MCID: DTR001
MIFTS: 25

Detrusor Sphincter Dyssynergia malady

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Summaries for Detrusor Sphincter Dyssynergia

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65Wikipedia, 33MalaCards
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Wikipedia:65 Bladder sphincter dyssynergia (also known as detrusor sphincter dysynergia (DSD) (the ICS standard... more...

MalaCards: Detrusor Sphincter Dyssynergia, also known as detrusor and sphincter dyssynergia, is related to spinal cord injury and urethritis. An important gene associated with Detrusor Sphincter Dyssynergia is SLC25A19 (solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19). Affiliated tissues include spinal cord, and related mouse phenotype craniofacial.

Aliases & Classifications for Detrusor Sphincter Dyssynergia

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8Disease Ontology, 10DISEASES, 62UMLS, 27ICD9CM, 58SNOMED-CT
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Aliases & Descriptions:

detrusor sphincter dyssynergia 8 10
detrusor and sphincter dyssynergia 8 62


External Ids:

Disease Ontology8 DOID:12145
SNOMED-CT58 236655005
ICD9CM27 596.55

Related Diseases for Detrusor Sphincter Dyssynergia

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17GeneCards, 18GeneDecks
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Diseases related to Detrusor Sphincter Dyssynergia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1spinal cord injury11.0
2urethritis10.9
3blindness10.6
4spinal cord disease10.6
5hydronephrosis10.4
6herpes simplex10.4
7multiple sclerosis10.4
8multiple system atrophy10.4
9spina bifida10.4
10hinman syndrome10.4
11microcephaly10.0SLC25A19, CASK

Graphical network of diseases related to Detrusor Sphincter Dyssynergia:



Diseases related to detrusor sphincter dyssynergia

Symptoms for Detrusor Sphincter Dyssynergia

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Drugs & Therapeutics for Detrusor Sphincter Dyssynergia

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Genetic Tests for Detrusor Sphincter Dyssynergia

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Anatomical Context for Detrusor Sphincter Dyssynergia

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33MalaCards
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MalaCards organs/tissues related to Detrusor Sphincter Dyssynergia:

33
Spinal cord

Animal Models for Detrusor Sphincter Dyssynergia or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Detrusor Sphincter Dyssynergia:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.0SLC25A19, CASK

Publications for Detrusor Sphincter Dyssynergia

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52PubMed
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Articles related to Detrusor Sphincter Dyssynergia:

(show top 50)    (show all 72)
idTitleAuthorsYear
1
Long-term outcome of intravesical oxybutynin in children with detrusor-sphincter dyssynergia: With special reference to age-dependent parameters. (24436114)
2014
2
Therapeutic outcome and quality of life between urethral and detrusor botulinum toxin treatment for patients with spinal cord lesions and detrusor sphincter dyssynergia. (24073977)
2013
3
Diagnosing detrusor sphincter dyssynergia in the neurological patient. (22458490)
2012
4
Therapeutic effects of detrusor botulinum toxin A injection on neurogenic detrusor overactivity in patients with different levels of spinal cord injury and types of detrusor sphincter dyssynergia. (21243000)
2011
5
Urodynamic analysis in multiple system atrophy: characterisation of detrusor-sphincter dyssynergia. (20683607)
2010
6
Transperineal injection of botulinum toxin A for treatment of detrusor sphincter dyssynergia: localization with combined fluoroscopic and electromyographic guidance. (19406304)
2009
7
Outcome after treatment of detrusor-sphincter dyssynergia by temporary stent. (17471293)
2008
8
Satisfaction with urethral injection of botulinum toxin A for detrusor sphincter dyssynergia in patients with spinal cord lesion. (18508331)
2008
9
Therapeutic satisfaction and dissatisfaction in patients with spinal cord lesions and detrusor sphincter dyssynergia who received detrusor botulinum toxin a injection. (18533231)
2008
10
Long-term follow-up study of intraurethral stents in spinal cord injured patients with detrusor-sphincter dyssynergia. (17211463)
2007
11
Treatment of detrusor sphincter dyssynergia with baclofen and doxazosin. (17124622)
2006
12
Can neurologic examination predict type of detrusor sphincter-dyssynergia in patients with spinal cord injury? (15708030)
2005
13
Urethral stents for detrusor sphincter dyssynergia. (15679792)
2005
14
Oral nitric oxide donors: a new pharmacological approach to detrusor-sphincter dyssynergia in spinal cord injured patients? (15041118)
2004
15
Sphincterotomy and the treatment of detrusor-sphincter dyssynergia: current status, future prospects. (12494314)
2003
16
Treatment of detrusor-sphincter dyssynergia by pudendal nerve block in patients with spinal cord injury. (11994813)
2002
17
Botulinum a toxin and detrusor sphincter dyssynergia: a double-blind lidocaine-controlled study in 13 patients with spinal cord disease. (12121731)
2002
18
A modified biofeedback program for children with detrusor-sphincter dyssynergia: 5-year experience. (11547115)
2001
19
Removal of UroLume endoprosthesis: experience of the North American Study Group for detrusor-sphincter dyssynergia application. (10687974)
2000
20
Biofeedback successfully cures detrusor-sphincter dyssynergia in pediatric patients. (10799231)
2000
21
Clinical significance of detrusor sphincter dyssynergia type in patients with post-traumatic spinal cord injury. (11018603)
2000
22
Long-term followup of the North American multicenter UroLume trial for the treatment of external detrusor-sphincter dyssynergia. (10210393)
1999
23
Treatment of detrusor sphincter dyssynergia by transperineal injection of botulinum toxin. (9630155)
1998
24
Bladder leak point pressure: the measure for sphincterotomy success in spinal cord injured patients with external detrusor-sphincter dyssynergia. (9649270)
1998
25
Use of the Memokath for detrusor-sphincter dyssynergia after spinal cord injury--a cautionary tale. (9471137)
1998
26
Botulinum A toxin as a treatment of detrusor-sphincter dyssynergia in patients with spinal cord injury: MRI controlled transperineal injections. (9343126)
1997
27
Detrusor-sphincter dyssynergia induced by cold stimulation of the urinary bladder of rats. (9140030)
1997
28
Balloon dilatation of the external urethral sphincter in the treatment of detrusor-sphincter dyssynergia. (9044516)
1997
29
Use of Memokath temporary urethral stent in treatment of detrusor-sphincter dyssynergia. (9440862)
1997
30
Detrusor-sphincter dyssynergia. (8711868)
1996
31
Long-term outcome of permanent urethral stents in the treatment of detrusor-sphincter dyssynergia. (8976768)
1996
32
Botulinum-A toxin as a treatment of detrusor-sphincter dyssynergia: a prospective study in 24 spinal cord injury patients. (8583552)
1996
33
Contact neodymium:yttrium-aluminum-garnet laser ablation of the external sphincter in spinal cord injured men with detrusor sphincter dyssynergia. (7771003)
1995
34
Wallstents in patients with detrusor-sphincter dyssynergia. (7609116)
1995
35
Urolume urethral wallstent in the treatment of detrusor sphincter dyssynergia. (7997341)
1994
36
Reduction of detrusor-sphincter dyssynergia during ventral sacral root stimulation: anatomical and electrophysiological experiments. (7719296)
1994
37
Endourethral prosthesis for treatment of detrusor sphincter dyssynergia: impact on quality of life for persons with spinal cord injury. (7777845)
1994
38
Permanent urethral stents for detrusor sphincter dyssynergia. (2021818)
1991
39
Treatment of detrusor-sphincter dyssynergia with botulinum A toxin: a double-blind study. (2297305)
1990
40
Combined transrectal ultrasonography and urodynamics in the evaluation of detrusor-sphincter dyssynergia. (3056566)
1988
41
Neuropeptide Y- and vasoactive intestinal polypeptide-containing nerves in the intrinsic external urethral sphincter in the areflexic bladder compared to detrusor-sphincter dyssynergia in patients with spinal cord injury. (3656550)
1987
42
Vesico-ureteral reflux in children with spina bifida and detrusor-sphincter dyssynergia. (6744873)
1984
43
Neurologic aspects of detrusor-sphincter dyssynergia, with reference to the guarding reflex. (7086999)
1982
44
Idiopathic detrusor sphincter dyssynergia in neurologically normal patients with voiding abnormalities. (7060614)
1982
45
Biomechanical basis for recommendation of transurethral sphincterotomy in spinal-cord-injury patients with detrusor-sphincter dyssynergia. (7278408)
1981
46
Baclofen in the treatment of detrusor-sphincter dyssynergia in spinal cord injury patients. (7411729)
1980
47
Pressor response during cystomanometry in spinal injury patients complicated with detrusor-sphincter dyssynergia. (37349)
1979
48
Detrusor-sphincter dyssynergia. (458950)
1979
49
A treatment of detrusor-sphincter dyssynergia: pudendal nerve block by phenolglycerin under the guide of direct nerve stimulation. (494454)
1979
50
Effect of baclofen and dantrolene on bladder stimulator-induced detrusor-sphincter dyssynergia in dogs. (566976)
1978

Variations for Detrusor Sphincter Dyssynergia

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Expression for genes affiliated with Detrusor Sphincter Dyssynergia

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Detrusor Sphincter Dyssynergia

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Pathways for genes affiliated with Detrusor Sphincter Dyssynergia

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Compounds for genes affiliated with Detrusor Sphincter Dyssynergia

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GO Terms for genes affiliated with Detrusor Sphincter Dyssynergia

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16Gene Ontology
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Cellular components related to Detrusor Sphincter Dyssynergia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1basement membraneGO:0056049.1EGFL6, CASK

Biological processes related to Detrusor Sphincter Dyssynergia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell adhesionGO:0071559.1EGFL6, CASK
2extracellular matrix organizationGO:0301988.8EGFL6, CASK

Products for genes affiliated with Detrusor Sphincter Dyssynergia

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Sources for Detrusor Sphincter Dyssynergia

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet