MCID: DXT001
MIFTS: 43

Dextrocardia malady

Rare diseases, Cardiovascular diseases, Fetal diseases categories

Summaries for Dextrocardia

About this section
Sources:
44NIH Rare Diseases, 66Wikipedia, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
NIH Rare Diseases:44 Dextrocardia is a condition in which the heart is located in the right side of the chest instead of the left. it is usually present from birth (congenital). there are several types of dextrocardia.  the simplest type occurs when the shape and structure of the heart is a mirror image of a normal heart.  other types of dextrocardia may involve defects of the walls of the heart, nearby blood vessels, or other organs in the abdomen. last updated: 8/4/2011

MalaCards: Dextrocardia, also known as heart predominantly in right hemithorax, is related to situs inversus and dextrocardia with situs inversus. An important gene associated with Dextrocardia is RSPH9 (radial spoke head 9 homolog (Chlamydomonas)). Affiliated tissues include heart, liver and lung, and related mouse phenotypes are skeleton and limbs/digits/tail.

Wikipedia:66 Dextrocardia is a congenital defect in which the apex of the heart is situated on the right side of the... more...

Aliases & Classifications for Dextrocardia

About this section
Sources:
9Disease Ontology, 44NIH Rare Diseases, 11DISEASES, 50Orphanet, 59SNOMED-CT, 36MeSH, 63UMLS, 41NCIt, 37MESH via Orphanet, 27ICD10 via Orphanet, 60SNOMED-CT via Orphanet, 64UMLS via Orphanet
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Fetal diseases
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

dextrocardia 9 44 11 50
heart predominantly in right hemithorax 9


External Ids:

Disease Ontology9 DOID:9565
MeSH36 D003914
NCIt41 C84669
MESH via Orphanet37 D003914
SNOMED-CT59 156925007, 27637000
ICD10 via Orphanet27 Q24.0
SNOMED-CT via Orphanet60 27637000, 74034002
UMLS via Orphanet64 C0011813, C0265863

Related Diseases for Dextrocardia

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Diseases related to Dextrocardia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 112)
idRelated DiseaseScoreTop Affiliating Genes
1situs inversus31.4MEGF8, RSPH9
2dextrocardia with situs inversus10.7
3myocardial infarction10.6
4transposition of the great arteries10.4
5poland syndrome10.4
6ventricular septal defect10.4
7acute myocardial infarction10.3
8double outlet right ventricle10.3
9short stature wormian bones dextrocardia10.3
10bronchiectasis10.3
11tetralogy of fallot10.3
12hypertension10.3
13congenitally corrected transposition of the great arteries10.2
14coronary artery disease10.2
15artery disease10.2
16dextrocardia with unusual facies and microphthalmia10.2
17pagod syndrome10.1
18tricuspid atresia10.1
19aneurysm10.1
20sinusitis10.1
21carpenter syndrome10.0RAB23
22wolff-parkinson-white syndrome10.0
23cleft palate10.0
24scimitar syndrome10.0
25diaphragmatic eventration10.0
26inferior myocardial infarction10.0
27atrioventricular septal defect10.0
28sick sinus syndrome10.0
29right bundle branch block10.0
30congenital heart disease10.0
31lipoma10.0
32mediastinitis10.0
33lung agenesis10.0
34thoraco abdominal enteric duplication10.0
35levocardia10.0
36juxtaposition of the atrial appendages10.0
37angina pectoris9.9
38duodenal ulcer9.9
39rheumatic fever9.9
40congenital heart block9.9
41rheumatic heart disease9.9
42meningocele9.9
43endocardial fibroelastosis9.9
44retinitis pigmentosa9.9
45microphthalmia9.9
46klippel-feil syndrome9.9
47polycystic kidney disease9.9
48esophageal atresia9.9
49infertility9.9
50duodenitis9.9

Graphical network of the top 20 diseases related to Dextrocardia:



Diseases related to dextrocardia

Symptoms for Dextrocardia

About this section

Drugs & Therapeutics for Dextrocardia

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Dextrocardia

Drug clinical trials:

Search ClinicalTrials for Dextrocardia

Search NIH Clinical Center for Dextrocardia

Search CenterWatch for Dextrocardia

Genetic Tests for Dextrocardia

About this section

Anatomical Context for Dextrocardia

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Dextrocardia:

34
Heart, Liver, Lung, Spleen, Kidney, Testes, Testis

Animal Models for Dextrocardia or affiliated genes

About this section
Sources:
38MGI
See all sources

MGI Mouse Phenotypes related to Dextrocardia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.7HES7, ACVR2B, RAB23
2MP:00053718.3HES7, MEGF8, RAB23
3MP:00053808.0HES7, MEGF8, ACVR2B, RAB23

Publications for Dextrocardia

About this section
Sources:
53PubMed
See all sources

Articles related to Dextrocardia:

(show top 50)    (show all 473)
idTitleAuthorsYear
1
A dextrocardia in a foetal Egyptian mummy? (22814111)
2013
2
What is normal in an abnormality? Central venous cannulation in a patient with Situs inversus totalis with dextrocardia and polyCystic kidney disease. (24133338)
2013
3
Slow pathway ablation using electro-anatomical mapping in a patient with corrected transposition of the great arteries, dextrocardia, and atrioventricular nodal reentrant tachycardia. (22764200)
2013
4
Dextrocardia, atrial septal defect, severe developmental delay, facial anomalies, and supernumerary ribs in a child with a complex unbalanced 8;22 translocation including partial 8p duplication. (22302699)
2012
5
Hyperacute anterior myocardial infarction in a patient with dextrocardia and situs inversus. (22710589)
2012
6
Pulmonary vein isolation in a patient with dextrocardia. (23002200)
2012
7
Combined spontaneous contralateral pneumothorax and post-pneumonectomy mediastinal shift-associated dextrocardia. (21243579)
2011
8
Prospectively ECG-triggered 256-slice computed tomography findings in a patient with dextrocardia, stent-treated coarctation, and infracardial right-sided pulmonary vein deviation. (21183498)
2011
9
A rare case of situs inversus with dextrocardia, lutembacher syndrome, and pericardial effusion. (22567197)
2011
10
Repair of postinfarct ventricular septal defect and total myocardial revascularization in a case of dextrocardia with situs inversus. (21225400)
2011
11
Cardiac surgery for annuloaortic ectasia and mitral regurgitation in an adult patient with dextrocardia. (21547628)
2011
12
Percutaneous transvenous mitral commissurotomy in a patient with situs inversus and dextrocardia: a case report. (22577444)
2011
13
Minimally-invasive coronary surgery in dextrocardia and situs inversus totalis. (20847064)
2010
14
Dextrocardia associated with left-sided Poland syndrome. (19169181)
2009
15
Aortopexy for tracheomalacia with dextrocardia, pulmonary artery sling, and congenital tracheal stenosis. (19766841)
2009
16
Emergency off-pump complete arterial revascularization in a patient with dextrocardia. (19908120)
2009
17
Congenitally corrected transposition of the great arteries plus dextrocardia operated with an unusual operative technique. (18704862)
2008
18
Percutaneous mitral commissurotomy in a case of mirror-image dextrocardia and rheumatic mitral stenosis. (18174629)
2008
19
Approach to dextrocardia in adults: review. (17515336)
2007
20
Right diaphragmatic eventration associated with dextrocardia, hypoplasia of the right lower pulmonary lobe, and agenesis of the inferior vena cava. (17467469)
2007
21
Off-pump coronary artery bypass grafting in a high-risk dextrocardia patient: a case report. (15262598)
2004
22
Fatal cardiovascular complications in a patient with Ehlers-Danlos syndrome type IV and dextrocardia. (12453701)
2002
23
Heart block in dextrocardia and situs inversus: a case report. (11686917)
2001
24
A case with dextrocardia, ventricular septal defect, persistent left superior vena cava and drainage of the great cardiac vein into the left internal thoracic vein. (11490934)
2001
25
Myocardial infarction during sleep deprivation in a patient with dextrocardia--a case report. (11205938)
2001
26
An explanation of the unusual electrocardiographic findings in a patient with pulmonary agenesis and dextrocardia. (11447476)
2000
27
A 7-year-old boy with dextrocardia and dysphagia. (10789938)
2000
28
Coronary arteriography in the presence of dextrocardia and situs inversus. (8924024)
1996
29
Covered and duplicate exstrophy with duplication of bladder, urethra, vagina and dextrocardia: a case report. (7747356)
1995
30
Successful directional coronary atherectomy in a patient with dextrocardia and situs inversus. (8495472)
1993
31
On coronary angioplasty in a patient with dextrocardia. (2605636)
1989
32
Interrupted aortic arch, mirror-image dextrocardia with situs inversus and Sprengel's anomaly. (3727028)
1986
33
EKG of the month. Situs inversus totalis (dextrocardia). (6887849)
1983
34
The Mustard procedure in transposition of the great arteries associated with juxtaposition of the atrial appendages with and without dextrocardia. (6827853)
1983
35
EKG of the month. Dextrocardia. (6129216)
1982
36
Inferior myocardial infarction in a patient with mirror-image dextrocardia and situs inversus totalis. (1248285)
1976
37
Dextrocardia, anteroseptal infarction, and fascicular block. (1080097)
1975
38
Dextrocardia with transposition of great vessels and multiple associated abnormalities of viscera. (5202726)
1970
39
Pathologic anatomy of dextrocardia and its clinical implications. (5653057)
1968
40
Surgical treatment of dextrocardia with inversion of ventricles and double-outlet right ventricle. (4170429)
1968
41
ANATOMIC TYPES OF CONGENITAL DEXTROCARDIA: DIAGNOSTIC AND EMBRYOLOGIC IMPLICATIONS. (14136294)
1964
42
THE MODE OF INHERITANCE IN ISOLATED LAEVOCARDIA AND DEXTROCARDIA AND SITUS INVERSUS. (14072604)
1963
43
Combination of dextrocardia, bundle branch block, and myocardial infarction; case report with vector analysis of electrocardiogram. (13594864)
1958
44
Isolated congenital dextrocardia. (14398627)
1955
45
Unusual combination of cardiac anomalies in a case of isolated dextrocardia. (13218010)
1955
46
Posterior ventricular aneurysm in patient with dextrocardia and situs inversus. (13180480)
1954
47
Congenital dextrocardia with situs inversus complicated by hypertension and angina pectoris. (15434816)
1950
48
Simulated dextrocardia associated with bronchiectasis; report of case. (20280493)
1946
49
Dextrocardia and bronchiectasis, a review of the literature and a report of two cases. (20996259)
1946
50
Simple dextrocardia with transposition of the viscera. (21004882)
1945

Variations for Dextrocardia

About this section

Expression for genes affiliated with Dextrocardia

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Dextrocardia

Search GEO for disease gene expression data for Dextrocardia.

Pathways for genes affiliated with Dextrocardia

About this section

Compounds for genes affiliated with Dextrocardia

About this section

GO Terms for genes affiliated with Dextrocardia

About this section
Sources:
17Gene Ontology
See all sources

Biological processes related to Dextrocardia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1BMP signaling pathwayGO:0305099.3ACVR2B, MEGF8
2craniofacial suture morphogenesisGO:0970949.3RAB23, MEGF8
3mesoderm developmentGO:0074988.8ACVR2B, HES7

Products for genes affiliated with Dextrocardia

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Dextrocardia

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet