MCID: DBT064
MIFTS: 37

Diabetes Mellitus, Transient Neonatal, 1 malady

Categories: Genetic diseases, Rare diseases, Endocrine diseases, Metabolic diseases, Fetal diseases

Aliases & Classifications for Diabetes Mellitus, Transient Neonatal, 1

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Aliases & Descriptions for Diabetes Mellitus, Transient Neonatal, 1:

Name: Diabetes Mellitus, Transient Neonatal, 1 49 11 65
Transient Neonatal Diabetes Mellitus 10 45 12 51 65
Transient Neonatal Diabetes Mellitus 1 67 24
Diabetes Mellitus, Transient Neonatal 49 45
Tndm1 45 67
 
Tndm 45 51
Chromosome 6-Associated Transient Diabetes Mellitus 45
Diabetes Mellitus, 6q24-Related Transient Neonatal 45
Dmtn 45

Characteristics:

Orphanet epidemiological data:

51
transient neonatal diabetes mellitus:
Inheritance: Autosomal dominant,Autosomal recessive,Not applicable; Prevalence: 1-9/1000000 (Europe); Age of onset: Antenatal,Neonatal

Classifications:



External Ids:

OMIM49 601410
Disease Ontology10 DOID:0060334
ICD1027 P70.2
Orphanet51 99886
ICD10 via Orphanet28 P70.2
MedGen34 C1832386
UMLS65 C0342273, C1832386

Summaries for Diabetes Mellitus, Transient Neonatal, 1

About this section
OMIM:49 Neonatal diabetes mellitus (NDM), defined as insulin-requiring hyperglycemia within the first month of life, is a rare... (601410) more...

MalaCards based summary: Diabetes Mellitus, Transient Neonatal, 1, also known as transient neonatal diabetes mellitus, is related to diabetes mellitus, transient neonatal, 3 and diabetes mellitus, transient neonatal 2, and has symptoms including transient neonatal diabetes mellitus, hyperglycemia and dehydration. An important gene associated with Diabetes Mellitus, Transient Neonatal, 1 is ZFP57 (ZFP57 Zinc Finger Protein), and among its related pathways are Type II diabetes mellitus and FOXA2 and FOXA3 transcription factor networks. Related mouse phenotypes are no phenotypic analysis and endocrine/exocrine gland.

Disease Ontology:10 A neonatal diabetes mellitus characterized by hyperglycemia during the neonatal period that remits during infancy but recurs in later life in most patients.

NIH Rare Diseases:45 Transient neonatal diabetes mellitus (tndb) is a type of diabetes that appears within the first few weeks of life but is transient; affected infants go into remission within a few months, with possible relapse to permanent diabetes in adolescence or adulthood. affected individuals have slow growth before birth followed by hyperglycemia, dehydration and failure to thrive in infancy. approximately 70% of cases are caused by the overactivity of certain genes in a region of the long (q) arm of chromosome 6 called 6q24. these cases are referred to as 6q24-related tndb; most (but not all) of these cases are not inherited. other genetic causes include mutations in the kcnj11 and abcc8 genes, which usually cause permanent neonatal diabetes. treatment may include rehydration and intravenous insulin at the time of diagnosis, followed by subcutaneous insulin. last updated: 8/28/2012

UniProtKB/Swiss-Prot:67 Transient neonatal diabetes mellitus 1: Neonatal diabetes is a form of diabetes mellitus defined by the onset of mild-to-severe hyperglycemia within the first months of life. In about half of the neonates, diabetes is transient and resolves at a median age of 3 months, whereas the rest have a permanent form of diabetes.

Related Diseases for Diabetes Mellitus, Transient Neonatal, 1

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Diseases in the Neonatal Diabetes Mellitus family:

diabetes mellitus, transient neonatal, 1 Diabetes Mellitus, Transient Neonatal 2
Diabetes Mellitus, Transient Neonatal, 3 Diabetes Mellitus, 6q24-Related Transient Neonatal
Abcc8-Related Transient Neonatal Diabetes Mellitus 2 Diabetes Mellitus, Kcnj11-Related Transient Neonatal

Diseases related to Diabetes Mellitus, Transient Neonatal, 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
idRelated DiseaseScoreTop Affiliating Genes
1diabetes mellitus, transient neonatal, 334.7ABCC8, KCNJ11
2diabetes mellitus, transient neonatal 212.7
3abcc8-related transient neonatal diabetes mellitus 212.7
4diabetes mellitus, 6q24-related transient neonatal11.7
5prostate cancer11.7
6malaria11.6
7hypotrichosis11.6
8hereditary spherocytosis11.5
9neuroblastoma10.5
10maturity-onset diabetes of the young, type 1310.4ABCC8, KCNJ11
11usher syndrome, type 1c10.4ABCC8, KCNJ11
12aphasia10.4ABCC8, KCNJ11
13sparse hair-short stature-skin anomalies syndrome10.4ABCC8, KCNJ11
14conversion disorder10.4ABCC8, KCNJ11
15maternal uniparental disomy of chromosome 2210.3HYMAI, PLAGL1, TNDM
16disorders of intracellular cobalamin metabolism10.3HYMAI, PLAGL1, ZFP57
17dengue disease10.3
18dengue hemorrhagic fever10.3
19monomelic amyotrophy10.3ABCC8, INS, KCNJ11
20acute insulin response10.3ABCC8, INS, KCNJ11
21diaphanospondylodysostosis10.3ABCC8, INS, KCNJ11
22chronic follicular conjunctivitis10.2ABCC8, INS, KCNJ11
23perlman syndrome10.2ABCC8, KCNJ11
24hyperglycemia10.2ABCC8, INS, KCNJ11
25placental choriocarcinoma10.2ABCC8, INS, KCNJ11
26epithelioid trophoblastic tumor10.2KHDC3L, NLRP2
27femoral neuropathy10.2ABCC8, INS, KCNJ11
28nephrolithiasis/osteoporosis, hypophosphatemic, 110.1ABCC8, NLRP2, PLAGL1, ZFP57
29fragile x-associated tremor/ataxia syndrome10.1ABCC8, INS, KCNJ11, PTF1A
30nonphotosensitive trichothiodystrophy10.1ABCC8, INS, KCNJ11
31testicular germ cell tumor non-seminomatous10.1KHDC3L, NLRP2
32aromatic l-amino acid decarboxylase deficiency10.1GRB10, UROD, ZFP57
33transmitted_by9.9ABCC8, INS, KCNJ11
34antidepressant type abuse9.8ABCC8, INS, KCNJ11, PLAGL1, PTF1A, ZFP57
35nephronophthisis 196.6ABCC8, DNMT3L, EIF2AK3, FKBP6, GRB10, HYMAI

Graphical network of the top 20 diseases related to Diabetes Mellitus, Transient Neonatal, 1:



Diseases related to diabetes mellitus, transient neonatal, 1

Symptoms for Diabetes Mellitus, Transient Neonatal, 1

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Symptoms by clinical synopsis from OMIM:

601410

Clinical features from OMIM:

601410

HPO human phenotypes related to Diabetes Mellitus, Transient Neonatal, 1:

id Description Frequency HPO Source Accession
1 transient neonatal diabetes mellitus HP:0008255
2 hyperglycemia HP:0003074
3 dehydration HP:0001944
4 severe failure to thrive HP:0001525
5 intrauterine growth retardation HP:0001511

Drugs & Therapeutics for Diabetes Mellitus, Transient Neonatal, 1

About this section

Drugs for Diabetes Mellitus, Transient Neonatal, 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MisoprostolapprovedPhase 426559122-46-25282381
Synonyms:
(+/-)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1 methyl ester
(11-alpha,13E)-(+-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester
59122-46-2
62015-39-8
AC1NQZZA
Ambap103601-27-0
Arthrotec
BRN 4155643
CCRIS 6859
CHEMBL606
CID5282381
Cytotec
Cytotec (TN)
D00419
DB00929
GyMiso
HMS2090L10
HSDB 3573
I14-11712
Isprelor
 
M6807_SIGMA
MLS000028863
Methyl (+-)-11-alpha,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
Misopess
Misoprostol
Misoprostol (JAN/USAN/INN)
Misoprostolum
Misoprostolum [INN-Latin]
Misotol
MolPort-003-666-830
NCGC00162445-01
NCGC00162445-02
SC 29333
SC-29333
SMP1_000193
SMR000058558
UNII-0E43V0BB57
XP-16J
methyl (11alpha,13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoate
misoprostol
2AntacidsPhase 41453
3Gastrointestinal AgentsPhase 46401
4Anti-Ulcer AgentsPhase 41453
5
ProgesteroneapprovedPhase 350057-83-05994
Synonyms:
(S)-4-Pregnene-3,20-dione
(S)-Pregn-4-en-3,20-dione
(S)-Progesterone
.beta.-Progesterone
.delta.(sup4)-Pregnene-3,20-dione
.delta.4-Pregnene-3,20-dione
17.alpha.-Progesterone
17a-Progesterone
17alpha-Progesterone
17alpha-progesterone
17α-progesterone
1dbb
1h60
257630-50-5
3,20-Pregnene-4
32104FB6-BF81-4F6E-83C2-024DEEAEB272
4-Pregnen-3,20-dione
4-Pregnene-3,20-dione
46665_FLUKA
46665_RIEDEL
57-83-0
753497-20-0
8012-32-6
8023-13-0
AC-700
AC1L1LKF
AI3-51682
Agolutin
Akrolutin
BB_NC-0185
BHR-100
BIDD:ER0547
BIDD:PXR0094
BPBio1_000676
BRD-K64994968-001-03-6
BSPBio_000614
Bio-luton
C00410
CCRIS 533
CHEBI:17026
CHEMBL103
CID5994
CIDR
CMC_13406
COL-1620
CPD000058345
Colprosterone
Corlutin
Corlutina
Corluvite
Corporin
Corpus Luteum Hormone
Corpus luteum hormone
Crinone
Crinone (TN)
Crinone progesterone gel
Curretab
Cyclogest
Cyclogesterin
D00066
D4-Pregnene-3,20-dione
DB00396
DR-2011
Delalutin
Delta(4)-pregnene-3,20-dione
Duraprogen
EINECS 200-350-6
ETI-411
EU-0100895
Endometrin
Estima
FE-999913
Flavolutan
Fologenon
Gelbkoerperhormon
Gesterol
Gesterol 100
Gesterol 50
Gestiron
Gestone
Gestormone
Gestron
Glanducorpin
Gynlutin
Gynoluton
Gynolutone
HMS1569O16
HMS2051O05
HMS2090J07
HSDB 3389
Hormoflaveine
Hormoluton
Hydroxyprogesterone Caproate
Hydroxyprogesterone Caproic acid
LMST02030159
LS-234
Lingusorbs
Lipo-Lutin
Lipolutin
Lopac0_000895
Lucorteum
Lucorteum Sol
Lucorteum sol
Lugesteron
Luteal hormone
Luteinique
Luteocrin normale
Luteodyn
Luteogan
Luteohormone
Luteol
Luteol (VAN)
Luteopur
Luteosan
Luteostab
Luteovis
Luteum
Lutex
Lutidon
Lutin
Lutinus
Lutociclina
Lutocuclin M
Lutocyclin
Lutocyclin M
 
Lutocyclin m
Lutocylin
Lutocylol
Lutoform
Lutogyl
Lutogynon
Lutren
Lutromone
MLS000028517
MLS000758277
MLS001074187
MLS002222367
MPA
Membrettes
Methylpregnone
Micronized Progesterone
MolPort-001-794-643
NCGC00022185-03
NCGC00022185-04
NCGC00022185-05
NCGC00022185-06
NCGC00022185-07
NCGC00022185-08
NCGC00022185-09
NCGC00090798-01
NCGC00090798-02
NCI60_042166
NSC 64377
NSC 9704
NSC-9704
NSC64377
NSC9704
Nalutron
Natural Progesterone
P 0130
P0130_SIGMA
P0478
P3972_SIGMA
P6149_SIGMA
P7556_ALDRICH
P7556_SIGMA
P8783_SIGMA
P9776_SIGMA
PROGESTERONE
Percutacrine
Percutacrine Luteinique
Piaponon
Pranone
Pregn-4-en-3,20-dione
Pregn-4-ene-3,20-dione
Pregnene-3,20-dione
Pregnenedione
Prestwick0_000477
Prestwick1_000477
Prestwick2_000477
Prestwick3_000477
Prestwick_411
Primolut
Prochieve
Progeffik
Progekan
Progestan
Progestasert
Progesterol
Progesteron
Progesterona
Progesterona [INN-Spanish]
Progesterone
Progesterone (JP15/USP/INN)
Progesterone [INN:BAN:JAN]
Progesterone [Progestins]
Progesterone, water-soluble
Progesterone-Water Soluble
Progesterone: HBC complex
Progesteronum
Progesteronum [INN-Latin]
Progestin
Progestogel
Progestol
Progeston
Progestone
Progestosol
Progestrel
Progestron
Progestronol
Progestérone
Projestaject
Prolets
Prolidon
Prolutin
Proluton
Prolutone
Prometrium
Prometrium (TN)
Prontogest
Protormone
S00293
S1705_Selleck
SAM001247039
SMR000058345
SMR000653542
SPBio_002553
SR-01000000088
SR-01000000088-5
Spectrum5_002053
Syngesterone
Syngestrets
Synovex S
Syntolutan
U 3672
UNII-4G7DS2Q64Y
Utrogest
Utrogestan
Vitarrine
WLN: L E5 B666 OV MUTJ A1 E1 FV1
ZINC04428529
beta-Progesterone
bmse000482
component of Cyclogesterin
corpus luteum hormone
delta(4)-Pregnene-3,20-dione
delta(Sup 4)-Pregnene-3,20-dione
delta(Sup4)-pregnene-3,20-dione
delta(sup 4)-Pregnene-3,20-dione
delta4-Pregnene-3,20-dione
luteohormone
nchembio.2007.53-comp14
6
DiazoxideapprovedPhase 2, Phase 321364-98-73019
Synonyms:
2H-1,2, 4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
364-98-7
7-Chloro-3-methyl-1lambda~4~,2,4-benzothiadiazin-1-ol 1-oxide
7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido [Italian]
7-chloro-3-methyl-4H-1
AC1L1EZN
Aroglycem
BPBio1_000016
BRD-K73109821-001-05-2
BSPBio_000014
BSPBio_001307
BSPBio_002290
Bio1_000036
Bio1_000525
Bio1_001014
Bio2_000027
Bio2_000507
C06949
C8H7ClN2O2S
CAS-364-98-7
CBiol_001750
CHEBI:4495
CHEMBL181
CID3019
CPD000058392
D 9035
D00294
D003981
D9035_SIGMA
DB01119
Diazossido
Diazossido [DCIT]
Diazossido [Italian]
Diazoxide
Diazoxide (JAN/USP/INN)
Diazoxide [USAN:INN:BAN]
Diazoxido
Diazoxido [INN-Spanish]
Diazoxidum
Diazoxidum [INN-Latin]
Dizoxide
EINECS 206-668-1
EU-0100404
Eudemine
HMS1361B09
HMS1568A16
HMS1791B09
HMS1922L22
HMS1989B09
HMS2051P20
HMS2089L04
HMS2093N12
Hyperstat
Hyperstat (TN)
Hypertonalum
I06-2041
 
IDI1_033777
KBio2_000027
KBio2_002595
KBio2_005163
KBio3_000053
KBio3_000054
KBio3_001510
KBioGR_000027
KBioGR_001776
KBioSS_000027
LS-40410
Lopac-D-9035
Lopac0_000404
MLS000028459
MLS001076071
MolPort-003-666-772
MolPort-003-941-186
Mutabase
NCGC00015380-01
NCGC00015380-02
NCGC00015380-03
NCGC00015380-05
NCGC00015380-12
NCGC00024907-01
NCGC00024907-02
NCGC00024907-03
NCGC00024907-04
NCGC00024907-05
NCGC00024907-06
NCGC00024907-07
NCGC00024907-08
NSC 64198
NSC 76130
NSC-64198
NSC64198
NSC76130
Prestwick0_000087
Prestwick1_000087
Prestwick2_000087
Prestwick3_000087
Prestwick_163
Proglicem
Proglycem
SAM001246872
SMR000058392
SPBio_001953
SPECTRUM2300206
SRG 95213
SRG-95213
Sch 6783
Sch-6783
Spectrum3_000735
Spectrum4_001248
Tocris-0964
UNII-O5CB12L4FN
VU0239714-6
ZINC03872277
diazoxide
nchembio.150-comp49
nchembio.476-comp10
7Hormone AntagonistsPhase 310002
8Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 39988
9ProgestinsPhase 3433
10HormonesPhase 311748
11EstrogensPhase 32144
1217-alpha-hydroxy-progesterone caproatePhase 326
1311-hydroxyprogesteronePhase 326
14Estrogen AntagonistsPhase 31155
15Vasodilator AgentsPhase 2, Phase 32926
16Hypoglycemic AgentsPhase 2, Phase 34503
17Antihypertensive AgentsPhase 2, Phase 33618
18CaproateNutraceuticalPhase 330
19
Oxytocinapproved36650-56-6439302, 53477758
Synonyms:
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
(Arg8)-Vasopressin
(Arg8)-Vasotocin
1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide
50-56-6
AC1L9735
Argipressin
Argpressin Acetate
BCBcMAP01_000094
Biotinyl-(Arg8)-Vasopressin
C00746
CHEBI:492195
CHEBI:7872
CHEMBL395429
CID439302
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2
D00089
Disulfide bridge Cys1-Cys6
Gly-Leu-Pro-c
HS-2021
L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide
MolPort-003-938-941
 
NCGC00167132-01
O3251_SIGMA
O4375_SIGMA
OXT
OXYTOCIN
Ocytocin
Oxitocina
Oxytocic hormone
Oxytocin
Oxytocin (JP15/USP/INN)
Oxytocin (TN)
Oxytocin 10 Usp Units In Dextrose 5%
Oxytocin 20 Usp Units In Dextrose 5%
Oxytocin 5 Usp Units In Dextrose 5%
Oxytocin Acetate
Oxytocin injection
Oxytocine
Oxytocinum
Pitocin
Pitocin (TN)
SID29217903
SID50111741
Syntocinon
Syntocinon (TN)
TI-001
alpha-Hypophamine
nchembio.184-comp2
20
Dinoprostoneapproved74363-24-65280360
Synonyms:
(-)-Prostaglandin E2
(15S)-Prostaglandin E2
(15S)-Prostaglandin e2
(5Z,11-alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11.alpha.,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic
(5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid
(5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11alpha,13e,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoic acid
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate
(5Z,13E,15S)-11-alpha,15-dihydroxy-9-oxoprost-5,13-dienoate
(5Z,13E,15S)-11-alpha,15-dihydroxy-9-oxoprost-5,13-dienoic acid
(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,13e)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate
(5Z,13e)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate
(E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid
(Z)-7-((1R,2R,3R)-3-Hydroxy-2-((S,e)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid
(Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
(e,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid
05D31BD5-818B-4A92-8CFC-BEC19926A5B3
363-24-6
5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)- (8CI)
5-trans-PGE2
7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
AC-6098
AC1NQWXW
BML1-F07
BMS-279654 & PGE2
BRD-K26521938-001-04-9
BSPBio_001490
C00584
CHEBI:15551
CHEMBL548
CID5280360
Cervidil
Cervidil (TN)
D00079
D015232
DB00917
Dinoproston
Dinoprostona
Dinoprostona [INN-Spanish]
Dinoprostone
Dinoprostone (JAN/USP/INN)
Dinoprostone Prostaglandin E2
Dinoprostone [USAN:INN:BAN:JAN]
Dinoprostone beta-Cyclodextrin Clathrate
Dinoprostonum
Dinoprostonum [INN-Latin]
E2 alpha, Prostaglandin
E2, Prostaglandin
E2alpha, Prostaglandin
 
EINECS 206-656-6
Gel, Prepidil
Glandin
HMS1361K12
HMS1791K12
HMS1989K12
HMS2089D17
IDI1_033960
L-Prostaglandin E2
LMFA03010003
LS-125823
Minprositin E2
Minprostin E2
MolPort-003-939-184
NCGC00092361-01
NCGC00092361-02
NCGC00092361-03
NCGC00092361-04
NCGC00092361-05
NSC 165560
NSC 196514
P0409_SIGMA
P5640_SIGMA
P6532_SIGMA
PGE2
PGE2 alpha
PGE2alpha
Prepidil
Prepidil (TN)
Prepidil Gel
Prestwick_793
Propess
Prostaglandin E
Prostaglandin E2
Prostaglandin E2 alpha
Prostaglandin E2alpha
Prostarmon E
Prostarmon E2
Prostenon
Prostin
Prostin E
Prostin E2
Prostin E2 (TN)
Prostin e2
SMP2_000056
ST50826265
U 12062
U-12062
UNII-K7Q1JQR04M
[3H]PGE2
alpha, PGE2
alpha, Prostaglandin E2
l-7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
l-PGE2
l-Prostaglandin E2
nchembio.106-comp6
nchembio.147-comp12
21AstragalusNutraceutical48

Interventional clinical trials:

idNameStatusNCT IDPhase
1Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness TrialRecruitingNCT02639429Phase 4
2Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)CompletedNCT00099164Phase 3
3Diazoxide In the Management Of Hypoglycemic NeonatesNot yet recruitingNCT00994149Phase 2, Phase 3
4Gestational Diabetes: Induction Versus Expectant Management of LabourCompletedNCT01058772
5Genetic Disease Gene IdentificationEnrolling by invitationNCT00916903

Search NIH Clinical Center for Diabetes Mellitus, Transient Neonatal, 1

Genetic Tests for Diabetes Mellitus, Transient Neonatal, 1

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Anatomical Context for Diabetes Mellitus, Transient Neonatal, 1

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Animal Models for Diabetes Mellitus, Transient Neonatal, 1 or affiliated genes

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MGI Mouse Phenotypes related to Diabetes Mellitus, Transient Neonatal, 1:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030127.6ABCC8, EIF2AK3, FKBP6, INS, KCNJ11, PLAGL1
2MP:00053796.9ABCC8, DNMT3L, EIF2AK3, FKBP6, GRB10, INS

Publications for Diabetes Mellitus, Transient Neonatal, 1

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Variations for Diabetes Mellitus, Transient Neonatal, 1

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UniProtKB/Swiss-Prot genetic disease variations for Diabetes Mellitus, Transient Neonatal, 1:

67
id Symbol AA change Variation ID SNP ID
1ZFP57p.Arg166HisVAR_054771
2ZFP57p.His193AsnVAR_054772
3ZFP57p.His374AspVAR_054773

Clinvar genetic disease variations for Diabetes Mellitus, Transient Neonatal, 1:

5
id Gene Variation Type Significance SNP ID Assembly Location
1ZFP57NM_001109809.2(ZFP57): c.783C> A (p.Cys261Ter)single nucleotide variantPathogenicrs61730328GRCh37Chr 6, 29641105: 29641105
2ZFP57NM_001109809.2(ZFP57): c.317_318delAG (p.Glu106Valfs)deletionPathogenicrs606231121GRCh38Chr 6, 29675420: 29675421
3ZFP57NM_001109809.2(ZFP57): c.1383delC (p.Tyr462Ilefs)deletionPathogenicrs606231122GRCh38Chr 6, 29672728: 29672728
4ZFP57NM_001109809.2(ZFP57): c.1372C> G (p.His458Asp)single nucleotide variantPathogenicrs79020217GRCh37Chr 6, 29640516: 29640516
5ZFP57NM_001109809.2(ZFP57): c.743G> A (p.Arg248His)single nucleotide variantPathogenicrs77625743GRCh37Chr 6, 29641145: 29641145
6ZFP57NM_001109809.2(ZFP57): c.829C> A (p.His277Asn)single nucleotide variantPathogenicrs78378398GRCh37Chr 6, 29641059: 29641059
7ZFP57NM_001109809.2(ZFP57): c.898_905delACCCAGGC (p.Thr300Terfs)deletionPathogenicrs606231123GRCh38Chr 6, 29673206: 29673213

Expression for genes affiliated with Diabetes Mellitus, Transient Neonatal, 1

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Search GEO for disease gene expression data for Diabetes Mellitus, Transient Neonatal, 1.

Pathways for genes affiliated with Diabetes Mellitus, Transient Neonatal, 1

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Pathways related to Diabetes Mellitus, Transient Neonatal, 1 according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.7ABCC8, INS, KCNJ11
29.7ABCC8, INS, KCNJ11

GO Terms for genes affiliated with Diabetes Mellitus, Transient Neonatal, 1

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Biological processes related to Diabetes Mellitus, Transient Neonatal, 1 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of protein localization to nucleusGO:19001829.3EIF2AK3, INS
2endocrine pancreas developmentGO:00310189.3EIF2AK3, INS, PTF1A

Molecular functions related to Diabetes Mellitus, Transient Neonatal, 1 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ATP-activated inward rectifier potassium channel activityGO:001527210.0ABCC8, KCNJ11

Sources for Diabetes Mellitus, Transient Neonatal, 1

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet