MCID: DRR001
MIFTS: 60

Diarrhea

Categories: Rare diseases, Gastrointestinal diseases, Genetic diseases

Aliases & Classifications for Diarrhea

MalaCards integrated aliases for Diarrhea:

Name: Diarrhea 12 28 40 41 14
Diarrhea of Presumed Infectious Origin 12
Diarrhoea 12

Classifications:



Summaries for Diarrhea

MedlinePlus : 40 What is diarrhea? Diarrhea is loose, watery stools (bowel movements). You have diarrhea if you have loose stools three or more times in one day. Acute diarrhea is diarrhea that lasts a short time. It is a common problem. It usually lasts about one or two days, but it may last longer. Then it goes away on its own. Diarrhea lasting more than a few days may be a sign of a more serious problem. Chronic diarrhea -- diarrhea that lasts at least four weeks -- can be a symptom of a chronic disease. Chronic diarrhea symptoms may be continual, or they may come and go. Who gets diarrhea? People of all ages can get diarrhea. On average, adults In the United States have acute diarrhea once a year. Young children have it an average of twice a year. People who visit developing countries are at risk for traveler's diarrhea. It is caused by consuming contaminated food or water. What causes diarrhea? The most common causes of diarrhea include Bacteria from contaminated food or water Viruses such as the flu, norovirus, or rotavirus . Rotavirus is the most common cause of acute diarrhea in children. Parasites, which are tiny organisms found in contaminated food or water Medicines such as antibiotics, cancer drugs, and antacids that contain magnesium Food intolerances and sensitivities, which are problems digesting certain ingredients or foods. An example is lactose intolerance. Diseases that affect the stomach, small intestine, or colon, such as Crohn's disease Problems with how the colon functions, such as irritable bowel syndrome Some people also get diarrhea after stomach surgery, because sometimes the surgeries can cause food to move through your digestive system more quickly. Sometimes no cause can be found. If your diarrhea goes away within a few days, finding the cause is usually not necessary. What other symptoms might I have with diarrhea? Other possible symptoms of diarrhea include Cramps or pain in the abdomen An urgent need to use the bathroom Loss of bowel control If a virus or bacteria is the cause of your diarrhea, you may also have a fever, chills, and bloody stools. Diarrhea can cause dehydration, which means that your body does not have enough fluid to work properly. Dehydration can be serious, especially for children, older adults, and people with weakened immune systems. When should I see a doctor for diarrhea? Although it is usually not harmful, diarrhea can become dangerous or signal a more serious problem. Contact your health care provider if you have Signs of dehydration Diarrhea for more than 2 days, if you are an adult. For children, contact the provider if it lasts more than 24 hours. Severe pain in your abdomen or rectum (for adults) A fever of 102 degrees or higher Stools containing blood or pus Stools that are black and tarry If children have diarrhea, parents or caregivers should not hesitate to call a health care provider. Diarrhea can be especially dangerous in newborns and infants. How is the cause of diarrhea diagnosed? To find the cause of diarrhea, your health care provider may Do a physical exam Ask about any medicines you are taking Test your stool or blood to look for bacteria, parasites, or other signs of disease or infection Ask you to stop eating certain foods to see whether your diarrhea goes away If you have chronic diarrhea, your health care provider may perform other tests to look for signs of disease. What are the treatments for diarrhea? Diarrhea is treated by replacing lost fluids and electrolytes to prevent dehydration. Depending on the cause of the problem, you may need medicines to stop the diarrhea or treat an infection. Adults with diarrhea should drink water, fruit juices, sports drinks, sodas without caffeine, and salty broths. As your symptoms improve, you can eat soft, bland food. Children with diarrhea should be given oral rehydration solutions to replace lost fluids and electrolytes. Can diarrhea be prevented? Two types of diarrhea can be prevented - rotavirus diarrhea and traveler's diarrhea. There are vaccines for rotavirus. They are given to babies in two or three doses. You can help prevent traveler's diarrhea by being careful about what you eat and drink when you are in developing countries: Use only bottled or purified water for drinking, making ice cubes, and brushing your teeth If you do use tap water, boil it or use iodine tablets Make sure that the cooked food you eat is fully cooked and served hot Avoid unwashed or unpeeled raw fruits and vegetables NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Diarrhea, also known as diarrhea of presumed infectious origin, is related to diarrhea 8, secretory sodium, congenital and diarrhea 1, secretory chloride, congenital. An important gene associated with Diarrhea is SLC26A3 (Solute Carrier Family 26 Member 3), and among its related pathways/superpathways are Dasatinib Pathway, Pharmacokinetics and Zidovudine Pathway, Pharmacokinetics/Pharmacodynamics. The drugs Ceftriaxone and Sucralfate have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and lung, and related phenotypes are digestive/alimentary and homeostasis/metabolism

Disease Ontology : 12 A gastrointestinal system disease described as the condition of having frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause severe dehydration which is one cause of death in diarrhea sufferers. Along with water, sufferers also lose dangerous amounts of important salts, electrolytes, and other nutrients. There are at least four types of diarrhea

Wikipedia : 72 Diarrhea, also spelled diarrhoea, is the condition of having at least three loose or liquid bowel... more...

Related Diseases for Diarrhea

Diseases in the Diarrhea family:

Diarrhea 6 Diarrhea 7
Chronic Diarrhea Due to Guanylate Cyclase 2c Overactivity Inflammatory Diarrhea
Acute Diarrhea Congenital Diarrhea

Diseases related to Diarrhea via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 557)
# Related Disease Score Top Affiliating Genes
1 diarrhea 8, secretory sodium, congenital 34.3 SLC9A3 SPINT2
2 diarrhea 1, secretory chloride, congenital 34.2 SLC26A3 SLC9A3
3 osmotic diarrhea 34.1 MME SLC26A3 SLC9A3
4 diarrhea 5, with tufting enteropathy, congenital 34.0 EPCAM MYO5B NEUROG3 SPINT2
5 diarrhea 2, with microvillus atrophy 34.0 MYO5B SKIV2L SLC26A3 SLC9A3 TTC37
6 trichohepatoenteric syndrome 1 33.9 SKIV2L TTC37
7 secretory diarrhea 33.4 FOXP3 GUCY2C MYO5B SLC26A3 SLC9A3 SPINT2
8 congenital diarrhea 33.3 DGAT1 EPCAM MYO5B NEUROG3 SKIV2L SLC9A3
9 celiac disease 1 32.0 CCK CD40LG FOXP3
10 pancreatitis 31.9 CCK SST TMPRSS15
11 steatorrhea 30.5 CCK SST TMPRSS15
12 pancreatic cholera 29.8 CCK SST
13 acute pancreatitis 29.8 CCK SST TMPRSS15
14 gastrointestinal system disease 29.7 CCK CD40LG SST
15 diarrhea 3, secretory sodium, congenital, with or without other congenital anomalies 12.3
16 congenital chloride diarrhea 12.3
17 diarrhea 4, malabsorptive, congenital 12.3
18 acute diarrhea 12.3
19 diarrhea 6 12.2
20 chronic diarrhea due to guanylate cyclase 2c overactivity 12.2
21 inflammatory diarrhea 12.1
22 diarrhea 7 12.1
23 congenital diarrhea 7 with exudative enteropathy 12.1
24 functional diarrhea 12.0
25 motility-related diarrhea 12.0
26 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 11.8
27 diarrhea, chronic, with villous atrophy 11.8
28 secretory diarrhea, myopathy, and deafness 11.8
29 dysentery 11.8
30 diarrhea, glucose-stimulated secretory, with common variable immunodeficiency 11.8
31 intractable diarrhea-choanal atresia-eye anomalies syndrome 11.8
32 chronic diarrhea due to glucoamylase deficiency 11.8
33 satoyoshi syndrome 11.6
34 hemolytic uremic syndrome, atypical 1 11.6
35 vipoma 11.5
36 cholera 11.4
37 cryptosporidiosis 11.3
38 hemolytic uremic syndrome, atypical 2 11.3
39 hemolytic uremic syndrome, atypical 3 11.3
40 hemolytic uremic syndrome, atypical 4 11.3
41 hemolytic uremic syndrome, atypical 5 11.3
42 hemolytic uremic syndrome, atypical 6 11.3
43 gastroenteritis 11.2
44 irritable bowel syndrome 11.2
45 shigellosis 11.2
46 chylomicron retention disease 11.1
47 lactose intolerance 11.1
48 wdha syndrome 11.1
49 hemolytic-uremic syndrome 11.1
50 acrodermatitis enteropathica, zinc-deficiency type 11.1

Graphical network of the top 20 diseases related to Diarrhea:



Diseases related to Diarrhea

Symptoms & Phenotypes for Diarrhea

MGI Mouse Phenotypes related to Diarrhea:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 10.02 ABCB1 DGAT1 EPCAM FOXP3 GUCY2C MYO5B
2 homeostasis/metabolism MP:0005376 10 ABCB1 CCK CD40LG DGAT1 EPCAM FOXP3
3 endocrine/exocrine gland MP:0005379 9.91 CD40LG DGAT1 EPCAM FOXP3 NEUROG3 SLC26A3
4 mortality/aging MP:0010768 9.73 ABCB1 ANTXR2 CD40LG EPCAM FOXP3 GUCY2C
5 no phenotypic analysis MP:0003012 9.17 ABCB1 ANTXR2 CCK EPCAM FOXP3 NEUROG3

Drugs & Therapeutics for Diarrhea

Drugs for Diarrhea (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 929)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
2
Sucralfate Approved Phase 4 54182-58-0 0
3
Carboprost Tromethamine Approved Phase 4 58551-69-2 45266502 5284525
4
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 5311068 56032 68602
5 Ramosetron Approved, Investigational Phase 4,Phase 3,Phase 2 132036-88-5
6
Glyburide Approved Phase 4,Phase 3 10238-21-8 3488
7
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 73590-58-6 4594
8
Diltiazem Approved, Investigational Phase 4 42399-41-7 39186
9
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1 93-14-1 3516
10
Methadone Approved Phase 4,Phase 1 76-99-3 4095
11
Metformin Approved Phase 4,Phase 3,Phase 2,Early Phase 1 657-24-9 4091 14219
12
Exenatide Approved, Investigational Phase 4 141758-74-9 15991534
13
Insulin Glargine Approved Phase 4,Phase 3 160337-95-1
14
Insulin Lispro Approved Phase 4,Phase 3 133107-64-9
15
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
16
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
17
Ticlopidine Approved Phase 4 55142-85-3 5472
18
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 26787-78-0 33613 2171
19
Bisoprolol Approved Phase 4 66722-44-9 2405
20
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
21
Norepinephrine Approved Phase 4 51-41-2 439260
22
Zinc Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 7440-66-6 32051 23994
23
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 1994-09-7, 94-09-7 2337
24
Loperamide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 53179-11-6 3955
25 Zinc sulfate Approved, Investigational Phase 4,Phase 2,Phase 3 7733-02-0
26
Rifaximin Approved, Investigational Phase 4,Phase 3,Phase 2 80621-81-4 6436173
27
Ondansetron Approved Phase 4,Phase 3,Phase 2 99614-02-5 4595
28
Iron Approved Phase 4,Phase 3,Phase 2,Early Phase 1 7439-89-6 23925
29
Iodine Approved, Investigational Phase 4,Phase 3,Phase 2 7553-56-2 807
30
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 85721-33-1 2764
31
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-02-2 5743
32
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
33
Metoclopramide Approved, Investigational Phase 4,Phase 3 364-62-5 4168
34
Fluorouracil Approved Phase 4,Phase 3,Phase 2,Phase 1 51-21-8 3385
35
Oxaliplatin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 61825-94-3 43805 6857599 5310940 9887054
36
Budesonide Approved Phase 4,Phase 3,Phase 2 51333-22-3 5281004 63006
37
Capecitabine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 154361-50-9 60953
38
Irinotecan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 97682-44-5, 100286-90-6 60838
39
Vancomycin Approved Phase 4,Phase 3,Phase 2,Phase 1 1404-90-6 14969 441141
40 Pinaverium Approved Phase 4 59995-65-2
41
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2 564-25-0 54671203
42
Misoprostol Approved Phase 4,Phase 2,Phase 3 59122-46-2 5282381
43
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1 443-48-1 4173
44
Infliximab Approved Phase 4,Phase 2,Phase 1 170277-31-3
45
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
46
Albendazole Approved, Vet_approved Phase 4,Phase 2 54965-21-8 2082
47
Azithromycin Approved Phase 4,Phase 3,Phase 2,Phase 1 83905-01-5 53477736 447043 55185
48 Simethicone Approved Phase 4,Phase 3
49
Eluxadoline Approved, Investigational Phase 4,Phase 2 864821-90-9
50
Octreotide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 83150-76-9 6400441 383414

Interventional clinical trials:

(show top 50) (show all 1782)

# Name Status NCT ID Phase Drugs
1 Lactobacillus Preparation on the Incidence of Diarrhea Unknown status NCT01792739 Phase 4 Lactobacillus casei variety rhamnosus granules;Placebo
2 Saccharomyces Boulardii in Diarrhea Dominant Irritable Bowel Syndrome Unknown status NCT00543478 Phase 4 Saccharomyces boulardii;Methyl cellulose powder (low viscosity)
3 Prophylaxis of Gastrointestinal Infections With EcN Unknown status NCT01469273 Phase 4 Mutaflor® Suspension
4 The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis Unknown status NCT01278017 Phase 4 ceftriaxone
5 ZeroTolerance Mucositis: Managing Oral and Alimentary Mucositis With High Potency Sucralfate - ProThelial Unknown status NCT02016807 Phase 4
6 Anti-inflammatory Effect of Atorvastatin in Atherosclerotic Plaques Assessed by FDG-PET Imaging Unknown status NCT00920101 Phase 4 Atorvastatin
7 Dexmedetomidine on Prevention of Side Effects of Hemabate Unknown status NCT02220361 Phase 4 placebo;low dose dexmedetomidine;high dose dexmedetomidine
8 The Effect of Probiotics on Exacerbation of Inflammatory Bowel Disease Exacerbation (Crohn's Disease) Unknown status NCT01765998 Phase 4 Probiotic;Placebo
9 Effect of Ramosetron on Bowel Motility After Colorectal Resection Unknown status NCT01427127 Phase 4 Ramosetron
10 Long-Term Sulfonylurea Response in ABCC8 Neonatal Diabetes (SuResponsSUR) Unknown status NCT02624830 Phase 4 Sulfonylurea
11 Strategy to Improve Adherence of Roflumilast Unknown status NCT02018432 Phase 4 Roflumilast escalation dosage;Roflumilast conventional dosage
12 Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD) Unknown status NCT01822106 Phase 4
13 Pediatrics Anal Fissures Treatment With Polyethylene Glycol Unknown status NCT02419534 Phase 4 Polyethylene glycol;Polyethylene glycol with Diltiazem
14 Adjunct Methadone to Decrease the Duration of Mechanical Ventilation in the Medical Intensive Care Unit Unknown status NCT02025855 Phase 4 Methadone;Placebo
15 Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission Unknown status NCT01901666 Phase 4 Growth Hormone
16 Manipulation of Visceral Sensitivity and Immune System in IBS Unknown status NCT00418340 Phase 4 probiotic (bacterial/dietary supplement)
17 Metformin for Weight Control in Adolescents Taking Atypical Antipsychotics Unknown status NCT00845936 Phase 4 Metformin
18 Effect of Exenatide on 24h-UAER in Patients With Diabetic Nephropathy Unknown status NCT02690883 Phase 4 Exenatide;Lispro
19 The Efficacy of Hydrolyzed Guar Gum ( PHGG) in the Treatment of Patients With Irritable Bowel Syndrome (IBS) Unknown status NCT01779765 Phase 4
20 Medical and Endovascular Treatment of Atherosclerotic Renal Artery Stenosis (METRAS Study) Unknown status NCT01208714 Phase 4 Optimal medical therapy
21 Middle Meatal Bacteriology During Acute Respiratory Infection in Children Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
22 BRAVE Study With Uncontrolled Essential Hypertension (BRAVE Study) Unknown status NCT02398929 Phase 4 Bisoprolol 2.5 mg;Placebo
23 Ambulatory Oxygen in Fibrotic Lung Disease (FLD) (AmbOx) Unknown status NCT02286063 Phase 4 Ambulatory Oxygen
24 Neurochemical, Metabonomics and Neuroimaging Characterization of TCM Diagnostic Subtypes of Major Depression Disorder Unknown status NCT02346682 Phase 4 venlafaxine
25 Effects of Probiotics and/or Prebiotics on the Duration of Diarrhea and Hospitalization in Children Completed NCT01927094 Phase 4
26 Community Based Intervention and Evaluation of the Impact of Social Marketing of a Diarrhea Management Pack Completed NCT00942812 Phase 4
27 Oral Administration of Tannins and Flavonoids in Children With Acute Diarrhea Completed NCT03356327 Phase 4 Actitan F;Standard Oral Rehydration
28 Use of Probiotic Yogurt in the Treatment of Acute Diarrhea in Children Completed NCT01564290 Phase 4 Placebo probiotic
29 Preventing Antibiotic-Associated DiarRhea Using Erceflora Completed NCT00447161 Phase 4 Bacillus Clausii Multi ATB Resist;Placebo
30 Azithromycin, With or Without Loperamide, to Treat Travelers' Diarrhea Completed NCT00359970 Phase 4 Azithromycin 500 mg;Azithromycin 1000 mg;Loperamide
31 Mesalazine for the Treatment of Diarrhoea-predominant Irritable Bowel Syndrome (IBS-D) Completed NCT01316718 Phase 4 Mesalazine;Placebo
32 Probiotics at the Treatment of Antibiotic Associated Diarrhea Completed NCT00700557 Phase 4
33 Efficacy of Racecadotril in Acute Watery Diarrhea in Children Completed NCT01577043 Phase 4 Racecadotril
34 A Comparison of Three Medications to Treat Diarrhea in Adults. Completed NCT00807326 Phase 4 Loperamide/simeticone 2 mg/125 mg caplets;Loperamide/simeticone 2 mg/125 mg chewable tablets;Probiotic Saccharomyces boulardii 250 mg capsules
35 Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants Completed NCT01571856 Phase 4 Zinc Sulfate
36 Efficacy of Lactobacillus GG With Diosmectite in Treatment Children With Acute Gastroenteritis Completed NCT01657032 Phase 4
37 Rifaximin, Loperamide and the Combination to Treat Travelers' Diarrhea Completed NCT00292344 Phase 4 Rifaximin and loperamide
38 Study to Evaluate Smecta® vs Placebo on the Time to Recovery Following an Acute Diarrhoea Episode in Adults Completed NCT00276328 Phase 4 Diosmectite (Smecta®)
39 Efficacy of Eluxadoline in the Treatment of Irritable Bowel Syndrome With Diarrhea in Patients With Inadequate Control of Symptoms With Prior Loperamide Use Completed NCT02959983 Phase 4 Eluxadoline;Placebo
40 Ondansetron for the Treatment of IBS With Diarrhoea (IBS-D) Completed NCT00745004 Phase 4 Ondansetron;Placebo
41 Study to Determine the Best Way to Measure How Quickly the Drug Can Give Relief From Sudden Diarrhea Completed NCT00685607 Phase 4 loperamide-simethicone;matching placebo
42 Evaluation Of Bacillus Clausii In Treatment Of Acute Diarrhea In Latin American Children Completed NCT02169817 Phase 4 Bacillus clausii;Oral Rehydration Therapy
43 Rifaximin for Preventing Relapse of Clostridium Associated Diarrhoea Completed NCT01670149 Phase 4 Rifaximin;Placebo
44 STOP Trial - Sandostatin LAR Depot Trial for the Optimum Prevention of Chemotherapy Induced Diarrhea Completed NCT00050635 Phase 4 Sandostatin LAR Depot
45 New Hypo-Osmolar ORS (Recommended by WHO) for Routine Use in the Diarrhea Management– Surveillance Study for Adverse Effects Completed NCT00490932 Phase 4 Hypo-osmolar ORS
46 Validation of Stimulated ∆FGF19 for Diagnosing Bile Acid Diarrhoea Completed NCT03059537 Phase 4 Oral chenodeoxycholic acid stimulation
47 A Study to Evaluate Efficacy of Ramosetron on Diarrhea-predominant Irritable Bowel Syndrome (IBS) in Male Patients Completed NCT01225237 Phase 4 Ramosetron;Placebo
48 A Preliminary Study to Explore Clinical Endpoints in Patients (Male) With Diarrhea-predominant Irritable Bowel Syndrome Completed NCT00918411 Phase 4 Ramosetron;Placebo
49 Efficacy and Safety of a New Oral Rehydration Solution (Hipp ORS 200 Apple) in Children With Acute Gastroenteritis Completed NCT01467570 Phase 4
50 Ability of Mayo Clinic High-performance Liquid Chromatography (HPLC) Method to Measure Fecal Bile Acids Completed NCT02111603 Phase 4 Colesevelam

Search NIH Clinical Center for Diarrhea

Cochrane evidence based reviews: diarrhea

Genetic Tests for Diarrhea

Genetic tests related to Diarrhea:

# Genetic test Affiliating Genes
1 Diarrhea 28

Anatomical Context for Diarrhea

MalaCards organs/tissues related to Diarrhea:

38
Colon, Testes, Lung, Kidney, Heart, Liver, Prostate

Publications for Diarrhea

Articles related to Diarrhea:

(show top 50) (show all 2046)
# Title Authors Year
1
Chronic Diarrhea in Common Variable Immunodeficiency: a Case Series and Review of the Literature. ( 29138951 )
2018
2
Efficacy and safety of Modified Tongxie Yaofang in diarrhea-predominant irritable bowel syndrome management: A meta-analysis of randomized, positive medicine-controlled trials. ( 29408906 )
2018
3
Short communication: Calf cleanliness does not predict diarrhea upon arrival at a veal calf facility. ( 29428765 )
2018
4
The other Campylobacters: Not innocent bystanders in endemic diarrhea and dysentery in children in low income settings. ( 29415075 )
2018
5
Complete Genome Sequence of a Recombinant Porcine Epidemic Diarrhea Virus Strain, CH/JXJA/2017, Isolated in Jiangxi, China, in 2017. ( 29439052 )
2018
6
Cost-effectiveness analysis of telotristat ethyl for treatment of carcinoid syndrome diarrhea inadequately controlled with somatostatin analogs. ( 28959913 )
2018
7
Loss-of-Function Mutations in UNC45A Cause a Syndrome Associating Cholestasis, Diarrhea, Impaired Hearing, and Bone Fragility. ( 29429573 )
2018
8
The effect of Clostridium butyricum on symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. ( 29445178 )
2018
9
Bta-miR-2411 attenuates bovine viral diarrhea virus replication via directly suppressing Pelota protein in Madin-Darby bovine kidney cells. ( 29426405 )
2018
10
Diagnosis and Treatment of Undifferentiated and Infectious Acute Diarrhea in the Adult Horse. ( 29426709 )
2018
11
Development of a TaqMan-based real-time RT-PCR assay for the detection of SADS-CoV associated with severe diarrhea disease in pigs. ( 29427670 )
2018
12
Telotristat ethyl: a novel agent for the therapy of carcinoid syndrome diarrhea. ( 29350062 )
2018
13
Diagnostics and Treatments in Chronic Diarrhea and Weight Loss in Horses. ( 29426710 )
2018
14
New Insights into<i>Clostridium difficile</i>(CD) Infection in Latin America: Novel Description of Toxigenic Profiles of Diarrhea-Associated to CD in BogotA!, Colombia. ( 29441053 )
2018
15
The prevalence of celiac disease in adult Chinese patients with diarrhea predominant irritable bowel syndrome of China, a prospective, controlled, cohort study. ( 29451364 )
2018
16
Prevalence and Molecular Characterization of<i>Campylobacter</i>spp. Isolated from Patients with Diarrhea in Shunyi, Beijing. ( 29434579 )
2018
17
Extracellular Calcium Dictates Onset, Severity, and Recovery of Diarrhea in a Child with Immune-Mediated Enteropathy. ( 29435439 )
2018
18
Stability of Porcine Epidemic Diarrhea Virus on Fomite Materials at Different Temperatures. ( 29438310 )
2018
19
A traumatic hepatic artery pseudoaneurysm and arterioportal fistula, with severe diarrhea as the first symptom: A case report and review of the literature. ( 29443759 )
2018
20
Characteristics of diarrheagenic Escherichia coli among children under 5 years of age with acute diarrhea: a hospital based study. ( 29390982 )
2018
21
Schistosomiasis in a returning international traveler with cyclic fevers and diarrhea. ( 29449243 )
2018
22
Differences in the intestinal microbiota between uninfected piglets and piglets infected with porcine epidemic diarrhea virus. ( 29447243 )
2018
23
Incidence of Acute Diarrhea-Associated Death among Children < 5 Years of Age in Bangladesh, 2010-12. ( 29141756 )
2018
24
Advancements in drug development for diarrhea-predominant irritable bowel syndrome. ( 29451407 )
2018
25
Hospital-based surveillance for rotavirus diarrhea in Ulaanbaatar, Mongolia, April 2009 through March 2016. ( 29429811 )
2018
26
Prospective study on the overuse of blood test-guided antibiotics on patients with acute diarrhea in primary hospitals of China. ( 28352160 )
2017
27
Acute kidney injury following vomiting and diarrhea after endoscopy in a duodenal gastrinoma patient. ( 28070096 )
2017
28
Pre-vaccine circulating group a rotavirus strains in under 5 years children with acute diarrhea during 1999-2013 in Cameroon. ( 29051924 )
2017
29
Serum Zinc Level and Its Correlation with Vesikari System Scoring in Acute Pediatric Diarrhea. ( 28932313 )
2017
30
Prevalence of lactose intolerance in patients with diarrhea-predominant irritable bowel syndrome: data from a tertiary center in southern China. ( 29157302 )
2017
31
Chronic Diarrhea and Metabolic Acidosis Associated With Topiramate Use. ( 28885991 )
2017
32
Sanitation facilities, hygienic conditions, and prevalence of acute diarrhea among under-five children in slums of Addis Ababa, Ethiopia: Baseline survey of a longitudinal study. ( 28854200 )
2017
33
Antibiotic Therapy for Acute Watery Diarrhea and Dysentery. ( 28885920 )
2017
34
Blood urea nitrogen to serum creatinine ratio as a prognostic factor in diarrhea-associated hemolytic uremic syndrome: a validation study. ( 28831612 )
2017
35
Secretome analysis of diarrhea-inducing strains of Escherichia coli. ( 28070933 )
2017
36
Prolonged intestinal transit and diarrhea in patients with an activating GUCY2C mutation. ( 28957388 )
2017
37
Ameliorative effects of atractylodin on intestinal inflammation and co-occurring dysmotility in both constipation and diarrhea prominent rats. ( 28066135 )
2017
38
A cross-sectional study of acute diarrhea in Pudong, Shanghai, China: prevalence, risk factors, and healthcare-seeking practices. ( 28830575 )
2017
39
Effectiveness of probiotics in reducing the incidence of Clostridium difficile-associated diarrhea in elderly patients: a systematic review. ( 28085732 )
2017
40
Cryptosporidium Species are Frequently Present but Rarely Detected in Clinical Samples from Children with Diarrhea in a Developed Country. ( 28938260 )
2017
41
Disseminated cat-scratch disease presenting as nausea, diarrhea, and weight loss without fever in a heart transplant recipient. ( 28199763 )
2017
42
Prevalence and determinants of acute diarrhea among children younger than five years old in Jabithennan District, Northwest Ethiopia, 2014. ( 28103908 )
2017
43
The place of eluxadoline in the management of irritable bowel syndrome with diarrhea. ( 28932272 )
2017
44
The Most Important Recommended Times of Hand Washing with Soap and Water in Preventing the Occurrence of Acute Diarrhea Among Children Under Five Years of Age in Slums of Addis Ababa, Ethiopia. ( 29138957 )
2017
45
Telotristat ethyl (Xermelo) for carcinoid syndrome diarrhea. ( 28699933 )
2017
46
A Surprising Case of Acute Diarrhea in the South of France. ( 27893974 )
2017
47
Influence of border disease virus (BDV) on serological surveillance within the bovine virus diarrhea (BVD) eradication program in Switzerland. ( 28086880 )
2017
48
Organic Solute Transporter-beta (SLC51B) Deficiency in Two Brothers with Congenital Diarrhea and Features of Cholestasis. ( 28898457 )
2017
49
Incidence and management of diarrhea in patients with HER2-positive breast cancer treated with pertuzumab. ( 28057664 )
2017
50
Impact of Childhood Nutritional Status on Pathogen Prevalence and Severity of Acute Diarrhea. ( 29140236 )
2017

Variations for Diarrhea

Expression for Diarrhea

Search GEO for disease gene expression data for Diarrhea.

Pathways for Diarrhea

GO Terms for Diarrhea

Cellular components related to Diarrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.65 ABCB1 ANTXR2 CD40LG EPCAM SLC9A3
2 apical plasma membrane GO:0016324 9.55 ABCB1 EPCAM SI SLC26A3 SLC9A3
3 Ski complex GO:0055087 8.96 SKIV2L TTC37
4 brush border GO:0005903 8.92 MME SI SLC9A3 TMPRSS15
5 integral component of membrane GO:0016021 10.13 ABCB1 ANTXR2 CD40LG CYP3A4 DGAT1 EPCAM

Biological processes related to Diarrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of interleukin-4 production GO:0032753 8.62 CD40LG FOXP3

Sources for Diarrhea

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
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43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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