MCID: DFN042
MIFTS: 22

Dfna 3 Nonsyndromic Hearing Loss and Deafness malady

Genetic diseases (common), Ear diseases categories

Summaries for Dfna 3 Nonsyndromic Hearing Loss and Deafness

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MalaCards based summary: Dfna 3 Nonsyndromic Hearing Loss and Deafness is related to gjb6-related dfna 3 nonsyndromic hearing loss and deafness and gjb2-related dfna 3 nonsyndromic hearing loss and deafness. An important gene associated with Dfna 3 Nonsyndromic Hearing Loss and Deafness is GJB6 (gap junction protein, beta 6, 30kDa), and among its related pathways are Myometrial Relaxation and Contraction Pathways and Clathrin derived vesicle budding. The compounds scrambled 10panx and gap 27 have been mentioned in the context of this disorder. Related mouse phenotypes are no phenotypic analysis and hearing/vestibular/ear.

Aliases & Classifications for Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Dfna 3 Nonsyndromic Hearing Loss and Deafness, Aliases & Descriptions:

Name: Dfna 3 Nonsyndromic Hearing Loss and Deafness 21 23


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)
Anatomical: Ear diseases


Related Diseases for Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Graphical network of diseases related to Dfna 3 Nonsyndromic Hearing Loss and Deafness:



Diseases related to dfna 3 nonsyndromic hearing loss and deafness

Symptoms for Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Drugs & Therapeutics for Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Drug clinical trials:

Search ClinicalTrials for Dfna 3 Nonsyndromic Hearing Loss and Deafness

Search NIH Clinical Center for Dfna 3 Nonsyndromic Hearing Loss and Deafness

Genetic Tests for Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Genetic tests related to Dfna 3 Nonsyndromic Hearing Loss and Deafness:

id Genetic test Affiliating Genes
1 Dfna 3 Nonsyndromic Hearing Loss and Deafness21 23 GJB6

Anatomical Context for Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Animal Models for Dfna 3 Nonsyndromic Hearing Loss and Deafness or affiliated genes

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MGI Mouse Phenotypes related to Dfna 3 Nonsyndromic Hearing Loss and Deafness:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030129.1GJB2, GJB6
2MP:00053778.8GJB2, GJB6

Publications for Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Variations for Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Expression for genes affiliated with Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Expression patterns in normal tissues for genes affiliated with Dfna 3 Nonsyndromic Hearing Loss and Deafness

Search GEO for disease gene expression data for Dfna 3 Nonsyndromic Hearing Loss and Deafness.

Pathways for genes affiliated with Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Compounds for genes affiliated with Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Compounds related to Dfna 3 Nonsyndromic Hearing Loss and Deafness according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1scrambled 10panx609.3GJB2, GJB6
2gap 27609.3GJB6, GJB2
3carbenoxolone disodium609.2GJB6, GJB2
410panx609.2GJB2, GJB6
5octanol29 2510.1GJB2, GJB6
6flufenamic acid29 44 3 1212.1GJB6, GJB2
7carbenoxolone44 29 1211.0GJB6, GJB2
8ca2+298.8GJB6, GJB2

GO Terms for genes affiliated with Dfna 3 Nonsyndromic Hearing Loss and Deafness

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Cellular components related to Dfna 3 Nonsyndromic Hearing Loss and Deafness according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1connexon complexGO:0059229.1GJB2, GJB6

Biological processes related to Dfna 3 Nonsyndromic Hearing Loss and Deafness according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1sensory perception of soundGO:0076059.1GJB2, GJB6

Products for genes affiliated with Dfna 3 Nonsyndromic Hearing Loss and Deafness

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Dfna 3 Nonsyndromic Hearing Loss and Deafness

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet