MCID: DXT001
MIFTS: 43

Dextrocardia malady

Rare diseases, Cardiovascular diseases, Fetal diseases categories
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Summaries for Dextrocardia

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NIH Rare Diseases:42 Dextrocardia is a condition in which the heart is located in the right side of the chest instead of the left. it is usually present from birth (congenital). there are several types of dextrocardia.  the simplest type occurs when the shape and structure of the heart is a mirror image of a normal heart.  other types of dextrocardia may involve defects of the walls of the heart, nearby blood vessels, or other organs in the abdomen. last updated: 8/4/2011

MalaCards based summary: Dextrocardia, also known as heart predominantly in right hemithorax, is related to situs inversus and dextrocardia with situs inversus. An important gene associated with Dextrocardia is RSPH9 (radial spoke head 9 homolog (Chlamydomonas)). Affiliated tissues include heart, lung and liver, and related mouse phenotypes are skeleton and limbs/digits/tail.

Wikipedia:65 Dextrocardia is a congenital defect in which the apex of the heart is situated on the right side of the... more...

Aliases & Classifications for Dextrocardia

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 48Orphanet, 62UMLS, 34MeSH, 39NCIt, 57SNOMED-CT, 63UMLS via Orphanet, 35MESH via Orphanet, 26ICD10 via Orphanet
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Dextrocardia, Aliases & Descriptions:

Name: Dextrocardia 8 42 10 48
 
Heart Predominantly in Right Hemithorax 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Fetal diseases
Anatomical: Cardiovascular diseases


External Ids:

Disease Ontology8 DOID:9565
MeSH34 D003914
NCIt39 C84669
SNOMED-CT57 27637000, 156925007
UMLS via Orphanet63 C0011813, C0265863
MESH via Orphanet35 D003914
ICD10 via Orphanet26 Q24.0

Related Diseases for Dextrocardia

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Diseases related to Dextrocardia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 115)
idRelated DiseaseScoreTop Affiliating Genes
1situs inversus31.3MEGF8, RSPH9
2dextrocardia with situs inversus10.7
3myocardial infarction10.6
4poland syndrome10.4
5transposition of the great arteries10.4
6ventricular septal defect10.4
7acute myocardial infarction10.4
8double outlet right ventricle10.3
9short stature wormian bones dextrocardia10.3
10hypertension10.3
11bronchiectasis10.3
12tetralogy of fallot10.2
13congenitally corrected transposition of the great arteries10.2
14sinusitis10.2
15artery disease10.2
16dextrocardia with unusual facies and microphthalmia10.2
17pagod syndrome10.1
18tricuspid atresia10.1
19aneurysm10.1
20carpenter syndrome10.1RAB23
21wolff-parkinson-white syndrome10.0
22cleft palate10.0
23inferior myocardial infarction10.0
24sick sinus syndrome10.0
25right bundle branch block10.0
26atrioventricular septal defect10.0
27scimitar syndrome10.0
28diaphragmatic eventration10.0
29congenital heart disease10.0
30lipoma10.0
31mediastinitis10.0
32lung agenesis10.0
33thoraco abdominal enteric duplication10.0
34levocardia10.0
35juxtaposition of the atrial appendages10.0
36angina pectoris9.9
37congenital heart block9.9
38congestive heart failure9.9
39hepatitis9.9
40hydrocephalus9.9
41hypoplastic left heart syndrome9.9
42kartagener syndrome9.9
43leukemia9.9
44pulmonary hypertension9.9
45retinitis pigmentosa9.9
46systemic lupus erythematosus9.9
47johanson-blizzard syndrome9.9
48duodenal ulcer9.9
49rheumatic fever9.9
50meningocele9.9

Graphical network of the top 20 diseases related to Dextrocardia:



Diseases related to dextrocardia

Symptoms for Dextrocardia

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Drugs & Therapeutics for Dextrocardia

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Drug clinical trials:

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Genetic Tests for Dextrocardia

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Anatomical Context for Dextrocardia

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MalaCards organs/tissues related to Dextrocardia:

32
Heart, Lung, Liver, Spleen, Kidney, Bone, Testis, Testes

Animal Models for Dextrocardia or affiliated genes

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MGI Mouse Phenotypes related to Dextrocardia:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.7HES7, ACVR2B, RAB23
2MP:00053718.3HES7, MEGF8, RAB23
3MP:00053808.0HES7, MEGF8, ACVR2B, RAB23

Publications for Dextrocardia

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Articles related to Dextrocardia:

(show top 50)    (show all 495)
idTitleAuthorsYear
1
Crisscross heart with dextrocardia and intact interventricular septum. (24701094)
2014
2
Surgical palliation in patients with a single ventricle and dextrocardia. (24534678)
2014
3
Hypoplastic left heart syndrome with dextrocardia and situs solitus. (24668985)
2014
4
To the left-to the right: sustained ventricular bigeminy from the "right" ventricular outflow tract in a patient with dextrocardia. (24444481)
2014
5
A dextrocardia in a foetal Egyptian mummy? (22814111)
2013
6
What is normal in an abnormality? Central venous cannulation in a patient with Situs inversus totalis with dextrocardia and polyCystic kidney disease. (24133338)
2013
7
Slow pathway ablation using electro-anatomical mapping in a patient with corrected transposition of the great arteries, dextrocardia, and atrioventricular nodal reentrant tachycardia. (22764200)
2013
8
Dextrocardia, atrial septal defect, severe developmental delay, facial anomalies, and supernumerary ribs in a child with a complex unbalanced 8;22 translocation including partial 8p duplication. (22302699)
2012
9
Hyperacute anterior myocardial infarction in a patient with dextrocardia and situs inversus. (22710589)
2012
10
Pulmonary vein isolation in a patient with dextrocardia. (23002200)
2012
11
Combined spontaneous contralateral pneumothorax and post-pneumonectomy mediastinal shift-associated dextrocardia. (21243579)
2011
12
Prospectively ECG-triggered 256-slice computed tomography findings in a patient with dextrocardia, stent-treated coarctation, and infracardial right-sided pulmonary vein deviation. (21183498)
2011
13
A rare case of situs inversus with dextrocardia, lutembacher syndrome, and pericardial effusion. (22567197)
2011
14
Repair of postinfarct ventricular septal defect and total myocardial revascularization in a case of dextrocardia with situs inversus. (21225400)
2011
15
Cardiac surgery for annuloaortic ectasia and mitral regurgitation in an adult patient with dextrocardia. (21547628)
2011
16
Minimally-invasive coronary surgery in dextrocardia and situs inversus totalis. (20847064)
2010
17
Dextrocardia associated with left-sided Poland syndrome. (19169181)
2009
18
Lead misplacement vs dextrocardia. (19737172)
2009
19
Aortopexy for tracheomalacia with dextrocardia, pulmonary artery sling, and congenital tracheal stenosis. (19766841)
2009
20
Congenitally corrected transposition of the great arteries plus dextrocardia operated with an unusual operative technique. (18704862)
2008
21
Percutaneous mitral commissurotomy in a case of mirror-image dextrocardia and rheumatic mitral stenosis. (18174629)
2008
22
Approach to dextrocardia in adults: review. (17515336)
2007
23
Right diaphragmatic eventration associated with dextrocardia, hypoplasia of the right lower pulmonary lobe, and agenesis of the inferior vena cava. (17467469)
2007
24
Off-pump coronary artery bypass grafting in a high-risk dextrocardia patient: a case report. (15262598)
2004
25
Fatal cardiovascular complications in a patient with Ehlers-Danlos syndrome type IV and dextrocardia. (12453701)
2002
26
Heart block in dextrocardia and situs inversus: a case report. (11686917)
2001
27
A case with dextrocardia, ventricular septal defect, persistent left superior vena cava and drainage of the great cardiac vein into the left internal thoracic vein. (11490934)
2001
28
Myocardial infarction during sleep deprivation in a patient with dextrocardia--a case report. (11205938)
2001
29
An explanation of the unusual electrocardiographic findings in a patient with pulmonary agenesis and dextrocardia. (11447476)
2000
30
Coronary arteriography in the presence of dextrocardia and situs inversus. (8924024)
1996
31
Successful directional coronary atherectomy in a patient with dextrocardia and situs inversus. (8495472)
1993
32
On coronary angioplasty in a patient with dextrocardia. (2605636)
1989
33
Interrupted aortic arch, mirror-image dextrocardia with situs inversus and Sprengel's anomaly. (3727028)
1986
34
EKG of the month. Situs inversus totalis (dextrocardia). (6887849)
1983
35
The Mustard procedure in transposition of the great arteries associated with juxtaposition of the atrial appendages with and without dextrocardia. (6827853)
1983
36
EKG of the month. Dextrocardia. (6129216)
1982
37
Inferior myocardial infarction in a patient with mirror-image dextrocardia and situs inversus totalis. (1248285)
1976
38
Primary dextrocardia with situs inversus, associated with sinusitis and bronchitis in a dog. (4857725)
1974
39
Dextrocardia with transposition of great vessels and multiple associated abnormalities of viscera. (5202726)
1970
40
Pathologic anatomy of dextrocardia and its clinical implications. (5653057)
1968
41
ANATOMIC TYPES OF CONGENITAL DEXTROCARDIA: DIAGNOSTIC AND EMBRYOLOGIC IMPLICATIONS. (14136294)
1964
42
THE MODE OF INHERITANCE IN ISOLATED LAEVOCARDIA AND DEXTROCARDIA AND SITUS INVERSUS. (14072604)
1963
43
Combination of dextrocardia, bundle branch block, and myocardial infarction; case report with vector analysis of electrocardiogram. (13594864)
1958
44
Isolated congenital dextrocardia. (14398627)
1955
45
Unusual combination of cardiac anomalies in a case of isolated dextrocardia. (13218010)
1955
46
Posterior ventricular aneurysm in patient with dextrocardia and situs inversus. (13180480)
1954
47
Congenital dextrocardia with situs inversus complicated by hypertension and angina pectoris. (15434816)
1950
48
Simulated dextrocardia associated with bronchiectasis; report of case. (20280493)
1946
49
Dextrocardia and bronchiectasis, a review of the literature and a report of two cases. (20996259)
1946
50
Simple dextrocardia with transposition of the viscera. (21004882)
1945

Variations for Dextrocardia

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Expression for genes affiliated with Dextrocardia

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Expression patterns in normal tissues for genes affiliated with Dextrocardia

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Pathways for genes affiliated with Dextrocardia

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Compounds for genes affiliated with Dextrocardia

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GO Terms for genes affiliated with Dextrocardia

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Biological processes related to Dextrocardia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1BMP signaling pathwayGO:0305099.3ACVR2B, MEGF8
2craniofacial suture morphogenesisGO:0970949.3RAB23, MEGF8
3mesoderm developmentGO:0074988.8ACVR2B, HES7

Products for genes affiliated with Dextrocardia

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Sources for Dextrocardia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet