MCID: DLT002
MIFTS: 72

Dilated Cardiomyopathy malady

Categories: Genetic diseases, Rare diseases, Cardiovascular diseases

Aliases & Classifications for Dilated Cardiomyopathy

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Aliases & Descriptions for Dilated Cardiomyopathy:

Name: Dilated Cardiomyopathy 32 10 21 45 22 47 12
Familial Dilated Cardiomyopathy 10 45 23 65
Cardiomyopathy, Dilated 36 24 65
Idiopathic Dilation Cardiomyopathy 10 65
Dilated Cardiomyopathy, Familial 45 24
Primary Dilated Cardiomyopathy 10 24
Congestive Cardiomyopathy 10 23
Dcm 45 40
 
Hypokinetic Dilated Cardiomyopathy, Familial 45
Primary Familial Dilated Cardiomyopathy 23
Cardiomyopathy, Familial Idiopathic 65
Familial Idiopathic Cardiomyopathy 23
Idiopathic Dilated Cardiomyopathy 45
Cardiomyopathy, Familial Dilated 45
Fdc 23

Classifications:



External Ids:

Disease Ontology10 DOID:12930
ICD1027 I42.0
MeSH36 D002311
NCIt42 C84673
UMLS65 C0007193, C1449563, C0340427 C2931157, more

Summaries for Dilated Cardiomyopathy

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NIH Rare Diseases:45 Dilated cardiomyopathy is a disease of the heart muscle which primarily affects the heart's main pumping chamber, the left ventricle. it is the most common type of cardiomyopathy and typically affects those aged 20 to 60. the left ventricle of affected individuals becomes enlarged (dilated) and cannot pump blood to the body with as much force as a healthy heart can. the heart muscle also has difficulty contracting normally, which can lead to irregular heartbeats (arrhythmia), blood clots, or sudden death. over time, the heart becomes weaker and heart failure can occur. while the cause of dilated cardiomyopathy is often unknown (idiopathic), some cases are acquired and roughly half are inherited or familial.  familial dilated cardiomyopathy is most often inherited in an autosomal dominant pattern.  mutations in the ttn gene are found in approximately 20 percent of cases of familial dilated cardioyopathy. last updated: 3/29/2013

MalaCards based summary: Dilated Cardiomyopathy, also known as familial dilated cardiomyopathy, is related to dmd-related dilated cardiomyopathy and ventricular tachycardia, catecholaminergic polymorphic, 1. An important gene associated with Dilated Cardiomyopathy is RBM20 (RNA Binding Motif Protein 20), and among its related pathways are Cardiac Progenitor Differentiation and Cardiac muscle contraction. The drugs inamrinone and inamrinone lactate have been mentioned in the context of this disorder. Affiliated tissues include heart, bone and liver, and related mouse phenotypes are homeostasis/metabolism and mortality/aging.

Disease Ontology:10 An intrinsic cardiomyopathy that results in damage to the myocardium causing the heart to pump blood inefficiently and characterized by an enlarged heart.

Genetics Home Reference:23 Familial dilated cardiomyopathy is a genetic form of heart disease. It occurs when heart (cardiac) muscle becomes stretched out in at least one chamber of the heart, causing the open area of the chamber to become enlarged (dilated). As a result, the heart is unable to pump blood as efficiently as usual. Eventually, all four chambers of the heart become dilated as the cardiac muscle tries to increase the amount of blood being pumped through the heart. However, as the cardiac muscle becomes increasingly thin and weakened, it is less able to pump blood. Over time, this condition results in heart failure.

Wikipedia:68 Dilated cardiomyopathy or DCM is a condition in which the heart becomes enlarged and cannot pump blood... more...

GeneReviews summary for NBK1309

Related Diseases for Dilated Cardiomyopathy

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Diseases in the Cardiomyopathy family:

Cardiomyopathy, Dilated, 1cc Cardiomyopathy, Dilated, 1a
Cardiomyopathy, Dilated, 1v Cardiomyopathy, Dilated, 1d
Cardiomyopathy, Dilated, 1h Cardiomyopathy, Dilated, 1g
Cardiomyopathy, Dilated, 1i Cardiomyopathy, Dilated, 1nn
Cardiomyopathy, Dilated, 1z Cardiomyopathy, Dilated, 1e
Cardiomyopathy, Dilated, 1gg Cardiomyopathy, Dilated, 1l
Cardiomyopathy, Dilated, 1k Cardiomyopathy, Dilated, 1jj
Cardiomyopathy, Dilated, 1p Cardiomyopathy, Dilated, 1j
Cardiomyopathy, Dilated, 2b Cardiomyopathy, Dilated, 1q
Cardiomyopathy, Dilated, 1x Cardiomyopathy, Dilated, 1kk
Cardiomyopathy, Dilated, 1w Cardiomyopathy, Dilated, 1dd
Cardiomyopathy, Dilated, 1hh Cardiomyopathy, Dilated, 1m
Cardiomyopathy, Dilated, 1ii Cardiomyopathy, Dilated, 1o
Cardiomyopathy, Dilated, 1t Cardiomyopathy, Dilated, 1ee
Cardiomyopathy, Dilated, 1u Cardiomyopathy, Dilated, 1r
Cardiomyopathy, Dilated, 1bb Cardiomyopathy, Dilated, 2a
Cardiomyopathy, Dilated, 1ff Cardiomyopathy, Dilated, 3b
dilated cardiomyopathy Lmna-Related Dilated Cardiomyopathy
Cardiomyopathy Due to Anthracyclines Cryab-Related Dilated Cardiomyopathy
Mypn-Related Cardiomyopathy Abcc9-Related Dilated Cardiomyopathy
Actc1-Related Dilated Cardiomyopathy Actn2-Related Dilated Cardiomyopathy
Ankrd1-Related Dilated Cardiomyopathy Bag3-Related Dilated Cardiomyopathy
Csrp3-Related Dilated Cardiomyopathy Des-Related Dilated Cardiomyopathy
Dmd-Related Dilated Cardiomyopathy Dsg2-Related Dilated Cardiomyopathy
Eya4-Related Dilated Cardiomyopathy Fktn-Related Dilated Cardiomyopathy
Gatad1-Related Dilated Cardiomyopathy Lama4-Related Dilated Cardiomyopathy
Ldb3-Related Dilated Cardiomyopathy Mybpc3-Related Dilated Cardiomyopathy
Myh6-Related Dilated Cardiomyopathy Myh7-Related Dilated Cardiomyopathy
Nexn-Related Dilated Cardiomyopathy Pln-Related Dilated Cardiomyopathy
Psen1-Related Dilated Cardiomyopathy Psen2-Related Dilated Cardiomyopathy
Rbm20-Related Dilated Cardiomyopathy Scn5a-Related Dilated Cardiomyopathy
Sgcd-Related Dilated Cardiomyopathy Taz-Related Dilated Cardiomyopathy
Tcap-Related Dilated Cardiomyopathy Tmpo-Related Dilated Cardiomyopathy
Tnnc1-Related Dilated Cardiomyopathy Tnni3-Related Dilated Cardiomyopathy
Tnnt2-Related Dilated Cardiomyopathy Tpm1-Related Dilated Cardiomyopathy
Ttn-Related Dilated Cardiomyopathy Vcl-Related Dilated Cardiomyopathy

Diseases related to Dilated Cardiomyopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 868)
idRelated DiseaseScoreTop Affiliating Genes
1dmd-related dilated cardiomyopathy34.5DMD, TAZ
2ventricular tachycardia, catecholaminergic polymorphic, 133.2RYR2, SCN5A
3myopathy, myofibrillar, 132.9DES, LDB3
4cardiomyopathy, dilated, 1e32.8MYH7, SCN5A
5becker muscular dystrophy31.8DMD, SGCD, TNNT2
6cardiomyopathy, dilated, 1l31.5DMD, SGCD, TTN
7gastric cancer30.7DMD, TNNT2
8inguinal hernia30.4RYR2, SCN5A, TNNT2
9dmd-associated dilated cardiomyopathy12.6
10cardiac conduction disease with or without dilated cardiomyopathy12.6
11familial isolated dilated cardiomyopathy12.5
12dilated cardiomyopathy with woolly hair, keratoderma, and tooth agenesis12.4
13sensorineural deafness with dilated cardiomyopathy12.4
14lmna-related dilated cardiomyopathy12.4
15abcc9-related dilated cardiomyopathy12.4
16actn2-related dilated cardiomyopathy12.4
17eya4-related dilated cardiomyopathy12.4
18ldb3-related dilated cardiomyopathy12.4
19scn5a-associated dilated cardiomyopathy12.4
20tcap-related dilated cardiomyopathy12.4
21actc1-related dilated cardiomyopathy12.3
22ankrd1-related dilated cardiomyopathy12.3
23bag3-related dilated cardiomyopathy12.3
24csrp3-related dilated cardiomyopathy12.3
25des-related dilated cardiomyopathy12.3
26dsg2-related dilated cardiomyopathy12.3
27fktn-related dilated cardiomyopathy12.3
28left ventricular noncompaction 3, with or without dilated cardiomyopathy12.3
29myh6-related dilated cardiomyopathy12.3
30myh7-related dilated cardiomyopathy12.3
31nexn-related dilated cardiomyopathy12.3
32pln-related dilated cardiomyopathy12.3
33psen1-related dilated cardiomyopathy12.3
34psen2-related dilated cardiomyopathy12.3
35rbm20-related dilated cardiomyopathy12.3
36scn5a-related dilated cardiomyopathy12.3
37sgcd-related dilated cardiomyopathy12.3
38taz-related dilated cardiomyopathy12.3
39tmpo-related dilated cardiomyopathy12.3
40tnnt2-related dilated cardiomyopathy12.3
41vcl-related dilated cardiomyopathy12.3
42cryab-related dilated cardiomyopathy12.3
43dilated cardiomyopathy with quadriceps myopathy12.3
44gatad1-related dilated cardiomyopathy12.3
45lama4-related dilated cardiomyopathy12.3
46mybpc3-related dilated cardiomyopathy12.3
47tnnc1-related dilated cardiomyopathy12.3
48tnni3-related dilated cardiomyopathy12.3
49tpm1-related dilated cardiomyopathy12.3
50ttn-related dilated cardiomyopathy12.3

Graphical network of the top 20 diseases related to Dilated Cardiomyopathy:



Diseases related to dilated cardiomyopathy

Symptoms for Dilated Cardiomyopathy

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Drugs & Therapeutics for Dilated Cardiomyopathy

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Drugs for Dilated Cardiomyopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 145)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Valsartanapproved, investigationalPhase 4268137862-53-460846
Synonyms:
(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
(S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(s)-2-(n-((2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl)pentanamido)-3-methylbutanoic acid
137862-53-4
AC-4543
AC1L1U1M
AC1Q5QIK
Ambap137862-53-4
Aventis brand of valsartan
BIDD:GT0345
BRD-K45158365-001-02-3
BSPBio_003501
Bio-0796
C081489
C24H29N5O3
CEPA brand of valsartan
CGP 48933
CGP-48933
CHEBI:9927
CHEMBL1069
CID60846
CPD000466318
D00400
DB00177
Diovan
Diovan (TN)
Diovan, Valsartan
Esteve brand of valsartan
HMS1922L21
HMS2051L12
HMS2093K22
HSDB 7519
KBio2_002287
KBio2_004855
KBio2_007423
KBio3_003006
KBioGR_001078
KBioSS_002289
Kalpress
 
L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)
LS-161334
Lacer brand of valsartan
MLS000759423
MLS001424088
Miten
MolPort-002-507-854
MolPort-003-666-608
N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-Pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-valeryl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)valine
Nisis
Nisis||
Novartis brand of valsartan
Provas
S1894_Selleck
SAM001246581
SMR000466318
SPBio_001260
SPECTRUM1505209
Sanol brand of valsartan
Schwarz brand of valsartan
Spectrum2_001120
Spectrum3_001831
Spectrum4_000749
Spectrum5_001582
Spectrum_001796
TL8000869
Tareg
UNII-80M03YXJ7I
Vals
Valsarran
Valsartan
Valsartan (JAN/USAN/INN)
Valsartan [USAN:INN]
valsartan
walsartan
|Tareg
2
DoxazosinapprovedPhase 45474191-85-83157
Synonyms:
1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin
1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[4-(1,4-benzodioxan-2-yl)carpiperazin-1-yl)]-6,7-dimethoxyquinazoline mesylate
2-[4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-1-yl]-6,7-bis(methyloxy)quinazolin-4-amine
2-[4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
2-{4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine
74191-85-8
77883-43-3 (mesylate)
AC-11062
AC1L1FAT
AC1Q470P
AC1Q4EXN
AKOS001681453
BPBio1_000963
BRD-A13188892-066-03-3
BSPBio_000875
C06970
C23H25N5O5
CHEBI:4708
CHEMBL707
CID3157
CPD000097306
Cardura
Cardura XL
Cardura XL (TN)
Cardura-1
Cardura-2
Cardura-4
ChemDiv2_005017
D07874
D9815_SIGMA
DB00590
 
Doxazosin
Doxazosin (INN)
Doxazosin Mesylate
Doxazosin [INN:BAN]
Doxazosin mesilate
Doxazosin mesylate
Doxazosina
Doxazosina [Spanish]
Doxazosine
Doxazosine [French]
Doxazosinum
Doxazosinum [Latin]
HMS1383E01
HMS2090C20
I06-1346
IDI1_003732
L000738
LS-110228
Lopac0_000474
MolPort-001-684-491
NCGC00018158-06
NCGC00089775-02
Normothen
Oprea1_259518
Prestwick0_000858
Prestwick1_000858
Prestwick2_000858
Prestwick3_000858
SAM002589981
SPBio_002796
UK 33274
UK-33274
UNII-NW1291F1W8
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
doxazosin
3
Carvedilolapproved, investigationalPhase 415372956-09-32585
Synonyms:
(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
107741-96-8
72956-09-3
AB1004830
AC-1641
AC1L1E0B
Artist
Artist (TN)
Atlana Pharma brand of carvedilol
BM 14190
BM-14-190
BM-14.190
BM-14190
BRD-A10977446-001-04-8
BRD-A10977446-045-01-1
Bio-0014
C043211
C06875
C2260
C24H26N2O4
CHEBI:3441
CHEMBL723
CID2585
CPD000449280
Carvedilol
Carvedilol (JAN/USAN/INN)
Carvedilol [USAN:INN:BAN:JAN]
Carvedilolum
Carvedilolum [Latin]
Coreg
Coreg (TN)
Coreg CR
Coropres
Coropress
D00255
DB01136
DQ 2466
DQ-2466
Dibloc
 
Dilatrend
EG-P042
Eucardic
GlaxoSmithKline brand of carvedilol
HMS2051N03
HMS2089B09
HMS2093E12
HSDB 7044
I06-0064
I06-1477
KBio2_002145
KBio2_004713
KBio2_007281
KBio3_002323
KBioGR_001252
KBioSS_002145
Kredex
L001243
LS-121875
Lakeside brand of carvedilol
MLS000758299
MLS000759508
MLS001424092
MolPort-003-666-814
NCGC00167832-01
NCGC00167832-02
NCGC00167832-03
Querto
Roche brand of carvedilol
SAM001246736
SAM001247021
SK&F-105517
SKF 105517
SMR000449280
SPBio_001885
STK621453
Spectrum2_001673
Spectrum3_001182
Spectrum4_000636
Spectrum5_001436
Spectrum_001665
TL8005080
UNII-0K47UL67F2
carvedilol
carvedilol, (+-)-isomer
carvedilol, (R)-isomer
carvedilol, (S)-isomer
carvedilol, 14C-labeled
4
Amiodaroneapproved, investigationalPhase 41141951-25-32157
Synonyms:
(2-Butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diidophenyl)methanone
(2-butyl-1-benzofuran-3-yl)(4-{[2-(diethylamino)ethyl]oxy}-3,5-diiodophenyl)methanone
(2-butyl-1-benzofuran-3-yl)-[4-(2-diethylaminoethyloxy)-3,5-diiodophenyl]methanone
(2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
(2-butylbenzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodo-phenyl]-methanone
(2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine
1951-25-3
2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran
2-Butyl-3-(3,5-diiodo-4-(beta-diethylaminoethoxy)benzoyl)benzofuran
2-Butyl-3-(4'-beta-N-diethylaminoethoxy-3',5'-diiodobenzoyl)benzofuran
2-Butyl-3-[3,5-diiodo-4-(2-di
2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone
2-Butyl-3-benzofuranyl p-((2-diethylamino)ethoxy)-m,m-diiodophenyl ketone
2-Butyl-3-benzofuranyl p-[(2-diethylamino)ethoxy]-m,m-diiodophenyl ketone
2-N-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
5-18-02-00353 (Beilstein Handbook Reference)
AB00053422
AC1L1D1R
AC1Q2VCU
ASTA Medica Brand of Amiodarone Hydrochloride
Alphapharm Brand of Amiodarone Hydrochloride
Amidorone
Aminodarone
Amio-Aqueous IV
Amiobeta
Amiodarex
Amiodarona
Amiodarona [INN-Spanish]
Amiodarone
Amiodarone (USAN/INN)
Amiodarone Base
Amiodarone HCL
Amiodarone Hydrochloride
Amiodarone [USAN:BAN:INN]
Amiodarons
Amiodaronum
Amiodaronum [INN-Latin]
Amiohexal
Amjodaronum
Ancar
Aratac
Armstrong Brand of Amiodarone Hydrochloride
Arycor
BIDD:GT0425
BIDD:PXR0146
BPBio1_000372
BRN 1271711
BSPBio_000338
BSPBio_001574
BSPBio_002580
Berenguer Infale Brand of Amiodarone Hydrochloride
Betapharm Brand of Amiodarone Hydrochloride
Bio1_000026
Bio1_000515
Bio1_001004
Bio2_000294
Bio2_000774
Braxan
C06823
C25H29I2NO3
CAS-19774-82-4
CBiol_001740
CHEBI:2663
CHEMBL633
CID2157
Corbionax
Cordarex
Cordarone
Cordarone Intravenous
D000638
D02910
DB01118
DivK1c_000079
EINECS 217-772-1
G Gam Brand of Amiodarone Hydrochloride
 
HMS1791O16
HMS1989O16
HMS2089C07
Hexal Brand of Amiodarone Hydrochloride
IDI1_000079
IDI1_034044
KBio1_000079
KBio2_000294
KBio2_000741
KBio2_002862
KBio2_003309
KBio2_005430
KBio2_005877
KBio3_000587
KBio3_000588
KBio3_001800
KBioGR_000294
KBioGR_001859
KBioSS_000294
KBioSS_000741
Ketone, 2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl
Ketone, 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl (7CI,8CI)
Kordaron
L 3428
L-3428
L001174
L3428
LS-87088
Labaz
Leurquin Brand of Amiodarone Hydrochloride
Lopac-A-8423
Lopac0_000122
MolPort-003-703-670
NCGC00015096-01
NCGC00015096-02
NCGC00015096-03
NCGC00015096-10
NCGC00024242-03
NCGC00024242-04
NCGC00024242-05
NCGC00024242-06
NCI60_041885
NINDS_000079
Nexterone
Ortacrone
Pacerone
Pharma Investi Brand of Amiodarone Hydrochloride
Prestwick0_000409
Prestwick1_000409
Prestwick2_000409
Prestwick3_000409
QTL1_000008
Rytmarone
SKF 33134-A
SKF 33134A
SPBio_001825
SPBio_002277
STK529812
STOCK1S-12240
Sanofi Winthrop Brand of Amiodarone Hydrochloride
Sedacoron
Sedacorone
Spectrum2_001813
Spectrum3_001050
Spectrum4_001190
Spectrum5_001533
Spectrum_000261
Tachydaron
UNII-N3RQ532IUT
UNM000001215003
Wyeth Brand of Amiodarone Hydrochloride
amiodarone
ethylaminoethoxy)benzoyl]benzofuran
nchembio.79-comp9
nchembio732-comp1
on
pms-Amiodarone
5
EnalaprilapprovedPhase 4, Phase 3, Phase 211275847-73-35362032, 40466924
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline
(S)-1-{(S)-2-[1-((S)-ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester
75847-73-3
AC1NTUS5
Analapril
BIDD:GT0751
BPBio1_000340
BSPBio_000308
BSPBio_003035
Bonuten
C06977
CAS-76095-16-4
CHEBI:116847
CHEBI:4784
CHEMBL578
CID5388962
D07892
DivK1c_000408
Enalapril
Enalapril (INN)
Enalapril (TN)
Enalapril Bp
Enalapril Maleate
Enalapril Richet
Enalaprila
Enalaprila [INN-Spanish]
Enalaprilat
Enalaprilum
 
Enalaprilum [INN-Latin]
Gadopril
HMS2090E08
IDI1_000408
KBio1_000408
KBio2_001787
KBio2_004355
KBio2_006923
KBio3_002535
KBioGR_000355
KBioSS_001787
Kinfil
LS-190651
MolPort-002-885-877
N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline
N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl-L-proline
NCGC00016932-01
NCGC00021569-04
NCGC00021569-05
NCGC00021569-06
NINDS_000408
Prestwick3_000314
SPBio_001349
Spectrum2_001455
Spectrum3_001478
Spectrum4_000008
Spectrum5_001107
Spectrum_001307
Vaseretic
Vasotec
Vasotec IV
enalapril
6
Metoprololapproved, investigationalPhase 4, Phase 219337350-58-64171
Synonyms:
(+/-)-Metoprolol
(RS)-Metoprolol
1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol
1-(Isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanol
1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol
1-[(1-methylethyl)amino]-3-({4-[2-(methyloxy)ethyl]phenyl}oxy)propan-2-ol
1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
1-[4-(2-methoxyethyl)phenoxy]-3-propan-2-ylamino-propan-2-ol
3-[4-(2-methoxyethyl)phenoxy]-1-(propan-2-ylamino)propan-2-ol
37350-58-6
51384-51-1
54163-88-1
AB00053499
AC-19022
AC1L1HKM
AstraZeneca Brand of Metaoprolol Tartrate
AstraZeneca Brand of Seloken
BRD-A03623303-045-02-0
Beatrolol
Beloc
Beloc Duriles
Beloc-Duriles
BelocDuriles
Betaloc
Betaloc Astra
Betaloc-Astra
BetalocAstra
Betalok
C07202
CCRIS 4198
CGP 2175
CGP-2175
CGP2175
CHEBI:6904
CHEMBL13
CID4171
D008790
D02358
DB00264
Dl-Metoprolol
Dutoprol
EINECS 253-483-7
EINECS 257-166-4
H 93 26
H 93-26
H 9326
HMS2090B15
 
HSDB 6531
I01-7125
I06-0125
Jsp006606
L000669
LOPRESSIDONE
LS-122450
Leiras Brand of Metoprolol Succinate or Metoprolol Tartrate
Lopresor
Lopresoretic
Lopressor
Lopressor HCT
Meijoprolol
Metohexal
Metoprolol
Metoprolol (USAN/INN)
Metoprolol Succinate
Metoprolol Succinate extended-release
Metoprolol Tartrate
Metoprolol [USAN:INN:BAN]
Metoprolol succinate
Metoprolol tartrate
Metoprololum
Metoprololum [INN-Latin]
Metroprolol
MolPort-005-938-039
NCGC00021148-02
NCGC00021148-03
NCGC00021148-04
Novartis Brand of Metprolol Tartrate
Preblok
Prelis
Presolol
Selo-Zok
Seloken
Seloken AstraZeneca Brand
Selopral
Seroken
Spesicor
Spesikor
TOPROL-XL
Tartrate, Metoprolol
Toprol
Toprol XL
Toprol-XL
UNII-GEB06NHM23
dl-Metoprolol
metoprolol
7
Benazeprilapproved, investigationalPhase 44586541-75-55362124
Synonyms:
2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid
86541-75-5
AC1NSFPL
BIDD:GT0800
BRD-K49807096-003-02-3
BSPBio_003487
Benazepril
Benazepril (INN)
Benazepril HCl
Benazepril Hydrochloride
Benazepril Sandoz
Benazepril Sandoz (TN)
Benazepril [INN:BAN]
Benazeprilum
Benazeprilum [Latin]
Briem
C06843
CGS-14824-A
CHEBI:3011
CHEMBL838
CID5362124
Cibacen
Cibacene
D07499
DB00542
 
Forteekor [veterinary]
Forteekor [veterinary] (TN)
KBio2_002457
KBio2_005025
KBio2_007593
KBio3_002707
KBioGR_000812
KBioSS_002464
LS-27973
Lotensin
NCGC00165740-01
NCGC00165740-02
SPBio_000343
STK627447
Spectrum2_000482
Spectrum3_001674
Spectrum4_000286
Spectrum5_001546
Spectrum_001922
UNII-UDM7Q7QWP8
[(3S)-3-({(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}amino)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
[(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
[(3S)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
benazapril
benazepril
benzazepril
8
AllopurinolapprovedPhase 4, Phase 1, Phase 2129315-30-02094
Synonyms:
1,5-Dihydro-4H-pyrazolo(3,4-D)pyrimidin-4-one
1,5-Dihydro-4H-pyrazolo(3,4-D)pyrimidine-4-one
184856-42-6
1H-Pyrazolo(3,4-D)pyrimidin-4-ol
22767-92-6
315-30-0
39464-14-7
4'-Hydroxypyrazolol(3,4-D)pyrimidine
4-HPP
4-Hydroxy-1H-pyrazolo(3,4-D)pyrimidine
4-Hydroxy-3,4-pyrazolopyrimidine
4-Hydroxypyrazolo(3,4-D)pyrimidine
4-Hydroxypyrazolopyrimidine
4-Hydroxypyrazolyl(3,4-D)pyrimidine
4H-Pyrazolo(3,4-D)pyrimidin-4-one
7HP
A 8003
A0907
A8003_SIGMA
AC-019
AC1L1CWL
AC1Q6FWV
AC1Q6GP7
AKOS000267490
AKOS000269759
AL-100
Adenock
Ailural
Ailurial
Allo-Puren
Allohexal
Allohexan
Alloprin
Allopur
Allopurin
Allopurinol
Allopurinol Sodium
Allopurinol(I)
Allopurinolum
Allopurinolum [INN-Latin]
Allorin
Allozym
Allpargin
Allural
Aloprim
Alopurinol
Alopurinol [INN-Spanish]
Aloral
Alositol
Aluline
Anoprolin
Anzief
Apo-Allopurinol
Apulonga
Apurin
Apurol
Atisuril
B. W. 56-158
BB_SC-5394
BIM-0061756.0001
BSPBio_001798
BW 56-158
BW 56158
BW-56-158
Bio-0799
Bleminol
Bloxanth
C5H4N4O
CCRIS 626
CHEBI:40279
CHEBI:495607
CHEMBL1467
CID2094
CPD-9024
CPD000059083
Caplenal
Capurate
Cellidrin
Cosuric
D000493
DB00437
Dabrosin
Dabroson
DivK1c_000685
Dura Al
EINECS 206-250-9
EN000932
EU-0100102
Embarin
Epidropal
Epuric
Foligan
Geapur
Gichtex
Gotax
HMS1920A15
HMS2091G15
HMS502C07
HPP
 
HSDB 3004
Hamarin
Hexanuret
I03-0052
IDI1_000685
Jenapurinol
Jsp005881
KBio1_000685
KBio2_000386
KBio2_002954
KBio2_005522
KBio3_001298
KBioGR_000550
KBioSS_000386
Ketanrift
Ketobun-A
LS-1180
Ledopur
Lopac-A-8003
Lopac0_000102
Lopurin
Lysuron
MLS000069453
MLS001148183
Milurit
Milurite
Miniplanor
MolPort-000-141-383
MolPort-000-870-337
MolPort-004-758-159
MolPort-004-758-166
MolPort-004-758-167
MolPort-004-758-643
Monarch
NCGC00015094-01
NCGC00015094-03
NCGC00015094-06
NCGC00091134-01
NCGC00091134-02
NCGC00091134-03
NCGC00094580-01
NCGC00094580-02
NCIOpen2_001825
NINDS_000685
NSC 101655
NSC 1390
NSC-1390
NSC101655
NSC1390
Nektrohan
Novopurol
Pan Quimica
Prestwick_511
Progout
Pureduct
Purinol
Quimica, Pan
Remid
Riball
Rimapurinol
Roucol
S1630_Selleck
SAM002554884
SMR000059083
SPBio_000056
SPECTRUM1500108
STK378584
STK711106
Sigapurol
Spectrum2_000098
Spectrum3_000289
Spectrum4_000135
Spectrum5_000768
Spectrum_000026
Suspendol
Takanarumin
Tipuric
UNII-63CZ7GJN5I
Urbol
Uribenz
Uricemil
Uridocid
Uriprim
Uripurinol
Uritas
Urobenyl
Urolit
Urosin
Urtias
Urtias 100
Xanthomax
Xanturat
Xanturic
Zygout
Zyloprim
Zyloprim (tn)
Zyloric
allopurinol
nchembio.92-comp3
nchembio732-comp4
9
VerapamilapprovedPhase 411752-53-92520
Synonyms:
(+-)-Verapamil
(+/-)-VERAPAMIL
(1)-3-(3,4-Dimethoxyphenyl)-6-((5,6-dimethoxyphenethyl)methylamino)hexane-3-carbonitrile
2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-(1-methylethyl) pentanenitrile
2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile
5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile
5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile
52-53-9
56949-77-0
AB00053495
AC-16016
AC1L1DV5
Akilen
Anpec
Apo-Verap
Arpamyl
Arpamyl LP
BPBio1_000268
BRD-A09533288-001-02-7
BRD-A09533288-003-05-6
BSPBio_000242
BSPBio_001513
BSPBio_002358
Berkatens
Bio-0754
Bio1_000425
Bio1_000914
Bio1_001403
Bio2_000233
Bio2_000713
C07188
C27H38N2O4
CCRIS 6749
CHEBI:9948
CHEMBL6966
CID2520
CP-16533-1
CP-165331
Calan
Calan SR
Calan Sr
Calan sr
Calaptin
Calaptin 240 SR
Calcan
Cardiabeltin
Cardiagutt
Cardibeltin
Cardioprotect
Caveril
Civicor
Civicor Retard
Coraver
Cordilox
Cordilox SR
Corpamil
Covera-HS
Covera-Hs
Covera-hs
D-365
D02356
DB00661
Dexverapamil
Dignover
Dilacoran
Dilacoran HTA
DivK1c_000399
Drosteakard
Durasoptin
EINECS 200-145-1
EINECS 260-462-6
Elthon
FT-0080127
Falicard
Finoptin
Flamon
Geangin
HMS1791L15
HMS1989L15
HMS2089H17
Harteze
Hexasoptin
Hexasoptin Retard
Hormitol
I06-0063
IDI1_000399
IDI1_033983
Ikacor
Ikapress
Inselon
Iproveratril
Isoptimo
Isoptin
Isoptin Retard
Isoptin SR
Isoptin sr
Isoptine
Isoptino
Isotopin
Izoptin
Jenapamil
KBio1_000399
KBio2_000233
KBio2_002343
KBio2_002801
KBio2_004911
KBio2_005369
KBio2_007479
KBio3_000465
KBio3_000466
KBio3_002823
KBioGR_000233
 
KBioGR_001372
KBioGR_002343
KBioSS_000233
KBioSS_002346
L001330
LS-174
Lekoptin
Lodixal
Lopac0_001237
Magotiron
Manidon
Manidon Retard
MolPort-000-721-258
NCGC00016083-14
NCGC00024710-04
NCGC00024710-05
NCGC00024710-06
NCGC00024710-07
NCGC00024710-08
NCGC00024710-09
NCI60_020143
NINDS_000399
NSC272366
NU-Verap
Novapamyl LP
Novo-Veramil
Nu-Verap
Ormil
Praecicor
Prestwick0_000141
Prestwick1_000141
Prestwick2_000141
Prestwick3_000141
Quasar
Rapam
Robatelan
SID104171262
SID124881789
SID124881790
SPBio_001820
SPBio_002181
STK538085
Securon
Spectrum2_001740
Spectrum4_000906
Spectrum5_001786
Tarka
UNII-CJ0O37KU29
Univer
Univex
VERAPAMIL
Vasolan
Vasomil
Vasopten
Vera-Sanorania
Verabeta
Veracaps SR
Veracim
Veracor
Verahexal
Veraloc
Veramex
Veramil
Verapamil
Verapamil (USAN/INN)
Verapamil AL
Verapamil Acis
Verapamil Atid
Verapamil Basics
Verapamil Ebewe
Verapamil HCl
Verapamil Henning
Verapamil Hydrochloride
Verapamil Injection
Verapamil MSD
Verapamil NM
Verapamil NM Pharma
Verapamil Nordic
Verapamil PB
Verapamil Riker
Verapamil SR
Verapamil Verla
Verapamil [USAN:BAN:INN]
Verapamil [USAN:INN:BAN]
Verapamil [Usan:Ban:Inn]
Verapamil-AbZ
Verapamilo
Verapamilo [INN-Spanish]
Verapamilum
Verapamilum [INN-Latin]
Verapin
Verapress 240 SR
Veraptin
Verasal
Verasifar
Veratensin
Verdilac
Verelan
Verelan PM
Verelan Pm
Verelan SR
Verexamil
Veroptinstada
Verpamil
Vetrimil
Vortac
Vérapamil
alpha-((N-Methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile
alpha-(3-((2-(3,4-Dimethoxyphenyl)ethyl)-methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile
alpha-Isopropyl-alpha-((N-methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile
cMAP_000023
delta-365
nchembio.368-comp2
nchembio.79-comp5
10
AmlodipineapprovedPhase 444988150-42-92162
Synonyms:
()-Amlodipine
(RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)
3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxy)methyl)-4-(2-chlorphenyl)-1,4-dihydro-6-methyl-3,5-pyridindicarboxylat
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(O-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (.+/-.)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
88150-42-9
88150-47-4 (maleate (1:1))
AC-4535
AC1L1D26
AC1Q32ZS
AMLODIPINE BASE
AMVAZ
Ambap88150-42-9
Amlocard
Amlodipine
Amlodipine (INN)
Amlodipine Benzenesulfonate
Amlodipine Besilate
Amlodipine Besylate
Amlodipine Free Base
Amlodipine Maleate
Amlodipine [INN:BAN]
Amlodipine besilate
Amlodipine besylate
Amlodipine free base
Amlodipino
Amlodipino [Spanish]
Amlodipinum
Amlodipinum [Latin]
Amlodis
Amlopres
Amlor
 
Amvaz
BIDD:GT0810
BRD-A22032524-074-02-4
BRD-A22032524-074-03-2
BSPBio_002727
C06825
CHEBI:2668
CHEMBL1491
CID2162
CPD000469198
Coroval
D07450
DB00381
HMS2052N03
HMS2089H07
I14-0798
Intervask
Istin
KBio3_001947
KBioGR_001643
LS-131183
Lipinox
Lotrel
MLS001401409
MolPort-001-792-963
NCGC00165957-01
NCGC00165957-02
NCGC00165957-03
Norvasc
Norvasc (TN)
Pelmec
R,S)-Amlodipine
Racemic Amlodipine
SAM001246705
SMR000469198
SPBio_000351
Spectrum2_000486
Spectrum3_001004
Spectrum4_001132
Spectrum5_001550
UK-4834011
UNII-1J444QC288
amlodipine
11
HydrochlorothiazideapprovedPhase 438758-93-53639
Synonyms:
125727-50-6
3,4-Dihydro-6-chloro-7-sulfamyl-1,2, 4-benzothi
3,4-Dihydrochlorothiazide
58-93-5
6-Chloro-7-sulfamoyl-3, 4-dihy
8049-49-8
AB00052012
AC-11072
AC1L1GDT
AC1Q55FM
AF-614/30832002
AKOS000121373
ARONIS24316
Acesistem
Acuilix
Acuretic
Aldactazide
Aldactazide 25/25
Aldazida
Aldectazide 50/50
Aldoril
Ambap58-93-5
Apo-Hydro
Apresazide
Aquarills
Aquarius
Aquazide H
Aquazide-H
BAS 00371709
BIDD:GT0153
BPBio1_000019
BRD-K13078532-001-05-2
BRN 0625101
BSPBio_000017
BSPBio_002132
Bio-0714
Bremil
Briazide
C7H8ClN3O4S2
CAS-58-93-5
CCRIS 2082
CHEMBL435
CID3639
CPD000035778
Caplaril
Capozide
Carozide
Catiazida
Chlorizide
Chlorosulthiadil
Chlorothiazide
Chlorsulfonamidodihydrobenzothiadiazine dioxide
Chlorzide
Chlothia
Cidrex
Clorana
Component of Butizide Prestabs
Concor Plus
Condiuren
D00340
D006852
DB00999
Diaqua
Dichlorosal
Dichlorotride
Dichlothiazide
Dichlotiazid
Dichlotride
Diclotride
Dicyclotride
Didral
Dihydran
Dihydrochlorothiazid
Dihydrochlorothiazide
Dihydrochlorothiazidum
Dihydrochlorurit
Dihydrochlorurite
Dihydroxychlorothiazidum
Direma
Disalunil
Disothiazid
Diu 25 Vigt
Diu-Melusin
Diu-melusin
Diuril
Diurogen
DivK1c_000289
Dixidrasi
Drenol
Dyazide
EINECS 200-403-3
EU-0100614
Esidrex
Esidrix
Esidrix (TN)
Esimil
Esoidrina
FT-0082750
Fluvin
H 4759
H1274
H2910_SIAL
H4759_SIAL
HCT
HCT-Isis
HCTZ
HCZ
HMS1568A19
HMS1920D19
HMS2091L05
HMS500O11
HMS553N04
HSDB 3096
Hidril
Hidro-Niagrin
Hidrochlortiazid
Hidroclorotiazida
Hidroclorotiazida [INN-Spanish]
Hidroronol
Hidrosaluretil
Hidrotiazida
Hyclosid
Hydrex-semi
Hydril
Hydro Par
Hydro-Aquil
Hydro-D
Hydro-Diuril
Hydro-Saluric
Hydro-T
Hydro-chlor
HydroDIURIL
Hydrochlorat
Hydrochloro Thiazide
Hydrochlorot
Hydrochlorothiazid
Hydrochlorothiazide
Hydrochlorothiazide (JP15/USP/INN)
Hydrochlorothiazide Intensol
Hydrochlorothiazide [INN:BAN:JAN]
 
Hydrochlorothiazidum
Hydrochlorothiazidum [INN-Latin]
Hydrochlorthiazide
Hydrochlorthiazidum
Hydrocot
Hydrodiuretic
Hydrodiuril
Hydropres
Hydrosaluric
Hydrothide
Hydrozide
Hydrozide Injection, Veterinary
Hypothiazid
Hypothiazide
Hytrid
Hyzaar
I09-0531
IDI1_000289
Idroclorotiazide
Idroclorotiazide [DCIT]
Idrotiazide
Inderide
Inderide 80/25
Indroclor
Ivaugan
Jen-Diril
KBio1_000289
KBio2_001357
KBio2_003925
KBio2_006493
KBio3_001352
KBioGR_000351
KBioSS_001357
LS-243
Lopac-H-4759
Lopac0_000614
Lopressor HCT
Lotensin HCT
Lotensin Hct
MLS000069619
Manuril
Maschitt
Maxzide
Maybridge Compound 10
Maybridge1_004336
Mazide 25 mg
Medozide
Megadiuril
Microzide
Microzide (TN)
Mictrin
Mikorten
Modurcen
Moduretic
MolPort-000-144-465
NCGC00015508-01
NCGC00015508-02
NCGC00015508-03
NCGC00015508-07
NCGC00015508-12
NCGC00021906-03
NCGC00021906-04
NCGC00021906-05
NCGC00021906-06
NCGC00021906-07
NCGC00021906-08
NCI-C55925
NCI60_004317
NINDS_000289
NSC 53477
NSC53477
Natrinax
Nefrix
Nefrol
Neo-Codema
Neo-Flumen
Neo-Minzil
Neo-codema
Neoflumen
Newtolide
Novodiurex
Oprea1_357174
Oretic
Pantemon
Panurin
Prestwick0_000009
Prestwick1_000009
Prestwick2_000009
Prestwick3_000009
Prestwick_263
Prinzide
Raunova Plus
Ro-Hydrazide
Ro-hydrazide
Roxane
S1708_Selleck
SAM002554901
SMR000035778
SPBio_001259
SPBio_001938
SPECTRUM1500335
STK315354
Saldiuril
Sectrazide
Selozide
Ser-Ap-Es
Servithiazid
Spectrum2_001040
Spectrum3_000456
Spectrum4_000006
Spectrum5_000824
Spectrum_000877
Spironazide
Su 5879
Tandiur
Thiaretic
Thiuretic
Thlaretic
Timolide
UNII-0J48LPH2TH
Unazid
Unipres
Urodiazin
Urozide
Vaseretic
Vetidrex
WLN: T66 BSWM EM DHJ HG ISZW
ZINC00896569
Ziac
Zide
adiazine-1,1-dioxide
component of Aldactazide
component of Aldoril
component of Caplaril
component of Cyclex
component of Dyazide
component of Esimil
diclot ride
dro-2H-1,2,4-benzothiadiazine 1,1-dioxide
hydrochlorothiazide
panurin dichloride
12
SpironolactoneapprovedPhase 41591952-01-7, 52-01-75833
Synonyms:
4-18-00-01601 (Beilstein Handbook Reference)
4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate
496916-40-6
52-01-7
7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone
7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
AB00513806
AC-4214
AC1L1L8Q
Abbolactone
Acelat
Aldace
Aldactazide
Aldactide
Aldactone
Aldactone (TN)
Aldactone A
Alderon
Aldopur
Almatol
Alphapharm Brand of Spironolactone
Alpharma Brand of Spironolactone
Alter Brand of Spironolactone
Altex
Aquareduct
Ashbourne Brand of Spironolactone
Azupharma Brand of Spironolactone
BIDD:PXR0071
BPBio1_000194
BRD-K90027355-001-03-4
BRN 0057767
BSPBio_000176
C07310
C24H32O4S
CHEBI:428201
CHEBI:45692
CHEBI:9241
CHEMBL1393
CID5833
CPD000471892
Cardel Brand of Spironolactone
D00443
D013148
DB00421
Deverol
Dexo Brand of Spironolactone
Diatensec
Dira
Duraspiron
EINECS 200-133-6
Espironolactona
Espironolactona Alter
Espironolactona Mundogen
Espironolactona [INN-Spanish]
Euteberol
Flumach
Frumikal
Generosan Brand of Spironolactone
HMS1568I18
HMS2090N21
HSDB 3184
Hormosan Brand of Spironolactone
I06-1970
Jenapharm Brand of Spironolactone
Jenaspiron
LS-118614
LT00772287
Lacalmin
Lacdene
Laractone
MLS001074672
MLS001333253
MLS001333254
MLS002153245
MLS002207058
Mayoly-Spindler Brand of Spironolactone
Melarcon
Merck dura Brand of Spironolactone
Mundogen Brand of Spironolactone
NCGC00164397-01
 
NCGC00164397-02
NSC 150399
NSC150399
Nefurofan
Novo Spiroton
Novo-Spiroton
NovoSpiroton
Novopharm Brand of Spironolactone
Osyrol
Pfizer Brand of Spironolactone
Pharmafrid Brand of Spironolactone
Practon
Prestwick0_000128
Prestwick1_000128
Prestwick2_000128
Prestwick3_000128
Roche Brand of Spironolactone
S0260
S3378_SIGMA
SAM002264648
SC 9420
SC-9420
SC9420
SMR000471892
SNL
SPBio_002115
Sagisal
Searle Brand of Spironolactone
Sincomen
Spiractin
Spiresis
Spiretic
Spiridon
Spiro L.U.T.
Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan)
Spiro-Tablinen
Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan]
Spirobeta
Spiroctan
Spiroctanie
Spiroderm
Spirogamma
Spirolactone
Spirolakton
Spirolang
Spirolone
Spirone
Spirono Isis
Spirono-Isis
Spironocompren
Spironolactone
Spironolactone (JP15/USP/INN)
Spironolactone A
Spironolactone [BAN:INN:JAN]
Spironolactone [INN:BAN:JAN]
Spironolactonum
Spironolactonum [INN-Latin]
Spironolattone
Spironolattone [DCIT]
Spironone
Spirospare
Sprioderm
Supra-puren
Suracton
UNII-27O7W4T232
Uractone
Urusonin
Veroshpiron
Verospiron
Verospirone
Verospirone Opianin
WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ
Worwag Brand of Spironolactone
Xenalon
ZINC03861599
betapharm Brand of Spironolactone
ct Arzneimittel Brand of Spironolactone
ct-Arzneimittel Brand of Spironolactone
spiro von ct
spironolactone
spironolattone
von ct, spiro
13
Nitric OxideapprovedPhase 456410102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
Inomax
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
14
Uric Acidexperimental, investigationalPhase 412069-93-21175
Synonyms:
1H-Purine-2,6,8-triol
2,6,8-Trihydroxypurine
2,6,8-Trioxopurine
2,6,8-Trioxypurine
 
7,9-dihydro-1H-purine-2,6,8(3H)-trione
Lithate
Lithic acid
Purine-2,6,8(1H,3H,9H)-trione
Urate
Uric acid
15Anticholesteremic AgentsPhase 4, Phase 31732
16AntimetabolitesPhase 4, Phase 3, Phase 1, Phase 29454
17Antirheumatic AgentsPhase 4, Phase 1, Phase 28496
18Protective AgentsPhase 4, Phase 1, Phase 25651
19Hydroxymethylglutaryl-CoA Reductase InhibitorsPhase 4, Phase 31804
20AntibodiesPhase 4, Phase 2, Phase 14477
21Natriuretic AgentsPhase 4, Phase 31403
22Hormone AntagonistsPhase 4, Phase 310002
23HormonesPhase 4, Phase 311748
24Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 39988
25Insulin, Globin ZincPhase 44278
26insulinPhase 44278
27Natriuretic Peptide, BrainPhase 4176
28ImmunoglobulinsPhase 4, Phase 2, Phase 14477
29calcium channel blockersPhase 4, Phase 21743
30Calcium, DietaryPhase 4, Phase 3, Phase 24678
31Hypolipidemic AgentsPhase 4, Phase 32228
32AntioxidantsPhase 4, Phase 1, Phase 22442
33
EnalaprilatPhase 4, Phase 3, Phase 211276420-72-96917719
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid dihydrate
1-((2S)-2-{[(1S)-1-CARBOXY-3-PHENYLPROPYL]AMINO}PROPANOYL)-L-PROLINE
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate
76420-72-9
AC1NUWEA
AC1OCEK7
BIDD:GT0752
C11720
C18H24N2O5.2H2O
CHEBI:116759
CHEBI:42302
CHEBI:4786
CHEBI:59877
CHEMBL1200697
CHEMBL577
CID5462501
CID6917719
CPD000466359
D03769
EAL
ENALAPRILAT INHIBITOR
Enalapril acid
Enalapril diacid
 
Enalaprilat
Enalaprilat (USP)
Enalaprilat anhydrous
Enalaprilate
Enalaprilatum
Enalaprilic acid
Enalprilate hydrate
HMS2051H16
HMS2089P04
LS-118903
LS-187219
MK-422
MLS000759476
MLS001424138
MolPort-005-943-792
N-[(1S)-1-Carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline--water (1/2)
NCGC00164593-01
S1657_Selleck
SAM001246684
SBB065733
SMR000466359
Vasotec I.V.
enalprilat hydrate
34Adrenergic beta-1 Receptor AntagonistsPhase 4, Phase 3292
35
Angiotensin IIPhase 4, Phase 3103368521-88-0, 11128-99-7172198, 65143
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
36Angiotensin II Type 1 Receptor BlockersPhase 4, Phase 3949
37Angiotensin Receptor AntagonistsPhase 4, Phase 31039
38Adrenergic AntagonistsPhase 4, Phase 3, Phase 21253
39Adrenergic AgentsPhase 4, Phase 3, Phase 24204
40MicronutrientsPhase 43901
41Trace ElementsPhase 43900
42UbiquinonePhase 492
43VitaminsPhase 43857
44Angiotensin-Converting Enzyme InhibitorsPhase 4, Phase 3, Phase 2634
45Adrenergic beta-AntagonistsPhase 4, Phase 3, Phase 2979
46Protease InhibitorsPhase 4, Phase 3, Phase 24558
47Peripheral Nervous System AgentsPhase 4, Phase 318510
48AngiotensinogenPhase 4, Phase 31032
49Adrenergic alpha-AntagonistsPhase 4586
50Vasodilator AgentsPhase 4, Phase 3, Phase 22926

Interventional clinical trials:

(show top 50)    (show all 174)
idNameStatusNCT IDPhase
1Coenzyme Q10 Supplementation in Children With Idiopathic Dilated CardiomyopathyCompletedNCT02115581Phase 4
2Supramaximal Titrated Inhibition of RAAS in Dilated CardiomyopathyCompletedNCT01917149Phase 4
3Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human HeartCompletedNCT01798992Phase 4
4Spanish Atrial Fibrillation And Resynchronization StudyCompletedNCT01181414Phase 4
5A Randomized Trial of Carvedilol in Chronic Chagas CardiomyopathyCompletedNCT01557140Phase 4
6ACC - Atrial Contribution to CRTCompletedNCT00180323Phase 4
7Effects of Allopurinol on Diastolic Function in Chronic Heart Failure PatientsCompletedNCT00477789Phase 4
8Effects of Early Statin Treatment After Acute Myocardial Infarction (AMI) in Japanese PatientsCompletedNCT00128024Phase 4
9Sleep Apnea-hypopnea Syndrome (SAHS) and Ventricular ArrhythmiasCompletedNCT00765713Phase 4
10Multicenter Study of Immunoadsorption in Dilated CardiomyopathyRecruitingNCT00558584Phase 4
11Study of Qiliqiangxin Capsule to Treat Dilated CardiomyopathyRecruitingNCT01293903Phase 4
12Therapy With Verapamil or Carvedilol in Chronic Heart FailureRecruitingNCT00374465Phase 4
13(MitraClip in Non-Responders to Cardiac Resynchronization Therapy)RecruitingNCT02592889Phase 4
14Regression of Fatty Heart by Valsartan TherapyRecruitingNCT00745953Phase 4
15Danish ICD Study in Patients With Dilated CardiomyopathyActive, not recruitingNCT00542945Phase 4
16Effect of Aldosterone on Energy Starvation in Heart FailureActive, not recruitingNCT00574119Phase 4
17Efficacy of Implantable Cardioverter Defibrillator in Patients With Non-ischemic Systolic Heart Failure on MortalityActive, not recruitingNCT00541268Phase 4
18Identification of Carnitine-Responsive CardiomyopathyNot yet recruitingNCT01904396Phase 4
19NORDIC: Nitric Oxide-Derived Oxidants and Regional Endothelial and Diastolic Dysfunction in Dilated CardiomyopathyTerminatedNCT00293137Phase 4
20Cardiac Sarcoidosis Response To Steroids TrialWithdrawnNCT01210677Phase 4
21Autologous Transplantation of Bone Marrow Mononuclear Stem-Cells for Dilated CardiomyopathyCompletedNCT00743639Phase 2, Phase 3
22PUFAs and Left Ventricular Function in Heart FailureCompletedNCT01223703Phase 3
23The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow DistributionCompletedNCT00741156Phase 3
24Effect of Rosuvastatin on Left Ventricular RemodelingCompletedNCT00505154Phase 3
25Randomized Trial of Interventions to Improve Warfarin AdherenceCompletedNCT00904982Phase 3
26Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan SyndromeCompletedNCT00723801Phase 3
27Cell Therapy In Dilated CardiomyopathyRecruitingNCT00333827Phase 3
28Infusion Intracoronary of Mononuclear Autologous Adult no Expanded Stem Cells of Bone Marrow on Functional Recovery in Patients With Idiopathic Dilated Cardiomyopathy and Heart Failure.RecruitingNCT02033278Phase 2, Phase 3
29Repetitive Intramyocardial CD34+ Cell Therapy in Dilated Cardiomyopathy (REMEDIUM)RecruitingNCT02248532Phase 2, Phase 3
30PHOspholamban RElated CArdiomyopathy STudy - InterventionRecruitingNCT01857856Phase 3
31CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY)RecruitingNCT02369978Phase 2, Phase 3
32A Randomized, Controlled Study to Evaluate Algisyl-LVR™ as a Method of Left Ventricular Augmentation for Heart FailureActive, not recruitingNCT01311791Phase 2, Phase 3
33Orodispersible Minitablets of Enalapril in Children With Heart Failure Due to Dilated CardiomyopathyNot yet recruitingNCT02652728Phase 2, Phase 3
34Follow-up Safety Trial in Children With Chronic Heart Failure Therapy Receiving Orodispersible Minitablets of EnalaprilNot yet recruitingNCT02654678Phase 2, Phase 3
35PREclinical Mutation CARriers From Families With DIlated Cardiomyopathy and ACE InhibitorsTerminatedNCT01583114Phase 3
36Mental Stress Reduction in Defibrillator PatientsTerminatedNCT00624520Phase 3
37Cell Therapy in Chagas CardiomyopathyTerminatedNCT00349271Phase 3
38Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart FailureTerminatedNCT00608140Phase 3
39Use of Ixmyelocel-T (Formerly Cardiac Repair Cell [CRC] Treatment) in Patients With Heart Failure Due to Dilated Cardiomyopathy (IMPACT-DCM)CompletedNCT00765518Phase 2
40Use of Ixmyelocel-T (Formerly Catheter-based Cardiac Repair Cell [CRC]) Treatment in Patients With Heart Failure Due to Dilated CardiomyopathyCompletedNCT01020968Phase 2
41Safety and Efficacy Study of Intramyocardial Stem Cell Therapy in Patients With Dilated CardiomyopathyCompletedNCT01350310Phase 2
42Safety and Efficacy Study of Stem Cell Transplantation to Treat Dilated CardiomyopathyCompletedNCT00629018Phase 2
43Bone Marrow Derived Adult Stem Cells for Dilated CardiomyopathyCompletedNCT01302171Phase 2
44Intracoronary Infusion of Autologous Bone Marrow Cells for Treatment of Idiopathic Dilated CardiomyopathyCompletedNCT00629096Phase 2
45Autologous Transplantation of Bone Marrow Mononuclear Stem-Cells by Mini-ThoracotomyCompletedNCT00615394Phase 1, Phase 2
46Safety and Feasibility of Algisyl-LVR™ as a Method of Left Ventricular Restoration in Patients With DCM Undergoing Open-heart SurgeryCompletedNCT00847964Phase 2
47Progenitor Cell Therapy in Dilative CardiomyopathyCompletedNCT00284713Phase 1, Phase 2
48PET Scan to Determine Areas of Blood Flow and Activity in the Hearts of Patients With Heart Disease Taking Beta-BlockersCompletedNCT00001402Phase 2
49Pilot Study of COR-1 in Heart FailureCompletedNCT01391507Phase 2
50Impact of Intraventricular Electrical Activation in Resynchronization TherapyCompletedNCT01270646Phase 2

Search NIH Clinical Center for Dilated Cardiomyopathy

Inferred drug relations via UMLS65/NDF-RT43:

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Dilated Cardiomyopathy cell therapies at LifeMap Discovery.

Genetic Tests for Dilated Cardiomyopathy

About this section

Genetic tests related to Dilated Cardiomyopathy:

id Genetic test Affiliating Genes
1 Dilated Cardiomyopathy22 VCL

Anatomical Context for Dilated Cardiomyopathy

About this section

MalaCards organs/tissues related to Dilated Cardiomyopathy:

33
Heart, Bone, Liver, Endothelial, Lung, Breast, Bone marrow

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Dilated Cardiomyopathy:
id TissueAnatomical CompartmentCell Relevance
1 HeartMyocardiumCardiomyocytes Affected by disease
2 HeartLeft VentricleCardiomyocytes Potential therapeutic candidate, affected by disease
3 BloodCord BloodMesenchymal Stem Cells Potential therapeutic candidate
4 Umbilical CordWharton's JellyMesenchymal Stem Cells Potential therapeutic candidate

Animal Models for Dilated Cardiomyopathy or affiliated genes

About this section

MGI Mouse Phenotypes related to Dilated Cardiomyopathy:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.6ACTC1, ADRB1, CSRP3, DES, DMD, EYA4
2MP:00107688.4ACTC1, ADRB1, CSRP3, DES, DMD, EYA4
3MP:00053788.4ACTC1, ADRB1, CSRP3, DMD, EYA4, LDB3
4MP:00053698.2ACTC1, ADRB1, CSRP3, DES, DMD, EMD
5MP:00053858.2ACTC1, ADRB1, CSRP3, DES, DMD, EMD

Publications for Dilated Cardiomyopathy

About this section

Articles related to Dilated Cardiomyopathy:

(show top 50)    (show all 1441)
idTitleAuthorsYear
1
Identification of a Large SLC25A13 Deletion via Sophisticated Molecular Analyses Using Peripheral Blood Lymphocytes in an Infant with Neonatal Intrahepatic Cholestasis Caused by Citrin Deficiency (NICCD): A Clinical and Molecular Study. (27127784)
2016
2
Urinary neutrophil gelatinase-associated lipocalin as an early predictor of disease severity and mortality in acute pancreatitis. (25426620)
2015
3
miR-29b suppresses proliferation, migration, and invasion of tongue squamous cell carcinoma through PTEN-AKT signaling pathway by targeting Sp1. (25127200)
2014
4
What information do Dutch midwives give clients about toxoplasmosis, listeriosis and cytomegalovirus prevention? An exploratory study of videotaped consultations. (24820638)
2014
5
Significant simultaneous changes in serum CA19-9 and CA125 due to prolonged torsion of mature cystic teratoma of the ovary. (25416055)
2014
6
Scrotal pop off in a congenital anterior urethral diverticulum. (24928476)
2014
7
Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice. (24979782)
2014
8
First case series of emerging Rickettsial neonatal sepsis identified by polymerase chain reaction-based deoxyribonucleic acid sequencing. (24064639)
2013
9
Candidates for Limited Lateral Neck Dissection among Patients with Metastatic Papillary Thyroid Carcinoma. (24337241)
2013
10
Fasting blood sugar and serum triglyceride as the risk factors of colorectal adenoma in korean population receiving screening colonoscopy. (23429421)
2013
11
Neurally adjusted ventilatory assist (NAVA) mode as an adjunct diagnostic tool in congenital central hypoventilation syndrome. (23374524)
2013
12
Transmitted HIV Type 1 drug resistance and Non-B subtypes prevalence among seroconverters and newly diagnosed patients from 1992 to 2005 in Italy. (20055587)
2010
13
The effect of surface microtopography of poly(dimethylsiloxane) on protein adsorption, platelet and cell adhesion. (19303747)
2009
14
The accessory subunit of mitochondrial DNA polymerase gamma determines the DNA content of mitochondrial nucleoids in human cultured cells. (19625489)
2009
15
Adipogenic human adenovirus Ad-36 induces commitment, differentiation, and lipid accumulation in human adipose-derived stem cells. (18203674)
2008
16
Two-year follow-up of splenic radiofrequency ablation in patients with cirrhotic hypersplenism: does increased hepatic arterial flow induce liver regeneration? (18374048)
2008
17
Apoptosis of murine lupus T cells induced by the selective cyclooxygenase-2 inhibitor celecoxib: molecular mechanisms and therapeutic potential. (17761345)
2007
18
Antarctic fish mitochondrial genomes lack ND6 gene. (17955154)
2007
19
Recommendations for the treatment of scabies infestations in Israel. (16599057)
2006
20
P-glycoprotein restricts access of cortisol and dexamethasone to the glucocorticoid receptor in placental BeWo cells. (16873536)
2006
21
A study on dyslipidaemia in subclinical hypothyroidism. (17444061)
2006
22
Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer. (16551709)
2006
23
Gene therapy of the brain in the dog model of Hurler's syndrome. (16718701)
2006
24
Role of corticotropin-releasing factor pathways in stress-related alterations of colonic motor function and viscerosensibility in female rodents. (16290887)
2005
25
Effect of cyclosporin A eye drop on keratoconjunctivitis sicca and its mechanism. (16696343)
2005
26
Utilization of bone histomorphometry in renal osteodystrophy: demonstration of a new approach using data from a prospective study of lanthanum carbonate. (15730056)
2005
27
Hypoxia-inducible factor-1alpha is associated with risk of aggressive behavior and tumor angiogenesis in gastrointestinal stromal tumor. (15845570)
2005
28
The effect of childhood conduct disorder and cognitive functioning on adolescent substance use. (15337863)
2004
29
Mutations of the anti-mullerian hormone gene in patients with persistent mullerian duct syndrome: biosynthesis, secretion, and processing of the abnormal proteins and analysis using a three-dimensional model. (14673134)
2004
30
Autocrine transforming growth factor alpha regulates cell adhesion by multiple signaling via specific phosphorylation sites of p70S6 kinase in colon cancer cells. (15304500)
2004
31
Transformation between Kaposiform hemangioendothelioma and tufted angioma. (12771476)
2003
32
Notch1 competes with the amyloid precursor protein for gamma-secretase and down-regulates presenilin-1 gene expression. (12960155)
2003
33
Snail is required for Delta endocytosis and Notch-dependent activation of single-minded expression. (12632175)
2003
34
Update on juvenile dermatomyositis: new advances in understanding its etiopathogenesis. (12960487)
2003
35
Development of hip dysplasia in hereditary multiple exostosis. (11242251)
2001
36
A phase II trial of recombinant interferon alpha-2b and cisplatin in metastatic melanoma. (11093371)
2000
37
Genetic landmarks through philately--hereditary breast cancer. (10450857)
1999
38
Lymphedema-distichiasis syndrome: report of a case and review. (10086462)
1999
39
MR of right aortic arch. (8657471)
1996
40
Effects of recombinant dimeric TNF receptor on human inflammatory responses following intravenous endotoxin administration. (7594512)
1995
41
gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory. (7516405)
1994
42
Expression of glucose transporters in head-and-neck tumors. (8314336)
1994
43
Intestinal perforation due to Mycobacterium tuberculosis in HIV-infected individuals: report of two cases. (8470647)
1993
44
X-Linked Agammaglobulinemia (20301626)
1993
45
Spirochetes in early lesions of necrotizing ulcerative gingivitis experimentally induced in beagles. (2087354)
1990
46
Electrophysiologic studies in birdshot chorioretinopathy. (3177561)
1988
47
Clear-cell adenocarcinoma of the female urethra. (3856984)
1985
48
Survival after portal venous gas due to mesenteric vascular occlusion. (6831162)
1983
49
Rhinosporidiosis with a record of 255 cases. (14441917)
1960
50

Variations for Dilated Cardiomyopathy

About this section

Clinvar genetic disease variations for Dilated Cardiomyopathy:

5 (show all 17)
id Gene Variation Type Significance SNP ID Assembly Location
1TNNT2NM_000364.3(TNNT2): c.451C> T (p.Arg151Trp)single nucleotide variantLikely pathogenic, Pathogenicrs74315379GRCh37Chr 1, 201333464: 201333464
2NM_002667.4(PLN): c.116T> G (p.Leu39Ter)single nucleotide variantLikely pathogenic, Pathogenicrs111033560GRCh37Chr 6, 118880200: 118880200
3MYH6NM_002471.3(MYH6): c.3010G> T (p.Ala1004Ser)single nucleotide variantLikely pathogenic, Pathogenicrs143978652GRCh37Chr 14, 23862646: 23862646
4LMNANM_170707.3(LMNA): c.1930C> T (p.Arg644Cys)single nucleotide variantLikely pathogenic, Pathogenicrs142000963GRCh37Chr 1, 156108510: 156108510
5MYBPC3NM_000256.3(MYBPC3): c.2311G> A (p.Val771Met)single nucleotide variantPathogenicrs371488302GRCh37Chr 11, 47359343: 47359343
6MYBPC3NM_000256.3(MYBPC3): c.961G> A (p.Val321Met)single nucleotide variantPathogenicrs200119454GRCh37Chr 11, 47367887: 47367887
7ACTN2NM_001103.3(ACTN2): c.26A> G (p.Gln9Arg)single nucleotide variantLikely pathogenic, Pathogenicrs121434525GRCh37Chr 1, 236849999: 236849999
8NM_001943.3(DSG2): c.3059_3062delAGAG (p.Glu1020Alafs)deletionPathogenicrs794728096GRCh37Chr 18, 29126408: 29126411
9RBM20NM_001134363.2(RBM20): c.1906C> A (p.Arg636Ser)single nucleotide variantLikely pathogenic, Pathogenicrs267607002GRCh37Chr 10, 112572061: 112572061
10RBM20NM_001134363.2(RBM20): c.1907G> A (p.Arg636His)single nucleotide variantPathogenicrs267607004GRCh37Chr 10, 112572062: 112572062
11MYPNNM_032578.3(MYPN): c.3335C> T (p.Pro1112Leu)single nucleotide variantLikely pathogenic, Pathogenicrs71534278GRCh37Chr 10, 69959174: 69959174
12MYPNNM_032578.3(MYPN): c.59A> G (p.Tyr20Cys)single nucleotide variantLikely pathogenic, Pathogenicrs140148105GRCh37Chr 10, 69881254: 69881254
13NEXNNM_144573.3(NEXN): c.1955A> G (p.Tyr652Cys)single nucleotide variantLikely pathogenic, Pathogenicrs137853197GRCh37Chr 1, 78408441: 78408441
14NM_001267550.2(TTN): c.57331C> T (p.Arg19111Ter)single nucleotide variantLikely pathogenic, Pathogenicrs72646831GRCh37Chr 2, 179462478: 179462478
15NM_001256850.1(TTN): c.66679C> T (p.Arg22227Ter)single nucleotide variantLikely pathogenic, Pathogenicrs397517689GRCh37Chr 2, 179439257: 179439257
16LDB3NM_001080116.1(LDB3): c.349G> A (p.Asp117Asn)single nucleotide variantPathogenicrs121908338GRCh37Chr 10, 88446830: 88446830
17SCN5ANM_000335.4(SCN5A): c.2314G> A (p.Asp772Asn)single nucleotide variantPathogenicrs199473157GRCh37Chr 3, 38629013: 38629013

Expression for genes affiliated with Dilated Cardiomyopathy

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Search GEO for disease gene expression data for Dilated Cardiomyopathy.

Pathways for genes affiliated with Dilated Cardiomyopathy

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Pathways related to Dilated Cardiomyopathy according to KEGG:

31
id Name KEGG Source Accession
1Dilated cardiomyopathyhsa05414

Pathways related to Dilated Cardiomyopathy according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
110.1ACTC1, SCN5A, TNNT2
210.0ACTC1, MYH7, RYR2, TNNT2
3
Show member pathways
9.9ACTC1, ADRB1, PLN, RYR2
49.8ADRB1, LMNA, PLN, RYR2, SCN5A
59.7ACTC1, DES, DMD, MYBPC3, TNNT2, TTN
6
Show member pathways
9.5ACTC1, ADRB1, MYH7, PLN, RYR2, SCN5A
7
Show member pathways
9.3DES, DMD, MYBPC3, PLN, RYR2, SCN5A
8
Show member pathways
8.7ACTC1, ADRB1, DES, DMD, EMD, LMNA

GO Terms for genes affiliated with Dilated Cardiomyopathy

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Cellular components related to Dilated Cardiomyopathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1dystrophin-associated glycoprotein complexGO:001601010.7DMD, SGCD
2cellGO:000562310.6RYR2, VCL
3cytoskeletonGO:00058569.9DES, LDB3, SGCD, VCL
4cytosolGO:00058299.6ACTC1, LMNA, MYBPC3, RYR2, TAZ, TNNT2

Biological processes related to Dilated Cardiomyopathy according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1ventricular cardiac muscle cell action potentialGO:008600510.7RYR2, SCN5A
2regulation of cardiac muscle cell contractionGO:008600410.6PLN, SCN5A
3cardiac muscle tissue developmentGO:004873810.6SGCD, TAZ
4cardiac myofibril assemblyGO:005500310.3ACTC1, CSRP3, TTN
5positive regulation of ATPase activityGO:003278110.3MYBPC3, TNNT2
6muscle filament slidingGO:003004910.2ACTC1, MYBPC3, MYH7, TTN
7muscle contractionGO:000693610.1EMD, TAZ, TTN
8skeletal muscle tissue developmentGO:000751910.0CSRP3, DMD, TAZ
9cardiac muscle contractionGO:00600489.5DMD, RYR2, TAZ, TNNT2, TTN

Sources for Dilated Cardiomyopathy

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet