Aliases & Classifications for Desmoplastic Small Round Cell Tumor

MalaCards integrated aliases for Desmoplastic Small Round Cell Tumor:

Name: Desmoplastic Small Round Cell Tumor 49 55 69
Desmoplastic Small Round-Cell Tumor 49 51
Dsrct 49 55

Characteristics:

Orphanet epidemiological data:

55
desmoplastic small round cell tumor
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe); Age of onset: Adolescent,Adult;

Classifications:



External Ids:

Orphanet 55 ORPHA83469
MESH via Orphanet 42 D058405
UMLS via Orphanet 70 C0281508
ICD10 via Orphanet 33 C48.2
UMLS 69 C0281508

Summaries for Desmoplastic Small Round Cell Tumor

NIH Rare Diseases : 49 Desmoplastic small round celltumor (DSRCT) is a rare type of soft tissuecancer (sarcoma) that usually begins in the abdomen. It primarily affects children and young adults and is more common in males. It is formed by small, round cancer cells surrounded by scar-like tissue and is often found in the tissue (peritoneum) that lines the inside of the abdomen and pelvis. The tumor cells have a characteristic genetic change involving a translocation between chromosomes 11 and 22, which is important in differentiating from other similar tumors. The genetic change involved in DSRCT is acquired throughout a person's lifetime and is not inherited. Symptoms may include abdominal pain and a feeling of fullness, abdominal mass, and symptoms of gastrointestinal obstruction, such as constipation. Treatment options may include: chemotherapy, radiation therapy, surgery, and stem cell transplantation. Last updated: 9/9/2016

MalaCards based summary : Desmoplastic Small Round Cell Tumor, also known as desmoplastic small round-cell tumor, is related to sarcoma, synovial and rhabdomyosarcoma 2, and has symptoms including ascites, anemia and nausea and vomiting. An important gene associated with Desmoplastic Small Round Cell Tumor is EWSR1 (EWS RNA Binding Protein 1), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Doxorubicin and Vincristine have been mentioned in the context of this disorder. Affiliated tissues include lung, bone and liver, and related phenotype is respiratory system.

Wikipedia : 72 Desmoplastic small-round-cell tumor is an aggressive and rare cancer that primarily occurs as masses in... more...

Related Diseases for Desmoplastic Small Round Cell Tumor

Diseases related to Desmoplastic Small Round Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 275)
# Related Disease Score Top Affiliating Genes
1 sarcoma, synovial 31.1 DES MUC1 VIM
2 rhabdomyosarcoma 2 30.5 DES ENO2 MYOD1 MYOG WT1
3 ewing's family of tumors 30.2 CSF3 EWSR1 FLI1
4 rhabdomyosarcoma 30.1 DES ENO2 EWSR1 MYOD1 MYOG PTPRC
5 hemangiopericytoma, malignant 29.7 ACTC1 DES MUC1 S100B VIM
6 malignant peripheral nerve sheath tumor 29.6 ACTC1 MUC1 MYOG S100B VIM
7 gastrointestinal stromal tumor 28.5 ACTC1 CHGA DES ENO2 S100B SYP
8 ewing sarcoma 26.8 CD99 CHGA CSF3 DES ENO2 EWSR1
9 skin glomus tumor 10.7 DES VIM
10 infantile digital fibromatosis 10.6 DES VIM
11 lymphangiomatosis 10.6 DES VIM
12 pilomatrix carcinoma 10.6 ENO2 MUC1
13 bladder sarcoma 10.6 CD99 EWSR1
14 pediatric ovarian germ cell tumor 10.6 ALPP ENO2
15 malignant sertoli cell tumor 10.6 ENO2 SYP
16 small cell osteogenic sarcoma 10.6 ENO2 EWSR1
17 pediatric ovarian dysgerminoma 10.6 ALPP ENO2
18 malignant ectomesenchymoma 10.6 DES ENO2
19 spindle cell thymoma 10.6 DES MUC1
20 endosalpingiosis 10.6 MUC1 WT1
21 malignant peritoneal mesothelioma 10.6 MUC1 VIM
22 sarcoma 10.6
23 orbital granuloma 10.6 CSF3 MUC1
24 cutaneous ganglioneuroma 10.6 ENO2 SYP
25 sensory organ benign neoplasm 10.5 ENO2 SYP
26 epulis 10.5 DES ENO2 VIM
27 cervical polyp 10.5 DES MYOD1
28 ectomesenchymoma 10.5 DES ENO2
29 pancreatic somatostatinoma 10.5 ENO2 SYP
30 ovarian small cell carcinoma 10.5 MUC1 SYP WT1
31 kidney clear cell sarcoma 10.5 DES WT1
32 mesenchymal chondrosarcoma 10.5 DES MUC1 VIM
33 orbital cancer 10.5 ENO2 EWSR1 SYP
34 extraosseous chondrosarcoma 10.5 ENO2 EWSR1 SYP
35 extrahepatic bile duct adenocarcinoma 10.5 ENO2 SYP
36 sinonasal undifferentiated carcinoma 10.5 ENO2 MUC1 SYP
37 congenital epulis 10.5 DES ENO2 VIM
38 middle ear adenoma 10.5 ENO2 MUC1 SYP
39 lung combined type small cell carcinoma 10.5 MYOG SYP
40 chondroid chordoma 10.5 ENO2 MUC1 VIM
41 astroblastoma 10.5 ENO2 SYP VIM
42 hereditary wilms' tumor 10.5
43 localized hypertrophic neuropathy 10.5 MUC1 S100B
44 ovarian mucinous neoplasm 10.5 ENO2 SYP WT1
45 melanotic neuroectodermal tumor 10.5 ENO2 SYP VIM
46 sclerosing perineurioma 10.5 MUC1 S100B
47 hydromyelia 10.5 S100B VIM
48 testicular granulosa cell tumor 10.5 CD99 WT1
49 spindle cell rhabdomyosarcoma 10.5 DES MUC1 MYOD1
50 mucinous ovarian cystadenoma 10.5 ENO2 MUC1 SYP

Graphical network of the top 20 diseases related to Desmoplastic Small Round Cell Tumor:



Diseases related to Desmoplastic Small Round Cell Tumor

Symptoms & Phenotypes for Desmoplastic Small Round Cell Tumor

Human phenotypes related to Desmoplastic Small Round Cell Tumor:

55 31 (show all 18)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 ascites 55 31 occasional (7.5%) Occasional (29-5%) HP:0001541
2 anemia 55 31 occasional (7.5%) Occasional (29-5%) HP:0001903
3 nausea and vomiting 55 31 frequent (33%) Frequent (79-30%) HP:0002017
4 abdominal pain 55 31 hallmark (90%) Very frequent (99-80%) HP:0002027
5 hepatomegaly 55 31 frequent (33%) Frequent (79-30%) HP:0002240
6 abnormality of the peritoneum 55 31 hallmark (90%) Very frequent (99-80%) HP:0002585
7 ileus 55 31 frequent (33%) Frequent (79-30%) HP:0002595
8 neoplasm of the pancreas 55 31 occasional (7.5%) Occasional (29-5%) HP:0002894
9 abdominal distention 55 31 hallmark (90%) Very frequent (99-80%) HP:0003270
10 cachexia 55 31 occasional (7.5%) Occasional (29-5%) HP:0004326
11 testicular neoplasm 55 31 occasional (7.5%) Occasional (29-5%) HP:0010788
12 neoplasm of the central nervous system 55 31 occasional (7.5%) Occasional (29-5%) HP:0100006
13 sarcoma 55 31 hallmark (90%) Very frequent (99-80%) HP:0100242
14 neoplasm of the lung 55 31 occasional (7.5%) Occasional (29-5%) HP:0100526
15 ovarian neoplasm 55 31 occasional (7.5%) Occasional (29-5%) HP:0100615
16 mediastinal lymphadenopathy 55 31 frequent (33%) Frequent (79-30%) HP:0100721
17 weight loss 55 Frequent (79-30%)
18 lymphadenopathy 55 Very frequent (99-80%)

UMLS symptoms related to Desmoplastic Small Round Cell Tumor:


pain

MGI Mouse Phenotypes related to Desmoplastic Small Round Cell Tumor:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 respiratory system MP:0005388 9.17 ENO2 MYOD1 MYOG PTPRC THBD VIM

Drugs & Therapeutics for Desmoplastic Small Round Cell Tumor

Drugs for Desmoplastic Small Round Cell Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 107)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 2, Phase 3,Phase 1 23214-92-8 31703
2
Vincristine Approved, Investigational Phase 3,Phase 2 2068-78-2, 57-22-7 5978
3
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
4
Carboplatin Approved Phase 3,Phase 2 41575-94-4 10339178 38904 498142
5
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
6
Ifosfamide Approved Phase 3,Phase 2 3778-73-2 3690
7
Epirubicin Approved Phase 3,Phase 2 56420-45-2 41867
8
Dactinomycin Approved, Investigational Phase 3,Phase 2 50-76-0 457193 2019
9
Trabectedin Approved, Investigational Phase 2, Phase 3 114899-77-3 108150
10
Doxil Approved June 1999 Phase 2, Phase 3,Phase 1 31703
11 Isophosphamide mustard Phase 3,Phase 2 0
12 Alkylating Agents Phase 3,Phase 2,Phase 1,Early Phase 1
13 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1,Early Phase 1
14 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
15 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
16 Anti-Infective Agents Phase 3,Phase 2,Phase 1
17 Etoposide phosphate Phase 3,Phase 2
18 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
19 Antimitotic Agents Phase 3,Phase 2
20 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
21 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Early Phase 1
22 Antirheumatic Agents Phase 3,Phase 2
23
Tacrolimus Approved, Investigational Phase 2 104987-11-3 445643 439492
24
Cisplatin Approved Phase 2,Phase 1 15663-27-1 2767 441203 84093
25
Topotecan Approved, Investigational Phase 2 119413-54-6, 123948-87-8 60700
26
Melphalan Approved Phase 2,Phase 1 148-82-3 460612 4053
27
Fludarabine Approved Phase 2,Phase 1 21679-14-1, 75607-67-9 30751
28
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
29
Mechlorethamine Approved, Investigational Phase 2 51-75-2 4033
30
Everolimus Approved Phase 2 159351-69-6 6442177
31 Thiotepa Approved, Investigational Phase 2,Phase 1 52-24-4 5453
32
Lenograstim Approved, Investigational Phase 2,Phase 1 135968-09-1
33
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
34
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
35
Sirolimus Approved, Investigational Phase 2 53123-88-9 46835353 6436030 5284616
36
Arsenic trioxide Approved, Investigational Phase 2 1327-53-3 518740
37
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
38
Gemcitabine Approved Phase 2 95058-81-4 60750
39
Iodine Approved, Investigational Phase 2,Phase 1 7553-56-2 807
40
Aldesleukin Approved Phase 1, Phase 2 110942-02-4, 85898-30-2
41
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
42
Irinotecan Approved, Investigational Phase 2,Early Phase 1 97682-44-5, 100286-90-6 60838
43
Acetaminophen Approved Phase 2 103-90-2 1983
44
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
45
Diphenhydramine Approved, Investigational Phase 2 58-73-1, 147-24-0 3100
46
Temozolomide Approved, Investigational Phase 2,Early Phase 1 85622-93-1 5394
47
Promethazine Approved, Investigational Phase 2 60-87-7 4927
48
Bevacizumab Approved, Investigational Phase 2,Early Phase 1 216974-75-3
49
nivolumab Approved Phase 2 946414-94-4
50
Vitamin C Approved, Nutraceutical Phase 2 50-81-7 54670067 5785

Interventional clinical trials:

(show all 42)

# Name Status NCT ID Phase Drugs
1 Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00002898 Phase 3 carboplatin;cyclophosphamide;epirubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
2 Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma Terminated NCT01189253 Phase 2, Phase 3 doxorubicin hydrochloride;trabectedin
3 Imatinib Mesylate in Patients With Refractory Desmoplastic Small Round Cell Tumors Completed NCT00417807 Phase 1, Phase 2 Imatinib mesilate
4 QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors Completed NCT00563680 Phase 2 AMG 479
5 Imatinib Mesylate in Treating Patients With Recurrent Ewing's Family of Tumors or Desmoplastic Small Round-Cell Tumor Completed NCT00062205 Phase 2 imatinib mesylate
6 Exatecan Mesylate in Treating Patients With Ewing's Sarcoma, Primitive Neuroectodermal Tumor, or Desmoplastic Small Round Cell Tumor Completed NCT00055952 Phase 2 exatecan mesylate
7 Pilot Study of Hyperthermic Peritoneal Perfusion (HIPEC) for Adolescent and Young Adults With Desmoplastic Small Round Cell Tumor Completed NCT01277744 Phase 2 Cisplatin
8 A Study of R1507 in Participants With Recurrent or Refractory Sarcoma Completed NCT00642941 Phase 2 RG1507
9 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2 Gamma-Secretase Inhibitor RO4929097;Vismodegib
10 Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood Completed NCT00030667 Phase 2 imatinib mesylate
11 Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas Completed NCT00043979 Phase 2 F-18 Fluorodeoxyglucose;cyclophosphamide;cyclosporine;doxorubicin hydrochloride;etoposide;fludarabine phosphate;melphalan;prednisone;sirolimus;tacrolimus;vincristine sulfate;Filgrastim
12 BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors Completed NCT00526149 Phase 2 BI 2536
13 Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas Completed NCT00474994 Phase 2 sunitinib malate
14 Combination Chemotherapy and Radiation Therapy in Treating Patients With Peripheral Neuroectodermal Tumors, Ewing's Sarcoma, Wilms' Tumor, or Bone Cancer Completed NCT00002466 Phase 2 cyclophosphamide;doxorubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
15 Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors Completed NCT00025441 Phase 2 carboplatin;cyclophosphamide;doxorubicin hydrochloride;epirubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
16 Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors Completed NCT00024258 Phase 2 arsenic trioxide
17 Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer Completed NCT00002515 Phase 2 carboplatin;thiotepa;topotecan hydrochloride
18 Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma Recruiting NCT03275818 Phase 2 nab paclitaxel
19 Activated T Cells Armed With GD2 Bispecific Antibody in Children and Young Adults With Neuroblastoma and Osteosarcoma Recruiting NCT02173093 Phase 1, Phase 2
20 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma Recruiting NCT01532687 Phase 2 Gemcitabine Hydrochloride;Pazopanib Hydrochloride
21 Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors Active, not recruiting NCT01946529 Phase 2 vincristine;doxorubicin;cyclophosphamide;ifosfamide;etoposide;temozolomide;temsirolimus;bevacizumab;sorafenib
22 Therapy to Treat Ewing's Sarcoma, Rhabdomyosarcoma or Neuroblastoma Active, not recruiting NCT00923351 Phase 1, Phase 2 Tumor Purged/CD25 Depleted Lymphocytes;rhIL-7
23 Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer Active, not recruiting NCT00445965 Phase 2
24 A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma Not yet recruiting NCT02982486 Phase 2 Ipilimumab;Nivolumab
25 Study of High Dose Intravenous (IV) Ascorbic Acid in Measurable Solid Tumor Disease Suspended NCT01125449 Phase 2 Ascorbic acid (vitamin C)
26 Tanespimycin in Treating Young Patients With Recurrent or Refractory Leukemia or Solid Tumors Completed NCT00093821 Phase 1 tanespimycin
27 Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin for Children With Peritoneal Cancer Completed NCT00436657 Phase 1 CHPP of Cisplatin
28 Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma Completed NCT00720174 Phase 1 Doxorubicin Hydrochloride
29 AMG-479 in Treating Patients With Advanced Solid Tumors or Non-Hodgkin Lymphoma Completed NCT00562380 Phase 1
30 Intraperitoneal Radioimmunotherapy With 131I-8H9 for Patients With Desmoplastic Small Round Cell Tumors and Other Solid Tumors Involving the Peritoneum Recruiting NCT01099644 Phase 1
31 Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors Recruiting NCT02982941 Phase 1 Enoblituzumab
32 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer Recruiting NCT00089245 Phase 1
33 Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors Terminated NCT00003926 Phase 1 amifostine trihydrate;busulfan;filgrastim;melphalan;thiotepa
34 Studying Genes in Samples From Younger Patients With Desmoplastic Small Round Cell Tumor Registered on COG-D9902 or COG-ABTR01B1 Completed NCT01430637
35 Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas Completed NCT01567046
36 Combination Chemotherapy in Treating Patients With Sarcoma Completed NCT00662233 cyclophosphamide;doxorubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
37 Understanding Communication in Healthcare to Achieve Trust (U-CHAT) Recruiting NCT02846038
38 Irinotecan, Temozolomide and Bevacizumab in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Newly Diagnosed Patients With Desmoplastic Small Round Cell Tumor Active, not recruiting NCT01189643 Early Phase 1 irinotecan, temozolomide, and bevacizumab incorporated into an existing schedule of high dose alkylator
39 French National Registry of Rare Peritoneal Surface Malignancies Active, not recruiting NCT02834169
40 Quality of Life Study for Pediatric and Adult Patients Undergoing Hyperthermic Peritoneal Perfusion With Cisplatin Active, not recruiting NCT00502177
41 Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Active, not recruiting NCT00919269
42 Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma Withdrawn NCT00334984 glutamine

Search NIH Clinical Center for Desmoplastic Small Round Cell Tumor

Genetic Tests for Desmoplastic Small Round Cell Tumor

Anatomical Context for Desmoplastic Small Round Cell Tumor

MalaCards organs/tissues related to Desmoplastic Small Round Cell Tumor:

38
Lung, Bone, Liver, Ovary, Lymph Node, Small Intestine, Brain

Publications for Desmoplastic Small Round Cell Tumor

Articles related to Desmoplastic Small Round Cell Tumor:

(show top 50) (show all 296)
# Title Authors Year
1
Primary desmoplastic small round cell tumor in the left orbit: a case report and literature review. ( 29383463 )
2018
2
A Case Report of Abdominal Desmoplastic Small Round Cell Tumor in a Young Tunisian Woman. ( 29313236 )
2018
3
Desmoplastic Small Round Cell Tumor Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Results of a Phase 2 Trial. ( 29383611 )
2018
4
Clinical Activity of Pazopanib in Patients with Advanced Desmoplastic Small Round Cell Tumor. ( 29212731 )
2017
5
Clinical features and outcomes of 20 patients with abdominopelvic desmoplastic small round cell tumor. ( 27890349 )
2017
6
Abdominal desmoplastic small round cell tumor without extraperitoneal metastases: Is there a benefit for HIPEC after macroscopically complete cytoreductive surgery? ( 28234908 )
2017
7
Desmoplastic Small Round Cell Tumor: A Rare Case of Extraluminal Bowel Obstruction and Review of the Literature. ( 29282625 )
2017
8
Desmoplastic Small Round-Cell Tumor in a Young Indigenous Australian Man: A Case Report. ( 28717745 )
2017
9
Clinical activity of eribulin in advanced desmoplastic small round-cell tumor. ( 28863036 )
2017
10
Recurrent desmoplastic small round cell tumor responding to an mTOR inhibitor containing regimen. ( 28941151 )
2017
11
Mechanism of action of trabectedin in desmoplastic small round cell tumor cells. ( 28166781 )
2017
12
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy combined with two-stage hepatectomy for multiple and bilobar desmoplastic small round cell tumor liver metastases. ( 28890830 )
2017
13
Desmoplastic Small Round Cell Tumor Presenting as an Ocular Mass: Unusual Localization and Remarkable Surgical Approach. ( 29043531 )
2017
14
Desmoplastic small round cell tumor: evaluation of reverse transcription-polymerase chain reaction and fluorescence in situ hybridization as ancillary molecular diagnostic techniques. ( 28748349 )
2017
15
Antiangiogenic effects in patients with progressive desmoplastic small round cell tumor: data from the French national registry dedicated to the use of off-labeled targeted therapy in sarcoma (OUTC's). ( 28491276 )
2017
16
Desmoplastic small round cell tumor: postoperative retroperitoneal mass. ( 27594960 )
2016
17
Annulate Lamellae in a Desmoplastic Small Round Cell Tumor. ( 27098589 )
2016
18
Clinical Characteristics and Outcomes of Pediatric Patients with Desmoplastic Small Round Cell Tumor. ( 27134714 )
2016
19
Central nervous system recurrence of desmoplastic small round cell tumor following aggressive multimodal therapy: A case report. ( 26870296 )
2016
20
Solid-Pattern Desmoplastic Small Round Cell Tumor. ( 27431755 )
2016
21
Management of a rapidly enlarging new adnexal mass: a rare case of desmoplastic small round cell tumor of the ovary arising in pregnancy. ( 27354996 )
2016
22
Desmoplastic Small Round Cell Tumor of the Kidney: AIRP Best Cases in Radiologic-Pathologic Correlation. ( 27618327 )
2016
23
Diagnosis of desmoplastic small-round-cell tumor by cytogenetic analysis: a case report. ( 27190620 )
2016
24
Desmoplastic Small Round Cell Tumor: Pathology, Genetics, and Potential Therapeutic Strategies. ( 27621277 )
2016
25
Sister Mary Joseph nodule caused by metastatic desmoplastic small round cell tumor: A clinicopathological report. ( 27900084 )
2016
26
Desmoplastic Small Round Cell Tumor of the Pleura Successfully Treated with a Lower Dose of Pazopanib. ( 27580551 )
2016
27
Birth and evolution of the desmoplastic small round-cell tumor. ( 27312937 )
2016
28
Desmoplastic Small Round Cell Tumor Presenting as an Isolated Testicular Mass in an Adult With Multiple Previous Malignancies. ( 26786560 )
2016
29
Management of desmoplastic small round cell tumor. ( 27955733 )
2016
30
A genomic case study of desmoplastic small round cell tumor: comprehensive analysis reveals insights into potential therapeutic targets and development of a monitoring tool for a rare and aggressive disease. ( 27863505 )
2016
31
Ovarian involvement of a desmoplastic small round cell tumor of unknown primary origin with lymph node and lung metastases: A case report. ( 26893704 )
2016
32
Complete response of giant desmoplastic small round cell tumor treated with chemoradiotherapy: A case report. ( 26893693 )
2016
33
Requirement for novel surgical and clinical protocols for the treatment of desmoplastic small round cell tumor: A report of two cases and a review of the literature. ( 26622633 )
2015
34
Desmoplastic Small Round Cell Tumor, a "Floating Island" Pattern in Pleural Fluid Cytology: A Case Report and Review of the Literature. ( 26413364 )
2015
35
Primary desmoplastic small round cell tumor of the testis: First case in India and review of the literature. ( 26458624 )
2015
36
Desmoplastic small round cell tumor in transverse colon: report of a rare case. ( 26011199 )
2015
37
Myeloablative chemotherapy with autologous stem cell transplant for desmoplastic small round cell tumor. ( 25945075 )
2015
38
Desmoplastic Small Round Cell Tumor (DSRCT): an Unusual Intra-abdominal Tumor. ( 25829717 )
2015
39
Desmoplastic small round cell tumor: A case report of a rare differential diagnosis of solid tumors of the pleura. ( 26722277 )
2015
40
Survival and toxicity following sequential multimodality treatment including whole abdominopelvic radiotherapy for patients with desmoplastic small round cell tumor. ( 26527430 )
2015
41
Results of multimodal treatment for desmoplastic small round cell tumor of the abdomen and pelvis. ( 26309640 )
2015
42
Desmoplastic small round cell tumor of the kidney with unusual imaging features. ( 26093512 )
2015
43
Multimodal treatment of abdominal and pelvic desmoplastic small round cell tumor with relative good prognosis. ( 25743388 )
2015
44
Desmoplastic small round cell tumor of the lung: A case report and literature review. ( 26744673 )
2015
45
A Case of Desmoplastic Small Round Cell Tumor. ( 26629298 )
2015
46
FDG PET/CT imaging of desmoplastic small round cell tumor: findings at staging, during treatment and at follow-up. ( 25721584 )
2015
47
Desmoplastic small round cell tumor 20 years after its discovery. ( 25804122 )
2015
48
Beware of immunohistochemistry--report of a cytokeratin-, desmin- and INI-1-negative pelvic desmoplastic small round cell tumor in a 51 year old woman. ( 25755805 )
2015
49
Unusual morphology of desmoplastic small round cell tumor from an ascitic fluid in the postchemotherapy setting. ( 25948947 )
2015
50
Intracranial desmoplastic small round cell tumor presenting as a suprasellar mass. ( 25479120 )
2015

Variations for Desmoplastic Small Round Cell Tumor

Copy number variations for Desmoplastic Small Round Cell Tumor from CNVD:

7
# CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 163402 22 27994016 28026515 Translate EWSR1 Desmoplastic small round cell tumor

Expression for Desmoplastic Small Round Cell Tumor

Search GEO for disease gene expression data for Desmoplastic Small Round Cell Tumor.

Pathways for Desmoplastic Small Round Cell Tumor

Pathways related to Desmoplastic Small Round Cell Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.53 EWSR1 FLI1 TSPAN7 WT1
2 11.33 S100B SYP VIM
3 11.19 ACTC1 DES VIM
4 11 ALPP DES MYOD1 MYOG PTPRC

GO Terms for Desmoplastic Small Round Cell Tumor

Biological processes related to Desmoplastic Small Round Cell Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 myotube differentiation GO:0014902 9.26 MYOD1 MYOG
2 positive regulation of skeletal muscle fiber development GO:0048743 9.16 MYOD1 MYOG
3 muscle cell fate commitment GO:0042693 8.96 MYOD1 MYOG
4 muscle filament sliding GO:0030049 8.8 ACTC1 DES VIM

Sources for Desmoplastic Small Round Cell Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....