DCM
MCID: DLT002
MIFTS: 76

Dilated Cardiomyopathy (DCM) malady

Categories: Genetic diseases, Rare diseases, Cardiovascular diseases, Neuronal diseases, Ear diseases

Aliases & Classifications for Dilated Cardiomyopathy

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Aliases & Descriptions for Dilated Cardiomyopathy:

Name: Dilated Cardiomyopathy 35 11 23 48 24 27 50 13
Familial Dilated Cardiomyopathy 11 48 25 68
Idiopathic Dilation Cardiomyopathy 11 68
Dilated Cardiomyopathy, Familial 48 27
Primary Dilated Cardiomyopathy 11 27
Congestive Cardiomyopathy 11 25
Cardiomyopathy, Dilated 39 68
Dcm 48 43
 
Hypokinetic Dilated Cardiomyopathy, Familial 48
Primary Familial Dilated Cardiomyopathy 25
Cardiomyopathy, Familial Idiopathic 68
Familial Idiopathic Cardiomyopathy 25
Idiopathic Dilated Cardiomyopathy 48
Cardiomyopathy, Familial Dilated 48
Fdc 25

Classifications:



External Ids:

Disease Ontology11 DOID:12930
ICD1030 I42.0
MeSH39 D002311
NCIt45 C84673

Summaries for Dilated Cardiomyopathy

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NIH Rare Diseases:48 Dilated cardiomyopathy (dcm) is a disease of the heart muscle which primarily affects the heart's main pumping chamber, the left ventricle. it is the most common type of cardiomyopathy and typically affects those aged 20 to 60. the left ventricle of affected individuals becomes enlarged (dilated) and cannot pump blood to the body with as much force as a healthy heart can. the heart muscle also has difficulty contracting normally, which can lead to irregular heartbeats (arrhythmia), blood clots, or sudden death. over time, the heart becomes weaker and heart failure can occur. while the cause of dilated cardiomyopathy is often unknown (idiopathic), some cases are acquired and roughly half are inherited or familial. also, dcm can be a feature of many genetic syndromes. familial dilated cardiomyopathy is most often inherited in an autosomal dominant pattern. familial dilated cardiomyopathy is caused by mutations in several different genes, most commonly in the ttn gene (found in about 20% of cases). dcm treatment may include medication, pacemakers, implantable cardiac defibrillators, or heart transplantation.  last updated: 1/2/2017

MalaCards based summary: Dilated Cardiomyopathy, also known as familial dilated cardiomyopathy, is related to cardiomyopathy, dilated, 1hh and familial partial lipodystrophy. An important gene associated with Dilated Cardiomyopathy is LMNA (Lamin A/C), and among its related pathways are Dilated cardiomyopathy and Cardiac conduction. The drugs inamrinone lactate and inamrinone have been mentioned in the context of this disorder. Affiliated tissues include heart, bone and lung, and related mouse phenotypes are cardiovascular system and growth/size/body region.

Genetics Home Reference:25 Familial dilated cardiomyopathy is a genetic form of heart disease. It occurs when heart (cardiac) muscle becomes thin and weakened in at least one chamber of the heart, causing the open area of the chamber to become enlarged (dilated). As a result, the heart is unable to pump blood as efficiently as usual. To compensate, the heart attempts to increase the amount of blood being pumped through the heart, leading to further thinning and weakening of the cardiac muscle. Over time, this condition results in heart failure.

Disease Ontology:11 An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.

Wikipedia:71 Dilated cardiomyopathy (DCM) is a condition in which the heart becomes enlarged and cannot pump blood... more...

GeneReviews for NBK1309

Related Diseases for Dilated Cardiomyopathy

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Diseases in the Cardiomyopathy family:

Cardiomyopathy, Dilated, 1cc Cardiomyopathy, Dilated, 1a
Cardiomyopathy, Dilated, 1v Cardiomyopathy, Dilated, 1d
Cardiomyopathy, Dilated, 1h Cardiomyopathy, Dilated, 1g
Cardiomyopathy, Dilated, 1i Cardiomyopathy, Dilated, 1nn
Cardiomyopathy, Dilated, 1z Cardiomyopathy, Dilated, 1e
Cardiomyopathy, Dilated, 1gg Cardiomyopathy, Dilated, 1l
Cardiomyopathy, Dilated, 1k Cardiomyopathy, Dilated, 1jj
Cardiomyopathy, Dilated, 1p Cardiomyopathy, Dilated, 1j
Cardiomyopathy, Dilated, 2b Cardiomyopathy, Dilated, 1q
Cardiomyopathy, Dilated, 1x Cardiomyopathy, Dilated, 1kk
Cardiomyopathy, Dilated, 1w Cardiomyopathy, Dilated, 1dd
Cardiomyopathy, Dilated, 1hh Cardiomyopathy, Dilated, 1m
Cardiomyopathy, Dilated, 1ii Cardiomyopathy, Dilated, 1o
Cardiomyopathy, Dilated, 1t Cardiomyopathy, Dilated, 1ee
Cardiomyopathy, Dilated, 1u Cardiomyopathy, Dilated, 1r
Cardiomyopathy, Dilated, 1bb Cardiomyopathy, Dilated, 2a
Cardiomyopathy, Dilated, 1ff Cardiomyopathy, Dilated, 3b
dilated cardiomyopathy Dmd-Related Dilated Cardiomyopathy
Dilated Cardiomyopathy 1c Dilated Cardiomyopathy 1aa
Dilated Cardiomyopathy 1b Lmna-Related Dilated Cardiomyopathy
Cardiomyopathy Due to Anthracyclines Mypn-Related Cardiomyopathy
Abcc9-Related Dilated Cardiomyopathy Actc1-Related Dilated Cardiomyopathy
Actn2-Related Dilated Cardiomyopathy Ankrd1-Related Dilated Cardiomyopathy
Bag3-Related Dilated Cardiomyopathy Cryab-Related Dilated Cardiomyopathy
Csrp3-Related Dilated Cardiomyopathy Des-Related Dilated Cardiomyopathy
Dsg2-Related Dilated Cardiomyopathy Eya4-Related Dilated Cardiomyopathy
Fktn-Related Dilated Cardiomyopathy Gatad1-Related Dilated Cardiomyopathy
Lama4-Related Dilated Cardiomyopathy Ldb3-Related Dilated Cardiomyopathy
Mybpc3-Related Dilated Cardiomyopathy Myh6-Related Dilated Cardiomyopathy
Myh7-Related Dilated Cardiomyopathy Nexn-Related Dilated Cardiomyopathy
Pln-Related Dilated Cardiomyopathy Prdm16-Related Dilated Cardiomyopathy
Psen1-Related Dilated Cardiomyopathy Psen2-Related Dilated Cardiomyopathy
Rbm20-Related Dilated Cardiomyopathy Scn5a-Related Dilated Cardiomyopathy
Sdha-Related Dilated Cardiomyopathy Sgcd-Related Dilated Cardiomyopathy
Taz-Related Dilated Cardiomyopathy Tcap-Related Dilated Cardiomyopathy
Tmpo-Related Dilated Cardiomyopathy Tnnc1-Related Dilated Cardiomyopathy
Tnni3-Related Dilated Cardiomyopathy Tnnt2-Related Dilated Cardiomyopathy
Tpm1-Related Dilated Cardiomyopathy Ttn-Related Dilated Cardiomyopathy
Vcl-Related Dilated Cardiomyopathy

Diseases related to Dilated Cardiomyopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 364)
idRelated DiseaseScoreTop Affiliating Genes
1cardiomyopathy, dilated, 1hh33.2RBM20, TNNT2
2familial partial lipodystrophy30.2DES, DMD, DSP, LDB3, LMNA, SCN5A
3dilated cardiomyopathy 1b12.2
4dilated cardiomyopathy 1c12.2
5dilated cardiomyopathy 1aa12.2
6cardiac conduction disease with or without dilated cardiomyopathy12.2
7dmd-related dilated cardiomyopathy12.1
8dilated cardiomyopathy with woolly hair, keratoderma, and tooth agenesis12.0
9lmna-related dilated cardiomyopathy12.0
10familial isolated dilated cardiomyopathy12.0
11dmd-associated dilated cardiomyopathy11.9
12cardiomyopathy, dilated, 3b11.9
13cardiomyopathy, dilated, 1e11.9
14malouf syndrome11.9
15abcc9-related dilated cardiomyopathy11.9
16eya4-related dilated cardiomyopathy11.9
17tcap-related dilated cardiomyopathy11.9
18actc1-related dilated cardiomyopathy11.8
19actn2-related dilated cardiomyopathy11.8
20ankrd1-related dilated cardiomyopathy11.8
21bag3-related dilated cardiomyopathy11.8
22csrp3-related dilated cardiomyopathy11.8
23des-related dilated cardiomyopathy11.8
24dsg2-related dilated cardiomyopathy11.8
25fktn-related dilated cardiomyopathy11.8
26ldb3-related dilated cardiomyopathy11.8
27left ventricular noncompaction 3, with or without dilated cardiomyopathy11.8
28myh6-related dilated cardiomyopathy11.8
29myh7-related dilated cardiomyopathy11.8
30nexn-related dilated cardiomyopathy11.8
31pln-related dilated cardiomyopathy11.8
32psen1-related dilated cardiomyopathy11.8
33psen2-related dilated cardiomyopathy11.8
34rbm20-related dilated cardiomyopathy11.8
35scn5a-associated dilated cardiomyopathy11.8
36scn5a-related dilated cardiomyopathy11.8
37sgcd-related dilated cardiomyopathy11.8
38taz-related dilated cardiomyopathy11.8
39tmpo-related dilated cardiomyopathy11.8
40tnnt2-related dilated cardiomyopathy11.8
41vcl-related dilated cardiomyopathy11.8
42dilated cardiomyopathy with quadriceps myopathy11.8
43cryab-related dilated cardiomyopathy11.8
44gatad1-related dilated cardiomyopathy11.8
45lama4-related dilated cardiomyopathy11.8
46mybpc3-related dilated cardiomyopathy11.8
47prdm16-related dilated cardiomyopathy11.8
48sdha-related dilated cardiomyopathy11.8
49tnnc1-related dilated cardiomyopathy11.8
50tnni3-related dilated cardiomyopathy11.8

Graphical network of the top 20 diseases related to Dilated Cardiomyopathy:



Diseases related to dilated cardiomyopathy

Symptoms & Phenotypes for Dilated Cardiomyopathy

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MGI Mouse Phenotypes related to Dilated Cardiomyopathy according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000538511.4ACTC1, BAG3, CSRP3, DES, DMD, DSP
2MP:000537811.4ACTC1, BAG3, CSRP3, DMD, DSP, LDB3
3MP:000537611.4ACTC1, BAG3, CSRP3, DES, DMD, LDB3
4MP:001076811.3ACTC1, BAG3, CSRP3, DES, DMD, DSP
5MP:000536910.6ACTC1, BAG3, CSRP3, DES, DMD, DSP

Drugs & Therapeutics for Dilated Cardiomyopathy

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Drugs for Dilated Cardiomyopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 167)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AmlodipineapprovedPhase 449688150-42-92162
Synonyms:
()-Amlodipine
(RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)
3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxy)methyl)-4-(2-chlorphenyl)-1,4-dihydro-6-methyl-3,5-pyridindicarboxylat
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(O-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (.+/-.)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
88150-42-9
88150-47-4 (maleate (1:1))
AC-4535
AC1L1D26
AC1Q32ZS
AMLODIPINE BASE
AMVAZ
Ambap88150-42-9
Amlocard
Amlodipine
Amlodipine (INN)
Amlodipine Benzenesulfonate
Amlodipine Besilate
Amlodipine Besylate
Amlodipine Free Base
Amlodipine [INN:BAN]
Amlodipine besilate
Amlodipine besylate
Amlodipine free base
Amlodipino
Amlodipino [Spanish]
Amlodipinum
Amlodipinum [Latin]
Amlodis
Amlopres
Amlor
 
Amvaz
BIDD:GT0810
BRD-A22032524-074-02-4
BRD-A22032524-074-03-2
BSPBio_002727
C06825
CHEBI:2668
CHEMBL1491
CID2162
CPD000469198
Coroval
D07450
DB00381
HMS2052N03
HMS2089H07
I14-0798
Intervask
Istin
KBio3_001947
KBioGR_001643
LS-131183
Lipinox
Lotrel
MLS001401409
MolPort-001-792-963
NCGC00165957-01
NCGC00165957-02
NCGC00165957-03
Norvasc
Norvasc (TN)
Pelmec
R,S)-Amlodipine
Racemic Amlodipine
SAM001246705
SMR000469198
SPBio_000351
Spectrum2_000486
Spectrum3_001004
Spectrum4_001132
Spectrum5_001550
UK-4834011
UNII-1J444QC288
amlodipine
2
Valsartanapproved, investigationalPhase 4295137862-53-460846
Synonyms:
(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
(S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(s)-2-(n-((2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl)pentanamido)-3-methylbutanoic acid
137862-53-4
AC-4543
AC1L1U1M
AC1Q5QIK
Ambap137862-53-4
Aventis brand of valsartan
BIDD:GT0345
BRD-K45158365-001-02-3
BSPBio_003501
Bio-0796
C081489
C24H29N5O3
CEPA brand of valsartan
CGP 48933
CGP-48933
CHEBI:9927
CHEMBL1069
CID60846
CPD000466318
D00400
DB00177
Diovan
Diovan (TN)
Diovan, Valsartan
Esteve brand of valsartan
HMS1922L21
HMS2051L12
HMS2093K22
HSDB 7519
KBio2_002287
KBio2_004855
KBio2_007423
KBio3_003006
KBioGR_001078
KBioSS_002289
 
Kalpress
L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)
LS-161334
Lacer brand of valsartan
MLS000759423
MLS001424088
Miten
MolPort-002-507-854
MolPort-003-666-608
N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-valeryl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)valine
Nisis
Nisis||
Novartis brand of valsartan
Provas
S1894_Selleck
SAM001246581
SMR000466318
SPBio_001260
SPECTRUM1505209
Sanol brand of valsartan
Schwarz brand of valsartan
Spectrum2_001120
Spectrum3_001831
Spectrum4_000749
Spectrum5_001582
Spectrum_001796
TL8000869
Tareg
UNII-80M03YXJ7I
Vals
Valsarran
Valsartan (JAN/USAN/INN)
Valsartan [USAN:INN]
valsartan
walsartan
|Tareg
3
Hydrochlorothiazideapproved, vet_approvedPhase 441358-93-53639
Synonyms:
125727-50-6
3,4-Dihydro-6-chloro-7-sulfamyl-1,2, 4-benzothi
3,4-Dihydrochlorothiazide
58-93-5
6-Chloro-7-sulfamoyl-3, 4-dihy
8049-49-8
AB00052012
AC-11072
AC1L1GDT
AC1Q55FM
AF-614/30832002
AKOS000121373
ARONIS24316
Acesistem
Acuilix
Acuretic
Aldactazide
Aldactazide 25/25
Aldazida
Aldectazide 50/50
Aldoril
Ambap58-93-5
Apo-Hydro
Apresazide
Aquarills
Aquarius
Aquazide H
Aquazide-H
BAS 00371709
BIDD:GT0153
BPBio1_000019
BRD-K13078532-001-05-2
BRN 0625101
BSPBio_000017
BSPBio_002132
Bio-0714
Bremil
Briazide
C7H8ClN3O4S2
CAS-58-93-5
CCRIS 2082
CHEMBL435
CID3639
CPD000035778
Caplaril
Capozide
Carozide
Catiazida
Chlorizide
Chlorosulthiadil
Chlorothiazide
Chlorsulfonamidodihydrobenzothiadiazine dioxide
Chlorzide
Chlothia
Cidrex
Clorana
Component of Butizide Prestabs
Concor Plus
Condiuren
D00340
D006852
DB00999
Diaqua
Dichlorosal
Dichlorotride
Dichlothiazide
Dichlotiazid
Dichlotride
Diclotride
Dicyclotride
Didral
Dihydran
Dihydrochlorothiazid
Dihydrochlorothiazide
Dihydrochlorothiazidum
Dihydrochlorurit
Dihydrochlorurite
Dihydroxychlorothiazidum
Direma
Disalunil
Disothiazid
Diu 25 Vigt
Diu-Melusin
Diu-melusin
Diuril
Diurogen
DivK1c_000289
Dixidrasi
Drenol
Dyazide
EINECS 200-403-3
EU-0100614
Esidrex
Esidrix
Esidrix (TN)
Esimil
Esoidrina
FT-0082750
Fluvin
H 4759
H1274
H2910_SIAL
H4759_SIAL
HCT
HCT-Isis
HCTZ
HCZ
HMS1568A19
HMS1920D19
HMS2091L05
HMS500O11
HMS553N04
HSDB 3096
Hidril
Hidro-Niagrin
Hidrochlortiazid
Hidroclorotiazida
Hidroclorotiazida [INN-Spanish]
Hidroronol
Hidrosaluretil
Hidrotiazida
Hyclosid
Hydrex-semi
Hydril
Hydro Par
Hydro-Aquil
Hydro-D
Hydro-Diuril
Hydro-Saluric
Hydro-T
Hydro-chlor
HydroDIURIL
Hydrochlorat
Hydrochloro Thiazide
Hydrochlorot
Hydrochlorothiazid
Hydrochlorothiazide
Hydrochlorothiazide (JP15/USP/INN)
Hydrochlorothiazide Intensol
Hydrochlorothiazide [INN:BAN:JAN]
 
Hydrochlorothiazidum
Hydrochlorothiazidum [INN-Latin]
Hydrochlorthiazide
Hydrochlorthiazidum
Hydrocot
Hydrodiuretic
Hydrodiuril
Hydropres
Hydrosaluric
Hydrothide
Hydrozide
Hydrozide Injection, Veterinary
Hypothiazid
Hypothiazide
Hytrid
Hyzaar
I09-0531
IDI1_000289
Idroclorotiazide
Idroclorotiazide [DCIT]
Idrotiazide
Inderide
Inderide 80/25
Indroclor
Ivaugan
Jen-Diril
KBio1_000289
KBio2_001357
KBio2_003925
KBio2_006493
KBio3_001352
KBioGR_000351
KBioSS_001357
LS-243
Lopac-H-4759
Lopac0_000614
Lopressor HCT
Lotensin HCT
Lotensin Hct
MLS000069619
Manuril
Maschitt
Maxzide
Maybridge Compound 10
Maybridge1_004336
Mazide 25 mg
Medozide
Megadiuril
Microzide
Microzide (TN)
Mictrin
Mikorten
Modurcen
Moduretic
MolPort-000-144-465
NCGC00015508-01
NCGC00015508-02
NCGC00015508-03
NCGC00015508-07
NCGC00015508-12
NCGC00021906-03
NCGC00021906-04
NCGC00021906-05
NCGC00021906-06
NCGC00021906-07
NCGC00021906-08
NCI-C55925
NCI60_004317
NINDS_000289
NSC 53477
NSC53477
Natrinax
Nefrix
Nefrol
Neo-Codema
Neo-Flumen
Neo-Minzil
Neo-codema
Neoflumen
Newtolide
Novodiurex
Oprea1_357174
Oretic
Pantemon
Panurin
Prestwick0_000009
Prestwick1_000009
Prestwick2_000009
Prestwick3_000009
Prestwick_263
Prinzide
Raunova Plus
Ro-Hydrazide
Ro-hydrazide
Roxane
S1708_Selleck
SAM002554901
SMR000035778
SPBio_001259
SPBio_001938
SPECTRUM1500335
STK315354
Saldiuril
Sectrazide
Selozide
Ser-Ap-Es
Servithiazid
Spectrum2_001040
Spectrum3_000456
Spectrum4_000006
Spectrum5_000824
Spectrum_000877
Spironazide
Su 5879
Tandiur
Thiaretic
Thiuretic
Thlaretic
Timolide
UNII-0J48LPH2TH
Unazid
Unipres
Urodiazin
Urozide
Vaseretic
Vetidrex
WLN: T66 BSWM EM DHJ HG ISZW
ZINC00896569
Ziac
Zide
adiazine-1,1-dioxide
component of Aldactazide
component of Aldoril
component of Caplaril
component of Cyclex
component of Dyazide
component of Esimil
diclot ride
dro-2H-1,2,4-benzothiadiazine 1,1-dioxide
hydrochlorothiazide
panurin dichloride
4
VerapamilapprovedPhase 413052-53-92520
Synonyms:
(+-)-Verapamil
(+/-)-VERAPAMIL
(1)-3-(3,4-Dimethoxyphenyl)-6-((5,6-dimethoxyphenethyl)methylamino)hexane-3-carbonitrile
2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-(1-methylethyl) pentanenitrile
2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile
5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile
5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile
52-53-9
56949-77-0
AB00053495
AC-16016
AC1L1DV5
Akilen
Anpec
Apo-Verap
Arpamyl
Arpamyl LP
BPBio1_000268
BRD-A09533288-001-02-7
BRD-A09533288-003-05-6
BSPBio_000242
BSPBio_001513
BSPBio_002358
Berkatens
Bio-0754
Bio1_000425
Bio1_000914
Bio1_001403
Bio2_000233
Bio2_000713
C07188
C27H38N2O4
CCRIS 6749
CHEBI:9948
CHEMBL6966
CID2520
CP-16533-1
CP-165331
Calan
Calan SR
Calan sr
Calaptin
Calaptin 240 SR
Calcan
Cardiabeltin
Cardiagutt
Cardibeltin
Cardioprotect
Caveril
Civicor
Civicor Retard
Coraver
Cordilox
Cordilox SR
Corpamil
Covera-HS
Covera-Hs
Covera-hs
D-365
D02356
DB00661
Dexverapamil
Dignover
Dilacoran
Dilacoran HTA
DivK1c_000399
Drosteakard
Durasoptin
EINECS 200-145-1
EINECS 260-462-6
Elthon
FT-0080127
Falicard
Finoptin
Flamon
Geangin
HMS1791L15
HMS1989L15
HMS2089H17
Harteze
Hexasoptin
Hexasoptin Retard
Hormitol
I06-0063
IDI1_000399
IDI1_033983
Ikacor
Ikapress
Inselon
Iproveratril
Isoptimo
Isoptin
Isoptin Retard
Isoptin SR
Isoptin sr
Isoptine
Isoptino
Isotopin
Izoptin
Jenapamil
KBio1_000399
KBio2_000233
KBio2_002343
KBio2_002801
KBio2_004911
KBio2_005369
KBio2_007479
KBio3_000465
KBio3_000466
 
KBio3_002823
KBioGR_000233
KBioGR_001372
KBioGR_002343
KBioSS_000233
KBioSS_002346
L001330
LS-174
Lekoptin
Lodixal
Lopac0_001237
Magotiron
Manidon
Manidon Retard
MolPort-000-721-258
NCGC00016083-14
NCGC00024710-04
NCGC00024710-05
NCGC00024710-06
NCGC00024710-07
NCGC00024710-08
NCGC00024710-09
NCI60_020143
NINDS_000399
NSC272366
NU-Verap
Novapamyl LP
Novo-Veramil
Nu-Verap
Ormil
Praecicor
Prestwick0_000141
Prestwick1_000141
Prestwick2_000141
Prestwick3_000141
Quasar
Rapam
Robatelan
SPBio_001820
SPBio_002181
STK538085
Securon
Spectrum2_001740
Spectrum4_000906
Spectrum5_001786
Tarka
UNII-CJ0O37KU29
Univer
Univex
VERAPAMIL
Vasolan
Vasomil
Vasopten
Vera-Sanorania
Verabeta
Veracaps SR
Veracim
Veracor
Verahexal
Veraloc
Veramex
Veramil
Verapamil
Verapamil (USAN/INN)
Verapamil AL
Verapamil Acis
Verapamil Atid
Verapamil Basics
Verapamil Ebewe
Verapamil HCl
Verapamil Henning
Verapamil Injection
Verapamil MSD
Verapamil NM
Verapamil NM Pharma
Verapamil Nordic
Verapamil PB
Verapamil Riker
Verapamil SR
Verapamil Verla
Verapamil [USAN:BAN:INN]
Verapamil [USAN:INN:BAN]
Verapamil [Usan:Ban:Inn]
Verapamil-AbZ
Verapamilo
Verapamilo [INN-Spanish]
Verapamilum
Verapamilum [INN-Latin]
Verapin
Verapress 240 SR
Veraptin
Verasal
Verasifar
Veratensin
Verdilac
Verelan
Verelan PM
Verelan SR
Verexamil
Veroptinstada
Verpamil
Vetrimil
Vortac
Vérapamil
alpha-((N-Methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile
alpha-(3-((2-(3,4-Dimethoxyphenyl)ethyl)-methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile
alpha-Isopropyl-alpha-((N-methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile
cMAP_000023
delta-365
nchembio.368-comp2
nchembio.79-comp5
5
Carvedilolapproved, investigationalPhase 4, Phase 216872956-09-32585
Synonyms:
(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
107741-96-8
72956-09-3
AB1004830
AC-1641
AC1L1E0B
Artist
Artist (TN)
Atlana Pharma brand of carvedilol
BM 14190
BM-14-190
BM-14.190
BM-14190
BRD-A10977446-001-04-8
BRD-A10977446-045-01-1
Bio-0014
C043211
C06875
C2260
C24H26N2O4
CHEBI:3441
CHEMBL723
CID2585
CPD000449280
Carvedilol
Carvedilol (JAN/USAN/INN)
Carvedilol [USAN:INN:BAN:JAN]
Carvedilolum
Carvedilolum [Latin]
Coreg
Coreg (TN)
Coreg CR
Coropres
Coropress
D00255
DB01136
DQ 2466
DQ-2466
Dibloc
 
Dilatrend
EG-P042
Eucardic
GlaxoSmithKline brand of carvedilol
HMS2051N03
HMS2089B09
HMS2093E12
HSDB 7044
I06-0064
I06-1477
KBio2_002145
KBio2_004713
KBio2_007281
KBio3_002323
KBioGR_001252
KBioSS_002145
Kredex
L001243
LS-121875
Lakeside brand of carvedilol
MLS000758299
MLS000759508
MLS001424092
MolPort-003-666-814
NCGC00167832-01
NCGC00167832-02
NCGC00167832-03
Querto
Roche brand of carvedilol
SAM001246736
SAM001247021
SK&F-105517
SKF 105517
SMR000449280
SPBio_001885
STK621453
Spectrum2_001673
Spectrum3_001182
Spectrum4_000636
Spectrum5_001436
Spectrum_001665
TL8005080
UNII-0K47UL67F2
carvedilol
carvedilol, (+-)-isomer
carvedilol, (R)-isomer
carvedilol, (S)-isomer
carvedilol, 14C-labeled
6
EnalaprilatapprovedPhase 4, Phase 3, Phase 212476420-72-96917719
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid dihydrate
1-((2S)-2-{[(1S)-1-CARBOXY-3-PHENYLPROPYL]AMINO}PROPANOYL)-L-PROLINE
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate
76420-72-9
AC1NUWEA
AC1OCEK7
BIDD:GT0752
C11720
C18H24N2O5.2H2O
CHEBI:116759
CHEBI:42302
CHEBI:4786
CHEBI:59877
CHEMBL1200697
CHEMBL577
CID5462501
CID6917719
CPD000466359
D03769
EAL
ENALAPRILAT INHIBITOR
Enalapril acid
Enalapril diacid
Enalaprilat
Enalaprilat (USP)
 
Enalaprilat anhydrous
Enalaprilate
Enalaprilatum
Enalaprilic acid
Enalprilate hydrate
HMS2051H16
HMS2089P04
LS-118903
LS-187219
MK-422
MLS000759476
MLS001424138
MolPort-005-943-792
N-[(1S)-1-Carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline--water (1/2)
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline—water (1/2)
NCGC00164593-01
S1657_Selleck
SAM001246684
SBB065733
SMR000466359
Vasotec I.V.
enalaprilat dihydrate
enalaprilat hydrate
enalprilat hydrate
enalprilate hydrate
7
Amiodaroneapproved, investigationalPhase 41221951-25-32157
Synonyms:
(2-Butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diidophenyl)methanone
(2-butyl-1-benzofuran-3-yl)(4-{[2-(diethylamino)ethyl]oxy}-3,5-diiodophenyl)methanone
(2-butyl-1-benzofuran-3-yl)-[4-(2-diethylaminoethyloxy)-3,5-diiodophenyl]methanone
(2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
(2-butylbenzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodo-phenyl]-methanone
(2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine
1951-25-3
2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran
2-Butyl-3-(3,5-diiodo-4-(beta-diethylaminoethoxy)benzoyl)benzofuran
2-Butyl-3-(4'-beta-N-diethylaminoethoxy-3',5'-diiodobenzoyl)benzofuran
2-Butyl-3-[3,5-diiodo-4-(2-di
2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone
2-Butyl-3-benzofuranyl p-((2-diethylamino)ethoxy)-m,m-diiodophenyl ketone
2-Butyl-3-benzofuranyl p-[(2-diethylamino)ethoxy]-m,m-diiodophenyl ketone
2-N-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
5-18-02-00353 (Beilstein Handbook Reference)
AB00053422
AC1L1D1R
AC1Q2VCU
ASTA Medica Brand of Amiodarone Hydrochloride
Alphapharm Brand of Amiodarone Hydrochloride
Amidorone
Aminodarone
Amio-Aqueous IV
Amiobeta
Amiodarex
Amiodarona
Amiodarona [INN-Spanish]
Amiodarone
Amiodarone (USAN/INN)
Amiodarone Base
Amiodarone HCL
Amiodarone Hydrochloride
Amiodarone [USAN:BAN:INN]
Amiodarons
Amiodaronum
Amiodaronum [INN-Latin]
Amiohexal
Amjodaronum
Ancar
Aratac
Armstrong Brand of Amiodarone Hydrochloride
Arycor
BIDD:GT0425
BIDD:PXR0146
BPBio1_000372
BRN 1271711
BSPBio_000338
BSPBio_001574
BSPBio_002580
Berenguer Infale Brand of Amiodarone Hydrochloride
Betapharm Brand of Amiodarone Hydrochloride
Bio1_000026
Bio1_000515
Bio1_001004
Bio2_000294
Bio2_000774
Braxan
C06823
C25H29I2NO3
CAS-19774-82-4
CBiol_001740
CHEBI:2663
CHEMBL633
CID2157
Corbionax
Cordarex
Cordarone
Cordarone Intravenous
D000638
D02910
DB01118
DivK1c_000079
EINECS 217-772-1
 
G Gam Brand of Amiodarone Hydrochloride
HMS1791O16
HMS1989O16
HMS2089C07
Hexal Brand of Amiodarone Hydrochloride
IDI1_000079
IDI1_034044
KBio1_000079
KBio2_000294
KBio2_000741
KBio2_002862
KBio2_003309
KBio2_005430
KBio2_005877
KBio3_000587
KBio3_000588
KBio3_001800
KBioGR_000294
KBioGR_001859
KBioSS_000294
KBioSS_000741
Ketone, 2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl
Ketone, 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl (7CI,8CI)
Kordaron
L 3428
L-3428
L001174
L3428
LS-87088
Labaz
Leurquin Brand of Amiodarone Hydrochloride
Lopac-A-8423
Lopac0_000122
MolPort-003-703-670
NCGC00015096-01
NCGC00015096-02
NCGC00015096-03
NCGC00015096-10
NCGC00024242-03
NCGC00024242-04
NCGC00024242-05
NCGC00024242-06
NCI60_041885
NINDS_000079
Ortacrone
Pacerone
Pharma Investi Brand of Amiodarone Hydrochloride
Prestwick0_000409
Prestwick1_000409
Prestwick2_000409
Prestwick3_000409
QTL1_000008
Rytmarone
SKF 33134-A
SKF 33134A
SPBio_001825
SPBio_002277
STK529812
STOCK1S-12240
Sanofi Winthrop Brand of Amiodarone Hydrochloride
Sedacoron
Sedacorone
Spectrum2_001813
Spectrum3_001050
Spectrum4_001190
Spectrum5_001533
Spectrum_000261
Tachydaron
UNII-N3RQ532IUT
UNM000001215003
Wyeth Brand of Amiodarone Hydrochloride
amiodarone
ethylaminoethoxy)benzoyl]benzofuran
nchembio.79-comp9
nchembio732-comp1
on
pms-Amiodarone
8
Benazeprilapproved, investigationalPhase 44586541-75-55362124
Synonyms:
2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid
86541-75-5
AC1NSFPL
BIDD:GT0800
BRD-K49807096-003-02-3
BSPBio_003487
Benazepril (INN)
Benazepril HCl
Benazepril Hydrochloride
Benazepril Sandoz
Benazepril Sandoz (TN)
Benazepril [INN:BAN]
Benazeprilum
Benazeprilum [Latin]
Briem
C06843
CGS-14824-A
CHEBI:3011
CHEMBL838
CID5362124
Cibacen
Cibacene
D07499
DB00542
 
Forteekor [veterinary]
Forteekor [veterinary] (TN)
KBio2_002457
KBio2_005025
KBio2_007593
KBio3_002707
KBioGR_000812
KBioSS_002464
LS-27973
Lotensin
NCGC00165740-01
NCGC00165740-02
SPBio_000343
STK627447
Spectrum2_000482
Spectrum3_001674
Spectrum4_000286
Spectrum5_001546
Spectrum_001922
UNII-UDM7Q7QWP8
[(3S)-3-({(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}amino)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
[(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
[(3S)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
benazapril
benazepril
benzazepril
9
Metoprololapproved, investigationalPhase 4, Phase 221237350-58-6, 51384-51-14171
Synonyms:
(+/-)-Metoprolol
(RS)-Metoprolol
1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol
1-(Isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanol
1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol
1-[(1-methylethyl)amino]-3-({4-[2-(methyloxy)ethyl]phenyl}oxy)propan-2-ol
1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
1-[4-(2-methoxyethyl)phenoxy]-3-propan-2-ylamino-propan-2-ol
3-[4-(2-methoxyethyl)phenoxy]-1-(propan-2-ylamino)propan-2-ol
37350-58-6
51384-51-1
54163-88-1
AB00053499
AC-19022
AC1L1HKM
AstraZeneca Brand of Metaoprolol Tartrate
AstraZeneca Brand of Seloken
BRD-A03623303-045-02-0
Beatrolol
Beloc
Beloc Duriles
Beloc-Duriles
BelocDuriles
Betaloc
Betaloc Astra
Betaloc-Astra
BetalocAstra
Betalok
C07202
CCRIS 4198
CGP 2175
CGP-2175
CGP2175
CHEBI:6904
CHEMBL13
CID4171
D008790
D02358
DB00264
DL-metoprolol
Dl-Metoprolol
Dutoprol
EINECS 253-483-7
EINECS 257-166-4
H 93 26
H 93-26
H 9326
 
HMS2090B15
HSDB 6531
I01-7125
I06-0125
Jsp006606
L000669
LOPRESSIDONE
LS-122450
Leiras Brand of Metoprolol Succinate or Metoprolol Tartrate
Lopresor
Lopresoretic
Lopressor
Lopressor HCT
Meijoprolol
Metohexal
Metoprolol
Metoprolol (USAN/INN)
Metoprolol Tartrate
Metoprolol [USAN:INN:BAN]
Metoprolol slow release
Metoprolol succinate
Metoprolol tartrate
Metoprololum
Metoprololum [INN-Latin]
Metroprolol
MolPort-005-938-039
NCGC00021148-02
NCGC00021148-03
NCGC00021148-04
Novartis Brand of Metprolol Tartrate
Preblok
Prelis
Presolol
Selo-Zok
Seloken
Seloken AstraZeneca Brand
Selopral
Seroken
Spesicor
Spesikor
TOPROL-XL
Tartrate, Metoprolol
Toprol
Toprol XL
Toprol-XL
UNII-GEB06NHM23
dl-Metoprolol
metoprolol
10
DoxazosinapprovedPhase 45874191-85-83157
Synonyms:
1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin
1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[4-(1,4-benzodioxan-2-yl)carpiperazin-1-yl)]-6,7-dimethoxyquinazoline mesylate
2-[4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-1-yl]-6,7-bis(methyloxy)quinazolin-4-amine
2-[4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
2-{4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine
74191-85-8
77883-43-3 (mesylate)
AC-11062
AC1L1FAT
AC1Q470P
AC1Q4EXN
AKOS001681453
BPBio1_000963
BRD-A13188892-066-03-3
BSPBio_000875
C06970
C23H25N5O5
CHEBI:4708
CHEMBL707
CID3157
CPD000097306
Cardura XL (TN)
Cardura-1
Cardura-2
Cardura-4
ChemDiv2_005017
D07874
D9815_SIGMA
DB00590
 
Doxazosin (INN)
Doxazosin [INN:BAN]
Doxazosin mesilate
Doxazosina
Doxazosina [Spanish]
Doxazosine
Doxazosine [French]
Doxazosinum
Doxazosinum [Latin]
HMS1383E01
HMS2090C20
I06-1346
IDI1_003732
L000738
LS-110228
Lopac0_000474
MolPort-001-684-491
NCGC00018158-06
NCGC00089775-02
Normothen
Oprea1_259518
Prestwick0_000858
Prestwick1_000858
Prestwick2_000858
Prestwick3_000858
SAM002589981
SPBio_002796
UK 33274
UK-33274
UNII-NW1291F1W8
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
doxazosin
11
Enalaprilapproved, vet_approvedPhase 4, Phase 3, Phase 212475847-73-35362032, 40466924
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline
(S)-1-{(S)-2-[1-((S)-ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester
75847-73-3
AC1NTUS5
Analapril
BIDD:GT0751
BPBio1_000340
BSPBio_000308
BSPBio_003035
Bonuten
C06977
CAS-76095-16-4
CHEBI:116847
CHEBI:4784
CHEMBL578
CID5388962
D07892
DivK1c_000408
Enalapril
Enalapril (INN)
Enalapril (TN)
Enalapril Bp
Enalapril Maleate
Enalapril Richet
Enalaprila
Enalaprila [INN-Spanish]
Enalaprilat
Enalaprilum
 
Enalaprilum [INN-Latin]
Gadopril
HMS2090E08
IDI1_000408
KBio1_000408
KBio2_001787
KBio2_004355
KBio2_006923
KBio3_002535
KBioGR_000355
KBioSS_001787
Kinfil
LS-190651
MolPort-002-885-877
N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline
N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl-L-proline
NCGC00016932-01
NCGC00021569-04
NCGC00021569-05
NCGC00021569-06
NINDS_000408
Prestwick3_000314
SPBio_001349
Spectrum2_001455
Spectrum3_001478
Spectrum4_000008
Spectrum5_001107
Spectrum_001307
Vaseretic
Vasotec
Vasotec IV
enalapril
12
AllopurinolapprovedPhase 4, Phase 1, Phase 2145315-30-02094
Synonyms:
1,5-Dihydro-4H-pyrazolo(3,4-D)pyrimidin-4-one
1,5-Dihydro-4H-pyrazolo(3,4-D)pyrimidine-4-one
184856-42-6
1H-Pyrazolo(3,4-D)pyrimidin-4-ol
22767-92-6
315-30-0
39464-14-7
4'-Hydroxypyrazolol(3,4-D)pyrimidine
4-HPP
4-Hydroxy-1H-pyrazolo(3,4-D)pyrimidine
4-Hydroxy-3,4-pyrazolopyrimidine
4-Hydroxypyrazolo(3,4-D)pyrimidine
4-Hydroxypyrazolopyrimidine
4-Hydroxypyrazolyl(3,4-D)pyrimidine
4H-Pyrazolo(3,4-D)pyrimidin-4-one
7HP
A 8003
A0907
A8003_SIGMA
AC-019
AC1L1CWL
AC1Q6FWV
AC1Q6GP7
AKOS000267490
AKOS000269759
AL-100
Adenock
Ailural
Ailurial
Allo-Puren
Allohexal
Allohexan
Alloprin
Allopur
Allopurin
Allopurinol
Allopurinol Sodium
Allopurinol(I)
Allopurinolum
Allopurinolum [INN-Latin]
Allorin
Allozym
Allpargin
Allural
Aloprim
Alopurinol
Alopurinol [INN-Spanish]
Aloral
Alositol
Aluline
Anoprolin
Anzief
Apo-Allopurinol
Apulonga
Apurin
Apurol
Atisuril
B. W. 56-158
BB_SC-5394
BIM-0061756.0001
BSPBio_001798
BW 56-158
BW 56158
BW-56-158
Bio-0799
Bleminol
Bloxanth
C5H4N4O
CCRIS 626
CHEBI:40279
CHEBI:495607
CHEMBL1467
CID2094
CPD-9024
CPD000059083
Caplenal
Capurate
Cellidrin
Cosuric
D000493
DB00437
Dabrosin
Dabroson
DivK1c_000685
Dura Al
EINECS 206-250-9
EN000932
EU-0100102
Embarin
Epidropal
Epuric
Foligan
Geapur
Gichtex
Gotax
HMS1920A15
HMS2091G15
HMS502C07
HPP
 
HSDB 3004
Hamarin
Hexanuret
I03-0052
IDI1_000685
Jenapurinol
Jsp005881
KBio1_000685
KBio2_000386
KBio2_002954
KBio2_005522
KBio3_001298
KBioGR_000550
KBioSS_000386
Ketanrift
Ketobun-A
LS-1180
Ledopur
Lopac-A-8003
Lopac0_000102
Lopurin
Lysuron
MLS000069453
MLS001148183
Milurit
Milurite
Miniplanor
MolPort-000-141-383
MolPort-000-870-337
MolPort-004-758-159
MolPort-004-758-166
MolPort-004-758-167
MolPort-004-758-643
Monarch
NCGC00015094-01
NCGC00015094-03
NCGC00015094-06
NCGC00091134-01
NCGC00091134-02
NCGC00091134-03
NCGC00094580-01
NCGC00094580-02
NCIOpen2_001825
NINDS_000685
NSC 101655
NSC 1390
NSC-1390
NSC101655
NSC1390
Nektrohan
Novopurol
Pan Quimica
Prestwick_511
Progout
Pureduct
Purinol
Quimica, Pan
Remid
Riball
Rimapurinol
Roucol
S1630_Selleck
SAM002554884
SMR000059083
SPBio_000056
SPECTRUM1500108
STK378584
STK711106
Sigapurol
Spectrum2_000098
Spectrum3_000289
Spectrum4_000135
Spectrum5_000768
Spectrum_000026
Suspendol
Takanarumin
Tipuric
UNII-63CZ7GJN5I
Urbol
Uribenz
Uricemil
Uridocid
Uriprim
Uripurinol
Uritas
Urobenyl
Urolit
Urosin
Urtias
Urtias 100
Xanthomax
Xanturat
Xanturic
Zygout
Zyloprim
Zyloprim (tn)
Zyloric
allopurinol
nchembio.92-comp3
nchembio732-comp4
13
SpironolactoneapprovedPhase 4, Phase 3, Phase 22321952-01-7, 52-01-75833
Synonyms:
4-18-00-01601 (Beilstein Handbook Reference)
4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate
496916-40-6
52-01-7
7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone
7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
AB00513806
AC-4214
AC1L1L8Q
Abbolactone
Acelat
Aldace
Aldactazide
Aldactide
Aldactone
Aldactone (TN)
Aldactone A
Alderon
Aldopur
Almatol
Alphapharm Brand of Spironolactone
Alpharma Brand of Spironolactone
Alter Brand of Spironolactone
Altex
Aquareduct
Ashbourne Brand of Spironolactone
Azupharma Brand of Spironolactone
BIDD:PXR0071
BPBio1_000194
BRD-K90027355-001-03-4
BRN 0057767
BSPBio_000176
C07310
C24H32O4S
CHEBI:428201
CHEBI:45692
CHEBI:9241
CHEMBL1393
CID5833
CPD000471892
Cardel Brand of Spironolactone
D00443
D013148
DB00421
Deverol
Dexo Brand of Spironolactone
Diatensec
Dira
Duraspiron
EINECS 200-133-6
Espironolactona
Espironolactona Alter
Espironolactona Mundogen
Espironolactona [INN-Spanish]
Euteberol
Flumach
Frumikal
Generosan Brand of Spironolactone
HMS1568I18
HMS2090N21
HSDB 3184
Hormosan Brand of Spironolactone
I06-1970
Jenapharm Brand of Spironolactone
Jenaspiron
LS-118614
LT00772287
Lacalmin
Lacdene
Laractone
MLS001074672
MLS001333253
MLS001333254
MLS002153245
MLS002207058
Mayoly-Spindler Brand of Spironolactone
Melarcon
Merck dura Brand of Spironolactone
Mundogen Brand of Spironolactone
NCGC00164397-01
 
