MCID: DRF001
MIFTS: 28

Dirofilariasis malady

Rare diseases, Infectious diseases categories

Summaries for Dirofilariasis

About this section


CDC:3 Dirofilariasis in humans is caused by Dirofilaria roundworms. The main natural hosts for the three Dirofilaria species that most frequently cause disease in humans are dogs and wild canids (such as wolves and foxes) and raccoons. Humans are infected with Dirofilaria larvae through mosquito bites. Infection can result in nodules under the skin or conjunctiva and lung granulomas (small nodules formed by an inflammatory reaction) that appear as coin lesions (small, round abnormalities) on x-rays, leading to diagnostic procedures to exclude more serious diseases.

MalaCards based summary: Dirofilariasis, also known as dirofilaria infectious disease, is related to lung cancer and hepatitis. An important gene associated with Dirofilariasis is NSUN2 (NOP2/Sun RNA methyltransferase family, member 2). Affiliated tissues include lung, skin and breast.

Disease Ontology:9 A filariasis that is a zoonotic infection caused by nematodes dirofilaria immitis or dirofilaria repens, which are transmitted to humans from dogs, cats, wolves and coyotes by infected mosquitoes. the disease manifests as either subcutaneous nodules or pulmonary lesions.

Wikipedia:63 Dirofilariasis is an infection by parasites in the Dirofilaria genus. more...

Aliases & Classifications for Dirofilariasis

About this section
Sources:
9Disease Ontology, 41NIH Rare Diseases, 11DISEASES, 47Orphanet, 3CDC, 60UMLS, 55SNOMED-CT, 33MeSH, 34MESH via Orphanet, 26ICD10 via Orphanet, 61UMLS via Orphanet
See all sources

Dirofilariasis, Aliases & Descriptions:

Name: Dirofilariasis 9 41 11 47 3 60
Dirofilaria Infectious Disease 9
 
Infection by Dirofilaria 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases


Characteristics (Orphanet epidemiological data):

47
dirofilariasis:
Inheritance: Not applicable; Age of onset: All ages


External Ids:

Disease Ontology9 DOID:1082
MeSH33 D004184
Orphanet47 166291
SNOMED-CT55 73328005
MESH via Orphanet34 D004184
ICD10 via Orphanet26 B74.8
UMLS via Orphanet61 C0012602

Related Diseases for Dirofilariasis

About this section

Diseases related to Dirofilariasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
idRelated DiseaseScoreTop Affiliating Genes
1lung cancer10.1
2hepatitis10.1
3langerhans-cell histiocytosis10.1
4eosinophilia10.1
5histiocytosis10.1
6meningitis10.1
7breast cancer10.0
8pulmonary hypertension10.0
9arthritis10.0
10congestive heart failure10.0
11onchocerciasis10.0
12reactive arthritis10.0
13eosinophilic meningitis10.0
14pulmonary coin lesion10.0
15fascioliasis10.0
16toxocariasis10.0
17arteriosclerosis10.0
18filariasis10.0
19mediastinitis10.0
20neurilemmoma10.0
21pneumothorax10.0
22scleritis10.0
23transitional cell carcinoma10.0
24pandas10.0
25proteinuria10.0

Graphical network of the top 20 diseases related to Dirofilariasis:



Diseases related to dirofilariasis

Symptoms for Dirofilariasis

About this section

Drugs & Therapeutics for Dirofilariasis

About this section

Drug clinical trials:

Search ClinicalTrials for Dirofilariasis

Search NIH Clinical Center for Dirofilariasis

Genetic Tests for Dirofilariasis

About this section

Anatomical Context for Dirofilariasis

About this section

MalaCards organs/tissues related to Dirofilariasis:

31
Lung, Skin, Breast, Testes, Eye, Heart, B cells

Animal Models for Dirofilariasis or affiliated genes

About this section

Publications for Dirofilariasis

About this section

Articles related to Dirofilariasis:

(show top 50)    (show all 364)
idTitleAuthorsYear
1
Comments in response to the authors of "Human dirofilariasis due to Dirofilaria repens in the Russian Federation-remarks concerning epidemiology". (24923661)
2014
2
Subconjunctival dirofilariasis: Case studies with review of literature. (25250234)
2014
3
Oral dirofilariasis. (24992859)
2014
4
Dirofilariasis of the breast: sonographic appearance. (24615752)
2014
5
Periocular dirofilariasis mimicking lacrimal sac mucocoele. (23895409)
2013
6
Subcutaneous dirofilariasis. (23023910)
2012
7
Intradural dirofilariasis mimicking a Langerhans cell histiocytosis tumor. (19489058)
2009
8
Canine and feline dirofilariasis. (19086252)
2008
9
Ocular dirofilariasis in Dubai, UAE. (18579995)
2008
10
Dirofilariasis in Argentina: historical review and first report of Dirofilaria immitis in a natural mosquito population. (16310953)
2006
11
Human pulmonary dirofilariasis: a case report and review of the recent Japanese literature. (16635097)
2006
12
Subcutaneous dirofilariasis caused by Dirofilaria immitis mimicking a large epidermal cyst. (16643162)
2006
13
A case of periocular dirofilariasis masquerading as a lid tumour. (15829752)
2005
14
Unusual finding in a nipple discharge of a female dog: dirofilariasis of the breast. (15637669)
2005
15
Human dirofilariasis of the buccal mucosa: a case report. (12653245)
2003
16
Prevalence of canine dirofilariasis in Taiwan. (12590670)
2003
17
Immunoglobulin G antibodies against the endosymbionts of filarial nematodes (Wolbachia) in patients with pulmonary dirofilariasis. (12522059)
2003
18
Human dirofilariasis in Costa Rica: Dirofilaria immitis in periorbital tissues. (12669355)
2003
19
Subconjunctival dirofilariasis in India. (11556571)
2001
20
Pulmonary dirofilariasis in a patient with multisystem Langerhans cell histiocytosis--the first reported case in Thailand. (9737133)
1998
21
The first case report of suspected human dirofilariasis in the eyelid of a patient from Alexandria. (9914714)
1998
22
Description of the occurrence of canine dirofilariasis in the State of Rio de Janeiro, Brazil. (9302414)
1997
23
Subcutaneous dirofilariasis in Collier County, Florida, USA. (7611540)
1995
24
Pulmonary dirofilariasis in man: a new Italian case. Review of the European literature. (9140502)
1994
25
Conjunctival dirofilariasis in British Columbia. (8313223)
1993
26
Feline dirofilariasis. (8421884)
1993
27
Salivary mucocele associated with dirofilariasis in a dog. (1639703)
1992
28
Chylothorax associated with dirofilariasis in a cat. (2211298)
1990
29
Dirofilariasis of the breast. (2566753)
1989
30
Pulmonary dirofilariasis. The largest single-institution experience. (2915565)
1989
31
Human pulmonary dirofilariasis: does diagnosis require thoracotomy? (3355289)
1988
32
Human pulmonary dirofilariasis. (3384627)
1988
33
Clinical effects after heartworm removal from pulmonary arteries using flexible alligator forceps in dogs with common dirofilariasis. (3210484)
1988
34
Lipids in serum, lipoproteins and erythrocyte membranes in canine dirofilariasis by TLC-FID method. (3586455)
1987
35
Dirofilariasis presenting as a breast lump (correction) (6498666)
1984
36
Dirofilariasis with arteriosclerosis in a horse. (6480468)
1984
37
Dirofilariasis in a ferret. (7085481)
1982
38
Human subcutaneous dirofilariasis. 1. Two new cases in Venice. Identification of the causal agent as Dirofilaria repens Raillet and Henry, 1911. (6926932)
1982
39
Dirofilariasis. IV. Glomerulonephropathy induced by Dirofilaria immitis infection. (6452068)
1981
40
Dirofilariasis of the breast in france. (7435780)
1980
41
Human subcutaneous dirofilariasis in Illinois. (660850)
1978
42
Electrophoretical studies on serum lipoprotein fractions in canine dirofilariasis. (916460)
1977
43
Experimental dirofilariasis in macaques. III. Susceptibility and host responses to Dirofilaria tenuis of raccoons. (816216)
1976
44
Letter: Human pulmonary dirofilariasis: entry method of infective larvae. (238798)
1975
45
Experimental occult dirofilariasis in dogs with reference to immunological responses and its relationship to tropical eosinophilia in man. (4617308)
1974
46
Ruptured pulmonary artery in a dog with dirofilariasis. (4721753)
1973
47
Human pulmonary dirofilariasis. (5110572)
1971
48
Dirofilariasis-- an emerging zoonosis? (5389194)
1969
49
Feline dirofilariasis in Papula. (6007745)
1966
50
Canine dirofilariasis. II. Utilization of a rapid film change technique. (14398841)
1960

Variations for Dirofilariasis

About this section

Expression for genes affiliated with Dirofilariasis

About this section
Search GEO for disease gene expression data for Dirofilariasis.

Pathways for genes affiliated with Dirofilariasis

About this section

Compounds for genes affiliated with Dirofilariasis

About this section

GO Terms for genes affiliated with Dirofilariasis

About this section

Products for genes affiliated with Dirofilariasis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Dirofilariasis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet