MCID: DPH012
MIFTS: 23

Diphallia

Categories: Rare diseases, Fetal diseases

Aliases & Classifications for Diphallia

Summaries for Diphallia

MalaCards based summary : Diphallia, also known as diphallus, is related to diphallus rachischisis imperforate anus and hypospadias, and has symptoms including bifid scrotum, bifid penis and hypospadias. Affiliated tissues include kidney, colon and heart.

Wikipedia : 72 Diphallia, penile duplication (PD), diphallic terata, or diphallasparatus, is a rare developmental... more...

Related Diseases for Diphallia

Diseases related to Diphallia via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 diphallus rachischisis imperforate anus 11.8
2 hypospadias 9.8
3 imperforate anus 9.8
4 urethritis 9.8
5 urethral stricture 9.8

Graphical network of the top 20 diseases related to Diphallia:



Diseases related to Diphallia

Symptoms & Phenotypes for Diphallia

Human phenotypes related to Diphallia:

56 32 (show all 30)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 bifid scrotum 56 32 hallmark (90%) Very frequent (99-80%) HP:0000048
2 bifid penis 56 32 hallmark (90%) Very frequent (99-80%) HP:0100599
3 hypospadias 56 32 frequent (33%) Frequent (79-30%) HP:0000047
4 anal atresia 56 32 frequent (33%) Frequent (79-30%) HP:0002023
5 distal urethral duplication 56 32 frequent (33%) Frequent (79-30%) HP:0008706
6 ectopic scrotum 56 32 frequent (33%) Frequent (79-30%) HP:0030275
7 penoscrotal transposition 56 32 frequent (33%) Frequent (79-30%) HP:0100600
8 inguinal hernia 56 32 occasional (7.5%) Occasional (29-5%) HP:0000023
9 cryptorchidism 56 32 occasional (7.5%) Occasional (29-5%) HP:0000028
10 epispadias 56 32 occasional (7.5%) Occasional (29-5%) HP:0000039
11 ureteral duplication 56 32 occasional (7.5%) Occasional (29-5%) HP:0000073
12 renal duplication 56 32 occasional (7.5%) Occasional (29-5%) HP:0000075
13 horseshoe kidney 56 32 occasional (7.5%) Occasional (29-5%) HP:0000085
14 bladder exstrophy 56 32 occasional (7.5%) Occasional (29-5%) HP:0002836
15 abnormality of the pubic bone 56 32 occasional (7.5%) Occasional (29-5%) HP:0003172
16 renal malrotation 56 32 occasional (7.5%) Occasional (29-5%) HP:0004712
17 abnormal spermatogenesis 56 32 occasional (7.5%) Occasional (29-5%) HP:0008669
18 cloacal exstrophy 56 32 occasional (7.5%) Occasional (29-5%) HP:0010475
19 scoliosis 56 32 very rare (1%) Very rare (<4-1%) HP:0002650
20 hemivertebrae 56 32 very rare (1%) Very rare (<4-1%) HP:0002937
21 butterfly vertebrae 56 32 very rare (1%) Very rare (<4-1%) HP:0003316
22 rectoperineal fistula 56 32 very rare (1%) Very rare (<4-1%) HP:0004792
23 duplicated colon 56 32 very rare (1%) Very rare (<4-1%) HP:0005223
24 absent thumb 56 32 very rare (1%) Very rare (<4-1%) HP:0009777
25 abnormality of the genitourinary system 56 Very frequent (99-80%)
26 abnormal heart morphology 56 Occasional (29-5%)
27 atria septal defect 56 Occasional (29-5%)
28 abnormality of the gastrointestinal tract 56 Occasional (29-5%)
29 gastrointestinal duplication 56 Occasional (29-5%)
30 atrial septal defect 32 occasional (7.5%) HP:0001631

Drugs & Therapeutics for Diphallia

Search Clinical Trials , NIH Clinical Center for Diphallia

Genetic Tests for Diphallia

Anatomical Context for Diphallia

MalaCards organs/tissues related to Diphallia:

39
Kidney, Colon, Heart, Bone

Publications for Diphallia

Articles related to Diphallia:

(show all 30)
id Title Authors Year
1
Diphallia in a Mixed-Breed Puppy: Case Report. ( 28792795 )
2017
2
Diphallia in the Ancient World: Insights From a Pompeian Fresco (70-79 AD). ( 27562204 )
2016
3
Unusual Variant of Coronal Bladder Duplication Associated with Glans Diphallia: A Case Report and Review of the Literature. ( 26114007 )
2015
4
Prenatal diagnosis of true diphallia and associated anomalies. ( 25004320 )
2014
5
Diphallia with associated anomalies: a case report and literature review. ( 24383036 )
2013
6
A rare case of isolated complete diphallia and review of the literature. ( 23413289 )
2013
7
Isolated diphallia: case report and literature review. ( 19431105 )
2009
8
A case of perineal lipoma with accessory scrotum and pseudo- diphallia. ( 19221954 )
2009
9
Complete diphallia. ( 19230173 )
2008
10
MRI in the diagnosis of diphallia. ( 17909781 )
2007
11
Successful surgical correction of true diphallia, scrotal duplication, and associated hypospadias. ( 17011251 )
2006
12
Complete diphallia, imperforate ani (type 2 atresia ani), and an accessory scrotum in a 5-day-old calf. ( 16921886 )
2006
13
Complete diphallia. ( 15764263 )
2004
14
Complete diphallia associated with features of covered exstrophy. ( 11431797 )
2001
15
Diphallia and the VATER association. ( 10569606 )
1999
16
Complete lower urinary tract duplication with true diphallia presenting as a rare covered exstrophy variant. ( 9112561 )
1997
17
True complete diphallia. ( 7569806 )
1995
18
Diphallia and hindgut duplication. ( 1989030 )
1991
19
Value of sonography in true complete diphallia. ( 2664222 )
1989
20
Diphallia in a mixed-breed dog with multiple anomalies. ( 16726645 )
1989
21
Diphallia associated with malformation of hindgut derivatives. ( 2919482 )
1989
22
A case of diphallia. ( 3727229 )
1986
23
Diphallia with a normal and a blind-ending urethra. ( 446509 )
1979
24
Diphallia. ( 4772820 )
1973
25
Diphallia: report of a case. ( 5047441 )
1972
26
Diphallia in a Holstein bull. ( 5101822 )
1971
27
Diphallia. Report of a case. ( 5471752 )
1970
28
Diphallia: report of a case. ( 5846196 )
1965
29
TOTAL DIPHALLIA: A CASE OF PLASTIC REPAIR. ( 14104422 )
1964
30
Ectopic scrotum and diphallia: report of a case. ( 13791708 )
1960

Variations for Diphallia

Expression for Diphallia

Search GEO for disease gene expression data for Diphallia.

Pathways for Diphallia

GO Terms for Diphallia

Sources for Diphallia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
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33 ICD10
34 ICD10 via Orphanet
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59 PubMed
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65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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