NCGC00164397-02
NSC 150399
NSC150399
Nefurofan
Novo Spiroton
Novo-Spiroton
NovoSpiroton
Novopharm Brand of Spironolactone
Osyrol
Pfizer Brand of Spironolactone
Pharmafrid Brand of Spironolactone
Practon
Prestwick0_000128
Prestwick1_000128
Prestwick2_000128
Prestwick3_000128
Roche Brand of Spironolactone
S0260
S3378_SIGMA
SAM002264648
SC 9420
SC-9420
SC9420
SMR000471892
SNL
SPBio_002115
Sagisal
Searle Brand of Spironolactone
Sincomen
Spiractin
Spiresis
Spiretic
Spiridon
Spiro L.U.T.
Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan)
Spiro-Tablinen
Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan]
Spirobeta
Spiroctan
Spiroctanie
Spiroderm
Spirogamma
Spirolactone
Spirolakton
Spirolang
Spirolone
Spirone
Spirono Isis
Spirono-Isis
Spironocompren
Spironolactone
Spironolactone (JP15/USP/INN)
Spironolactone A
Spironolactone [BAN:INN:JAN]
Spironolactone [INN:BAN:JAN]
Spironolactonum
Spironolactonum [INN-Latin]
Spironolattone
Spironolattone [DCIT]
Spironone
Spirospare
Sprioderm
Supra-puren
Suracton
UNII-27O7W4T232
Uractone
Urusonin
Veroshpiron
Verospiron
Verospirone
Verospirone Opianin
WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ
Worwag Brand of Spironolactone
Xenalon
ZINC03861599
betapharm Brand of Spironolactone
ct Arzneimittel Brand of Spironolactone
ct-Arzneimittel Brand of Spironolactone
spiro von ct
spironolactone
spironolattone
von ct, spiro
14
Nitric OxideapprovedPhase 461710102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
15
Uric Acidexperimental, investigationalPhase 414169-93-21175
Synonyms:
1H-Purine-2,6,8-triol
2,6,8-Trihydroxypurine
2,6,8-Trioxopurine
2,6,8-Trioxypurine
 
7,9-dihydro-1H-purine-2,6,8(3H)-trione
Lithate
Lithic acid
Purine-2,6,8(1H,3H,9H)-trione
Urate
Uric acid
16Insulin, Globin ZincPhase 44645
17Sodium Channel BlockersPhase 4, Phase 21593
18Natriuretic AgentsPhase 4, Phase 31697
19Diuretics, Potassium SparingPhase 4, Phase 3, Phase 21917
20insulinPhase 44646
21Adrenergic beta-AntagonistsPhase 4, Phase 3, Phase 21193
22Sodium Chloride Symporter InhibitorsPhase 4452
23diureticsPhase 4, Phase 3, Phase 21418
24Calcium, DietaryPhase 4, Phase 3, Phase 25713
25Adrenergic alpha-AntagonistsPhase 4739
26calcium channel blockersPhase 4, Phase 21985
27Antihypertensive AgentsPhase 4, Phase 3, Phase 24207
28Adrenergic AntagonistsPhase 4, Phase 3, Phase 21573
29Anti-Arrhythmia AgentsPhase 4, Phase 33093
30Adrenergic AgentsPhase 4, Phase 3, Phase 2, Phase 15352
31Adrenergic alpha-1 Receptor AntagonistsPhase 4480
32Angiotensin II Type 1 Receptor BlockersPhase 4, Phase 31091
33Angiotensin Receptor AntagonistsPhase 4, Phase 31191
34AngiotensinogenPhase 4, Phase 31177
35Vasodilator AgentsPhase 4, Phase 3, Phase 23543
36
Angiotensin IIPhase 4, Phase 3117868521-88-0, 11128-99-765143, 172198
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
37Angiotensin-Converting Enzyme InhibitorsPhase 4, Phase 3, Phase 2724
38Neurotransmitter AgentsPhase 4, Phase 3, Phase 2, Phase 118340
39Natriuretic Peptide, BrainPhase 4182
40AntimetabolitesPhase 4, Phase 3, Phase 1, Phase 212054
41AntioxidantsPhase 4, Phase 1, Phase 23050
42Antirheumatic AgentsPhase 4, Phase 1, Phase 210956
43Hydroxymethylglutaryl-CoA Reductase InhibitorsPhase 4, Phase 31998
44HormonesPhase 4, Phase 314415
45Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 313168
46Hormone AntagonistsPhase 4, Phase 313180
47Lipid Regulating AgentsPhase 4, Phase 32766
48Anticholesteremic AgentsPhase 4, Phase 32025
49Hypolipidemic AgentsPhase 4, Phase 32785
50Protective AgentsPhase 4, Phase 1, Phase 27443

Interventional clinical trials:

(show top 50)    (show all 198)
idNameStatusNCT IDPhase
1Study of Qiliqiangxin Capsule to Treat Dilated CardiomyopathyUnknown statusNCT01293903Phase 4
2Danish ICD Study in Patients With Dilated CardiomyopathyUnknown statusNCT00542945Phase 4
3Therapy With Verapamil or Carvedilol in Chronic Heart FailureUnknown statusNCT00374465Phase 4
4Regression of Fatty Heart by Valsartan TherapyUnknown statusNCT00745953Phase 4
5Identification of Carnitine-Responsive CardiomyopathyUnknown statusNCT01904396Phase 4
6Coenzyme Q10 Supplementation in Children With Idiopathic Dilated CardiomyopathyCompletedNCT02115581Phase 4
7Supramaximal Titrated Inhibition of RAAS in Dilated CardiomyopathyCompletedNCT01917149Phase 4
8Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human HeartCompletedNCT01798992Phase 4
9ACC - Atrial Contribution to CRTCompletedNCT00180323Phase 4
10Spanish Atrial Fibrillation And Resynchronization StudyCompletedNCT01181414Phase 4
11A Randomized Trial of Carvedilol in Chronic Chagas CardiomyopathyCompletedNCT01557140Phase 4
12Effects of Allopurinol on Diastolic Function in Chronic Heart Failure PatientsCompletedNCT00477789Phase 4
13Effects of Early Statin Treatment After Acute Myocardial Infarction (AMI) in Japanese PatientsCompletedNCT00128024Phase 4
14Sleep Apnea-hypopnea Syndrome (SAHS) and Ventricular ArrhythmiasCompletedNCT00765713Phase 4
15(MitraClip in Non-Responders to Cardiac Resynchronization Therapy)RecruitingNCT02592889Phase 4
16Pulse Reduction On Beta-blocker and Ivabradine TherapyRecruitingNCT02973594Phase 4
17Effect of Aldosterone on Energy Starvation in Heart FailureActive, not recruitingNCT00574119Phase 4
18Efficacy of Implantable Cardioverter Defibrillator in Patients With Non-ischemic Systolic Heart Failure on MortalityActive, not recruitingNCT00541268Phase 4
19NORDIC: Nitric Oxide-Derived Oxidants and Regional Endothelial and Diastolic Dysfunction in Dilated CardiomyopathyTerminatedNCT00293137Phase 4
20Cardiac Sarcoidosis Response To Steroids TrialWithdrawnNCT01210677Phase 4
21Cell Therapy In Dilated CardiomyopathyCompletedNCT00333827Phase 3
22Autologous Transplantation of Bone Marrow Mononuclear Stem-Cells for Dilated CardiomyopathyCompletedNCT00743639Phase 2, Phase 3
23Honey in Idiopathic Dilated CardiomyopathyCompletedNCT02987322Phase 2, Phase 3
24PUFAs and Left Ventricular Function in Heart FailureCompletedNCT01223703Phase 3
25A Randomized, Controlled Study to Evaluate Algisyl-LVR™ as a Method of Left Ventricular Augmentation for Heart FailureCompletedNCT01311791Phase 2, Phase 3
26Effect of Rosuvastatin on Left Ventricular RemodelingCompletedNCT00505154Phase 3
27The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow DistributionCompletedNCT00741156Phase 3
28Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan SyndromeCompletedNCT00723801Phase 3
29Infusion Intracoronary of Mononuclear Autologous Adult no Expanded Stem Cells of Bone Marrow on Functional Recovery in Patients With Idiopathic Dilated Cardiomyopathy and Heart Failure.RecruitingNCT02033278Phase 2, Phase 3
30Repetitive Intramyocardial CD34+ Cell Therapy in Dilated Cardiomyopathy (REMEDIUM)RecruitingNCT02248532Phase 2, Phase 3
31Continues Positive Airway Pressure Treatment for Patients With Dilated Cardiomyopathy and Obstructive Sleep ApneaRecruitingNCT02989181Phase 3
32PHOspholamban RElated CArdiomyopathy STudy - InterventionRecruitingNCT01857856Phase 3
33CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY)RecruitingNCT02369978Phase 2, Phase 3
34Orodispersible Minitablets of Enalapril in Children With Heart Failure Due to Dilated CardiomyopathyNot yet recruitingNCT02652728Phase 2, Phase 3
35Follow-up Safety Trial in Children With Chronic Heart Failure Therapy Receiving Orodispersible Minitablets of EnalaprilNot yet recruitingNCT02654678Phase 2, Phase 3
36PREclinical Mutation CARriers From Families With DIlated Cardiomyopathy and ACE InhibitorsTerminatedNCT01583114Phase 3
37Cell Therapy in Chagas CardiomyopathyTerminatedNCT00349271Phase 3
38Mental Stress Reduction in Defibrillator PatientsTerminatedNCT00624520Phase 3
39Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart FailureTerminatedNCT00608140Phase 3
40Intramuscular Injection of Mesenchymal Stem Cell for Treatment of Children With Idiopathic Dilated CardiomyopathyUnknown statusNCT01219452Phase 1, Phase 2
41A Pilot Trial of Ranolazine to Treat Patients With Dilated CardiomyopathyUnknown statusNCT02133911Phase 2
42Intracoronary Autologous Mesenchymal Stem Cells Implantation in Patients With Ischemic Dilated CardiomyopathyUnknown statusNCT01720888Phase 2
43Study of the Acute Effects of Triheptanoin in Heart FailureUnknown statusNCT01787851Phase 1, Phase 2
44Safety and Efficacy Study of Stem Cell Transplantation to Treat Dilated CardiomyopathyCompletedNCT00629018Phase 2
45Use of Ixmyelocel-T (Formerly Cardiac Repair Cell [CRC] Treatment) in Patients With Heart Failure Due to Dilated Cardiomyopathy (IMPACT-DCM)CompletedNCT00765518Phase 2
46Use of Ixmyelocel-T (Formerly Catheter-based Cardiac Repair Cell [CRC]) Treatment in Patients With Heart Failure Due to Dilated CardiomyopathyCompletedNCT01020968Phase 2
47Intracoronary Infusion of Autologous Bone Marrow Cells for Treatment of Idiopathic Dilated CardiomyopathyCompletedNCT00629096Phase 2
48Safety and Efficacy Study of Intramyocardial Stem Cell Therapy in Patients With Dilated CardiomyopathyCompletedNCT01350310Phase 2
49Bone Marrow Derived Adult Stem Cells for Dilated CardiomyopathyCompletedNCT01302171Phase 2
50Autologous Transplantation of Bone Marrow Mononuclear Stem-Cells by Mini-ThoracotomyCompletedNCT00615394Phase 1, Phase 2

Search NIH Clinical Center for Dilated Cardiomyopathy

Inferred drug relations via UMLS68/NDF-RT46:

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Dilated Cardiomyopathy cell therapies at LifeMap Discovery.

Genetic Tests for Dilated Cardiomyopathy

About this section

Genetic tests related to Dilated Cardiomyopathy:

id Genetic test Affiliating Genes
1 Primary Dilated Cardiomyopathy27
2 Dilated Cardiomyopathy27 24 VCL
3 Familial Dilated Cardiomyopathy27
4 Cardiomyopathy, Dilated27

Anatomical Context for Dilated Cardiomyopathy

About this section

MalaCards organs/tissues related to Dilated Cardiomyopathy:

36
Heart, Bone, Lung, Liver, Monocytes, Testes, Brain

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Dilated Cardiomyopathy:
id TissueAnatomical CompartmentCell Relevance
1 HeartMyocardiumCardiomyocytes Affected by disease
2 HeartLeft VentricleCardiomyocytes Potential therapeutic candidate, affected by disease
3 BloodCord BloodMesenchymal Stem Cells Potential therapeutic candidate
4 Umbilical CordWharton's JellyMesenchymal Stem Cells Potential therapeutic candidate

Publications for Dilated Cardiomyopathy

About this section

Articles related to Dilated Cardiomyopathy:

(show top 50)    (show all 1582)
idTitleAuthorsYear
1
Dilated Cardiomyopathy and Hydroxychloroquine-induced Phospholipidosis: From Curvilinear Bodies to Clinical Suspicion. (28528883)
2017
2
Renin-angiotensin system gene polymorphisms as potential modifiers of hypertrophic and dilated cardiomyopathy phenotypes. (28120210)
2017
3
Genotype-specific pathogenic effects in human dilated cardiomyopathy. (28436080)
2017
4
Inhibition of miR-208b improves cardiac function in titin-based dilated cardiomyopathy. (28065693)
2017
5
The long non-coding RNA H19 promotes cardiomyocyte apoptosis in dilated cardiomyopathy. (28430627)
2017
6
Dilated Cardiomyopathy in a 2-Year-Old Infant. (28062634)
2017
7
In-depth proteomic profiling of left ventricular tissues in human end-stage dilated cardiomyopathy. (28427148)
2017
8
Primary Prevention of Sudden Arrhythmic Death in Dilated Cardiomyopathy: Current Guidelines and Risk Stratification. (28034375)
2017
9
Truncating mutations on myofibrillar myopathies causing genes as prevalent molecular explanations on patients with dilated cardiomyopathy. (28436997)
2017
10
12-month patterns of serum markers of collagen synthesis, transforming growth factor and connective tissue growth factor are similar in new-onset and chronic dilated cardiomyopathy in patients both with and without cardiac fibrosis. (28460256)
2017
11
Variable clinical course of identical twin neonates with AlstrAPm syndrome presenting coincidentally with dilated cardiomyopathy. (28407410)
2017
12
Sokolow-Lyon voltage is suitable for monitoring improvement in cardiac function and prognosis of patients with idiopathic dilated cardiomyopathy. (28471539)
2017
13
The Hemodynamic Effects and Safety of Repetitive Levosimendan Infusions on Children With Dilated Cardiomyopathy. (28033083)
2017
14
Expression of Bcl-2 and microRNAs in cardiac tissues of patients with dilated cardiomyopathy. (27922664)
2017
15
Titin Truncating Variants in Dilated Cardiomyopathy - Prevalence and Genotype-Phenotype Correlations. (28045975)
2017
16
Reply: Risk Stratification in Dilated Cardiomyopathy: Is the Arrhythmogenic Substrate Stable Over Time? (28449802)
2017
17
Clinical significance of cathepsin L and cathepsin B in dilated cardiomyopathy. (28074340)
2017
18
Distribution of strain patterns in children with dilated cardiomyopathy. (28480564)
2017
19
Contrast-enhanced T1 mapping-based extracellular volume fraction independently predicts clinical outcome in patients with non-ischemic dilated cardiomyopathy: a prospective cohort study. (28439651)
2017
20
Truncating Variants in Titin Independently Predict Early Arrhythmias in Patients With Dilated Cardiomyopathy. (28494986)
2017
21
Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy. (28296976)
2017
22
Dilated cardiomyopathy associated with elephant trunk in Loeys-Dietz syndrome. (28082467)
2017
23
Genetic epidemiology of titin-truncating variants in the etiology of dilated cardiomyopathy. (28510119)
2017
24
Tacrolimus-Associated Dilated Cardiomyopathy in Adult Patient After Orthotopic Liver Transplant. (28508004)
2017
25
Decreased WNT/I^-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene. (28069793)
2017
26
Risk Stratification in Dilated Cardiomyopathy: Is the Arrhythmogenic Substrate Stable Over Time? (28449801)
2017
27
E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy. (28085920)
2017
28
Comparison of clinical outcomes in peripartum cardiomyopathy and age-matched dilated cardiomyopathy: A 15-year nationwide population-based study in Asia. (28489799)
2017
29
Altered myocyte contractility and calcium homeostasis in alpha-myosin heavy chain point mutations linked to familial dilated cardiomyopathy. (28088328)
2017
30
Recessive TAF1A mutations reveal ribosomopathy in siblings with end-stage pediatric dilated cardiomyopathy. (28472305)
2017
31
Early and frequent defibrillator discharge in patients with cardiac sarcoidosis compared with patients with idiopathic dilated cardiomyopathy. (28438355)
2017
32
Graded" epidural anesthesia for renal transplant in a patient with dilated cardiomyopathy and severe left ventricle systolic dysfunction. (28442964)
2017
33
The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy. (28474304)
2017
34
Role of cardiac TBX20 in dilated cardiomyopathy. (26895318)
2016
35
Genetic causes of dilated cardiomyopathy. (27634407)
2016
36
Addison's Disease and Dilated Cardiomyopathy: A Case Report and Review of the Literature. (28003914)
2016
37
A novel overlapping phenotype characterized by lipodystrophy, mandibular dysplasia, and dilated cardiomyopathy associated with a new mutation in the LMNA gene. (26922292)
2016
38
Imaging and 1-day kinetics of intracoronary stem cell transplantation in patients with idiopathic dilated cardiomyopathy. (27179747)
2016
39
Predictors of Sudden Cardiac Death in Doberman Pinschers with Dilated Cardiomyopathy. (27177626)
2016
40
A novel GJA1 mutation causing familial oculodentodigital dysplasia with dilated cardiomyopathy and arrhythmia. (28491627)
2016
41
Genetic bases of dilated cardiomyopathy. (27661610)
2016
42
A Heterozygous ZMPSTE24 Mutation Associated with Severe Metabolic Syndrome, Ectopic Fat Accumulation, and Dilated Cardiomyopathy. (27120622)
2016
43
The immunohistochemical evaluation of selected markers in the left atrium of dogs with end-stage dilated cardiomyopathy and myxomatous mitral valve disease - a preliminary study. (27980728)
2016
44
Late Gadolinium Enhancement and theA Risk for Ventricular Arrhythmias or SuddenA Death in Dilated Cardiomyopathy: Systematic Review and Meta-Analysis. (28017348)
2016
45
Association between 1019C/T polymorphism in the connexin 37 gene and dilated cardiomyopathy. (25501978)
2016
46
Metabolism of arachidonic acid by the cytochrome P450 enzyme in patients with chronic Keshan disease and dilated cardiomyopathy. (26893848)
2016
47
A Dilated Cardiomyopathy Revealing a Neuroblastoma: Which Link? (27571126)
2016
48
Non-invasive Model-Based Assessment of Passive Left-Ventricular Myocardial Stiffness in Healthy Subjects and in Patients with Non-ischemic Dilated Cardiomyopathy. (27605213)
2016
49
Functional Class in Children with Idiopathic Dilated Cardiomyopathy. A pilot Study. (27168472)
2016
50
Variants of resistin gene and the risk of idiopathic dilated cardiomyopathy in Pakistan. (27114921)
2016

Variations for Dilated Cardiomyopathy

About this section

Clinvar genetic disease variations for Dilated Cardiomyopathy:

5 (show all 84)
id Gene Variation Type Significance SNP ID Assembly Location
1TNNT2NM_ 001001430.2(TNNT2): c.421C> T (p.Arg141Trp)SNVPathogenic/ Likely pathogenicrs74315379GRCh37Chr 1, 201333464: 201333464
2TTNNM_ 001256850.1(TTN): c.2926T> C (p.Trp976Arg)SNVPathogenicrs267607155GRCh37Chr 2, 179647707: 179647707
3PLNNM_ 002667.4(PLN): c.25C> T (p.Arg9Cys)SNVPathogenicrs111033559GRCh37Chr 6, 118880109: 118880109
4PLNNM_ 002667.4(PLN): c.116T> G (p.Leu39Ter)SNVPathogenic/ Likely pathogenicrs111033560GRCh37Chr 6, 118880200: 118880200
5MYH7NM_ 000257.3(MYH7): c.1594T> C (p.Ser532Pro)SNVPathogenicrs121913642GRCh37Chr 14, 23897088: 23897088
6DSPNM_ 004415.3(DSP): c.2131_ 2132delAG (p.Ser711Cysfs)deletionPathogenic/ Likely pathogenicrs587782927GRCh37Chr 6, 7574319: 7574320
7LMNANM_ 170707.3(LMNA): c.16C> T (p.Gln6Ter)SNVPathogenicrs61046466GRCh37Chr 1, 156084725: 156084725
8LMNANM_ 170707.3(LMNA): c.585C> G (p.Asn195Lys)SNVPathogenicrs28933091GRCh37Chr 1, 156104265: 156104265
9LMNANM_ 170707.3(LMNA): c.608A> G (p.Glu203Gly)SNVPathogenicrs28933092GRCh37Chr 1, 156104288: 156104288
10LMNANM_ 170707.3(LMNA): c.1445G> A (p.Arg482Gln)SNVPathogenicrs11575937GRCh37Chr 1, 156106776: 156106776
11LMNANM_ 170707.3(LMNA): c.481G> A (p.Glu161Lys)SNVPathogenic/ Likely pathogenicrs28933093GRCh37Chr 1, 156100532: 156100532
12TSFMNM_ 005726.5(TSFM): c.856C> T (p.Gln286Ter)SNVPathogenicrs201754030GRCh37Chr 12, 58190244: 58190244
13LMNANM_ 170707.3(LMNA): c.1086delT (p.Leu363Trpfs)deletionPathogenicrs58389804GRCh37Chr 1, 156105841: 156105841
14MYH7NM_ 000257.3(MYH7): c.2710C> T (p.Arg904Cys)SNVPathogenicrs727503253GRCh37Chr 14, 23893328: 23893328
15TTNNM_ 001256850.1(TTN): c.89257delCinsTCTAGCAG (p.Pro29753Serfs)indelPathogenic/ Likely pathogenicrs727503547GRCh37Chr 2, 179412173: 179412173
16TTNNM_ 001256850.1(TTN): c.76963delG (p.Glu25655Lysfs)deletionPathogenic/ Likely pathogenicrs727503557GRCh37Chr 2, 179428973: 179428973
17TTNNM_ 001256850.1(TTN): c.66398G> A (p.Trp22133Ter)SNVPathogenic/ Likely pathogenicrs727503567GRCh37Chr 2, 179439538: 179439538
18TTNNM_ 001256850.1(TTN): c.63526C> T (p.Arg21176Ter)SNVPathogenic/ Likely pathogenicrs371678190GRCh37Chr 2, 179442793: 179442793
19TTNNM_ 001256850.1(TTN): c.57294T> A (p.Tyr19098Ter)SNVPathogenic/ Likely pathogenicrs727503586GRCh37Chr 2, 179454235: 179454235
20TTNNM_ 001256850.1(TTN): c.48730G> T (p.Glu16244Ter)SNVPathogenic/ Likely pathogenicrs727503607GRCh37Chr 2, 179470369: 179470369
21DSPNM_ 004415.3(DSP): c.3799C> T (p.Arg1267Ter)SNVPathogenic/ Likely pathogenicrs121912997GRCh37Chr 6, 7580222: 7580222
22TTNNM_ 001267550.2(TTN): c.72669delT (p.Asp24224Ilefs)deletionPathogenic/ Likely pathogenicrs727504531GRCh37Chr 2, 179438190: 179438190
23TTNNM_ 001256850.1(TTN): c.94071delA (p.Lys31357Asnfs)deletionPathogenic/ Likely pathogenicrs727504535GRCh37Chr 2, 179403562: 179403562
24TTNNM_ 001256850.1(TTN): c.76955_ 76956delTT (p.Phe25652Cysfs)deletionPathogenic/ Likely pathogenicrs727504660GRCh38Chr 2, 178564253: 178564254
25TTNNM_ 001256850.1(TTN): c.44725+2delTdeletionPathogenic/ Likely pathogenicrs727504851GRCh38Chr 2, 178613159: 178613159
26TTNNM_ 001256850.1(TTN): c.86916dupA (p.Val28973Serfs)duplicationPathogenic/ Likely pathogenicrs730880365GRCh38Chr 2, 178549999: 178549999
27LMNANM_ 170707.3(LMNA): c.1609-1G> ASNVPathogenic/ Likely pathogenicrs111569862GRCh37Chr 1, 156107444: 156107444
28TTNNM_ 001256850.1(TTN): c.75793C> T (p.Arg25265Ter)SNVPathogenic/ Likely pathogenicrs727505284GRCh37Chr 2, 179430143: 179430143
29TTNNM_ 001256850.1(TTN): c.92569+1G> CSNVPathogenic/ Likely pathogenicrs727505319GRCh37Chr 2, 179406990: 179406990
30LMNANM_ 170707.3(LMNA): c.710T> C (p.Phe237Ser)SNVPathogenicrs730880132GRCh38Chr 1, 156134875: 156134875
31TNNT2NM_ 001001430.2(TNNT2): c.613C> T (p.Arg205Trp)SNVPathogenic/ Likely pathogenicrs45586240GRCh37Chr 1, 201331117: 201331117
32TTNNM_ 001267550.2(TTN): c.67495C> T (p.Arg22499Ter)SNVPathogenic/ Likely pathogenicrs574660186GRCh37Chr 2, 179444429: 179444429
33MYH7NM_ 000257.3(MYH7): c.732+1G> ASNVPathogenic/ Likely pathogenicrs730880850GRCh38Chr 14, 23431584: 23431584
34MYH7NM_ 000257.3(MYH7): c.842G> C (p.Arg281Thr)SNVPathogenicrs730880856GRCh37Chr 14, 23900163: 23900163
35PSEN1NM_ 000021.3(PSEN1): c.998A> G (p.Asp333Gly)SNVPathogenic/ Likely pathogenicrs121917809GRCh37Chr 14, 73678519: 73678519
36DSG2NM_ 001943.4(DSG2): c.3059_ 3062delAGAG (p.Glu1020Alafs)deletionPathogenic/ Likely pathogenicrs794728096GRCh38Chr 18, 31546445: 31546448
37LMNANM_ 170707.3(LMNA): c.859delG (p.Ala287Leufs)deletionPathogenic/ Likely pathogenicrs59564495GRCh37Chr 1, 156105026: 156105026
38TTNNM_ 001256850.1(TTN): c.69415C> T (p.Arg23139Ter)SNVPathogenic/ Likely pathogenicrs794729285GRCh37Chr 2, 179436521: 179436521
39TTNNM_ 001256850.1(TTN): c.94066+1G> ASNVPathogenic/ Likely pathogenicrs112240298GRCh37Chr 2, 179403672: 179403672
40TTNNM_ 001256850.1(TTN): c.48470delG (p.Gly16157Alafs)deletionPathogenic/ Likely pathogenicrs794729324GRCh37Chr 2, 179471936: 179471936
41TTNNM_ 001256850.1(TTN): c.58102C> T (p.Arg19368Ter)SNVPathogenic/ Likely pathogenicrs368452607GRCh37Chr 2, 179453427: 179453427
42TTNNM_ 003319.4(TTN): c.57895C> T (p.Arg19299Ter)SNVPathogenic/ Likely pathogenicrs770038577GRCh37Chr 2, 179425769: 179425769
43TTNNM_ 001256850.1(TTN): c.44423-1G> ASNVPathogenic/ Likely pathogenicrs869312070GRCh38Chr 2, 178613938: 178613938
44TTNNM_ 001267550.2(TTN): c.76115dupA (p.Asn25372Lysfs)duplicationPathogenic/ Likely pathogenicrs774604740GRCh37Chr 2, 179434744: 179434744
45TTNNM_ 001267550.2(TTN): c.83515C> T (p.Arg27839Ter)SNVPathogenic/ Likely pathogenicrs869312118GRCh38Chr 2, 178562617: 178562617
46TTNNM_ 001256850.1(TTN): c.81514G> T (p.Glu27172Ter)SNVPathogenic/ Likely pathogenicrs868494032GRCh38Chr 2, 178559695: 178559695
47BAG3NM_ 004281.3(BAG3): c.925C> T (p.Arg309Ter)SNVPathogenicrs869248137GRCh37Chr 10, 121435991: 121435991
48MYBPC3NM_ 000256.3(MYBPC3): c.2504delG (p.Arg835Profs)deletionPathogenicrs876657704GRCh38Chr 11, 47337489: 47337489
49TNNT2NM_ 001001430.2(TNNT2): c.517C> T (p.Arg173Trp)SNVPathogenic/ Likely pathogenicrs727503512GRCh38Chr 1, 201363349: 201363349
50RBM20NM_ 001134363.2(RBM20): c.1913C> T (p.Pro638Leu)SNVPathogenicrs267607003GRCh37Chr 10, 112572068: 112572068
51RBM20NM_ 001134363.2(RBM20): c.1906C> A (p.Arg636Ser)SNVPathogenic/ Likely pathogenicrs267607002GRCh37Chr 10, 112572061: 112572061
52RBM20NM_ 001134363.2(RBM20): c.1907G> A (p.Arg636His)SNVPathogenic/ Likely pathogenicrs267607004GRCh37Chr 10, 112572062: 112572062
53BAG3NM_ 004281.3(BAG3): c.367C> T (p.Arg123Ter)SNVPathogenic/ Likely pathogenicrs387906875GRCh37Chr 10, 121429549: 121429549
54TPM1NM_ 001018005.1(TPM1): c.688G> A (p.Asp230Asn)SNVPathogenicrs199476317GRCh37Chr 15, 63354462: 63354462
55SCN5ANM_ 198056.2(SCN5A): c.665G> A (p.Arg222Gln)SNVPathogenicrs45546039GRCh37Chr 3, 38655272: 38655272
56MYH7NM_ 000257.3(MYH7): c.1106G> A (p.Arg369Gln)SNVLikely pathogenicrs397516089GRCh37Chr 14, 23899016: 23899016
57MYH7NM_ 000257.3(MYH7): c.5401G> A (p.Glu1801Lys)SNVLikely pathogenicrs397516248GRCh37Chr 14, 23884362: 23884362
58MYH7NM_ 000257.3(MYH7): c.5740G> A (p.Glu1914Lys)SNVLikely pathogenicrs397516254GRCh37Chr 14, 23883018: 23883018
59TNNI3NM_ 000363.4(TNNI3): c.544G> A (p.Glu182Lys)SNVPathogenicrs397516355GRCh37Chr 19, 55665403: 55665403
60TNNT2NM_ 000364.3(TNNT2): c.422G> A (p.Arg141Gln)SNVPathogenicrs397516464GRCh37Chr 1, 201333493: 201333493
61TNNT2NM_ 001001430.2(TNNT2): c.629_ 631delAGA (p.Lys210del)deletionPathogenicrs45578238GRCh37Chr 1, 201331099: 201331101
62DESNM_ 001927.3(DES): c.38C> T (p.Ser13Phe)SNVPathogenicrs62636495GRCh37Chr 2, 220283222: 220283222
63PLNNM_ 002667.4(PLN): c.40_ 42delAGA (p.Arg14del)deletionPathogenicrs397516784GRCh37Chr 6, 118880124: 118880126
64DSPNM_ 004415.3(DSP): c.1146delT (p.Phe382Leufs)deletionPathogenicrs397516913GRCh37Chr 6, 7568019: 7568019
65TTNNM_ 001256850.1(TTN): c.54282delG (p.Glu18094Aspfs)deletionPathogenic/ Likely pathogenicrs397517643GRCh37Chr 2, 179457641: 179457641
66TTNNM_ 001256850.1(TTN): c.56953C> T (p.Arg18985Ter)SNVPathogenic/ Likely pathogenicrs72646846GRCh37Chr 2, 179454576: 179454576
67LDB3NM_ 001080114.1(LDB3): c.494C> T (p.Ala165Val)SNVPathogenicrs121908334GRCh37Chr 10, 88446975: 88446975
68TTNNM_ 001267550.2(TTN): c.71602C> T (p.Arg23868Ter)SNVPathogenic/ Likely pathogenicrs397517689GRCh37Chr 2, 179439257: 179439257
69TTNNM_ 001267550.2(TTN): c.86821+2T> ASNVPathogenic/ Likely pathogenicrs397517735GRCh37Chr 2, 179424036: 179424036
70TTNNM_ 001256850.1(TTN): c.88974delT (p.Phe29658Leufs)deletionPathogenic/ Likely pathogenicrs397517758GRCh37Chr 2, 179412456: 179412456
71LMNANM_ 170707.3(LMNA): c.1129C> T (p.Arg377Cys)SNVPathogenic/ Likely pathogenicrs397517889GRCh37Chr 1, 156105884: 156105884
72LMNANM_ 005572.3(LMNA): c.1526dupC (p.Thr510Tyrfs)duplicationPathogenic/ Likely pathogenicrs58013325GRCh37Chr 1, 156106941: 156106941
73LMNANM_ 170707.3(LMNA): c.1621C> T (p.Arg541Cys)SNVPathogenicrs56984562GRCh37Chr 1, 156107457: 156107457
74LMNANM_ 170707.3(LMNA): c.348dupG (p.Lys117Glufs)duplicationPathogenicrs267607646GRCh37Chr 1, 156085057: 156085057
75LMNANM_ 170707.3(LMNA): c.607G> A (p.Glu203Lys)SNVPathogenicrs61195471GRCh37Chr 1, 156104287: 156104287
76LMNANM_ 005572.3(LMNA): c.673C> T (p.Arg225Ter)SNVPathogenicrs60682848GRCh37Chr 1, 156104629: 156104629
77LMNANM_ 170707.3(LMNA): c.799T> C (p.Tyr267His)SNVPathogenicrs267607593GRCh37Chr 1, 156104755: 156104755
78LMNANM_ 170707.3(LMNA): c.958delC (p.Leu320Phefs)deletionPathogenicrs397517915GRCh37Chr 1, 156105713: 156105713
79LMNANM_ 170707.3(LMNA): c.961C> T (p.Arg321Ter)SNVPathogenicrs267607554GRCh37Chr 1, 156105716: 156105716
80TCAPNM_ 003673.3(TCAP): c.157C> T (p.Gln53Ter)SNVPathogenic/ Likely pathogenicrs104894655GRCh37Chr 17, 37822015: 37822015
81LMNANM_ 170707.3(LMNA): c.1294C> T (p.Gln432Ter)SNVPathogenic/ Likely pathogenicrs267607618GRCh37Chr 1, 156106141: 156106141
82LMNANM_ 170707.3(LMNA): c.244G> A (p.Glu82Lys)SNVPathogenicrs59270054GRCh37Chr 1, 156084953: 156084953
83SCN5ANM_ 198056.2(SCN5A): c.2440C> T (p.Arg814Trp)SNVPathogenic/ Likely pathogenicrs199473161GRCh37Chr 3, 38627529: 38627529
84CSRP3NM_ 003476.4(CSRP3): c.136A> C (p.Ser46Arg)SNVPathogenic/ Likely pathogenicrs137852765GRCh37Chr 11, 19209828: 19209828

Expression for genes affiliated with Dilated Cardiomyopathy

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Search GEO for disease gene expression data for Dilated Cardiomyopathy.

Pathways for genes affiliated with Dilated Cardiomyopathy

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Pathways related to Dilated Cardiomyopathy according to KEGG:

34
id Name KEGG Source Accession
1Dilated cardiomyopathyhsa05414

Pathways related to Dilated Cardiomyopathy according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
10.6ACTC1, DES, DMD, LMNA, MYBPC3, MYH7
2
Show member pathways
10.6DES, DMD, MYBPC3, PLN, SCN5A, TNNI3
3
Show member pathways
10.5ACTC1, MYH7, PLN, SCN5A, TNNI3, TNNT2
410.5ACTC1, DES, DMD, MYBPC3, TNNI3, TNNT2
510.5ACTC1, DES, LMNA, TNNI3, TNNT2, TPM1
610.5ACTC1, MYH7, TNNI3, TNNT2, TPM1
710.5DSP, LMNA, PLN, SCN5A
810.5DES, TNNI3, TNNT2
910.5ACTC1, SCN5A, TNNI3, TNNT2
10
Show member pathways
10.5DES, DMD, DSP, LMNA, SGCD, VCL

GO Terms for genes affiliated with Dilated Cardiomyopathy

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Cellular components related to Dilated Cardiomyopathy according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1cardiac myofibrilGO:009751211.2DES, MYBPC3, TNNI3, TNNT2
2cardiac Troponin complexGO:199058411.2TNNI3, TNNT2
3contractile fiberGO:004329211.2DES, TNNI3
4cell-substrate junctionGO:003005511.2DMD, VCL
5costamereGO:004303411.2DMD, VCL
6cytoskeletonGO:000585611.1ACTC1, CSRP3, DES, DMD, DSP, LDB3
7myofibrilGO:003001611.1DMD, MYH7, TNNI3, TNNT2, TPM1
8fascia adherensGO:000591611.1DES, DSP, VCL
9intercalated discGO:001470411.1DES, DSP, SCN5A
10dystrophin-associated glycoprotein complexGO:001601011.1DMD, SGCD
11myosin filamentGO:003298211.1MYBPC3, MYH7
12sarcomereGO:003001711.1ACTC1, CSRP3, MYBPC3, MYH7, TNNI3, TNNT2
13sarcolemmaGO:004238311.1DES, DMD, SCN5A, SGCD
14troponin complexGO:000586111.0TNNI3, TNNT2
15Z discGO:003001810.5BAG3, CSRP3, DES, DMD, LDB3, MYBPC3

Biological processes related to Dilated Cardiomyopathy according to GeneCards Suite gene sharing:

(show all 27)
idNameGO IDScoreTop Affiliating Genes
1cardiac muscle contractionGO:006004811.2ACTC1, CSRP3, DMD, MYBPC3, MYH7, SCN5A
2muscle filament slidingGO:003004911.2ACTC1, DES, DMD, MYBPC3, MYH7, TNNI3
3muscle contractionGO:000693611.2DES, MYH7, TNNT2, TPM1, TTN, VCL
4cardiac muscle hypertrophyGO:000330011.2CSRP3, TTN
5cardiac muscle tissue morphogenesisGO:005500811.2ACTC1, TTN
6cardiac muscle tissue developmentGO:004873811.2CSRP3, PLN, SGCD
7cardiac myofibril assemblyGO:005500311.2ACTC1, CSRP3, TTN
8cellular calcium ion homeostasisGO:000687411.2CSRP3, PLN, TNNI3
9detection of muscle stretchGO:003599511.2CSRP3, TTN
10heart contractionGO:006004711.2ACTC1, SGCD, TNNI3
11intermediate filament organizationGO:004510911.2DES, DSP
12negative regulation of ATPase activityGO:003278011.1PLN, TNNI3, TNNT2
13positive regulation of ATPase activityGO:003278111.1MYBPC3, TNNT2, TPM1
14regulation of heart contractionGO:000801611.1DES, PLN, TNNT2, TPM1
15regulation of cardiac muscle cell contractionGO:008600411.1PLN, SCN5A
16muscle organ developmentGO:000751711.1CSRP3, DMD, SGCD
17regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionGO:001088111.1DMD, PLN
18regulation of muscle contractionGO:000693711.1TNNI3, TNNT2, TPM1
19regulation of heart rateGO:000202711.1DMD, MYH7, SCN5A
20regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088011.0DMD, PLN
21regulation of ryanodine-sensitive calcium-release channel activityGO:006031411.0DMD, PLN
22regulation of the force of heart contractionGO:000202611.0CSRP3, MYH7, PLN
23response to denervation involved in regulation of muscle adaptationGO:001489411.0DMD, SCN5A
24sarcomere organizationGO:004521411.0LDB3, MYBPC3, TPM1, TTN
25skeletal muscle thin filament assemblyGO:003024010.9ACTC1, TTN
26striated muscle contractionGO:000694110.9MYBPC3, MYH7, TNNI3, TTN
27ventricular cardiac muscle tissue morphogenesisGO:005501010.5MYBPC3, MYH7, TNNI3, TNNT2, TPM1

Molecular functions related to Dilated Cardiomyopathy according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1actin bindingGO:000377911.4CSRP3, DMD, MYBPC3, MYH7, TNNI3, TNNT2
2actin filament bindingGO:005101511.3MYBPC3, TNNI3, TPM1, TTN, VCL
3muscle alpha-actinin bindingGO:005137111.3LDB3, MYBPC3, TTN
4cytoskeletal protein bindingGO:000809211.3DES, LDB3, TPM1
5myosin bindingGO:001702211.3ACTC1, DMD, MYBPC3
6actinin bindingGO:004280511.3CSRP3, TTN
7nitric-oxide synthase bindingGO:005099811.3DMD, SCN5A
8dystroglycan bindingGO:000216211.3DMD, VCL
9protein bindingGO:000551511.2BAG3, CSRP3, DES, DMD, DSP, LDB3
10structural constituent of cytoskeletonGO:000520011.0DES, DMD, DSP, TPM1
11structural constituent of muscleGO:000830710.9CSRP3, DMD, MYBPC3, TPM1, TTN
12structural molecule activity conferring elasticityGO:009749310.7MYBPC3, TTN
13troponin C bindingGO:003017210.5TNNI3, TNNT2
14telethonin bindingGO:003143310.5CSRP3, TTN

Sources for Dilated Cardiomyopathy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet