MCID: DRM011
MIFTS: 43

Dermatophytosis malady

Infectious diseases category

Summaries for Dermatophytosis

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A cutaneous mycosis that results in fungal infection located in scalp, located in glabrous skin, or located in nail, has material basis in ascomycota fungi that belong to a group called dermatophytes, which have the ability to utilize keratin as a nutrient source.

MalaCards: Dermatophytosis is related to candidiasis and tinea unguium. An important gene associated with Dermatophytosis is LTF (lactotransferrin), and among its related pathways are Cytokines and Inflammatory Response and IL12 signaling mediated by STAT4. The compounds leupeptin and polymyxin b have been mentioned in the context of this disorder. Affiliated tissues include nail, glabrous skin and scalp.

Wikipedia:63 Dermatophytosis is a clinical condition caused by fungal infection of the skin in humans, pets such as... more...

Aliases & Classifications for Dermatophytosis

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 39NCIt, 34MeSH, 56SNOMED-CT, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

dermatophytosis 8 10 60


External Ids:

Disease Ontology8 DOID:8913
NCIt39 C26745
MeSH34 D003881
ICD9CM27 110, 110.9
ICD1025 B35, B35.9

Related Diseases for Dermatophytosis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Dermatophytosis:



Diseases related to dermatophytosis

Clinical Features for Dermatophytosis

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Drugs & Therapeutics for Dermatophytosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Dermatophytosis

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Anatomical Context for Dermatophytosis

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Sources:
32MalaCards, 14FMA
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MalaCards organs/tissues related to Dermatophytosis:

32
Skin, Testes, T cells, Thymus, Monocytes, Liver, Lymph node

FMA organs/tissues related to Dermatophytosis:

14
Nail, Glabrous skin, Scalp

Animal Models for Dermatophytosis or affiliated genes

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Publications for Dermatophytosis

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50PubMed
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Articles related to Dermatophytosis:

(show top 50)    (show all 495)
idTitleAuthorsYear
1
Changes in serum chemistry values in shelter cats treated with 21 consecutive days of oral itraconazole for dermatophytosis. (23889285)
2013
2
A herbal antifungal formulation of Thymus serpillum, Origanum vulgare and Rosmarinus officinalis for treating ovine dermatophytosis due to Trichophyton mentagrophytes. (23368893)
2013
3
Efficacy of topical antifungal agents in the treatment of dermatophytosis: an incomplete meta-analysis. (24132320)
2013
4
Deep dermatophytosis and inherited CARD9 deficiency. (24131138)
2013
5
Dermatophytosis and papular eosinophilic/mastocytic dermatitis (urticaria pigmentosa-like dermatitis) in three Devon Rex cats. (22736683)
2012
6
Canine dermatophytosis caused by Trichophyton rubrum: an example of man-to-dog transmission. (21771108)
2012
7
Dermatophytosis and SjAPgren-Larsson syndrome: foe or friend? (21834825)
2011
8
Disruption of barrier function in dermatophytosis and pityriasis versicolor. (21950511)
2011
9
Dermatophytosis (Trichophyton mentagrophytes) in a Coquerel's sifaka (Propithecus coquereli). (22204079)
2011
10
Efficacy of terbinafine compared to lanoconazole and luliconazole in the topical treatment of dermatophytosis in a guinea pig model. (20370362)
2010
11
Dermatophytosis in Western Africa: a review. (21717868)
2010
12
Wolf's isotopic response: large annular polycyclic lichen planus occurring on healed lesions of dermatophytosis. (18624876)
2009
13
Treatment of dermatophytosis in young cattle with propolis and Whitfield's ointment. (19596679)
2009
14
Molecular approaches in the diagnosis of dermatophytosis. (18481195)
2008
15
Immunoprophylaxis of dermatophytosis in animals. (18478355)
2008
16
In vivo efficacy and pharmacokinetics of voriconazole in an animal model of dermatophytosis. (17576826)
2007
17
Markers for host-induced gene expression in Trichophyton dermatophytosis. (16177334)
2005
18
Dermatophyte growth and degradation of human stratum corneum in vitro (pathogenesis of dermatophytosis). (16599028)
2005
19
Interdigital tinea pedis (dermatophytosis simplex and complex) and treatment with ciclopirox 0.77% gel. (12895184)
2003
20
Dermatophytosis consensus meeting: Introduction. (11044284)
2000
21
Miconazole/chlorhexidine shampoo as an adjunct to systemic therapy in controlling dermatophytosis in cats. (10340245)
1999
22
Dermatophytosis: association between ABO blood groups and reactivity to the trichophytin. (10602542)
1999
23
Chronic dermatophytosis caused by Trichophyton rubrum. (8784306)
1996
24
Dermatophytosis in northern Greece during the decade 1981-1990. (7477093)
1995
25
Immunoprophylaxis of bovine dermatophytosis. (7773918)
1995
26
Decreased release of interferon-gamma by peripheral blood mononuclear cells of patients with chronic dermatophytosis in response to stimulation with trichophytin. (7747546)
1995
27
Dermatophytosis in a Steller sea lion (Eumetopias jubatus). (7948389)
1994
28
Chronic dermatophytosis: what is special about Trichophyton rubrum? (8060745)
1994
29
Treatment of dermatophytosis with new systemic antifungal agent, itraconazole. (1322949)
1992
30
Advances in dermatophytes and dermatophytosis. (1474455)
1992
31
Dermatophytosis of children in Kuwait. (1574472)
1992
32
Case for diagnosis. Panniculitis, pyogranulomatous, diffuse, severe, with numerous fungal aggregates; etiology--consistent with deep dermatophytosis. (2125345)
1990
33
Dermatophyte fungi in the Guinea Savannah region of Nigeria and the changing phase of dermatophytosis in Nigeria. (2677715)
1989
34
Hereditary palmoplantar keratoderma and dermatophytosis. (2968959)
1988
35
New oral treatments for dermatophytosis. (2850758)
1988
36
Sulconazole versus clotrimazole in the treatment of dermatophytosis. (3311492)
1986
37
Nosocomial dermatophytosis caused by Microsporum canis in a newborn department. (3641789)
1986
38
Antifungal therapy of dermatophytosis in guinea pigs and congenitally athymic rats. (4039795)
1985
39
Cell-mediated immunity in experimental murine dermatophytosis. II. Adoptive transfer of immunity to dermatophyte infection by lymphoid cells from donors with acute or chronic infections. (6333384)
1984
40
Dermatophytosis due to Microsporum gypseum in a pet rabbit - a case report. (7110195)
1982
41
Immunology of dermatophytosis: lack of immunity and hyperimmunity. (7128195)
1982
42
Serum IgE level and T-cell count in chronic dermatophytosis. (6972004)
1981
43
Erythema multiforme in dermatophytosis. (6775223)
1980
44
Dermatophytosis and mycotic keratitis. (7216348)
1980
45
Trichophyton mentagrophytes dermatophytosis in wild fox. (7463597)
1980
46
Studies on dermatophytosis in dogs. III. An experimental study on some factors for establishment of infection with Microsporum gypseum of soil origin. (642221)
1978
47
Chronic mucocutaneous candidiasis, dermatophytosis and defective cellular immunity in monozygotic twins. (4134659)
1974
48
Significance of serum fungal inhibitory factor in dermatophytosis. (4210549)
1974
49
Study of microbial ecology of Thai women with dermatophytosis. (4583789)
1973
50
Griseofulvin-containing medium for simplified diagnosis of dermatophytosis. (11851259)
1965

Genetic Variations for Dermatophytosis

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Expression for genes affiliated with Dermatophytosis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dermatophytosis

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Pathways for genes affiliated with Dermatophytosis

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Sources:
37NCBI BioSystems Database
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Pathways related to Dermatophytosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8CD4, IFNG
29.8CD4, IFNG
39.5LPHN2, LPHN1

Compounds for genes affiliated with Dermatophytosis

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44Novoseek, 49PharmGKB, 11DrugBank
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Compounds related to Dermatophytosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1leupeptin449.9LTF, CD4
2polymyxin b449.7IFNG, LTF
3neopterin449.6CD4, LTF, IFNG
4budesonide44 49 1111.5LTF, IFNG
5alpha-latrotoxin449.5LPHN2, LPHN1

GO Terms for genes affiliated with Dermatophytosis

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16Gene Ontology
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Biological processes related to Dermatophytosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1humoral immune responseGO:0069599.8LTF, IFNG

Molecular functions related to Dermatophytosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1latrotoxin receptor activityGO:0165249.5LPHN2, LPHN1

Products for genes affiliated with Dermatophytosis

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Sources for Dermatophytosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet