⁸GeneCards

¹⁹GeneDecks

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²¹GeneTests

²²Genetics Home Reference

²³GTR

²⁴HGMD

²⁵HMDB

²⁶ICD10

²⁷ICD10 via Orphanet

²⁸ICD9CM

²⁹IUPHAR

³⁰KEGG

³¹LifeMap Discovery®

³²MalaCards

³³MedlinePlus

³⁴MeSH

³⁵MESH via Orphanet

³⁶MGI

³⁷NCBI BioSystems Database

³⁸NCBI Bookshelf

³⁹NCIt

⁴⁰NDF-RT

⁴¹NIH Clinical Center

⁴²NIH Rare Diseases

⁴³NINDS

⁴⁴Novoseek

⁴⁵Novus Biologicals

⁴⁶OMIM

⁴⁷OMIM via Orphanet

⁴⁸Orphanet

⁴⁹PathCards

⁵⁰PharmGKB

⁵¹PubMed

⁵²QIAGEN

⁵³R&D Systems

⁵⁴Reactome

⁵⁵SinoBiological

⁵⁶SNOMED-CT

⁵⁷SNOMED-CT via Orphanet

⁵⁸The Human Phenotype Ontology

⁵⁹Thomson Reuters

⁶⁰Tocris Bioscience

⁶¹UMLS

⁶²UMLS via Orphanet

⁶³UniProtKB/Swiss-Prot

⁶⁴Wikipedia

MCID: DRM006 MIFTS: 65	Dermatitis malady Skin diseases category
27 drugs, 25 genes, 30 tissues, 622 related diseases, clinical trials Download this MalaCard Expand all tables

Dermatitis malady