MCID: DRM007
MIFTS: 56

Dermatitis Herpetiformis malady

Categories: Genetic diseases, Rare diseases, Skin diseases, Immune diseases

Aliases & Classifications for Dermatitis Herpetiformis

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Sources:
10Disease Ontology, 45NIH Rare Diseases, 47Novoseek, 12DISEASES, 51Orphanet, 36MeSH, 65UMLS, 27ICD10, 29ICD9CM, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet, 61The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Dermatitis Herpetiformis:

Name: Dermatitis Herpetiformis 10 45 47 12 51 36 65
Duhring's Disease 10 45
Dermatitis Herpetiformis, Familial 65
Dermatosis Herpetiformis 10
 
Duhring Brocq Disease 45
Brocq-Duhring Disease 45
Durhing-Brocq Disease 51
Dh 45

Characteristics:

Orphanet epidemiological data:

51
dermatitis herpetiformis:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe),1-9/1000000 (Italy),1-9/100000 (Ireland),1-5/10000 (Ireland); Age of onset: All ages


Classifications:

Orphanet: 51 
Rare skin diseases


External Ids:

Disease Ontology10 DOID:8505
ICD1027 L13.0
ICD9CM29 694.0
MeSH36 D003874
NCIt42 C26742
Orphanet51 1656
ICD10 via Orphanet28 L13.0
MESH via Orphanet37 D003874
UMLS via Orphanet66 C0011608
UMLS65 C0011608, C1832586

Summaries for Dermatitis Herpetiformis

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NIH Rare Diseases:45 Dermatitis herpetiformis is a rare, chronic, skin disorder characterized by groups of severely itchy blisters and raised skin lesions. these are more common on the knees, elbows, buttocks and shoulder blades. the slow onset of symptoms usually begins during adulthood, but children can also be affected. other symptoms may include fluid-filled sores; red lesions that resemble hives; and itchiness, redness and burning. the exact cause of this disease is not known, but it is frequently associated with the inability to digest gluten. people with this disease are typically treated with the drug dapsone. last updated: 10/29/2014

MalaCards based summary: Dermatitis Herpetiformis, also known as duhring's disease, is related to subcorneal pustular dermatosis and purpura, and has symptoms including abnormal blistering of the skin, autoimmunity and recurrent fractures. An important gene associated with Dermatitis Herpetiformis is CD79A (CD79a Molecule), and among its related pathways are Primary immunodeficiency and A-beta Pathways: Uptake and Degradation. The drugs dapsone and sulfapyridine pwdr have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and bone, and related mouse phenotypes are renal/urinary system and homeostasis/metabolism.

Wikipedia:68 Dermatitis herpetiformis (DH), or Duhring\'s disease, is a chronic blistering skin condition,... more...

Related Diseases for Dermatitis Herpetiformis

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Diseases in the Dermatitis Herpetiformis family:

Juvenile Dermatitis Herpetiformis

Diseases related to Dermatitis Herpetiformis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 229)
idRelated DiseaseScoreTop Affiliating Genes
1subcorneal pustular dermatosis30.9CD79A, HLA-DQB1
2purpura30.9CD40LG, CD79A
3pemphigus30.8CD40LG, CD79A
4impetigo herpetiformis30.8CD79A, TGM2
5pityriasis rosea30.6CD40LG, CD79A
6membranous glomerulonephritis30.6CD40LG, CD79A
7systemic lupus erythematosus29.4CD40LG, CD79A, HLA-DQA1, HLA-DQB1
8rheumatoid arthritis29.4CD40LG, CD79A, HLA-DQA1, HLA-DQB1
9bullous pemphigoid27.4CD40LG, CD79A, FBN1, HLA-DQA1, HLA-DQB1, MMP12
10juvenile dermatitis herpetiformis12.4
11dehydrated hereditary stomatocytosis with or without pseudohyperkalemia and/or perinatal edema11.4
12dermatitis11.2
13typhus10.7CD40LG, CD79A
14pulmonary edema10.7CD40LG, CD79A
15congenital hypogammaglobulinemia10.7CD40LG, CD79A
16calabro syndrome10.7CD40LG, CD79A
17gamma heavy chain disease10.7CD40LG, CD79A
18exanthema subitum10.7CD40LG, CD79A
19osteomalacia10.7CD40LG, CD79A
20epidermolysis bullosa simplex10.7CD40LG, CD79A
21proliferative glomerulonephritis10.7CD40LG, CD79A
22cryopyrin-associated periodic syndrome10.7CD40LG, CD79A
23acute salpingitis10.7CD40LG, CD79A
24beriberi10.7CD40LG, CD79A
25cystitis10.7CD40LG, CD79A
26choroid plexus meningioma10.7CD40LG, CD79A
27immunotactoid glomerulopathy10.7CD40LG, CD79A
28ocular muscular dystrophy10.7CD79A, HLA-DQB1
29subacute delirium10.7CD40LG, CD79A
30alpha chain disease10.7CD40LG, CD79A
31dysgammaglobulinemia10.7CD40LG, CD79A
32generalized atherosclerosis10.7CD40LG, CD79A
33central sleep apnea10.7CD40LG, CD79A
34intellectual disability-obesity-prognathism-eye and skin anomalies syndrome10.7HLA-DQB1, MYO9B
35sialadenitis10.7CD40LG, CD79A
36ureteral lymphoma10.7CD40LG, CD79A
37mixed lacrimal gland cancer10.7CD40LG, CD79A
38somatoform disorder10.7CD40LG, CD79A
39aids phobia10.6CD40LG, CD79A
40ocular hypotension10.6CD40LG, CD79A
41differentiating neuroblastoma10.6CD40LG, CD79A
42tenosynovitis10.6CD40LG, CD79A
43brucella melitensis brucellosis10.6CD40LG, CD79A
44fallopian tube carcinoma10.6CD40LG, CD79A
45maxillary sinusitis10.6CD40LG, CD79A
46plasma protein metabolism disease10.6CD40LG, CD79A
47peripheral nervous system disease10.6CD40LG, CD79A
48primary systemic mycosis10.6CD40LG, CD79A
49impaired renal function disease10.6CD40LG, CD79A
50parasitic conjunctivitis10.6CD40LG, CD79A

Graphical network of the top 20 diseases related to Dermatitis Herpetiformis:



Diseases related to dermatitis herpetiformis

Symptoms for Dermatitis Herpetiformis

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Symptoms:

 51 (show all 15)
  • urticaria
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • macules
  • follicular/erythematous/edematous papules/milium
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment
  • negative nikolski's sign
  • pruritus/itching
  • malabsorption/chronic diarrhea/steatorrhea
  • mutiple fractures/bone fragility
  • autoimmunity/autoimmune reaction/autoantibodies
  • microcytic anemia
  • eczema
  • lichen
  • cutaneous edema
  • bone pain

HPO human phenotypes related to Dermatitis Herpetiformis:

(show all 13)
id Description Frequency HPO Source Accession
1 abnormal blistering of the skin hallmark (90%) HP:0008066
2 autoimmunity hallmark (90%) HP:0002960
3 recurrent fractures hallmark (90%) HP:0002757
4 malabsorption hallmark (90%) HP:0002024
5 microcytic anemia hallmark (90%) HP:0001935
6 hypermelanotic macule hallmark (90%) HP:0001034
7 urticaria hallmark (90%) HP:0001025
8 pruritus hallmark (90%) HP:0000989
9 eczema typical (50%) HP:0000964
10 lichenification occasional (7.5%) HP:0100725
11 bone pain occasional (7.5%) HP:0002653
12 edema occasional (7.5%) HP:0000969
13 pruritus HP:0000989

UMLS symptoms related to Dermatitis Herpetiformis:


coma blister

Drugs & Therapeutics for Dermatitis Herpetiformis

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Drugs for Dermatitis Herpetiformis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1AntibodiesPhase 1, Phase 24477
2ImmunoglobulinsPhase 1, Phase 24477
3
Dapsoneapproved, investigational6280-08-02955
Synonyms:
(4-sulfanilylphenyl)amine
1,1'-Sulfonylbis(4-aminobenzene)
1,1'-Sulfonylbis[4-aminobenzene]
1,1'-Sulphonylbis(4-aminobenzene)
1358F
32960_FLUKA
4,4' Diaminophenyl Sulfone
4,4'-Dapsone
4,4'-Diaminodiphenyl sulfone
4,4'-Diaminodiphenyl sulphone
4,4'-Diaminodiphenyl suphone
4,4'-Diaminodiphenylsulfone
4,4'-Sulfonylbisaniline
4,4'-Sulfonylbisbenzamine
4,4'-Sulfonylbisbenzenamine
4,4'-Sulfonylbisbenzeneamine
4,4'-Sulfonyldianilin
4,4'-Sulfonyldianiline
4,4'-Sulfonyldianiline (Dapsone)
4,4'-Sulphonylbisbenzamine
4,4'-Sulphonylbisbenzenamine
4,4'-Sulphonyldianiline
4,4'-diaminophenyl sulfone
4,4'-sulfonyldianiline
4,4-Diaminodifenylsulfon
4,4-Diaminodifenylsulfon [Czech]
4,4-Sulfonyldianiline
4-(4-Aminophenylsulfonyl)aniline
4-(4-Aminophenylsulfonyl)benzenamine
4-(4-amino-Benzenesulfonyl)-phenylamine
4-(4-aminophenyl)sulfonylaniline
4-Aminop henyl sulfone
4-Aminophenyl sulfone
4-Aminophenylsulfone
4-[(4-aminobenzene)sulfonyl]aniline
4-[(4-aminophenyl)sulfonyl]aniline
46158_FLUKA
46158_RIEDEL
80-08-0
A74807_ALDRICH
AB00051962
AB1004833
AC-10922
AC1L1EUH
AC1Q51WM
AC1Q51WN
AI3-08087
AKOS000119322
ALBB-005917
AZT + Dapsone cominbation
Acedapsone
Aczone
Aczone (TN)
Ambap80-08-0
Araldite HT
Araldite HT 976
Araldite Ht
Atrisone
Avlosulfon
Avlosulfone
Avlosulphone
Avsulfor
BIDD:GT0770
BPBio1_000143
BRD-K62363391-001-05-8
BRN 0788055
BSPBio_000129
BSPBio_002129
Bis(4-aminophenyl) sulfone
Bis(4-aminophenyl)sulfone
Bis(4-aminophenyl)sulphone
Bis(P-aminophenyl) sulfone
Bis(p-aminophenyl) sulfone
Bis(p-aminophenyl)sulphone
C07666
CAS-80-08-0
CBDivE_013582
CCRIS 192
CHEBI:4325
CHEMBL1043
CID2955
CPD000059064
Croysulfone
Croysulphone
D SS
D003622
D00592
D0089
DADPS
DAPSONE
DB00250
DDS
DDS (pharmaceutical)
DDS, diaphenylsulfone
DDS, pharmaceutical
DIAPHENYLSULFONE
DSS
DSS (VAN)
Dapsoderm-X
Dapson
Dapson-Fatol
Dapsona
Dapsona [INN-Spanish]
Dapsone
Dapsone (USP)
Dapsone [USAN:BAN]
Dapsonum
Dapsonum [INN-Latin]
Dds, Diaphenylsulfone
Dds, Pharmaceutical
Di(4-aminophenyl) sulfone
Di(4-aminophenyl)sulfone
Di(4-aminophenyl)sulphone
Di(p-aminophenyl) sulfone
Di(p-aminophenyl)sulphone
Diamino-4,4'-diphenyl sulfone
Diamino-4,4'-diphenyl sulphone
Diamino-diphenyl sulphone
Diaminodifenilsulfona
Diaminodifenilsulfona [Spanish]
Diaminodiphenyl Sulfone
Diaminodiphenyl sulfone
Diaminodiphenylsulfone
Diaphenylsulfon
 
Diaphenylsulfone
Diaphenylsulfone (JAN)
Diaphenylsulphon
Diaphenylsulphone
Dimitone
Diphenasone
Diphone
Disulone
DivK1c_000573
Dubronax
Dubronaz
Dumitone
EINECS 201-248-4
Eporal
F 1358
Fatol Brand of Dapsone
HMS1568G11
HMS1920C14
HMS2091K04
HMS501M15
HSDB 5073
HT 976
HY 976
Hardener HT 976
I01-3640
ICI
IDI1_000573
IN-201
KBio1_000573
KBio2_001368
KBio2_003936
KBio2_006504
KBio3_001349
KBioGR_000900
KBioSS_001368
LS-1790
MLS000069409
MLS001055349
MLS001076146
Metabolite C
Mex-America Brand of Dapsone
MolPort-001-780-172
N, N'-Diphenyl Sulfondiamide
N, N'-Diphenyl sulfondiamide
N,N'-Diphenyl sulfondiamide
NCGC00016322-01
NCGC00016322-02
NCGC00023946-03
NCGC00023946-04
NCGC00023946-05
NCGC00023946-06
NCI-C01718
NINDS_000573
NSC 6091
NSC 6091D
NSC-6091
NSC6091
Normet
Novophone
Oprea1_143052
Orsade Brand of Dapsone
P, P'-Sulfonyldianiline
P,P'-Diaminodiphenyl Sulfone
P,P'-diaminodiphenyl sulfone
P,P-Diaminodiphenyl Sulphone
P,P-Sulfonylbisbenzamine
P,P-Sulfonylbisbenzenamine
P,P-Sulphonylbisbenzamine
P,P-Sulphonylbisbenzenamine
P,P-Sulphonyldianiline
P-Aminophenyl Sulfone
P-Aminophenyl sulfone
Prestwick0_000035
Prestwick1_000035
Prestwick2_000035
Prestwick3_000035
Prestwick_152
Protogen
Recolip
SAM002554879
SMR000059064
SPBio_001025
SPBio_002050
SPECTRUM1500222
STK387118
Spectrum2_001133
Spectrum3_000375
Spectrum4_000310
Spectrum5_000825
Spectrum_000888
Sulfadione
Sulfanona-Mae
Sulfanona-mae
Sulfon-Mere
Sulfon-mere
Sulfona
Sulfona-MAE
Sulfona-Mae
Sulfone Ucb
Sulfone ucb
Sulfone, 4,4'-Diaminophenyl
Sulfonyldianiline
Sulphadione
Sulphon-Mere
Sulphon-mere
Sulphonyldianiline
Sumicure S
TL8005401
Tarimyl
UNII-8W5C518302
Udolac
W R 448
WLN: ZR DSWR DZ
WR 448
ZINC00006310
dapsone
p, p'-Sulfonyldianiline
p,p'-Diaminodiphenyl sulfone
p,p'-sulfonyldianiline
p,p-Diaminodiphenyl sulphone
p,p-Sulfonylbisbenzamine
p,p-Sulfonylbisbenzenamine
p,p-Sulphonylbisbenzamine
p,p-Sulphonylbisbenzenamine
p,p-Sulphonyldianiline
p-Aminophenyl sulfone
4
Folic Acidapproved, nutraceutical292459-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic Acid
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
 
Folsaeure
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
5Vitamin B Complex2847
6Folic Acid Antagonists1643
7Antiprotozoal Agents1730
8Anti-Bacterial Agents9140
9Antiparasitic Agents1854
10Anti-Infective Agents17220
11Antimalarials1058
12Vitamin B9Nutraceutical2924
13Folinic AcidNutraceutical2604
14FolateNutraceutical2924

Interventional clinical trials:

idNameStatusNCT IDPhase
1Study of Enzyme Supplements to Treat Celiac DiseaseActive, not recruitingNCT00962182Phase 1, Phase 2
2Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin DiseasesRecruitingNCT01952275
3Use of Dapsone Gel, 5% for Treating Dermatitis HerpetiformisNot yet recruitingNCT01115244

Search NIH Clinical Center for Dermatitis Herpetiformis

Inferred drug relations via UMLS65/NDF-RT43:


Cochrane evidence based reviews: dermatitis herpetiformis

Genetic Tests for Dermatitis Herpetiformis

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Anatomical Context for Dermatitis Herpetiformis

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MalaCards organs/tissues related to Dermatitis Herpetiformis:

33
Skin, T cells, Bone, Breast, Endothelial, Liver, Lung

Animal Models for Dermatitis Herpetiformis or affiliated genes

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MGI Mouse Phenotypes related to Dermatitis Herpetiformis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.5CD40LG, CD79A, FBN1, HLA-DQB1, TGM2
2MP:00053766.6CD40LG, CD79A, FBN1, HLA-DQB1, MMP12, MMP7
3MP:00053976.2CD40LG, CD79A, FBN1, HLA-DQA1, HLA-DQB1, MMP12
4MP:00053875.9CD40LG, CD79A, FBN1, HLA-DQA1, HLA-DQB1, MMP12

Publications for Dermatitis Herpetiformis

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Articles related to Dermatitis Herpetiformis:

(show top 50)    (show all 580)
idTitleAuthorsYear
1
Dermatitis Herpetiformis: Pathognomonic Transglutaminase IgA Deposits in the Skin and Excellent Prognosis on a Gluten-free Diet. (26059085)
2015
2
Evidence for a role of autoantibodies to heat shock protein 60, 70, and 90 in patients with dermatitis herpetiformis. (24643797)
2014
3
Transverse myelitis associated with an itchy rash and hyperckemia: neuromyelitis optica associated with dermatitis herpetiformis. (24637913)
2014
4
Dermatitis herpetiformis in Brazilan male celiac disease patients: A case series. (25544421)
2014
5
IL-17 expression in dermatitis herpetiformis and bullous pemphigoid. (23970818)
2013
6
Does dermatitis herpetiformis result in bone loss as coeliac disease does? A cross sectional study. (23859446)
2013
7
Management of dermatitis herpetiformis. (22560140)
2012
8
Long-term combination therapy of ustekinumab and dapsone in a patient with psoriasis and dermatitis herpetiformis Duhring. (22784106)
2012
9
Autoimmunity-driven enzymatic remodeling of the dermal-epidermal junction in bullous pemphigoid and dermatitis herpetiformis. (21916544)
2012
10
The long-term risk of malignancy following a diagnosis of coeliac disease or dermatitis herpetiformis: a cohort study. (22288441)
2012
11
Reduced mortality in dermatitis herpetiformis: a population-based study of 476 patients. (22708883)
2012
12
Discontinuing dapsone treatment and reintroducing dietary gluten in patients with dermatitis herpetiformis in remission: comment on "remission in dermatitis herpetiformis". (21422338)
2011
13
Inflammatory epidermolysis bullosa acquisita mimicking toxic epidermal necrolysis and dermatitis herpetiformis. (19663858)
2009
14
No increase in risk of fracture, malignancy or mortality in dermatitis herpetiformis: a cohort study. (18315580)
2008
15
Might dermatitis herpetiformis be associated with discoid lupus erythematosus? (18482033)
2008
16
Childhood dermatitis herpetiformis: a case report and review of the literature. (18246879)
2007
17
Permeability, zonulin production, and enteropathy in dermatitis herpetiformis. (15822038)
2005
18
A new model for dermatitis herpetiformis that uses HLA-DQ8 transgenic NOD mice. (15489956)
2004
19
Parallel expression of macrophage metalloelastase (MMP-12) in duodenal and skin lesions of patients with dermatitis herpetiformis. (11247893)
2001
20
Concordance of dermatitis herpetiformis and celiac disease in monozygous twins. (11121131)
2000
21
Dermatitis herpetiformis effectively treated with heparin, tetracycline and nicotinamide. (10844495)
2000
22
Tissue transglutaminase antibodies in dermatitis herpetiformis. (10490368)
1999
23
Hemidesmosomal molecular changes in dermatitis herpetiformis; decreased expression of BP230 and plectin/HD1 in uninvolved skin. (10416682)
1999
24
Th2-like cytokine activity in dermatitis herpetiformis. (9602868)
1998
25
Risk factors for ischaemic heart disease in patients with dermatitis herpetiformis. (9204017)
1997
26
Dermatitis herpetiformis following gastric surgery. (9006392)
1997
27
Dermatitis herpetiformis induced by nonsteroidal anti-inflammatory drugs. (8169023)
1994
28
IgA antibodies against reticulin and endomysium in the serum and gastrointestinal secretions of patients with dermatitis herpetiformis. (8049567)
1994
29
Efficacy of cyclosporine in two patients with dermatitis herpetiformis resistant to conventional therapy. (8496445)
1993
30
Increased jejunal intraepithelial lymphocytes bearing gamma/delta T-cell receptor in dermatitis herpetiformis. (1314748)
1992
31
Role of elemental diet in dermatitis herpetiformis. (1935210)
1991
32
Intestinal humoral immunity in dermatitis herpetiformis. (1975360)
1990
33
Laryngeal involvement in dermatitis herpetiformis. (2312825)
1990
34
Manic depression induced by dapsone in patient with dermatitis herpetiformis. (2510873)
1989
35
Normal IgA production by peripheral blood lymphocytes in dermatitis herpetiformis and linear IgA dermatosis. (2919896)
1989
36
Dermatitis herpetiformis. (3153433)
1988
37
Dermatitis herpetiformis: a case with palmar purpuric lesions treated with disodium cromoglycate. (3139724)
1988
38
Aggressive gluten challenge of dermatitis herpetiformis cases converts them from seronegative to seropositive for IgA-class endomysial antibodies. (3372760)
1988
39
Dermatitis herpetiformis and hemodialysis. (3678553)
1987
40
Dermatitis herpetiformis: relation between circulating immune complexes, small-intestinal mucosal status, and immunohistopathological findings. (3632036)
1987
41
IgA endomysium antibody in children with dermatitis herpetiformis treated with gluten-free diet. (3774647)
1986
42
Anti-endomysial antibodies. A serologic marker of dermatitis herpetiformis. (3513713)
1986
43
The relationship between dapsone dose, serum concentration and disease severity in dermatitis herpetiformis. (3954818)
1986
44
Characterization of circulating and cutaneous IgA immune complexes in patients with dermatitis herpetiformis. (4020133)
1985
45
Thyroid abnormalities in dermatitis herpetiformis. Prevalence of clinical thyroid disease and thyroid autoantibodies. (3966757)
1985
46
Intestinal permeability in patients with coeliac disease and dermatitis herpetiformis. (3934051)
1985
47
Atypical dermatitis herpetiformis in two patients with internal malignancy. (6744651)
1984
48
Adult coeliac disease. A case with ulceration, dermatitis herpetiformis and reticulosarcoma. (766153)
1976
49
Juvenile dermatitis herpetiformis (a case report). (4777767)
1973
50

Variations for Dermatitis Herpetiformis

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Expression for genes affiliated with Dermatitis Herpetiformis

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Search GEO for disease gene expression data for Dermatitis Herpetiformis.

Pathways for genes affiliated with Dermatitis Herpetiformis

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Pathways related to Dermatitis Herpetiformis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.8CD40LG, CD79A
29.6CD40LG, MMP12
3
Show member pathways
9.1CD40LG, HLA-DQA1, HLA-DQB1
49.1CD40LG, HLA-DQA1, HLA-DQB1

GO Terms for genes affiliated with Dermatitis Herpetiformis

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Cellular components related to Dermatitis Herpetiformis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:00426139.9HLA-DQA1, HLA-DQB1
2integral component of lumenal side of endoplasmic reticulum membraneGO:00715569.8HLA-DQA1, HLA-DQB1
3trans-Golgi network membraneGO:00325889.5HLA-DQA1, HLA-DQB1
4ER to Golgi transport vesicle membraneGO:00125079.2HLA-DQA1, HLA-DQB1

Biological processes related to Dermatitis Herpetiformis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1antigen processing and presentationGO:00198829.7HLA-DQA1, HLA-DQB1
2extracellular matrix disassemblyGO:00226178.7FBN1, MMP12, MMP7

Molecular functions related to Dermatitis Herpetiformis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein-glutamine gamma-glutamyltransferase activityGO:00038109.9TGM3, TGM6
2zinc ion bindingGO:00082709.0MMP12, MMP7, MYO9B

Sources for Dermatitis Herpetiformis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet