MCID: DRM003
MIFTS: 26

Dermatosis Papulosa Nigra malady

Skin diseases category

Aliases & Classifications for Dermatosis Papulosa Nigra

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Dermatosis Papulosa Nigra, Aliases & Descriptions:

Name: Dermatosis Papulosa Nigra 9 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


External Ids:

Disease Ontology9 DOID:4400
NCIt38 C2984

Summaries for Dermatosis Papulosa Nigra

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Wikipedia:63 Dermatosis papulosa nigra (DPN) is a condition of many small, benign skin lesions on the face, a... more...

MalaCards based summary: Dermatosis Papulosa Nigra is related to keratosis and blindness, and has symptoms including abnormality of the skin An important gene associated with Dermatosis Papulosa Nigra is FGFR3 (fibroblast growth factor receptor 3), and among its related pathways are Ras signaling pathway and MicroRNAs in cancer. The compounds imatinib and phosphotyrosine have been mentioned in the context of this disorder. Affiliated tissues include skin, and related mouse phenotype tumorigenesis.

Related Diseases for Dermatosis Papulosa Nigra

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Graphical network of diseases related to Dermatosis Papulosa Nigra:



Diseases related to dermatosis papulosa nigra

Symptoms for Dermatosis Papulosa Nigra

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HPO human phenotypes related to Dermatosis Papulosa Nigra:

id Description Frequency HPO Source Accession
1 abnormality of the skin HP:0000951

Drugs & Therapeutics for Dermatosis Papulosa Nigra

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Drug clinical trials:

Search ClinicalTrials for Dermatosis Papulosa Nigra

Search NIH Clinical Center for Dermatosis Papulosa Nigra

Genetic Tests for Dermatosis Papulosa Nigra

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Anatomical Context for Dermatosis Papulosa Nigra

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MalaCards organs/tissues related to Dermatosis Papulosa Nigra:

31
Skin

Animal Models for Dermatosis Papulosa Nigra or affiliated genes

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MGI Mouse Phenotypes related to Dermatosis Papulosa Nigra:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.1FGFR3, PIK3CA

Publications for Dermatosis Papulosa Nigra

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Articles related to Dermatosis Papulosa Nigra:

(show all 18)
idTitleAuthorsYear
1
Dermatosis Papulosa Nigra and 10,600-nm CO2 laser, a good choice. (24131098)
2013
2
Postprocedural wound-healing efficacy following removal of dermatosis papulosa nigra lesions in an African American population: a comparison of a skin protectant ointment and a topical antibiotic. (21247663)
2011
3
Clinical features and treatment of dermatosis papulosa nigra in migrants to Italy. (21137605)
2010
4
FGFR3 and PIK3CA mutations in stucco keratosis and dermatosis papulosa nigra. (19845664)
2010
5
Treatment of dermatosis papulosa nigra in 10 patients: a comparison trial of electrodesiccation, pulsed dye laser, and curettage. (21040130)
2010
6
Comparison of electrodesiccation and potassium-titanyl-phosphate laser for treatment of dermatosis papulosa nigra. (19469798)
2009
7
Dermatosis papulosa nigra treatment with fractional photothermolysis. (19796255)
2009
8
Treatment of dermatosis papulosa nigra with a 1064 nm Nd:YAG laser: report of two cases. (18569266)
2008
9
Dermatosis papulosa nigra in Dakar, Senegal. (17919208)
2007
10
Eruptive dermatosis papulosa nigra as a possible sign of internal malignancy. (17269973)
2007
11
A randomized, double-blind comparison of two topical anesthetic formulations prior to electrodesiccation of dermatosis papulosa nigra. (16393591)
2006
12
Dermatosis papulosa nigra in a young child. (8302739)
1993
13
A surgical approach for dermatosis papulosa nigra. (6229500)
1983
14
Dermatosis papulosa nigra. (6226495)
1983
15
Dermatosis papulosa nigra and seborrheic keratoses: clinical aspects. (7386792)
1980
16
Dermatosis papulosa nigra. (5662294)
1968
17
DERMATOSIS PAPULOSA NIGRA. (14122095)
1964
18
A case for diagnosis [dermatosis papulosa nigra?]. (18101154)
1948

Variations for Dermatosis Papulosa Nigra

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Expression for genes affiliated with Dermatosis Papulosa Nigra

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Search GEO for disease gene expression data for Dermatosis Papulosa Nigra.

Pathways for genes affiliated with Dermatosis Papulosa Nigra

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Pathways related to Dermatosis Papulosa Nigra according to GeneCards Suite gene sharing:

(show all 15)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1FGFR3, PIK3CA
29.1FGFR3, PIK3CA
39.1PIK3CA, FGFR3
49.1FGFR3, PIK3CA
5
Show member pathways
9.1FGFR3, PIK3CA
6
Show member pathways
9.1FGFR3, PIK3CA
7
Show member pathways
9.1FGFR3, PIK3CA
8
Show member pathways
9.1PIK3CA, FGFR3
9
Show member pathways
9.1FGFR3, PIK3CA
10
Show member pathways
9.1FGFR3, PIK3CA
11
Show member pathways
9.1PIK3CA, FGFR3
12
Show member pathways
9.1FGFR3, PIK3CA
13
Show member pathways
9.1FGFR3, PIK3CA
14
Show member pathways
Signaling Pathways in Glioblastoma36
9.1FGFR3, PIK3CA
15
Show member pathways
9.1FGFR3, PIK3CA

Compounds for genes affiliated with Dermatosis Papulosa Nigra

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Sources:
43Novoseek, 49PharmGKB, 12DrugBank, 28IUPHAR, 24HMDB
See all sources

Compounds related to Dermatosis Papulosa Nigra according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1imatinib43 49 1211.4FGFR3, PIK3CA
2phosphotyrosine439.3FGFR3, PIK3CA
3doxorubicin43 49 1211.3PIK3CA, FGFR3
4dexamethasone43 49 28 1212.3FGFR3, PIK3CA
5vegf439.2FGFR3, PIK3CA
6arginine439.2PIK3CA, FGFR3
7threonine439.1FGFR3, PIK3CA
8Adenosine triphosphate24 1210.1FGFR3, PIK3CA
9glutamate439.0FGFR3, PIK3CA
10adp43 28 2410.8FGFR3, PIK3CA

GO Terms for genes affiliated with Dermatosis Papulosa Nigra

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Biological processes related to Dermatosis Papulosa Nigra according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1phosphatidylinositol-mediated signalingGO:00480159.3FGFR3, PIK3CA
2insulin receptor signaling pathwayGO:00082869.2FGFR3, PIK3CA
3fibroblast growth factor receptor signaling pathwayGO:00085439.2FGFR3, PIK3CA
4Fc-epsilon receptor signaling pathwayGO:00380959.1PIK3CA, FGFR3
5innate immune responseGO:00450879.1FGFR3, PIK3CA
6epidermal growth factor receptor signaling pathwayGO:00071739.0FGFR3, PIK3CA
7neurotrophin TRK receptor signaling pathwayGO:00480118.8FGFR3, PIK3CA

Products for genes affiliated with Dermatosis Papulosa Nigra

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Dermatosis Papulosa Nigra

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet