MCID: DVL001
MIFTS: 37

Developmental Coordination Disorder

Categories: Mental diseases

Aliases & Classifications for Developmental Coordination Disorder

MalaCards integrated aliases for Developmental Coordination Disorder:

Name: Developmental Coordination Disorder 12 72 14 69
Motor Skills Disorders 41 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9923
ICD10 32 F82
ICD9CM 34 315.4
MeSH 41 D019957
NCIt 46 C92561
SNOMED-CT 64 192578006 27544004

Summaries for Developmental Coordination Disorder

Disease Ontology : 12 A specific developmental disorder that involves disordered motor skills where coordinated muscle movement is impaired.

MalaCards based summary : Developmental Coordination Disorder, also known as motor skills disorders, is related to developmental dyspraxia and dysgraphia, and has symptoms including clumsiness and ataxia. An important gene associated with Developmental Coordination Disorder is RBFOX1 (RNA Binding Fox-1 Homolog 1). The drugs Olive and Omega 3 Fatty Acid have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 72 Developmental coordination disorder (DCD), also known as developmental dyspraxia or simply dyspraxia, is... more...

Related Diseases for Developmental Coordination Disorder

Graphical network of the top 20 diseases related to Developmental Coordination Disorder:



Diseases related to Developmental Coordination Disorder

Symptoms & Phenotypes for Developmental Coordination Disorder

UMLS symptoms related to Developmental Coordination Disorder:


clumsiness, ataxia

GenomeRNAi Phenotypes related to Developmental Coordination Disorder according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-101 9.36 ELP4 GAP43
2 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.36 GAP43
3 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.36 ELP4
4 Increased shRNA abundance (Z-score > 2) GR00366-A-163 9.36 ELP4
5 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.36 GAP43
6 Increased shRNA abundance (Z-score > 2) GR00366-A-178 9.36 GAP43
7 Increased shRNA abundance (Z-score > 2) GR00366-A-208 9.36 ELP4
8 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.36 ELP4
9 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.36 GAP43
10 Increased shRNA abundance (Z-score > 2) GR00366-A-6 9.36 ELP4

Drugs & Therapeutics for Developmental Coordination Disorder

Drugs for Developmental Coordination Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Olive Nutraceutical Phase 3
2 Omega 3 Fatty Acid Nutraceutical Phase 3
3
Menthol Approved 2216-51-5 16666
4 Hops Approved, Nutraceutical
5
Uric Acid Experimental, Investigational 69-93-2 1175
6 Pharmaceutical Solutions
7 insulin
8 Insulin, Globin Zinc

Interventional clinical trials:

(show all 25)

# Name Status NCT ID Phase Drugs
1 Omega-3/Omega-6 Fatty Acids for Attention-Deficit/Hyperactivity Disorder (ADHD): A Trial in Children and Adolescents Completed NCT01219309 Phase 3
2 Mental Attention-neuromuscular Training for Children With Developmental Coordination Disorder Unknown status NCT02397161
3 Functional Movement-power Training for Children With Developmental Coordination Disorder: A Randomised Controlled Trial Unknown status NCT02393404
4 The Effect of Virtual Reality on Motor Functioning and Participation Abilities Among Children With DCD Unknown status NCT02504385
5 Characterization of Executive Functions and Patterns of Eye Movements in Children With Developmental Disabilities Unknown status NCT00716235
6 The Effects of a Group-based Gaze Training Intervention for Children With Developmental Coordination Disorder Completed NCT02904980
7 Efficacy of the CO-OP Approach With Brazilian Children With Developmental Coordination Disorder Completed NCT03112746
8 Fitball Program Versus Task-oriented Motor Program on Improving Postural Control in Developmental Coordination Disorder Completed NCT01207544
9 Functional MRI Study in Children With a Developmental Coordination Disorder (DCD) and/or Developmental Dyslexia (DD) Completed NCT02393729
10 Characteristic of Play: Comparison Between Children With Development Coordination Disorder ( DCD) and Children With Typical Development Completed NCT01130038
11 Helping Our Premature Infants ON to Better Motor Skills (HOP-ON) Completed NCT01281358
12 The Role of Brain-derived Neurotropic Factor in the Relationship Between Executive Function and Physical Training Completed NCT02503579
13 Differences in Muscle Activity Patterns and Graphical Product Quality in Children With Graphomotor Impairment Copying and Tracing Activities on Horizontal or Vertical Surfaces Completed NCT02501590
14 Hippotherapy to Improve the Balance of Children With Movement Disorders Completed NCT01313325
15 A Study of Neurophysiologically Based Occupational Therapy Intervention (NBOTI) for Feeding in the NCCU. Completed NCT00766051
16 Rhythmic Motor Learning in Children With Developmental Coordination Disorders Recruiting NCT03150784
17 Taekwondo for Children With Developmental Coordination Disorder Recruiting NCT02635711
18 DCD Imaging-Intervention Study Recruiting NCT02597751
19 Reliability and Validity of a Computerized Tool to Assess Proprioception and Motor Planning Among Children With Coordination Disorders Recruiting NCT03285776
20 Neurobehavioural Development of Infants Born <30 Weeks Gestational Age Between Birth and Five Years of Age Recruiting NCT03172104
21 A Teleintervention in Developmental Coordination Disorder Active, not recruiting NCT03141333
22 Taping for Children With and Without Movement Clumsiness Active, not recruiting NCT02945124
23 Effects of CO-OP Approach on Activity and Participation of Brazilian Children With Developmental Coordination Disorder Active, not recruiting NCT02893852
24 Exploring the Impact and Feasibility of a Pathway to Sport and Long-term Participation in Young People Enrolling by invitation NCT02517333
25 Evolution of Maternal Weight During Pregnancy and Influence on the Endothelial Function in Her Offspring Enrolling by invitation NCT02992106

Search NIH Clinical Center for Developmental Coordination Disorder

Cochrane evidence based reviews: motor skills disorders

Genetic Tests for Developmental Coordination Disorder

Anatomical Context for Developmental Coordination Disorder

MalaCards organs/tissues related to Developmental Coordination Disorder:

38
Brain, Testes, Eye, Endothelial, Heart, Bone

Publications for Developmental Coordination Disorder

Articles related to Developmental Coordination Disorder:

(show top 50) (show all 527)
# Title Authors Year
1
Corticospinal excitability during motor imagery is reduced in young adults with developmental coordination disorder. ( 29195158 )
2018
2
The brains of children with developmental coordination disorder. ( 29298759 )
2018
3
Developmental coordination disorder, psychopathology and IQ in 22q11.2 deletion syndrome. ( 29433607 )
2018
4
Comparing Attention to Socially-Relevant Stimuli in Autism Spectrum Disorder and Developmental Coordination Disorder. ( 29313185 )
2018
5
Differential activation of brain areas in children with developmental coordination disorder during tasks of manual dexterity: An ALE meta-analysis. ( 29339004 )
2018
6
Participation and needs of children with developmental coordination disorder at home and in the community: Perceptions of children and parents. ( 29245043 )
2018
7
Motor Skill Interventions in Children with Developmental Coordination Disorder: A Systematic Review and Meta-Analysis. ( 29329670 )
2018
8
Sensory and motor differences in Autism Spectrum Conditions and developmental coordination disorder in children: A cross-syndrome study. ( 29408162 )
2018
9
Developmental coordination disorder: the role of executive functions. ( 29333599 )
2018
10
Leg muscle activation patterns during walking and leg lean mass are different in children with and without developmental coordination disorder. ( 29275080 )
2018
11
Success in Adults With Probable Developmental Coordination Disorder Using Structural Equation Modeling. ( 29426379 )
2018
12
Evaluating the evidence for motor-based interventions in developmental coordination disorder: A systematic review and meta-analysis. ( 29413431 )
2018
13
The effect of an integrated perceived competence and motor intervention in children with developmental coordination disorder. ( 27984818 )
2017
14
Gait symmetry in individuals with and without Developmental Coordination Disorder. ( 27912103 )
2017
15
Emotional and behavioural problems in children with Developmental Coordination Disorder: Exploring parent and teacher reports. ( 28915470 )
2017
16
Mental health outcomes of developmental coordination disorder in late adolescence. ( 28512766 )
2017
17
Insights in Developmental Coordination Disorder. ( 28745216 )
2017
18
The Impact of Methylphenidate on Motor Performance in Children with both Attention Deficit Hyperactivity Disorder and Developmental Coordination Disorder: A Randomized Double-Blind Crossover Clinical Trial. ( 28761201 )
2017
19
Nature and Specificity of Gestural Disorder in Children with Developmental Coordination Disorder: A Multiple Case Study. ( 28725201 )
2017
20
Commentary on "A Range of Service Delivery Modes for Children With Developmental Coordination Disorder Are Effective: A Randomized Controlled Trial". ( 28654493 )
2017
21
A Range of Service Delivery Modes for Children With Developmental Coordination Disorder Are Effective: A Randomized Controlled Trial. ( 28654492 )
2017
22
Appropriateness of different pedagogical approaches to road safety education for children with Developmental Coordination Disorder (DCD). ( 28918308 )
2017
23
Cortical activity in fine-motor tasks in children with Developmental Coordination Disorder: A preliminary fNIRS study. ( 29126862 )
2017
24
Intervention and management of developmental coordination disorder: Are we providing evidence-based services?: Intervention et traitement d'un trouble du dAcveloppement de la coordination : Les ergothAcrapeutes fournissent-ils des services fondAcs sur les faits scientifiques? ( 28730897 )
2017
25
Efficacy of the cognitive orientation to daily occupational performance with Brazilian children with developmental coordination disorder. ( 29260603 )
2017
26
Understanding why an active video game intervention did not improve motor skill and physical activity in children with developmental coordination disorder: A quantity or quality issue? ( 27863326 )
2017
27
Cognitive and neuroimaging findings in developmental coordination disorder: new insights from a systematic review of recent research. ( 28872667 )
2017
28
Diversity of activity participation determines bone mineral content in the lower limbs of pre-pubertal children with developmental coordination disorder. ( 29285628 )
2017
29
Occupational therapists' awareness of guidelines for assessment and diagnosis of developmental coordination disorder: Mesure selon laquelle les ergothAcrapeutes connaissent les lignes directrices relatives A l'Acvaluation et au diagnostic du trouble du dAcveloppement de la coordination. ( 28730904 )
2017
30
Executive functions in children with developmental coordination disorder: a 2-year follow-up study. ( 29238952 )
2017
31
Children With Developmental Coordination Disorder. ( 28558620 )
2017
32
Feasibility of Motor Imagery Training for Children with Developmental Coordination Disorder - A Pilot Study. ( 28798707 )
2017
33
When an object appears unexpectedly: foot placement during obstacle circumvention in children and adults with Developmental Coordination Disorder. ( 28707062 )
2017
34
Neurobiology of developmental coordination disorder: time to raise our game. ( 28884801 )
2017
35
Development of motor imagery and anticipatory action planning in children with developmental coordination disorder - A longitudinal approach. ( 28917097 )
2017
36
Corrigendum to "Niemann-Pick Disease Type C Presenting as a Developmental Coordination Disorder with Bullying by Peers in a School-Age Child". ( 29085694 )
2017
37
White matter alterations in adults with probable developmental coordination disorder: an MRI diffusion tensor imaging study. ( 27902527 )
2017
38
Position Sense Dysfunction Affects Proximal and Distal Arm Joints in Children with Developmental Coordination Disorder. ( 29283794 )
2017
39
Considerations on the assessment of developmental coordination disorder and the elaboration of related contextual pathways. ( 28650077 )
2017
40
Lack of Motor Inhibition as a Marker of Learning Difficulties of Bimanual Coordination in Teenagers With Developmental Coordination Disorder. ( 28481145 )
2017
41
Ripples of influence: Professor Sylvia Rodger's contribution to the body of knowledge on developmental coordination disorder. ( 28714153 )
2017
42
Impaired postural control in children with developmental coordination disorder is related to less efficient central as well as peripheral control. ( 27693806 )
2017
43
Developmental Coordination Disorder in a Patient with Mental Disability and a Mild Phenotype Carrying Terminal 6q26-qter Deletion. ( 29270193 )
2017
44
Procedural learning in Parkinson's disease, specific language impairment, dyslexia, schizophrenia, developmental coordination disorder, and autism spectrum disorders: A second-order meta-analysis. ( 28710941 )
2017
45
Development of motor imagery ability in children with developmental coordination disorder - AA goal-directed pointing task. ( 29094756 )
2017
46
Mirror neuron system activation in children with developmental coordination disorder: A replication functional MRI study. ( 29274848 )
2017
47
Light finger contact concurrently reduces postural sway and enhances signal detection performance in children with developmental coordination disorder. ( 26979905 )
2016
48
A Novel Balance Training Program for Children With Developmental Coordination Disorder: A Randomized Controlled Trial. ( 27100457 )
2016
49
Examining the cognitive profile of children with Developmental Coordination Disorder. ( 27258924 )
2016
50
Comparison of motor praxis and performance in children with varying levels of developmental coordination disorder. ( 27101560 )
2016

Variations for Developmental Coordination Disorder

Expression for Developmental Coordination Disorder

Search GEO for disease gene expression data for Developmental Coordination Disorder.

Pathways for Developmental Coordination Disorder

GO Terms for Developmental Coordination Disorder

Molecular functions related to Developmental Coordination Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lyase activity GO:0016829 8.62 FTCD PTS

Sources for Developmental Coordination Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....