DIG
MCID: DSM006
MIFTS: 21

Desmoplastic Infantile Ganglioglioma (DIG) malady

Categories: Rare diseases

Aliases & Classifications for Desmoplastic Infantile Ganglioglioma

Aliases & Descriptions for Desmoplastic Infantile Ganglioglioma:

Name: Desmoplastic Infantile Ganglioglioma 50 69
Dig 50

Classifications:



Summaries for Desmoplastic Infantile Ganglioglioma

NIH Rare Diseases : 50 desmoplastic infantile gangliomas (digs) are rare brain tumors that are normally located in the frontal or parietal lobes of the brain. they are usually diagnosed before 18 months of age with most infants presenting with a short duration of symptoms. although seizures are not commonly observed, a bulging fontanelle, rapid head growth, vomiting, and a sunset sign are usually noted. the standard treatment for digs is surgical resection (surgical procedure in which the portion of the brain with the tumor is removed). last updated: 7/30/2013

MalaCards based summary : Desmoplastic Infantile Ganglioglioma, also known as dig, is related to pleomorphic xanthoastrocytoma and ganglioglioma, and has symptoms including seizures An important gene associated with Desmoplastic Infantile Ganglioglioma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include brain and parietal lobe.

Related Diseases for Desmoplastic Infantile Ganglioglioma

Diseases related to Desmoplastic Infantile Ganglioglioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 76)
id Related Disease Score Top Affiliating Genes
1 pleomorphic xanthoastrocytoma 30.0 GFAP SYP
2 ganglioglioma 10.8
3 astrocytoma 10.2
4 papillary tumor of the pineal region 10.1 GFAP SYP
5 brain stem ependymoma 10.1 GFAP SYP
6 intrahepatic bile duct adenoma 10.1 GFAP SYP
7 pilocytic astrocytoma of cerebellum 10.1 GFAP SYP
8 children's interstitial lung disease 10.1 GFAP SYP
9 cervical benign neoplasm 10.1 GFAP SYP
10 myxopapillary ependymoma 10.1 GFAP SYP
11 epidermal appendage tumor 10.1 GFAP SYP
12 microinvasive cervical squamous cell carcinoma 10.1 GFAP SYP
13 clear cell meningioma 10.1 GFAP SYP
14 nephrogenic adenoma of urinary bladder 10.1 GFAP SYP
15 paternal uniparental disomy of chromosome 1 10.1 GFAP SYP
16 cerebral folate receptor alpha deficiency 10.1 GFAP SYP
17 vulvar benign neoplasm 10.1 GFAP SYP
18 adenofibroma 10.1 GFAP SYP
19 pilocytic astrocytoma 10.1 GFAP SYP
20 behcet's syndrome arthropathy 10.1 GFAP SYP
21 blood group incompatibility 10.1 GFAP SYP
22 aneurysm of sinus of valsalva 10.1 GFAP SYP
23 male reproductive system disease 10.1 GFAP SYP
24 mediastinal granular cell myoblastoma 10.1 GFAP SYP
25 central neurocytoma 10.1 GFAP SYP
26 mast-cell sarcoma 10.1 GFAP SYP
27 olfactory neuroblastoma 10.1 GFAP SYP
28 hypogonadotropic hypogonadism-retinitis pigmentosa syndrome 10.1 GFAP SYP
29 superior vena cava syndrome 10.1 GFAP SYP
30 piussan lenaerts mathieu syndrome 10.1 GFAP SYP
31 pneumothorax 10.1 GFAP SYP
32 brain stem astrocytic neoplasm 10.1 GFAP SYP
33 calcific tendinitis 10.1 GFAP SYP
34 auricular cancer 10.1 GFAP SYP
35 dysgerminoma of ovary 10.1 GFAP SYP
36 pediculus humanus corporis infestation 10.1 GFAP SYP
37 brain oligodendroglioma 10.1 GFAP SYP
38 arthus reaction 10.1 GFAP SYP
39 bone dysplasia azouz type 10.1 GFAP SYP
40 pancreatic cancer 10.1 GFAP SYP
41 pacinian tumor 10.1 GFAP SYP
42 temporal lobe neoplasm 10.1 GFAP SYP
43 melanotic neurilemmoma 10.1 GFAP SYP
44 clear cell variant infiltrating bladder urothelial carcinoma 10.1 GFAP SYP
45 inner ear cancer 10.0 GFAP SYP
46 pharynx cancer 10.0 GFAP SYP
47 focal cortical dysplasia, taylor balloon cell type 10.0 GFAP SYP
48 breast squamous cell carcinoma 10.0 GFAP SYP
49 central nervous system hemangioma 10.0 GFAP SYP
50 early myoclonic encephalopathy 10.0 GFAP SYP

Graphical network of the top 20 diseases related to Desmoplastic Infantile Ganglioglioma:



Diseases related to Desmoplastic Infantile Ganglioglioma

Symptoms & Phenotypes for Desmoplastic Infantile Ganglioglioma

UMLS symptoms related to Desmoplastic Infantile Ganglioglioma:


seizures

Drugs & Therapeutics for Desmoplastic Infantile Ganglioglioma

Interventional clinical trials:


id Name Status NCT ID Phase
1 Astrocytoma / Desmoplastic Gamliogliomes (DIA / DIG) - Study of the French Cohort of the Last 20 Years : Clinical, Anatomopathological, Molecular and Radiological Charactersics Recruiting NCT03115164

Search NIH Clinical Center for Desmoplastic Infantile Ganglioglioma

Genetic Tests for Desmoplastic Infantile Ganglioglioma

Anatomical Context for Desmoplastic Infantile Ganglioglioma

MalaCards organs/tissues related to Desmoplastic Infantile Ganglioglioma:

39
Brain, Parietal Lobe

Publications for Desmoplastic Infantile Ganglioglioma

Articles related to Desmoplastic Infantile Ganglioglioma:

(show all 50)
id Title Authors Year
1
Diffusion, Perfusion, and Histopathologic Characteristics of Desmoplastic Infantile Ganglioglioma. ( 27761184 )
2016
2
Desmoplastic infantile ganglioglioma with focal cortical dysplasia: A rare double pathology in an infant with history of seizures. ( 26991995 )
2016
3
Supratentorial tumors typical of the infantile age: desmoplastic infantile ganglioglioma (DIG) and astrocytoma (DIA). A review. ( 27659826 )
2016
4
Desmoplastic infantile ganglioglioma with associated giant aneurysma89case report. ( 25922053 )
2015
5
Malignant transformation of a desmoplastic infantile ganglioglioma in an infant carrier of a nonsynonymous TP53 mutation. ( 24768217 )
2014
6
Desmoplastic infantile ganglioglioma: Report of an unusual case with a cranial defect. ( 24891905 )
2014
7
Desmoplastic infantile ganglioglioma with late presentation. A clinical, radiological and histopathological analysis*. ( 24355183 )
2013
8
Genome-wide DNA copy number analysis of desmoplastic infantile astrocytomas and desmoplastic infantile gangliogliomas. ( 23965740 )
2013
9
Clinical heterogeneity of desmoplastic infantile ganglioglioma: a case series and literature review. ( 22735886 )
2012
10
Strong desmin expression in a congenital desmoplastic infantile ganglioglioma mimicking pleomorphic rhadomyosarcoma: a case report including ultrastructural and cytogenetic evaluation and review of the literature. ( 22899016 )
2012
11
Malignant transformation of a desmoplastic infantile ganglioglioma. ( 21763958 )
2011
12
Desmoplastic infantile ganglioglioma: Report of a case and review of the literature. ( 21042508 )
2010
13
Imaging of desmoplastic infantile ganglioglioma: a spectroscopic viewpoint. ( 19139903 )
2009
14
Desmoplastic infantile ganglioglioma with a malignant course. ( 18352812 )
2008
15
Desmoplastic infantile ganglioglioma: a report of 2 cases and a review of the literature. ( 18703892 )
2008
16
Desmoplastic infantile ganglioglioma: case report. ( 19102059 )
2008
17
Desmoplastic infantile ganglioglioma: novel aspects in clinical presentation and genetics. ( 17719974 )
2007
18
Desmoplastic infantile ganglioglioma. ( 17450367 )
2007
19
Desmoplastic infantile ganglioglioma/astrocytoma with cerebrospinal metastasis. ( 17386372 )
2007
20
Desmoplastic infantile ganglioglioma. Morphological, immunohistochemical and genetic features. ( 16623795 )
2006
21
Desmoplastic infantile ganglioglioma with calcification. ( 16961068 )
2006
22
Case of desmoplastic infantile ganglioglioma secreting ceruloplasmin. ( 16417865 )
2005
23
Desmoplastic infantile ganglioglioma: a questionably benign tumour. ( 16174188 )
2005
24
Atypical MRI appearance of desmoplastic infantile ganglioglioma. ( 15900435 )
2005
25
Desmoplastic Infantile Ganglioglioma: cytologic findings and differential diagnosis on aspiration material. ( 15644137 )
2005
26
Cervico-medullary desmoplastic infantile ganglioglioma: an unusual case with diffuse leptomeningeal dissemination at diagnosis. ( 15702481 )
2005
27
Desmoplastic infantile ganglioglioma with high proliferation index: report of a case. ( 16519002 )
2005
28
Desmoplastic infantile ganglioglioma: a rare tumor with an unusual presentation. ( 15494934 )
2004
29
Desmoplastic infantile ganglioglioma: MRI and histological findings case report. ( 15551129 )
2004
30
Desmoplastic infantile ganglioglioma -- a case report. ( 15472436 )
2004
31
Therapeutic strategies and management of desmoplastic infantile ganglioglioma: two case reports and literature overview. ( 12783262 )
2003
32
Desmoplastic infantile ganglioglioma. ( 12750935 )
2003
33
Desmoplastic infantile ganglioglioma: a potentially malignant tumor? ( 12409729 )
2002
34
Chronological changes on magnetic resonance images in a case of desmoplastic infantile ganglioglioma. ( 11818743 )
2002
35
Desmoplastic infantile ganglioglioma--clinicopathological and immunohistochemical study of four cases. ( 12382166 )
2002
36
Mixed conventional and desmoplastic infantile ganglioglioma: an autopsied case with 6-year follow-up. ( 11455006 )
2001
37
Desmoplastic infantile ganglioglioma (DIG): cranial ultrasound findings. ( 11436886 )
2001
38
Cytologic features of desmoplastic infantile ganglioglioma: a report of two cases. ( 11726100 )
2001
39
Image interpretation session: 1999. Desmoplastic infantile ganglioglioma. ( 10682792 )
2000
40
Desmoplastic infantile ganglioglioma. ( 10508884 )
1999
41
High amino acid uptake in a low-grade desmoplastic infantile ganglioglioma in a 14-year-old patient. ( 9584283 )
1998
42
Desmoplastic infantile ganglioglioma. ( 9408160 )
1997
43
Telomere associations in desmoplastic infantile ganglioglioma. ( 8956861 )
1996
44
Desmoplastic infantile ganglioglioma: CT and MRI features. ( 8545186 )
1995
45
Clinical, radiological and histological findings in desmoplastic infantile ganglioglioma. ( 7842437 )
1994
46
Pleomorphic xanthoastrocytoma and desmoplastic infantile ganglioglioma--have these neoplasms a common origin? ( 7889337 )
1994
47
Desmoplastic infantile ganglioglioma and desmoplastic cerebral astrocytoma of infancy. ( 8293187 )
1993
48
Desmoplastic infantile ganglioglioma with extraparenchymatous cyst--case report. ( 7683126 )
1993
49
Desmoplastic infantile ganglioglioma--case report. ( 7692325 )
1993
50
Desmoplastic infantile ganglioglioma: CT and MR features. ( 1763751 )
1991

Variations for Desmoplastic Infantile Ganglioglioma

Expression for Desmoplastic Infantile Ganglioglioma

Search GEO for disease gene expression data for Desmoplastic Infantile Ganglioglioma.

Pathways for Desmoplastic Infantile Ganglioglioma

Pathways related to Desmoplastic Infantile Ganglioglioma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.31 GFAP MYCN SYP
2 10.86 GFAP SYP

GO Terms for Desmoplastic Infantile Ganglioglioma

Sources for Desmoplastic Infantile Ganglioglioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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