Dihydroxyadeninuria disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Aliases & Classifications for Dihydroxyadeninuria

Sources:
⁴⁸NIH Rare Diseases, ⁶⁸UMLS
See all MalaCards sources

Aliases & Descriptions for Dihydroxyadeninuria:

Name: Dihydroxyadeninuria ⁴⁸

Adenine Phosphoribosyltransferase Deficiency ⁶⁸

Aprt Deficiency ⁴⁸

Classifications:

MalaCards categories:
Global: Rare diseases

See all MalaCards categories (disease lists)

Summaries for Dihydroxyadeninuria

Sources:
³⁶MalaCards
See all MalaCards sources

MalaCards based summary: Dihydroxyadeninuria, also known as adenine phosphoribosyltransferase deficiency, is related to adenine phosphoribosyltransferase deficiency and lesch-nyhan syndrome. An important gene associated with Dihydroxyadeninuria is APRT (Adenine Phosphoribosyltransferase).

Related Diseases for Dihydroxyadeninuria

Sources:
²⁰GeneAnalytics, ²¹GeneCards
See all MalaCards sources

Diseases related to Dihydroxyadeninuria via text searches within MalaCards or GeneCards Suite gene sharing:

id	Related Disease	Score
1	adenine phosphoribosyltransferase deficiency	11.9
2	lesch-nyhan syndrome	9.8
3	xanthinuria	9.8
4	primary hyperoxaluria	9.8
5	teratocarcinoma	9.8
6	hereditary xanthinuria	9.8

Graphical network of diseases related to Dihydroxyadeninuria:

Symptoms & Phenotypes for Dihydroxyadeninuria

Drugs & Therapeutics for Dihydroxyadeninuria

Sources:
¹BitterDB, ⁴ClinicalTrials, ¹⁰DGIdb, ¹⁴DrugBank, ²⁹HMDB, ³³IUPHAR, ⁵⁰Novoseek, ⁵⁶PharmGKB
See all MalaCards sources

Drugs for Dihydroxyadeninuria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)

id

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Allopurinol

approved

Phase 4

145

315-30-0

2094

Synonyms:

1,5-Dihydro-4H-pyrazolo(3,4-D)pyrimidin-4-one

1,5-Dihydro-4H-pyrazolo(3,4-D)pyrimidine-4-one

184856-42-6

1H-Pyrazolo(3,4-D)pyrimidin-4-ol

22767-92-6

315-30-0

39464-14-7

4'-Hydroxypyrazolol(3,4-D)pyrimidine

4-HPP

4-Hydroxy-1H-pyrazolo(3,4-D)pyrimidine

4-Hydroxy-3,4-pyrazolopyrimidine

4-Hydroxypyrazolo(3,4-D)pyrimidine

4-Hydroxypyrazolopyrimidine

4-Hydroxypyrazolyl(3,4-D)pyrimidine

4H-Pyrazolo(3,4-D)pyrimidin-4-one

7HP

A 8003

A0907

A8003_SIGMA

AC-019

AC1L1CWL

AC1Q6FWV

AC1Q6GP7

AKOS000267490

AKOS000269759

AL-100

Adenock

Ailural

Ailurial

Allo-Puren

Allohexal

Allohexan

Alloprin

Allopur

Allopurin

Allopurinol

Allopurinol Sodium

Allopurinol(I)

Allopurinolum

Allopurinolum [INN-Latin]

Allorin

Allozym

Allpargin

Allural

Aloprim

Alopurinol

Alopurinol [INN-Spanish]

Aloral

Alositol

Aluline

Anoprolin

Anzief

Apo-Allopurinol

Apulonga

Apurin

Apurol

Atisuril

B. W. 56-158

BB_SC-5394

BIM-0061756.0001

BSPBio_001798

BW 56-158

BW 56158

BW-56-158

Bio-0799

Bleminol

Bloxanth

C5H4N4O

CCRIS 626

CHEBI:40279

CHEBI:495607

CHEMBL1467

CID2094

CPD-9024

CPD000059083

Caplenal

Capurate

Cellidrin

Cosuric

D000493

DB00437

Dabrosin

Dabroson

DivK1c_000685

Dura Al

EINECS 206-250-9

EN000932

EU-0100102

Embarin

Epidropal

Epuric

Foligan

Geapur

Gichtex

Gotax

HMS1920A15

HMS2091G15

HMS502C07

HPP

HSDB 3004

Hamarin

Hexanuret

I03-0052

IDI1_000685

Jenapurinol

Jsp005881

KBio1_000685

KBio2_000386

KBio2_002954

KBio2_005522

KBio3_001298

KBioGR_000550

KBioSS_000386

Ketanrift

Ketobun-A

LS-1180

Ledopur

Lopac-A-8003

Lopac0_000102

Lopurin

Lysuron

MLS000069453

MLS001148183

Milurit

Milurite

Miniplanor

MolPort-000-141-383

MolPort-000-870-337

MolPort-004-758-159

MolPort-004-758-166

MolPort-004-758-167

MolPort-004-758-643

Monarch

NCGC00015094-01

NCGC00015094-03

NCGC00015094-06

NCGC00091134-01

NCGC00091134-02

NCGC00091134-03

NCGC00094580-01

NCGC00094580-02

NCIOpen2_001825

NINDS_000685

NSC 101655

NSC 1390

NSC-1390

NSC101655

NSC1390

Nektrohan

Novopurol

Pan Quimica

Prestwick_511

Progout

Pureduct

Purinol

Quimica, Pan

Remid

Riball

Rimapurinol

Roucol

S1630_Selleck

SAM002554884

SMR000059083

SPBio_000056

SPECTRUM1500108

STK378584

STK711106

Sigapurol

Spectrum2_000098

Spectrum3_000289

Spectrum4_000135

Spectrum5_000768

Spectrum_000026

Suspendol

Takanarumin

Tipuric

UNII-63CZ7GJN5I

Urbol

Uribenz

Uricemil

Uridocid

Uriprim

Uripurinol

Uritas

Urobenyl

Urolit

Urosin

Urtias

Urtias 100

Xanthomax

Xanturat

Xanturic

Zygout

Zyloprim

Zyloprim (tn)

Zyloric

allopurinol

nchembio.92-comp3

nchembio732-comp4

2

Febuxostat

approved

Phase 4

55

144060-53-7

134018

Synonyms:

111GE013

144060-53-7

2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE-CARBOXYLIC ACID

2-(3-Cyano-4-(2-methylpropoxy)phenyl)-4-methylthiazole-5-carboxylic acid

2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylic acid

2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid

2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid

AC-425

AC1L33UC

Adenuric

C16H16N2O3S

CHEBI:45943

CHEBI:747206

CHEMBL1164729

CID134018

D01206

DB03786

FT-0081351

Febuxostat

Febuxostat (JAN/USAN/INN)

Febuxostat [USAN]

Febuxostatum

Fébuxostat

LS-173202

MolPort-005-940-740

S1547

S1547_Selleck

TEI

TMX 67

TMX-67

TMX-67, Adenuric, Uloric, Febuxostat

Tei 6720

Tei-6720

UNII-101V0R1N2E

Uloric

3

Protective Agents

Phase 4

7443

4

Antirheumatic Agents

Phase 4

10956

5

Antioxidants

Phase 4

3050

6

Antimetabolites

Phase 4

12054

7

Noni

Nutraceutical

9

Interventional clinical trials:

id	Name	Status	NCT ID	Phase
1	Effect of Allopurinol and Febuxostat on Urinary 2,8-Dihydroxyadenine Excretion	Completed	NCT02752633	Phase 4
2	Rare Kidney Stone Consortium Patient Registry	Recruiting	NCT00588562
3	Rare Kidney Stone Consortium Biobank	Recruiting	NCT02026388
4	Health-related Quality of Life in Rare Kidney Stone	Recruiting	NCT02124395
5	Prospective Research Rare Kidney Stones (ProRKS)	Recruiting	NCT02780297