MCID: DRF001
MIFTS: 33

Dirofilariasis malady

Rare diseases, Infectious diseases categories
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Summaries for Dirofilariasis

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CDC:3 Dirofilariasis in humans is caused by Dirofilaria roundworms. The main natural hosts for the three Dirofilaria species that most frequently cause disease in humans are dogs and wild canids (such as wolves and foxes) and raccoons. Humans are infected with Dirofilaria larvae through mosquito bites. Infection can result in nodules under the skin or conjunctiva and lung granulomas (small nodules formed by an inflammatory reaction) that appear as coin lesions (small, round abnormalities) on x-rays, leading to diagnostic procedures to exclude more serious diseases.

MalaCards based summary: Dirofilariasis, also known as infection by dirofilaria, is related to hepatitis and langerhans-cell histiocytosis. An important gene associated with Dirofilariasis is NSUN2 (NOP2/Sun RNA methyltransferase family, member 2). Affiliated tissues include lung, skin and breast.

Disease Ontology:8 A filariasis that is a zoonotic infection caused by nematodes dirofilaria immitis or dirofilaria repens, which are transmitted to humans from dogs, cats, wolves and coyotes by infected mosquitoes. the disease manifests as either subcutaneous nodules or pulmonary lesions.

Wikipedia:65 Dirofilariasis is an infection by parasites in the Dirofilaria genus. more...

Aliases & Classifications for Dirofilariasis

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 48Orphanet, 62UMLS, 57SNOMED-CT, 34MeSH, 35MESH via Orphanet, 26ICD10 via Orphanet, 63UMLS via Orphanet
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Dirofilariasis, Aliases & Descriptions:

Name: Dirofilariasis 8 42 10 48 62
Infection by Dirofilaria 8 62
 
Dirofilaria Infectious Disease 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases


Characteristics (Orphanet epidemiological data):

48
dirofilariasis:
Prevalence: <1/1000000; Age of onset: Neonatal/infancy


External Ids:

Disease Ontology8 DOID:1082
MeSH34 D004184
MESH via Orphanet35 D004184
SNOMED-CT57 73328005
ICD10 via Orphanet26 B74.8
UMLS via Orphanet63 C0012602

Related Diseases for Dirofilariasis

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Diseases related to Dirofilariasis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 26)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis10.1
2langerhans-cell histiocytosis10.1
3eosinophilia10.1
4histiocytosis10.1
5lung cancer10.1
6meningitis10.1
7thromboembolism10.1
8arthritis10.0
9congestive heart failure10.0
10hypertension10.0
11pulmonary hypertension10.0
12reactive arthritis10.0
13fascioliasis10.0
14pulmonary coin lesion10.0
15toxocariasis10.0
16eosinophilic meningitis10.0
17arteriosclerosis10.0
18breast cancer10.0
19mediastinitis10.0
20neurilemmoma10.0
21osteosarcoma10.0
22pneumothorax10.0
23proteinuria10.0
24scleritis10.0
25transitional cell carcinoma10.0
26pandas10.0

Graphical network of the top 20 diseases related to Dirofilariasis:



Diseases related to dirofilariasis

Symptoms for Dirofilariasis

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Drugs & Therapeutics for Dirofilariasis

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Drug clinical trials:

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Genetic Tests for Dirofilariasis

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Anatomical Context for Dirofilariasis

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MalaCards organs/tissues related to Dirofilariasis:

32
Lung, Skin, Breast, Testes, Eye, Heart, B cells

Animal Models for Dirofilariasis or affiliated genes

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Publications for Dirofilariasis

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Articles related to Dirofilariasis:

(show top 50)    (show all 353)
idTitleAuthorsYear
1
Comments in response to the authors of &quot;Human dirofilariasis due to Dirofilaria repens in the Russian Federation-remarks concerning epidemiology&quot;. (24923661)
2014
2
Subconjunctival dirofilariasis: Case studies with review of literature. (25250234)
2014
3
Oral dirofilariasis. (24992859)
2014
4
Dirofilariasis of the breast: sonographic appearance. (24615752)
2014
5
Periocular dirofilariasis mimicking lacrimal sac mucocoele. (23895409)
2013
6
Subcutaneous dirofilariasis. (23023910)
2012
7
Intradural dirofilariasis mimicking a Langerhans cell histiocytosis tumor. (19489058)
2009
8
Canine and feline dirofilariasis. (19086252)
2008
9
Ocular dirofilariasis in Dubai, UAE. (18579995)
2008
10
Survey of canine dirofilariasis in Vojvodina, Serbia. (18712415)
2008
11
Dirofilariasis in Argentina: historical review and first report of Dirofilaria immitis in a natural mosquito population. (16310953)
2006
12
Human pulmonary dirofilariasis: a case report and review of the recent Japanese literature. (16635097)
2006
13
Subcutaneous dirofilariasis caused by Dirofilaria immitis mimicking a large epidermal cyst. (16643162)
2006
14
Unusual finding in a nipple discharge of a female dog: dirofilariasis of the breast. (15637669)
2005
15
Human dirofilariasis of the buccal mucosa: a case report. (12653245)
2003
16
Prevalence of canine dirofilariasis in Taiwan. (12590670)
2003
17
Immunoglobulin G antibodies against the endosymbionts of filarial nematodes (Wolbachia) in patients with pulmonary dirofilariasis. (12522059)
2003
18
Human dirofilariasis in Costa Rica: Dirofilaria immitis in periorbital tissues. (12669355)
2003
19
Subconjunctival dirofilariasis in India. (11556571)
2001
20
Pulmonary dirofilariasis in a patient with multisystem Langerhans cell histiocytosis--the first reported case in Thailand. (9737133)
1998
21
The first case report of suspected human dirofilariasis in the eyelid of a patient from Alexandria. (9914714)
1998
22
Description of the occurrence of canine dirofilariasis in the State of Rio de Janeiro, Brazil. (9302414)
1997
23
Subcutaneous dirofilariasis in Collier County, Florida, USA. (7611540)
1995
24
Pulmonary dirofilariasis in man: a new Italian case. Review of the European literature. (9140502)
1994
25
Conjunctival dirofilariasis in British Columbia. (8313223)
1993
26
Feline dirofilariasis. (8421884)
1993
27
Salivary mucocele associated with dirofilariasis in a dog. (1639703)
1992
28
Chylothorax associated with dirofilariasis in a cat. (2211298)
1990
29
Dirofilariasis of the breast. (2566753)
1989
30
Pulmonary dirofilariasis. The largest single-institution experience. (2915565)
1989
31
Human pulmonary dirofilariasis: does diagnosis require thoracotomy? (3355289)
1988
32
Human pulmonary dirofilariasis. (3384627)
1988
33
Clinical effects after heartworm removal from pulmonary arteries using flexible alligator forceps in dogs with common dirofilariasis. (3210484)
1988
34
Lipids in serum, lipoproteins and erythrocyte membranes in canine dirofilariasis by TLC-FID method. (3586455)
1987
35
Dirofilariasis presenting as a breast lump (correction) (6498666)
1984
36
Dirofilariasis with arteriosclerosis in a horse. (6480468)
1984
37
Dirofilariasis in a ferret. (7085481)
1982
38
Human subcutaneous dirofilariasis. 1. Two new cases in Venice. Identification of the causal agent as Dirofilaria repens Raillet and Henry, 1911. (6926932)
1982
39
Dirofilariasis. IV. Glomerulonephropathy induced by Dirofilaria immitis infection. (6452068)
1981
40
Dirofilariasis of the breast in france. (7435780)
1980
41
Human subcutaneous dirofilariasis in Illinois. (660850)
1978
42
Electrophoretical studies on serum lipoprotein fractions in canine dirofilariasis. (916460)
1977
43
Experimental dirofilariasis in macaques. III. Susceptibility and host responses to Dirofilaria tenuis of raccoons. (816216)
1976
44
Letter: Human pulmonary dirofilariasis: entry method of infective larvae. (238798)
1975
45
Experimental occult dirofilariasis in dogs with reference to immunological responses and its relationship to tropical eosinophilia in man. (4617308)
1974
46
Ruptured pulmonary artery in a dog with dirofilariasis. (4721753)
1973
47
Human pulmonary dirofilariasis. (5110572)
1971
48
Dirofilariasis-- an emerging zoonosis? (5389194)
1969
49
Feline dirofilariasis in Papula. (6007745)
1966
50
Canine dirofilariasis. II. Utilization of a rapid film change technique. (14398841)
1960

Variations for Dirofilariasis

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Expression for genes affiliated with Dirofilariasis

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Expression patterns in normal tissues for genes affiliated with Dirofilariasis

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Pathways for genes affiliated with Dirofilariasis

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Compounds for genes affiliated with Dirofilariasis

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GO Terms for genes affiliated with Dirofilariasis

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Products for genes affiliated with Dirofilariasis

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Sources for Dirofilariasis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet