MCID: DSM006
MIFTS: 24

Desmoplastic Infantile Ganglioglioma

Categories: Rare diseases

Aliases & Classifications for Desmoplastic Infantile Ganglioglioma

MalaCards integrated aliases for Desmoplastic Infantile Ganglioglioma:

Name: Desmoplastic Infantile Ganglioglioma 49 69
Dig 49

Classifications:



External Ids:

UMLS 69 C1321878

Summaries for Desmoplastic Infantile Ganglioglioma

NIH Rare Diseases : 49 Desmoplastic infantile gangliomas (DIGs) are rare brain tumors that are normally located in the frontal or parietal lobes of the brain. They are usually diagnosed before 18 months of age with most infants presenting with a short duration of symptoms. Although seizures are not commonly observed, a bulging fontanelle, rapid head growth, vomiting, and a sunset sign are usually noted. The standard treatment for DIGs is surgical resection (surgical procedure in which the portion of the brain with the tumor is removed). Last updated: 7/30/2013

MalaCards based summary : Desmoplastic Infantile Ganglioglioma, also known as dig, is related to ganglioglioma and pleomorphic xanthoastrocytoma, and has symptoms including seizures An important gene associated with Desmoplastic Infantile Ganglioglioma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include parietal lobe and brain.

Related Diseases for Desmoplastic Infantile Ganglioglioma

Diseases related to Desmoplastic Infantile Ganglioglioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
# Related Disease Score Top Affiliating Genes
1 ganglioglioma 31.2 GFAP SYP
2 pleomorphic xanthoastrocytoma 30.1 GFAP SYP
3 astrocytoma 30.1 GFAP SYP
4 extraventricular neurocytoma 10.1 GFAP SYP
5 lung combined type small cell carcinoma 10.1 GFAP SYP
6 cellular ependymoma 10.1 GFAP SYP
7 gangliocytoma 10.1 GFAP SYP
8 rhabdoid meningioma 10.1 GFAP SYP
9 pilomyxoid astrocytoma 10.1 GFAP SYP
10 chordoid meningioma 10.1 GFAP SYP
11 central nervous system primitive neuroectodermal neoplasm 10.1 GFAP SYP
12 subependymal glioma 10.1 GFAP SYP
13 chiari malformation 10.1 GFAP SYP
14 dysembryoplastic neuroepithelial tumor 10.1 GFAP SYP
15 cerebral neuroblastoma 10.1 GFAP SYP
16 benign ependymoma 10.1 GFAP SYP
17 astroblastoma 10.1 GFAP SYP
18 cerebral ventricle cancer 10.1 GFAP SYP
19 cerebrum cancer 10.1 GFAP SYP
20 pineal gland cancer 10.1 GFAP SYP
21 melanotic neuroectodermal tumor 10.1 GFAP SYP
22 anaplastic ependymoma 10.1 GFAP SYP
23 subependymoma 10.1 GFAP SYP
24 angiocentric glioma 10.1 GFAP SYP
25 obstructive hydrocephalus 10.0 GFAP SYP
26 supratentorial cancer 10.0 GFAP SYP
27 medulloepithelioma 10.0 GFAP SYP
28 pineocytoma 10.0 GFAP SYP
29 pineoblastoma 10.0 GFAP SYP
30 childhood oligodendroglioma 10.0 GFAP SYP
31 tanycytic ependymoma 10.0 GFAP SYP
32 papillary ependymoma 10.0 GFAP SYP
33 papilloma of choroid plexus 10.0 GFAP SYP
34 subependymal giant cell astrocytoma 10.0 GFAP SYP
35 central neurocytoma 10.0 GFAP SYP
36 binswanger's disease 10.0 GFAP SYP
37 atypical teratoid rhabdoid tumor 10.0 GFAP SYP
38 cystic teratoma 10.0 GFAP SYP
39 cerebellopontine angle tumor 10.0 GFAP SYP
40 cerebellar liponeurocytoma 10.0 GFAP SYP
41 aging 10.0
42 cerebritis 10.0
43 desmoplastic infantile astrocytoma 10.0
44 pancreatic gastrinoma 10.0 GFAP SYP
45 clear cell ependymoma 10.0 GFAP SYP
46 optic nerve glioma 10.0 GFAP SYP
47 ependymoma 10.0 GFAP SYP
48 giant cell glioblastoma 9.9 GFAP SYP
49 hemangioblastoma 9.9 GFAP SYP
50 teratoma 9.9 GFAP SYP

Graphical network of the top 20 diseases related to Desmoplastic Infantile Ganglioglioma:



Diseases related to Desmoplastic Infantile Ganglioglioma

Symptoms & Phenotypes for Desmoplastic Infantile Ganglioglioma

UMLS symptoms related to Desmoplastic Infantile Ganglioglioma:


seizures

Drugs & Therapeutics for Desmoplastic Infantile Ganglioglioma

Search Clinical Trials , NIH Clinical Center for Desmoplastic Infantile Ganglioglioma

Genetic Tests for Desmoplastic Infantile Ganglioglioma

Anatomical Context for Desmoplastic Infantile Ganglioglioma

MalaCards organs/tissues related to Desmoplastic Infantile Ganglioglioma:

38
Parietal Lobe, Brain

Publications for Desmoplastic Infantile Ganglioglioma

Articles related to Desmoplastic Infantile Ganglioglioma:

(show all 50)
# Title Authors Year
1
Diffusion, Perfusion, and Histopathologic Characteristics of Desmoplastic Infantile Ganglioglioma. ( 27761184 )
2016
2
Desmoplastic infantile ganglioglioma with focal cortical dysplasia: A rare double pathology in an infant with history of seizures. ( 26991995 )
2016
3
Supratentorial tumors typical of the infantile age: desmoplastic infantile ganglioglioma (DIG) and astrocytoma (DIA). A review. ( 27659826 )
2016
4
Desmoplastic infantile ganglioglioma with associated giant aneurysma89case report. ( 25922053 )
2015
5
Malignant transformation of a desmoplastic infantile ganglioglioma in an infant carrier of a nonsynonymous TP53 mutation. ( 24768217 )
2014
6
Desmoplastic infantile ganglioglioma: Report of an unusual case with a cranial defect. ( 24891905 )
2014
7
Desmoplastic infantile ganglioglioma with late presentation. A clinical, radiological and histopathological analysis*. ( 24355183 )
2013
8
Genome-wide DNA copy number analysis of desmoplastic infantile astrocytomas and desmoplastic infantile gangliogliomas. ( 23965740 )
2013
9
Clinical heterogeneity of desmoplastic infantile ganglioglioma: a case series and literature review. ( 22735886 )
2012
10
Strong desmin expression in a congenital desmoplastic infantile ganglioglioma mimicking pleomorphic rhadomyosarcoma: a case report including ultrastructural and cytogenetic evaluation and review of the literature. ( 22899016 )
2012
11
Malignant transformation of a desmoplastic infantile ganglioglioma. ( 21763958 )
2011
12
Desmoplastic infantile ganglioglioma: Report of a case and review of the literature. ( 21042508 )
2010
13
Imaging of desmoplastic infantile ganglioglioma: a spectroscopic viewpoint. ( 19139903 )
2009
14
Desmoplastic infantile ganglioglioma: a report of 2 cases and a review of the literature. ( 18703892 )
2008
15
Desmoplastic infantile ganglioglioma: case report. ( 19102059 )
2008
16
Desmoplastic infantile ganglioglioma with a malignant course. ( 18352812 )
2008
17
Desmoplastic infantile ganglioglioma: novel aspects in clinical presentation and genetics. ( 17719974 )
2007
18
Desmoplastic infantile ganglioglioma/astrocytoma with cerebrospinal metastasis. ( 17386372 )
2007
19
Desmoplastic infantile ganglioglioma. ( 17450367 )
2007
20
Desmoplastic infantile ganglioglioma. Morphological, immunohistochemical and genetic features. ( 16623795 )
2006
21
Desmoplastic infantile ganglioglioma with calcification. ( 16961068 )
2006
22
Desmoplastic infantile ganglioglioma: a questionably benign tumour. ( 16174188 )
2005
23
Desmoplastic infantile ganglioglioma with high proliferation index: report of a case. ( 16519002 )
2005
24
Cervico-medullary desmoplastic infantile ganglioglioma: an unusual case with diffuse leptomeningeal dissemination at diagnosis. ( 15702481 )
2005
25
Atypical MRI appearance of desmoplastic infantile ganglioglioma. ( 15900435 )
2005
26
Desmoplastic Infantile Ganglioglioma: cytologic findings and differential diagnosis on aspiration material. ( 15644137 )
2005
27
Case of desmoplastic infantile ganglioglioma secreting ceruloplasmin. ( 16417865 )
2005
28
Desmoplastic infantile ganglioglioma: a rare tumor with an unusual presentation. ( 15494934 )
2004
29
Desmoplastic infantile ganglioglioma -- a case report. ( 15472436 )
2004
30
Desmoplastic infantile ganglioglioma: MRI and histological findings case report. ( 15551129 )
2004
31
Therapeutic strategies and management of desmoplastic infantile ganglioglioma: two case reports and literature overview. ( 12783262 )
2003
32
Desmoplastic infantile ganglioglioma. ( 12750935 )
2003
33
Desmoplastic infantile ganglioglioma--clinicopathological and immunohistochemical study of four cases. ( 12382166 )
2002
34
Chronological changes on magnetic resonance images in a case of desmoplastic infantile ganglioglioma. ( 11818743 )
2002
35
Desmoplastic infantile ganglioglioma: a potentially malignant tumor? ( 12409729 )
2002
36
Mixed conventional and desmoplastic infantile ganglioglioma: an autopsied case with 6-year follow-up. ( 11455006 )
2001
37
Desmoplastic infantile ganglioglioma (DIG): cranial ultrasound findings. ( 11436886 )
2001
38
Cytologic features of desmoplastic infantile ganglioglioma: a report of two cases. ( 11726100 )
2001
39
Image interpretation session: 1999. Desmoplastic infantile ganglioglioma. ( 10682792 )
2000
40
Desmoplastic infantile ganglioglioma. ( 10508884 )
1999
41
High amino acid uptake in a low-grade desmoplastic infantile ganglioglioma in a 14-year-old patient. ( 9584283 )
1998
42
Desmoplastic infantile ganglioglioma. ( 9408160 )
1997
43
Telomere associations in desmoplastic infantile ganglioglioma. ( 8956861 )
1996
44
Desmoplastic infantile ganglioglioma: CT and MRI features. ( 8545186 )
1995
45
Clinical, radiological and histological findings in desmoplastic infantile ganglioglioma. ( 7842437 )
1994
46
Pleomorphic xanthoastrocytoma and desmoplastic infantile ganglioglioma--have these neoplasms a common origin? ( 7889337 )
1994
47
Desmoplastic infantile ganglioglioma with extraparenchymatous cyst--case report. ( 7683126 )
1993
48
Desmoplastic infantile ganglioglioma--case report. ( 7692325 )
1993
49
Desmoplastic infantile ganglioglioma and desmoplastic cerebral astrocytoma of infancy. ( 8293187 )
1993
50
Desmoplastic infantile ganglioglioma: CT and MR features. ( 1763751 )
1991

Variations for Desmoplastic Infantile Ganglioglioma

Expression for Desmoplastic Infantile Ganglioglioma

Search GEO for disease gene expression data for Desmoplastic Infantile Ganglioglioma.

Pathways for Desmoplastic Infantile Ganglioglioma

Pathways related to Desmoplastic Infantile Ganglioglioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.33 GFAP MYCN SYP
2 10.85 GFAP SYP

GO Terms for Desmoplastic Infantile Ganglioglioma

Molecular functions related to Desmoplastic Infantile Ganglioglioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 kinase binding GO:0019900 8.62 GFAP MYCN

Sources for Desmoplastic Infantile Ganglioglioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
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29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
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35 IUPHAR
36 KEGG
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42 MESH via Orphanet
43 MGI
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46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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