MCID: DFN063
MIFTS: 15

Dfnb 1 Nonsyndromic Hearing Loss and Deafness malady

Categories: Genetic diseases (common), Ear diseases

Aliases & Classifications for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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Aliases & Descriptions for Dfnb 1 Nonsyndromic Hearing Loss and Deafness:

Name: Dfnb 1 Nonsyndromic Hearing Loss and Deafness 24
 
Dfnb1 Nonsyndromic Hearing Loss and Deafness 24

Classifications:



Summaries for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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MalaCards based summary: Dfnb 1 Nonsyndromic Hearing Loss and Deafness, also known as dfnb1 nonsyndromic hearing loss and deafness, is related to gjb2-related dfnb 1 nonsyndromic hearing loss and deafness and gjb6-related dfnb 1 nonsyndromic hearing loss and deafness. An important gene associated with Dfnb 1 Nonsyndromic Hearing Loss and Deafness is GJB6 (Gap Junction Protein Beta 6), and among its related pathways are Myometrial Relaxation and Contraction Pathways and Signaling in Gap Junctions.

Related Diseases for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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Diseases related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 31)
idRelated DiseaseScoreTop Affiliating Genes
1gjb2-related dfnb 1 nonsyndromic hearing loss and deafness12.3
2gjb6-related dfnb 1 nonsyndromic hearing loss and deafness12.3
3dnase1-related susceptibility to systemic lupus erythematosus10.0GJB2, GJB6
4down syndrome-related congenital heart disease10.0GJB2, GJB6
5spastic ataxia, charlevoix-saguenay type10.0GJB2, GJB6
6pik3ca-related segmental overgrowth10.0GJB2, GJB6
7bietti crystalline corneoretinal dystrophy10.0GJB2, GJB6
8pink1 type of young-onset parkinson disease10.0GJB2, GJB6
9keratoderma, palmoplantar, with deafness10.0GJB2, GJB6
10klumpke paralysis10.0GJB2, GJB6
11pseudomyotonia10.0GJB2, GJB6
12ectodermal dysplasia 2, clouston type10.0GJB2, GJB6
13troyer syndrome10.0GJB2, GJB6
14congenital herpes simplex10.0GJB2, GJB6
15molluscum contagiosum10.0GJB2, GJB6
16die smulders droog van dijk syndrome10.0GJB2, GJB6
17bartter syndrome, type 110.0GJB2, GJB6
18deafness, autosomal dominant 2a9.9GJB2, GJB6
19erythrokeratodermia variabilis et progressiva9.9GJB2, GJB6
20dementia, familial british9.9GJB2, GJB6
21autoimmune gastrointestinal dysmotility9.9GJB2, GJB6
22erythrocytosis due to bisphosphoglycerate mutase deficiency9.9GJB2, GJB6
23cockayne syndrome9.9GJB2, GJB6
24narcissistic personality disorder9.9GJB2, GJB6
25venous insufficiency9.9GJB2, GJB6
26obesity susceptibility, adrb3-related9.9GJB2, GJB6
27telangiectasia macularis eruptiva perstans9.9GJB2, GJB6
28duodenum cancer9.8GJB2, GJB6
29x-linked nonsyndromic deafness9.8GJB2, GJB6
30mitochondrial non-syndromic sensorineural deafness9.8GJB2, GJB6
31solitary bone cyst9.7GJB2, GJB6

Graphical network of the top 20 diseases related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness:



Diseases related to dfnb 1 nonsyndromic hearing loss and deafness

Symptoms & Phenotypes for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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Drugs & Therapeutics for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

Genetic Tests for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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Genetic tests related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness:

id Genetic test Affiliating Genes
1 Dfnb 1 Nonsyndromic Hearing Loss and Deafness24 GJB6

Anatomical Context for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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Publications for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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Variations for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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Expression for genes affiliated with Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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Search GEO for disease gene expression data for Dfnb 1 Nonsyndromic Hearing Loss and Deafness.

Pathways for genes affiliated with Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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Pathways related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.1GJB2, GJB6
2
Show member pathways
9.1GJB2, GJB6
3
Show member pathways
9.1GJB2, GJB6

GO Terms for genes affiliated with Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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Cellular components related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1connexin complexGO:00059229.5GJB2, GJB6
2gap junctionGO:00059219.1GJB2, GJB6

Biological processes related to Dfnb 1 Nonsyndromic Hearing Loss and Deafness according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1agingGO:00075689.8GJB2, GJB6
2cell communicationGO:00071549.8GJB2, GJB6
3inner ear developmentGO:00488399.8GJB2, GJB6
4response to lipopolysaccharideGO:00324969.7GJB2, GJB6
5sensory perception of soundGO:00076059.1GJB2, GJB6

Sources for Dfnb 1 Nonsyndromic Hearing Loss and Deafness

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet