MCID: DVL001
MIFTS: 32

Developmental Coordination Disorder

Categories: Mental diseases

Aliases & Classifications for Developmental Coordination Disorder

MalaCards integrated aliases for Developmental Coordination Disorder:

Name: Developmental Coordination Disorder 12 14 69
Motor Skills Disorders 42 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9923
ICD10 33 F82
ICD9CM 35 315.4
MeSH 42 D019957
NCIt 47 C92561
SNOMED-CT 64 192578006 27544004
UMLS 69 C0011757

Summaries for Developmental Coordination Disorder

Disease Ontology : 12 A specific developmental disorder that involves disordered motor skills where coordinated muscle movement is impaired.

MalaCards based summary : Developmental Coordination Disorder, also known as motor skills disorders, is related to dysgraphia and attention deficit-hyperactivity disorder, and has symptoms including ataxia, clumsiness and abnormal coordination. An important gene associated with Developmental Coordination Disorder is RBFOX1 (RNA Binding Protein, Fox-1 Homolog 1). The drugs Olive and Omega 3 Fatty Acid have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye, and related phenotype is Increased shRNA abundance (Z-score > 2).

Wikipedia : 72 Developmental coordination disorder (DCD), also known as developmental dyspraxia or simply dyspraxia, is... more...

Related Diseases for Developmental Coordination Disorder

Diseases related to Developmental Coordination Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
id Related Disease Score Top Affiliating Genes
1 dysgraphia 10.6
2 attention deficit-hyperactivity disorder 10.3
3 obesity 10.0
4 autism spectrum disorder 10.0
5 specific language impairment 10.0
6 histrionic personality disorder 10.0 ELP4 RBFOX1
7 cerebritis 9.9
8 dyslexia 9.9
9 cerebral palsy 9.8
10 neuronitis 9.8
11 learning disability 9.8
12 schizophrenia 9.7
13 pick disease 9.7
14 autistic disorder 9.7
15 niemann-pick disease 9.7
16 spastic hemiplegia 9.7
17 hemiplegia 9.7
18 parametritis 9.7
19 hypermobility syndrome 9.7
20 vascular disease 9.7
21 epilepsy 9.7
22 infertility 9.7
23 ataxia 9.7
24 developmental dyspraxia 9.7
25 hypotonia 9.7
26 spasticity 9.7
27 leopard syndrome 9.2 KCNK6 LY96
28 chronic canaliculitis 7.0 CHD6 ELP4 FTCD GAP43 KCNK6 LY96

Graphical network of the top 20 diseases related to Developmental Coordination Disorder:



Diseases related to Developmental Coordination Disorder

Symptoms & Phenotypes for Developmental Coordination Disorder

UMLS symptoms related to Developmental Coordination Disorder:


ataxia, clumsiness, abnormal coordination

GenomeRNAi Phenotypes related to Developmental Coordination Disorder according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-101 9.36 ELP4 GAP43
2 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.36 GAP43
3 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.36 ELP4
4 Increased shRNA abundance (Z-score > 2) GR00366-A-163 9.36 ELP4
5 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.36 GAP43
6 Increased shRNA abundance (Z-score > 2) GR00366-A-178 9.36 GAP43
7 Increased shRNA abundance (Z-score > 2) GR00366-A-208 9.36 ELP4
8 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.36 ELP4
9 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.36 GAP43
10 Increased shRNA abundance (Z-score > 2) GR00366-A-6 9.36 ELP4

Drugs & Therapeutics for Developmental Coordination Disorder

Drugs for Developmental Coordination Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Olive Nutraceutical Phase 3
2 Omega 3 Fatty Acid Nutraceutical Phase 3
3 Pharmaceutical Solutions Phase 1
4
Menthol Approved 2216-51-5 16666
5 Hops Approved, Nutraceutical
6
Uric Acid Experimental, Investigational 69-93-2 1175
7 insulin
8 Insulin, Globin Zinc

Interventional clinical trials:

(show all 26)

id Name Status NCT ID Phase Drugs
1 Omega-3/Omega-6 Fatty Acids for Attention-Deficit/Hyperactivity Disorder (ADHD): A Trial in Children and Adolescents Completed NCT01219309 Phase 3
2 Effects of CO-OP Approach on Activity and Participation of Brazilian Children With Developmental Coordination Disorder Recruiting NCT02893852 Phase 1
3 Functional Movement-power Training for Children With Developmental Coordination Disorder: A Randomised Controlled Trial Unknown status NCT02393404
4 The Effect of Virtual Reality on Motor Functioning and Participation Abilities Among Children With DCD Unknown status NCT02504385
5 Characterization of Executive Functions and Patterns of Eye Movements in Children With Developmental Disabilities Unknown status NCT00716235
6 The Effects of a Group-based Gaze Training Intervention for Children With Developmental Coordination Disorder Completed NCT02904980
7 Fitball Program Versus Task-oriented Motor Program on Improving Postural Control in Developmental Coordination Disorder Completed NCT01207544
8 Efficacy of the CO-OP Approach With Brazilian Children With Developmental Coordination Disorder Completed NCT03112746
9 Functional MRI Study in Children With a Developmental Coordination Disorder (DCD) and/or Developmental Dyslexia (DD) Completed NCT02393729
10 Characteristic of Play: Comparison Between Children With Development Coordination Disorder ( DCD) and Children With Typical Development Completed NCT01130038
11 Helping Our Premature Infants ON to Better Motor Skills (HOP-ON) Completed NCT01281358
12 The Role of Brain-derived Neurotropic Factor in the Relationship Between Executive Function and Physical Training Completed NCT02503579
13 Differences in Muscle Activity Patterns and Graphical Product Quality in Children With Graphomotor Impairment Copying and Tracing Activities on Horizontal or Vertical Surfaces Completed NCT02501590
14 Hippotherapy to Improve the Balance of Children With Movement Disorders Completed NCT01313325
15 A Study of Neurophysiologically Based Occupational Therapy Intervention (NBOTI) for Feeding in the NCCU. Completed NCT00766051
16 New Causes and Predictors for the Development of Atrial Fibrillation and Its Complications Completed NCT01863979
17 Rhythmic Motor Learning in Children With Developmental Coordination Disorders Recruiting NCT03150784
18 Taekwondo for Children With Developmental Coordination Disorder Recruiting NCT02635711
19 DCD Imaging-Intervention Study Recruiting NCT02597751
20 Neurobehavioural Development of Infants Born <30 Weeks Gestational Age Between Birth and Five Years of Age Recruiting NCT03172104
21 A Teleintervention in Developmental Coordination Disorder Active, not recruiting NCT03141333
22 Taping for Children With and Without Movement Clumsiness Active, not recruiting NCT02945124
23 Exploring the Impact and Feasibility of a Pathway to Sport and Long-term Participation in Young People Enrolling by invitation NCT02517333
24 Evolution of Maternal Weight During Pregnancy and Influence on the Endothelial Function in Her Offspring Enrolling by invitation NCT02992106
25 Mental Attention-neuromuscular Training for Children With Developmental Coordination Disorder Not yet recruiting NCT02397161
26 Reliability and Validity of a Computerized Tool to Assess Proprioception and Motor Planning Among Children With Coordination Disorders Not yet recruiting NCT03285776

Search NIH Clinical Center for Developmental Coordination Disorder

Cochrane evidence based reviews: motor skills disorders

Genetic Tests for Developmental Coordination Disorder

Anatomical Context for Developmental Coordination Disorder

MalaCards organs/tissues related to Developmental Coordination Disorder:

39
Brain, Testes, Eye, Endothelial, Heart

Publications for Developmental Coordination Disorder

Articles related to Developmental Coordination Disorder:

(show top 50) (show all 506)
id Title Authors Year
1
Cognitive and neuroimaging findings in developmental coordination disorder: new insights from a systematic review of recent research. ( 28872667 )
2017
2
Emotional and behavioural problems in children with Developmental Coordination Disorder: Exploring parent and teacher reports. ( 28915470 )
2017
3
White matter alterations in adults with probable developmental coordination disorder: an MRI diffusion tensor imaging study. ( 27902527 )
2017
4
Gait symmetry in individuals with and without Developmental Coordination Disorder. ( 27912103 )
2017
5
Considerations on the assessment of developmental coordination disorder and the elaboration of related contextual pathways. ( 28650077 )
2017
6
The effect of an integrated perceived competence and motor intervention in children with developmental coordination disorder. ( 27984818 )
2017
7
Occupational therapists' awareness of guidelines for assessment and diagnosis of developmental coordination disorder: Mesure selon laquelle les ergothAcrapeutes connaissent les lignes directrices relatives A l'Acvaluation et au diagnostic du trouble du dAcveloppement de la coordination. ( 28730904 )
2017
8
Children With Developmental Coordination Disorder. ( 28558620 )
2017
9
Understanding why an active video game intervention did not improve motor skill and physical activity in children with developmental coordination disorder: A quantity or quality issue? ( 27863326 )
2017
10
Ripples of influence: Professor Sylvia Rodger's contribution to the body of knowledge on developmental coordination disorder. ( 28714153 )
2017
11
Intervention and management of developmental coordination disorder: Are we providing evidence-based services?: Intervention et traitement d'un trouble du dAcveloppement de la coordination : Les ergothAcrapeutes fournissent-ils des services fondAcs sur les faits scientifiques? ( 28730897 )
2017
12
Mental health outcomes of developmental coordination disorder in late adolescence. ( 28512766 )
2017
13
The Impact of Methylphenidate on Motor Performance in Children with both Attention Deficit Hyperactivity Disorder and Developmental Coordination Disorder: A Randomized Double-Blind Crossover Clinical Trial. ( 28761201 )
2017
14
Impaired postural control in children with developmental coordination disorder is related to less efficient central as well as peripheral control. ( 27693806 )
2017
15
When an object appears unexpectedly: foot placement during obstacle circumvention in children and adults with Developmental Coordination Disorder. ( 28707062 )
2017
16
A Range of Service Delivery Modes for Children With Developmental Coordination Disorder Are Effective: A Randomized Controlled Trial. ( 28654492 )
2017
17
Lack of Motor Inhibition as a Marker of Learning Difficulties of Bimanual Coordination in Teenagers With Developmental Coordination Disorder. ( 28481145 )
2017
18
Feasibility of Motor Imagery Training for Children with Developmental Coordination Disorder - A Pilot Study. ( 28798707 )
2017
19
Nature and Specificity of Gestural Disorder in Children with Developmental Coordination Disorder: A Multiple Case Study. ( 28725201 )
2017
20
Neurobiology of developmental coordination disorder: time to raise our game. ( 28884801 )
2017
21
Procedural learning in Parkinson's disease, specific language impairment, dyslexia, schizophrenia, developmental coordination disorder, and autism spectrum disorders: A second-order meta-analysis. ( 28710941 )
2017
22
Commentary on "A Range of Service Delivery Modes for Children With Developmental Coordination Disorder Are Effective: A Randomized Controlled Trial". ( 28654493 )
2017
23
Appropriateness of different pedagogical approaches to road safety education for children with Developmental Coordination Disorder (DCD). ( 28918308 )
2017
24
Development of motor imagery and anticipatory action planning in children with developmental coordination disorder - A longitudinal approach. ( 28917097 )
2017
25
Insights in Developmental Coordination Disorder. ( 28745216 )
2017
26
Neural changes associated to procedural learning and automatization process in Developmental Coordination Disorder and/or Developmental Dyslexia. ( 27546352 )
2016
27
Attention during functional tasks is associated with motor performance in children with developmental coordination disorder: A cross-sectional study. ( 27631272 )
2016
28
Arterial stiffness in children with and without probable developmental coordination disorder. ( 27552249 )
2016
29
Cognitive-motor interference during fine and gross motor tasks in children with Developmental Coordination Disorder (DCD). ( 27428781 )
2016
30
Gait patterns in children with Developmental Coordination Disorder. ( 26879769 )
2016
31
Adaptations to walking on an uneven terrain for individuals with and without Developmental Coordination Disorder. ( 27591489 )
2016
32
Comparison of motor praxis and performance in children with varying levels of developmental coordination disorder. ( 27101560 )
2016
33
Testing predictive control of movement in children with developmental coordination disorder using converging operations. ( 26861617 )
2016
34
Performance on Functional Strength Measurement and Muscle Power Sprint Test confirm poor anaerobic capacity in children with Developmental Coordination Disorder. ( 27525558 )
2016
35
Cognitive Control of Saccadic Eye Movements in Children with Developmental Coordination Disorder. ( 27812128 )
2016
36
Adaptation and Preliminary Testing of the Developmental Coordination Disorder Questionnaire (DCDQ) for Children in India. ( 27058012 )
2016
37
Developmental coordination disorder and its cause: The road less travelled. ( 27876401 )
2016
38
Action planning and position sense in children with Developmental Coordination Disorder. ( 26796420 )
2016
39
Copy-number variations are enriched for neurodevelopmental genes in children with developmental coordination disorder. ( 27489308 )
2016
40
Self-Regulatory Skill Among Children with and without Developmental Coordination Disorder: An Exploratory Study. ( 26939836 )
2016
41
The effect of strength training based on process approach intervention on balance of children with developmental coordination disorder. ( 27869410 )
2016
42
Are Children At Risk For Developmental Coordination Disorder Weak?: 3666 Board #105 June 4, 8: 00 AM - 9: 30 AM. ( 27362032 )
2016
43
Oculomotor atypicalities in Developmental Coordination Disorder. ( 27753223 )
2016
44
Physical and Mental Health of Children with Developmental Coordination Disorder. ( 27822464 )
2016
45
Neural signature of developmental coordination disorder in the structural connectome independent of comorbid autism. ( 27147441 )
2016
46
Manual function outcome measures in children with developmental coordination disorder (DCD): Systematic review. ( 27062096 )
2016
47
Using an evidence-based online module to improve parents' ability to support their child with Developmental Coordination Disorder. ( 27155793 )
2016
48
Atypical speech lateralization in adults with developmental coordination disorder demonstrated using functional transcranial Doppler ultrasound. ( 26917045 )
2016
49
Developmental Coordination Disorder Plus Oculomotor and Visuospatial Impairment as Neurodevelopmental Heralds of Psychosis Proneness. ( 27996316 )
2016
50
The Impact of Poor Motor Skills on Perceptual, Social and Cognitive Development: The Case of Developmental Coordination Disorder. ( 27014127 )
2016

Variations for Developmental Coordination Disorder

Expression for Developmental Coordination Disorder

Search GEO for disease gene expression data for Developmental Coordination Disorder.

Pathways for Developmental Coordination Disorder

GO Terms for Developmental Coordination Disorder

Sources for Developmental Coordination Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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