MCID: DTR001
MIFTS: 22

Detrusor Sphincter Dyssynergia malady

Aliases & Classifications for Detrusor Sphincter Dyssynergia

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Aliases & Descriptions for Detrusor Sphincter Dyssynergia:

Name: Detrusor Sphincter Dyssynergia 10 12
 
Detrusor and Sphincter Dyssynergia 65

External Ids:

Disease Ontology10 DOID:12145
SNOMED-CT59 236655005
ICD9CM29 596.55
UMLS65 C0341747

Summaries for Detrusor Sphincter Dyssynergia

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MalaCards based summary: Detrusor Sphincter Dyssynergia, also known as detrusor and sphincter dyssynergia, is related to breast cancer and schizophrenia. An important gene associated with Detrusor Sphincter Dyssynergia is RPS24 (Ribosomal Protein S24). Affiliated tissues include spinal cord, breast and colon.

Related Diseases for Detrusor Sphincter Dyssynergia

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Graphical network of the top 20 diseases related to Detrusor Sphincter Dyssynergia:



Diseases related to detrusor sphincter dyssynergia

Symptoms for Detrusor Sphincter Dyssynergia

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Drugs & Therapeutics for Detrusor Sphincter Dyssynergia

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Drugs for Detrusor Sphincter Dyssynergia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Darifenacinapproved, investigationalPhase 222133099-04-4444031
Synonyms:
(S)-1-(2-(2,3-Dihydro-5-benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide
(S)-1-(2-(2,3-dihydro-5-Benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide
133099-04-4
2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide
2-{(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacetamide
AC-302
AC1L9FKY
CHEBI:391960
CHEMBL1346
CID444031
D03654
DB00496
 
Darifenacin
Darifenacin (USAN/INN)
Darifenacin Hydrobromide
Darifenacina
Darifenacinum
Darifénacine
Emselex
Enablex
LS-187359
MolPort-005-943-011
NCGC00168775-01
STOCK6S-73577
darifenacin
2
AcetylcholineexperimentalPhase 268951-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
Miochol E
O-Acetylcholine
acetylcholine chloride
3Botulinum ToxinsPhase 2616
4Botulinum Toxins, Type APhase 2588
5IncobotulinumtoxinAPhase 2599
6OnabotulinumtoxinAPhase 2588
7AbobotulinumtoxinAPhase 2588
8Cholinergic AntagonistsPhase 21423
9Muscarinic AntagonistsPhase 2961
10Neurotransmitter AgentsPhase 214795
11Cholinergic AgentsPhase 23243

Interventional clinical trials:

idNameStatusNCT IDPhase
1Clinical Interest of the Temporary Urethral Stent Allium " Bulbar Urethral Stent " in the Treatment of Detrusor Sphincter DyssynergiaRecruitingNCT02323243Phase 1, Phase 2
2Study of Darifenacin in Patients Suffering From Multiple Sclerosis and Neurogenic Detrusor OveractivityTerminatedNCT00845338Phase 2
3Botox-A Injection to Improve Bladder Function in Early Spinal Cord Injury (#H-20344)TerminatedNCT00711087Phase 2
4Neuro-urological Outcome After Spinal Cord InjuryCompletedNCT01297660
5The Effects Upon the Bladder of Transcutaneous Tibial Nerve Stimulation in Acute Traumatic Spinal Cord InjuryNot yet recruitingNCT02573402

Search NIH Clinical Center for Detrusor Sphincter Dyssynergia

Genetic Tests for Detrusor Sphincter Dyssynergia

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Anatomical Context for Detrusor Sphincter Dyssynergia

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MalaCards organs/tissues related to Detrusor Sphincter Dyssynergia:

33
Spinal cord, Breast, Colon, Prostate, T cells, Liver, Endothelial

Animal Models for Detrusor Sphincter Dyssynergia or affiliated genes

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Publications for Detrusor Sphincter Dyssynergia

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Articles related to Detrusor Sphincter Dyssynergia:

(show top 50)    (show all 74)
idTitleAuthorsYear
1
Familial hypertrophic cardiomyopathy caused by a de novo Gly716Arg mutation of the I^-myosin heavy chain. (27161882)
2016
2
Etiology of Pediatric Fever in Western Kenya: A Case-Control Study of Falciparum Malaria, Respiratory Viruses, and Streptococcal Pharyngitis. (25758648)
2015
3
Optimization and Corroboration of the Regulatory Pathway of p42.3 Protein in the Pathogenesis of Gastric Carcinoma. (26106439)
2015
4
Association of interleukin 1 receptor antagonist (IL1RN) gene polymorphism with recurrent pregnancy loss risk in the North Indian Population and a meta-analysis. (24952603)
2014
5
CD151 in cancer progression and metastasis: a complex scenario. (24247563)
2014
6
The usefulness of S100P, mesothelin, fascin, prostate stem cell antigen, and 14-3-3 sigma in diagnosing pancreatic adenocarcinoma in cytological specimens obtained by endoscopic ultrasound guided fine-needle aspiration. (21538952)
2014
7
CD24 expression predicts distant metastasis in extrahepatic bile duct cancer. (23539485)
2013
8
RIF1 counteracts BRCA1-mediated end resection during DNA repair. (23486525)
2013
9
Long-term outcome (22-36 years) of silicone lunate arthroplasty for Kienbock's disease. (23695152)
2013
10
Possible participation of receptor for advanced glycation end products (RAGE) in the origin of cancer stem cells in diabetic patients with colon cancer. (23466064)
2013
11
Altered mRNA expression related to the apoptotic effect of three xanthones on human melanoma SK-MEL-28 cell line. (24175297)
2013
12
Suicide Prevention in College Students: A Collaborative Approach. (24174688)
2013
13
Agonist replacement therapy for cocaine dependence: a translational review. (22300101)
2012
14
Foot-and-mouth disease virus induces autophagosomes during cell entry via a class III phosphatidylinositol 3-kinase-independent pathway. (22993157)
2012
15
Discussion: the use of acellular dermal matrix in immediate two-stage tissue expander breast reconstruction. (22544089)
2012
16
Life with hereditary angioedema: then and now. (22314124)
2012
17
A case of blue rubber bleb nevus syndrome with gastrointestinal and central nervous system involvement. (22010854)
2012
18
Antidepressant response and the serotonin transporter gene-linked polymorphic region. (20615496)
2010
19
Genetic variation of apolipoprotein E does not contribute to the lipid abnormalities secondary to childhood minimal change nephrotic syndrome. (19241136)
2010
20
Ventricular septal defect with bidirectional shunting in a patient with congenitally corrected transposition. (20693120)
2010
21
Peutz-Jeghers syndrome: a study of long-term surgical morbidity and causes of mortality. (20571886)
2010
22
The outcome and prognostic factors in patients with aspiration pneumonia during concurrent chemoradiotherapy for head and neck cancer. (20109165)
2010
23
Global analysis of in vivo EGR1-binding sites in erythroleukemia cell using chromatin immunoprecipitation and massively parallel sequencing. (20690147)
2010
24
Mumps: not an innocent bystander in solid organ transplantation. (19563333)
2009
25
Inflammatory mediators and posterior segment involvement in ocular Behcet disease. (19882576)
2009
26
Unilateral acute conjunctivitis due to ophthalmomyiasis externa caused by larva of Oestrus ovis. (19928747)
2009
27
Galpha12 regulates protein interactions within the MDCK cell tight junction and inhibits tight-junction assembly. (18285450)
2008
28
Metabolism of the trisubstituted purine cyclin-dependent kinase inhibitor seliciclib (R-roscovitine) in vitro and in vivo. (18048486)
2008
29
AAV-HGFK1 and Ad-p53 cocktail therapy prolongs survival of mice with colon cancer. (18790766)
2008
30
Higher frequency of familial clustering of prostate cancer in French-Canadian men. (17698103)
2007
31
Unexplained infant and child death: a review of sudden infant death syndrome, sudden unexplained infant death, and child maltreatment fatalities including shaken baby syndrome. (16601503)
2006
32
Distal renal tubular acidosis associated with isolated large vestibular aqueduct and sensorineural hearing loss. (12018321)
2002
33
Elderly onset rheumatoid arthritis complicated by polymyalgia rheumatica. (12211537)
2002
34
Appraisal of risks from nonoccupational exposure to chlorpyrifos. (11846640)
2002
35
Pro-inflammatory and anti-inflammatory cytokine mRNA induction in the periphery and brain following intraperitoneal administration of bacterial lipopolysaccharide. (11306198)
2001
36
Microtubule-associated protein 1B is a component of cortical Lewy bodies and binds alpha-synuclein filaments. (10764738)
2000
37
HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line. (10985305)
2000
38
Acute effects of recombinant human erythropoietin on plasma levels of proendothelin-1 and endothelin-1 in haemodialysis patients. (9829494)
1998
39
Rhinocerebral zygomycosis. (9610134)
1998
40
Molecular analysis of two putative tumour suppressor genes, PTEN and DMBT, which have been implicated in glioblastoma multiforme disease progression. (9796706)
1998
41
Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells. (9096655)
1997
42
Mutations in the hepatocyte nuclear factor-1alpha gene (MODY3) are not a major cause of late-onset NIDDM in Japanese subjects. (9287055)
1997
43
Patterns of the morbidity and mortality of amebiasis and amebic liver abscess in Mexico: an ecological analysis. (9033105)
1997
44
Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1. (8910295)
1996
45
Phase II study of vorozole (R83842), a new aromatase inhibitor, in postmenopausal women with advanced breast cancer in progression on tamoxifen. (9815984)
1995
46
The synthesis and reactivity of 3 beta-(2-alkynylsulfonyl)- and 3 beta-(2-alkynylsulfonylmethyl) androst-5-en-17-ones as inhibitors of glucose-6-phosphate dehydrogenase. (8539779)
1995
47
Overexpression of the hyaluronan receptor RHAMM is transforming and is also required for H-ras transformation. (7541721)
1995
48
Infantile gynecomastia with bloody nipple discharge. (1552426)
1992
49
Aortic stenosis, myocardial infarction and cardiac rupture: an unusual triad. (15227103)
1984
50
Peutz-Jeghers syndrome and metastasising colonic adenocarcinoma. (6479688)
1984

Variations for Detrusor Sphincter Dyssynergia

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Expression for genes affiliated with Detrusor Sphincter Dyssynergia

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Search GEO for disease gene expression data for Detrusor Sphincter Dyssynergia.

Pathways for genes affiliated with Detrusor Sphincter Dyssynergia

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GO Terms for genes affiliated with Detrusor Sphincter Dyssynergia

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Sources for Detrusor Sphincter Dyssynergia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet