DIG
MCID: DSM006
MIFTS: 16

Desmoplastic Infantile Ganglioglioma (DIG) malady

Summaries for Desmoplastic Infantile Ganglioglioma

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42NIH Rare Diseases, 32MalaCards
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NIH Rare Diseases:42 Desmoplastic infantile gangliomas (digs) are rare brain tumors that are normally located in the frontal or parietal lobes of the brain. they are usually diagnosed before 18 months of age with most infants presenting with a short duration of symptoms. although seizures are not commonly observed, a bulging fontanelle, rapid head growth, vomiting, and a sunset sign are usually noted. the standard treatment for digs is surgical resection (surgical procedure in which the portion of the brain with the tumor is removed). last updated: 7/30/2013

MalaCards: Desmoplastic Infantile Ganglioglioma, also known as DIG, is related to ganglioglioma and astrocytoma. An important gene associated with Desmoplastic Infantile Ganglioglioma is MYCN (v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog). The compounds valproic acid and agar have been mentioned in the context of this disorder. Affiliated tissues include brain and parietal lobe.

Aliases & Classifications for Desmoplastic Infantile Ganglioglioma

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42NIH Rare Diseases, 60UMLS
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Aliases & Descriptions:

desmoplastic infantile ganglioglioma 42 60
dig 42


Related Diseases for Desmoplastic Infantile Ganglioglioma

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17GeneCards, 18GeneDecks
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Diseases related to Desmoplastic Infantile Ganglioglioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 20)
idRelated DiseaseScoreTop Affiliating Genes
1ganglioglioma11.1
2astrocytoma10.4
3cerebritis10.3
4pleomorphic xanthoastrocytoma10.3
5desmoplastic infantile astrocytoma/ganglioglioma10.3
6factor v leiden thrombophilia10.0CP, MYCN
7burkitt's lymphoma10.0CP, MYCN
8brain cancer10.0CP, MYCN
9non-hodgkin lymphoma10.0CP, MYCN
10celiac disease9.9
11alzheimer's disease9.9
12blastomycosis9.9
13brain disease9.9
14breast carcinoma in situ9.9
15chronic lymphocytic leukemia9.9
16in situ carcinoma9.9
17leukemia9.9
18renal cell carcinoma9.9
19schizophrenia9.9
20squamous cell carcinoma9.9

Graphical network of diseases related to Desmoplastic Infantile Ganglioglioma:



Diseases related to desmoplastic infantile ganglioglioma

Clinical Features for Desmoplastic Infantile Ganglioglioma

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Drugs & Therapeutics for Desmoplastic Infantile Ganglioglioma

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Desmoplastic Infantile Ganglioglioma

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Anatomical Context for Desmoplastic Infantile Ganglioglioma

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32MalaCards
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MalaCards organs/tissues related to Desmoplastic Infantile Ganglioglioma:

32
Brain, Parietal lobe

Animal Models for Desmoplastic Infantile Ganglioglioma or affiliated genes

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Publications for Desmoplastic Infantile Ganglioglioma

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Genetic Variations for Desmoplastic Infantile Ganglioglioma

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Expression for genes affiliated with Desmoplastic Infantile Ganglioglioma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Desmoplastic Infantile Ganglioglioma

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Pathways for genes affiliated with Desmoplastic Infantile Ganglioglioma

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Compounds for genes affiliated with Desmoplastic Infantile Ganglioglioma

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB, 28IUPHAR
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Compounds related to Desmoplastic Infantile Ganglioglioma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1valproic acid44 49 11 2412.3MYCN, CP
2agar449.2MYCN, CP
3iron44 2410.2MYCN, CP
4lactate449.1MYCN, CP
5retinoic acid44 2410.1MYCN, CP
6dopamine44 28 11 2412.0CP, MYCN
7vegf448.8CP, MYCN

GO Terms for genes affiliated with Desmoplastic Infantile Ganglioglioma

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Products for genes affiliated with Desmoplastic Infantile Ganglioglioma

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  • Antibodies
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Sources for Desmoplastic Infantile Ganglioglioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet