MCID: DBT031
MIFTS: 32

Diabetes, Type 2 malady

Summaries for Diabetes, Type 2

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33MedlinePlus, 63Wikipedia, 46OMIM, 32MalaCards
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MedlinePlus:33 Diabetes means your blood glucose, or blood sugar, levels are too high. with type 2 diabetes, the more common type, your body does not make or use insulin well. insulin is a hormone that helps glucose get into your cells to give them energy. without insulin, too much glucose stays in your blood. over time, high blood glucose can lead to serious problems with your heart, eyes, kidneys, nerves, and gums and teeth. you have a higher risk of type 2 diabetes if you are older, obese, have a family history of diabetes, or do not exercise. the symptoms of type 2 diabetes appear slowly. some people do not notice symptoms at all. the symptoms can include being very thirsty urinating often feeling very hungry or tired losing weight without trying having sores that heal slowly having blurry eyesight a blood test can show if you have diabetes. many people can manage their diabetes through healthy eating, physical activity, and blood glucose testing. some people also need to take diabetes medicines. nih: national institute of diabetes and digestive and kidney diseases

MalaCards: Diabetes, Type 2, also known as diabetes mellitus, non-insulin-dependent, is related to type 2 diabetes mellitus and diabetes mellitus. An important gene associated with Diabetes, Type 2 is GPD2 (glycerol-3-phosphate dehydrogenase 2 (mitochondrial)). The drugs insulin and insulin, aspart, human and the compound glycerol 3-phosphate have been mentioned in the context of this disorder. Affiliated tissues include eye, heart and kidney, and related mouse phenotype adipose tissue.

Wikipedia:63 Diabetes mellitus type more...

Description from OMIM:46 125853

Aliases & Classifications for Diabetes, Type 2

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46OMIM, 60UMLS, 33MedlinePlus
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Aliases & Descriptions:

diabetes, type 2 46
diabetes mellitus, non-insulin-dependent 60
diabetes type 2 33


Related Diseases for Diabetes, Type 2

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Diabetes, Type 2:



Diseases related to diabetes, type 2

Clinical Features for Diabetes, Type 2

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46OMIM
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Clinical features from OMIM:

125853

Clinical synopsis from OMIM:

125853

Drugs & Therapeutics for Diabetes, Type 2

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Genetic Tests for Diabetes, Type 2

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Anatomical Context for Diabetes, Type 2

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32MalaCards
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MalaCards organs/tissues related to Diabetes, Type 2:

32
Eye, Heart, Kidney, Testes

Animal Models for Diabetes, Type 2 or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Diabetes, Type 2:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053759.0GPD2, PPARG

Publications for Diabetes, Type 2

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Genetic Variations for Diabetes, Type 2

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62UniProtKB/Swiss-Prot
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Genetic disease variations for Diabetes, Type 2:

62 (show all 11)
id Symbol AA change Variation ID SNP ID
1AKT2p.Arg274HisVAR_067310
2HNF1Bp.Ser465ArgVAR_017665
3HNF4Ap.Val402IleVAR_004670rs137853337
4INSRp.Arg1191GlnVAR_004098
5INSRp.Thr858AlaVAR_015917rs182552223
6INSRp.Arg1158GlnVAR_015927
7IRS1p.Ser1043TyrVAR_005302
8IRS1p.Cys1095TyrVAR_005303
9MAPK8IP1p.Ser59AsnVAR_012243
10PPP1R3Ap.Ala931GluVAR_019699rs35449651
11SLC2A4p.Val383IleVAR_007170rs121434581

Expression for genes affiliated with Diabetes, Type 2

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Diabetes, Type 2

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Pathways for genes affiliated with Diabetes, Type 2

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Compounds for genes affiliated with Diabetes, Type 2

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44Novoseek, 24HMDB
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Compounds related to Diabetes, Type 2 according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1glycerol 3-phosphate44 2410.0GPD2, PPARG

GO Terms for genes affiliated with Diabetes, Type 2

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Products for genes affiliated with Diabetes, Type 2

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Diabetes, Type 2

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet