MCID: DBT009
MIFTS: 80

Diabetes Mellitus malady

Endocrine diseases category

Summaries for Diabetes Mellitus

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Sources:
33MedlinePlus, 3CDC, 45Novus Biologicals, 63Wikipedia, 46OMIM, 32MalaCards
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MedlinePlus:33 Diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. glucose comes from the foods you eat. insulin is a hormone that helps the glucose get into your cells to give them energy. with type 1 diabetes, your body does not make insulin. with type 2 diabetes, the more common type, your body does not make or use insulin well. without enough insulin, the glucose stays in your blood. over time, having too much glucose in your blood can cause serious problems. it can damage your eyes, kidneys, and nerves. diabetes can also cause heart disease, stroke and even the need to remove a limb. pregnant women can also get diabetes, called gestational diabetes. a blood test can show if you have diabetes. exercise, weight control and sticking to your meal plan can help control your diabetes. you should also monitor your glucose level and take medicine if prescribed. nih: national institute of diabetes and digestive and kidney diseases

MalaCards: Diabetes Mellitus, also known as diabetes, is related to type 2 diabetes mellitus and gestational diabetes. An important gene associated with Diabetes Mellitus is IL6 (interleukin 6 (interferon, beta 2)), and among its related pathways are Type II diabetes mellitus and Regulation of beta-cell development. The drug chromium picolinate and the compounds glucose and arginine have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and kidney, and related mouse phenotypes are homeostasis/metabolism and mortality/aging.

CDC:3 CDC's Division of Diabetes Translation translates diabetes research into daily practice to understand the impact of the disease, influence health outcomes, and improve access to quality health care.

Novus Biologicals:45 Diabetes is a disease in which the body does not produce or properly use insulin. There are four major types of diabetes: Type 1, Type 2, Gestational and Pre-Diabetes. Type 1 diabetes, previously known as juvenile diabetes, is an autoimmune disease resulting when one's own immune system destroys insulin-producing beta cells in the pancreas. This causes the pancreas to produce little or no insulin. In type 2 diabetes, the body either does not produce enough insulin or beta cells ignore insulin. Gestational diabetes refers to high glucose levels caused by pregnancy. Pre-diabetes is a condition in which blood glucose levels are high, but not high enough for the diagnosis of type 2 diabetes.

Wikipedia:63 Diabetes mellitus (DM) or simply diabetes, is a group of metabolic diseases in which a person has high... more...

Description from OMIM:46 222100

Aliases & Classifications for Diabetes Mellitus

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 46OMIM, 33MedlinePlus, 39NCIt, 56SNOMED-CT, 34MeSH, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Endocrine diseases
ICD10: 25



Aliases & Descriptions:

diabetes mellitus 8 10 44 60
diabetes 8 46 33 60
diabetes nos 8


Related Diseases for Diabetes Mellitus

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Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Type 2 Diabetes Mellitus family:

Type 1 Diabetes Mellitus diabetes mellitus

Diseases related to Diabetes Mellitus via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 1415)
idRelated DiseaseScoreTop Affiliating Genes
1type 2 diabetes mellitus32.4SLC2A4, HNF1B
2gestational diabetes31.9PTPRN, SLC2A4, ABCC8, LEP, IAPP, CAPN10
3obesity31.7SLC2A4, ABCC8, LEP, IL6, IAPP, AKR1B1
4neonatal diabetes mellitus31.6PLAGL1, ABCC8, PDX1, HNF1B, GCK, KCNJ11
5hypertension31.6LEP
6neuropathy31.5AKR1B1
7pancreatitis31.5IL6
8diabetic retinopathy31.4AKR1B1
9atherosclerosis31.3LEP, IL6, AKR1B1, CAPN10
10hepatitis31.2CTLA4, HGF
11hyperglycemia31.2PTPRN, SLC2A2, SLC2A4, ABCC8, LEP, IAPP
12permanent neonatal diabetes mellitus31.2ABCC8, KCNJ11
13thyroiditis31.2CTLA4
14hypoglycemia31.2AKR1B1, GCK, KCNJ11, IAPP, SLC2A2, SLC2A4
15type 1 diabetes31.1PTPRN, CTLA4, GCK
16myocardial infarction31.1AKR1B1, PDX1
17celiac disease31.1CTLA4
18glucose intolerance31.0KCNJ11, GCK, SLC2A2, SLC2A4, ABCC8, LEP
19periodontal disease30.9IL6
20ischemia30.8GCK, HGF, AKR1B1, ABCC8, SLC2A4
21essential hypertension30.8LEP, IAPP
22hypothyroidism30.8LEP, CTLA4
23polycystic ovary syndrome30.7CAPN10, LEP, SLC2A4
24maturity-onset diabetes of the young30.7KCNJ11, GCK, HNF1B, PDX1, NEUROD1
25proliferative diabetic retinopathy30.7HGF
26hyperinsulinism30.7KCNJ11, GCK, LEP, ABCC8
27insulinoma30.7PTPRN, SLC2A2, ABCC8, IAPP, WFS1, PDX1
28liver cirrhosis30.6SLC2A4, LEP, HGF, GCK
29morbid obesity30.6LEP
30cystic fibrosis30.6KCNJ11, CAPN10, ABCC8
31cataract30.6AKR1B1, CAPN10
32hyperandrogenism30.5LEP, CAPN10
33pancreatic cancer30.5HGF, PDX1, IAPP, SLC2A4
34hyperthyroidism30.5CTLA4, LEP
35acute pancreatitis30.5IAPP, IL6
36prostate cancer30.4HNF1B, HGF, CTLA4, IL6
37myopathy30.4SLC2A4
38galactosemia30.3HNF1B, HGF, CTLA4, LEP
39diabetes mellitus, noninsulin-dependent30.2HNF1B, NEUROD1, ABCC8, SLC2A4
40hyperinsulinemic hypoglycemia30.2ABCC8, GCK, KCNJ11
41adenoma30.2PLAGL1, CTLA4
42hyperuricemia30.2GCK, HNF1B
43adenocarcinoma30.1HNF1B, HGF, PDX1, NEUROD1, IAPP, SLC2A4
44metabolic syndrome x30.1SLC2A4, LEP
45vitiligo30.1CTLA4
46myeloma30.1IL6, HGF
47pheochromocytoma30.0IAPP
48chronic kidney failure29.9HNF1B, HGF, AKR1B1, IL6, LEP
49pituitary adenoma29.9ABCC8, LEP, NEUROD1
50beckwith-wiedemann syndrome29.9ZFP57, ABCC8, PLAGL1

Graphical network of the top 20 diseases related to Diabetes Mellitus:



Diseases related to diabetes mellitus

Clinical Features for Diabetes Mellitus

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Sources:
46OMIM
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Clinical features from OMIM:

222100

Drugs & Therapeutics for Diabetes Mellitus

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Diabetes Mellitus

Drug clinical trials:

Search ClinicalTrials for Diabetes Mellitus

Search NIH Clinical Center for Diabetes Mellitus

Search CenterWatch for Diabetes Mellitus

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Diabetes Mellitus

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Anatomical Context for Diabetes Mellitus

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32MalaCards
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MalaCards organs/tissues related to Diabetes Mellitus:

32
Heart, Endothelial, Kidney, Testes, Pancreas, Liver, Thyroid, Bone, Eye, Skeletal muscle, Monocytes, Brain, Pancreatic islet, T cells, Ovary, Skin, Placenta, Pituitary, Adipocyte, Lung, Breast, B cells, Prostate, Colon, Smooth muscle, Retina, Pons, Myeloid, Bone marrow, Small intestine, Whole blood, Tongue, Hypothalamus, Spleen, Spinal cord, Thymus, Cortex, Testis

Animal Models for Diabetes Mellitus or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Diabetes Mellitus:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537614.0PTPRN, KCNJ11, GCK, HNF1B, CAPN10, ICA1
2MP:001076813.5CTLA4, PDX1, ICA1, HGF, HNF1B, GCK
3MP:000537813.4PDX1, CAPN10, HGF, HNF1B, GCK, KCNJ11
4MP:000537913.2CTLA4, PDX1, CAPN10, HNF1B, GCK, KCNJ11
5MP:000538712.3HNF1B, CAPN10, ICA1, PDX1, CTLA4, IAPP
6MP:000537012.2GCK, HNF1B, HGF, CAPN10, PDX1, CTLA4
7MP:000536712.0GCK, HNF1B, CAPN10, PDX1, AKR1B1, NEUROD1
8MP:000538511.8KCNJ11, HGF, CAPN10, CTLA4, IL6, LEP
9MP:001077111.5KCNJ11, PDX1, CTLA4, WFS1, IL6, LEP
10MP:000537511.4SLC2A4, LEP, IL6, CAPN10, KCNJ11

Publications for Diabetes Mellitus

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Sources:
50PubMed
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Articles related to Diabetes Mellitus:

(show top 50)    (show all 7777)
idTitleAuthorsYear
1
Higher prevalence of gestational diabetes mellitus following assisted reproduction technology treatment. (23814097)
2013
2
Glucose-6-phosphate dehydrogenase deficiency and diabetes mellitus with severe retinal complications in a sardinian population, Italy. (24324368)
2013
3
Role of exercise in the management of diabetes mellitus: the global scenario. (24236181)
2013
4
Spectrum of skin changes secondary to insulin injections in Type 1 diabetes mellitus patients. (23302026)
2013
5
Canagliflozin: Effects in overweight and obese subjects without diabetes mellitus. (24227660)
2013
6
Newly diagnosed diabetes mellitus after acute pancreatitis: a systematic review and meta-analysis. (23929695)
2013
7
Peripheral polyneuropathy and female sexual dysfunction--familial amyloidotic polyneuropathy as an example besides diabetes mellitus. (23217031)
2013
8
Thyroid disorders in patients of type 2 diabetes mellitus. (24426234)
2013
9
Microvascular complications in adolescents with type 1 diabetes mellitus. (24072081)
2013
10
Improved post-partum follow-up of patients with gestational diabetes mellitus using HbA1c. (23865823)
2013
11
Exploring the role of Mycobacterium avium subspecies paratuberculosis in the pathogenesis of type 1 diabetes mellitus: a pilot study. (23759115)
2013
12
Value of renal resistive index as an early marker of diabetic nephropathy in children with type-1 diabetes mellitus. (22982911)
2012
13
HLA-DQB1* alleles and genetic susceptibility to type 1 diabetes mellitus. (22919445)
2012
14
Insulinoma in a patient with type 2 diabetes mellitus proved at autopsy. (23246687)
2012
15
Histological predictors for renal prognosis in diabetic nephropathy in diabetes mellitus type 2 patients with overt proteinuria. (21933307)
2012
16
Low serum osteoprotegerin levels in normoalbuminuric type 1 diabetes mellitus. (19784545)
2010
17
Long-term Escherichia coli asymptomatic bacteriuria among women with diabetes mellitus. (19583518)
2009
18
Primary endobronchial actinomycosis simulating endobronchial tuberculosis in a patient with diabetes mellitus. (17602348)
2007
19
Adiponectin is associated with brain natriuretic peptide and left ventricular hypertrophy in hemodialysis patients with type 2 diabetes mellitus. (17890872)
2007
20
Common variants in MODY genes increase the risk of gestational diabetes mellitus. (16752173)
2006
21
Cardiovascular/non-insulin-dependent diabetes mellitus risk factors and intramyocellular lipid in healthy subjects: a sex comparison. (16324931)
2006
22
Effects of rosiglitazone and pioglitazone combined with metformin on the prothrombotic state of patients with type 2 diabetes mellitus and metabolic syndrome. (17133785)
2006
23
Vascular ossification-calcification in metabolic syndrome, type 2 diabetes mellitus, chronic kidney disease, and calciphylaxis-calcific uremic arteriolopathy: the emerging role of sodium thiosulfate. (15777477)
2005
24
Association analysis of the variant in the regulatory subunit of phosphoinositide 3-kinase (p85alpha) with Type 2 diabetes mellitus and hypertension in the Chinese Han population. (15910625)
2005
25
Effectiveness of weight loss in the elderly with type 2 diabetes mellitus. (16483174)
2005
26
Concealed renal failure and adverse drug reactions in older patients with type 2 diabetes mellitus. (16183954)
2005
27
Association of CETP TaqI and APOE polymorphisms with type II diabetes mellitus in North Indians: a case control study. (15992403)
2005
28
Statin use in Type 2 diabetes mellitus is associated with a delay in starting insulin. (15317599)
2004
29
Pioglitazone in the management of diabetes mellitus after transplantation. (15575920)
2004
30
Type 1 diabetes mellitus in Catalonia: chronic complications and metabolic control ten years after onset. (15114267)
2004
31
Pregnancy outcome in Type 1 diabetes mellitus treated with insulin lispro (Humalog). (12519319)
2003
32
Polymorphisms in fatty acid-binding protein-3 (FABP3) - putative association with type 2 diabetes mellitus. (12872269)
2003
33
Study on the relationship between mitochondrial gene mutation and latent autoimmune diabetes mellitus in adults. (12906157)
2002
34
Should all patients with type 1 diabetes mellitus and microalbuminuria receive angiotensin-converting enzyme inhibitors? A meta-analysis of individual patient data. (11242497)
2001
35
Clinical features of a polymorphism of the beta3-adrenergic receptor gene in patients with type 2 diabetes mellitus--a study using a pin-point sequencing method. (11573151)
2001
36
Diabetes mellitus in newborns and infants. (10932965)
2000
37
Permanent neonatal diabetes mellitus: epidemiology, mode of presentation, pathogenesis and growth. (10798084)
1999
38
Analysis of trinucleotide-repeat combination polymorphism at the rad gene in patients with type 2 diabetes mellitus. (10024077)
1999
39
The effects of recombinant human IGF-I administration on concentrations of acid labile subunit, IGF binding protein-3, IGF-I, IGF-II and proteolysis of IGF binding protein-3 in adolescents with insulin-dependent diabetes mellitus. (9614361)
1998
40
Relation between insulin resistance and small, dense lipoproteins with low density and the development of atherosclerosis in type 2 diabetes mellitus]. (9919742)
1998
41
Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. (9502634)
1998
42
Clinical evaluation of non-insulin-dependent diabetes mellitus patients with autoantibodies to glutamic acid decarboxylase. (8933285)
1996
43
A case from practice (350). Mesangioproliferative glomerulonephritis (IgA nephritis)--nephrotic syndrome. Type II diabetes mellitus. Arterial hypertension (WHO-stage II)--grade II fundus hypertension. Chronic bronchitis following long-term nicotine abuse]. (8685566)
1996
44
A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus. (7773293)
1995
45
Molecular screening of the lipoprotein lipase gene in hypertriglyceridemic members of familial noninsulin-dependent diabetes mellitus families. (7962342)
1994
46
Nicotinamide treatment in the prevention of insulin-dependent diabetes mellitus. (7924827)
1993
47
Application of the box plot to evaluate serum lipid levels and apolipoprotein levels in patients with cerebral infarction and diabetes mellitus]. (2352345)
1990
48
Insulin insensitivity in offspring of parents with type 2 diabetes mellitus. (1967567)
1990
49
Special health problems of Mexican-Americans: obesity, gallbladder disease, diabetes mellitus, and cardiovascular disease. (2644769)
1989
50
Renal vascular disease in diabetes mellitus. (13107537)
1953

Genetic Variations for Diabetes Mellitus

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Expression for genes affiliated with Diabetes Mellitus

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Diabetes Mellitus

Search GEO for disease gene expression data for Diabetes Mellitus.

Pathways for genes affiliated with Diabetes Mellitus

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Sources:
29KEGG, 37NCBI BioSystems Database, 49PharmGKB, 53Reactome, 51QIAGEN, 12EMD Millipore, 4Cell Signaling Technology
See all sources

Pathways related to Diabetes Mellitus according to GeneCards/GeneDecks:

(show all 14)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
11.9SLC2A2, KCNJ11, GCK, HNF1B, PDX1, NEUROD1
2
Hide members
11.6GCK, HNF1B, PDX1, NEUROD1, IAPP, SLC2A2
311.4KCNJ11, GCK, PDX1, ABCC8, SLC2A2
411.4KCNJ11, GCK, PDX1, ABCC8, SLC2A2
5
Hide members
11.4IAPP, NEUROD1, PDX1, HNF1B, GCK
6
Hide members
11.4HGF, IL6, SLC2A4, SLC2A2, PTPRN
7
Development Leptin signaling via PI3K-dependent pathway
Hide members
11.2KCNJ11, LEP, ABCC8, SLC2A4
811.2SLC2A2, IAPP, PDX1, HNF1B
911.2SLC2A4, WFS1, NEUROD1, PDX1
10
Hide members
11.0SLC2A2, ABCC8, KCNJ11
11
Hide members
11.0SLC2A2, SLC2A4, GCK
12
Hide members
11.0GCK, SLC2A4, SLC2A2
1310.8KCNJ11, ABCC8
1410.8SLC2A2, SLC2A4

Compounds for genes affiliated with Diabetes Mellitus

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB, 59Tocris Bioscience, 28IUPHAR
See all sources

Compounds related to Diabetes Mellitus according to GeneCards/GeneDecks:

(show top 50)    (show all 82)
idCompoundScoreTop Affiliating Genes
1glucose4413.7IAPP, ABCC8, SLC2A4, SLC2A2, PTPRN, LEP
2arginine4412.9KCNJ11, PTPRN, GCK, HNF1B, HGF, ABCC8
3calcium44 49 11 2415.6WFS1, CTLA4, NEUROD1, CAPN10, HGF, ABCC8
4lipid4412.5CTLA4, CAPN10, IAPP, GCK, IL6, ABCC8
5serine4412.4LEP, PDX1, CTLA4, AKR1B1, IAPP, ABCC8
6testosterone44 59 11 2415.4PLAGL1, IAPP, SLC2A4, LEP, ABCC8, HGF
7cholesterol44 28 11 2415.4LEP, HNF1B, CTLA4, ABCC8, IL6, CAPN10
8glutamate4412.3ICA1, GCK, KCNJ11, HGF, LEP, ABCC8
9sulfonylurea4412.2KCNJ11, GCK, PDX1, IAPP, ABCC8, SLC2A4
10c-peptide4412.2IAPP, GCK, KCNJ11, PTPRN, SLC2A2, LEP
11glycogen44 2413.2SLC2A4, IAPP, CAPN10, HGF, ABCC8, GCK
12creatinine4412.2SLC2A4, AKR1B1, IL6, LEP, HGF, GCK
13h2o24412.1GCK, HGF, AKR1B1, LEP, SLC2A4, IAPP
14dexamethasone44 49 28 1115.1SLC2A4, LEP, IL6, IAPP, CTLA4, HGF
15streptozotocin4412.0SLC2A4, SLC2A2, AKR1B1, IAPP, PDX1, GCK
16metformin44 49 1114.0KCNJ11, GCK, IAPP, LEP, SLC2A4, ABCC8
17retinoic acid44 2413.0SLC2A4, IL6, GCK, NEUROD1, PDX1, HGF
18indomethacin44 59 28 1115.0LEP, AKR1B1, IL6, HGF, SLC2A4, IAPP
19ly2940024412.0GCK, SLC2A4, LEP, IL6, CTLA4, HGF
20cysteine4412.0CTLA4, LEP, AKR1B1, CAPN10, IAPP, ABCC8
21potassium44 11 2413.9HGF, SLC2A2, ABCC8, CAPN10, KCNJ11, GCK
22cyclosporin a44 28 5913.9IL6, LEP, CTLA4, HGF, PTPRN, AKR1B1
23lactate4411.9GCK, HGF, SLC2A4, AKR1B1, IL6, IAPP
24katp4411.8PDX1, KCNJ11, SLC2A2, ABCC8, GCK
25glibenclamide44 28 49 5914.8IAPP, LEP, ABCC8, SLC2A4, KCNJ11
26pyruvate4411.7HGF, PDX1, GCK, SLC2A4, SLC2A2
27n acetylcysteine4411.7AKR1B1, PDX1, LEP, IL6, HGF
28incretin4411.6IAPP, GCK, PDX1, SLC2A2
29repaglinide44 49 1113.6ABCC8, KCNJ11, IAPP, NEUROD1
30wortmannin4411.6PDX1, CTLA4, LEP, SLC2A4, HGF
31nicotinamide44 1112.6PDX1, AKR1B1, HNF1B, HGF
32fructose44 1112.6GCK, AKR1B1, SLC2A2, SLC2A4
333-o-methylglucose4411.4GCK, SLC2A4, SLC2A2
34preproinsulin4411.4SLC2A2, PDX1, GCK
35i-app4411.4IAPP, PDX1, GCK
36fatty acid4411.4SLC2A4, ABCC8, LEP, GCK, HGF
37proglucagon4411.4PDX1, SLC2A2, GCK
38glimepiride44 49 1113.3ABCC8, KCNJ11, SLC2A4
39gliclazide44 49 1113.3SLC2A4, KCNJ11, ABCC8
40diazoxide44 59 28 1114.3GCK, KCNJ11, ABCC8
41tolbutamide44 49 28 1114.2ABCC8, GCK, KCNJ11
42cibenzoline4411.1ABCC8, KCNJ11
43aicar44 11 2413.1LEP, GCK, SLC2A4
44norepinephrine44 11 2413.1SLC2A4
45minoxidil44 28 1113.0ABCC8
46[3h]2-deoxyglucose2811.0SLC2A2, SLC2A4
47alloxan4411.0GCK, SLC2A2
48glycerol44 11 2412.9GCK, AKR1B1, LEP, SLC2A4
49forskolin44 49 1112.8PDX1, SLC2A2
50abatacept44 1111.7IL6, CTLA4

GO Terms for genes affiliated with Diabetes Mellitus

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16Gene Ontology
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Biological processes related to Diabetes Mellitus according to GeneCards/GeneDecks:

(show all 22)
idNameGO IDScoreTop Affiliating Genes
1endocrine pancreas developmentGO:03101812.1SLC2A2, GCK, HNF1B, PDX1, NEUROD1, IAPP
2regulation of insulin secretionGO:05079611.9KCNJ11, GCK, NEUROD1, LEP, ABCC8, SLC2A2
3positive regulation of transcription from RNA polymerase II promoterGO:04594411.8HNF1B, HGF, PDX1, NEUROD1, IL6, PLAGL1
4glucose homeostasisGO:04259311.7GCK, PDX1, NEUROD1, WFS1, SLC2A4
5carbohydrate metabolic processGO:00597511.7GCK, AKR1B1, ABCC8, SLC2A4, SLC2A2
6insulin secretionGO:03007311.5HNF1B, PDX1, NEUROD1, LEP
7energy reserve metabolic processGO:00611211.5KCNJ11, LEP, ABCC8, SLC2A2
8positive regulation of insulin secretionGO:03202411.3PDX1, CAPN10, GCK
9hexose transportGO:00864511.3GCK, SLC2A4, SLC2A2
10response to insulin stimulusGO:03286811.3PTPRN, LEP, IL6
11cellular response to insulin stimulusGO:03286911.2GCK, CAPN10, SLC2A4
12positive regulation of apoptotic processGO:04306511.2CAPN10, CTLA4, NEUROD1, IL6
13response to glucose stimulusGO:00974911.2PTPRN, NEUROD1, HNF1B
14glucose transportGO:01575811.2GCK, SLC2A4, SLC2A2
15detection of glucoseGO:05159411.1PDX1, GCK
16positive regulation of STAT protein import into nucleusGO:200036611.1LEP, IL6
17response to drugGO:04249311.1KCNJ11, PDX1, NEUROD1, IL6
18negative regulation of type B pancreatic cell apoptotic processGO:200067511.1WFS1, NEUROD1
19negative regulation of gluconeogenesisGO:04572111.0IL6, GCK
20neurological system processGO:05087710.9WFS1, KCNJ11
21nitric oxide mediated signal transductionGO:00726310.8NEUROD1, PDX1
22glucose metabolic processGO:00600610.7LEP, PDX1, KCNJ11

Molecular functions related to Diabetes Mellitus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1D-glucose transmembrane transporter activityGO:05505610.8SLC2A2, SLC2A4

Products for genes affiliated with Diabetes Mellitus

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Diabetes Mellitus

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet