MCID: DFF019
MIFTS: 53

Diffuse Gastric Cancer malady

Genetic diseases, Rare diseases, Gastrointestinal diseases, Cancer diseases categories
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Summaries for Diffuse Gastric Cancer

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43NIH Rare Diseases, 33MalaCards
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NIH Rare Diseases:43 Diffuse gastric cancer is a type of cancer found most often in the glandular cells lining the stomach, but can also develop in the bowel, breast, pancreas, bladder, prostate or lung. the term "signet ring cell" is often used because the cells look like signet rings when viewed under a microscope. the signet cells are a type of epithelial cell. epithelial tissue is skin tissue, covering and lining the body both inside and out.  last updated: 12/16/2011

MalaCards: Diffuse Gastric Cancer, also known as signet ring cell gastric carcinoma, is related to hereditary diffuse gastric cancer and tubular adenocarcinoma. An important gene associated with Diffuse Gastric Cancer is CDH1 (cadherin 1, type 1, E-cadherin (epithelial)), and among its related pathways are E-cadherin signaling in keratinocytes and Signaling by Interleukins. The compounds vinylchloride and chi 2 have been mentioned in the context of this disorder. Affiliated tissues include breast, lung and pancreas, and related mouse phenotypes are skeleton and immune system.

Aliases & Classifications for Diffuse Gastric Cancer

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43NIH Rare Diseases, 62UMLS
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Classifications:



Aliases & Descriptions:

diffuse gastric cancer 43
signet ring cell gastric carcinoma 43
signet ring gastric carcinoma 43
carcinoma, signet ring cell 62
signet ring cell carcinoma 43
signet cell adenocarcinoma 43


Related Diseases for Diffuse Gastric Cancer

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17GeneCards, 18GeneDecks
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Diseases in the Hereditary Diffuse Gastric Cancer family:

diffuse gastric cancer

Diseases related to Diffuse Gastric Cancer via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 125)
idRelated DiseaseScoreTop Affiliating Genes
1hereditary diffuse gastric cancer31.8CDH1
2tubular adenocarcinoma30.7ERBB2, CDH1, CTNNB1, CTNNA1
3gastric cancer risk after h. pylori infection30.6IL1RN
4breast cancer30.5ERBB2, KRAS, CDH1, CTNNB1
5cleft lip30.4GSTM1, MTR
6bladder carcinoma30.4GSTP1, ERBB2, CDH3, CDH1, CTNNA1
7gastric cancer, somatic30.3KRAS, ERBB2
8basal cell carcinoma30.2XRCC3, GSTM1, GSTT1, ERCC2, ERCC1, CDH3
9pancreatitis30.1IL1B, GSTP1, KRAS
10adenoma29.9CTNNA1, CTNNB1, CDH1, CDH3, KRAS, ERCC1
11adenocarcinoma29.6CTNNA1, CTNNB1, CDH1, CDH3, KRAS, ERCC1
12mucinous adenocarcinoma10.7
13cardiac tamponade10.5
14bile duct signet ring cell carcinoma10.5
15pancreatic signet ring cell adenocarcinoma10.5
16duodenitis10.4
17signet ring cell adenocarcinoma10.4
18prostate signet ring cell adenocarcinoma10.4
19ampullary signet ring cell adenocarcinoma10.4
20small cell carcinoma10.4
21neuroendocrine carcinoma10.3
22thrombotic thrombocytopenic purpura10.3
23gastrointestinal stromal tumor10.3
24linitis plastica10.3
25large cell carcinoma10.3
26erysipelas10.3
27gallbladder signet ring cell adenocarcinoma10.3
28breast signet ring cell adenocarcinoma10.3
29pleomorphic carcinoma10.3
30dermatomyositis10.3
31elephantiasis10.3
32hemolytic anemia10.3
33lung squamous cell carcinoma10.3
34myositis10.3
35prostatitis10.3
36purpura10.3
37schistosomiasis10.3
38granulosa cell tumor of the ovary10.3
39retroperitoneal fibrosis10.3
40multiple endocrine neoplasia10.3
41gastric outlet obstruction10.3
42degenerative disc disease10.1IL1B
43dengue shock syndrome10.1IL1RN
44hailey-hailey disease10.1CDH3
45microinvasive gastric cancer10.1CTNNA1, CDH1
46chronic infantile neurological cutaneous articular syndrome10.1IL1B, IL1RN
47exanthem10.1IL1RN, KRAS
48inflammatory breast carcinoma10.1CDH1, ERBB2
49chorioamnionitis10.1IL1RN, IL1B
50bronchiolo-alveolar adenocarcinoma10.1KRAS, CDH1

Graphical network of the top 20 diseases related to Diffuse Gastric Cancer:



Diseases related to diffuse gastric cancer

Symptoms for Diffuse Gastric Cancer

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Drugs & Therapeutics for Diffuse Gastric Cancer

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Diffuse Gastric Cancer

Search NIH Clinical Center for Diffuse Gastric Cancer

Genetic Tests for Diffuse Gastric Cancer

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Anatomical Context for Diffuse Gastric Cancer

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33MalaCards
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MalaCards organs/tissues related to Diffuse Gastric Cancer:

33
Breast, Lung, Pancreas, Skin, Prostate, Testes

Animal Models for Diffuse Gastric Cancer or affiliated genes

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37MGI
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Publications for Diffuse Gastric Cancer

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52PubMed
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Articles related to Diffuse Gastric Cancer:

(show top 50)    (show all 103)
idTitleAuthorsYear
1
An I+-E-catenin (CTNNA1) mutation in hereditary diffuse gastric cancer. (23208944)
2013
2
Searching for E-cadherin gene mutations in early onset diffuse gastric cancer and hereditary diffuse gastric cancer in Korean patients. (23264079)
2013
3
Laparoscopic prophylactic total gastrectomy with linear stapler side-to-side esophagojejunal anastomosis for hereditary diffuse gastric cancer syndrome in 2 siblings. (23752020)
2013
4
A systematic review of the indications for genetic testing and prophylactic gastrectomy among patients with hereditary diffuse gastric cancer. (22160243)
2012
5
Hereditary diffuse gastric cancer: the always-forgotten Meckel's diverticulum. (22240148)
2012
6
Endoscopic surveillance of patients with hereditary diffuse gastric cancer: biopsy recommendations after topographic distribution of cancer foci in a series of 10 CDH1-mutated gastrectomies. (23073328)
2012
7
De novo CDH1 mutation in a family presenting with early-onset diffuse gastric cancer. (21696387)
2012
8
Pancreatic ductal adenocarcinoma in hereditary diffuse gastric cancer. A case report. (21992816)
2012
9
Diffuse gastric cancer with peritoneal carcinomatosis can mimic Crohn's disease. (23185152)
2012
10
CDH1-related hereditary diffuse gastric cancer syndrome: clinical variations and implications for counseling. (22020549)
2012
11
Loss of E-cadherin in mouse gastric epithelial cells induces signet ring-like cells, a possible precursor lesion of diffuse gastric cancer. (21276134)
2011
12
Germline mutations of the E-cadherin gene in families with inherited invasive lobular breast carcinoma but no diffuse gastric cancer. (21271559)
2011
13
Preventive and therapeutic implications of positive CDH1 testing in diffuse gastric cancer. (21761101)
2011
14
The identification and management of hereditary diffuse gastric cancer in a large Jordanian family. (21681551)
2011
15
Prophylactic total gastrectomy for hereditary diffuse gastric cancer. Review of the literature. (21872467)
2011
16
CDH1 gene mutations do not contribute in hereditary diffuse gastric cancer in Poland. (20842455)
2010
17
Prophylactic laparoscopic gastrectomy for hereditary diffuse gastric cancer: a case series in a single family. (21333186)
2010
18
A novel truncating mutation in the E-cadherin gene in the first Iranian family with hereditary diffuse gastric cancer. (20471195)
2010
19
Hereditary diffuse gastric cancer due to a previously undescribed CDH1 splice site mutation. (20624523)
2010
20
Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer. (19965908)
2010
21
Prophylactic total gastrectomy (PTG) for hereditary diffuse gastric cancer (HDGC): the Newfoundland experience with 23 patients. (19408054)
2009
22
Hereditary diffuse gastric cancer: a manifestation of lost cell polarity. (19432899)
2009
23
CDH1 testing: can it predict the prophylactic or therapeutic nature of total gastrectomy in hereditary diffuse gastric cancer? (19636637)
2009
24
Using fruitflies to help understand the molecular mechanisms of human hereditary diffuse gastric cancer. (19247957)
2009
25
Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression. (19269290)
2009
26
A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population. (18482459)
2008
27
Molecular pathology of familial gastric cancer, with an emphasis on hereditary diffuse gastric cancer. (17513507)
2008
28
Hereditary diffuse gastric cancer and lost cell polarity: a short path to cancer. (18407736)
2008
29
Hereditary diffuse gastric cancer: surgery, surveillance and unanswered questions. (18684065)
2008
30
Endogastric capsule for E-cadherin gene (CDH1) promoter hypermethylation assessment in DNA from gastric juice of diffuse gastric cancer patients. (17986624)
2008
31
Histopathological and molecular analysis of gastrectomy specimens from hereditary diffuse gastric cancer patients has implications for endoscopic surveillance of individuals at risk. (18825658)
2008
32
Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer. (17363565)
2007
33
E-cadherin and hereditary diffuse gastric cancer. (17981184)
2007
34
CDH1 truncating mutations in the E-cadherin gene: an indication for total gastrectomy to treat hereditary diffuse gastric cancer. (17522512)
2007
35
Prophylactic laparoscopic-assisted total gastrectomy for hereditary diffuse gastric cancer. (17651578)
2007
36
E-cadherin missense mutations, associated with hereditary diffuse gastric cancer (HDGC) syndrome, display distinct invasive behaviors and genetic interactions with the Wnt and Notch pathways in Drosophila epithelia. (16600987)
2006
37
Cleft lip/palate and CDH1/E-cadherin mutations in families with hereditary diffuse gastric cancer. (15831593)
2006
38
A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain. (16870389)
2006
39
Diffuse gastric cancer. (16770139)
2006
40
Genetic aetiology of diffuse gastric cancer: so near, yet so far. (15235018)
2004
41
Prognostic analysis of E-cadherin gene promoter hypermethylation in patients with surgically resected, node-positive, diffuse gastric cancer. (15102685)
2004
42
Germline mutational analysis of CDH1 and pathologic features in familial cancer syndrome with diffuse gastric cancer/breast cancer proband in a Chinese family. (15135482)
2004
43
The unsolved enigma of CDH1 down-regulation in hereditary diffuse gastric cancer. (15313375)
2004
44
Screening E-cadherin germline mutations in Italian patients with familial diffuse gastric cancer: an analysis in the District of Urbino, Region Marche, Central Italy. (12908778)
2003
45
Genetic screening for hereditary diffuse gastric cancer. (12647996)
2003
46
E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer. (12216071)
2002
47
Hereditary diffuse gastric cancer: more answers or more questions? (11875020)
2002
48
Novel germline CDH1 mutations in hereditary diffuse gastric cancer families. (11968084)
2002
49
Hereditary diffuse gastric cancer. (11665720)
2001
50
Hereditary Diffuse Gastric Cancer (20301318)
1993

Variations for Diffuse Gastric Cancer

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Expression for genes affiliated with Diffuse Gastric Cancer

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Diffuse Gastric Cancer

Search GEO for disease gene expression data for Diffuse Gastric Cancer.

Pathways for genes affiliated with Diffuse Gastric Cancer

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50PathCards, 38NCBI BioSystems Database, 55Reactome, 30KEGG, 60Thomson Reuters, 51PharmGKB, 53QIAGEN, 57SinoBiological, 5Cell Signaling Technology, 61Tocris Bioscience
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Pathways related to Diffuse Gastric Cancer according to GeneCards/GeneDecks:

(show all 40)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.0CDH1, CTNNA1
2
Show member pathways
9.7KRAS, IL1B, IL1RN
3
Show member pathways
Prolactin Signaling Pathway38
Development Prolactin receptor signaling60
Leptin signaling pathway38
9.7ERBB2, KRAS, IL1RN
4
Show member pathways
9.5GSTP1, ERCC1
59.4GSTP1, GSTT1
69.2CDH1, CDH3, CTNNB1
79.2CTNNB1, CTNNA1, CDH1
89.2CTNNB1, CDH1, CTNNA1
99.2CDH1, CTNNB1, CTNNA1
109.2CTNNA1, CTNNB1, CDH1
119.2CTNNA1, CDH1, CTNNB1
129.2CTNNA1, CDH1, CTNNB1
139.2CDH1, CTNNB1, CTNNA1
14
Show member pathways
RAC1 signaling pathway38
9.2CTNNA1, CTNNB1, CDH1
159.2CTNNA1, CTNNB1, CDH1
169.2KRAS, CTNNB1, CDH1
179.2CTNNB1, KRAS, CTNNA1
18
Show member pathways
Development ERBB family signaling60
Development GDNF family signaling60
9.2CTNNB1, CDH1, ERBB2
199.2CDH1, CTNNB1, ERBB2
209.1IL1B, IL1RN, CTNNB1
219.0CTNNB1, CTNNA1, CDH1, CDH3
229.0CTNNB1, CDH3, CTNNA1, CDH1
239.0CDH1, CTNNB1, CTNNA1, CDH3
249.0CDH1, CDH3, CTNNA1, CTNNB1
25
Show member pathways
9.0CDH1, CTNNB1, CTNNA1, CDH3
26
Show member pathways
8.9CTNNB1, CDH1, CDH3, ERBB2
278.9ERBB2, CDH1, CTNNB1, CTNNA1
28
Show member pathways
8.9GSTT1, GSTP1, GSTM1
29
Show member pathways
glutathione-mediated detoxification I38
glutathione redox reactions I38
glutathione redox reactions II38
4-hydroxy-2-nonenal detoxification38
Glutathione metabolism60
Glutathione metabolism38
8.9GSTT1, GSTP1, GSTM1
308.9GSTM1, GSTP1, GSTT1
318.9GSTP1, GSTM1, GSTT1
328.9CTNNB1, CDH1, KRAS, XRCC3
33
Show member pathways
8.9ERBB2, CTNNB1, CTNNA1, KRAS
34
Show member pathways
8.8KRAS, CTNNB1, IL1B, ERBB2
35
Show member pathways
Signal transduction PTEN pathway60
8.7KRAS, CTNNB1, ERBB2, CDH1, CTNNA1
36
Show member pathways
8.5MTR, GSTT1, GSTM1, GSTP1
37
Show member pathways
Signaling Pathways in Glioblastoma38
8.3ERBB2, GSTP1, KRAS, CTNNB1, CDH1
38
Show member pathways
8.1CTNNA1, CTNNB1, CDH1, ERBB2, CCL8, IL1B
398.1KRAS, ERBB2, GSTP1, CDH1, CTNNB1, CTNNA1
40
Show member pathways
7.9CTNNA1, CCL8, IL1B, ERBB2, CDH3, CTNNB1

Compounds for genes affiliated with Diffuse Gastric Cancer

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45Novoseek, 51PharmGKB, 11DrugBank, 61Tocris Bioscience, 29IUPHAR, 24HMDB
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Compounds related to Diffuse Gastric Cancer according to GeneCards/GeneDecks:

(show top 50)    (show all 169)
idCompoundScoreTop Affiliating Genes
1vinylchloride459.6GSTM1, GSTT1, KRAS
2chi 2459.5GSTM1, GSTT1, CDH1, IL1RN
3platinum compounds519.4ERCC1, ERCC2, GSTP1
4leucovorin45 51 1111.4XRCC3, ERBB2, KRAS, ERCC1, ERCC2
5methylchloride459.3GSTM1, GSTT1, GSTP1
6s-phenylmercapturic acid459.3GSTM1, GSTT1, GSTP1
7cumene hydroperoxide459.2GSTT1, GSTM1, GSTP1
81,3-butadiene459.2GSTT1, GSTP1, GSTM1
9fluorouracil51 1110.2ERCC1, GSTP1, XRCC3, ERCC2
10p003459.2XRCC3, GSTM1, IL1RN, GSTT1, CDH1
11bcnu459.2ERCC1, GSTT1, ERCC2, GSTP1
12cetuximab45 51 1111.1CTNNB1, KRAS, ERBB2, ERCC1
13melphalan45 51 1111.1GSTP1, ERCC2, XRCC3, ERCC1
14platinum45 5110.1GSTP1, GSTT1, ERCC2, ERCC1
151-hydroxypyrene459.1GSTM1, GSTT1, GSTP1
16styrene459.1GSTP1, GSTT1, GSTM1
17celecoxib45 61 29 51 24 1114.0ERBB2, CDH1, IL1B, CTNNB1
18trichloroethylene459.0GSTT1, GSTP1, GSTM1
19hydrocarbons458.9GSTM1, ERCC2, GSTT1, GSTP1
201-chloro-24-dinitrobenzene458.9GSTM1, GSTT1, GSTP1
21ifosfamide45 119.9GSTT1, GSTP1, ERCC1, GSTM1
22gefitinib45 51 1110.9CTNNB1, CDH1, KRAS, ERBB2
23manganese superoxide458.9GSTM1, IL1RN, GSTP1, GSTT1
24benzo(a)pyrene458.9GSTM1, ERCC1, GSTP1, GSTT1
25docetaxel45 51 61 1111.8XRCC3, ERCC2, ERCC1, CDH1, ERBB2, GSTP1
26carboplatin45 51 1110.7GSTM1, GSTT1, ERBB2, ERCC1, GSTP1
27irinotecan45 51 1110.6ERCC1, XRCC3, KRAS, CDH1, ERBB2, GSTP1
28vincristine45 51 1110.6ERCC2, GSTM1, GSTP1, ERCC1, MTR
29curcumin458.6ERBB2, CTNNB1, CDH1, GSTP1, IL1B
30etoposide45 51 61 1111.5ERCC1, CDH1, ERBB2, GSTT1, GSTP1
31vitamin d458.5KRAS, ERBB2, CDH1, CTNNB1, GSTM1, IL1RN
32paraffin458.5KRAS, GSTP1, ERBB2, CDH3, CTNNB1, CTNNA1
33aspirin45 51 29 2411.4CDH1, ERBB2, CTNNB1, IL1B, IL1RN, GSTP1
34n acetylcysteine458.3XRCC3, CTNNB1, CDH1, IL1B, GSTP1, ERBB2
35valine458.3GSTT1, GSTP1, GSTM1, ERBB2, MTR, KRAS
36phosphotyrosine458.3CTNNA1, CDH1, HNRNPU, ERBB2, CTNNB1
37oxaliplatin45 51 1110.2GSTT1, GSTP1, GSTM1, KRAS, ERCC1, ERCC2
38p002458.2KRAS, ERBB2, CTNNB1, IL1RN, GSTM1, GSTT1
39thymidylate458.2ERBB2, GSTP1, GSTM1, MTR, CDH1, ERCC1
40creatinine458.1GSTT1, GSTP1, GSTM1, MTR, IL1RN, ERCC1
41cyclophosphamide45 51 119.9GSTM1, GSTP1, ERBB2, ERCC2, ERCC1, MTR
42paclitaxel45 51 119.8GSTP1, ERBB2, ERCC1, KRAS, CDH1, CTNNA1
43folate457.8CDH1, GSTT1, MTR, ERBB2, ERCC2, GSTP1
44methotrexate51 45 119.7GSTP1, ERBB2, MTR, IL1RN, CDH1, ERCC1
455fluorouracil457.5ERBB2, GSTP1, ERCC2, ERCC1, KRAS, CDH1
46tyrosine457.4CTNNA1, HNRNPU, CCL8, IL1RN, ERBB2, ERCC1
47vegf457.3CTNNA1, GSTP1, CTNNB1, IL1RN, IL1B, ERBB2
48doxorubicin45 51 119.2ERCC1, GSTT1, GSTP1, CTNNB1, CDH1, ERBB2
49estrogen456.6IL1RN, GSTT1, KRAS, CDH1, CTNNB1, CDH3
50cisplatin45 51 61 119.4ERCC1, ERCC2, ERBB2, XRCC3, GSTM1, MTR

GO Terms for genes affiliated with Diffuse Gastric Cancer

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16Gene Ontology
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Cellular components related to Diffuse Gastric Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1zonula adherensGO:0059159.5CTNNB1, CTNNA1
2catenin complexGO:0163429.4CTNNA1, CTNNB1, CDH1
3cell-cell adherens junctionGO:0059139.4CDH3, CDH1, CTNNB1
4basolateral plasma membraneGO:0163239.1ERBB2, CDH1, CTNNB1
5perinuclear region of cytoplasmGO:0484718.9CTNNB1, CDH1, ERBB2, XRCC3
6plasma membraneGO:0058867.6IL1RN, GSTP1, ERBB2, KRAS, CDH3, CDH1
7cytosolGO:0058296.8MTR, IL1B, GSTM1, GSTP1, GSTT1, CTNNB1
8cytoplasmGO:0057376.7XRCC3, IL1RN, GSTM1, GSTP1, ERBB2, ERCC2

Biological processes related to Diffuse Gastric Cancer according to GeneCards/GeneDecks:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1fever generationGO:00166010.2IL1B, IL1RN
2adherens junction organizationGO:03433210.1CTNNA1, CDH1, CDH3
3cell-cell junction organizationGO:04521610.0CDH3, CDH1, CTNNA1
4cell junction assemblyGO:03432910.0CTNNA1, CDH1, CDH3
5UV protectionGO:0096509.9ERCC1, ERCC2
6positive regulation of protein phosphorylationGO:0019349.8IL1B, ERBB2, KRAS
7nucleotide-excision repair, DNA damage removalGO:0007189.8ERCC1, ERCC2
8regulation of protein localization to cell surfaceGO:20000089.7CTNNB1, CDH1
9regulation of ERK1 and ERK2 cascadeGO:0703729.6GSTP1, ERBB2
10cellular response to indole-3-methanolGO:0716819.5CTNNA1, CTNNB1, CDH1
11hair cell differentiationGO:0353159.5CTNNB1, ERCC2
12positive regulation of muscle cell differentiationGO:0511499.4CTNNA1, CTNNB1
13glutathione derivative biosynthetic processGO:19016879.2GSTT1, GSTP1, GSTM1
14glutathione metabolic processGO:0067499.2GSTM1, GSTP1, GSTT1
15regulation of angiogenesisGO:0457659.1CTNNB1, ERBB2
16response to drugGO:0424938.9IL1RN, GSTT1, CDH3, CDH1, CTNNB1
17xenobiotic metabolic processGO:0068058.8MTR, GSTM1, GSTP1, GSTT1
18positive regulation of transcription, DNA-templatedGO:0458938.7IL1B, ERCC2, CDH1, CTNNB1

Molecular functions related to Diffuse Gastric Cancer according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1gamma-catenin bindingGO:04529510.1CTNNA1, CDH1
2interleukin-1 receptor bindingGO:00514910.0IL1B, IL1RN
3cadherin bindingGO:0452969.4CTNNA1, CTNNB1
4protein domain specific bindingGO:0199049.4IL1B, ERCC1, CDH1
5protein phosphatase bindingGO:0199039.3ERBB2, CDH1, CTNNB1
6glutathione transferase activityGO:0043649.1GSTT1, GSTP1, GSTM1
7protein C-terminus bindingGO:0080228.9CTNNB1, ERCC1, ERCC2, ERBB2
8protein bindingGO:0055156.6ERBB2, GSTP1, HNRNPU, XRCC3, ERCC2, ERCC1

Products for genes affiliated with Diffuse Gastric Cancer

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Sources for Diffuse Gastric Cancer

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet