MCID: DBT005
MIFTS: 52

Diabetes Insipidus

Categories: Endocrine diseases, Nephrological diseases, Rare diseases, Neuronal diseases

Aliases & Classifications for Diabetes Insipidus

MalaCards integrated aliases for Diabetes Insipidus:

Name: Diabetes Insipidus 12 29 41 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9409
ICD10 33 E23.2
ICD9CM 35 253.5
MeSH 42 D003919
NCIt 47 C43263
SNOMED-CT 64 15771004 190484000
UMLS 69 C0011848

Summaries for Diabetes Insipidus

MedlinePlus : 41 diabetes insipidus (di) causes frequent urination. you become extremely thirsty, so you drink. then you urinate. this cycle can keep you from sleeping or even make you wet the bed. your body produces lots of urine that is almost all water. di is different from diabetes mellitus (dm), which involves insulin problems and high blood sugar. the symptoms can be similar. however, di is related to how your kidneys handle fluids. it's much less common than dm. urine and blood tests can show which one you have. usually, di is caused by a problem with your pituitary gland or your kidneys. treatment depends on the cause of the problem. medicines can often help. nih: national institute of diabetes and digestive and kidney diseases

MalaCards based summary : Diabetes Insipidus is related to diabetes insipidus, nephrogenic and diabetes insipidus, neurohypophyseal. An important gene associated with Diabetes Insipidus is AVP (Arginine Vasopressin), and among its related pathways/superpathways are Neuroscience and Glucose / Energy Metabolism. The drugs Tolvaptan and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and pituitary, and related phenotypes are behavior/neurological and growth/size/body region

Wikipedia : 72 Diabetes insipidus (DI) is a condition characterized by large amounts of dilute urine and increased... more...

Related Diseases for Diabetes Insipidus

Diseases in the Diabetes Insipidus family:

Hereditary Central Diabetes Insipidus Acquired Central Diabetes Insipidus

Diseases related to Diabetes Insipidus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 335)
id Related Disease Score Top Affiliating Genes
1 diabetes insipidus, nephrogenic 12.8
2 diabetes insipidus, neurohypophyseal 12.8
3 diabetes insipidus, nephrogenic, with mental retardation and intracerebral calcification 12.2
4 hereditary central diabetes insipidus 12.2
5 acquired central diabetes insipidus 12.2
6 gestational diabetes insipidus 12.2
7 wolfram syndrome 12.1
8 dipsogenic diabetes insipidus 12.1
9 x-linked intellectual disability-limb spasticity-retinal dystrophy-diabetes insipidus syndrome 11.9
10 wolfram syndrome 2 11.0
11 wolfram-like syndrome, autosomal dominant 10.9
12 polyhydramnios, megalencephaly, and symptomatic epilepsy 10.9
13 hyperostosis frontalis interna 10.9
14 letterer-siwe disease 10.9
15 hashimoto-pritzker syndrome 10.9
16 meester-loeys syndrome 10.8 AVP AVPR2
17 diverticulitis of colon 10.7 AVP AVPR2
18 wernicke-korsakoff syndrome 10.6 AVP REN
19 left-right axis malformations 10.6 AQP2 AVP
20 congenital syphilis 10.6 AQP2 AVP
21 selenium poisoning 10.5 AVP INS
22 cervical alveolar soft part sarcoma 10.4 AVP POMC
23 bagassosis 10.4 AVP POMC
24 macular retinal edema 10.4 AVP POMC
25 generalized anxiety disorder 10.4 AVPR2 POMC
26 seminal vesicle chronic gonorrhea 10.3 AVP POMC
27 repetitive stress injuries 10.3 INS REN
28 cervix uteri carcinoma in situ 10.3 AQP2 AVPR2 REN
29 histiocytosis 10.3
30 long qt syndrome 13 10.3 REN SLC12A1
31 hypopituitarism 10.3
32 monosomy 13q34 10.3 POMC REN
33 cataract 10.2 CRH INS
34 hypodontia of incisors and premolars 10.2 POMC REN
35 idiopathic juxtafoveal retinal telangiectasia 10.2 AQP2 INS
36 cholangiolocellular carcinoma 10.2 POMC REN
37 viral laryngitis 10.2 AQP2 AVP
38 leukemia 10.2
39 internal auditory canal lipoma 10.2 AVP POMC
40 myopia 10.2 AQP2 REN
41 lymphocytic hypophysitis 10.2
42 clear cell acanthoma 10.1 POMC REN
43 renal pelvis carcinoma 10.1 CRH POMC
44 cutis laxa 10.1 INS POMC
45 cerebritis 10.1
46 hypodermyasis 10.1 CRH POMC
47 hypoaldosteronism, congenital, due to cmo ii deficiency 10.1 POMC REN
48 febrile infection-related epilepsy syndrome 10.1 CRH POMC
49 gestational diabetes 10.1
50 pulmonary artery hypoplasia 10.1 REN SLC12A1

Comorbidity relations with Diabetes Insipidus via Phenotypic Disease Network (PDN):


Acute Cystitis Diabetes Insipidus, Nephrogenic
Hypothyroidism Pituitary Hormone Deficiency, Combined, 2

Graphical network of the top 20 diseases related to Diabetes Insipidus:



Diseases related to Diabetes Insipidus

Symptoms & Phenotypes for Diabetes Insipidus

MGI Mouse Phenotypes related to Diabetes Insipidus:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.06 AQP2 AVP AVPR2 CISD2 CRH INS
2 growth/size/body region MP:0005378 9.91 AQP2 AVPR2 CISD2 CRH INS POMC
3 homeostasis/metabolism MP:0005376 9.9 POMC PRL REN SLC12A1 WFS1 AQP2
4 integument MP:0010771 9.61 AQP2 AVPR2 CISD2 CRH INS POMC
5 renal/urinary system MP:0005367 9.28 POMC REN SLC12A1 AQP2 AVP AVPR2

Drugs & Therapeutics for Diabetes Insipidus

Drugs for Diabetes Insipidus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 329)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tolvaptan Approved Phase 4,Phase 3,Phase 2,Phase 1 150683-30-0 216237
2
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 51-43-4 5816
3 Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1
4
Conivaptan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 210101-16-9 151171
5
Norepinephrine Approved Phase 4,Phase 3,Phase 2 51-41-2 439260
6
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-23-7 5754 657311
7
Furosemide Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 54-31-9 3440
8
Misoprostol Approved Phase 4 59122-46-2 5282381
9
Ephedrine Approved Phase 4,Phase 2 299-42-3 9294
10
Oxymetazoline Approved Phase 4,Phase 2 1491-59-4 4636
11
Phenylephrine Approved Phase 4,Phase 2 59-42-7 6041
12
Pseudoephedrine Approved Phase 4,Phase 2 90-82-4 7028
13
Benzocaine Approved Phase 4,Phase 2 1994-09-7, 94-09-7 2337
14
Chlorothiazide Approved, Vet_approved Phase 4 58-94-6 2720
15
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
16
Metolazone Approved Phase 4,Phase 1 17560-51-9 4170
17 tannic acid Approved, Nutraceutical Phase 4,Phase 2
18
Butyric Acid Experimental Phase 4,Phase 3 107-92-6 264
19
Angiotensin II Investigational Phase 4,Phase 1 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
20
Synephrine Experimental Phase 4 1994-07-5, 94-07-5 7172
21 Arginine Vasopressin Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
22 Coagulants Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
23 Deamino Arginine Vasopressin Phase 4,Phase 3,Phase 2,Phase 1
24 Hemostatics Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
25 Natriuretic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
26 Vasopressins Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
27 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
28 Liver Extracts Phase 4,Phase 3,Phase 2,Phase 1
29 Vasoconstrictor Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
30 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1
31 Adrenergic Agonists Phase 4,Phase 3,Phase 2,Phase 1
32 Adrenergic alpha-Agonists Phase 4,Phase 3,Phase 2,Phase 1
33 Adrenergic beta-Agonists Phase 4,Phase 3,Phase 2,Phase 1
34 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Phase 1
35 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
36 Bronchodilator Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Epinephryl borate Phase 4,Phase 3,Phase 2,Phase 1
38 Mydriatics Phase 4,Phase 3,Phase 2,Phase 1
39 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
40 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
42 diuretics Phase 4,Phase 2,Phase 3,Phase 1
43 Oxytocics Phase 4,Phase 2,Phase 1,Early Phase 1
44 Sodium Potassium Chloride Symporter Inhibitors Phase 4,Phase 2,Phase 3,Phase 1
45 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
46 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1
47 Anesthetics Phase 4,Phase 1
48 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
49 Central Nervous System Depressants Phase 4,Phase 2,Phase 3,Phase 1
50 Cortisol succinate Phase 4,Phase 2,Phase 3

Interventional clinical trials:

(show top 50) (show all 391)

id Name Status NCT ID Phase Drugs
1 Pharmacokinetics and Pharmacodynamics of Desmopressin Oral Lyophilisate Formulation in the Paediatric Population Unknown status NCT02584231 Phase 4 desmopressin
2 Desmopressin for Improving Nocturnal Enuresis in Patients After Radical Cystectomy With Bladder Reconstruction Unknown status NCT01582542 Phase 4 Desmopressin
3 Desmopressin Melt Therapy in Nocturnal Polyuria Patients: Pharmacodynamic Study Unknown status NCT01439997 Phase 4 Desmopressin
4 Desmopressin for Bleeding Related to Low Body Temperature Unknown status NCT00902057 Phase 4 desmopressin;desmopressin;desmopressin;placebo
5 Tolvaptan for Hyponatremia in Cirrhotic Patients With Ascites Unknown status NCT01716611 Phase 4 Tolvaptan;placebo
6 Effect of Samsca on Control of Hyponatremia and Extracellular Fluid in Cirrhotic Patients With Ascites Unknown status NCT01552590 Phase 4 Tolvaptan;Placebo
7 Pilot Study of Using Copeptin to Predict Response to Tolvaptan Completed NCT01346072 Phase 4 tolvaptan
8 1-deamino 8-d-arginine Vasopressin (DDAVP) in Percutaneous Ultrasound-guided Renal Biopsy Completed NCT00748072 Phase 4 DDAVP;saline solution
9 Vasopressin and Epinephrine Versus Epinephrine Alone in Cardiac Arrest Completed NCT00127907 Phase 4 epinephrine (1 mg/1 mL);arginine-vasopressin (40 UI/2 mL)
10 Desmopressin in Cardiac Surgery Completed NCT00337766 Phase 4 Desmopressin (DDAVP);Placebo
11 Desmopressin in the Treatment of Mixed Nocturia With Nocturnal Polyuria and Low Nocturnal Bladder Capacity Completed NCT00902655 Phase 4 Desmopressin
12 Study of the Use of Misoprostol to Decrease Bleeding During a Myomectomy Completed NCT01700478 Phase 4 Misoprostol + vasopressin;Vasopressin
13 Desmopressin Melt: Impact on Sleep and Daytime Functioning Completed NCT01645475 Phase 4 Desmopressin lyophilisate (Melt)
14 Effects of Tolvaptan in Healthy Adults Completed NCT01973140 Phase 4 Tolvaptan;Hypertonic saline infusion
15 Effects on Exercise Hemodynamics of Vasopressin Blockade by Conivaptan Infusion in Heart Failure Patients Completed NCT01752543 Phase 4 Conivaptan;Placebo (Dextrose)
16 Effects of Desmopressin on Blood Loss and the Quality of the Surgical Field During Endoscopic Sinus Surgery Completed NCT02125188 Phase 4 Desmopressin;saline
17 Severe Aortic Stenosis and Acquired Von Willebrand´s Disease: The Impact of Desmopressin in Valve-Replacement Surgery Completed NCT01994330 Phase 4 desmopressin
18 Desmopressin Melt Therapy in Patients With Nocturnal Polyuria: a Pharmacokinetic/Dynamic Study Completed NCT01435083 Phase 4 Desmopressin
19 Influence of Food-intake on Desmopressin Oral Tablets and MELT-formulation Completed NCT01036841 Phase 4 desmopressin tablet;desmopressin MELT formulation
20 A Study of Oral Desmopressin in Previously Untreated Children Aged 5 to 15 Years With Primary Nocturnal Enuresis Completed NCT00245479 Phase 4 Primary nocturnal enuresis
21 A 6-week Open Label Cross-over Study With 2 Different Daily Doses of Minirin® Oral Lyophilisate in Children and Adolescents With Primary Nocturnal Enuresis (PNE) Completed NCT00209261 Phase 4 MINIRIN Oral Lyophilisate;Minirin tablet
22 Vasopressin Administration During Laparoscopic Myomectomy: a Randomized Controlled Trial Completed NCT01393704 Phase 4 Vasopressin
23 Comparison of the Effects of Cervical Vasopressin Versus no Premedication on Blood Loss During Vaginal Hysterectomy: A Randomized, Placebo Controlled Trial Completed NCT00799292 Phase 4 Vasopressin
24 Effects of Vasopressors on Immune Response Completed NCT02675868 Phase 4 Norepinephrine;Phenylephrine;Vasopressins;Placebo
25 Effect of Tolvaptan on Mid- to Long-term Prognosis of Heart Failure Patients Completed NCT01439009 Phase 4 Tolvaptan;Placebo of tolvaptan
26 Tolvaptan for Ascites in Cirrhotic Patients Completed NCT01292304 Phase 4 Tolvaptan
27 Tolvaptan in Hyponatremic Cancer Patients Completed NCT01199198 Phase 4 Tolvaptan;Placebo
28 A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia Completed NCT00435591 Phase 4 Conivaptan;placebo
29 Tolvaptan/Ultrafiltration in the Treatment of Acute Heart Failure Completed NCT01863511 Phase 4 loop diuretic;tolvaptan
30 The Safety and Efficacy of Tolvaptan for Patients With Tricuspid Regurgitation and Right Heart Failure After Left Heart Valves Replacement Completed NCT02644616 Phase 4 tolvaptan+torasemide;placebo+torasemide
31 Tolvaptan For Worsening Outpatient Heart Failure: Role of Copeptin In Identifying Responders Recruiting NCT02476409 Phase 4 tolvaptan
32 DDAVP vs. Exercise Recruiting NCT03136003 Phase 4 DDAVP intervention
33 Effect of Dexmedetomidine on Plasmatic Cortisol Response in Transsphenoidal Surgery Recruiting NCT02549768 Phase 4 Dexmedetomidine;Sodium Chloride 0.9%
34 Regional Tolvaptan Registry Recruiting NCT02666651 Phase 4 Tolvaptan
35 Tolvaptan for Advanced or Refractory Heart Failure Recruiting NCT02959411 Phase 4 Tolvaptan;Standard of care diuretic therapy
36 Effect of Vasopressin, Steroid, and Epinephrine Treatment in Patients With Out-of-hospital Cardiac Arrest Recruiting NCT03317197 Phase 4 Control Group;Experimental Group 1;Experimental Group 2;Experimental Group 3
37 Vasoactive Drugs in Intensive Care Unit Recruiting NCT02118467 Phase 4 Norepinephrine;Epinephrine;Phenylephrine;Vasopressin
38 Aquaresis Utility for Hyponatremic Acute Heart Failure Study Recruiting NCT02183792 Phase 4 Tolvaptan;Furosemide
39 NOrepinephrine and VasoprEssin Versus Norepinephrine aLone in Critically Ill Patients With Septic Shock Active, not recruiting NCT02454348 Phase 4 Vasopressin;Norepinephrine
40 Comparison of Oral or Intravenous Thiazides vs Tolvaptan in Diuretic Resistant Decompensated Heart Failure Enrolling by invitation NCT02606253 Phase 4 tolvaptan;Chlorothiazide;Metolazone
41 Vasoactive Hormones and Oxygen Saturation During Apneic Events in Patients With Obstructive Sleep Apnea Suspended NCT00438412 Phase 4
42 Tolvaptan to Reduce Length of Stay in Hospitalized Patients With Cirrhosis and Hyponatremia Terminated NCT01890694 Phase 4 Tolvaptan;Placebo
43 Desmopressin as Treatment for Postoperative Bleeding After Cardiac Surgery Terminated NCT00885924 Phase 4 Desmopressin;Placebo
44 Effect of Desmopressin on the Nocturnal Micturition Frequency in Patients With Parkinson Disease Terminated NCT00806468 Phase 4 Desmotabs
45 Outcome and Treatment Quality Study of Tolvaptan to Treat Hyponatremia in Patients With Heart Failure Terminated NCT02352285 Phase 4 Tolvaptan;Placebo
46 Use of Conivaptan (Vaprisol) for Hyponatremic Neuro-ICU Patients Terminated NCT00727090 Phase 4 Conivaptan
47 Urinary Aquaporine 2 in Patients With Syndrome of Inappropriate ADH-secretion Caused by Treatment With Antiepileptic Medicine Withdrawn NCT00298753 Phase 4
48 Diuretic and Renal Effects of Vaprisol When Administered Along With Furosemide and Nesiritide Continuous Infusion Withdrawn NCT00806910 Phase 4 Conivaptan
49 The Use of Tolvaptan to Prevent Renal Dysfunction in High Risk Patients With Heart Failure-Pilot Study Withdrawn NCT01663662 Phase 4 Tolvaptan;placebo
50 Acute Heart Failure Patients With High Copeptin Treated With Tolvaptan Targets Increased AVP Activation for Treatment (ACTIVATE) Unknown status NCT01733134 Phase 3 Tolvaptan;placebo

Search NIH Clinical Center for Diabetes Insipidus

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: diabetes insipidus

Genetic Tests for Diabetes Insipidus

Genetic tests related to Diabetes Insipidus:

id Genetic test Affiliating Genes
1 Diabetes Insipidus 29

Anatomical Context for Diabetes Insipidus

MalaCards organs/tissues related to Diabetes Insipidus:

39
Heart, Kidney, Pituitary, Testes, Liver, Brain, Lung

Publications for Diabetes Insipidus

Articles related to Diabetes Insipidus:

(show top 50) (show all 1268)
id Title Authors Year
1
Transient Diabetes Insipidus After Discontinuation of Vasopressin in Neurological Intensive Care Unit Patients: Case Series and Literature Review. ( 27742514 )
2017
2
Diabetes insipidus and the use of desmopressin in hospitalised children. ( 28073809 )
2017
3
Tuberculoma of the pituitary gland presenting as diabetes insipidus. ( 28681785 )
2017
4
Mice deficient for ERAD machinery component Sel1L develop central diabetes insipidus. ( 28920918 )
2017
5
Incidence of Diabetes Insipidus in Postoperative Period among the Patients Undergoing Pituitary Tumour Surgery. ( 28919622 )
2017
6
Value of Renal Biopsy in Diagnosing Infantile Nephropathic Cystinosis Associated With Secondary Nephrogenic Diabetes Insipidus. ( 28276300 )
2017
7
Congenital nephrogenic diabetes insipidus complicated with Hinman syndrome. ( 28504419 )
2017
8
Xanthomatous Hypophysitis Presenting with Diabetes Insipidus Completely Cured Through Transsphenoidal Surgery: Case Report and Literature Review. ( 28583458 )
2017
9
Overlap of Post-obstructive Diuresis and Unmasked Diabetes Insipidus in a Case of IgG4-related Retroperitoneal Fibrosis and Tuberoinfundibular Hypophysitis: A Case Report and Review of the Literature. ( 28049999 )
2017
10
Adipsic diabetes insipidus in adult patients. ( 28074401 )
2017
11
A novel SLC12A1 gene mutation associated with hyperparathyroidism, hypercalcemia, nephrogenic diabetes insipidus, and nephrocalcinosis in four patients. ( 28095294 )
2017
12
A case of gestational central diabetes insipidus with oligohydramnios. ( 28764595 )
2017
13
Oral administration of diluted nasal desmopressin in managing neonatal central diabetes insipidus. ( 28599389 )
2017
14
Xanthoma Disseminatum in a Young Patient with Diabetes Insipidus. ( 28523884 )
2017
15
A Case of Osteomyelitis of the toe caused by Coccidioidomycosis in a 17 year-old with Diabetes Insipidus. ( 28560172 )
2017
16
Two Cases of Central Diabetes Insipidus in Refractory Antineutrophil Cytoplasmic Antibody-associated Vasculitis. ( 28943556 )
2017
17
Congenital nephrogenic diabetes insipidus in the Corpus Hippocraticum: The first description. ( 28742510 )
2017
18
Diabetes insipidus and hypopituitarism in HIV: an unexpected cause. ( 28620498 )
2017
19
Pitfall in the Diagnosis of Diabetes Insipidus and Pregnancy. ( 28819576 )
2017
20
Transient Central Diabetes Insipidus and Marked Hypernatremia following Cardiorespiratory Arrest. ( 28758038 )
2017
21
A 42-Year-Old Male with Diabetes Insipidus. ( 28805007 )
2017
22
A Case of Multiple Myeloma Presenting with Diabetes Insipidus. ( 28690897 )
2017
23
Recovery from diabetes insipidus and preservation of thyroid function after craniopharyngioma removal and pituitary stalk sectioning. ( 28917091 )
2017
24
Effect of Preserving the Pituitary Stalk During Resection of Craniopharyngioma in Children on the Diabetes Insipidus and Relapse Rates and Long-Term Outcomes. ( 28749844 )
2017
25
Central Diabetes Insipidus and Hyperglycemic Hyperosmolar State Following Accidental Carbon Monoxide Poisoning. ( 28690939 )
2017
26
Diabetes insipidus after discontinuation of vasopressin infusion for septic shock. ( 28895166 )
2017
27
Opioid-induced hyponatremia in a patient with central diabetes insipidus: independence from ADH. ( 28593907 )
2017
28
Diabetes insipidus is an unfavorable prognostic factor for response to glucocorticoids in patients with autoimmune hypophysitis. ( 28626085 )
2017
29
Cholesteatoma in the Sellar Region Presenting as Hypopituitarism and Diabetes Insipidus. ( 26962793 )
2016
30
A novel AVPR2 gene mutation of X-linked congenital nephrogenic diabetes insipidus in an Asian pedigree. ( 27565746 )
2016
31
Diabetes insipidus: Differential diagnosis and management. ( 27156759 )
2016
32
Bendamustine-Induced Nephrogenic Diabetes Insipidus inA aA Patient With AL Amyloidosis. ( 27780577 )
2016
33
Two novel mutations in seven Czech and Slovak kindreds with familial neurohypophyseal diabetes insipidus-benefit of genetic testing. ( 27539621 )
2016
34
Diabetes insipidus induced by suspected eosinophilic granulomatous with polyangiitis. ( 27807002 )
2016
35
Dengue fever with diffuse cerebral hemorrhages, subdural hematoma and cranial diabetes insipidus. ( 27165581 )
2016
36
Predictor Variables of Developing Anterior Pituitary Deficiencies in a Group of Paediatric Patients with Central Diabetes Insipidus and Langerhans Cell Histiocytosis. ( 27951529 )
2016
37
Unusual Presentation of Central Diabetes Insipidus in a Patient With Neurosarcoidosis. ( 27652275 )
2016
38
Central diabetes insipidus. ( 28008190 )
2016
39
Partial Nephrogenic Diabetes Insipidus in a Burned Patient Receiving Sevoflurane Sedation With an Anaesthetic Conserving Device-A Case Report. ( 27414478 )
2016
40
A case of central diabetes insipidus associated with cardiac dysfunction. ( 27980741 )
2016
41
Spontaneous intermittent MRI changes of a pituitary stalk lesion causing diabetes insipidus and amenorrhea. ( 27655292 )
2016
42
4-PBA Improves Lithium-induced Nephrogenic Diabetes Insipidus by Attenuating ER Stress. ( 27385737 )
2016
43
Analysis of the V2 vasopressin receptor (V2R) mutations causing partial nephrogenic diabetes insipidus highlights a sustainable signaling by a non-peptide V2R agonist. ( 27601473 )
2016
44
Prevalence and risk factors for central diabetes insipidus in cardiac arrest survivor treated with targeted temperature management. ( 27133533 )
2016
45
Poster 365 Traumatic Brain Injury Resulting from Pontine and Extrapontine Myelinolysis due to Acute Onset of Pregnancy Induced Diabetes Insipidus: A Case Report. ( 27673118 )
2016
46
Pituitary Morphology and Function in 43 Children with Central Diabetes Insipidus. ( 27118970 )
2016
47
Genetic forms of neurohypophyseal diabetes insipidus. ( 27156762 )
2016
48
INCIDENCE OF CENTRAL DIABETES INSIPIDUS IN CHILDREN PRESENTING WITH POLYDIPSIA AND POLYURIA. ( 27540876 )
2016
49
Acetazolamide in Lithium-Induced Nephrogenic Diabetes Insipidus. ( 27959610 )
2016
50
A novel AVPR2 splice site mutation leads to partial X-linked nephrogenic diabetes insipidus in two brothers. ( 26795631 )
2016

Variations for Diabetes Insipidus

Expression for Diabetes Insipidus

Search GEO for disease gene expression data for Diabetes Insipidus.

Pathways for Diabetes Insipidus

GO Terms for Diabetes Insipidus

Cellular components related to Diabetes Insipidus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 endosome lumen GO:0031904 8.62 INS PRL

Biological processes related to Diabetes Insipidus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.76 AVP AVPR2 CRH INS
2 positive regulation of gene expression GO:0010628 9.62 AVP AVPR2 CRH INS
3 positive regulation of vasoconstriction GO:0045907 9.43 AVP AVPR2
4 response to immobilization stress GO:0035902 9.4 CRH REN
5 water transport GO:0006833 9.37 AQP2 AVP
6 glucose homeostasis GO:0042593 9.26 INS WFS1
7 positive regulation of systemic arterial blood pressure GO:0003084 9.16 AVP AVPR2
8 excretion GO:0007588 9.13 AQP2 AVPR2 CLCNKA
9 renal water homeostasis GO:0003091 8.92 AQP2 AVP AVPR2 WFS1

Molecular functions related to Diabetes Insipidus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.56 AVP CRH POMC REN
2 insulin-like growth factor receptor binding GO:0005159 9.16 INS REN
3 hormone activity GO:0005179 9.02 AVP CRH INS POMC PRL
4 neuropeptide hormone activity GO:0005184 8.96 AVP CRH

Sources for Diabetes Insipidus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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