Categories: Rare diseases, Infectious diseases, Skin diseases
Aliases & Descriptions for Dirofilariasis:
Orphanet epidemiological data:52
Inheritance: Not applicable; Age of onset: All ages
Global: Rare diseases, Infectious diseases
Anatomical: Skin diseases
Rare infectious diseases
NIH Rare Diseases:46 Dirofilariasis refers to infections caused by dirofilaria roundworms. although the natural hosts of these roundworms are dogs, wild canids (such as wolves and foxes) and raccoons, humans can be infected with dirofilaria larvae through mosquito bites. signs and symptoms of dirofilariasis generally include nodules under the skin or lung granulomas (small nodules formed by an inflammatory reaction) which may be asymptomatic. some people with dirofilariasis of the lungs may also experience cough, chest pain, fever, wheezing, chills, and pleural effusion (excess fluid between the tissues that line the lungs and the chest cavity). dirofilariasis is treated with surgical removal of lung granulomas and skin nodules. last updated: 4/27/2016
MalaCards based summary: Dirofilariasis, also known as dirofilaria infectious disease, is related to toxocariasis and discharging ear. An important gene associated with Dirofilariasis is UBASH3A (Ubiquitin Associated And SH3 Domain Containing A), and among its related pathways are Effects of nitric oxide and A-beta Pathways: Plaque Formation and APP Metabolism. Affiliated tissues include lung, skin and breast, and related mouse phenotypes are cellular and cardiovascular system.
Disease Ontology:11 A filariasis that is a zoonotic infection caused by nematodes dirofilaria immitis or dirofilaria repens, which are transmitted to humans from dogs, cats, wolves and coyotes by infected mosquitoes. the disease manifests as either subcutaneous nodules or pulmonary lesions.
CDC:2 Dirofilariasis in humans is caused by Dirofilaria roundworms. The main natural hosts for the three Dirofilaria species that most frequently cause disease in humans are dogs and wild canids (such as wolves and foxes) and raccoons. Humans are infected with Dirofilaria larvae through mosquito bites. Infection can result in nodules under the skin or conjunctiva and lung granulomas (small nodules formed by an inflammatory reaction) that appear as coin lesions (small, round abnormalities) on x-rays, leading to diagnostic procedures to exclude more serious diseases.
Wikipedia:69 Dirofilariasis is an infection by parasites in the Dirofilaria genus. more...
MalaCards organs/tissues related to Dirofilariasis:34
Lung, Skin, Breast, Testes, B cells, Heart, Eye
Articles related to Dirofilariasis:(show top 50) (show all 400)
Search GEO for disease gene expression data for Dirofilariasis.
Pathways related to Dirofilariasis according to GeneCards Suite gene sharing:
Cellular components related to Dirofilariasis according to GeneCards Suite gene sharing:
Biological processes related to Dirofilariasis according to GeneCards Suite gene sharing:
29ICD10 via Orphanet
38MESH via Orphanet
51OMIM via Orphanet
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
67UMLS via Orphanet