DIG
MCID: DSM006
MIFTS: 21

Desmoplastic Infantile Ganglioglioma (DIG) malady

Category: Rare diseases

Aliases & Classifications for Desmoplastic Infantile Ganglioglioma

About this section

Aliases & Descriptions for Desmoplastic Infantile Ganglioglioma:

Name: Desmoplastic Infantile Ganglioglioma 48 68
 
Dig 48

Classifications:



Summaries for Desmoplastic Infantile Ganglioglioma

About this section
NIH Rare Diseases:48 Desmoplastic infantile gangliomas (digs) are rare brain tumors that are normally located in the frontal or parietal lobes of the brain. they are usually diagnosed before 18 months of age with most infants presenting with a short duration of symptoms. although seizures are not commonly observed, a bulging fontanelle, rapid head growth, vomiting, and a sunset sign are usually noted. the standard treatment for digs is surgical resection (surgical procedure in which the portion of the brain with the tumor is removed). last updated: 7/30/2013

MalaCards based summary: Desmoplastic Infantile Ganglioglioma, also known as DIG, is related to pleomorphic xanthoastrocytoma and ganglioglioma, and has symptoms including seizures An important gene associated with Desmoplastic Infantile Ganglioglioma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways are Neural Stem Cell Differentiation Pathways and Lineage-specific Markers and Neuroscience. Affiliated tissues include parietal lobe and brain.

Related Diseases for Desmoplastic Infantile Ganglioglioma

About this section

Diseases related to Desmoplastic Infantile Ganglioglioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 76)
idRelated DiseaseScoreTop Affiliating Genes
1pleomorphic xanthoastrocytoma30.0GFAP, SYP
2ganglioglioma10.8
3astrocytoma10.2
4papillary tumor of the pineal region10.1GFAP, SYP
5brain stem ependymoma10.1GFAP, SYP
6intrahepatic bile duct adenoma10.1GFAP, SYP
7pilocytic astrocytoma of cerebellum10.1GFAP, SYP
8children's interstitial lung disease10.1GFAP, SYP
9cervical benign neoplasm10.1GFAP, SYP
10myxopapillary ependymoma10.1GFAP, SYP
11epidermal appendage tumor10.1GFAP, SYP
12microinvasive cervical squamous cell carcinoma10.1GFAP, SYP
13clear cell meningioma10.1GFAP, SYP
14nephrogenic adenoma of urinary bladder10.1GFAP, SYP
15paternal uniparental disomy of chromosome 110.1GFAP, SYP
16cerebral folate receptor alpha deficiency10.1GFAP, SYP
17vulvar benign neoplasm10.1GFAP, SYP
18adenofibroma10.1GFAP, SYP
19pilocytic astrocytoma10.1GFAP, SYP
20behcet's syndrome arthropathy10.1GFAP, SYP
21blood group incompatibility10.1GFAP, SYP
22aneurysm of sinus of valsalva10.1GFAP, SYP
23male reproductive system disease10.1GFAP, SYP
24mediastinal granular cell myoblastoma10.1GFAP, SYP
25central neurocytoma10.1GFAP, SYP
26mast-cell sarcoma10.1GFAP, SYP
27olfactory neuroblastoma10.1GFAP, SYP
28hypogonadotropic hypogonadism-retinitis pigmentosa syndrome10.1GFAP, SYP
29superior vena cava syndrome10.1GFAP, SYP
30piussan lenaerts mathieu syndrome10.1GFAP, SYP
31pneumothorax10.1GFAP, SYP
32brain stem astrocytic neoplasm10.1GFAP, SYP
33calcific tendinitis10.1GFAP, SYP
34auricular cancer10.1GFAP, SYP
35dysgerminoma of ovary10.1GFAP, SYP
36pediculus humanus corporis infestation10.1GFAP, SYP
37brain oligodendroglioma10.1GFAP, SYP
38arthus reaction10.1GFAP, SYP
39bone dysplasia azouz type10.1GFAP, SYP
40pancreatic cancer10.1GFAP, SYP
41pacinian tumor10.1GFAP, SYP
42temporal lobe neoplasm10.1GFAP, SYP
43melanotic neurilemmoma10.1GFAP, SYP
44clear cell variant infiltrating bladder urothelial carcinoma10.1GFAP, SYP
45inner ear cancer10.0GFAP, SYP
46pharynx cancer10.0GFAP, SYP
47focal cortical dysplasia, taylor balloon cell type10.0GFAP, SYP
48breast squamous cell carcinoma10.0GFAP, SYP
49central nervous system hemangioma10.0GFAP, SYP
50early myoclonic encephalopathy10.0GFAP, SYP

Graphical network of the top 20 diseases related to Desmoplastic Infantile Ganglioglioma:



Diseases related to desmoplastic infantile ganglioglioma

Symptoms & Phenotypes for Desmoplastic Infantile Ganglioglioma

About this section

UMLS symptoms related to Desmoplastic Infantile Ganglioglioma:


seizures

Drugs & Therapeutics for Desmoplastic Infantile Ganglioglioma

About this section

Interventional clinical trials:

idNameStatusNCT IDPhase
1Astrocytoma / Desmoplastic Gamliogliomes (DIA / DIG) - Study of the French Cohort of the Last 20 Years : Clinical, Anatomopathological, Molecular and Radiological CharactersicsRecruitingNCT03115164

Search NIH Clinical Center for Desmoplastic Infantile Ganglioglioma

Genetic Tests for Desmoplastic Infantile Ganglioglioma

About this section

Anatomical Context for Desmoplastic Infantile Ganglioglioma

About this section

MalaCards organs/tissues related to Desmoplastic Infantile Ganglioglioma:

36
Parietal lobe, Brain

Publications for Desmoplastic Infantile Ganglioglioma

About this section

Articles related to Desmoplastic Infantile Ganglioglioma:

(show all 50)
idTitleAuthorsYear
1
Diffusion, Perfusion, and Histopathologic Characteristics of Desmoplastic Infantile Ganglioglioma. (27761184)
2016
2
Desmoplastic infantile ganglioglioma with focal cortical dysplasia: A rare double pathology in an infant with history of seizures. (26991995)
2016
3
Supratentorial tumors typical of the infantile age: desmoplastic infantile ganglioglioma (DIG) and astrocytoma (DIA). A review. (27659826)
2016
4
Desmoplastic infantile ganglioglioma with associated giant aneurysma89case report. (25922053)
2015
5
Malignant transformation of a desmoplastic infantile ganglioglioma in an infant carrier of a nonsynonymous TP53 mutation. (24768217)
2014
6
Desmoplastic infantile ganglioglioma: Report of an unusual case with a cranial defect. (24891905)
2014
7
Desmoplastic infantile ganglioglioma with late presentation. A clinical, radiological and histopathological analysis*. (24355183)
2013
8
Genome-wide DNA copy number analysis of desmoplastic infantile astrocytomas and desmoplastic infantile gangliogliomas. (23965740)
2013
9
Clinical heterogeneity of desmoplastic infantile ganglioglioma: a case series and literature review. (22735886)
2012
10
Strong desmin expression in a congenital desmoplastic infantile ganglioglioma mimicking pleomorphic rhadomyosarcoma: a case report including ultrastructural and cytogenetic evaluation and review of the literature. (22899016)
2012
11
Malignant transformation of a desmoplastic infantile ganglioglioma. (21763958)
2011
12
Desmoplastic infantile ganglioglioma: Report of a case and review of the literature. (21042508)
2010
13
Imaging of desmoplastic infantile ganglioglioma: a spectroscopic viewpoint. (19139903)
2009
14
Desmoplastic infantile ganglioglioma with a malignant course. (18352812)
2008
15
Desmoplastic infantile ganglioglioma: a report of 2 cases and a review of the literature. (18703892)
2008
16
Desmoplastic infantile ganglioglioma: case report. (19102059)
2008
17
Desmoplastic infantile ganglioglioma: novel aspects in clinical presentation and genetics. (17719974)
2007
18
Desmoplastic infantile ganglioglioma. (17450367)
2007
19
Desmoplastic infantile ganglioglioma/astrocytoma with cerebrospinal metastasis. (17386372)
2007
20
Desmoplastic infantile ganglioglioma. Morphological, immunohistochemical and genetic features. (16623795)
2006
21
Desmoplastic infantile ganglioglioma with calcification. (16961068)
2006
22
Case of desmoplastic infantile ganglioglioma secreting ceruloplasmin. (16417865)
2005
23
Desmoplastic infantile ganglioglioma: a questionably benign tumour. (16174188)
2005
24
Atypical MRI appearance of desmoplastic infantile ganglioglioma. (15900435)
2005
25
Desmoplastic Infantile Ganglioglioma: cytologic findings and differential diagnosis on aspiration material. (15644137)
2005
26
Cervico-medullary desmoplastic infantile ganglioglioma: an unusual case with diffuse leptomeningeal dissemination at diagnosis. (15702481)
2005
27
Desmoplastic infantile ganglioglioma with high proliferation index: report of a case. (16519002)
2005
28
Desmoplastic infantile ganglioglioma: a rare tumor with an unusual presentation. (15494934)
2004
29
Desmoplastic infantile ganglioglioma: MRI and histological findings case report. (15551129)
2004
30
Desmoplastic infantile ganglioglioma -- a case report. (15472436)
2004
31
Therapeutic strategies and management of desmoplastic infantile ganglioglioma: two case reports and literature overview. (12783262)
2003
32
Desmoplastic infantile ganglioglioma. (12750935)
2003
33
Desmoplastic infantile ganglioglioma: a potentially malignant tumor? (12409729)
2002
34
Chronological changes on magnetic resonance images in a case of desmoplastic infantile ganglioglioma. (11818743)
2002
35
Desmoplastic infantile ganglioglioma--clinicopathological and immunohistochemical study of four cases. (12382166)
2002
36
Mixed conventional and desmoplastic infantile ganglioglioma: an autopsied case with 6-year follow-up. (11455006)
2001
37
Desmoplastic infantile ganglioglioma (DIG): cranial ultrasound findings. (11436886)
2001
38
Cytologic features of desmoplastic infantile ganglioglioma: a report of two cases. (11726100)
2001
39
Image interpretation session: 1999. Desmoplastic infantile ganglioglioma. (10682792)
2000
40
Desmoplastic infantile ganglioglioma. (10508884)
1999
41
High amino acid uptake in a low-grade desmoplastic infantile ganglioglioma in a 14-year-old patient. (9584283)
1998
42
Desmoplastic infantile ganglioglioma. (9408160)
1997
43
Telomere associations in desmoplastic infantile ganglioglioma. (8956861)
1996
44
Desmoplastic infantile ganglioglioma: CT and MRI features. (8545186)
1995
45
Clinical, radiological and histological findings in desmoplastic infantile ganglioglioma. (7842437)
1994
46
Pleomorphic xanthoastrocytoma and desmoplastic infantile ganglioglioma--have these neoplasms a common origin? (7889337)
1994
47
Desmoplastic infantile ganglioglioma and desmoplastic cerebral astrocytoma of infancy. (8293187)
1993
48
Desmoplastic infantile ganglioglioma with extraparenchymatous cyst--case report. (7683126)
1993
49
Desmoplastic infantile ganglioglioma--case report. (7692325)
1993
50
Desmoplastic infantile ganglioglioma: CT and MR features. (1763751)
1991

Variations for Desmoplastic Infantile Ganglioglioma

About this section

Expression for genes affiliated with Desmoplastic Infantile Ganglioglioma

About this section
Search GEO for disease gene expression data for Desmoplastic Infantile Ganglioglioma.

Pathways for genes affiliated with Desmoplastic Infantile Ganglioglioma

About this section

Pathways related to Desmoplastic Infantile Ganglioglioma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3GFAP, SYP
28.5GFAP, MYCN, SYP

GO Terms for genes affiliated with Desmoplastic Infantile Ganglioglioma

About this section

Sources for Desmoplastic Infantile Ganglioglioma

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet