MCID: DTR001
MIFTS: 24

Detrusor Sphincter Dyssynergia malady

Summaries for Detrusor Sphincter Dyssynergia

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63Wikipedia, 32MalaCards
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Wikipedia:63 Bladder sphincter dyssynergia (also known as detrusor sphincter dysynergia (DSD) (the ICS standard... more...

MalaCards: Detrusor Sphincter Dyssynergia, also known as detrusor and sphincter dyssynergia, is related to urethritis and spinal cord disease. An important gene associated with Detrusor Sphincter Dyssynergia is SLC25A19 (solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19). Affiliated tissues include spinal cord.

Aliases & Classifications for Detrusor Sphincter Dyssynergia

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 27ICD9CM, 56SNOMED-CT
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Aliases & Descriptions:

detrusor sphincter dyssynergia 8 10
detrusor and sphincter dyssynergia 8 60


External Ids:

Disease Ontology8 DOID:12145
SNOMED-CT56 236655005
ICD9CM27 596.55

Related Diseases for Detrusor Sphincter Dyssynergia

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17GeneCards, 18GeneDecks
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Diseases related to Detrusor Sphincter Dyssynergia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1urethritis10.9
2spinal cord disease10.5
3hydronephrosis10.4
4herpes simplex10.4
5multiple sclerosis10.4
6multiple system atrophy10.4
7spina bifida10.4
8microcephaly10.0SLC25A19, CASK

Graphical network of diseases related to Detrusor Sphincter Dyssynergia:



Diseases related to detrusor sphincter dyssynergia

Clinical Features for Detrusor Sphincter Dyssynergia

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Drugs & Therapeutics for Detrusor Sphincter Dyssynergia

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Detrusor Sphincter Dyssynergia

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Anatomical Context for Detrusor Sphincter Dyssynergia

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32MalaCards
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MalaCards organs/tissues related to Detrusor Sphincter Dyssynergia:

32
Spinal cord

Animal Models for Detrusor Sphincter Dyssynergia or affiliated genes

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Publications for Detrusor Sphincter Dyssynergia

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50PubMed
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Articles related to Detrusor Sphincter Dyssynergia:

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idTitleAuthorsYear
1
Long-term outcome of intravesical oxybutynin in children with detrusor-sphincter dyssynergia: With special reference to age-dependent parameters. (24436114)
2014
2
Therapeutic outcome and quality of life between urethral and detrusor botulinum toxin treatment for patients with spinal cord lesions and detrusor sphincter dyssynergia. (24073977)
2013
3
Diagnosing detrusor sphincter dyssynergia in the neurological patient. (22458490)
2012
4
Management of detrusor external sphincter dyssynergia in neurogenic bladder. (22081065)
2011
5
Therapeutic effects of detrusor botulinum toxin A injection on neurogenic detrusor overactivity in patients with different levels of spinal cord injury and types of detrusor sphincter dyssynergia. (21243000)
2011
6
Urodynamic analysis in multiple system atrophy: characterisation of detrusor-sphincter dyssynergia. (20683607)
2010
7
Olfactory mucosal transplantation after spinal cord injury improves voiding efficiency by suppressing detrusor-sphincter dyssynergia in rats. (20639055)
2010
8
Transperineal injection of botulinum toxin A for treatment of detrusor sphincter dyssynergia: localization with combined fluoroscopic and electromyographic guidance. (19406304)
2009
9
Outcome after treatment of detrusor-sphincter dyssynergia by temporary stent. (17471293)
2008
10
Therapeutic satisfaction and dissatisfaction in patients with spinal cord lesions and detrusor sphincter dyssynergia who received detrusor botulinum toxin a injection. (18533231)
2008
11
Long-term follow-up study of intraurethral stents in spinal cord injured patients with detrusor-sphincter dyssynergia. (17211463)
2007
12
Memokath stents for the treatment of detrusor sphincter dyssynergia (DSD) in men with spinal cord injury: the Princess Royal Spinal Injuries Unit 10-year experience. (16520816)
2007
13
Treatment of detrusor sphincter dyssynergia with baclofen and doxazosin. (17124622)
2006
14
Memokath stents for the treatment of detrusor sphincter dyssynergia (DSD) in men with spinal cord injury: the Princess Royal Spinal Injuries Unit 10-year experience. (16044169)
2006
15
Detrusor-sphincter dyssynergia. (17169006)
2006
16
Can neurologic examination predict type of detrusor sphincter-dyssynergia in patients with spinal cord injury? (15708030)
2005
17
Placebo controlled, randomised, double blind study of the effects of botulinum A toxin on detrusor sphincter dyssynergia in multiple sclerosis patients. (16291892)
2005
18
Understanding detrusor sphincter dyssynergia--significance of chronology. (16230135)
2005
19
Sphincterotomy and the treatment of detrusor-sphincter dyssynergia: current status, future prospects. (12494314)
2003
20
The use of the Memokath stent in the treatment of detrusor sphincter dyssynergia in spinal cord injury patients: a single-centre seven-year experience. (12706000)
2003
21
Treatment of detrusor-sphincter dyssynergia by pudendal nerve block in patients with spinal cord injury. (11994813)
2002
22
Botulinum a toxin and detrusor sphincter dyssynergia: a double-blind lidocaine-controlled study in 13 patients with spinal cord disease. (12121731)
2002
23
A modified biofeedback program for children with detrusor-sphincter dyssynergia: 5-year experience. (11547115)
2001
24
Removal of UroLume endoprosthesis: experience of the North American Study Group for detrusor-sphincter dyssynergia application. (10687974)
2000
25
Biofeedback successfully cures detrusor-sphincter dyssynergia in pediatric patients. (10799231)
2000
26
Treatment of detrusor sphincter dyssynergia by transperineal injection of botulinum toxin. (9630155)
1998
27
Use of the Memokath for detrusor-sphincter dyssynergia after spinal cord injury--a cautionary tale. (9471137)
1998
28
Detrusor-sphincter dyssynergia induced by cold stimulation of the urinary bladder of rats. (9140030)
1997
29
Balloon dilatation of the external urethral sphincter in the treatment of detrusor-sphincter dyssynergia. (9044516)
1997
30
Use of Memokath temporary urethral stent in treatment of detrusor-sphincter dyssynergia. (9440862)
1997
31
Long-term outcome of permanent urethral stents in the treatment of detrusor-sphincter dyssynergia. (8976768)
1996
32
Contact neodymium:yttrium-aluminum-garnet laser ablation of the external sphincter in spinal cord injured men with detrusor sphincter dyssynergia. (7771003)
1995
33
Wallstents in patients with detrusor-sphincter dyssynergia. (7609116)
1995
34
Urolume urethral wallstent in the treatment of detrusor sphincter dyssynergia. (7997341)
1994
35
Reduction of detrusor-sphincter dyssynergia during ventral sacral root stimulation: anatomical and electrophysiological experiments. (7719296)
1994
36
Endourethral prosthesis for treatment of detrusor sphincter dyssynergia: impact on quality of life for persons with spinal cord injury. (7777845)
1994
37
Permanent urethral stents for detrusor sphincter dyssynergia. (2021818)
1991
38
Detrusor sphincter dyssynergia syndrome. A new syndrome and its treatment by external sphincter myotomy. (2265659)
1990
39
Effects of botulinum A toxin on detrusor-sphincter dyssynergia in spinal cord injury patients. (3361663)
1988
40
Neuropeptide Y- and vasoactive intestinal polypeptide-containing nerves in the intrinsic external urethral sphincter in the areflexic bladder compared to detrusor-sphincter dyssynergia in patients with spinal cord injury. (3656550)
1987
41
Vesico-ureteral reflux in children with spina bifida and detrusor-sphincter dyssynergia. (6744873)
1984
42
Urodynamic studies in evaluating detrusor sphincter dyssynergia and their effects on the treatment. (6540434)
1984
43
Neurologic aspects of detrusor-sphincter dyssynergia, with reference to the guarding reflex. (7086999)
1982
44
Idiopathic detrusor sphincter dyssynergia in neurologically normal patients with voiding abnormalities. (7060614)
1982
45
Biomechanical basis for recommendation of transurethral sphincterotomy in spinal-cord-injury patients with detrusor-sphincter dyssynergia. (7278408)
1981
46
Pressor response during cystomanometry in spinal injury patients complicated with detrusor-sphincter dyssynergia. (37349)
1979
47
Effect of baclofen and dantrolene on bladder stimulator-induced detrusor-sphincter dyssynergia in dogs. (566976)
1978
48
Detrusor-sphincter dyssynergia and dyssynergic responses: recognition and rationale for early modified transurethral sphincterotomy in complete spinal cord injury lesions. (702671)
1978
49
Detrusor-sphincter dyssynergia and detrusor hyperreflexia leading to hydronephrosis during intermittent catheterization. (712909)
1978
50
The syndrome of detrusor-sphincter dyssynergia. (1053342)
1976

Genetic Variations for Detrusor Sphincter Dyssynergia

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Expression for genes affiliated with Detrusor Sphincter Dyssynergia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Detrusor Sphincter Dyssynergia

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Pathways for genes affiliated with Detrusor Sphincter Dyssynergia

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Compounds for genes affiliated with Detrusor Sphincter Dyssynergia

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GO Terms for genes affiliated with Detrusor Sphincter Dyssynergia

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16Gene Ontology
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Cellular components related to Detrusor Sphincter Dyssynergia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1basement membraneGO:0056049.1EGFL6, CASK

Biological processes related to Detrusor Sphincter Dyssynergia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell adhesionGO:0071559.1EGFL6, CASK
2extracellular matrix organizationGO:0301988.8EGFL6, CASK

Products for genes affiliated with Detrusor Sphincter Dyssynergia

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Sources for Detrusor Sphincter Dyssynergia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet