DSRCT
MCID: DSM007
MIFTS: 47

Desmoplastic Small Round Cell Tumor (DSRCT) malady

Categories: Rare diseases

Aliases & Classifications for Desmoplastic Small Round Cell Tumor

Aliases & Descriptions for Desmoplastic Small Round Cell Tumor:

Name: Desmoplastic Small Round Cell Tumor 50 56 69
Desmoplastic Small Round-Cell Tumor 50 52
Dsrct 50 56

Characteristics:

Orphanet epidemiological data:

56
desmoplastic small round cell tumor
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe); Age of onset: Adolescent,Adult;

Classifications:



External Ids:

Orphanet 56 ORPHA83469
MESH via Orphanet 43 D058405
UMLS via Orphanet 70 C0281508
ICD10 via Orphanet 34 C48.2

Summaries for Desmoplastic Small Round Cell Tumor

NIH Rare Diseases : 50 desmoplastic small round cell tumor (dsrct) is a rare type of soft tissue cancer (sarcoma) that usually begins in the abdomen. it primarily affects children and young adults and is more common in males. it is formed by small, round cancer cells surrounded by scar-like tissue and is often found in the tissue (peritoneum) that lines the inside of the abdomen and pelvis. the tumor cells have a characteristic genetic change involving a translocation between chromosomes 11 and 22, which is important in differentiating from other similar tumors. the genetic change involved in dsrct is acquired throughout a person's lifetime and is not inherited. symptoms may include abdominal pain and a feeling of fullness, abdominal mass, and symptoms of gastrointestinal obstruction, such as constipation. treatment options may include: chemotherapy, radiation therapy, surgery, and stem cell transplantation. last updated: 9/9/2016

MalaCards based summary : Desmoplastic Small Round Cell Tumor, also known as desmoplastic small round-cell tumor, is related to plexopathy and gastrointestinal stromal tumor, and has symptoms including cachexia, abdominal pain and nausea and vomiting. An important gene associated with Desmoplastic Small Round Cell Tumor is EWSR1 (EWS RNA Binding Protein 1), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Doxorubicin and Vincristine have been mentioned in the context of this disorder. Affiliated tissues include lung, ovary and bone, and related phenotype is respiratory system.

Wikipedia : 71 Desmoplastic small-round-cell tumor is an aggressive and rare cancer that primarily occurs as masses in... more...

Related Diseases for Desmoplastic Small Round Cell Tumor

Diseases related to Desmoplastic Small Round Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 222)
id Related Disease Score Top Affiliating Genes
1 plexopathy 29.9 CD99 ENO2 EWSR1 PTPRC WT1
2 gastrointestinal stromal tumor 29.2 ACTC1 CHGA DES ENO2 S100B SYP
3 sarcoma 10.5
4 inflammatory linear verrucous epidermal nevus 10.3 DES VIM
5 mitral valve disease 10.3 ALPP ENO2
6 liver angiosarcoma 10.3 DES VIM WT1
7 painful legs and moving toes syndrome 10.3 ALPP ENO2
8 marfanoid hypermobility syndrome 10.3 DES MUC1 VIM
9 vitreous syneresis 10.3 CD99 EWSR1
10 tanycytic ependymoma 10.3 DES MUC1 VIM
11 pituitary hypoplasia 10.3 ALPP ENO2
12 adult endodermal sinus tumor 10.3 DES ENO2 VIM
13 male reproductive system disease 10.3 DES SYP VIM
14 anal gland neoplasm 10.3 DES MUC1 VIM
15 skeletal-extraskeletal angiomatosis 10.3 ENO2 MUC1 SYP
16 nephrogenic adenoma of urinary bladder 10.3 ENO2 SYP VIM
17 gallbladder pleomorphic giant cell adenocarcinoma 10.3 ENO2 SYP WT1
18 infiltrating renal pelvis transitional cell carcinoma 10.3 ENO2 SYP
19 lucey-driscoll syndrome 10.3 MUC1 S100B
20 secondary pulmonary hemosiderosis 10.3 MUC1 S100B
21 differentiating neuroblastoma 10.3 ENO2 MUC1 VIM
22 thymoma 10.3 ENO2 MUC1 SYP
23 jewett-marshall bladder cancer 10.3 DES ENO2 VIM
24 blood group incompatibility 10.3 CSF3 ENO2 SYP
25 heart leiomyosarcoma 10.3 DES MYOG
26 acute stress disorder 10.3 ENO2 SYP WT1
27 lupus - neurological sequelae 10.3 S100B VIM
28 mixed type rhabdomyosarcoma 10.3 DES MYOD1 MYOG
29 pneumonia 10.3 ALPP ENO2 WT1
30 lymphomatous thyroiditis 10.3 DES VIM
31 testis sarcoma 10.3 DES MYOD1 MYOG
32 endocardium cancer 10.3 EWSR1 MUC1 S100B
33 cavernous sinus meningioma 10.3 DES S100B VIM
34 postgerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma 10.3 MUC1 S100B VIM
35 benign schwannoma 10.3 ENO2 S100B VIM
36 subglottis verrucous carcinoma 10.3 MUC1 S100B VIM
37 clear cell ependymoma 10.3 MUC1 S100B VIM
38 myelinoclastic diffuse sclerosis 10.3 ENO2 MUC1 S100B
39 sternum cancer 10.2 MUC1 S100B VIM
40 gestational trophoblastic neoplasm 10.2 MUC1 SYP VIM WT1
41 brain stem infarction 10.2 MYOD1 MYOG WT1
42 bone deterioration disease 10.2 DES S100B SYP
43 lymphomatoid papulosis 10.2 ACTC1 VIM
44 hormone producing pituitary cancer 10.2 MYOD1 MYOG WT1
45 intrahepatic bile duct cystadenoma 10.2 DES MYOD1 S100B
46 extranodal nasal nk/t cell lymphoma 10.2 CSF3 EWSR1 FLI1
47 malignant mixed mullerian tumor 10.2 DES ENO2
48 polydactyly cleft lip palate psychomotor retardation 10.2 DES MUC1 PTPRC
49 autosomal recessive stickler syndrome 10.2 ENO2 MUC1 SYP VIM
50 invasive mole 10.2 MUC1 S100B

Graphical network of the top 20 diseases related to Desmoplastic Small Round Cell Tumor:



Diseases related to Desmoplastic Small Round Cell Tumor

Symptoms & Phenotypes for Desmoplastic Small Round Cell Tumor

Human phenotypes related to Desmoplastic Small Round Cell Tumor:

56 32 (show all 18)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 cachexia 56 32 Occasional (29-5%) HP:0004326
2 abdominal pain 56 32 Very frequent (99-80%) HP:0002027
3 nausea and vomiting 56 32 Frequent (79-30%) HP:0002017
4 hepatomegaly 56 32 Frequent (79-30%) HP:0002240
5 ascites 56 32 Occasional (29-5%) HP:0001541
6 anemia 56 32 Occasional (29-5%) HP:0001903
7 ileus 56 32 Frequent (79-30%) HP:0002595
8 neoplasm of the central nervous system 56 32 Occasional (29-5%) HP:0100006
9 sarcoma 56 32 Very frequent (99-80%) HP:0100242
10 ovarian neoplasm 56 32 Occasional (29-5%) HP:0100615
11 mediastinal lymphadenopathy 56 32 Frequent (79-30%) HP:0100721
12 neoplasm of the pancreas 56 32 Occasional (29-5%) HP:0002894
13 neoplasm of the lung 56 32 Occasional (29-5%) HP:0100526
14 abdominal distention 56 32 Very frequent (99-80%) HP:0003270
15 testicular neoplasm 56 32 Occasional (29-5%) HP:0010788
16 abnormality of the peritoneum 56 32 Very frequent (99-80%) HP:0002585
17 weight loss 56 Frequent (79-30%)
18 lymphadenopathy 56 Very frequent (99-80%)

UMLS symptoms related to Desmoplastic Small Round Cell Tumor:


pain

MGI Mouse Phenotypes related to Desmoplastic Small Round Cell Tumor:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 respiratory system MP:0005388 9.17 WT1 ENO2 MYOD1 MYOG PTPRC THBD

Drugs & Therapeutics for Desmoplastic Small Round Cell Tumor

Drugs for Desmoplastic Small Round Cell Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 105)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 2, Phase 3,Phase 1 23214-92-8 31703
2
Vincristine Approved, Investigational Phase 3,Phase 2 2068-78-2, 57-22-7 5978
3
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
4
Carboplatin Approved Phase 3,Phase 2 41575-94-4 10339178 498142 38904
5
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
6
Ifosfamide Approved Phase 3,Phase 2 3778-73-2 3690
7
Dactinomycin Approved Phase 3,Phase 2 50-76-0 2019 457193
8
Epirubicin Approved Phase 3,Phase 2 56420-45-2 41867
9
Trabectedin Approved, Investigational Phase 2, Phase 3 114899-77-3 108150
10
Doxil Approved June 1999 Phase 2, Phase 3,Phase 1 31703
11 Alkylating Agents Phase 3,Phase 2,Phase 1
12 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
13 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
14 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
15 Etoposide phosphate Phase 3,Phase 2
16 Anti-Infective Agents Phase 3,Phase 2,Phase 1
17 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
18 Isophosphamide mustard Phase 3,Phase 2
19 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
20 Antimitotic Agents Phase 3,Phase 2
21 Antirheumatic Agents Phase 3,Phase 2
22 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1
23 Antineoplastic Agents, Phytogenic Phase 3,Phase 2
24
Cyclosporine Approved, Investigational, Vet_approved Phase 2 79217-60-0, 59865-13-3 5284373 6435893
25
Tacrolimus Approved, Investigational Phase 2 104987-11-3 445643 439492
26
Cisplatin Approved Phase 2,Phase 1 15663-27-1 84093 441203 2767
27
Topotecan Approved, Investigational Phase 2 119413-54-6, 123948-87-8 60700
28
Melphalan Approved Phase 2,Phase 1 148-82-3 4053 460612
29
Fludarabine Approved Phase 2,Phase 1 21679-14-1, 75607-67-9 30751
30
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
31
Mechlorethamine Approved Phase 2 51-75-2 4033
32
Everolimus Approved Phase 2 159351-69-6 6442177
33
Thiotepa Approved Phase 2,Phase 1 52-24-4 5453
34
Lenograstim Approved Phase 2,Phase 1 135968-09-1
35
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
36
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030 46835353
37
Arsenic trioxide Approved, Investigational Phase 2 1327-53-3 518740
38
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
39
Gemcitabine Approved Phase 2 95058-81-4 60750
40
Aldesleukin Approved Phase 1, Phase 2 85898-30-2, 110942-02-4
41
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
42
Irinotecan Approved, Investigational Phase 2 97682-44-5, 100286-90-6 60838
43
Acetaminophen Approved Phase 2 103-90-2 1983
44
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
45
Diphenhydramine Approved Phase 2 58-73-1, 147-24-0 3100
46
Temozolomide Approved, Investigational Phase 2 85622-93-1 5394
47
Promethazine Approved Phase 2 60-87-7 4927
48
Bevacizumab Approved, Investigational Phase 2 216974-75-3
49
nivolumab Approved Phase 2 946414-94-4
50
Vitamin C Approved, Nutraceutical Phase 2 50-81-7 5785 54670067

Interventional clinical trials:

(show all 41)
id Name Status NCT ID Phase
1 Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00002898 Phase 3
2 Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma Terminated NCT01189253 Phase 2, Phase 3
3 Imatinib Mesylate in Patients With Refractory Desmoplastic Small Round Cell Tumors Completed NCT00417807 Phase 1, Phase 2
4 QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors Completed NCT00563680 Phase 2
5 Imatinib Mesylate in Treating Patients With Recurrent Ewing's Family of Tumors or Desmoplastic Small Round-Cell Tumor Completed NCT00062205 Phase 2
6 Exatecan Mesylate in Treating Patients With Ewing's Sarcoma, Primitive Neuroectodermal Tumor, or Desmoplastic Small Round Cell Tumor Completed NCT00055952 Phase 2
7 A Study of R1507 in Participants With Recurrent or Refractory Sarcoma Completed NCT00642941 Phase 2
8 Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood Completed NCT00030667 Phase 2
9 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2
10 Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas Completed NCT00043979 Phase 2
11 Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors Completed NCT00024258 Phase 2
12 Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer Completed NCT00002515 Phase 2
13 Combination Chemotherapy and Radiation Therapy in Treating Patients With Peripheral Neuroectodermal Tumors, Ewing's Sarcoma, Wilms' Tumor, or Bone Cancer Completed NCT00002466 Phase 2
14 BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors Completed NCT00526149 Phase 2
15 Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas Completed NCT00474994 Phase 2
16 Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors Completed NCT00025441 Phase 2
17 Activated T Cells Armed With GD2 Bispecific Antibody in Children and Young Adults With Neuroblastoma and Osteosarcoma Recruiting NCT02173093 Phase 1, Phase 2
18 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma Recruiting NCT01532687 Phase 2
19 Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors Active, not recruiting NCT01946529 Phase 2
20 Pilot Study of Hyperthermic Peritoneal Perfusion (HIPEC) for Adolescent and Young Adults With Desmoplastic Small Round Cell Tumor Active, not recruiting NCT01277744 Phase 2
21 Therapy to Treat Ewing's Sarcoma, Rhabdomyosarcoma or Neuroblastoma Active, not recruiting NCT00923351 Phase 1, Phase 2
22 Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer Active, not recruiting NCT00445965 Phase 2
23 A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma Not yet recruiting NCT02982486 Phase 2
24 Study of High Dose Intravenous (IV) Ascorbic Acid in Measurable Solid Tumor Disease Suspended NCT01125449 Phase 2
25 Tanespimycin in Treating Young Patients With Recurrent or Refractory Leukemia or Solid Tumors Completed NCT00093821 Phase 1
26 Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin for Children With Peritoneal Cancer Completed NCT00436657 Phase 1
27 Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma Completed NCT00720174 Phase 1
28 AMG-479 in Treating Patients With Advanced Solid Tumors or Non-Hodgkin Lymphoma Completed NCT00562380 Phase 1
29 Intraperitoneal Radioimmunotherapy With 131I-8H9 for Patients With Desmoplastic Small Round Cell Tumors and Other Solid Tumors Involving the Peritoneum Recruiting NCT01099644 Phase 1
30 Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors Recruiting NCT02982941 Phase 1
31 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer Recruiting NCT00089245 Phase 1
32 Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors Terminated NCT00003926 Phase 1
33 Studying Genes in Samples From Younger Patients With Desmoplastic Small Round Cell Tumor Registered on COG-D9902 or COG-ABTR01B1 Completed NCT01430637
34 Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas Completed NCT01567046
35 Combination Chemotherapy in Treating Patients With Sarcoma Completed NCT00662233
36 Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Recruiting NCT00919269
37 Understanding Communication in Healthcare to Achieve Trust (U-CHAT) Recruiting NCT02846038
38 Irinotecan, Temozolomide and Bevacizumab in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Newly Diagnosed Patients With Desmoplastic Small Round Cell Tumor Active, not recruiting NCT01189643
39 French National Registry of Rare Peritoneal Surface Malignancies Active, not recruiting NCT02834169
40 Quality of Life Study for Pediatric and Adult Patients Undergoing Hyperthermic Peritoneal Perfusion With Cisplatin Active, not recruiting NCT00502177
41 Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma Withdrawn NCT00334984

Search NIH Clinical Center for Desmoplastic Small Round Cell Tumor

Genetic Tests for Desmoplastic Small Round Cell Tumor

Anatomical Context for Desmoplastic Small Round Cell Tumor

MalaCards organs/tissues related to Desmoplastic Small Round Cell Tumor:

39
Lung, Ovary, Bone, Lymph Node, Liver, Spleen, Small Intestine

Publications for Desmoplastic Small Round Cell Tumor

Articles related to Desmoplastic Small Round Cell Tumor:

(show top 50) (show all 282)
id Title Authors Year
1
Clinical features and outcomes of 20 patients with abdominopelvic desmoplastic small round cell tumor. ( 27890349 )
2017
2
Desmoplastic small round cell tumor: postoperative retroperitoneal mass. ( 27594960 )
2016
3
Ovarian involvement of a desmoplastic small round cell tumor of unknown primary origin with lymph node and lung metastases: A case report. ( 26893704 )
2016
4
Solid-Pattern Desmoplastic Small Round Cell Tumor. ( 27431755 )
2016
5
Sister Mary Joseph nodule caused by metastatic desmoplastic small round cell tumor: A clinicopathological report. ( 27900084 )
2016
6
Desmoplastic Small Round Cell Tumor of the Pleura Successfully Treated with a Lower Dose of Pazopanib. ( 27580551 )
2016
7
A genomic case study of desmoplastic small round cell tumor: comprehensive analysis reveals insights into potential therapeutic targets and development of a monitoring tool for a rare and aggressive disease. ( 27863505 )
2016
8
Annulate Lamellae in a Desmoplastic Small Round Cell Tumor. ( 27098589 )
2016
9
Desmoplastic Small Round Cell Tumor Presenting as an Isolated Testicular Mass in an Adult With Multiple Previous Malignancies. ( 26786560 )
2016
10
Diagnosis of desmoplastic small-round-cell tumor by cytogenetic analysis: a case report. ( 27190620 )
2016
11
Management of a rapidly enlarging new adnexal mass: a rare case of desmoplastic small round cell tumor of the ovary arising in pregnancy. ( 27354996 )
2016
12
Desmoplastic Small Round Cell Tumor of the Kidney: AIRP Best Cases in Radiologic-Pathologic Correlation. ( 27618327 )
2016
13
Birth and evolution of the desmoplastic small round-cell tumor. ( 27312937 )
2016
14
Clinical Characteristics and Outcomes of Pediatric Patients with Desmoplastic Small Round Cell Tumor. ( 27134714 )
2016
15
Complete response of giant desmoplastic small round cell tumor treated with chemoradiotherapy: A case report. ( 26893693 )
2016
16
Desmoplastic Small Round Cell Tumor: Pathology, Genetics, and Potential Therapeutic Strategies. ( 27621277 )
2016
17
Central nervous system recurrence of desmoplastic small round cell tumor following aggressive multimodal therapy: A case report. ( 26870296 )
2016
18
Management of desmoplastic small round cell tumor. ( 27955733 )
2016
19
Intracranial desmoplastic small round cell tumor presenting as a suprasellar mass. ( 25479120 )
2015
20
FDG PET/CT imaging of desmoplastic small round cell tumor: findings at staging, during treatment and at follow-up. ( 25721584 )
2015
21
Desmoplastic small round cell tumor in transverse colon: report of a rare case. ( 26011199 )
2015
22
Unusual morphology of desmoplastic small round cell tumor from an ascitic fluid in the postchemotherapy setting. ( 25948947 )
2015
23
Desmoplastic small round cell tumor of the kidney with unusual imaging features. ( 26093512 )
2015
24
Desmoplastic small round cell tumor: Diagnostic dilemma and uncertain prognosis: Report of few cases. ( 26881606 )
2015
25
Beware of immunohistochemistry--report of a cytokeratin-, desmin- and INI-1-negative pelvic desmoplastic small round cell tumor in a 51 year old woman. ( 25755805 )
2015
26
Desmoplastic Small Round Cell Tumor (DSRCT): an Unusual Intra-abdominal Tumor. ( 25829717 )
2015
27
Multimodal treatment of abdominal and pelvic desmoplastic small round cell tumor with relative good prognosis. ( 25743388 )
2015
28
Myeloablative chemotherapy with autologous stem cell transplant for desmoplastic small round cell tumor. ( 25945075 )
2015
29
Results of multimodal treatment for desmoplastic small round cell tumor of the abdomen and pelvis. ( 26309640 )
2015
30
Desmoplastic small-round-cell tumor of the abdomen: A report of two rare cases. ( 26622557 )
2015
31
Desmoplastic small round cell tumor of the lung: A case report and literature review. ( 26744673 )
2015
32
Requirement for novel surgical and clinical protocols for the treatment of desmoplastic small round cell tumor: A report of two cases and a review of the literature. ( 26622633 )
2015
33
A Case of Desmoplastic Small Round Cell Tumor. ( 26629298 )
2015
34
Primary desmoplastic small round cell tumor of the testis: First case in India and review of the literature. ( 26458624 )
2015
35
Desmoplastic Small Round Cell Tumor, a "Floating Island" Pattern in Pleural Fluid Cytology: A Case Report and Review of the Literature. ( 26413364 )
2015
36
Desmoplastic small round cell tumor: A case report of a rare differential diagnosis of solid tumors of the pleura. ( 26722277 )
2015
37
Desmoplastic small round cell tumor 20 years after its discovery. ( 25804122 )
2015
38
Survival and toxicity following sequential multimodality treatment including whole abdominopelvic radiotherapy for patients with desmoplastic small round cell tumor. ( 26527430 )
2015
39
Complete Cytoreduction and HIPEC Improves Survival in Desmoplastic Small Round Cell Tumor. ( 24046124 )
2014
40
Primary desmoplastic small round cell tumor of the duodenum. ( 24997683 )
2014
41
Abdominal Desmoplastic Small Round Cell Tumor: Multimodal Treatment Combining Chemotherapy, Surgery, and Radiotherapy is the Best Option. ( 25300608 )
2014
42
Fine-needle aspiration in desmoplastic small round cell tumor: a report of 10 new tumors in 8 patients with clinicopathological and molecular correlations with review of the literature. ( 24639098 )
2014
43
Desmoplastic small round cell tumor of the abdomen and pelvis: clinicopathological characters of 12 cases. ( 24987737 )
2014
44
Diagnostic pitfalls of differentiating desmoplastic small round cell tumor (DSRCT) from Wilms tumor (WT): overlapping morphologic and immunohistochemical features. ( 24832162 )
2014
45
Testicular desmoplastic small round cell tumor: a case report and review of literature. ( 25037705 )
2014
46
Paratesticular desmoplastic small round cell tumor with metastasis: a report of two cases. ( 24444541 )
2014
47
State of the art in oncology: high risk neuroblastoma, alveolar rhabdomyosarcoma, desmoplastic small round cell tumor, and POST-TEXT 3 and 4 hepatoblastoma. ( 24528957 )
2014
48
Paraneoplastic secondary hypertension due to a renin-secreting desmoplastic small round cell tumor: A case report. ( 25289084 )
2014
49
Desmoplastic small round cell tumor: report of 2 cases treated with chemotherapy alone or in combination with bevacizumab. ( 24707256 )
2014
50
Desmoplastic small round cell tumor with sphere-like clusters mimicking adenocarcinoma. ( 24819999 )
2014

Variations for Desmoplastic Small Round Cell Tumor

Copy number variations for Desmoplastic Small Round Cell Tumor from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 163402 22 27994016 28026515 Translate EWSR1 Desmoplastic small round cell tumor

Expression for Desmoplastic Small Round Cell Tumor

Search GEO for disease gene expression data for Desmoplastic Small Round Cell Tumor.

Pathways for Desmoplastic Small Round Cell Tumor

Pathways related to Desmoplastic Small Round Cell Tumor according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.51 EWSR1 FLI1 TSPAN7 WT1
2 11.34 S100B SYP VIM
3 11.19 ACTC1 DES VIM
4 11 ALPP DES MYOD1 MYOG PTPRC

GO Terms for Desmoplastic Small Round Cell Tumor

Biological processes related to Desmoplastic Small Round Cell Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 myotube differentiation GO:0014902 9.26 MYOD1 MYOG
2 positive regulation of skeletal muscle fiber development GO:0048743 9.16 MYOD1 MYOG
3 muscle cell fate commitment GO:0042693 8.96 MYOD1 MYOG
4 muscle filament sliding GO:0030049 8.8 ACTC1 DES VIM

Sources for Desmoplastic Small Round Cell Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
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70 UMLS via Orphanet
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