MCID: DBT082
MIFTS: 17

Diabetes Mellitus, Insulin-Dependent, 12

Categories: Genetic diseases, Metabolic diseases, Rare diseases, Endocrine diseases

Aliases & Classifications for Diabetes Mellitus, Insulin-Dependent, 12

MalaCards integrated aliases for Diabetes Mellitus, Insulin-Dependent, 12:

Name: Diabetes Mellitus, Insulin-Dependent, 12 53 71 28 69
Insulin-Dependent Diabetes Mellitus 12 53 71
Iddm12 53 71

Classifications:



External Ids:

OMIM 53 601388
MedGen 39 C1832392
MeSH 41 D003922
UMLS 69 C1832392

Summaries for Diabetes Mellitus, Insulin-Dependent, 12

UniProtKB/Swiss-Prot : 71 Diabetes mellitus, insulin-dependent, 12: A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical features are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.

MalaCards based summary : Diabetes Mellitus, Insulin-Dependent, 12, also known as insulin-dependent diabetes mellitus 12, is related to type 1 diabetes mellitus 12. An important gene associated with Diabetes Mellitus, Insulin-Dependent, 12 is CTLA4 (Cytotoxic T-Lymphocyte Associated Protein 4). Affiliated tissues include kidney and eye.

Description from OMIM: 601388

Related Diseases for Diabetes Mellitus, Insulin-Dependent, 12

Symptoms & Phenotypes for Diabetes Mellitus, Insulin-Dependent, 12

Clinical features from OMIM:

601388

Drugs & Therapeutics for Diabetes Mellitus, Insulin-Dependent, 12

Search Clinical Trials , NIH Clinical Center for Diabetes Mellitus, Insulin-Dependent, 12

Genetic Tests for Diabetes Mellitus, Insulin-Dependent, 12

Genetic tests related to Diabetes Mellitus, Insulin-Dependent, 12:

# Genetic test Affiliating Genes
1 Diabetes Mellitus, Insulin-Dependent, 12 28 CTLA4

Anatomical Context for Diabetes Mellitus, Insulin-Dependent, 12

MalaCards organs/tissues related to Diabetes Mellitus, Insulin-Dependent, 12:

38
Kidney, Eye

Publications for Diabetes Mellitus, Insulin-Dependent, 12

Articles related to Diabetes Mellitus, Insulin-Dependent, 12:

# Title Authors Year
1
Genetic susceptibility to type 1 diabetes: clinical and molecular heterogeneity of IDDM1 and IDDM12 in a german population. ( 10522814 )
1999
2
Association of CTLA-4 gene A-G polymorphism (IDDM12 locus) with acute-onset and insulin-depleted IDDM as well as autoimmune thyroid disease (Graves' disease and Hashimoto's thyroiditis) in the Japanese population. ( 9421386 )
1998

Variations for Diabetes Mellitus, Insulin-Dependent, 12

Expression for Diabetes Mellitus, Insulin-Dependent, 12

Search GEO for disease gene expression data for Diabetes Mellitus, Insulin-Dependent, 12.

Pathways for Diabetes Mellitus, Insulin-Dependent, 12

GO Terms for Diabetes Mellitus, Insulin-Dependent, 12

Sources for Diabetes Mellitus, Insulin-Dependent, 12

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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