MCID: DTR001
MIFTS: 24

Detrusor Sphincter Dyssynergia malady

Summaries for Detrusor Sphincter Dyssynergia

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63Wikipedia, 32MalaCards
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Wikipedia:63 Bladder sphincter dyssynergia (also known as detrusor sphincter dysynergia (DSD) (the ICS standard... more...

MalaCards: Detrusor Sphincter Dyssynergia, also known as detrusor and sphincter dyssynergia, is related to urethritis and spinal cord disease. An important gene associated with Detrusor Sphincter Dyssynergia is SLC25A19 (solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19). Affiliated tissues include spinal cord.

Aliases & Classifications for Detrusor Sphincter Dyssynergia

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 27ICD9CM, 56SNOMED-CT
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Aliases & Descriptions:

detrusor sphincter dyssynergia 8 10
detrusor and sphincter dyssynergia 8 60


External Ids:

Disease Ontology8 DOID:12145
SNOMED-CT56 236655005
ICD9CM27 596.55

Related Diseases for Detrusor Sphincter Dyssynergia

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17GeneCards, 18GeneDecks
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Diseases related to Detrusor Sphincter Dyssynergia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1urethritis10.9
2spinal cord disease10.5
3hydronephrosis10.4
4herpes simplex10.4
5multiple sclerosis10.4
6multiple system atrophy10.4
7spina bifida10.4
8microcephaly10.0SLC25A19, CASK

Graphical network of diseases related to Detrusor Sphincter Dyssynergia:



Diseases related to detrusor sphincter dyssynergia

Clinical Features for Detrusor Sphincter Dyssynergia

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Drugs & Therapeutics for Detrusor Sphincter Dyssynergia

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Detrusor Sphincter Dyssynergia

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Anatomical Context for Detrusor Sphincter Dyssynergia

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32MalaCards
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MalaCards organs/tissues related to Detrusor Sphincter Dyssynergia:

32
Spinal cord

Animal Models for Detrusor Sphincter Dyssynergia or affiliated genes

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Publications for Detrusor Sphincter Dyssynergia

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50PubMed
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Articles related to Detrusor Sphincter Dyssynergia:

(show top 50)    (show all 74)
idTitleAuthorsYear
1
Long-term outcome of intravesical oxybutynin in children with detrusor-sphincter dyssynergia: With special reference to age-dependent parameters. (24436114)
2014
2
Therapeutic outcome and quality of life between urethral and detrusor botulinum toxin treatment for patients with spinal cord lesions and detrusor sphincter dyssynergia. (24073977)
2013
3
Management of detrusor external sphincter dyssynergia in neurogenic bladder. (22081065)
2011
4
Therapeutic effects of detrusor botulinum toxin A injection on neurogenic detrusor overactivity in patients with different levels of spinal cord injury and types of detrusor sphincter dyssynergia. (21243000)
2011
5
Urodynamic analysis in multiple system atrophy: characterisation of detrusor-sphincter dyssynergia. (20683607)
2010
6
Suppression of detrusor-sphincter dyssynergia by herpes simplex virus vector mediated gene delivery of glutamic acid decarboxylase in spinal cord injured rats. (20663524)
2010
7
Transperineal injection of botulinum toxin A for treatment of detrusor sphincter dyssynergia: localization with combined fluoroscopic and electromyographic guidance. (19406304)
2009
8
Outcome after treatment of detrusor-sphincter dyssynergia by temporary stent. (17471293)
2008
9
Urodynamic responses to anal stretch in patients with detrusor sphincter dyssynergia. (18760159)
2008
10
Therapeutic satisfaction and dissatisfaction in patients with spinal cord lesions and detrusor sphincter dyssynergia who received detrusor botulinum toxin a injection. (18533231)
2008
11
Long-term follow-up study of intraurethral stents in spinal cord injured patients with detrusor-sphincter dyssynergia. (17211463)
2007
12
Memokath stents for the treatment of detrusor sphincter dyssynergia (DSD) in men with spinal cord injury: the Princess Royal Spinal Injuries Unit 10-year experience. (16520816)
2007
13
Treatment of detrusor sphincter dyssynergia with baclofen and doxazosin. (17124622)
2006
14
Memokath stents for the treatment of detrusor sphincter dyssynergia (DSD) in men with spinal cord injury: the Princess Royal Spinal Injuries Unit 10-year experience. (16044169)
2006
15
Detrusor-sphincter dyssynergia. (17169006)
2006
16
Can neurologic examination predict type of detrusor sphincter-dyssynergia in patients with spinal cord injury? (15708030)
2005
17
Urethral stents for detrusor sphincter dyssynergia. (15679792)
2005
18
Placebo controlled, randomised, double blind study of the effects of botulinum A toxin on detrusor sphincter dyssynergia in multiple sclerosis patients. (16291892)
2005
19
Oral nitric oxide donors: a new pharmacological approach to detrusor-sphincter dyssynergia in spinal cord injured patients? (15041118)
2004
20
Sphincterotomy and the treatment of detrusor-sphincter dyssynergia: current status, future prospects. (12494314)
2003
21
The use of the Memokath stent in the treatment of detrusor sphincter dyssynergia in spinal cord injury patients: a single-centre seven-year experience. (12706000)
2003
22
Removal of UroLume endoprosthesis: experience of the North American Study Group for detrusor-sphincter dyssynergia application. (10687974)
2000
23
Biofeedback successfully cures detrusor-sphincter dyssynergia in pediatric patients. (10799231)
2000
24
Clinical significance of detrusor sphincter dyssynergia type in patients with post-traumatic spinal cord injury. (11018603)
2000
25
Long-term followup of the North American multicenter UroLume trial for the treatment of external detrusor-sphincter dyssynergia. (10210393)
1999
26
Treatment of detrusor sphincter dyssynergia by transperineal injection of botulinum toxin. (9630155)
1998
27
Bladder leak point pressure: the measure for sphincterotomy success in spinal cord injured patients with external detrusor-sphincter dyssynergia. (9649270)
1998
28
Pediatric case of the day. Hinman syndrome (nonneurogenic bladder [NNNB], detrusor-sphincter dyssynergia). (9460133)
1998
29
Detrusor-sphincter dyssynergia and vesico urethral reflux: management. (9471129)
1998
30
Botulinum A toxin treatment for detrusor-sphincter dyssynergia in spinal cord disease. (9494997)
1998
31
Botulinum A toxin as a treatment of detrusor-sphincter dyssynergia in patients with spinal cord injury: MRI controlled transperineal injections. (9343126)
1997
32
Detrusor-sphincter dyssynergia induced by cold stimulation of the urinary bladder of rats. (9140030)
1997
33
Balloon dilatation of the external urethral sphincter in the treatment of detrusor-sphincter dyssynergia. (9044516)
1997
34
Use of Memokath temporary urethral stent in treatment of detrusor-sphincter dyssynergia. (9440862)
1997
35
Autonomic dysreflexia and detrusor-sphincter dyssynergia in spinal cord injury patients. (9261785)
1997
36
Long-term outcome of permanent urethral stents in the treatment of detrusor-sphincter dyssynergia. (8976768)
1996
37
Wallstents in patients with detrusor-sphincter dyssynergia. (7609116)
1995
38
Permanent urethral stents for detrusor sphincter dyssynergia. (2021818)
1991
39
Detrusor sphincter dyssynergia syndrome. A new syndrome and its treatment by external sphincter myotomy. (2265659)
1990
40
Combined transrectal ultrasonography and urodynamics in the evaluation of detrusor-sphincter dyssynergia. (3056566)
1988
41
Neuropeptide Y- and vasoactive intestinal polypeptide-containing nerves in the intrinsic external urethral sphincter in the areflexic bladder compared to detrusor-sphincter dyssynergia in patients with spinal cord injury. (3656550)
1987
42
Vesico-ureteral reflux in children with spina bifida and detrusor-sphincter dyssynergia. (6744873)
1984
43
Urodynamic studies in evaluating detrusor sphincter dyssynergia and their effects on the treatment. (6540434)
1984
44
Baclofen in the treatment of detrusor-sphincter dyssynergia in spinal cord injury patients. (7411729)
1980
45
Pressor response during cystomanometry in spinal injury patients complicated with detrusor-sphincter dyssynergia. (37349)
1979
46
Detrusor-sphincter dyssynergia. (458950)
1979
47
Effect of baclofen and dantrolene on bladder stimulator-induced detrusor-sphincter dyssynergia in dogs. (566976)
1978
48
Detrusor-sphincter dyssynergia and detrusor hyperreflexia leading to hydronephrosis during intermittent catheterization. (712909)
1978
49
Anal sphincter stretch: a technique to overcome detrusor-sphincter dyssynergia. (880007)
1977
50
The syndrome of detrusor-sphincter dyssynergia. (1053342)
1976

Genetic Variations for Detrusor Sphincter Dyssynergia

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Expression for genes affiliated with Detrusor Sphincter Dyssynergia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Detrusor Sphincter Dyssynergia

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Pathways for genes affiliated with Detrusor Sphincter Dyssynergia

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Compounds for genes affiliated with Detrusor Sphincter Dyssynergia

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GO Terms for genes affiliated with Detrusor Sphincter Dyssynergia

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16Gene Ontology
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Cellular components related to Detrusor Sphincter Dyssynergia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1basement membraneGO:0056049.1EGFL6, CASK

Biological processes related to Detrusor Sphincter Dyssynergia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell adhesionGO:0071559.1EGFL6, CASK
2extracellular matrix organizationGO:0301988.8EGFL6, CASK

Products for genes affiliated with Detrusor Sphincter Dyssynergia

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Sources for Detrusor Sphincter Dyssynergia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet