MCID: DPH001
MIFTS: 58

Diphtheria malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Diphtheria

About this section
Sources:
2CDC, 11Disease Ontology, 12diseasecard, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 38MedlinePlus, 39MeSH, 40MESH via Orphanet, 48NIH Rare Diseases, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Diphtheria:

Name: Diphtheria 11 48 54 50 38 2 13 68
Corynebacterium Infections 39 68
 
Diphtheria, Susceptibility to 12
Corynebacterium Infection 11

Characteristics:

Orphanet epidemiological data:

54
diphtheria:
Prevalence: <1/1000000 (Europe); Age of onset: All ages; Age of death: any age

Classifications:



External Ids:

Disease Ontology11 DOID:11405
MeSH39 D003354
Orphanet54 ORPHA1679
ICD10 via Orphanet31 A36.1, A36.2, A36.3 A36.8, A36.0, A36.9, more
SNOMED-CT62 397434007
MESH via Orphanet40 D004165
UMLS via Orphanet69 C0012546
ICD1030 A36, A36.9

Summaries for Diphtheria

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MedlinePlus:38 Diphtheria is a serious bacterial infection. you can catch it from a person who has the infection and coughs or sneezes. you can also get infected by coming in contact with an object, such as a toy, that has bacteria on it. diphtheria usually affects the nose and throat. symptoms include sore throat swollen glands in the neck fever weakness your doctor will diagnose it based on your signs and symptoms and a lab test. getting treatment for diphtheria quickly is important. if your doctor suspects that you have it, you'll start treatment before the lab tests come back. treatment is with antibiotics. the diphtheria, pertussis, and tetanus vaccine can prevent diphtheria, but its protection does not last forever. children need another dose, or booster, at about age 12. then, as adults, they should get a booster every 10 years. diphtheria is very rare in the united states because of the vaccine. centers for disease control and prevention

MalaCards based summary: Diphtheria, also known as corynebacterium infections, is related to psoriasis and granuloma annulare, and has symptoms including equilibration disorder, vertigo/dizziness and sore throat. An important gene associated with Diphtheria is HBEGF (Heparin Binding EGF Like Growth Factor), and among its related pathways are Uptake and actions of bacterial toxins and MAPK Pathway. The drugs equine diphtheria antitoxin and diphtheria antitoxin have been mentioned in the context of this disorder. Affiliated tissues include kidney, testes and skin, and related mouse phenotypes are integument and hematopoietic system.

Disease Ontology:11 A primary bacterial infectious disease that is characterized by sore throat, low fever, and an adherent membrane (a pseudomembrane) on the tonsils, pharynx, and/or nasal cavity. A milder form of diphtheria can be restricted to the skin. It is caused by Corynebacterium diphtheriae, an aerobic Gram-positive bacterium. Diphtheria toxin spreads through the bloodstream and can lead to potentially life-threatening complications that affect other organs of the body, such as the heart and kidneys.

CDC:2 Diphtheria once was a major cause of illness and death among children. The United States recorded 206,000 cases of diphtheria in 1921, resulting in 15,520 deaths. Starting in the 1920s, diphtheria rates dropped quickly due to the widespread use of vaccines. Between 2004 and 2015, 2 cases of diphtheria were recorded in the United States. However, the disease continues to cause illness globally. In 2014, 7,321 cases of diphtheria were reported worldwide to the World Health Organization, but many more cases likely go unreported.

Wikipedia:71 Diphtheria is an infection caused by the bacterium Corynebacterium diphtheriae. Signs and symptoms may... more...

Related Diseases for Diphtheria

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Diseases related to Diphtheria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 236)
idRelated DiseaseScoreTop Affiliating Genes
1psoriasis29.0CD40LG, CD79A
2granuloma annulare28.2ALB, CD40LG, CD79A
3hemolytic anemia28.1CD40LG, CD79A, CSF2, IL2, IL3
4rheumatoid arthritis28.1CD40LG, CD79A, CSF2, IL2, IL2RA
5systemic lupus erythematosus27.5ALB, CD40LG, CD79A, IL2, IL2RA
6asthma27.3CD40LG, CD79A, CSF2, IL13, IL2RA, IL3
7malaria27.3ALB, CD40LG, CSF2, IL13, IL2, IL2RB
8cutaneous diphtheria12.4
9pseudomembranous conjunctivitis10.8
10diphtheritic peritonitis10.8
11tetanus10.7
12pertussis10.7
13visual snow syndrome10.5IL2, IL2RB
14laryngeal cancer, childhood10.5CSF2, IL2RA
15graft-versus-host disease, protection against10.5IL2, IL2RA
16severe nonproliferative diabetic retinopathy10.4CSF2, IL3
17cyp2c19-related poor drug metabolism10.4CSF2, IL3
18influenza10.4
19haemophilus influenzae10.3
20hepatitis10.3
21hepatitis b10.3
22renal tubular acidosis10.3CSF2, IL2, IL2RA
23benign adult familial myoclonic epilepsy10.3CSF2, IL2RA, IL2RB
24poliomyelitis10.2
25fallopian tube disease10.2CD79A, IL2
26thomsen and becker disease10.2IL2, IL3
27scarlet fever10.2
28malignant histiocytic disease10.2CD79A, IL2, IL2RA
29calcific tendinitis10.2CD40LG, CD79A
30medullary sponge kidney10.2CD40LG, CD79A
31variola major10.1CD40LG, CD79A
32mu chain disease10.1CD40LG, CD79A
33retinal cancer10.1CD40LG, CD79A
34focal embolic glomerulonephritis10.1CD40LG, CD79A
35heart disease10.1CD40LG, CD79A
36endometrial stromal nodule10.1CD40LG, CD79A
37measles10.1
38chronic cystitis10.1CD40LG, CD79A
39van benthem-driessen-hanveld syndrome10.1CD40LG, CD79A
40leukemia10.1
41melanoacanthoma10.1CSF2, IL13, IL2
42hemolytic-uremic syndrome10.1CD40LG, CD79A
43partial motor epilepsy10.1CD40LG, CD79A
44benign meningioma10.1CD40LG, CD79A
45parasitic helminthiasis infectious disease10.1CD40LG, CD79A
46occlusion of gallbladder10.1CD40LG, CD79A
47neutropenia, severe congenital 3, autosomal recessive10.1CSF2, IL3
48viral meningitis10.1CD40LG, CD79A
49substance-induced psychosis10.1CD40LG, CD79A
50gamma heavy chain disease10.1CD40LG, CD79A

Graphical network of the top 20 diseases related to Diphtheria:



Diseases related to diphtheria

Symptoms & Phenotypes for Diphtheria

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UMLS symptoms related to Diphtheria:


equilibration disorder, vertigo/dizziness, sore throat, snoring, pruritus, coughing

MGI Mouse Phenotypes related to Diphtheria according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.5CD40LG, CSF2, EGF, HBEGF, IL13, IL2RB
2MP:00053978.1CD40LG, CD79A, CD9, CSF2, IL13, IL2
3MP:00053787.6CD9, CSF2, DPH3, EEF2, EGF, HBEGF
4MP:00053897.3CD40LG, CD9, CSF2, EGF, IL13, IL2
5MP:00053877.3CD40LG, CD79A, CD9, CSF2, EGF, IL13
6MP:00107687.1ALB, CD40LG, CSF2, DPH2, DPH3, EEF2

Drugs & Therapeutics for Diphtheria

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Drugs for Diphtheria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 165)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
IbuprofenapprovedPhase 450115687-27-13672
Synonyms:
(+-)-2-(P-Isobutylphenyl)propionic acid
(+-)-Ibuprofen
(+-)-P-Isobutylhydratropic acid
(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid
(4-Isobutylphenyl)-alpha-methylacetic acid
(RS)-ibuprofen
139466-08-3
15687-27-1
2-(4-Isobutylphenyl)propanoic acid
4-Isobutylhydratropic acid
58560-75-1
AC-11312
AC1L1GGE
AC1Q1P84
AC1Q1P85
ACHES-N-PAIN
ARONIS23835
Act-3
Actiprofen
Adex 200
Adran
Advil
Advil (TN)
Advil Liqui-Gels
Ak+C2278tren
Alaxan
Algofen
Am-Fam 400
Amelior
Amersol
Amibufen
Anafen
Anco
Andran
Anflagen
Antagil
Antalfene
Antarene
Antiflam
Apo-Ibuprofen
Apsifen
Apsifen-F
Artofen
Artril
Artril 300
BB_SC-1358
BIDD:GT0050
BRN 2049713
Balkaprofen
Betaprofen
Bloom
Bluton
Brofen
Brufanic
Brufen
Brufen 400
Bruflam
Brufort
Buburone
Bufeno
Bufigen
Bukrefen
Bupron
Buracaps
Burana
Butylenin
C01588
C13H18O2
CCRIS 3223
CHEBI:5855
CHEMBL521
CID3672
CPD000058184
Cap-Profen
Carol
Cesra
Children's Advil
Children's Elixsure
Children's Ibuprofen
Children's Motrin
Citalgan
Cobo
Codral
Combiflam
Cunil
D00126
D007052
DB01050
DOLO PUREN
Daiprophen
Dalsy
Dansida
Deep Relief
Dentigoa
Dibufen
Dignoflex
Dolgin
Dolgirid
Dolgit
Dolibu
Dolmaral
Dolo-Dolgit
Dolo-dolgit
Dolocyl
Dolofen
Dolofen-F
Dolofin
Dolofort
Dologel
Dolomax
Doloren
Dolormin
Doltibil
Dolven
Donjust B
Dorival
Drin
Duafen
Duobrus
Dura-Ibu
Duralbuprofen
Dysdolen
EU-0100691
Easifon
Ebufac
Emflam
Emflam-200
Emodin
Epobron
Eputex
Ergix
Esprenit
Exneural
Faspic
Femadon
Femafen
Femapirin
Femidol
Fenbid
Fenbid Spansule
Fendol
Fenspan
Fibraflex
Gelufene
Gofen
Grefen
Gynofug
HMS1920F15
HMS2089P05
HMS2091N03
HMS502M09
HSDB 3099
Haltran
I 4883
I01-7039
I0415
I4883_SIGMA
I7905_SIAL
IB-100
IDI1_000887
IP 82
IP-82
IP82
Ibol
Ibren
Ibu
Ibu-Attritin
Ibu-Slo
Ibu-Tab
Ibu-Tab 200
Ibu-attritin
Ibu-slo
Ibu-slow
Ibubest
Ibubeta
Ibucasen
Ibudol
 
Ibudolor
Ibufen
Ibuflamar
Ibufug
Ibugel
Ibugen
Ibugesic
Ibuhexal
Ibulagic
Ibular
Ibulav
Ibuleve
Ibulgan
Ibumed
Ibumerck
Ibumetin
Ibupirac
Ibuprin
Ibuprocin
Ibuprofen
Ibuprofene
Ibuprofeno
Ibuprofenum
Ibuprohm
Ibuprophen
Ibusal
Ibutid
Ifen
Inabrin
Inflam
Inoven
Ipren
Irfen
Isodol
Jenaprofen
Junifen
Junior Strength Advil
Junior Strength Ibuprofen
Junior Strength Motrin
KBio1_000887
KBio2_001329
KBio2_003897
KBio2_006465
KBio3_001390
Kesan
Kratalgin
LS-7454
Lamidon
Lebrufen
Librofem
Lidifen
Liptan
Lopane
MLS000069733
MLS001146965
Malafene
Manypren
Medipren
Melfen
Mensoton
Midol
Midol 200
Moment
Motrin
Motrin (TN)
Motrin IB
Mynosedin
NCI60_002065
NINDS_000887
NSC 256857
NSC256857
Nagifen-D
Napacetin
Narfen
Neo-Helvagit
Neo-Mindol
NeoProfen
Neobrufen
Nerofen
Noalgil
Nobafon
Nobfelon
Nobfen
Nobgen
Noritis
Norton
Novadol
Novo-Profen
Novogent
Novogent N
Novoprofen
Nuprilan
Nuprin
Nurofen
Optifen
Opturem
Oralfene
Ostarin
Ostofen
Ozonol
P-Isobutylhydratropic Acid
Paduden
Panafen
Pantrop
Para-Isobutylhydratropic Acid
Paxofen
Pedia-Profen
PediaProfen
Pediaprofen
Pediatric Advil
Perofen
Proartinal
Profen
Proflex
Provon
Quadrax
R.D. 13621
RD 13621
Rafen
Ranofen
Rebugen
Relcofen
Rhinadvil
Rofen
Roidenin
Rufen
Rufin
Rupan
SAM002264619
SMR000058184
SPBio_000178
STK177358
Sadefen
Salivia
Salprofen
Seclodin
Sednafen
Seklodin
Seskafen
Siyafen
Solpaflex
Solufen
Stelar
Sugafen
Suprafen
Suspren
Syntofene
TL8001184
Tab-Profen
Tabalon
Tabalon 400
Tatanal
Tempil
Tofen
Togal N
Tonal
Trendar
U 18573
U-18,573
U-18573
UCB 79171
Unipron
Upfen
Uprofen
Urem
VUFB 9649
Zafen
Zofen
alpha-(4-Isobutylphenyl)propionate
alpha-(4-Isobutylphenyl)propionic acid
alpha-(P-Isobutylphenyl)propionic acid
alpha-p-Isobutylphenylpropionate
alpha-p-Isobutylphenylpropionic acid
ibuprofen
p-Isobutyl-2-phenylpropionate
p-Isobutyl-2-phenylpropionic acid
p-Isobutylhydratropate
p-Isobutylhydratropic acid
2
Edetic Acidapproved, vet_approvedPhase 4, Phase 3, Phase 29560-00-4, 62-33-96049
Synonyms:
(ethylenedinitrilo)tetraacetic acid, ion(4−)
2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate
Acide ethylenediaminetetracetique
Acido edetico
Acidum edeticum
CaEDTA
Calcium Disodium Edetate (JAN)
Calcium Disodium Versenate
Calcium disodium versenate (TN)
 
EDT
EDTA
EDTA, ion(4-)
Edetate Calcium
Edetate calcium disodium (USP)
Ethylenediaminetetraacetate
Ethylenediaminetetraacetic acid
N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine)
acide edetique
{[-(bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid
3
AcetaminophenapprovedPhase 4, Phase 3978103-90-21983
Synonyms:
4'-Hydroxyacetanilide
4'-hydroxyacetanilide
4-(Acetylamino)phenol
4-Acetamidophenol
4-Acetaminophenol
4-Hydroxyacetanilide
4-Hydroxyanilid kyseliny octove
4-acetamidophenol
A-Per
A.F. Anacin
AC1Q1KYJ
AC1Q1KYK
APAP
Abenol
Abensanil
Abrol
Abrolet
Acamol
Accu-Tap
Acenol
Acephen
Acertol
Aceta Elixir
Aceta Tablets
Acetaco
Acetagesic
Acetalgin
Acetaminofen
Acetaminophen
Acetaminophen Uniserts
Acetamol
Acetavance
Acetofen
Actamin
Actamin Extra
Actamin Super
Actifed Plus
Actimol
Actimol Chewable Tablets
Actimol Children'S Suspension
Actimol Infants' Suspension
Actimol Junior Strength Caplets
Actron
Afebrin
Afebryl
Aferadol
Algesidal
Algina
Algomol
Algotropyl
Allay
Alpiny
Alpinyl
Alvedon
Amadil
Aminofen
Aminofen Max
Anacin
Anacin 3
Anacin-3
Anacin-3 Extra Strength
Anadin dla dzieci
Anaflon
Analter
Anapap
Andox
Anelix
Anexsia
Anexsia 10/660
Anexsia 5/325
Anexsia 7.5/325
Anexsia 7.5/650
Anhiba
Anoquan
Anti-Algos
Antidol
Anuphen
Apacet
Apacet Capsules
Apacet Elixir
Apacet Extra Strength Caplets
Apacet Extra Strength Tablets
Apacet Regular Strength Tablets
Apadon
Apamid
Apamide
Apitrelal
Apo-Acetaminophen
Arfen
Arthralgen
Asetam
Asomal
Aspac
Aspirin Free Anacin Maximum Strength Caplets
Aspirin Free Anacin Maximum Strength Gel Caplets
Aspirin Free Anacin Maximum Strength Tablets
Aspirin-Free Anacin
Aspirin-Free Excedrin Caplets
Asplin
Atasol
Atasol Caplets
Atasol Drops
Atasol Forte Caplets
Atasol Forte Tablets
Atasol Oral Solution
Atasol Tablets
Atralidon
Babikan
Bacetamol
Bancap
Bancap Hc
Banesin
Bayer Select
Bayer Select Allergy-Sinus
Bayer Select Head Cold
Bayer Select Headache Pain
Bayer Select Maximum Strength Headache Pain Relief Formula
Bayer Select Menstrual Multi-Symptom
Bayer Select Sinus Pain Relief
Ben-u-ron
Benmyo
Bickie-mol
Biocetamol
Bucet
Butalbital
Butapap
CCRIS 3
CHEBI:46195
Cadafen
Calapol
Calmanticold
Calonal
Calpol
Capital
Capital with Codeine
Captin
Causalon
Cefalex
Cetadol
Children'S Acetaminophen Elixir Drops
Children'S Acetaminophen Oral Solution
Children'S Tylenol Chewable
Claradol Codeine
Clixodyne
Co-Gesic
Cod-Acamol Forte
Codabrol
Codalgin
Codapane
Codicet
Codisal
Codisal Forte
Codoliprane
Codral Pain Relief
Cofamol
Conacetol
Contac Cough & Sore Throat Formula
Contra-Schmerz P
Coricidin
Coricidin D
Coricidin Sinus
Cosutone
Croix Blanche
Cuponol
Curadon
Curpol
Custodial
D oliprane
Dafalgan
Dapa
Dapa X-S
Darocet
Darvocet
Darvocet-N 50
Datril
Datril Extra-Strength
Daygrip
Demilets
Deminofen
Democyl
Demogripal
Desfebre
Dhamol
Dhc Plus
Dial-a-gesic
Dial-alpha-gesic
Dimindol
Dirox
Disprol
Dol-Stop
Dolcor
Dolefin
Dolegrippin
Dolene AP-65
Dolene Ap-65
Dolgesic
Doliprane
Dolko
Dolofugin
Doloreduct
Dolorfug
Dolorol Forte
Dolorstop
Dolotec
Dolprone
Dorocoff
Dresan
Dristan Cold No Drowsiness
Dristancito
Drixoral Plus
Duaneo
Dularin
Duorol
Duracetamol
Duradyne Dhc
Durapan
Dymadon
Dymadon Co
Dymadon Forte
Dypap
Ecosetol
Elixodyne
Empracet
Endecon
Enelfa
Eneril
Esgic
Esgic-Plus
Eu-Med
Excedrin
Excedrin Caplets
Excedrin Extra Strength Caplets
Excipain
Exdol
Exdol Strong
Fanalgic
Farmadol
Febranine
Febrectal
Febrectol
Febrex
Febricet
Febridol
Febrilix
Febrin
Febrinol
Febro-Gesic
Febrolin
Femcet
Fendon
Fensum
Fepanil
Fever All
Feverall
Feverall Junior Strength
Feverall Sprinkle Caps Junior Strength
Fevor
Finimal
Finiweh
Fioricet
Fluparmol
Fortalidon P
Freka-cetamol
Gattaphen T
Gelocatil
Geluprane
Genapap
Genapap Children'S Elixir
Genapap Children'S Tablets
Genapap Extra Strength Caplets
Genapap Extra Strength Tablets
Genapap Regular Strength Tablets
Genebs
Genebs Extra Strength Caplets
Genebs Regular Strength Tablets
Genebs X-Tra
Geralgine-P
Gripin Bebe
Grippostad
Gynospasmine
Hedex
Helon N
Homoolan
Hy-Phen
Hycomine Compound
Hydrocet
Ildamol
Inalgex
Infadrops
Infants' Feverall
Influbene N
Injectapap
Intensin
Janupap
Jin Gang
Junior Disprol
KBio1_000660
Kataprin
Kinder Finimal
Korum
Kratofin simplex
L024125
Labamol
Lekadol
Lemgrip
Lemsip
Lestemp
Liqiprine
Liquagesic
Liquigesic Co
Liquiprin
Liquiprin Children'S Elixir
Liquiprin Infants" Drops
Lonarid
Lonarid Mono
Lorcet-Hd
Lortab
Lupocet
Lyteca
Lyteca Syrup
Magnidol
Malex N
Malgis
Malidens
Maxadol
Medigesic Plus
Medinol Paediatric
Medocodene
Melabon Infantil
Mexalen
Midol Maximum Strength
Midol PM Night Time Formula
Midol Regular Strength
Midol Teen Formula
Migraleve Yellow
Minafen
Minoset
Miralgin
Momentum
Mono Praecimed
 
Multin
N-(4-Hydroxyphenyl)acetamide
N-Acetyl-4-aminophenol
N-Acetyl-p-aminophenol
N-acetyl-p-aminophenol
NAPA
NCX 701
NEBS
NSC3991
Naldegesic
Napafen
Napap
Naprinol
Nealgyl
Nebs
Neo-Fepramol
NeoCitran
Neodol
Neodolito
Neopap
Neotrend
Neuridon
New Cortal for Children
NilnOcen
Nina
No-Febril
Nobedon
Nodolex
Noral
Norcet
Norco
O-Acetaminophenol
Ofirmev
Oltyl
Oralgan
Oraphen-PD
Ortensan
Oxycet
Oxycocet
Oxycodone 2.5/Apap 500
Oxycodone 5/Apap 500
PCM Paracetamol Lichtenstein
Paceco
Pacemo
Pacemol
Pacet
Pacimol
Paedialgon
Paedol
Painex
Paldesic
Pamol
Panacete
Panadeine
Panadeine Co
Panadiene
Panado-Co
Panado-Co Caplets
Panadol
Panadol Extra Strength
Panadol Junior Strength Caplets
Panadol Maximum Strength Caplets
Panadol Maximum Strength Tablets
Panale ve
Panaleve
Panamax
Panasorb
Panasorbe
Panets
Panex
Panodil
Panofen
Pantalgin
Papa-Deine
Papa-Deine #3
Papa-Deine #4
Para-Suppo
Para-Tabs
Paracemol
Paracenol
Paracet
Paracetamol
Paracetamol AL
Paracetamol Antipanin P
Paracetamol BC
Paracetamol Basics
Paracetamol DC
Paracetamol Dr. Schmidgall
Paracetamol Fecofar
Paracetamol Genericon
Paracetamol Hanseler
Paracetamol Harkley
Paracetamol Heumann
Paracetamol Hexal
Paracetamol Italfarmaco
Paracetamol Nycomed
Paracetamol PB
Paracetamol Raffo
Paracetamol Ratiopharm
Paracetamol Rosch
Paracetamol Saar
Paracetamol SmithKline Beecham
Paracetamol Stada
Paracetamol Winthrop
Paracetamol von ct
Paracetamole
Paracetamolo
Paracetamolum
Paracetanol
Paracetol
Paracin
Paracod
Paracodol
Paracétamol
Parador
Paradrops
Parakapton
Parake
Paralen
Paralief
Paralink
Paralyoc
Paramol
Paramolan
Paranox
Parapan
Parasedol
Parasin
Paraspen
Parcetol
Parelan
Parmol
Parogal
Paroma
Pasolind
Pasolind N
Pe-Tam
Pediapirin
Pediatrix
Pedric
Percocet
Percocet-5
Percocet-Demi
Percogesic with Codeine
Perdolan Mono
Perfalgan
Phenaphen
Phenaphen Caplets
Phenaphen W/Codeine
Phendon
Phenipirin
Phogoglandin
Phrenilin
Phrenilin Forte
Pinex
Piramin
Pirinasol
Plicet
Polmofen
Predimol
Predualito
Prestwick_13
Prodol
Prompt
Prontina
Propacet
Propacet 100
Proval #3
Puernol
Pulmofen
Pyregesic-C
Pyrigesic
Pyrinazine
Pyromed
Quiet World
Redutemp
Reliv
Remedol
Rhinex D-Lay Tablets
Rivalgyl
Robigesic
Robitussin Night Relief
Rockamol Plus
Rounox
Roxicet
Roxicet 5/500
Roxilox
RubieMol
Rubophen
Rupemol
SK-Apap
SPBio_002836
Salzone
Sanicet
Sanicopyrine
Scanol
Scentalgyl
Scherzatabletten Rezeptur 534
Schmerzex
Sedalito
Sedapap
Semolacin
Servigesic
Seskamol
Setakop
Setamol
Setol
Sifenol
Sinaspril
Sine-Off Sinus Medicine Caplets
Sinedol
Sinmol
Sinubid
Snaplets-FR
Spalt N
Spalt fur die nacht
St Joseph Aspirin-Free
St Joseph Aspirin-Free for Children
St. Joseph Cold Tablets for Children
St. Joseph Fever Reducer
Stanback
Stopain
Sudafed Severe Cold Formula
Sudafed Sinus
Sunetheton
Supac
Supadol mono
Supofen
Suppap
Suppap-120
Suppap-325
Suppap-650
Supramol-M
Synalgos-Dc-A
TYL
Tabalgin
Tachiprina
Talacen
Tapanol
Tapanol Extra Strength Caplets
Tapanol Extra Strength Tablets
Tapar
Tavist Allergy/Sinus/Headache
Tazamol
Temlo
Tempanal
Tempra
Tempra Caplets
Tempra Chewable Tablets
Tempra D.S
Tempra Drops
Tempra Syrup
Tencon
Termacet
Termalgin
Termalgine
Termofren
TheraFlu
Tibinide
Tibizide
Tiffy
Tisin
Tisiodrazida
Titralgan
Tizide
Tocris-1706
Toximer P
Tralgon
Treupel N
Treupel mon
Treuphadol
Triad
Triaminic Sore Throat Formula
Triaprin
Tricoton
Tussapap
Ty lenol
Tycolet
Tylenol
Tylenol (TN)
Tylenol Allergy Sinus
Tylenol Arthritis Extended Relief
Tylenol Caplets
Tylenol Children'S Chewable Tablets
Tylenol Children'S Elixir
Tylenol Children'S Suspension Liquid
Tylenol Drops
Tylenol Elixir
Tylenol Extra Strength Adult Liquid Pain Reliever
Tylenol Extra Strength Caplets
Tylenol Extra Strength Gelcaps
Tylenol Extra Strength Tablets
Tylenol Gelcaps
Tylenol Infants Drops
Tylenol Infants" Suspension Drops
Tylenol Junior Strength Caplets
Tylenol Junior Strength Chewable Tablets
Tylenol Regular Strength Caplets
Tylenol Regular Strength Tablets
Tylenol Tablets
Tylex
Tylex CD
Tylol
Tylox
Tylox-325
Tymol
Ultracet
Upsanol
Utragin
Valadol
Valgesic
Valorin
Valorin Extra
Vanquish
Veralgina
Vermidon
Verpol
Viclor Richet
Vicodin
Vicodin Es
Vicodin Hp
Vips
Viruflu
Vivimed
Volpan
Wygesic
Zatinol
Zolben
acetaminofén
acétaminophène
alpha-Per
p-(Acetylamino)phenol
p-Acetamidophenol
p-Acetaminophenol
p-Acetylaminophenol
p-Hydroxyacetanilide
p-Hydroxyphenolacetamide
p-acetamidophenol
p-acetaminophenol
p-hydroxy-acetanilid
p-hydroxyacetanilide
p-hydroxyphenolacetamide
4
Daclizumabapproved, investigationalPhase 498152923-56-3
Synonyms:
 
Dacliximab
Daclizumab beta
5
Etanerceptapproved, investigationalPhase 4397185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
6
AdalimumabapprovedPhase 4478331731-18-116219006
Synonyms:
331731-18-1
Adalimumab
Adalimumab (USAN/INN)
Adalimumab (genetical recombination)
 
Adalimumab (genetical recombination) (JAN)
D02597
Humira
Humira (TN)
Humira Pen
Ig gamma-1 chain C region
7
Natalizumabapproved, investigationalPhase 497189261-10-7
Synonyms:
189261-10-7
Anti-VLA4
Anti-alpha4 integrin
 
D06886
Natalizumab
Natalizumab (INN)
Tysabri
Tysabri (TN)
8
IronapprovedPhase 4, Phase 3, Phase 211237439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
 
Ed-In-Sol
Eisen
Electrolytic iron
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feronate
Ferretts
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
Ferrum metallicum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron powder
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, carbonyl
Iron, electrolytic
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
Iron, reduced
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Reduced iron
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Vitedyn-Slo
Yieronia
fer
ferrous iron
hierro
9
Ritonavirapproved, investigationalPhase 4870155213-67-5392622
Synonyms:
1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
155213-67-5
1hxw
1sh9
5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S)-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate
5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate
538, ABT
A-84538
ABBOTT-84538
ABT 538
ABT 84538
ABT-538
ABT538
AC-733
AC1L94GB
AKOS000280930
Abbott 84538
BIDD:GT0387
BIDD:PXR0023
Bio-0093
C07240
C37H48N6O5S2
CHEBI:45409
CHEMBL163
CID392622
CPD000466395
D00427
D019438
 
DB00503
DRG-0244
FT-0082824
HMS2051B08
HSDB 7160
LS-148860
MLS000759541
MLS001424063
MolPort-000-883-877
N-[(2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl]-N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-L-valinamide
NCGC00159462-02
NSC693184
Norvir
Norvir (TM)
Norvir (TN)
Norvir Sec
RIT
RTV
Ritonavir
Ritonavir (JAN/USAN/INN)
Ritonavir [USAN]
Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS.
Ritonavirum
S1185_Selleck
SAM001246783
SMR000466395
STK634209
ZINC03944422
ritonavir
10
Tenofovirapproved, investigationalPhase 4733147127-20-6464205
Synonyms:
(R)-9-(2-Phosphonomethoxypropyl)adenine
(R)-9-(2-Phosphonylmethoxypropyl)adenine
(R)-9-(2-phosphonomethoxypropyl)adenine
(R)-PMPA
147127-20-6
206184-49-8
AC-760
AC1LA9BO
Anh. tenofovir
Anhydrous tenofovir
Apropovir
CHEBI:45809
CHEMBL483
CID464205
D,L-Tenofovir
DB00300
GNA & Tenofovir
GS 1275
GS 1278
GS1278
 
HHA & Tenofovir
KS-5021
MolPort-003-850-411
NCGC00167535-01
PMPA
PMPA-(R)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Galanthus nivalis agglutinin (GNA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Hippeastrum hybrid agglutinin( HHA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- (9CI)
Phosphonic acid, [[2-(6-amino-9H-purin-9
S1401_Selleck
TDF
TFV
Tenefovir
Tenofovir
Tenofovir (anh.)
Tenofovir disoproxil
Tenofovir disoproxil fumarate
UNII-99YXE507IL
Viread
Viread, Tenofovir
[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
11
Emtricitabineapproved, investigationalPhase 4439143491-57-060877
Synonyms:
(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-.beta.-L-FTC
(-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine
(-)-2'-Deoxy-5-fluoro-3'-thiacytidine
(-)-FTC
(-)-beta-2',3'-Dideoxy-5-fluoro-3'-thiacytidine
(-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine
(-)-cis-4-amino-5-Fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
(-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
(2R-cis)-4-Amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
(2R-cis)-4-amino-5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
.beta.-L-(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
1-(2-(Hydroxymethyl)oxathiolan-5-yl)-5-fluorocytosine
143491-54-7
143491-57-0
145213-48-5
2',3',5-FTC
2',3'-Dideoxy-5-fluoro-3'-thiacytidine
2'-Deoxy-5-fluoro-3'-oxa-4'-thiocytidine
2'-Deoxy-5-fluoro-3'-thiacytidine
2-FTC
3'-Thia-2'.3'-dideoxy-5-fluorocytidine
4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one
4-Amino-5-fluoro-1-[(2R,5S)-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
4-amino-5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)[1,3]oxathiolan-5-yl]cytosine
524W91
AC1L1U3I
AC1Q4KUB
BW 1592
 
BW 524W91
BW-524W91
BW524W91
C122114
C12599
C8H10FN3O3S
CHEBI:31536
CHEMBL885
CID60877
Coviracil
Coviracil(TM)
D01199
DB00879
DRG-0208
Emtricitabin
Emtricitabina
Emtricitabine
Emtricitabine (JAN/USAN/INN)
Emtricitabinum
Emtriva
Emtriva (TN)
Emtriva(TM)
FT-0080009
HMS2089I05
HSDB 7337
LS-135838
LS-173184
NCGC00164564-01
RCV
Racivir
SBB066061
TL8000958
UNII-G70B4ETF4S
ZINC03629271
beta-L-2',3'-dideoxy-5-fluoro-3'-thiacytidine
dOTFC
emtricitabine
12
LopinavirapprovedPhase 4342192725-17-092727
Synonyms:
(1S-(1R*(R*),3R*,4R*))-N-(4-(((2,6-Dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
(2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
(alphaS)-Tetrahydro-N-((alphaS)-alpha-((2S,3S)-2-hydroxy-4-phenyl-3-(2-(2,6-xylyloxy)acetamido)butyl)phenethyl)-alpha-isopropyl-2-oxo-1(2H)-pyrimidineacetamide
1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-alpha-(1-methylethyl)-2-oxo-, (alphaS)- (9CI)
192725-17-0
1mui
2o4s
2q5k
2rkf
2rkg
A 157378
A 157378.0
A-157378-0
A-157378.0
AB1
ABT 157378
ABT 378
ABT-378
ABT-378, LOPINAVIR
AC1L3OPJ
AIDS032937
 
Aluviran
C12871
C37H48N4O5
CHEBI:40456
CHEMBL729
CID92727
D01425
DB01601
Koletra
LPV
LS-173766
Lopinavir
Lopinavir (JAN/USAN/INN)
Lopinavir [USAN:INN:BAN]
MolPort-003-848-410
N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide
N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE
NCGC00164576-01
NCGC00164576-02
RS-346
S1380_Selleck
UNII-2494G1JF75
13
Efavirenzapproved, investigationalPhase 4405154598-52-464139
Synonyms:
(-)-6-CHLORO-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one
(-)-Efavirenz
(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
(4S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
(4S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one
(S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-ben
(S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
(S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
(S)-6-chloro-4-(Cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
(S)-6-chloro-4-Cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[D][1,3]oxazin-2-one
154598-52-4
1ikv
1ikw
2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)- (9
6-chloro-4-(2-Cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[D][1,3]oxazin-2-one
6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one
AC-19049
AC1L20IX
BIDD:GT0383
C08088
C14H9ClF3NO2
CHEBI:119486
CHEMBL223228
CID64139
CPD000466351
D00896
DB00625
DB07709
DMP 266
DMP-266
EFV
 
EFZ
Efavirenz
Efavirenz (JAN/INN)
Efavirenzum
Eravirenz
HMS2051J08
HMS2090N16
HSDB 7163
L 743726
L-741211
L-743,726
L-743725
L-743726
LS-173464
MLS000759465
MLS001424087
Met-SDF-1.beta. & Efavirenz
Met-Stromal Cell-derived Factor-1.beta. (Human) & Efavirenz
MolPort-003-983-924
NSC742403
SAM001246667
SBB066062
SMR000466351
Stocrin
Strocin (TM)
Sustiva
Sustiva (TM)
Sustiva (TN)
UNII-JE6H2O27P8
ZINC02020233
efavirenz
efavirenz, (S)-isomer
zoxazin-2-one
Éfavirenz
14Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 2, Phase 16260
15Protective AgentsPhase 4, Phase 3, Phase 27190
16Heptavalent Pneumococcal Conjugate VaccinePhase 4, Phase 3, Phase 2, Phase 1454
17Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 122776
18VaccinesPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 16428
19AnalgesicsPhase 4, Phase 3, Phase 2, Phase 111287
20Antibodies, MonoclonalPhase 4, Phase 23795
21BCG VaccinePhase 4, Phase 2103
22Anti-Retroviral AgentsPhase 4, Phase 13232
23AntipyreticsPhase 4, Phase 31534
24Immunosuppressive AgentsPhase 4, Phase 212770
25Anti-Infective AgentsPhase 4, Phase 3, Phase 2, Phase 121402
26Anti-Ulcer AgentsPhase 4, Phase 3, Phase 2, Phase 11767
27AntacidsPhase 4, Phase 3, Phase 2, Phase 11767
28Aluminum phosphatePhase 4, Phase 3, Phase 1, Phase 232
29Cyclooxygenase InhibitorsPhase 42778
30Antiviral AgentsPhase 4, Phase 3, Phase 2, Phase 19732
31Anti-HIV AgentsPhase 4, Phase 13100
32Immunoglobulin GPhase 4265
33AntidotesPhase 4, Phase 3, Phase 21038
34Calcium, DietaryPhase 4, Phase 3, Phase 25525
35AntitoxinsPhase 4, Phase 312
36
LactitolPhase 4, Phase 3, Phase 2332585-86-43871
Synonyms:
4-O-b-D-Galactopyranosyl-D-glucitol, 9CI
E966
Emportal
 
Floralac
Importal
Oponaf
Portolac
37AnticoagulantsPhase 4, Phase 3, Phase 22516
38Keyhole-limpet hemocyaninPhase 4, Phase 145
39Adjuvants, ImmunologicPhase 4, Phase 3, Phase 2, Phase 12484
40Diphtheria AntitoxinPhase 4, Phase 33
41Gastrointestinal AgentsPhase 4, Phase 3, Phase 2, Phase 18109
42Chelating AgentsPhase 4, Phase 3, Phase 21365
43ImmunoglobulinsPhase 4, Phase 3, Phase 2, Phase 16045
44AntibodiesPhase 4, Phase 3, Phase 2, Phase 16045
45MF59 oil emulsionPhase 4, Phase 2101
46Anti-Inflammatory AgentsPhase 4, Phase 310355
47Anti-Inflammatory Agents, Non-SteroidalPhase 44295
48Iron Chelating AgentsPhase 4, Phase 3, Phase 2222
49Interleukin 1 Receptor Antagonist ProteinPhase 496
50Antirheumatic AgentsPhase 4, Phase 210627

Interventional clinical trials:

(show top 50)    (show all 503)
idNameStatusNCT IDPhase
1An Immunogenicity and Safety Study of Tetanus, Diphtheria and Acellular Pertussis Vaccine BoosterUnknown statusNCT00870350Phase 4
2Vaccination Against Pertussis, Tetanus and Diphtheria in Patients Suffering From Rheumatoid ArthritisUnknown statusNCT01301703Phase 4
3The Safety and Immunogenicity of Acellular Pertussis Vaccine in Bone Marrow Transplant RecipientsUnknown statusNCT00336115Phase 4
4Safety, Long Term Immunogenicity and Lot Consistency Study of Liquid Pentavalent Combination VaccineUnknown statusNCT00877357Phase 4
5Canadian Manufactured Tetanus and Diphtheria Toxoids Adsorbed (Td) Vaccine Compared With U.S. Manufactured TdCompletedNCT00601835Phase 4
6Immunogenicity and Safety Study of a Booster Dose (5th) of Diphteria-Tetanus-Pertussis-Polio VaccineCompletedNCT00514059Phase 4
7Immune Responses in Adults to Revaccination With ADACEL® 10 Years After a Previous DoseCompletedNCT00712959Phase 4
8Immunogenicity and Safety of Concomitant Administration of RotaTeq™ (V260) and the Diphtheria, Tetanus, Pertussis and Inactivated Poliovirus Vaccine (DTP-IPV) in Healthy Japanese Infants (V260-060)CompletedNCT01926015Phase 4
9Descriptive, Open-label, Multicenter Study of the Safety of Redosing With ADACEL® VaccineCompletedNCT00347958Phase 4
10Phase IV Interchangeability Study of a Liquid Pentavalent Combination VaccineCompletedNCT00674908Phase 4
11A Trial to Evaluate the Safety and Immunogenicity of ADACEL® Vaccine in Persons 65 Years of Age and OlderCompletedNCT00457249Phase 4
12Study of Menactra® in Healthy Subjects at 9 Months and Concomitantly With Pentacel® at 15 to 18 Months of AgeCompletedNCT01659996Phase 4
13Post-licensure, Modified Double-blind, Multi-center Study Evaluating Safety and Immunogenicity of ADACEL® and BOOSTRIX®CompletedNCT00319553Phase 4
14Study of Adacel® Vaccine Administered to Persons 10 Years of AgeCompletedNCT01311557Phase 4
15Immunogenicity of Adacel® and BOOSTRIX® Vaccines in AdolescentsCompletedNCT01629589Phase 4
16Post-marketing Evaluation of Reactions Following Receipt of Recommended Adolescent Pertussis VaccineCompletedNCT00304265Phase 4
17Post Marketing Surveillance for ADACEL™ in South KoreaCompletedNCT01137435Phase 4
18A Phase 4, Placebo-Controlled, Randomized Study to Evaluate the Immunogenicity and Safety of HPV and Tdap When Administered With MenACWY in AdolescentsCompletedNCT01424644Phase 4
19Antibody Persistence to REVAXIS or DT Polio and Immune Response to TETRAVAC-ACELLULAIRECompletedNCT01546909Phase 4
20Study of Menactra® in US Adolescents When Administered Concomitantly With Tdap VaccineCompletedNCT00777257Phase 4
21A Trial Evaluating a 7-valent Pneumococcal Conjugate Vaccine Given With Diphtheria, Tetanus, and Acellular Pertussis Vaccine (DTaP) in Healthy Japanese Infants.CompletedNCT01250756Phase 4
22Regulatory Post-Marketing Surveillance Study for TETRAXIM™CompletedNCT01437423Phase 4
23US-licensed Combined Vaccine Against Tetanus & Diphtheria, Given With US-licensed Vaccine Against Meningococcal DiseaseCompletedNCT00282295Phase 4
24Study of DAPTACEL® Administered as a 5th Dose in 4 to 6-Year-Old Children Previously Immunized With PENTACEL™CompletedNCT00802867Phase 4
25Randomized Study of Not Giving Diphteria-tetanus-pertussis Vaccination With or After Measles VaccinationCompletedNCT00244673Phase 4
26Safety and Immunogenicity Study of a Liquid Pentavalent Combination VaccineCompletedNCT00617812Phase 4
27Assessment of the Immunogenicity and Safety of PENTAXIM™ in PhilippinesCompletedNCT00254917Phase 4
28Concomitant Use of Hepatitis A Vaccine, Inactivated With Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate) and Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed Given to Healthy Children 15 Months of Age (V251-068)CompletedNCT00289913Phase 4
29Study to Assess if Quinvaxem Can be Interchanged With Other Pentavalent Vaccines During Standard Childhood VaccinationCompletedNCT01357720Phase 4
30Post-Marketing Safety Study of Menactra® in Healthy Children, Adolescents, and Adults in the PhilippinesCompletedNCT01270503Phase 4
31Immunogenicity & Reactogenicity of Boostrix 10 Years After Previous Booster Vaccination.CompletedNCT00610168Phase 4
32Persistence of Immunogenicity of MenACWY Conjugate Vaccine 5 Years After Childhood Vaccination, and Immune Response to a Booster DoseCompletedNCT01823536Phase 4
33Immunogenicity & Reactogenicity of Boostrix 10 Years After Previous Booster VaccinationCompletedNCT00548171Phase 4
34Immunogenicity and Safety of Sanofi Pasteur Pentaxim Combined Vaccine in Infants in ThailandCompletedNCT00255021Phase 4
35Evaluation of Boostrix™10 Years After Previous Booster VaccinationCompletedNCT01147900Phase 4
36Immunogenicity and Safety of TETRAXIM™ Given as a Booster Dose at 4 to 6 Years of AgeCompletedNCT01031303Phase 4
37The Effects of Tysabri Treatment on Vaccination Response and Lymphocyte Subsets in Subjects With Relapsing Forms of Multiple SclerosisCompletedNCT00536120Phase 4
38Immunogenicity and Safety of Booster Dose of BoostrixTM Polio Vaccine in Previously Boosted AdultsCompletedNCT01323959Phase 4
39Immunogenicity and Reactogenicity Study of BoostrixTM (dTpa) and Boostrix-IPV (dTpa-IPV)CompletedNCT01294605Phase 4
40Descriptive, Post-marketing, Surveillance Safety Study of Menactra VaccineCompletedNCT00254995Phase 4
41Immunology of Non-specific Effects of VaccineCompletedNCT00168545Phase 4
42Immunogenicity and Safety of BoostrixTM Using a New Syringe in 10 to 15-year Old AdolescentsCompletedNCT01362322Phase 4
43Study Evaluating Prevenar Vaccine in Healthy InfantsCompletedNCT00276107Phase 4
44Persistence of Bactericidal Antibodies in Adults Who Received a Booster Dose of Menactra® Approximately 4 Years EarlierCompletedNCT02633787Phase 4
45Safety and Immunogenicity of a Booster Dose of GSK Biological's Boostrix-Polio VaccineCompletedNCT00635128Phase 4
46Study of a New Formulation of DTPa-HBV-IPV/Hib Vaccine Administered as a Booster Dose to 18-23 Months Old ChildrenCompletedNCT00611559Phase 4
47Safety of PENTAXIM® Given as a Three-Dose Primary Vaccination at 2, 3, and 4 Months of Age in Infants in ChinaCompletedNCT01491087Phase 4
48Evaluating the Effect of Anakinra (r-metHuIL-1ra) on Vaccine AntibodyResponse in Subjects With Rheumatoid Arthritis (RA)CompletedNCT00111410Phase 4
49Retrospective Survey of Safety of Fourth Dose Pentacel® in ChildrenCompletedNCT00772369Phase 4
50Assess the Safety & Reactogenicity of DTPa-IPV/Hib Vaccine Administered at 3, 4, 5 & 18 Mths of Age, in Healthy InfantsCompletedNCT00325156Phase 4

Search NIH Clinical Center for Diphtheria

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: corynebacterium infections

Genetic Tests for Diphtheria

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Anatomical Context for Diphtheria

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MalaCards organs/tissues related to Diphtheria:

36
Kidney, Testes, Skin, Heart, Lymph node, Tonsil, Eye

Publications for Diphtheria

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Articles related to Diphtheria:

(show top 50)    (show all 867)
idTitleAuthorsYear
1
Receptor-Mediated Enhanced Cellular Delivery of Nanoparticles Using Recombinant Receptor-Binding Domain of Diphtheria Toxin. (27959571)
2017
2
Augmentation of humoral and cellular immunity in response to Tetanus and Diphtheria toxoids by supercritical carbon dioxide extracts of Hippophae rhamnoides L. leaves. (28092864)
2017
3
Demand- and supply-side determinants of diphtheria-pertussis-tetanus nonvaccination and dropout in rural India. (28081971)
2017
4
Life-saving diphtheria drug is running out. (28082541)
2017
5
Process optimization for an industrial-scale production of Diphtheria toxin by Corynebacterium diphtheriae PW8. (27640957)
2016
6
Evaluation of the Immunogenicity of Diphtheria Toxoid Conjugated to Salmonella Typhimurium-Derived OPS in a Mouse Model: A Potential Vaccine Candidate Against Salmonellosis. (27660722)
2016
7
Undervaccination with diphtheria, tetanus, and pertussis vaccine: National trends and association with pertussis risk in young children. (27858500)
2016
8
Immunological characterization of diphtheria toxin recovered from Corynebacterium pseudotuberculosis. (26981011)
2016
9
Enhanced surveillance of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccines in pregnancy in the Vaccine Adverse Event Reporting System (VAERS), 2011-2015. (27013434)
2016
10
Effect of Tetanus-diphtheria Vaccine on Immune Response to Hepatitis B Vaccine in Low-responder Individuals. (27563430)
2016
11
Cost-effectiveness analysis of universal maternal immunization with tetanus-diphtheria-acellular pertussis (Tdap) vaccine in Brazil. (26899375)
2016
12
CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin. (27184067)
2016
13
Post-licensure safety surveillance study of routine use of tetanus toxoid, reduced diphtheria toxoid and 5-component acellular pertussis vaccine. (27388557)
2016
14
Vaccine effectiveness of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine during a pertussis outbreak in Maine. (27038131)
2016
15
Sex-differential effects on mortality of BCG and diphtheria-tetanus-pertussis vaccines in a rural area with high vaccination coverage: observational study from Senegal. (27738283)
2016
16
Immune Thrombocytopenia Following Diphtheria Pertussis- Tetanus and Oral Polio Vaccine. (27771689)
2016
17
Effect of introduction of pentavalent vaccine as replacement for Diphtheria-Tetanus-Pertussis and Hepatitis B vaccines on vaccination uptake in a health facility in Nigeria. (27108191)
2016
18
Dmp1 Promoter-Driven Diphtheria Toxin Receptor Transgene Expression Directs Unforeseen Effects in Multiple Tissues. (28035954)
2016
19
Immunogenicity, Safety, and Tolerability of Bivalent rLP2086 Meningococcal Group B Vaccine Administered Concomitantly With Diphtheria, Tetanus, and Acellular Pertussis and Inactivated Poliomyelitis Vaccines to Healthy Adolescents. (26803328)
2016
20
Expression and purification of truncated diphtheria toxin, DT386, in Escherichia coli: An attempt for production of a new vaccine against diphtheria. (27920826)
2016
21
Public health action following an outbreak of toxigenic cutaneous diphtheria in an Auckland refugee resettlement centre. (28043222)
2016
22
A Bordetella pertussis proteoliposome induces protection in mice without affecting the immunogenicity of diphtheria and tetanus toxoids in a trivalent formulation. (27489808)
2016
23
A Belgian Serosurveillance/Seroprevalence Study of Diphtheria, Tetanus and Pertussis Using a Luminex xMAP Technology-Based Pentaplex. (27171114)
2016
24
Potency of a human monoclonal antibody to diphtheria toxin relative to equine diphtheria anti-toxin in a guinea pig intoxication model. (27070129)
2016
25
Recent Outbreaks of Diphtheria in Dibrugarh District, Assam, India. (27630847)
2016
26
Tetanus, diphtheria, and acellular pertussis vaccination among women of childbearing age-United States, 2013. (27372388)
2016
27
Diphtheria Toxin-Induced Cell Death Triggers Wnt-Dependent Hair Cell Regeneration in Neonatal Mice. (27605621)
2016
28
High level accumulation of soluble diphtheria toxin mutant (CRM197) with co-expression of chaperones in recombinant Escherichia coli. (27020286)
2016
29
Safety and immunogenicity of a booster dose of meningococcal (groups A, C, W, and Y) polysaccharide diphtheria toxoid conjugate vaccine. (27642132)
2016
30
Diphtheria outbreak in Lao People's Democratic Republic, 2012-2013. (27422343)
2016
31
Employers' Views on Influenza and Tetanus-Diphtheria-Pertussis Vaccination in the Workplace. (27058495)
2016
32
Ablation of Pericyte-like Cells in Lungs by Oropharyngeal Aspiration of Diphtheria Toxin. (27779900)
2016
33
Immunogenicity of MenACWY-CRM in Korean Military Recruits: Influence of Tetanus-Diphtheria Toxoid Vaccination on the Vaccine Response to MenACWY-CRM. (27593883)
2016
34
Semicarbazone EGA Inhibits Uptake of Diphtheria Toxin into Human Cells and Protects Cells Articlefrom Intoxication. (27428999)
2016
35
The pH-Dependent Trigger in Diphtheria Toxin T Domain Comes with a Safety Latch. (27806276)
2016
36
More than 20 years after re-emerging in the 1990s, diphtheria remains a public health problem in Latvia. (27934582)
2016
37
Does vaccination ensure protection? Assessing diphtheria and tetanus antibody levels in a population of healthy children: A cross-sectional study. (27930568)
2016
38
Primary cutaneous diphtheria: management, diagnostic workup, and treatment as exemplified by a rare case report. (27373251)
2016
39
Durability of Vaccine-Induced Immunity Against Tetanus and Diphtheria Toxins: A Cross-sectional Analysis. (27060790)
2016
40
The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration. (28032302)
2016
41
Genome-Wide Association Mapping of the Antibody Response to Diphtheria-Tetanus-acellular Pertussis Vaccine in Mice. (28011915)
2016
42
Impact of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccinations on Reported Pertussis Cases Among Those 11 to 18 Years of Age in an Era of Waning Pertussis Immunity: A Follow-up Analysis. (27018748)
2016
43
A Phase 2, Randomized, Active-controlled, Observer-blinded Study to Assess the Immunogenicity, Tolerability and Safety of Bivalent rLP2086, a Meningococcal Serogroup B Vaccine, Coadministered With Tetanus, Diphtheria and Acellular Pertussis Vaccine and Serogroup A, C, Y and W-135 Meningococcal Conjugate Vaccine in Healthy US Adolescents. (26974889)
2016
44
Tetanus and diphtheria immunity in refugees in Europe in 2015. (27541038)
2016
45
Impact and cost-effectiveness of a second tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine dose to prevent pertussis in the United States. (26899377)
2016
46
Is diphtheria-tetanus-pertussis (DTP) associated with increased female mortality? A meta-analysis testing the hypotheses of sex-differential non-specific effects of DTP vaccine. (27856947)
2016
47
Durability of Vaccine-Induced Immunity Against Tetanus and Diphtheria Toxins: A Cross-sectional Analysis. (27161783)
2016
48
Carrier priming effect of CRM197 is related to an enhanced B and T cell activation in meningococcal serogroup A conjugate vaccination. Immunological comparison between CRM197 and diphtheria toxoid. (27015733)
2016
49
State of inequality in diphtheria-tetanus-pertussis immunisation coverage in low-income and middle-income countries: a multicountry study of household health surveys. (27497954)
2016
50
Quadracel: Vaccination Against Diphtheria, Tetanus, Pertussis, and Poliomyelitis in Children. (27069343)
2016

Variations for Diphtheria

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Expression for genes affiliated with Diphtheria

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Search GEO for disease gene expression data for Diphtheria.

Pathways for genes affiliated with Diphtheria

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Pathways related to Diphtheria according to GeneCards Suite gene sharing:

(show all 37)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.7CD9, EEF2, HBEGF
2
Show member pathways
9.6IL13, IL2, IL2RA
39.6IL13, IL2, IL2RA
49.6CSF2, IL13, IL2
59.6CSF2, IL13, IL2
6
Show member pathways
9.5IL2, IL2RA, IL2RB
7
Show member pathways
9.5IL2, IL2RA, IL2RB
8
Show member pathways
9.5IL2, IL2RA, IL2RB
9
Show member pathways
9.4DPH2, DPH3, EEF2
109.2CD9, CSF2, IL2RA, IL3
119.2CSF2, IL2, IL2RA, IL2RB
12
Show member pathways
9.2CSF2, IL2, IL2RA, IL2RB
139.2IL13, IL2, IL2RA, IL2RB
149.2IL13, IL2, IL2RA, IL2RB
15
Show member pathways
9.1IL2, IL2RA, IL2RB, IL3
169.1CD40LG, IL2, IL2RA, IL2RB
17
Show member pathways
9.1CD40LG, IL2, IL2RA, IL2RB
18
Show member pathways
8.9CD40LG, CD79A, CSF2, IL2
19
Show member pathways
8.8CD40LG, CSF2, IL2, IL2RA, IL3
20
Show member pathways
8.8CD79A, CSF2, IL13, IL3
218.8CD79A, EGF, HBEGF
22
Show member pathways
8.8CSF2, IL2, IL2RA, IL2RB, IL3
238.8CD40LG, CSF2, IL13, IL2, IL3
24
Show member pathways
8.3EEF2, EGF, HBEGF, IL2, IL2RA, IL3
258.3EGF, IL2, IL2RA, IL2RB, IL3
268.3EGF, IL2, IL2RA, IL2RB, IL3
278.2CD79A, CSF2, IL2, IL2RA, IL2RB, IL3
288.1CD40LG, CD79A, IL2, IL2RA, IL2RB, IL3
29
Show member pathways
8.0EGF, IL13, IL2, IL2RA, IL2RB, IL3
30
Show member pathways
7.9CD79A, EGF, HBEGF, IL2, IL2RA, IL3
31
Show member pathways
7.8CD79A, EGF, HBEGF, IL2, IL2RA, IL2RB
32
Show member pathways
7.8CSF2, EGF, HBEGF, IL2, IL2RA, IL2RB
33
Show member pathways
7.2CD40LG, CSF2, EGF, IL13, IL2, IL2RA
34
Show member pathways
7.2CD40LG, CSF2, EGF, IL13, IL2, IL2RA
35
Show member pathways
7.0CD40LG, CSF2, EGF, HBEGF, IL13, IL2
36
Show member pathways
7.0CD40LG, CSF2, EGF, HBEGF, IL13, IL2
37
Show member pathways
6.4CD40LG, CD79A, CSF2, EGF, HBEGF, IL13

GO Terms for genes affiliated with Diphtheria

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Cellular components related to Diphtheria according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098978.9CD40LG, CD79A, CD9, IL13, IL2RA, IL2RB
2intracellularGO:00056228.6CD40LG, CSF2, IL2RA, IL2RB, IL3
3extracellular regionGO:00055768.4ALB, CSF2, EGF, HBEGF, IL13, IL2
4extracellular spaceGO:00056157.6ALB, CD40LG, CD9, CSF2, EGF, HBEGF

Biological processes related to Diphtheria according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of lymphocyte proliferationGO:005067210.7IL2, IL2RA
2interleukin-2-mediated signaling pathwayGO:003811010.5IL2RA, IL2RB
3positive regulation of T cell differentiationGO:004558210.5IL2, IL2RA
4peptidyl-diphthamide biosynthetic process from peptidyl-histidineGO:001718310.2DPH2, DPH3, EEF2
5regulation of T cell homeostatic proliferationGO:004601310.0IL2, IL2RA
6positive regulation of T cell proliferationGO:00421029.9CD40LG, IL2, IL2RA
7immune responseGO:00069559.6CSF2, IL13, IL2, IL2RA, IL3
8platelet degranulationGO:00025769.5ALB, CD9, EGF
9positive regulation of tyrosine phosphorylation of Stat5 proteinGO:00425239.5CSF2, IL2, IL3
10peptidyl-tyrosine phosphorylationGO:00181089.5CSF2, EGF, HBEGF, IL3
11positive regulation of cell proliferationGO:00082849.2CSF2, EGF, HBEGF, IL2, IL3
12MAPK cascadeGO:00001658.5CSF2, EGF, HBEGF, IL2, IL2RA, IL2RB
13positive regulation of GTPase activityGO:00435478.3CSF2, EGF, HBEGF, IL2, IL2RA, IL2RB

Molecular functions related to Diphtheria according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1interleukin-2 bindingGO:001997610.4IL2RA, IL2RB
2interleukin-2 receptor activityGO:000491110.4IL2RA, IL2RB
3cytokine activityGO:00051259.4CD40LG, CSF2, IL13, IL2, IL3
4protein tyrosine kinase activityGO:00047139.3CSF2, EGF, HBEGF, IL3
5growth factor activityGO:00080839.1CSF2, EGF, HBEGF, IL2, IL3
6Ras guanyl-nucleotide exchange factor activityGO:00050887.8CSF2, EGF, HBEGF, IL2, IL2RA, IL2RB

Sources for Diphtheria

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet