MCID: DTR001
MIFTS: 24

Detrusor Sphincter Dyssynergia malady

Summaries for Detrusor Sphincter Dyssynergia

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Bladder sphincter dyssynergia (also known as detrusor sphincter dysynergia (DSD) (the ICS standard... more...

MalaCards: Detrusor Sphincter Dyssynergia, also known as detrusor and sphincter dyssynergia, is related to spinal cord injury and spinal cord disease. An important gene associated with Detrusor Sphincter Dyssynergia is SLC25A19 (solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19). Affiliated tissues include spinal cord.

Aliases & Classifications for Detrusor Sphincter Dyssynergia

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 27ICD9CM, 57SNOMED-CT
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Aliases & Descriptions:

detrusor sphincter dyssynergia 8 10
detrusor and sphincter dyssynergia 8 61


External Ids:

Disease Ontology8 DOID:12145
SNOMED-CT57 236655005
ICD9CM27 596.55

Related Diseases for Detrusor Sphincter Dyssynergia

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Detrusor Sphincter Dyssynergia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1spinal cord injury11.0
2spinal cord disease10.5
3hydronephrosis10.4
4n syndrome10.4
5spina bifida10.4
6hinman's syndrome10.4
7microcephaly10.0SLC25A19, CASK

Graphical network of diseases related to Detrusor Sphincter Dyssynergia:



Diseases related to detrusor sphincter dyssynergia

Clinical Features for Detrusor Sphincter Dyssynergia

Drugs & Therapeutics for Detrusor Sphincter Dyssynergia

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Detrusor Sphincter Dyssynergia

Anatomical Context for Detrusor Sphincter Dyssynergia

Sources:
33MalaCards
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MalaCards organs/tissues related to Detrusor Sphincter Dyssynergia:

33
Spinal cord

Animal Models for Detrusor Sphincter Dyssynergia or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Detrusor Sphincter Dyssynergia

Sources:
51PubMed
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Articles related to Detrusor Sphincter Dyssynergia:

(show top 50)    (show all 74)
idTitleAuthorsYear
1
Therapeutic outcome and quality of life between urethral and detrusor botulinum toxin treatment for patients with spinal cord lesions and detrusor sphincter dyssynergia. (24073977)
2013
2
Diagnosing detrusor sphincter dyssynergia in the neurological patient. (22458490)
2012
3
Management of detrusor external sphincter dyssynergia in neurogenic bladder. (22081065)
2011
4
Urodynamic analysis in multiple system atrophy: characterisation of detrusor-sphincter dyssynergia. (20683607)
2010
5
Olfactory mucosal transplantation after spinal cord injury improves voiding efficiency by suppressing detrusor-sphincter dyssynergia in rats. (20639055)
2010
6
Suppression of detrusor-sphincter dyssynergia by herpes simplex virus vector mediated gene delivery of glutamic acid decarboxylase in spinal cord injured rats. (20663524)
2010
7
Urodynamic responses to anal stretch in patients with detrusor sphincter dyssynergia. (18760159)
2008
8
Satisfaction with urethral injection of botulinum toxin A for detrusor sphincter dyssynergia in patients with spinal cord lesion. (18508331)
2008
9
Memokath stents for the treatment of detrusor sphincter dyssynergia (DSD) in men with spinal cord injury: the Princess Royal Spinal Injuries Unit 10-year experience. (16520816)
2007
10
Urethral stents for detrusor sphincter dyssynergia. (15679792)
2005
11
Placebo controlled, randomised, double blind study of the effects of botulinum A toxin on detrusor sphincter dyssynergia in multiple sclerosis patients. (16291892)
2005
12
Understanding detrusor sphincter dyssynergia--significance of chronology. (16230135)
2005
13
Oral nitric oxide donors: a new pharmacological approach to detrusor-sphincter dyssynergia in spinal cord injured patients? (15041118)
2004
14
Urethral stent for the treatment of detrusor-sphincter dyssynergia: evaluation of the clinical, urodynamic, endoscopic and radiological efficacy after more than 1 year. (15247742)
2004
15
Suppression of detrusor-sphincter dyssynergia by immunoneutralization of nerve growth factor in lumbosacral spinal cord in spinal cord injured rats. (14665959)
2004
16
Treatment of detrusor-sphincter dyssynergia by pudendal nerve block in patients with spinal cord injury. (11994813)
2002
17
Botulinum a toxin and detrusor sphincter dyssynergia: a double-blind lidocaine-controlled study in 13 patients with spinal cord disease. (12121731)
2002
18
A modified biofeedback program for children with detrusor-sphincter dyssynergia: 5-year experience. (11547115)
2001
19
Clinical significance of detrusor sphincter dyssynergia type in patients with post-traumatic spinal cord injury. (11018603)
2000
20
Long-term followup of the North American multicenter UroLume trial for the treatment of external detrusor-sphincter dyssynergia. (10210393)
1999
21
Bladder leak point pressure: the measure for sphincterotomy success in spinal cord injured patients with external detrusor-sphincter dyssynergia. (9649270)
1998
22
Use of the Memokath for detrusor-sphincter dyssynergia after spinal cord injury--a cautionary tale. (9471137)
1998
23
Pediatric case of the day. Hinman syndrome (nonneurogenic bladder [NNNB], detrusor-sphincter dyssynergia). (9460133)
1998
24
Detrusor-sphincter dyssynergia and vesico urethral reflux: management. (9471129)
1998
25
Botulinum A toxin treatment for detrusor-sphincter dyssynergia in spinal cord disease. (9494997)
1998
26
Botulinum A toxin as a treatment of detrusor-sphincter dyssynergia in patients with spinal cord injury: MRI controlled transperineal injections. (9343126)
1997
27
Balloon dilatation of the external urethral sphincter in the treatment of detrusor-sphincter dyssynergia. (9044516)
1997
28
Autonomic dysreflexia and detrusor-sphincter dyssynergia in spinal cord injury patients. (9261785)
1997
29
Detrusor-sphincter dyssynergia. (8711868)
1996
30
Long-term outcome of permanent urethral stents in the treatment of detrusor-sphincter dyssynergia. (8976768)
1996
31
Botulinum-A toxin as a treatment of detrusor-sphincter dyssynergia: a prospective study in 24 spinal cord injury patients. (8583552)
1996
32
Contact neodymium:yttrium-aluminum-garnet laser ablation of the external sphincter in spinal cord injured men with detrusor sphincter dyssynergia. (7771003)
1995
33
Wallstents in patients with detrusor-sphincter dyssynergia. (7609116)
1995
34
Urolume urethral wallstent in the treatment of detrusor sphincter dyssynergia. (7997341)
1994
35
Reduction of detrusor-sphincter dyssynergia during ventral sacral root stimulation: anatomical and electrophysiological experiments. (7719296)
1994
36
Endourethral prosthesis for treatment of detrusor sphincter dyssynergia: impact on quality of life for persons with spinal cord injury. (7777845)
1994
37
Treatment of detrusor-sphincter dyssynergia with botulinum A toxin: a double-blind study. (2297305)
1990
38
Combined transrectal ultrasonography and urodynamics in the evaluation of detrusor-sphincter dyssynergia. (3056566)
1988
39
Effects of botulinum A toxin on detrusor-sphincter dyssynergia in spinal cord injury patients. (3361663)
1988
40
Neuropeptide Y- and vasoactive intestinal polypeptide-containing nerves in the intrinsic external urethral sphincter in the areflexic bladder compared to detrusor-sphincter dyssynergia in patients with spinal cord injury. (3656550)
1987
41
Neurologic aspects of detrusor-sphincter dyssynergia, with reference to the guarding reflex. (7086999)
1982
42
Idiopathic detrusor sphincter dyssynergia in neurologically normal patients with voiding abnormalities. (7060614)
1982
43
Treatment of detrusor-sphincter dyssynergia by bio-feedback. (7135674)
1982
44
Biomechanical basis for recommendation of transurethral sphincterotomy in spinal-cord-injury patients with detrusor-sphincter dyssynergia. (7278408)
1981
45
Baclofen in the treatment of detrusor-sphincter dyssynergia in spinal cord injury patients. (7411729)
1980
46
Detrusor-sphincter dyssynergia. (458950)
1979
47
A treatment of detrusor-sphincter dyssynergia: pudendal nerve block by phenolglycerin under the guide of direct nerve stimulation. (494454)
1979
48
Detrusor-sphincter dyssynergia and dyssynergic responses: recognition and rationale for early modified transurethral sphincterotomy in complete spinal cord injury lesions. (702671)
1978
49
Detrusor-sphincter dyssynergia and detrusor hyperreflexia leading to hydronephrosis during intermittent catheterization. (712909)
1978
50
Anal sphincter stretch: a technique to overcome detrusor-sphincter dyssynergia. (880007)
1977

Genetic Variations for Detrusor Sphincter Dyssynergia

Expression for genes affiliated with Detrusor Sphincter Dyssynergia

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Detrusor Sphincter Dyssynergia

Search GEO for disease gene expression data for Detrusor Sphincter Dyssynergia.

Pathways for genes affiliated with Detrusor Sphincter Dyssynergia

Compounds for genes affiliated with Detrusor Sphincter Dyssynergia

GO Terms for genes affiliated with Detrusor Sphincter Dyssynergia

Sources:
16Gene Ontology
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Cellular components related to Detrusor Sphincter Dyssynergia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1basement membraneGO:0056049.1EGFL6, CASK

Biological processes related to Detrusor Sphincter Dyssynergia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell adhesionGO:0071559.1EGFL6, CASK
2extracellular matrix organizationGO:0301988.8EGFL6, CASK

Products for genes affiliated with Detrusor Sphincter Dyssynergia

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Sources for Detrusor Sphincter Dyssynergia

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet