DM
MCID: DRM010
MIFTS: 71

Dermatomyositis (DM) malady

Rare diseases, Neuronal diseases, Nephrological diseases, Bone diseases, Skin diseases, Muscle diseases categories
Download this MalaCard

Summaries for Dermatomyositis

About this section


Fully expand this MalaCard
NIH Rare Diseases:42 Dermatomyositis is one of a group of acquired muscle diseases called inflammatory myopathies (disorder of muscle tissue or muscles), which are characterized by chronic muscle inflammation accompanied by muscle weakness. the cardinal symptom is a skin rash that precedes or accompanies progressive muscle weakness. dermatomyositis may occur at any age, but is most common in adults in their late 40s to early 60s, or children between 5 and 15 years of age. there is no cure for dermatomyositis, but the symptoms can be treated. options include medication, physical therapy, exercise, heat therapy (including microwave and ultrasound), orthotics and assistive devices, and rest. the cause of dermatomyositis is unknown. last updated: 8/26/2013

MalaCards based summary: Dermatomyositis, also known as polymyositis with skin involvement, is related to interstitial lung disease and inclusion body myositis, and has symptoms including anomalies of eyelids, eyelashes and lacrimal system, palpebral edema/periorbital edema and erythema/erythematous lesions/erythroderma/polymorphous erythema. An important gene associated with Dermatomyositis is IFIH1 (interferon induced with helicase C domain 1), and among its related pathways are Malaria and Thromboxane A2 receptor signaling. The drugs immunoglobulins, intravenous and potassium aminobenzoate and the compounds anticodon and tetramethylpyrazine have been mentioned in the context of this disorder. Affiliated tissues include muscle or, skin and lung.

Disease Ontology:8 A myositis that results in inflammation located in muscle or located in skin where a skin rash is often seen prior to the onset of muscle weakness. the disease may result from either a viral infection or an autoimmune reaction.

NINDS:43 Dermatomyositis is one of a group of muscle diseases known as the inflammatory myopathies, which are characterized by chronic muscle inflammation accompanied by muscle weakness.

Wikipedia:65 Dermatomyositis (DM) is a connective-tissue disease related to polymyositis (PM) that is characterized... more...

Aliases & Classifications for Dermatomyositis

About this section
Sources:
8Disease Ontology, 42NIH Rare Diseases, 43NINDS, 10DISEASES, 44Novoseek, 48Orphanet, 62UMLS, 39NCIt, 57SNOMED-CT, 27ICD9CM, 34MeSH, 35MESH via Orphanet, 26ICD10 via Orphanet, 63UMLS via Orphanet, 25ICD10
See all sources

Dermatomyositis, Aliases & Descriptions:

Name: Dermatomyositis 8 42 43 10 44 48
Polymyositis with Skin Involvement 8 62
Dermatopolymyositis 8 62
 
Dermatopolymyositis, Unspecified 8
Adult Type Dermatomyositis 62
Dm 48


Classifications:



Characteristics (Orphanet epidemiological data):

48
dermatomyositis:
Prevalence: 1-9/100000; Age of onset: Variable; Age of death: Any age


External Ids:

Disease Ontology8 DOID:10223
NCIt39 C26744
ICD9CM27 710.3
MESH via Orphanet35 D003882
ICD10 via Orphanet26 M33.0, M33.1
UMLS via Orphanet63 C0011633
ICD1025 M33, M33.9

Related Diseases for Dermatomyositis

About this section

Diseases in the Dermatomyositis family:

Adult Dermatomyositis

Diseases related to Dermatomyositis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 303)
idRelated DiseaseScoreTop Affiliating Genes
1interstitial lung disease31.3SFTPD, HARS
2inclusion body myositis31.1VCAM1, ICAM1
3myositis30.8HARS, VCAM1, CHKB, ICAM1, GARS
4myopathy30.8SDHB, CHKB, GARS
5polymyositis30.6HARS, SFTPD, VCAM1, CHKB, ICAM1, CCR7
6diabetes mellitus30.6IFIH1, ICAM1, VCAM1, HLA-DQA1
7systemic lupus erythematosus30.3CCR7, ICAM1, VCAM1, HLA-DQA1
8dermatitis30.3ICAM1, VCAM1, HARS
9melanoma30.2VCAM1, CHKB, ICAM1, CCR7, IFIH1
10oral lichen planus30.1ICAM1, VCAM1
11autoimmune thyroiditis29.9ICAM1, CHKB
12influenza29.9SFTPD, CCR7, IFIH1
13systemic scleroderma29.8ICAM1, VCAM1, SFTPD
14psoriasis29.8VCAM1, ICAM1, CCR7
15rheumatoid arthritis29.7SFTPD, VCAM1, CHKB, ICAM1, CCR7
16respiratory failure29.7ICAM1, SFTPD
17multiple sclerosis29.5HLA-DQA1, VCAM1, ICAM1, CCR7
18amyopathic dermatomyositis10.9
19adult dermatomyositis10.7
20calcinosis10.7
21pneumonia10.6
22lupus erythematosus10.6
23myotonic dystrophy10.5
24childhood type dermatomyositis10.5
25scleroderma10.5
26arthritis10.4
27panniculitis10.4
28breast cancer10.3
29adenocarcinoma10.3
30arteriosclerosis obliterans10.3ICAM1, VCAM1
31immunoglobulin a vasculitis10.3VCAM1, ICAM1
32skin disease10.3
33lipodystrophy10.3
34middle ear cholesteatoma10.2ICAM1, CHKB
35rheumatoid vasculitis10.2ICAM1, VCAM1
36leukostasis10.2ICAM1, VCAM1
37pneumatosis cystoides intestinalis10.2
38multicentric reticulohistiocytosis10.2
39connective tissue disease10.2
40fasciitis10.2
41vernal keratoconjunctivitis10.2ICAM1, VCAM1
42mitochondrial disorders10.2SDHB, CHKB
43cerebral malaria10.2ICAM1, VCAM1
44nasopharyngitis10.2
45germ cell cancer10.2
46vasculitis10.2
47diabetes insipidus10.2
48maturity-onset diabetes of the young10.2
49arteriosclerosis10.1VCAM1, ICAM1
50glomerulonephritis10.1

Graphical network of the top 20 diseases related to Dermatomyositis:



Diseases related to dermatomyositis

Symptoms for Dermatomyositis

About this section


Symptoms:

48 (show all 50)
  • anomalies of eyelids, eyelashes and lacrimal system
  • palpebral edema/periorbital edema
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • cutaneous edema
  • muscle weakness/flaccidity
  • myalgia/muscular pain
  • abnormal emg/electromyogram/electropmyography
  • autoimmunity/autoimmune reaction/autoantibodies
  • biological inflammatory syndrome/increased erythrocyte sedimentation rate/crp
  • dry/squaly skin/exfoliation
  • chronic skin infection/ulcerations/ulcers/cancrum
  • follicular/erythematous/edematous papules/milium
  • pruritus/itching
  • telangiectasic erythema/poikiloderma
  • hypotrichosis/atrichia/atrichiasis/scalp hairlessness
  • nails anomalies
  • lung fibrosis
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • cough
  • interstitial/restrictive pneumopathy/restrictive respiratory syndrome
  • repeat respiratory infections
  • acrocyanosis/raynaud's phenomenon/vasomotor disorders
  • hypotonia
  • articular/joint pain/arthralgia
  • arthritis/synovitis/synovial proliferation
  • periarticular tissue anomaly/extraarticular calcifications
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • asthenia/fatigue/weakness
  • skin hypoplasia/aplasia/atrophy
  • cellulitis/panniculitis/pseudocellulitis/inflammation of subcutaneous tissue
  • skin photosensitivity
  • telangiectasiae of the skin
  • feeding disorder/dysphagia/swallowing/sucking disorder/esophageal dyskinesia
  • pulmonary hypertension
  • abnormal cry/voice/phonation disorder/nasal speech
  • myocardium anomalies/myocarditis
  • pericardium anomalies/pericarditis/absence/cysts/pericardial effusion
  • cardiac rhythm disorder/arrhythmia
  • angor pectoris/myocardial infarction
  • vascularitis/vasculitides/arteritis
  • gangrena/necrosis
  • elocution disorders/dysarthria/dysphonia
  • eosinophils anomalies/hypereosinophilia
  • neoplasms/tumors
  • lung/bronchopulmonary neoplasm/tumor/carcinoma/cancer
  • breast neoplasm/tumor/carcinoma/cancer
  • ovary/fallopian tube neoplasm/tumor/carcinoma/cancer (excl. teratoma/germinoma)
  • gastrointestinal stromal tumor
  • lymphoma
  • fever/chilling

HPO human phenotypes related to Dermatomyositis:

(show all 43)
id Description Frequency HPO Source Accession
1 abnormality of the eye hallmark (90%) HP:0000478
2 muscle weakness hallmark (90%) HP:0001324
3 autoimmunity hallmark (90%) HP:0002960
4 myalgia hallmark (90%) HP:0003326
5 emg abnormality hallmark (90%) HP:0003457
6 periorbital edema hallmark (90%) HP:0100539
7 chondrocalcinosis typical (50%) HP:0000934
8 dry skin typical (50%) HP:0000958
9 pruritus typical (50%) HP:0000989
10 poikiloderma typical (50%) HP:0001029
11 acrocyanosis typical (50%) HP:0001063
12 muscular hypotonia typical (50%) HP:0001252
13 arthritis typical (50%) HP:0001369
14 abnormality of the nail typical (50%) HP:0001597
15 weight loss typical (50%) HP:0001824
16 restrictive lung disease typical (50%) HP:0002091
17 respiratory insufficiency typical (50%) HP:0002093
18 recurrent respiratory infections typical (50%) HP:0002205
19 pulmonary fibrosis typical (50%) HP:0002206
20 arthralgia typical (50%) HP:0002829
21 abnormal hair quantity typical (50%) HP:0011362
22 skin ulcer typical (50%) HP:0200042
23 cutaneous photosensitivity occasional (7.5%) HP:0000992
24 abnormality of the voice occasional (7.5%) HP:0001608
25 abnormality of the myocardium occasional (7.5%) HP:0001637
26 coronary artery disease occasional (7.5%) HP:0001677
27 abnormality of the pericardium occasional (7.5%) HP:0001697
28 abnormality of eosinophils occasional (7.5%) HP:0001879
29 pulmonary hypertension occasional (7.5%) HP:0002092
30 neurological speech impairment occasional (7.5%) HP:0002167
31 vasculitis occasional (7.5%) HP:0002633
32 lymphoma occasional (7.5%) HP:0002665
33 abnormality of temperature regulation occasional (7.5%) HP:0004370
34 aplasia/hypoplasia of the skin occasional (7.5%) HP:0008065
35 feeding difficulties in infancy occasional (7.5%) HP:0008872
36 arrhythmia occasional (7.5%) HP:0011675
37 neoplasm of the breast occasional (7.5%) HP:0100013
38 neoplasm of the lung occasional (7.5%) HP:0100526
39 teleangiectasia of the skin occasional (7.5%) HP:0100585
40 ovarian neoplasm occasional (7.5%) HP:0100615
41 cellulitis occasional (7.5%) HP:0100658
42 gastrointestinal stroma tumor occasional (7.5%) HP:0100723
43 gangrene occasional (7.5%) HP:0100758

Drugs & Therapeutics for Dermatomyositis

About this section

Drug clinical trials:

Search ClinicalTrials for Dermatomyositis

Search NIH Clinical Center for Dermatomyositis

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Dermatomyositis

About this section

Anatomical Context for Dermatomyositis

About this section

MalaCards organs/tissues related to Dermatomyositis:

32
Skin, Lung, Heart, Breast, T cells, Bone, Ovary, Testes, Thyroid, Monocytes, B cells, Endothelial, Tongue, Skeletal muscle, Colon, Prostate, Brain, Liver, Myeloid, Appendix

FMA organs/tissues related to Dermatomyositis:

14
Muscle or

Animal Models for Dermatomyositis or affiliated genes

About this section

Publications for Dermatomyositis

About this section

Articles related to Dermatomyositis:

(show top 50)    (show all 1048)
idTitleAuthorsYear
1
Increased subsequent risk of acute coronary syndrome for patients with dermatomyositis/polymyositis: a nationwide population-based retrospective cohort study. (25205256)
2014
2
Anti-CADM-140/MDA5 autoantibody titer correlates with disease activity and predicts disease outcome in patients with dermatomyositis and rapidly progressive interstitial lung disease. (22644102)
2013
3
Rituximab in the treatment of refractory adult and juvenile dermatomyositis and adult polymyositis: a randomized, placebo-phase trial. (23124935)
2013
4
Gemcitabine-induced radiation recall myositis in a patient with dermatomyositis. (24283707)
2013
5
Molecular profiling to diagnose a case of atypical dermatomyositis. (23732751)
2013
6
Low prevalence of anti-DFS70/LEDGF antibodies in patients with dermatomyositis and other systemic autoimmune rheumatic diseases. (23280167)
2013
7
Marked increase in serum KL-6 and surfactant proteinA D levels during the first 4A weeks after treatment predicts poor prognosis in patients with active interstitial pneumonia associated with polymyositis/dermatomyositis. (22983659)
2013
8
Mycophenolate mofetil therapy for rapidly progressive interstitial lung disease in a patient with clinically amyopathic dermatomyositis. (23615839)
2013
9
Age at onset and gender distribution of systemic lupus erythematosus, polymyositis/dermatomyositis, and systemic sclerosis in Japan. (22903259)
2013
10
Hydroxyurea-induced dermatomyositis: true amyopathic dermatomyositis or dermatomyositis-like eruption? (22515579)
2012
11
Design of the muscles in motion study: a randomized controlled trial to evaluate the efficacy and feasibility of an individually tailored home-based exercise training program for children and adolescents with juvenile dermatomyositis. (22721424)
2012
12
Anti-TIF1I^ antibodies (anti-p155) in adult patients with dermatomyositis: comparison of different diagnostic assays. (22294626)
2012
13
Pneumomediastinum and massive subcutaneous emphysema associated with dermatomyositis. (23257541)
2012
14
Predictors of survival in a cohort of patients with polymyositis and dermatomyositis: effect of corticosteroids, methotrexate and azathioprine. (22284862)
2012
15
Is dermatomyositis in patients with rheumatoid arthritis induced by anti-TNF-I+ therapy? (21221687)
2011
16
Oral manifestations as important symptoms for juvenile dermatomyositis early diagnosis: a case report. (20659183)
2011
17
Cytomegalovirus-associated gastric ulcers in a patient with dermatomyositis treated with steroid and cyclophosphamide pulse therapy. (21915824)
2011
18
Comparison of clinical features and drug therapies among European and Latin American patients with juvenile dermatomyositis. (21345298)
2011
19
The RIG-I-like receptor IFIH1/MDA5 is a dermatomyositis-specific autoantigen identified by the anti-CADM-140 antibody. (20015976)
2010
20
Reversed halo sign associated with dermatomyositis. (20686316)
2010
21
Juvenile-onset clinically amyopathic dermatomyositis: an overview of recent progress in diagnosis and management. (20034339)
2010
22
Destructive arthropathy associated with dermatomyositis sine myositis positive for anti-Jo-1 and anti-cyclic citrullinated peptide antibodies. (19738232)
2009
23
Vascular endothelial growth factor is highly expressed in muscle tissue of patients with polymyositis and patients with dermatomyositis. (18821695)
2008
24
Fine-needle aspiration biopsy cytology of cutaneous calcinosis in a 74-year-old woman with dermatomyositis on methotrexate therapy: a case report. (18702364)
2008
25
Disease-specific quality indicators, outcome measures and guidelines in polymyositis and dermatomyositis. (18021522)
2007
26
Plasmacytoid dendritic cells in inflamed muscle of patients with juvenile dermatomyositis. (17469160)
2007
27
Lipodystrophy and metabolic abnormalities in a case of adult dermatomyositis. (17938031)
2007
28
Dermatomyositis, lobar panniculitis and inflammatory myopathy with abundant macrophages. (16809038)
2006
29
Genetically determined imbalance between serum levels of tumour necrosis factor (TNF) and interleukin (IL)-10 is associated with anti-Jo-1 and anti-Ro52 autoantibodies in patients with poly- and dermatomyositis. (16895750)
2006
30
Increased Fas and Bcl-2 expression on peripheral blood T and B lymphocytes from juvenile-onset systemic lupus erythematosus, but not from juvenile rheumatoid arthritis and juvenile dermatomyositis. (17162369)
2006
31
Identification of autoantibodies elicited in a patient with prostate cancer presenting as dermatomyositis. (16643611)
2006
32
Use of etanercept in the treatment of dermatomyositis: a case series. (16960940)
2006
33
Diagnostic significance of membrane attack complex and vitronectin in childhood dermatomyositis. (16159528)
2005
34
Intravenous cyclophosphamide pulse therapy in juvenile dermatomyositis. A review of efficacy and safety. (14722349)
2004
35
Update on juvenile dermatomyositis: new advances in understanding its etiopathogenesis. (12960487)
2003
36
Juvenile dermatomyositis associated with lipodystrophy. (17642934)
2003
37
Parathyroid hormone-related protein production by adenocarcinoma in Barrett's esophagus patient with dermatomyositis. (11478513)
2001
38
Amyopathic dermatomyositis in children: a diagnostic and therapeutic dilemma. (17039128)
2001
39
Aerobic capacity in adult dermatomyositis/polymyositis patients and healthy controls. (10638867)
2000
40
Elevation of serum soluble tumour necrosis factor receptors in patients with polymyositis and dermatomyositis. (11055823)
2000
41
Dystrophic calcification in adult dermatomyositis: neuroimage. (11146618)
2000
42
Pneumatosis cystoides intestinalis in a patient with dermatomyositis. (10615280)
1999
43
Benefit of 6 months long-term physical training in polymyositis/dermatomyositis patients. (9973161)
1998
44
Germ cell cancer and dermatomyositis. (9543617)
1998
45
Low-dose methotrexate as an adjunctive therapy with surgery for ectropion complicating dermatomyositis. (8829501)
1996
46
Amyopathic dermatomyositis. (7492141)
1995
47
Relationship of cancer to inflammatory muscle diseases. Dermatomyositis, polymyositis, and inclusion body myositis. (7855330)
1994
48
Severe secondary amyloidosis in a dog with dermatomyositis. (2474585)
1989
49
Early ultrastructural alterations in adult dermatomyositis. Capillary abnormalities precede other structural changes in muscle. (2614466)
1989
50
Membranous glomerulonephritis, dermatomyositis, and bronchial carcinoma. (227526)
1979

Variations for Dermatomyositis

About this section

Expression for genes affiliated with Dermatomyositis

About this section
Expression patterns in normal tissues for genes affiliated with Dermatomyositis

Search GEO for disease gene expression data for Dermatomyositis.

Pathways for genes affiliated with Dermatomyositis

About this section

Compounds for genes affiliated with Dermatomyositis

About this section

Compounds related to Dermatomyositis according to GeneCards/GeneDecks:

(show top 50)    (show all 65)
idCompoundScoreTop Affiliating Genes
1anticodon4410.2KARS, GARS
2tetramethylpyrazine4410.1ICAM1, CHKB
3sodium cromoglycate4410.1ICAM1, VCAM1
4loratadine44 24 1112.1ICAM1, VCAM1
58 methoxypsoralen4410.1ICAM1, VCAM1
6aminoacyl-trna4410.0KARS, IARS, GARS
7sele4410.0VCAM1, ICAM1
8trna4410.0GARS, IARS, KARS
9helenalin4410.0ICAM1, VCAM1
10hcec4410.0VCAM1, ICAM1
11gliclazide44 50 1112.0VCAM1, ICAM1
12cuprophan4410.0ICAM1, VCAM1
13slex449.9VCAM1, ICAM1
14mycophenolic acid44 50 1111.9ICAM1, VCAM1
15apocynin44 6110.9ICAM1, VCAM1
16hydroxylysine449.9CHKB, SFTPD
17polymyxin b449.9VCAM1, ICAM1
18fluvastatin44 50 28 1112.8ICAM1, CHKB, VCAM1
19Adenosine monophosphate24 1110.8HARS, KARS, IARS, GARS
20phosphoric acid44 2410.8HARS, KARS, IARS, GARS
21pyrophosphate44 2410.8HARS, KARS, IARS, GARS
22pravastatin44 50 28 24 1113.8VCAM1, CHKB, ICAM1
23atorvastatin44 50 28 24 1113.7VCAM1, CHKB, ICAM1
24thenoyltrifluoroacetone44 1110.7SDHB, VCAM1
25okt3449.7ICAM1, VCAM1
26simvastatin44 50 61 28 24 1114.7VCAM1, CHKB, ICAM1
27beta-hydroxybutyrate449.7SDHB, CHKB
28groalpha449.6ICAM1, VCAM1
29triptolide449.5CCR7, ICAM1
30prednisolone44 28 1111.5SFTPD, VCAM1, CHKB
31budesonide44 50 1111.5ICAM1, VCAM1, SFTPD
32gssg449.5SDHB, CHKB
33Adenosine triphosphate24 1110.4HARS, KARS, CHKB, IARS, GARS
34rantes449.4VCAM1, ICAM1, CCR7
35leucine449.3SFTPD, KARS, CHKB, GARS
36matrigel449.2VCAM1, ICAM1, CCR7
37pge2449.2CCR7, ICAM1, CHKB, VCAM1
38endotoxin449.2SFTPD, VCAM1, CHKB, ICAM1
39polysaccharide449.1SFTPD, VCAM1, CHKB, ICAM1
40mannitol44 1110.0ICAM1, CHKB, VCAM1, SDHB
41norepinephrine44 24 1110.8SDHB, VCAM1, CHKB, CCR7
42aspartate448.8HLA-DQA1, SDHB, VCAM1, CHKB
43cholesterol44 28 24 1111.6CHKB, VCAM1, SDHB, SFTPD
44arginine448.6HLA-DQA1, KARS, SDHB, VCAM1, CHKB
45dexamethasone44 50 28 1111.4SFTPD, VCAM1, CHKB, ICAM1
46lactate448.3SFTPD, SDHB, VCAM1, CHKB, ICAM1
47alanine448.3KARS, SDHB, VCAM1, CHKB, CCR7, GARS
48oxygen44 249.3SFTPD, SDHB, VCAM1, CHKB, ICAM1
49cysteine448.2SFTPD, KARS, SDHB, VCAM1, CHKB, GARS
50calcium44 50 24 1110.7GARS, CCR7, CHKB, SDHB, KARS, SFTPD

GO Terms for genes affiliated with Dermatomyositis

About this section

Cellular components related to Dermatomyositis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098978.9CCR7, ICAM1, VCAM1
2cytosolGO:0058298.7GARS, IFIH1, IARS, CHKB, KARS, HARS

Biological processes related to Dermatomyositis according to GeneCards/GeneDecks:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1diadenosine tetraphosphate biosynthetic processGO:01596610.1GARS, KARS
2membrane to membrane dockingGO:0226149.9VCAM1, ICAM1
3leukocyte cell-cell adhesionGO:0071599.8ICAM1, VCAM1
4heterophilic cell-cell adhesionGO:0071579.8VCAM1, ICAM1
5response to ionizing radiationGO:0102129.7ICAM1, VCAM1
6cellular response to glucose stimulusGO:0713339.6ICAM1, VCAM1
7tRNA aminoacylation for protein translationGO:0064189.6GARS, IARS, KARS, HARS
8interferon-gamma-mediated signaling pathwayGO:0603339.4HLA-DQA1, VCAM1, ICAM1
9gene expressionGO:0104679.3HARS, KARS, IARS, GARS
10cytokine-mediated signaling pathwayGO:0192219.3ICAM1, VCAM1, HLA-DQA1
11positive regulation of actin filament polymerizationGO:0308389.2CCR7, ICAM1

Molecular functions related to Dermatomyositis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1helicase activityGO:00438610.0IFIH1, CHD3
2ATP bindingGO:0055248.2GARS, IFIH1, IARS, CHD3, CHKB, KARS

Products for genes affiliated with Dermatomyositis

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Dermatomyositis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet