MCID: DBT006
MIFTS: 54

Diabetic Macular Edema malady

Eye diseases category
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Summaries for Diabetic Macular Edema

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Wikipedia:65 Diabetic retinopathy, ([?r?tn??p??i]) is retinopathy (damage to the retina) caused by complications of... more...

MalaCards based summary: Diabetic Macular Edema is related to retinal vein occlusion and retinal detachment. An important gene associated with Diabetic Macular Edema is SERPINF1 (serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1), and among its related pathways are Immune response Oncostatin M signaling via JAK Stat in human cells and LDL Oxidation in Atherogenesis. The compounds olmesartan and perindopril have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and endothelial, and related mouse phenotypes are tumorigenesis and endocrine/exocrine gland.

Aliases & Classifications for Diabetic Macular Edema

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Diabetic Macular Edema, Aliases & Descriptions:

Name: Diabetic Macular Edema 8 10 44 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


External Ids:

Disease Ontology8 DOID:9191
SNOMED-CT57 312912001
ICD9CM27 362.07

Related Diseases for Diabetic Macular Edema

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Diseases related to Diabetic Macular Edema via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 136)
idRelated DiseaseScoreTop Affiliating Genes
1retinal vein occlusion31.5VEGFA
2retinal detachment31.3VEGFA, SERPINF1
3blindness30.4INS, VEGFA, SERPINF1, PRKCB, AKR1B1
4proliferative diabetic retinopathy30.4SERPINF1, VEGFA, ICAM1, SST, CCL2, FGF2
5neuropathy30.3SOD2, AKR1B1, INS
6type 1 diabetes mellitus30.2PRKCB, SST, AKR1B1, INS
7ischemia30.0VEGFA, ICAM1, FGF2, NOS3, SOD2, AKR1B1
8diabetic retinopathy29.9SERPINF1, SOD2, PRKCB, AKR1B1, ICAM1, DYT10
9diabetes mellitus28.4NOS3, DYT10, IL6, CCL2, SST, ICAM1
10retinitis11.1
11endotheliitis10.8
12cataract10.7
13age related macular degeneration10.6
14central retinal vein occlusion10.6VEGFA
15vitreous detachment10.6
16dengue shock syndrome10.6THBD
17diabetic autonomic neuropathy10.6AKR1B1
18hypoaldosteronism10.6REN
19gitelman syndrome10.6REN
20low renin hypertension10.6REN
21retinopathy of prematurity10.5VEGFA
22malaria10.5ICAM1
23diabetic cataract10.5AKR1B1
24angiodysplasia10.5SST
25dumping syndrome10.5SST
26leukostasis10.5ICAM1
27rheumatoid vasculitis10.5ICAM1
28zollinger-ellison syndrome10.4SST
29meningioma10.4SST
30macular retinal edema10.4VEGFA, SERPINF1, PRKCB
31ovarian hyperstimulation syndrome10.4REN, VEGFA
32sleep disorder10.3
33poems syndrome10.3IL6, VEGFA
34allergic contact dermatitis10.3ICAM1, DYT10
35vascular cancer10.3VEGFA, FGF2
36pure autonomic failure10.3EPO, REN
37hypoglycemic coma10.3INS
38retinal vascular disease10.3DYT10, SERPINF1, VEGFA, AKR1B1
39corneal neovascularization10.3VEGFA, FGF2, SERPINF1
40hemangioblastoma10.3EPO, VEGFA
41peripheral vascular disease10.3INS
42glomerulosclerosis10.2CCL2, REN, AKR1B1
43retinal degeneration10.2FGF2, AKR1B1, SERPINF1
44lung adenocarcinoma10.2THBD, VEGFA, SOD2, DYT10
45myelofibrosis10.2EPO, FGF2
46factor vii deficiency10.2VEGFA, SST, FGF2
47impotence10.2DYT10, NOS3
48uveitis10.2SERPINF1, CCL2, ICAM1
49acute erythroid leukemia10.2PRKCB, DYT10, EPO
50burns10.2

Graphical network of the top 20 diseases related to Diabetic Macular Edema:



Diseases related to diabetic macular edema

Symptoms for Diabetic Macular Edema

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Drugs & Therapeutics for Diabetic Macular Edema

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Drug clinical trials:

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Search NIH Clinical Center for Diabetic Macular Edema

Genetic Tests for Diabetic Macular Edema

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Anatomical Context for Diabetic Macular Edema

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MalaCards organs/tissues related to Diabetic Macular Edema:

32
Eye, Retina, Endothelial, Testes

Animal Models for Diabetic Macular Edema or affiliated genes

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MGI Mouse Phenotypes related to Diabetic Macular Edema:

36 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.2VEGFA, SOD2, ICAM1, CCL2, IL6, FGF2
2MP:00053798.1NOS3, IL6, ICAM1, SERPINF1, VEGFA, INS
3MP:00053757.9INS, SOD2, CCL2, IL6, NOS3
4MP:00053677.9THBD, INS, VEGFA, SOD2, AKR1B1, REN
5MP:00028737.8THBD, INS, VEGFA, EPO, REN, SST
6MP:00053707.7THBD, INS, VEGFA, SOD2, EPO, CCL2
7MP:00053897.7THBD, INS, VEGFA, SERPINF1, SOD2, REN
8MP:00107717.7THBD, INS, VEGFA, SOD2, EPO, ICAM1
9MP:00053907.5INS, VEGFA, AKR1B1, CCL2, IL6, NOS3
10MP:00053817.5THBD, INS, VEGFA, SERPINF1, ICAM1, SST
11MP:00053697.3INS, VEGFA, SOD2, REN, ICAM1, CCL2
12MP:00053917.1INS, VEGFA, SERPINF1, SOD2, AKR1B1, ICAM1
13MP:00053876.9THBD, INS, VEGFA, SOD2, PRKCB, REN
14MP:00053846.8THBD, INS, VEGFA, SOD2, EPO, ICAM1
15MP:00053786.8THBD, INS, VEGFA, SOD2, AKR1B1, REN
16MP:00053976.5EPO, SOD2, VEGFA, INS, THBD, PRKCB
17MP:00107686.4EPO, SOD2, VEGFA, INS, THBD, AKR1B1
18MP:00053866.3AKR1B1, PRKCB, SOD2, VEGFA, INS, REN
19MP:00036316.3THBD, INS, VEGFA, SERPINF1, SOD2, PRKCB
20MP:00053856.3FGF2, THBD, INS, VEGFA, SERPINF1, SOD2
21MP:00053766.0PRKCB, EPO, SOD2, VEGFA, INS, THBD

Publications for Diabetic Macular Edema

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Articles related to Diabetic Macular Edema:

(show top 50)    (show all 536)
idTitleAuthorsYear
1
Intraretinal fibrosis in exudative diabetic macular edema after ranibizumab treatments. (25372542)
2014
2
Single injection of triamcinolone versus three repeated injections of bevacizumab for treatment of diabetic macular edema. (23334618)
2013
3
Enzymatic vitrectomy for diabetic retinopathy and diabetic macular edema. (24379923)
2013
4
Factors affecting visual outcomes in patients with diabetic macular edema treated with ranibizumab. (24263379)
2013
5
Development of a Semi-Automatic Segmentation Method for Retinal OCT Images Tested in Patients with Diabetic Macular Edema. (24386127)
2013
6
NAVILAS Laser System Focal Laser Treatment for Diabetic Macular Edema - One Year Results of a Case Series. (24082979)
2013
7
Risk factors associated with diabetic macular edema. (23380134)
2013
8
Psychometric validation of the Visual Function Questionnaire-25 in patients with diabetic macular edema. (23347793)
2013
9
Paired responses to intravitreal bevacizumab in diabetic macular edema: predictors of response in the fellow eye. (23873254)
2013
10
Vascular endothelial growth factor gene polymorphism prevalence in patients with diabetic macular edema and its correlation with anti-VEGF treatment outcomes. (23927080)
2013
11
Diabetic macular edema: Current management 2013. (24379911)
2013
12
Subtenon injection of natural leukocyte interferon I+-2a in diabetic macular edema: a case report. (24165224)
2013
13
Lipoxins, resolvins, and protectins in the prevention and treatment of diabetic macular edema and retinopathy. (22677359)
2013
14
Diabetic macular edema: New promising therapies. (24379924)
2013
15
Ranibizumab injection for diabetic macular edema: meta-analysis of systemic safety and systematic review. (23931473)
2013
16
Classification of diabetic retinopathy and diabetic macular edema. (24379919)
2013
17
Intravitreal bevacizumab may increase diabetic macular edema in eyes with attached posterior vitreous. (23467022)
2013
18
Structural changes in individual retinal layers in diabetic macular edema. (24073417)
2013
19
Vitrectomy combined with intravitreal triamcinolone acetonide injection and macular laser photocoagulation for nontractional diabetic macular edema. (23730111)
2013
20
Optical coherence tomography in diabetic macular edema: patterns and related risk factors. (24172553)
2013
21
Two-year results of a randomized trial of intravitreal bevacizumab alone or combined with triamcinolone versus laser in diabetic macular edema. (22234244)
2012
22
Sustained delivery fluocinolone acetonide vitreous inserts provide benefit for at least 3 years in patients with diabetic macular edema. (22727177)
2012
23
Oral minocycline for the treatment of diabetic macular edema (DME): results of a phase I/II clinical study. (22589436)
2012
24
Dose-ranging evaluation of intravitreal siRNA PF-04523655 for diabetic macular edema (the DEGAS study). (23074206)
2012
25
Evaluation of a Novel, Non Contact, Automated Focal Laser with Integrated (NAVILAS) Fluorescein Angiography for Diabetic Macular Edema. (22346133)
2012
26
Factors associated with changes in visual acuity and central subfield thickness at 1 year after treatment for diabetic macular edema with ranibizumab. (22965591)
2012
27
Intravitreal injection of commercially available ketorolac tromethamine in eyes with diabetic macular edema refractory to laser photocoagulation. (21780926)
2011
28
Visual outcome after intravitreal triamcinolone acetonide depends on optical coherence tomographic patterns in patients with diffuse diabetic macular edema. (21836404)
2011
29
Comparison of intravitreal bevacizumab and ranibizumab treatment for diabetic macular edema. (21631366)
2011
30
Imaging of diabetic retinopathy and diabetic macular edema. (21607565)
2011
31
Correlation of macular thickness and posterior hyaloid change following bevacizumab and triamcinolone in diffuse diabetic macular edema in middle-aged patients. (21979875)
2011
32
Targeting the pathophysiology of diabetic macular edema. (20980428)
2010
33
Effect of retinal photocoagulation on intraretinal lipid exudates in diabetic macular edema documented by optical coherence tomography. (20079541)
2010
34
Pattern electroretinogram changes after intravitreal bevacizumab injection for diabetic macular edema. (20140695)
2010
35
Correlation between visual acuity and foveal microstructural changes in diabetic macular edema. (19996821)
2010
36
Polyunsaturated Fatty Acid Composition of Surgically Removed Hard Exudates in Diabetic Macular Edema. (20337342)
2010
37
Randomized controlled trial of an intravitreous dexamethasone drug delivery system in patients with diabetic macular edema. (20212197)
2010
38
Dose dependent effects of intravitreal triamcinolone acetonide on diffuse diabetic macular edema. (19568355)
2009
39
Diabetic macular edema. (23960851)
2009
40
Update on laser treatment of diabetic macular edema. (19349789)
2009
41
Intravitreal combination of triamcinolone acetonide and bevacizumab (Kenacort-Avastin) in diffuse diabetic macular edema. (19954371)
2009
42
Effect of vitrectomy on macular microcirculation in patients with diffuse diabetic macular edema. (19294405)
2009
43
Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema. (18708615)
2009
44
Diabetic macular edema. (19729104)
2009
45
The article by Kook et al 1 on the 1-year effect of bevacizumab in patients with chronic diffuse diabetic macular edema (DME). (19430285)
2009
46
Prevention of vision loss after cataract surgery in diabetic macular edema with intravitreal bevacizumab: a pilot study. (19357559)
2009
47
Surgical and anatomical outcomes of pars plana vitrectomy for diffuse nontractional diabetic macular edema. (18327133)
2008
48
Comparative therapy evaluation of intravitreal bevacizumab and triamcinolone acetonide on persistent diffuse diabetic macular edema. (19027427)
2008
49
Vitreous surgery for diabetic macular edema--its prognosis and correlation between preoperative systemic and ocular conditions and visual outcome. (18025629)
2007
50
Vitreous levels of interleukin-6 and vascular endothelial growth factor are related to diabetic macular edema. (13129863)
2003

Variations for Diabetic Macular Edema

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Expression for genes affiliated with Diabetic Macular Edema

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Expression patterns in normal tissues for genes affiliated with Diabetic Macular Edema

Search GEO for disease gene expression data for Diabetic Macular Edema.

Pathways for genes affiliated with Diabetic Macular Edema

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Pathways related to Diabetic Macular Edema according to GeneCards/GeneDecks:

(show all 30)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9CCL2, VEGFA
29.8CCL2, ICAM1
3
Show member pathways
Angiogenesis37
9.4FGF2, NOS3, VEGFA
49.3VEGFA, SST, IL6
59.3REN, NOS3, FGF2
6
Show member pathways
9.3NOS3, PRKCB, VEGFA, THBD
79.3IL6, ICAM1, PRKCB
89.3NOS3, PRKCB, INS
9
Show member pathways
9.2FGF2, NOS3, PRKCB, VEGFA
109.1ICAM1, CCL2, IL6
119.1IL6, CCL2, ICAM1
129.1IL6, CCL2, ICAM1
13
Show member pathways
Signaling Pathways in Glioblastoma37
9.1INS, VEGFA, PRKCB, FGF2
14
Show member pathways
9.1INS, VEGFA, PRKCB, FGF2
15
Show member pathways
IL-9 Signaling Pathway37
Development Thrombopoietin regulated cell processes60
IL-7 Signaling Pathway37
Immune response IL 9 signaling pathway60
9.1IL6, PRKCB, INS
169.1THBD, INS, IL6
17
Show member pathways
PLK2 and PLK4 events37
Polo-like kinase signaling events in the cell cycle37
9.0INS, SOD2, IL6
18
Show member pathways
9.0VEGFA, SOD2, EPO, IL6
199.0FGF2, IL6, PRKCB, VEGFA
208.9VEGFA, ICAM1, CCL2, IL6
21
Show member pathways
8.9IL6, CCL2, ICAM1, PRKCB
22
Show member pathways
Development VEGF signaling via VEGFR2 generic cascades60
8.9VEGFA, PRKCB, ICAM1, CCL2, NOS3
238.8NOS3, IL6, CCL2, THBD
24
Show member pathways
IL23-mediated signaling events37
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling37
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
8.6CCL2, IL6, NOS3, FGF2
25
Show member pathways
thioredoxin pathway37
8.3INS, SOD2, ICAM1, CCL2, IL6
26
Show member pathways
8.3INS, REN, CCL2, IL6, FGF2
27
Show member pathways
8.2FGF2, IL6, CCL2, EPO, INS
288.1NOS3, IL6, PRKCB, EPO, VEGFA, INS
297.9INS, VEGFA, EPO, IL6, NOS3, FGF2
30
Show member pathways
7.5INS, VEGFA, SERPINF1, SOD2, EPO, CCL2

Compounds for genes affiliated with Diabetic Macular Edema

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Compounds related to Diabetic Macular Edema according to GeneCards/GeneDecks:

(show top 50)    (show all 224)
idCompoundScoreTop Affiliating Genes
1olmesartan44 28 1111.5INS, CCL2, REN, SERPINF1
2perindopril44 50 1111.5NOS3, REN, VEGFA, THBD
3aminoguanidine44 28 1111.4AKR1B1, SOD2, NOS3, EPO
4streptozotocin449.1INS, SERPINF1, SST, NOS3, AKR1B1
5gm-csf44 2810.0EPO, ICAM1, CCL2, IL6, VEGFA
6cyclophosphamide44 50 1110.9NOS3, THBD, VEGFA, SOD2, SST, CCL2
7bleomycin44 119.8FGF2, NOS3, CCL2, EPO, SOD2
8thalidomide44 50 61 1111.8EPO, FGF2, IL6, VEGFA, THBD
9ang ii448.7NOS3, DYT10, CCL2, REN, VEGFA
10fluvastatin44 50 28 1111.7IL6, NOS3, CCL2, THBD, ICAM1
11nadph44 249.7THBD, SERPINF1, SOD2, PRKCB, CCL2, NOS3
1215-deoxy-delta-12,14-prostaglandin j2448.7CCL2, NOS3, FGF2, IL6, VEGFA
13atorvastatin44 50 28 24 1112.6NOS3, IL6, THBD, VEGFA, CCL2, ICAM1
14prostacyclin448.6CCL2, ICAM1, NOS3, REN, FGF2, VEGFA
15curcumin448.6THBD, IL6, AKR1B1, VEGFA, ICAM1, CCL2
16ascorbic acid44 249.6EPO, THBD, NOS3, SOD2, AKR1B1, FGF2
17simvastatin44 50 61 28 24 1113.5THBD, VEGFA, ICAM1, CCL2, IL6, NOS3
18calcitriol44 61 24 1111.5PRKCB, SOD2, THBD, IL6, EPO, REN
19fenofibrate44 50 1110.5NOS3, INS, IL6, ICAM1, CCL2
20gf 109203x44 619.5PRKCB, VEGFA, DYT10, FGF2, SOD2, NOS3
21polymyxin b448.5IL6, THBD, DYT10, CCL2, ICAM1
22hydrocortisone44 2 61 1111.4EPO, REN, INS, FGF2, IL6, SST
238-isoprostane448.3THBD, ICAM1, IL6, CCL2, NOS3, INS
24pravastatin44 50 28 24 1112.3CCL2, NOS3, IL6, ICAM1, THBD
25vitamin d448.3THBD, SOD2, EPO, IL6, PRKCB, CCL2
26matrigel448.3NOS3, THBD, ICAM1, FGF2, SERPINF1, VEGFA
27pdtc448.3SOD2, ICAM1, CCL2, IL6, DYT10
28epinephrine44 24 1110.2INS, SOD2, AKR1B1, REN, SST, IL6
29diphenyleneiodonium448.2SOD2, ICAM1, CCL2, VEGFA, DYT10, SERPINF1
30norepinephrine44 24 1110.2REN, AKR1B1, SOD2, INS, SST, CCL2
31cyclosporin a44 28 6110.2SOD2, THBD, ICAM1, PRKCB, IL6, AKR1B1
32gnrh448.1DYT10, CCL2, SST, PRKCB, EPO, INS
33lactate448.0THBD, AKR1B1, EPO, SOD2, INS, ICAM1
34arginine447.8INS, SOD2, AKR1B1, REN, SST, NOS3
35nitric oxide44 24 119.8CCL2, REN, IL6, PRKCB, SOD2, THBD
36n acetylcysteine447.8CCL2, ICAM1, AKR1B1, SERPINF1, SOD2, IL6
37creatinine447.8INS, AKR1B1, EPO, IL6, CCL2, REN
38h2o2447.8FGF2, SERPINF1, SOD2, THBD, AKR1B1, ICAM1
39glucose447.8SERPINF1, IL6, CCL2, THBD, INS, PRKCB
40sb 20358044 618.6VEGFA, FGF2, NOS3, DYT10, IL6, CCL2
41retinoic acid44 248.1THBD, SERPINF1, PRKCB, ICAM1, SST, DYT10
42dexamethasone44 50 28 1110.1FGF2, THBD, INS, IL6, CCL2, SST
43pge2447.1AKR1B1, REN, ICAM1, SST, VEGFA, IL6
44cycloheximide447.0VEGFA, THBD, SOD2, AKR1B1, ICAM1, SST
45phosphatidylinositol447.0NOS3, INS, EPO, PRKCB, ICAM1, CCL2
46actinomycin d446.9CCL2, IL6, DYT10, NOS3, FGF2, ICAM1
47genistein44 28 61 2 24 1111.9CCL2, VEGFA, SST, SOD2, NOS3, AKR1B1
48tyrosine446.6VEGFA, FGF2, DYT10, IL6, ICAM1, PRKCB
49ly294002446.6DYT10, ICAM1, INS, VEGFA, SOD2, EPO
50vegf445.6VEGFA, THBD, SERPINF1, EPO, DYT10, NOS3

GO Terms for genes affiliated with Diabetic Macular Edema

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Cellular components related to Diabetic Macular Edema according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055767.2IL6, CCL2, SST, REN, EPO, SERPINF1
2extracellular spaceGO:0056156.1THBD, SST, ICAM1, REN, AKR1B1, EPO

Biological processes related to Diabetic Macular Edema according to GeneCards/GeneDecks:

(show all 37)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of vascular endothelial growth factor receptor signaling pathwayGO:03094910.2PRKCB, VEGFA
2C21-steroid hormone biosynthetic processGO:00670010.1FGF2, AKR1B1
3kidney developmentGO:00182210.1SERPINF1, REN, VEGFA
4response to hyperoxiaGO:05509310.1EPO, SOD2
5negative regulation of platelet activationGO:01054410.0NOS3, THBD
6cell migration involved in sprouting angiogenesisGO:00204210.0VEGFA, FGF2
7positive regulation of protein autophosphorylationGO:0319549.9INS, VEGFA
8negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stressGO:19021769.9INS, SOD2
9positive regulation of blood vessel endothelial cell migrationGO:0435369.9VEGFA, FGF2
10negative regulation of calcium ion transportGO:0519269.9ICAM1, NOS3
11cellular response to hypoxiaGO:0714569.9VEGFA, EPO, ICAM1
12response to axon injuryGO:0486789.8SOD2, EPO, FGF2
13regulation of vascular endothelial growth factor productionGO:0105749.8CCL2, IL6
14positive regulation of endothelial cell proliferationGO:0019389.8FGF2, CCL2, VEGFA
15regulation of blood pressureGO:0082179.8SOD2, REN, NOS3
16lung developmentGO:0303249.7NOS3, VEGFA, FGF2
17response to electrical stimulusGO:0516029.6IL6, EPO, SOD2
18negative regulation of gluconeogenesisGO:0457219.6INS, IL6
19response to glucocorticoidGO:0513849.6CCL2, SERPINF1, IL6
20monocyte chemotaxisGO:0025489.6IL6, CCL2
21vascular endothelial growth factor receptor signaling pathwayGO:0480109.6CCL2, VEGFA
22positive regulation of angiogenesisGO:0457669.6NOS3, VEGFA, PRKCB, FGF2
23response to hypoxiaGO:0016669.5CCL2, VEGFA, SOD2
24regulation of angiogenesisGO:0457659.4IL6, FGF2
25positive regulation of DNA replicationGO:0457409.4INS, EPO, IL6
26agingGO:0075689.3CCL2, IL6, EPO, SERPINF1
27blood coagulationGO:0075969.3THBD, NOS3, VEGFA, PRKCB
28regulation of cell shapeGO:0083609.3IL6, CCL2, VEGFA, ICAM1
29response to amino acidGO:0432009.3ICAM1, IL6, CCL2, SST
30positive regulation of peptidyl-tyrosine phosphorylationGO:0507319.2INS, IL6, ICAM1, VEGFA
31positive regulation of NF-kappaB transcription factor activityGO:0510929.1IL6, ICAM1, PRKCB, INS
32response to lipopolysaccharideGO:0324969.1SOD2, REN, IL6, THBD, EPO
33response to heatGO:0094089.1CCL2, NOS3, SST, IL6
34positive regulation of nitric oxide biosynthetic processGO:0454299.1ICAM1, SOD2, IL6, INS
35response to drugGO:0424938.9SST, IL6, CCL2, ICAM1, SOD2
36negative regulation of cell proliferationGO:0082858.8SOD2, FGF2, NOS3, SST, IL6
37positive regulation of cell proliferationGO:0082848.7FGF2, INS, IL6, EPO, VEGFA

Molecular functions related to Diabetic Macular Edema according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1chemoattractant activityGO:0420569.8FGF2, VEGFA
2insulin-like growth factor receptor bindingGO:0051599.8REN, INS
3heparin bindingGO:0082019.5CCL2, VEGFA, FGF2
4hormone activityGO:0051799.4INS, EPO, SST
5cytokine activityGO:0051259.2VEGFA, IL6, FGF2
6growth factor activityGO:0080838.9IL6, VEGFA, FGF2
7protein bindingGO:0055156.5CEP135, THBD, INS, VEGFA, EPO, PRKCB

Products for genes affiliated with Diabetic Macular Edema

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Sources for Diabetic Macular Edema

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet