MCID: DPH003
MIFTS: 34

Diphyllobothriasis malady

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Diphyllobothriasis

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Sources:
10Disease Ontology, 12DISEASES, 51Orphanet, 36MeSH, 2CDC, 65UMLS, 27ICD10, 29ICD9CM, 59SNOMED-CT, 66UMLS via Orphanet, 28ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Diphyllobothriasis:

Name: Diphyllobothriasis 10 12 51 36 2 65
Infection by Bothriocephalus 65
Diphyllobothrium Infection 10
 
Bothriocephalosis 51
Fish Tapeworm 10

Characteristics:

Orphanet epidemiological data:

51
diphyllobothriasis:
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

Disease Ontology10 DOID:10075
ICD1027 B70.0
ICD9CM29 123.4
MeSH36 D004169
Orphanet51 128
UMLS via Orphanet66 C0277032
ICD10 via Orphanet28 B70.0
UMLS65 C0012561, C0277032

Summaries for Diphyllobothriasis

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CDC:2 Diphyllobothrium latum and related species (the fish or broad tapeworm), the largest tapeworms that can infect people, can grow up to 30 feet long. While most infections are asymptomatic, complications include intestinal obstruction and gall bladder disease caused by migration of proglottids. Diagnosis is made by identification of eggs or segments of the tapeworm in a stool sample with a microscope. Safe and effective medications are available to treat Diphyllobothrium. Infections are acquired by eating raw or undercooked fish, usually from the Northern Hemisphere (Europe, newly independent states of the Former Soviet Union, North America, Asia), but cases have also been reported in Uganda and Chile. Fish infected with Diphyllobothrium larvae may be transported to and consumed in any area of the world. Adequately freezing or cooking fish will kill the parasite.

MalaCards based summary: Diphyllobothriasis, also known as infection by bothriocephalus, is related to bothriocephalosis and sparganosis. An important gene associated with Diphyllobothriasis is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I), and among its related pathways is Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. Affiliated tissues include endothelial, smooth muscle and breast.

Disease Ontology:10 A parasitic helminthiasis infectious disease that involves parasitic infection caused by Diphyllobothrium latum through the consumption of raw or undercooked fish. The symptoms include abdominal discomfort, diarrhea, vomiting, weight loss and vitamin B12 deficiency with pernicious anemia.

Wikipedia:68 Diphyllobothriasis is the infection caused by tapeworms of the Diphyllobothrium genus, commonly... more...

Related Diseases for Diphyllobothriasis

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Diseases related to Diphyllobothriasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 66)
idRelated DiseaseScoreTop Affiliating Genes
1bothriocephalosis12.3
2sparganosis11.7
3syphilitic encephalitis10.5MT-CO1, MT-ND3
4mobitz type ii atrioventricular block10.4MT-ATP8, MT-CO1
5mitochondrial encephalomyopathy lactic acidosis and stroke-like episodes10.3MT-ND3, MT-ND5
6protein-losing enteropathy10.3GIF, SCT
7mitochondrial disorders10.3MT-ND3, MT-ND5
8liver disease10.3
9pancreatic ductal adenocarcinoma10.3
10adenocarcinoma10.3
11fatty liver disease10.3
12breast cancer10.3
13prostatitis10.3
14gastrointestinal tuberculosis10.3GAST, GIF
15alcoholic cardiomyopathy10.3MT-ATP8, MT-CO1, MT-ND5
16mitochondrial membrane protein-associated neurodegeneration10.3MT-CO1, MT-ND3, MT-ND5
17gemistocytic astrocytoma10.2MT-ND3, MT-ND5
18infective urethral stricture10.2GAST, SCT
19thymus basaloid carcinoma10.2MT-CO1, MT-ND3, MT-ND5
20dentin sensitivity10.2GAST, SCT
21megaloblastic anemia10.2GAST, GIF
22duodenal disease10.2GAST, SCT
23malignant spiradenoma10.2GAST, SCT
24fibrous synovial sarcoma10.2SERPINA1, TSPO
25prostate cancer10.1
26hepatocellular carcinoma10.1
27asthma10.1
28coronary artery disease10.1
29obesity10.1
30pancreatic cancer10.1
31acute biphenotypic leukemia10.1
32amelogenesis imperfecta10.1
33arthritis10.1
34hepatitis10.1
35leukemia10.1
36chikungunya10.1
37artery disease10.1
38hemorrhagic fever with renal syndrome10.1
39goiter10.1
40nephrocalcinosis10.1
41neuroschistosomiasis10.1
42hypothyroidism10.1
43melanoma10.1
44chondroblastoma10.1
45laryngitis10.1
46pancreatitis10.1
47neuronitis10.1
48eagle syndrome10.1
49hemorrhagic fever10.1
50laryngocele10.1

Graphical network of the top 20 diseases related to Diphyllobothriasis:



Diseases related to diphyllobothriasis

Symptoms for Diphyllobothriasis

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Drugs & Therapeutics for Diphyllobothriasis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Diphyllobothriasis


Cochrane evidence based reviews: diphyllobothriasis

Genetic Tests for Diphyllobothriasis

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Anatomical Context for Diphyllobothriasis

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MalaCards organs/tissues related to Diphyllobothriasis:

33
Endothelial, Smooth muscle, Breast, Liver, Uterus, Monocytes, B cells

Animal Models for Diphyllobothriasis or affiliated genes

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Publications for Diphyllobothriasis

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Articles related to Diphyllobothriasis:

(show all 45)
idTitleAuthorsYear
1
OPRK1 promoter hypermethylation increases the risk of Alzheimer's disease. (26300544)
2015
2
Expression of surfactant protein D in airways of asthmatics and interleukin-13 modulation of surfactant protein D in human models of airway epithelium. (25848896)
2015
3
Inhibition of Proteasome Activity by Low-dose Bortezomib Attenuates Angiotensin II-induced Abdominal Aortic Aneurysm in Apo E(-/-) Mice. (26508670)
2015
4
Bilateral nephrocalcinosis, distal renal tubular acidosis and interstitial nephritis in primary SjAPgren's syndrome. (24962973)
2014
5
Novel I+-synuclein mutation A53E associated with atypical multiple system atrophy and Parkinson's disease-type pathology. (24746362)
2014
6
Dicentric Chromosome 14;18 Plus Two Additional CNVs in a Girl with Microform Holoprosencephaly and Turner Stigmata. (24778566)
2013
7
Potential of tumor-suppressive miR-596 targeting LGALS3BP as a therapeutic agent in oral cancer. (23233740)
2013
8
Prenatal diagnosis of partial trisomy 3q (3q27.3a89qter) and partial monosomy 14q (14q31.3a89qter) of paternal origin associated with fetal hypotonia, arthrogryposis, scoliosis and hyperextensible joints. (23266805)
2013
9
Macrophage activation syndrome in children with systemic onset juvenile idiopathic arthritis: clinical experience from northwest India. (21221591)
2012
10
Familial renal cancer as an indicator of hereditary leiomyomatosis and renal cell cancer syndrome. (22127509)
2012
11
Polycystic liver disease presenting with an exudative pleural effusion: a case report. (22502729)
2012
12
Ventricular candidiasis in stone curlews (Burhinus oedicnemus). (22017057)
2011
13
Thymic extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue: a clinicopathological and genetic analysis of six cases. (21745165)
2011
14
Biometric analysis of pigment dispersion syndrome using anterior segment optical coherence tomography. (21531465)
2011
15
Origin and evolution of ubiquitin-conjugating enzymes from Guillardia theta nucleomorph to hominoid. (19664694)
2009
16
Expression of the V264M TFPI mutant in endothelial cell cultures may involve mRNA stability. (19007969)
2009
17
Newer therapeutic options for chronic inflammatory demyelinating polyradiculoneuropathy. (19496628)
2009
18
Humidified air for croup? (17225704)
2007
19
Functional promiscuity correlates with conformational heterogeneity in A-class glutathione S-transferases. (17561509)
2007
20
Functional expression of the globular domain of human adiponectin in Pichia pastoris. (17900532)
2007
21
Myotonia-related mutations in the distal C-terminus of ClC-1 and ClC-0 chloride channels affect the structure of a poly-proline helix. (17107341)
2007
22
Tissue distribution and functional analyses of the constitutively active orphan G protein coupled receptors, GPR26 and GPR78. (17363172)
2007
23
Expression of receptor activator of nuclear factor kappabeta ligand (RANKL) and tumour necrosis factor related, apoptosis inducing ligand (TRAIL) in breast cancer, and their relations with osteoprotegerin, oestrogen receptor, and clinicopathological variables. (16489180)
2006
24
Heparin-immobilized biodegradable scaffolds for local and sustained release of angiogenic growth factor. (16941589)
2006
25
HSulf-1 inhibits angiogenesis and tumorigenesis in vivo. (16778174)
2006
26
IFN-alpha sensitizes human umbilical vein endothelial cells to apoptosis induced by double-stranded RNA. (14734752)
2004
27
Frontotemporal dementia/Pick's disease. (15210543)
2004
28
Abundant retention and release of connective tissue growth factor (CTGF/CCN2) by platelets. (15598883)
2004
29
Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria. (12678693)
2003
30
Herpesviral protein targets a cellular WD repeat endosomal protein to downregulate T lymphocyte receptor expression. (12196293)
2002
31
Motoneuron-specific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner. (11717388)
2001
32
Scimitar syndrome: diagnosis with MR angiography. (10350327)
1999
33
Opioid peptides in response to mental stress in asymptomatic dilated cardiomyopathy. (9786163)
1998
34
Free pentosidine and neopterin as markers of progression rate in diabetic nephropathy. Collaborative Study Group. (9648079)
1998
35
Transcriptional activation of the minimal human Proalpha1(I) collagen promoter: obligatory requirement for Sp1. (9173885)
1997
36
Adenosarcoma of the uterus with extensive smooth muscle differentiation: ultrastructural study and review of the literature. (9029768)
1997
37
Osteochondritis dissecans of the talus presenting as an ankle ganglion. (9127870)
1997
38
Helicobacter pylori, a rediscovered bacterium. Implication in gastroduodenal diseases]. (7899350)
1995
39
Polymer IgM assembly and secretion in lymphoid and nonlymphoid cell lines: evidence that J chain is required for pentamer IgM synthesis. (7708742)
1995
40
Genomic organization and chromosomal localization of the human and mouse genes encoding the alpha receptor component for ciliary neurotrophic factor. (7774913)
1995
41
Topical calcipotriol in the treatment of epidermolytic palmoplantar keratoderma of VAPrner. (8186131)
1994
42
Familial true hermaphroditism: paternal and maternal transmission of true hermaphroditism (46,XX) and XX maleness in the absence of Y-chromosomal sequences. (8262517)
1993
43
Regulation of human monocyte DNA synthesis by colony-stimulating factors, cytokines, and cyclic adenosine monophosphate. (1314111)
1992
44
Arteriosclerosis obliterans in the lower extremities: correlation of clinical and angiographic findings. (5119840)
1971
45
Lethal midline granuloma-Wegener's granulomatosis. (13917045)
1961

Variations for Diphyllobothriasis

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Expression for genes affiliated with Diphyllobothriasis

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Search GEO for disease gene expression data for Diphyllobothriasis.

Pathways for genes affiliated with Diphyllobothriasis

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GO Terms for genes affiliated with Diphyllobothriasis

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Cellular components related to Diphyllobothriasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055768.9GAST, GIF, SCT, SERPINA1

Biological processes related to Diphyllobothriasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial electron transport, NADH to ubiquinoneGO:000612010.3MT-ND3, MT-ND5
2heart loopingGO:00019479.9DLL1, NOTO
3determination of left/right symmetryGO:00073689.9DLL1, NOTO
4oxidation-reduction processGO:00551149.7MT-CO1, MT-ND3, MT-ND5

Molecular functions related to Diphyllobothriasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ATPase activityGO:00168879.8DNAH8, MT-ATP8

Sources for Diphyllobothriasis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet