MCID: DFN063
MIFTS: 15

Dfnb 1 Nonsyndromic Hearing Loss and Deafness malady

Categories: Genetic diseases, Ear diseases

Aliases & Classifications for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Aliases & Descriptions for Dfnb 1 Nonsyndromic Hearing Loss and Deafness:

Name: Dfnb 1 Nonsyndromic Hearing Loss and Deafness 24
Dfnb1 Nonsyndromic Hearing Loss and Deafness 24

Classifications:



Summaries for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

MalaCards based summary : Dfnb 1 Nonsyndromic Hearing Loss and Deafness, also known as dfnb1 nonsyndromic hearing loss and deafness, is related to gjb2-related dfnb 1 nonsyndromic hearing loss and deafness and gjb6-related dfnb 1 nonsyndromic hearing loss and deafness. An important gene associated with Dfnb 1 Nonsyndromic Hearing Loss and Deafness is GJB6 (Gap Junction Protein Beta 6), and among its related pathways/superpathways are Myometrial Relaxation and Contraction Pathways and Signaling in Gap Junctions.

Related Diseases for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Diseases related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 31)
id Related Disease Score Top Affiliating Genes
1 gjb2-related dfnb 1 nonsyndromic hearing loss and deafness 12.3
2 gjb6-related dfnb 1 nonsyndromic hearing loss and deafness 12.3
3 dnase1-related susceptibility to systemic lupus erythematosus 10.0 GJB2 GJB6
4 down syndrome-related congenital heart disease 10.0 GJB2 GJB6
5 spastic ataxia, charlevoix-saguenay type 10.0 GJB2 GJB6
6 pik3ca-related segmental overgrowth 10.0 GJB2 GJB6
7 bietti crystalline corneoretinal dystrophy 10.0 GJB2 GJB6
8 pink1 type of young-onset parkinson disease 10.0 GJB2 GJB6
9 keratoderma, palmoplantar, with deafness 10.0 GJB2 GJB6
10 klumpke paralysis 10.0 GJB2 GJB6
11 pseudomyotonia 10.0 GJB2 GJB6
12 ectodermal dysplasia 2, clouston type 10.0 GJB2 GJB6
13 troyer syndrome 10.0 GJB2 GJB6
14 congenital herpes simplex 10.0 GJB2 GJB6
15 molluscum contagiosum 10.0 GJB2 GJB6
16 die smulders droog van dijk syndrome 10.0 GJB2 GJB6
17 bartter syndrome, type 1 10.0 GJB2 GJB6
18 deafness, autosomal dominant 2a 9.9 GJB2 GJB6
19 erythrokeratodermia variabilis et progressiva 9.9 GJB2 GJB6
20 dementia, familial british 9.9 GJB2 GJB6
21 autoimmune gastrointestinal dysmotility 9.9 GJB2 GJB6
22 erythrocytosis due to bisphosphoglycerate mutase deficiency 9.9 GJB2 GJB6
23 cockayne syndrome 9.9 GJB2 GJB6
24 narcissistic personality disorder 9.9 GJB2 GJB6
25 venous insufficiency 9.9 GJB2 GJB6
26 obesity susceptibility, adrb3-related 9.9 GJB2 GJB6
27 telangiectasia macularis eruptiva perstans 9.9 GJB2 GJB6
28 duodenum cancer 9.8 GJB2 GJB6
29 x-linked nonsyndromic deafness 9.8 GJB2 GJB6
30 mitochondrial non-syndromic sensorineural deafness 9.8 GJB2 GJB6
31 solitary bone cyst 9.7 GJB2 GJB6

Graphical network of the top 20 diseases related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness:



Diseases related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Symptoms & Phenotypes for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Drugs & Therapeutics for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Search Clinical Trials , NIH Clinical Center for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Genetic Tests for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Genetic tests related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness:

id Genetic test Affiliating Genes
1 Dfnb 1 Nonsyndromic Hearing Loss and Deafness 24 GJB6

Anatomical Context for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Publications for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Variations for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Expression for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Search GEO for disease gene expression data for Dfnb 1 Nonsyndromic Hearing Loss and Deafness.

Pathways for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Pathways related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.65 GJB2 GJB6
2
Show member pathways
11.35 GJB2 GJB6
3
Show member pathways
10.61 GJB2 GJB6

GO Terms for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Cellular components related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 gap junction GO:0005921 8.96 GJB2 GJB6
2 connexin complex GO:0005922 8.62 GJB2 GJB6

Biological processes related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.32 GJB2 GJB6
2 aging GO:0007568 9.26 GJB2 GJB6
3 sensory perception of sound GO:0007605 9.16 GJB2 GJB6
4 inner ear development GO:0048839 8.96 GJB2 GJB6
5 cell communication GO:0007154 8.62 GJB2 GJB6

Sources for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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