Aliases & Classifications for Diabetic Foot Ulcers

Aliases & Descriptions for Diabetic Foot Ulcers:

Name: Diabetic Foot Ulcers 38 52
Diabetic Foot Ulcer 69
Diabetic Foot 69

Summaries for Diabetic Foot Ulcers

MalaCards based summary : Diabetic Foot Ulcers, also known as diabetic foot ulcer, is related to peripheral vascular disease and upper respiratory tract disease, and has symptoms including angina pectoris, back pain and chest pain. An important gene associated with Diabetic Foot Ulcers is PDGFB (Platelet Derived Growth Factor Subunit B), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Zinc and Aspirin have been mentioned in the context of this disorder. Affiliated tissues include Bone, bone and skin, and related phenotypes are homeostasis/metabolism and cardiovascular system

Related Diseases for Diabetic Foot Ulcers

Diseases related to Diabetic Foot Ulcers via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 87)
id Related Disease Score Top Affiliating Genes
1 peripheral vascular disease 29.5 MMP1 PDGFB
2 upper respiratory tract disease 10.1 PDGFB TGFB1
3 natural killer cell leukemia 10.1 CRP MMP9
4 pituitary infarct 10.1 MMP9 TGFB1
5 lipodystrophy, familial partial, type 1 10.1 CRP TGFB1
6 central epithelioid sarcoma 10.1 CRP MMP9
7 osteomyelitis 10.1
8 subacute glomerulonephritis 10.1 CRP TGFB1
9 hyperlucent lung 10.1 CRP MMP9
10 brain ischemia 10.1 CRP TGFB1
11 henoch-schoenlein purpura 10.0 HIF1A TGFB1
12 ischemia 10.0
13 strawberry gallbladder 10.0 CRP TGFB1
14 kleptomania 10.0 MMP1 MMP9
15 adult-onset distal myopathy due to vcp mutation 10.0 MMP1 MMP9
16 chordoid meningioma 10.0 CRP MMP9
17 senile atrophy of choroid 10.0 MMP1 MMP9
18 ectropion 10.0 MMP1 MMP9
19 cystic lymphangioma 10.0 MMP1 MMP9
20 linear porokeratosis 10.0 MMP1 MMP9
21 urinary bladder posterior wall cancer 10.0 CRP HIF1A
22 myiasis 10.0 CRP TGFB1
23 adult neuronal ceroid lipofuscinosis 10.0 MMP1 MMP9
24 onychocytic matricoma 10.0 MMP1 MMP9
25 noonan syndrome 4 10.0 MMP1 TGFB1
26 burns 10.0 MMP9 PDGFB TGFB1
27 renal tubular acidosis 10.0 MMP9 PDGFB TGFB1
28 laryngostenosis 10.0 MMP1 MMP9
29 catecholaminergic polymorphic ventricular tachycardia 10.0 MMP1 TGFB1
30 leber congenital amaurosis 10.0 MMP1 TGFB1
31 hereditary night blindness 10.0 MMP1 TGFB1
32 nodular cutaneous amyloidosis 10.0 MMP1 MMP9
33 zika fever 10.0 MMP1 TGFB1
34 infancy electroclinical syndrome 10.0 CRP MMP9
35 cholera 10.0 MMP1 TGFB1
36 systolic heart failure 10.0 CRP TGFB1
37 limb ischemia 10.0
38 myelophthisic anemia 10.0 CRP MMP9 PDGFB
39 hypogonadotropic hypogonadism 20 with or without anosmia 9.9 HIF1A MMP9 TGFB1
40 breast abscess 9.9 MMP1 MMP9
41 intra-abdominal lymph node mast cell malignancy 9.9 CRP MMP9
42 xerophthalmia 9.9 CRP MMP1
43 renal oncocytoma 9.9 MMP1 MMP9
44 carotenemia 9.9 CRP MMP1
45 acute chest syndrome 9.9 CRP MMP9 TGFB1
46 unilateral hypoactive labyrinth 9.9 CRP MMP9
47 autoimmune-related retinopathy and optic neuropathy 9.9 CRP MMP9 TGFB1
48 critical limb ischemia 9.9
49 artery disease 9.9
50 peripheral artery disease 9.9

Graphical network of the top 20 diseases related to Diabetic Foot Ulcers:



Diseases related to Diabetic Foot Ulcers

Symptoms & Phenotypes for Diabetic Foot Ulcers

UMLS symptoms related to Diabetic Foot Ulcers:


angina pectoris, back pain, chest pain, edema, headache, muscle cramp, pain, sciatica, seizures, syncope, tremor, chronic pain, vertigo/dizziness, sleeplessness

MGI Mouse Phenotypes related to Diabetic Foot Ulcers:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.8 CRP HIF1A MMP1 MMP9 PDGFB TGFB1
2 cardiovascular system MP:0005385 9.77 CRP HIF1A MMP9 PDGFB TGFB1
3 immune system MP:0005387 9.73 CRP HIF1A MMP1 MMP9 PDGFB TGFB1
4 neoplasm MP:0002006 9.46 HIF1A MMP1 MMP9 TGFB1
5 renal/urinary system MP:0005367 9.26 HIF1A MMP9 PDGFB TGFB1
6 respiratory system MP:0005388 8.92 TGFB1 HIF1A MMP9 PDGFB

Drugs & Therapeutics for Diabetic Foot Ulcers

Drugs for Diabetic Foot Ulcers (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 370)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Zinc Approved Phase 4,Phase 3 7440-66-6 32051 23994
2
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
3
Ciprofloxacin Approved, Investigational Phase 4,Phase 2,Phase 1 85721-33-1 2764
4
Ofloxacin Approved Phase 4,Phase 3,Phase 2 82419-36-1 4583
5
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613 2171
6
Sulfamethoxazole Approved Phase 4,Phase 2 723-46-6 5329
7
Metronidazole Approved Phase 4,Phase 2 443-48-1 4173
8
Trimethoprim Approved, Vet_approved Phase 4,Phase 2 738-70-5 5578
9
Linezolid Approved, Investigational Phase 4,Phase 2 165800-03-3 441401
10
Clindamycin Approved, Vet_approved Phase 4,Phase 2 18323-44-9 29029
11
Menthol Approved Phase 4,Phase 1,Phase 2 2216-51-5 16666
12
Tazobactam Approved Phase 4,Phase 3,Phase 2 89786-04-9 123630
13
Piperacillin Approved Phase 4,Phase 3,Phase 2 66258-76-2 43672
14
Aztreonam Approved Phase 4,Phase 2 78110-38-0 5362041 5742832
15
Daptomycin Approved, Investigational Phase 4,Phase 3,Phase 2 103060-53-3 16129629
16
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2 100986-85-4 149096
17
Nitroprusside Approved Phase 4 15078-28-1 11963622
18
Coal tar Approved Phase 4 8007-45-2
19
Rifampin Approved Phase 4 13292-46-1 5458213 5381226
20
Nitroglycerin Approved, Investigational Phase 4,Phase 2 55-63-0 4510
21
Acetylcholine Approved Phase 4 51-84-3 187
22
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
23
Vancomycin Approved Phase 4,Phase 3,Phase 2 1404-90-6 441141 14969
24
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 564-25-0 54671203
25
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
26
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
27
Cefotaxime Approved Phase 4 63527-52-6 456256 5742673
28
Fusidic Acid Approved Phase 4 6990-06-3 3000226
29
Sulbactam Approved Phase 4 68373-14-8
30
Cefoxitin Approved Phase 4 35607-66-0 441199
31
Cefepime Approved Phase 4,Phase 2 88040-23-7 5479537
32
Ertapenem Approved, Investigational Phase 4,Phase 3 153832-46-3 150610
33
Linagliptin Approved Phase 4 668270-12-0 10096344
34
Petrolatum Approved Phase 4 8009-03-8
35
Saxagliptin Approved Phase 4 361442-04-8 11243969
36
Insulin Aspart Approved Phase 4 116094-23-6 16132418
37
Dimenhydrinate Approved Phase 4 523-87-5 441281
38
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 439542 10909430
39
leucovorin Approved, Nutraceutical Phase 4,Phase 2 58-05-9 54575, 6560146 143
40
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-30-3 6037
41
Riboflavin Approved, Nutraceutical, Vet_approved Phase 4 83-88-5 493570
42
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
43 insulin Phase 4,Phase 3
44 Clavulanic Acid Phase 4,Phase 3,Phase 2
45
protease inhibitors Phase 4,Phase 3,Early Phase 1
46 Mitogens Phase 4,Phase 3,Phase 2,Phase 1
47 Folic Acid Antagonists Phase 4,Phase 2
48 Clindamycin palmitate Phase 4,Phase 2
49 Clindamycin phosphate Phase 4,Phase 2
50 Gentamicins Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 608)
id Name Status NCT ID Phase
1 Efficacy and Safety of Garamycin® Sponge (Gentamicin-Collagen Sponge) in Diabetic Patients With a Moderate or Severe Foot Ulcer Infection Unknown status NCT01951768 Phase 4
2 Outcomes of Non-infected Diabetic Foot Ulcers With/Without Antibiotics Unknown status NCT01418456 Phase 4
3 Clinical Evaluation of the SNaP Wound Care System Unknown status NCT01113658 Phase 4
4 Bi-Axial Rotating Magnetic Field Therapy in Refractory Neuropathic Foot Pain Secondary to Diabetic Peripheral Neuropathy Unknown status NCT00123136 Phase 4
5 Optimized Strategy for Diabetic Patients With Critical Limb Ischemia(Part II) (DCLI-II) Unknown status NCT01173094 Phase 4
6 Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers Completed NCT02209051 Phase 4
7 Using Santyl on Diabetic Foot Ulcers Completed NCT01408277 Phase 4
8 Santyl Applications to Diabetic Foot Ulcers Completed NCT02111291 Phase 4
9 Diabetic Foot Ulcer Study on Topical Interventions Completed NCT02577900 Phase 4
10 GrafixCORE®: Open-Label Study to Evaluate the Safety and Efficacy of GrafixCORE® for Complex Diabetic Foot Wounds Completed NCT02260609 Phase 4
11 Randomized, Controlled Multicenter Trial of Vacuum Assisted Closure Therapy™ in Diabetic Foot Ulcers Completed NCT00432965 Phase 4
12 Grafix® DFU: Open-Label Extension Option to Evaluate Safety & Efficacy of Grafix® for Chronic Diabetic Foot Ulcers Completed NCT01596920 Phase 4
13 LeucoPatch™ Study A Multicenter Study on the Effect of LeucoPatch™ in Diabetic Foot Ulcers Completed NCT01454401 Phase 4
14 Trial of Vacuum Assisted Closure® Therapy in Amputation Wounds of the Diabetic Foot Completed NCT00224796 Phase 4
15 Use of Santyl in Diabetic Foot Ulcers Completed NCT02581488 Phase 4
16 Study of Oasis Ultra in Diabetic Foot Ulcers Completed NCT01835379 Phase 4
17 Evaluation of the Effect of Vivostat Platelet Rich Fibrin(PRF) in the Treatment of Diabetic Foot Ulcers Completed NCT00770939 Phase 4
18 Antibiotic Treatment Duration for Non-Surgically-Treated Diabetic Foot Osteomyelitis Completed NCT02123628 Phase 4
19 A Study to Look at the Effects of Four Weeks of Treatment on the Healing of Diabetic Foot Ulcers Completed NCT01143714 Phase 4
20 Santyl vs. Sharp Debridement of Diabetic Foot Wounds Completed NCT01056198 Phase 4
21 TITLE: An Open, Non-comparative, Multi-centre Post Marketing Clinical Follow-up (PMCF) Investigation to Evaluate Performance and Safety on Diabetic Foot Ulcer, DFU, When Using Mepilex Transfer Ag as Intended Completed NCT01964521 Phase 4
22 Enzymatic Versus (vs) Autolytic Debridement of Diabetic Foot Ulcers Completed NCT01143727 Phase 4
23 DermACELL in Subjects With Chronic Wounds of the Lower Extremities Completed NCT01970163 Phase 4
24 Diabetic Foot Ulcer. Effectiveness of Chlorhexidine Gluconate 0.125 % Compared With Sterile Deionized Water Completed NCT02097615 Phase 4
25 Evaluation of the Clinical Effectiveness of a Collagen-ORC Antimicrobial Matrix in Full-Thickness, Neuropathic Diabetic Foot Ulcers Completed NCT00235196 Phase 4
26 Study Evaluating the Safety and Efficacy of Piperacillin/Tazobactam and Ampicillin/Sulbactam in Patients With Diabetic Foot Infections Completed NCT00044746 Phase 4
27 Wound Edge Changes Following Treatment With Santyl Completed NCT01197898 Phase 4
28 OASIS Wound Matrix (Oasis) Mechanism of Action Completed NCT00570141 Phase 4
29 Polydeoxyribonucleotide -Placentex Mastelli(Pdrn) for the Treatment of Diabetic Ulcers Completed NCT00638872 Phase 4
30 Hyperbaric Oxygen Therapy as Adjunctive Treatment of Chronic Diabetic Foot Ulcers Completed NCT00953186 Phase 4
31 Study Comparing VERSAJET With Conventional Surgical Procedures in the Removal of Unhealthy Tissue From Lower Limb Ulcers Completed NCT00521027 Phase 4
32 Target Site Pharmacokinetics of Ertapenem After Multiple Doses in Diabetes Patients With Soft Tissue Infection Completed NCT00658866 Phase 4
33 Skin Ulcers Treatment With an Handicraft Topical Device Completed NCT02512159 Phase 4
34 A Complicated Skin and Soft-tissue Infection Patient Registry Completed NCT00737269 Phase 4
35 Hyperbaric Oxygen Therapy (HBOT) for Chronic Diabetic Lower Limb Ulcers Completed NCT00621608 Phase 4
36 Effect of Pulsing Electrical Fields on Lower Extremity Diabetic Neuropathy: A Pilot, Open-Label Study Completed NCT00614341 Phase 4
37 Lovaza® and Microvascular Function in Type 2 Diabetes Completed NCT00931879 Phase 4
38 The Effect of Linagliptin on Mitochondrial and Endothelial Function Completed NCT01969084 Phase 4
39 Evaluation of Woulgan in Diabetic Foot Ulcer Recruiting NCT02631512 Phase 4
40 A Comparative Efficacy Study of DermaPure™ to Treat Diabetic Foot Ulcers Recruiting NCT02081352 Phase 4
41 LeucoPatch in the Management of Hard-to-heal Diabetic Foot Ulcers Recruiting NCT02224742 Phase 4
42 A Feasibility Study of the ReGenerCell™ Autologous Cell Harvesting Device for Diabetic Foot Ulcers Recruiting NCT02799121 Phase 4
43 Effectiveness of Aurix Therapy in Diabetic Foot Ulcers Recruiting NCT02352480 Phase 4
44 Maggot Debridement Therapy Versus Conventional Dressing Therapy to Treat Diabetic Foot Ulcers Recruiting NCT02816749 Phase 4
45 GrafixPRIME® for the Treatment of Chronic Diabetic Foot Ulcers Recruiting NCT02675855 Phase 4
46 Dipeptidyl Peptidase 4 Inhibition Facilitate Healing of Diabetic Ulcers Recruiting NCT02742233 Phase 4
47 Single-Use Negative Pressure Wound Therapy System vs. Traditional Negative Pressure Wound Therapy System (tNPWT) Recruiting NCT02470806 Phase 4
48 A Comparison of TCC-EZ Using Human Amnion Allograft vs TCC-EZ and Standard Wound Care in Treating Diabetic Foot Ulcers. Active, not recruiting NCT02344329 Phase 4
49 Insulin Infusion Diabetes Ulcer Enrolling by invitation NCT00700154 Phase 4
50 Evaluation Of An Advanced Borderless Dressing Not yet recruiting NCT03146845 Phase 4

Search NIH Clinical Center for Diabetic Foot Ulcers

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Diabetic Foot Ulcers cell therapies at LifeMap Discovery.

Genetic Tests for Diabetic Foot Ulcers

Anatomical Context for Diabetic Foot Ulcers

MalaCards organs/tissues related to Diabetic Foot Ulcers:

39
Bone, Skin, Bone Marrow, Colon, Testes, Endothelial, Kidney
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Diabetic Foot Ulcers:
id Tissue Anatomical CompartmentCell Relevance
1 Bone Bone Marrow Bone Marrow Stromal Cells Potential therapeutic candidate

Publications for Diabetic Foot Ulcers

Articles related to Diabetic Foot Ulcers:

(show top 50) (show all 632)
id Title Authors Year
1
Vitamin D receptor gene FokI variant in diabetic foot ulcer and its relation with oxidative stress. ( 27836663 )
2017
2
Effect of limb preservation status and body mass index on the survival of patients with limb-threatening diabetic foot ulcers. ( 27751708 )
2017
3
Association of Sociodemographic Factors with Spirituality and Hope in Patients with Diabetic Foot Ulcers. ( 27984272 )
2017
4
Effects of insulin on the skin: possible healing benefits for diabetic foot ulcers. ( 27655635 )
2016
5
Open, non-comparative, multi-centre post clinical study of the performance and safety of a gelling fibre wound dressing on diabetic foot ulcers. ( 27169344 )
2016
6
Effect of total contact cast in non-healing diabetic foot ulcers in Lebanese patients. ( 27611341 )
2016
7
Dressing and Diabetic Foot Ulcers: A Current Review of the Evidence. ( 27556756 )
2016
8
A prospective, randomised, controlled, multicentre clinical trial examining healing rates, safety and cost to closure of an acellular reticular allogenic human dermis versus standard of care in the treatment of chronic diabetic foot ulcers. ( 27073000 )
2016
9
Comparison of five systems of classification of diabetic foot ulcers and predictive factors for amputation. ( 27723246 )
2016
10
Localization of human adipose-derived stem cells and their effect in repair of diabetic foot ulcers in rats. ( 27770835 )
2016
11
Plantar pressures are higher in cases with diabetic foot ulcers compared to controls despite a longer stance phase duration. ( 27629263 )
2016
12
An integrated wound-care pathway, supported by telemedicine, and competent wound management-Essential in follow-up care of adults with diabetic foot ulcers. ( 27573312 )
2016
13
Virulence determinants in clinical Staphylococcus aureus from monomicrobial and polymicrobial infections of diabetic foot ulcers. ( 27902390 )
2016
14
Implementation of foot thermometry plus mHealth to prevent diabetic foot ulcers: study protocol for a randomized controlled trial. ( 27094007 )
2016
15
Expression of TGF-I^1 and miRNA-145 in patients with diabetic foot ulcers. ( 27168843 )
2016
16
Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers. ( 27896528 )
2016
17
Study of risk factors and outcome of patients with diabetic foot ulcers. ( 27728118 )
2016
18
Comparing the efficacies of alginate, foam, hydrocolloid, hydrofiber, and hydrogel dressings in the management of diabetic foot ulcers and venous leg ulcers: a systematic review and meta-analysis examining how to dress for success. ( 27617934 )
2016
19
Influence of beliefs about health and illness on self-care and care-seeking in foreign-born people with diabetic foot ulcers: dissimilarities related to origin. ( 27827276 )
2016
20
Cardiovascular Autonomic Dysfunction Predicts Diabetic Foot Ulcers in Patients With Type 2 Diabetes Without Diabetic Polyneuropathy. ( 27015188 )
2016
21
Preliminary Evaluation of a Cycling Cleat Designed for Diabetic Foot Ulcers. ( 27824259 )
2016
22
Incident diabetic foot ulcers and mortality in hemodialysis patients. ( 27624300 )
2016
23
Composite Skin Grafting with Human Acellular Dermal Matrix Scaffold for Treatment of Diabetic Foot Ulcers: A Randomized Controlled Trial. ( 27068845 )
2016
24
Extracorporeal shockwave therapy in the treatment of chronic diabetic foot ulcers: a prospective randomised trial. ( 27827284 )
2016
25
Risk of contrast induced nephropathy in diabetic patients affected by critical limb ischemia and diabetic foot ulcers treated by percutaneous transluminal angioplasty of lower limbs. ( 27786404 )
2016
26
A Retrospective Case Series of a Dehydrated Amniotic Membrane Allograft for Treatment of Unresolved Diabetic Foot Ulcers. ( 27439322 )
2016
27
Guar gum as a new antimicrobial peptide delivery system against diabetic foot ulcers Staphylococcus aureus isolates. ( 27498987 )
2016
28
Platelet-Rich Plasma for the Treatment of Clean Diabetic Foot Ulcers. ( 27522981 )
2016
29
The Incidence of Confounding Factors in Patients With Diabetes Mellitus Hospitalized for Diabetic Foot Ulcers. ( 27560472 )
2016
30
An Alteration of Lymphocytes Subpopulations and Immunoglobulins Levels in Patients with Diabetic Foot Ulcers Infected Particularly by Resistant Pathogens. ( 28050566 )
2016
31
The Use of Micronized Dehydrated Human Amnion/Chorion Membrane Allograft for the Treatment of Diabetic Foot Ulcers: A Case Series. ( 27191173 )
2016
32
Physiological and Psychological Challenges of Increasing Physical Activity and Exercise in Patients at Risk of Diabetic Foot Ulcers: A Critical Review. ( 27155091 )
2016
33
The Most Prevalent Organism in Diabetic Foot Ulcers and Its Drug Sensitivity and Resistance to Different Standard Antibiotics. ( 27097700 )
2016
34
Raised serum 25-hydroxyvitamin D levels in patients with active diabetic foot ulcers. ( 27153203 )
2016
35
Epidemiology of Diabetic Foot Ulcers and Amputations in Romania: Results of a Cross-Sectional Quality of Life Questionnaire Based Survey. ( 27019852 )
2016
36
Integrative Analysis of miRNA and mRNA Paired Expression Profiling of Primary Fibroblast Derived from Diabetic Foot Ulcers Reveals Multiple Impaired Cellular Functions. ( 27607190 )
2016
37
Tinea pedis and onychomycosis frequency in diabetes mellitus patients and diabetic foot ulcers. A cross sectional - observational study. ( 27648034 )
2016
38
Systematic review and meta-analysis of skin substitutes in the treatment of diabetic foot ulcers: Highlights of a Cochrane Systematic review. ( 27062201 )
2016
39
Increasing the miR-126 expression in the peripheral blood of patients with diabetic foot ulcers treated with maggot debridement therapy. ( 27623390 )
2016
40
Clinical effectiveness of hemoglobin spray (Granulox(Ar)) as adjunctive therapy in the treatment of chronic diabetic foot ulcers. ( 27829487 )
2016
41
Topical oxygen therapy results in complete wound healing in diabetic foot ulcers. ( 27733020 )
2016
42
Primary wound closure of diabetic foot ulcers by debridement and stitching. ( 27827282 )
2016
43
The accuracy and cost-effectiveness of strategies used to identify peripheral artery disease among patients with diabetic foot ulcers. ( 27575813 )
2016
44
Prevalence and prognostic value of depression and anxiety in patients with diabetic foot ulcers and possibilities of their treatment. ( 27211285 )
2016
45
Measuring Weight-Bearing Activities in Patients With Previous Diabetic Foot Ulcers. ( 27556347 )
2016
46
Effectiveness of offloading methods in preventing primary diabetic foot ulcers in adults with diabetes: a systematic review. ( 27532798 )
2016
47
Safety and effectiveness of therapeutic magnetic resonance in diabetic foot ulcers: a prospective randomised controlled trial. ( 27974006 )
2016
48
Management of diabetic foot ulcers: evaluation of case studies. ( 27523769 )
2016
49
Poorly designed research does not help clarify the role of hyperbaric oxygen in the treatment of chronic diabetic foot ulcers. ( 27723012 )
2016
50
Descriptive, Longitudinal Study Results Applied to Statistical Models to Assess the Impact of Early Microbiological Cultures on the Economic Burden of Treatment for Infected Diabetic Foot Ulcers at a Mexican Public Health Facility. ( 28054923 )
2016

Variations for Diabetic Foot Ulcers

Expression for Diabetic Foot Ulcers

Search GEO for disease gene expression data for Diabetic Foot Ulcers.

Pathways for Diabetic Foot Ulcers

Pathways related to Diabetic Foot Ulcers according to GeneCards Suite gene sharing:

(show all 23)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.58 CRP HIF1A MMP1 MMP9 PDGFB TGFB1
2
Show member pathways
12.97 HIF1A MMP1 MMP9 PDGFB TGFB1
3
Show member pathways
12.39 MMP1 MMP9 PDGFB TGFB1
4 11.98 HIF1A MMP9 TGFB1
5 11.95 HIF1A MMP1 MMP9 PDGFB TGFB1
6 11.87 MMP1 MMP9 TGFB1
7 11.52 HIF1A MMP9 TGFB1
8 11.51 HIF1A MMP1 MMP9 TGFB1
9 11.47 MMP1 MMP9
10
Show member pathways
11.43 PDGFB TGFB1
11 11.42 HIF1A MMP9
12 11.4 MMP9 TGFB1
13
Show member pathways
11.38 MMP1 MMP9
14 11.36 MMP1 MMP9
15 11.34 MMP9 PDGFB TGFB1
16 11.3 HIF1A PDGFB
17 11.24 PDGFB TGFB1
18 11.21 HIF1A MMP1 TGFB1
19 11.14 MMP1 MMP9
20 11.07 MMP1 MMP9
21
Show member pathways
11 CRP HIF1A
22 10.81 HIF1A MMP9 PDGFB
23 10.03 MMP1 MMP9 TGFB1

GO Terms for Diabetic Foot Ulcers

Cellular components related to Diabetic Foot Ulcers according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 CRP MMP1 MMP9 PDGFB TGFB1
2 proteinaceous extracellular matrix GO:0005578 9.33 MMP1 MMP9 TGFB1
3 platelet alpha granule lumen GO:0031093 9.26 PDGFB TGFB1
4 extracellular matrix GO:0031012 8.92 MMP1 MMP9 PDGFB TGFB1

Biological processes related to Diabetic Foot Ulcers according to GeneCards Suite gene sharing:

(show all 22)
id Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.67 MMP1 MMP9 TGFB1
2 extracellular matrix disassembly GO:0022617 9.61 MMP1 MMP9
3 response to wounding GO:0009611 9.6 PDGFB TGFB1
4 positive regulation of endothelial cell proliferation GO:0001938 9.59 HIF1A PDGFB
5 collagen catabolic process GO:0030574 9.58 MMP1 MMP9
6 positive regulation of MAP kinase activity GO:0043406 9.58 PDGFB TGFB1
7 positive regulation of cell migration GO:0030335 9.58 MMP9 PDGFB TGFB1
8 cellular response to growth factor stimulus GO:0071363 9.57 PDGFB TGFB1
9 positive regulation of fibroblast proliferation GO:0048146 9.56 PDGFB TGFB1
10 positive regulation of cell division GO:0051781 9.55 PDGFB TGFB1
11 epithelial to mesenchymal transition GO:0001837 9.54 HIF1A TGFB1
12 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 9.52 PDGFB TGFB1
13 positive regulation of vascular endothelial growth factor production GO:0010575 9.51 HIF1A TGFB1
14 positive regulation of blood vessel endothelial cell migration GO:0043536 9.48 PDGFB TGFB1
15 embryonic placenta development GO:0001892 9.46 HIF1A PDGFB
16 positive regulation of gene expression GO:0010628 9.46 CRP HIF1A PDGFB TGFB1
17 negative regulation of ossification GO:0030279 9.43 HIF1A TGFB1
18 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.37 MMP9 PDGFB
19 positive regulation of chemotaxis GO:0050921 9.32 PDGFB TGFB1
20 positive regulation of superoxide anion generation GO:0032930 9.26 CRP TGFB1
21 connective tissue replacement involved in inflammatory response wound healing GO:0002248 8.96 HIF1A TGFB1
22 positive regulation of pri-miRNA transcription from RNA polymerase II promoter GO:1902895 8.8 HIF1A PDGFB TGFB1

Molecular functions related to Diabetic Foot Ulcers according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 collagen binding GO:0005518 8.62 MMP9 PDGFB

Sources for Diabetic Foot Ulcers

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....