MCID: DBT026
MIFTS: 39

Diabetes Mellitus, Noninsulin-Dependent malady

Genetic diseases (common) category

Summaries for Diabetes Mellitus, Noninsulin-Dependent

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MalaCards based summary: Diabetes Mellitus, Noninsulin-Dependent is related to diabetes mellitus and diabetes mellitus, noninsulin-dependent, with acanthosis nigricans and hypertension. An important gene associated with Diabetes Mellitus, Noninsulin-Dependent is SLC30A8 (solute carrier family 30 (zinc transporter), member 8), and among its related pathways are Growth hormone receptor signaling and IGF1 pathway. The compounds [3h]2-deoxyglucose and repaglinide have been mentioned in the context of this disorder. Related mouse phenotypes are normal and muscle.

Descriptions from OMIM:46 125853,135853

Aliases & Classifications for Diabetes Mellitus, Noninsulin-Dependent

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Diabetes Mellitus, Noninsulin-Dependent, Aliases & Descriptions:

Name: Diabetes Mellitus, Noninsulin-Dependent 46


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Related Diseases for Diabetes Mellitus, Noninsulin-Dependent

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Diseases in the Diabetes Mellitus, Noninsulin-Dependent family:

Kcnj11-Related Susceptibility to Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Noninsulin-Dependent 1
Diabetes Mellitus, Noninsulin-Dependent, Late Onset Diabetes Mellitus, Noninsulin-Dependent, 2

Diseases related to Diabetes Mellitus, Noninsulin-Dependent via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 35)
idRelated DiseaseScoreTop Affiliating Genes
1diabetes mellitus29.5SLC2A2, ABCC8, IGF2BP2, INSR, PAX4, NEUROD1
2diabetes mellitus, noninsulin-dependent, with acanthosis nigricans and hypertension10.6
3diabetes mellitus, noninsulin-dependent, 210.6
4diabetes mellitus, noninsulin-dependent 110.5
5diabetes mellitus, noninsulin-dependent, association with10.5
6diabetes mellitus, noninsulin-dependent, late onset10.5
7familial hyperinsulinism10.4ABCC8
8hyperinsulinemic hypoglycemia10.4ABCC8
9neonatal diabetes mellitus10.4ABCC8, HNF1B, SLC2A2
10polycystic ovary syndrome10.3INSR, IRS1, IRS2
11rectal neoplasm10.3IRS2, IRS1
12maturity-onset diabetes of the young10.3PAX4, NEUROD1, HNF1B, HNF4A
13hyperinsulinism10.2ABCC8, INSR, IRS1, IRS2
14metabolic syndrome x10.2SLC2A2, HNF4A, INSR, ABCC8
15type 1 diabetes mellitus10.2HNF4A, NEUROD1, PAX4, INSR
16liver cancer10.2SLC2A2, HNF4A, HNF1B, IRS1, INSR
17hypertriglyceridemia10.2INSR, IRS1, SLC2A4
18glucose intolerance10.1INSR, PAX4, IRS2, SLC2A4
19pancreatic cancer10.0IRS1, IRS2, AKT2, HNF4A, SLC2A4
20ovarian cancer10.0INSR, AKT2, HNF1B, HNF4A, SLC2A4
21kidney cancer10.0SLC2A4, HNF4A, HNF1B, INSR
22hypoglycemia10.0ABCC8, INSR, HNF4A, GCGR, SLC2A4, SLC2A2
23insulinoma10.0ABCC8, GPD2, INSR, PAX4, HNF4A, SLC2A2
24colorectal cancer10.0PPP1R3A, INSR, IRS1, IRS2, HNF4A
25gestational diabetes10.0ABCC8, INSR, IRS1, IRS2, HNF4A, SLC2A4
26prostate cancer10.0INSR, IRS1, IRS2, AKT2, MAPK8IP1, HNF1B
27liver cirrhosis10.0SLC2A4, IRS1, INSR
28ischemia9.9ABCC8, INSR, MAPK8IP1, SLC2A4
29tongue squamous cell carcinoma9.9INSR, IRS1, IRS2, AKT2, HNF4A, SLC2A4
30adenocarcinoma9.9INSR, NEUROD1, AKT2, HNF1B, HNF4A, SLC2A4
31obesity9.8ABCC8, INSR, IRS1, IRS2, HNF4A, GCGR
32breast cancer9.8INSR, IRS1, IRS2, AKT2, HNF4A, SLC2A4
33hyperglycemia9.6NEUROD1, IRS1, IRS2, HNF1B, HNF4A, GCGR
34insulin resistance9.5AKT2, IRS2, IRS1, PAX4, INSR, ABCC8
35type 2 diabetes mellitus9.3HNF4A, GCGR, SLC2A4, SLC2A2, HNF1B, IRS2

Graphical network of the top 20 diseases related to Diabetes Mellitus, Noninsulin-Dependent:



Diseases related to diabetes mellitus, noninsulin-dependent

Symptoms for Diabetes Mellitus, Noninsulin-Dependent

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Clinical features from OMIM:

125853,135853

Drugs & Therapeutics for Diabetes Mellitus, Noninsulin-Dependent

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Drug clinical trials:

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Genetic Tests for Diabetes Mellitus, Noninsulin-Dependent

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Anatomical Context for Diabetes Mellitus, Noninsulin-Dependent

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Animal Models for Diabetes Mellitus, Noninsulin-Dependent or affiliated genes

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MGI Mouse Phenotypes related to Diabetes Mellitus, Noninsulin-Dependent:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028739.3IRS2, AKT2, HNF4A, GCGR, CDKAL1, PAX4
2MP:00053698.5PPP1R3A, INSR, IRS1, IRS2, AKT2, HNF1B
3MP:00053848.4INSR, NEUROD1, IRS1, IRS2, AKT2, MAPK8IP1
4MP:00053758.4PPP1R3A, GPD2, INSR, IRS1, IRS2, AKT2
5MP:00053708.4GPD2, INSR, IRS1, AKT2, MAPK8IP1, HNF1B
6MP:00107687.7IRS1, NEUROD1, PAX4, INSR, GPD2, IRS2
7MP:00053797.6SLC2A2, ABCC8, GPD2, INSR, PAX4, NEUROD1
8MP:00053787.4IRS1, NEUROD1, PAX4, INSR, GPD2, PPP1R3A
9MP:00053767.4IRS1, NEUROD1, INSR, GPD2, ABCC8, PPP1R3A

Publications for Diabetes Mellitus, Noninsulin-Dependent

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Variations for Diabetes Mellitus, Noninsulin-Dependent

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UniProtKB/Swiss-Prot genetic disease variations for Diabetes Mellitus, Noninsulin-Dependent:

63 (show all 11)
id Symbol AA change Variation ID SNP ID
1AKT2p.Arg274HisVAR_067310
2HNF1Bp.Ser465ArgVAR_017665
3HNF4Ap.Val402IleVAR_004670rs137853337
4INSRp.Arg1191GlnVAR_004098
5INSRp.Thr858AlaVAR_015917rs182552223
6INSRp.Arg1158GlnVAR_015927
7IRS1p.Ser1043TyrVAR_005302
8IRS1p.Cys1095TyrVAR_005303
9MAPK8IP1p.Ser59AsnVAR_012243
10PPP1R3Ap.Ala931GluVAR_019699rs35449651
11SLC2A4p.Val383IleVAR_007170rs121434581

Clinvar genetic disease variations for Diabetes Mellitus, Noninsulin-Dependent:

7 (show all 32)
id Gene Name Type Significance SNP ID Assembly Location
1HNF1BNM_000458.2(HNF1B): c.1395C> G (p.Ser465Arg)single nucleotide variantPathogenicrs121918673GRCh37Chr 17, 36061127: 36061127
2ENPP1ENPP1, IVS20AS, 1-BP DEL, T, -11deletionrisk factor
3ENPP1NM_006208.2(ENPP1): c.517A> C (p.Lys173Gln)single nucleotide variantrisk factorrs1044498GRCh37Chr 6, 132172368: 132172368
4PAX4NM_006193.2(PAX4): c.361C> T (p.Arg121Trp)single nucleotide variantPathogenicrs114202595GRCh37Chr 7, 127254587: 127254587
5AKT2NM_001626.5(AKT2): c.821G> A (p.Arg274His)single nucleotide variantPathogenicrs121434593GRCh37Chr 19, 40743886: 40743886
6SLC30A8NM_173851.2(SLC30A8): c.412C> T (p.Arg138Ter)single nucleotide variantprotectivers200185429GRCh37Chr 8, 118165323: 118165323
7SLC30A8NM_173851.2(SLC30A8): c.101_107delAAGATCA (p.Lys34Serfs)deletionprotectiveGRCh37Chr 8, 118159222: 118159228
8LIPCLIPC, -250G-Asingle nucleotide variantrisk factor
9INSRNM_000208.2(INSR): c.3572G> A (p.Arg1191Gln)single nucleotide variantPathogenicrs121913150GRCh37Chr 19, 7120718: 7120718
10INSRNM_000208.2(INSR): c.3034G> A (p.Val1012Met)single nucleotide variantLikely pathogenic, Pathogenicrs1799816GRCh37Chr 19, 7125518: 7125518
11IL6IL6, -174G-Csingle nucleotide variantrisk factor
12GPD2NM_001083112.2(GPD2): c.1904T> C (p.Phe635Ser)single nucleotide variantPathogenicrs121918407GRCh37Chr 2, 157435621: 157435621
13SLC2A2NM_000340.1(SLC2A2): c.589G> A (p.Val197Ile)single nucleotide variantPathogenicrs121909741GRCh37Chr 3, 170724960: 170724960
14GCGRNM_000160.4(GCGR): c.118G> A (p.Gly40Ser)single nucleotide variantPathogenicrs1801483GRCh37Chr 17, 79767715: 79767715
15IGF2BP2NM_006548.4(IGF2BP2): c.239+29254C> Asingle nucleotide variantrisk factorrs4402960GRCh37Chr 3, 185511687: 185511687
16IRS1IRS1, 3-BP DEL, GLY723deletionPathogenic
17IRS1NM_005544.2(IRS1): c.1823C> G (p.Thr608Arg)single nucleotide variantPathogenicrs104893642GRCh37Chr 2, 227661632: 227661632
18HMGA1HMGA1, 1-BP INS, IVS5, -13insertionrisk factor
19RETNRETN, +62G-Asingle nucleotide variantrisk factor
20CAPN10NM_023083.3(CAPN10): c.471-176G> Asingle nucleotide variantrisk factorrs3792267GRCh37Chr 2, 241531174: 241531174
21CAPN10CAPN10, IVS6, INS/DEL, 39-BPindelrisk factor
22CAPN10CAPN10, IVS13, g.16378G-Tsingle nucleotide variantrisk factor
23CAPN10CAPN10, IVS3, g.4841T-Csingle nucleotide variantrisk factor
24MAPK8IP1NM_005456.3(MAPK8IP1): c.176G> A (p.Ser59Asn)single nucleotide variantPathogenicrs119489103GRCh37Chr 11, 45919710: 45919710
25TCF7L2NM_030756.4(TCF7L2): c.382-41435C> Tsingle nucleotide variantrisk factorrs7903146GRCh37Chr 10, 114758349: 114758349
26TCF7L2NM_030756.4(TCF7L2): c.483+9017G> Tsingle nucleotide variantrisk factorrs12255372GRCh37Chr 10, 114808902: 114808902
27TCF7L2NM_030756.4(TCF7L2): c.483+7162G> Csingle nucleotide variantrisk factorrs11196205GRCh37Chr 10, 114807047: 114807047
28NEUROD1NM_002500.4(NEUROD1): c.332G> T (p.Arg111Leu)single nucleotide variantPathogenicrs104893649GRCh37Chr 2, 182543256: 182543256
29KCNJ11NM_000525.3(KCNJ11): c.67A> G (p.Lys23Glu)single nucleotide variantdrug response, risk factorrs5219GRCh37Chr 11, 17409572: 17409572
30ABCC8NM_001287174.1(ABCC8): c.4138C> T (p.Arg1380Cys)single nucleotide variantPathogenicrs137852673GRCh37Chr 11, 17417462: 17417462
31ABCC8NM_001287174.1(ABCC8): c.1744C> G (p.Leu582Val)single nucleotide variantPathogenicrs137852674GRCh37Chr 11, 17452434: 17452434
32HNF4ANM_000457.4(HNF4A): c.1204G> A (p.Val402Ile)single nucleotide variantPathogenicrs137853337GRCh37Chr 20, 43057049: 43057049

Expression for genes affiliated with Diabetes Mellitus, Noninsulin-Dependent

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Expression patterns in normal tissues for genes affiliated with Diabetes Mellitus, Noninsulin-Dependent

Search GEO for disease gene expression data for Diabetes Mellitus, Noninsulin-Dependent.

Pathways for genes affiliated with Diabetes Mellitus, Noninsulin-Dependent

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Pathways related to Diabetes Mellitus, Noninsulin-Dependent according to GeneCards/GeneDecks:

(show all 34)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.1IRS2, IRS1
210.1IRS2, IRS1
3
Show member pathways
9.9SLC2A2, GCGR, ABCC8
49.9ABCC8, HNF4A, SLC2A2
5
Show member pathways
Development ERBB family signaling59
Development GDNF family signaling59
9.8IRS1, IRS2, AKT2
6
Show member pathways
Immune response IL 4 signaling pathway59
Signal transduction AKT signaling59
9.8IRS1, IRS2, AKT2
79.8SLC2A2, SLC2A4, HNF4A
89.8SLC2A4, IRS2, IRS1
9
Show member pathways
DNA damage response (only ATM dependent)37
Wnt Signaling Pathway and Pluripotency37
9.7AKT2, IRS1, INSR
10
Show member pathways
Insulin Pathway37
9.7AKT2, IRS1, INSR
11
Show member pathways
Prolactin Signaling Pathway37
Development Prolactin receptor signaling59
Leptin signaling pathway37
9.7IRS1, IRS2, AKT2, SLC2A2
12
Show member pathways
9.7INSR, NEUROD1, HNF4A, SLC2A2
13
Show member pathways
9.6PPP1R3A, INSR, AKT2
14
Show member pathways
9.6AKT2, IRS2, IRS1, INSR
15
Show member pathways
9.6AKT2, IRS2, IRS1, INSR
169.5SLC2A4, AKT2, IRS2, IRS1
17
Show member pathways
9.5SLC2A4, AKT2, IRS2, IRS1
189.4INSR, AKT2, HNF4A, SLC2A4
19
Show member pathways
9.3PAX4, NEUROD1, AKT2, HNF1B, HNF4A, SLC2A2
209.3SLC2A4, AKT2, INSR, PPP1R3A
219.3ABCC8, IRS1, IRS2, AKT2, SLC2A4
22
Show member pathways
9.2INSR, IRS1, AKT2, MAPK8IP1, SLC2A4
23
Show member pathways
9.2INSR, IRS1, IRS2, AKT2, MAPK8IP1, HNF4A
24
Show member pathways
PLK2 and PLK4 events37
Polo-like kinase signaling events in the cell cycle37
9.2INSR, IRS1, IRS2, AKT2, SLC2A4
25
Show member pathways
IL-9 Signaling Pathway37
Development Thrombopoietin regulated cell processes59
IL-7 Signaling Pathway37
Immune response IL 9 signaling pathway59
9.2SLC2A4, AKT2, IRS2, IRS1, INSR
26
Show member pathways
9.2INSR, IRS1, IRS2, AKT2, SLC2A4
27
Show member pathways
9.2INSR, IRS1, IRS2, AKT2, SLC2A4
28
Show member pathways
9.1SLC2A4, IRS2, IRS1, INSR, PPP1R3A
29
Show member pathways
8.9PAX4, NEUROD1, AKT2, HNF1B, HNF4A, SLC2A4
30
Show member pathways
8.9PPP1R3A, INSR, IRS1, IRS2, AKT2, MAPK8IP1
318.9PPP1R3A, INSR, IRS1, IRS2, AKT2, SLC2A4
32
Show member pathways
Transcription Receptor mediated HIF regulation59
Development CNTF receptor signaling59
Class IB PI3K non-lipid kinase events37
ErbB2/ErbB3 signaling events37
Development Growth hormone signaling via PI3K AKT and MAPK cascades59
Translation Regulation activity of EIF259
Regulation of lipid metabolism Insulin signaling generic cascades59
Transcription PPAR Pathway59
Cell adhesion PLAU signaling59
Translation Regulation activity of EIF4F59
8.9PPP1R3A, INSR, IRS1, IRS2, AKT2, SLC2A4
338.8INSR, NEUROD1, IRS1, IRS2, AKT2, HNF4A
34
Show member pathways
8.6SLC2A2, ABCC8, INSR, NEUROD1, IRS1, IRS2

Compounds for genes affiliated with Diabetes Mellitus, Noninsulin-Dependent

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Compounds related to Diabetes Mellitus, Noninsulin-Dependent according to GeneCards/GeneDecks:

(show top 50)    (show all 66)
idCompoundScoreTop Affiliating Genes
1[3h]2-deoxyglucose2910.3SLC2A4, SLC2A2
2repaglinide50 44 1212.2ABCC8, PAX4, NEUROD1
3vanadyl sulfate4410.1INSR, IRS1
43-o-methylglucose4410.1SLC2A2, INSR, SLC2A4
5c-peptide4410.1IRS1, HNF4A, SLC2A2, INSR
6fructose44 1211.1SLC2A2, GCGR, SLC2A4
7vanadium4410.1SLC2A4, INSR, IRS1
8phosphoenolpyruvate44 1211.1SLC2A4, HNF4A, IRS1, SLC2A2
9preproinsulin4410.1SLC2A2, INSR
10gliclazide44 50 1212.0ABCC8, INSR, SLC2A4
11glimepiride44 50 1212.0ABCC8, SLC2A4, INSR
12sulfonylurea4410.0ABCC8, IRS1, SLC2A4, SLC2A2
13phenylarsine oxide4410.0INSR, IRS1, SLC2A4
14streptozotocin449.9IRS1, INSR, SLC2A4, SLC2A2
15glucosamine44 25 1211.9IRS1, SLC2A4, INSR, IRS2
16palmitate449.9IRS1, HNF4A, SLC2A4, INSR
17sterol449.9SLC2A2, SLC2A4, IRS2, IRS1, HNF4A
18anisomycin44 1210.9INSR, IRS1, SLC2A4, IRS2
19okadaic acid44 6010.9SLC2A4, HNF4A, IRS2, IRS1
20ibmx44 60 2911.8SLC2A2, INSR, IRS1, SLC2A4
21glibenclamide44 29 50 6012.8ABCC8, INSR, SLC2A4
22phosphatidylinositol-3,4,5-trisphosphate44 2510.8INSR, IRS2, SLC2A4, IRS1
23rosiglitazone29 44 50 25 1213.8SLC2A4, INSR, IRS1, IRS2
24troglitazone44 29 60 1212.8SLC2A4, IRS2, IRS1, INSR
25pyruvate449.8SLC2A2, GPD2, HNF4A, SLC2A4
26glycerol44 25 1211.8SLC2A4, HNF4A, INSR, IRS1
27pioglitazone29 44 50 1212.8IRS1, SLC2A4, INSR
28oligonucleotide449.8IRS2, SLC2A2, HNF1B, HNF4A, GCGR, AKT2
29grp-1449.7SLC2A4, INSR
30phosphotyrosine449.7INSR, IRS1, IRS2, MAPK8IP1, SLC2A4
31pd 98,059449.7INSR, IRS1, IRS2, SLC2A4, HNF4A
32metformin44 50 1211.7IRS2, ABCC8, IRS1, SLC2A4, INSR
332-deoxyglucose44 1210.6SLC2A4, IRS1, PPP1R3A, SLC2A2, INSR
34fatty acid449.6GCGR, HNF4A, IRS2, IRS1, ABCC8, SLC2A4
35arginine449.6HNF1B, IRS1, SLC2A2, HNF4A, INSR, ABCC8
36rapamycin449.6IRS2, INSR, AKT2, SLC2A4, IRS1
37sb 20358044 6010.6IRS1, INSR, AKT2, SLC2A4
38ly294002449.6IRS1, AKT2, IRS2, INSR, SLC2A4
39wortmannin449.6SLC2A4, IRS2, AKT2, IRS1, INSR
40tamoxifen44 50 29 1212.6SLC2A4, AKT2, IRS2, IRS1
41retinoic acid44 2510.4NEUROD1, IRS2, IRS1, HNF4A, SLC2A4, HNF1B
42h2o2449.4IRS1, GPD2, SLC2A4, SLC2A2, INSR
43phosphatidylinositol449.4INSR, IRS1, IRS2, AKT2, HNF4A, SLC2A4
44threonine449.3AKT2, MAPK8IP1, IRS2, HNF4A, INSR, IRS1
45testosterone44 60 25 1212.3ABCC8, IRS1, INSR, HNF4A, SLC2A4
46serine449.0AKT2, MAPK8IP1, IRS2, ABCC8, HNF4A, SLC2A4
47lipid448.7AKT2, IRS2, SLC2A4, HNF4A, LIPH, IRS1
48glycogen44 259.6IRS2, INSR, GCGR, PPP1R3A, ABCC8, IRS1
49tyrosine448.5HNF4A, AKT2, IRS2, IRS1, INSR, ABCC8
50glucose447.5SLC2A2, PPP1R3A, ABCC8, GPD2, INSR, PAX4

GO Terms for genes affiliated with Diabetes Mellitus, Noninsulin-Dependent

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Cellular components related to Diabetes Mellitus, Noninsulin-Dependent according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1insulin receptor complexGO:0058999.7IRS1, INSR
2plasma membraneGO:0058868.5INSR, LIPH, IRS1, IRS2, AKT2, GCGR

Biological processes related to Diabetes Mellitus, Noninsulin-Dependent according to GeneCards/GeneDecks:

(show all 22)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of plasma membrane long-chain fatty acid transportGO:01074810.3AKT2, IRS2
2positive regulation of glucose import in response to insulin stimulusGO:200127510.3IRS1, AKT2
3regulation of cell cycle arrestGO:07115610.2NEUROD1, AKT2
4lipid homeostasisGO:05508810.2HNF4A, IRS2
5regulation of lipid metabolic processGO:01921610.2IRS2, HNF4A
6positive regulation of glucose metabolic processGO:01090710.2AKT2, IRS2, IRS1
7energy reserve metabolic processGO:00611210.1SLC2A2, GCGR, ABCC8
8positive regulation of fatty acid beta-oxidationGO:03200010.1IRS1, IRS2, AKT2
9signal transduction involved in regulation of gene expressionGO:02301910.1HNF4A, NEUROD1
10response to glucoseGO:00974910.1HNF4A, HNF1B, IRS2, NEUROD1
11regulation of insulin secretionGO:05079610.0ABCC8, NEUROD1, HNF4A, SLC2A2
12positive regulation of cell differentiationGO:04559710.0NEUROD1, PAX4
13mammary gland developmentGO:03087910.0IRS2, IRS1
14positive regulation of cell migrationGO:03033510.0IRS2, IRS1, INSR
15positive regulation of glycogen biosynthetic processGO:0457259.9AKT2, IRS2, IRS1, INSR
16endocrine pancreas developmentGO:0310189.9PAX4, NEUROD1, HNF1B, HNF4A, SLC2A2
17positive regulation of glucose importGO:0463269.9INSR, IRS1, IRS2, AKT2
18insulin receptor signaling pathwayGO:0082869.8INSR, IRS1, IRS2, AKT2
19JAK-STAT cascade involved in growth hormone signaling pathwayGO:0603979.8IRS2, IRS1
20carbohydrate metabolic processGO:0059759.6ABCC8, INSR, SLC2A4, SLC2A2
21cellular response to insulin stimulusGO:0328699.5INSR, IRS1, IRS2, AKT2, SLC2A4
22glucose homeostasisGO:0425939.5SLC2A4, GCGR, HNF4A, IRS1, NEUROD1, INSR

Molecular functions related to Diabetes Mellitus, Noninsulin-Dependent according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1insulin receptor bindingGO:00515810.1IRS2, IRS1
2D-glucose transmembrane transporter activityGO:05505610.0SLC2A2, SLC2A4
3insulin-like growth factor receptor bindingGO:0051599.9INSR, IRS1
4phosphatidylinositol 3-kinase bindingGO:0435489.9IRS2, IRS1, INSR
5sequence-specific DNA bindingGO:0435659.4HNF4A, HNF1B, NEUROD1, PAX4

Products for genes affiliated with Diabetes Mellitus, Noninsulin-Dependent

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
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51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet