MCID: DRM006
MIFTS: 68

Dermatitis malady

Skin diseases category

Summaries for Dermatitis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Dermatitis (from Greek δέρμα derma \"skin\" and -ῖτις -itis \"inflammation\") or eczema... more...

MalaCards: Dermatitis, also known as other chronic dermatitis due to solar radiation, is related to atopic dermatitis and contact dermatitis. An important gene associated with Dermatitis is CCL11 (chemokine (C-C motif) ligand 11), and among its related pathways are Rho Family GTPases and PEDF Induced Signaling. The drugs clobetasol and cod liver oil and the compounds allergens and retinoic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and testes.

Aliases & Classifications for Dermatitis

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


Aliases & Descriptions:

dermatitis 8 10 44 60
other chronic dermatitis due to solar radiation 8
other dermatitis due to solar radiation 8
skin inflammation nos 8
dermatitis, nos 8
dermatitis nos 8


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Disease Ontology8 DOID:2723
NCIt39 C2983
MeSH34 D003872
ICD1025 L30

Related Diseases for Dermatitis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Dermatitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 550)
idRelated DiseaseScoreTop Affiliating Genes
1atopic dermatitis32.0KLK7, CCL11, CCR4, CCL27, FLG, IGHE
2contact dermatitis31.8FLG
3allergic contact dermatitis31.6CCL27
4psoriasis31.1KLK7, CCL11, CCR4, CCL27, FLG, CXCR3
5skin disease30.8KLK7, CCL11, CCL27, FLG, IGHE, CXCR3
6asthma30.8IL5, IGHE
7arthritis30.7CXCR3, FLG
8eczema herpeticum30.6IGHE
9food allergy30.5CCL11, IGHE, IL5
10urticaria30.5HRH1, IGHE
11bullous pemphigoid30.5CCL11, FLG, IGHE, IL5
12cutaneous t cell lymphoma30.4CCR4, CXCR3, IL5
13rheumatoid arthritis30.4CCL11, CCR4, CCL27, FLG, CXCR3, HRH1
14eosinophilia30.4CCL11, CCR4, CCL27, IGHE, IL5
15allergic asthma30.3CCL11, CCR4, FLG, IGHE, IL5, HRH1
16mycosis fungoides30.3IL5, CXCR3, CCL27, CCR4
17folliculitis30.2CCL11
18rhinitis30.2HRH1, IL5, IGHE, CCL11
19conjunctivitis30.2HRH1, IGHE
20keratoconjunctivitis30.2IL5, CCL11
21egg allergy30.1IGHE, IL5
22allergic rhinitis30.1CCL11, CCR4, FLG, IGHE, CXCR3, IL5
23sarcoidosis30.0CXCR3, CCR4, CCL11
24netherton syndrome30.0IGHE, KLK7
25allergic conjunctivitis29.9CCL11, IGHE, IL5, HRH1
26bronchitis29.9CCL11, IGHE, IL5
27angioedema29.9HRH1, IL5, IGHE
28eosinophilic gastroenteritis29.8CCL11, IGHE, IL5
29onchocerciasis29.8IL5
30ipex syndrome29.5CCL11, CCR4, CCL27, IGHE, CXCR3
31uveitis29.5CCL11, CCR4, CXCR3
32pulmonary eosinophilia29.5IL5, IGHE, CCL11
33pneumonia29.5HRH1, IL5, CCL11
34strongyloidiasis29.5IL5, IGHE
35otitis media29.5CCL11, IGHE
36allergic bronchopulmonary aspergillosis29.5IL5, IGHE
37churg-strauss syndrome29.5IL5
38malaria29.5HRH1
39tuberculosis29.5CXCR3, CCR4
40dermatitis herpetiformis11.1
41occupational dermatitis11.0
42irritant dermatitis10.8
43granulomatous dermatitis10.8
44cercarial dermatitis10.6
45contagious pustular dermatitis10.5
46erythema multiforme10.5
47seborrheic infantile dermatitis10.5
48celiac disease10.4
49lupus erythematosus10.4
50photoallergic dermatitis10.4

Graphical network of the top 20 diseases related to Dermatitis:



Diseases related to dermatitis

Clinical Features for Dermatitis

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Drugs & Therapeutics for Dermatitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Genetic Tests for Dermatitis

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Anatomical Context for Dermatitis

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Sources:
32MalaCards
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MalaCards organs/tissues related to Dermatitis:

32
Skin, T cells, Testes, Monocytes, Liver, Colon, Thyroid, Breast, Thymus, Endothelial, B cells, Bone, Eye, Lung, Small intestine, Whole blood, Heart, Tongue, Myeloid, Tonsil, Pituitary, Spinal cord, Pancreatic islet, Appendix, Lymph node, Brain, Kidney, Nk cells, Bone marrow

Animal Models for Dermatitis or affiliated genes

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Publications for Dermatitis

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Sources:
50PubMed
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Articles related to Dermatitis:

(show top 50)    (show all 4446)
idTitleAuthorsYear
1
Re: Incontinence-associated dermatitis: consensus statements, evidence-based guidelines for prevention and treatment, and current challenges. (23931206)
2013
2
Atopic Dermatitis, food allergy and dietary interventions. A tale of controversy. (24173200)
2013
3
The pH of water from various sources: an overview for recommendation for patients with atopic dermatitis. (23956962)
2013
4
Systemic contact dermatitis in a gold-allergic patient after treatment with an oral homeopathic drug. (23317995)
2013
5
IL-6 deficiency exacerbates skin inflammation in a murine model of irritant dermatitis. (22966985)
2013
6
Allergic contact dermatitis due to ginkgo tree fruit and leaf. (23965545)
2013
7
Rosmarinus officinalis L. as cause of contact dermatitis. (23827646)
2013
8
Apgar score is related to development of atopic dermatitis: cotwin control study. (24222775)
2013
9
Atopic dermatitis, and the role for a ceramide-dominant, physiologic lipid-based barrier repair emulsion. (24002150)
2013
10
Stress evaluation in adult patients with atopic dermatitis using salivary cortisol. (23971022)
2013
11
Allergic contact dermatitis due to sensitisation to sunscreen in two infants. (23287584)
2013
12
Formaldehyde in textiles--what dermatologists need to know about the relationship to contact dermatitis: a review of the US Government Accountability Office's Report to Congressional Committees. (22794805)
2012
13
Contact dermatitis to topical medicaments: a retrospective chart review from the Ottawa Hospital Patch Test Clinic. (23010827)
2012
14
Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice. (22594804)
2012
15
The association between filaggrin mutations, hand eczema and contact dermatitis: a clear picture is emerging. (23181836)
2012
16
Allergic contact dermatitis among construction workers detected in a clinic that did not specialize in occupational dermatitis. (22892770)
2012
17
Allergic contact dermatitis from cetyl alcohol. (21291645)
2011
18
A case of allergic contact dermatitis caused by glucan oligosaccharide. (19489973)
2009
19
Serum mucosa-associated epithelial chemokine in atopic dermatitis: a specific marker for severity. (20161852)
2009
20
Association factors for atopic dermatitis in nursery school children in Ishigaki islands - Kyushu University Ishigaki Atopic Dermatitis Study (KIDS). (18693163)
2008
21
A diagnostic pearl in allergic contact dermatitis to fragrances: the atomizer sign. (19090333)
2008
22
Sequence analysis of filaggrin gene by novel shotgun method in Japanese atopic dermatitis. (18420385)
2008
23
De novo occurrence of the filaggrin mutation p.R501X with prevalent mutation c.3321delA in a Japanese family with ichthyosis vulgaris complicated by atopic dermatitis. (18007582)
2008
24
Interferon-gamma secreted from peripheral blood mononuclear cells as a possible diagnostic marker for allergic contact dermatitis to gold. (16930235)
2006
25
Etiopathogenesis of atopic dermatitis--an overview. (15788148)
2005
26
JTP-27536 [(+)-1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-[(R)-3-cyclo-hexyl-1-phenylpropyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate], a novel inhibitor of immunoglobulins and interleukin-5 with anti-inflammatory properties in mouse allergic dermatitis model. (15821026)
2005
27
HTLV-I associated myelopathy/tropical spastic paraparesis in a 7-year-old boy associated with infective dermatitis. (15240193)
2004
28
Effectiveness of a hand care regimen with moisturizer in manufacturing facilities where workers are prone to occupational irritant dermatitis. (15573643)
2004
29
Topical application of FK506 (tacrolimus) ointment inhibits mite antigen-induced dermatitis by local action in NC/Nga mice. (14726632)
2004
30
Facial eruption of molluscum contagiosum during topical treatment of atopic dermatitis with tacrolimus. (15214914)
2004
31
Up-regulation of interleukin-13 receptor alpha1 on human keratinocytes in the skin of psoriasis and atopic dermatitis. (14527737)
2003
32
Differential susceptibility to staphylococcal superantigen (SsAg)-induced apoptosis of CD4+ T cells from atopic dermatitis patients and healthy subjects: the inhibitory effect of IL-4 on SsAg-induced apoptosis. (12847285)
2003
33
High interleukin-13 production by phytohaemagglutinin- and Der p 1-stimulated cord blood mononuclear cells is associated with the subsequent development of atopic dermatitis at the age of 3 years. (14616866)
2003
34
Evidence for increased expression of eotaxin and monocyte chemotactic protein-4 in atopic dermatitis. (10808183)
2000
35
Antibodies against tissue transglutaminase as a serological marker in dermatitis herpetiformis During]. (10907151)
2000
36
Diffuse erythema multiforme-like contact dermatitis caused by disperse blue 124 in a 2 year old child. (10343954)
1999
37
Neuropeptide modulation of Th1 and Th2 cytokines in peripheral blood mononuclear leucocytes in atopic dermatitis and non-atopic controls. (9470908)
1997
38
Coexistence of atopic dermatitis and lichen nitidus in three patients. (8829506)
1996
39
Complement profiles in human skin lymph during the course of irritant contact dermatitis. (7818276)
1994
40
Effect of hypoallergenic wheat (HAW-A1) on atopic dermatitis (AD) with wheat allergy, and its antigenic analysis using sera from patients with AD]. (8067902)
1994
41
Androgenetic alopecia--is contact dermatitis an accelerating factor? (2323197)
1990
42
Circumoral dermatitis and cheilitis caused by tartar control dentifrices. (2164535)
1990
43
Exfoliative dermatitis due to nifedipine. (2529896)
1989
44
Dyshidrotic eczema as an occupational dermatitis in metal workers. (2973394)
1988
45
Rifampin and exfoliative dermatitis. (2959187)
1987
46
Occupational dermatitis to 2,3-epoxypropyl trimethyl ammonium chloride. (2936558)
1986
47
Occupational dermatitis from cephalosporins. (2936563)
1986
48
Isoniazid-induced exfoliative dermatitis. (6459647)
1982
49
Quinidine-induced exfoliative dermatitis; with a brief review of quinidine idiosyncrasies. (14794501)
1951
50
Remarks on General Exfoliative Dermatitis. (20749264)
1879

Genetic Variations for Dermatitis

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Expression for genes affiliated with Dermatitis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dermatitis

Search GEO for disease gene expression data for Dermatitis.

Pathways for genes affiliated with Dermatitis

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Sources:
51QIAGEN, 29KEGG, 53Reactome, 37NCBI BioSystems Database
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Compounds for genes affiliated with Dermatitis

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Sources:
44Novoseek, 24HMDB, 49PharmGKB, 28IUPHAR, 11DrugBank, 59Tocris Bioscience
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Compounds related to Dermatitis according to GeneCards/GeneDecks:

(show top 50)    (show all 57)
idCompoundScoreTop Affiliating Genes
1allergens4411.9HRH1, IL5, CXCR3, IGHE, FLG, CCL27
2retinoic acid44 2412.9IGHE, FLG, CCR4, CCL11, IL5, ADH5
3tarc4411.8CCL11, CCR4, CCL27, IGHE, IL5, CXCR3
4rantes4411.8HRH1, CCR4, CCL11, CCL27, IL5, CXCR3
5dexamethasone44 49 28 1114.7CCL11, IL5, CXCR3, IGHE, CCL27, HRH1
6arginine4411.7IL5, CXCR3, DHX8, IGHE, FLG, ADH5
7histamine44 28 2413.6IL5, HRH1, IGHE, CCL11, CXCR3
8pge24411.5IL5, CCL11, CCL27, CXCR3, HRH1
9sodium cromoglycate4411.5IGHE, CCL11, IL5, HRH1
10cetirizine44 28 11 2414.5IL5, IGHE, CCL11, HRH1
11ketotifen44 1112.5IGHE, HRH1, IL5, CCL11
12ccl344 2812.5CCL11, CCR4, CXCR3, CCL27
13ccl444 2812.5CXCR3, CCL27, CCR4, CCL11
14prednisolone44 28 1113.5IGHE, IL5, CCR4, CCL11
15tacrolimus44 49 1113.4HRH1, IL5, CCL11, CXCR3
16mepyramine maleate5911.4DHX34, HRH1, DHX8
17histamine dihydrochloride5911.4DHX8, DHX34, HRH1
182-pyridylethylamine dihydrochloride5911.3DHX34, DHX8, HRH1
19clemastine fumarate5911.3HRH1, DHX34, DHX8
20unicap4411.3IGHE, IL5, CCL11
21oxatomide4411.3HRH1, IGHE, IL5
22anti-histamine4411.3IGHE, CCL11, HRH1
23astemizole44 59 28 1114.3DHX8, DHX34, HRH1
24nedocromil sodium4411.3IGHE, IL5, HRH1
25azelastine44 1112.3HRH1, IGHE, IL5
26indomethacin44 59 28 1114.3CCL11, IGHE, IL5, HRH1
27montelukast44 49 28 1114.3IL5, IGHE, CCL11
28budesonide44 49 1113.3IGHE, IL5, CCL11
29salbutamol44 49 28 11 2415.3IL5, CCL11, IGHE
30fluticasone propionate44 49 59 1114.3IGHE, CCL11, IL5
31pgd24411.3IGHE, CCL11, IL5
32infliximab44 49 1113.2IGHE, CXCR3, FLG
33methacholine44 1112.2CCL11, IGHE, IL5
34capsaicin44 2812.2IL5, IGHE, HRH1
35levocetirizine4411.1HRH1, CCL11
36omalizumab44 1112.1IL5, IGHE
37levocabastine44 28 1113.1HRH1, IL5
38beclomethasone dipropionate4411.0IGHE, IL5
39ovomucoid4411.0IL5, IGHE
40lte44411.0IL5, CCL11
41toluene diisocyanate4411.0IL5, IGHE
425-oxoete4411.0IL5, CCL11
43desloratadine44 1111.9HRH1, IGHE
44epinastine44 1111.9IL5, HRH1
45roxithromycin44 28 1112.9IL5, CCL11
46olopatadine44 1111.8HRH1, IGHE
47pranlukast44 28 1112.8CCL11, IL5
48loratadine44 11 2412.8HRH1, IGHE
49fexofenadine44 49 11 2413.7IL5, HRH1
50mcp 14410.5CXCR3, IL5

GO Terms for genes affiliated with Dermatitis

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16Gene Ontology
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Biological processes related to Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1inflammatory responseGO:00695411.1CCL11, CCR4, CXCR3, IL5, HRH1
2chemotaxisGO:00693511.1CXCR3, CCL27, CCR4, CCL11
3immune responseGO:00695510.9IL5, IGHE, CCL27, CCR4, CCL11
4eosinophil chemotaxisGO:04824510.8HRH1, CCL11

Molecular functions related to Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chemokine receptor activityGO:00495010.8CXCR3, CCR4

Products for genes affiliated with Dermatitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Dermatitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet