MCID: DSS009
MIFTS: 48

Disseminated Intravascular Coagulation malady

Immune diseases, Blood diseases categories

Aliases & Classifications for Disseminated Intravascular Coagulation

About this section
Sources:
10Disease Ontology, 47Novoseek, 12DISEASES, 65UMLS, 36MeSH, 29ICD9CM, 59SNOMED-CT, 42NCIt, 27ICD10
See all sources

Aliases & Descriptions for Disseminated Intravascular Coagulation:

Name: Disseminated Intravascular Coagulation 10 47 12 65 36
Defibrination Syndrome 10
 
Diffuse 10
Dic 10


Classifications:



External Ids:

Disease Ontology10 DOID:11247
ICD9CM29 286.6
MeSH36 D004211
SNOMED-CT59 267563002, 67406007
NCIt42 C2992
ICD1027 D65

Summaries for Disseminated Intravascular Coagulation

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Wikipedia:68 Disseminated intravascular coagulation (DIC), also known as disseminated intravascular coagulopathy or... more...

MalaCards based summary: Disseminated Intravascular Coagulation, also known as defibrination syndrome, is related to thrombotic thrombocytopenic purpura and dic in newborn. An important gene associated with Disseminated Intravascular Coagulation is SERPINC1 (Serpin Peptidase Inhibitor, Clade C (Antithrombin), Member 1), and among its related pathways are Warfarin Pathway, Pharmacodynamics and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). The drugs antithrombin iii, human and antithrombin iii,recombinant have been mentioned in the context of this disorder. Affiliated tissues include liver, bone and prostate, and related mouse phenotypes are normal and respiratory system.

Related Diseases for Disseminated Intravascular Coagulation

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Diseases related to Disseminated Intravascular Coagulation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 384)
idRelated DiseaseScoreTop Affiliating Genes
1thrombotic thrombocytopenic purpura31.0FN1, PLG
2dic in newborn30.9F2, F3
3protein c deficiency30.9F2, F5, SERPINC1
4liver disease30.7F2, SERPINC1, SERPINF2
5factor x deficiency30.6F2, F3, F5, F9
6systemic lupus erythematosus30.6ADAMTS13, ELANE, F2, F3, THBD
7pure red-cell aplasia30.4FN1, PLG
8malaria30.4ADAMTS13, ELANE, F3, PROCR, THBD
9vascular hemostatic disease30.1F3, F5, FGA, PLAT, PLG, SERPINC1
10thymic carcinoma30.0F2, F5, PLAT, SERPINC1, SERPINE1, SERPINF2
11thrombophlebitis29.1F2, F3, F5, F9, PROCR, SERPINC1
12myocardial infarction28.0ADAMTS13, F2, F3, F5, F9, FGA
13leukemia10.9
14aneurysm10.9
15purpura10.8
16prostatitis10.8
17aortic aneurysm10.7
18prostate cancer10.7
19gastric cancer10.7
20hepatitis10.7
21thrombocytopenia10.7
22pancreatitis10.7
23meningococcemia10.7
24liver cirrhosis10.6
25endocarditis10.6
26pneumonia10.6
27adult-onset still's disease10.6
28endotheliitis10.6
29acute leukemia10.6
30hemolytic anemia10.6
31placental abruption10.6
32cerebritis10.6
33adenocarcinoma10.6
34blood coagulation disease10.6
35pulmonary embolism10.6
36thrombophilia10.6
37tuberculosis10.6
38factor v leiden thrombophilia10.6
39meningococcal infection10.6
40pancreatic cancer10.5
41protein s deficiency10.5
42abdominal aortic aneurysm10.5
43lupus erythematosus10.5
44thyroiditis10.5
45bone marrow necrosis10.5
46hemorrhagic fever10.5
47osteonecrosis10.4
48ulcerative colitis10.4
49scrub typhus10.4
50acute pancreatitis10.4

Graphical network of the top 20 diseases related to Disseminated Intravascular Coagulation:



Diseases related to disseminated intravascular coagulation

Symptoms for Disseminated Intravascular Coagulation

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Drugs & Therapeutics for Disseminated Intravascular Coagulation

About this section

Drugs for Disseminated Intravascular Coagulation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Tranexamic AcidapprovedPhase 41991197-18-85526
Synonyms:
08455_FLUKA
1197-17-7
1197-18-8
1ceb
3-14-00-00868 (Beilstein Handbook Reference)
4-(Aminomethyl)-Cyclohexanecarboxylic Acid
4-(Aminomethyl)cyclohexanecarboxylic acid
4-(aminomethyl)cyclohexane-1-carboxylic acid
857653_ALDRICH
A0236
AB00052260
AB1003647
AC-4687
AC1L1KJH
AC1Q50F3
AC1Q546D
AC1Q5U04
ALBB-006013
AMCA
AMCHA
AMH
AR-1F6595
Acide tranexamique
Acide tranexamique [INN-French]
Acido tranexamico
Acido tranexamico [INN-Spanish]
Acidum tranexamicum
Acidum tranexamicum [INN-Latin]
Amikapron
Amstat
Anvitoff
BAY 3517
BPBio1_000069
BRN 2207452
BSPBio_000061
BSPBio_002837
CAS-1197-18-8
CHEBI:48669
CHEMBL292500
CHEMBL877
CID5526
CL 65336
CL-65336
Carxamin
Cyclocapron
Cyklokapron
Cyklokapron (TN)
D01136
DB00302
DV 79
DV-79
DV79
DivK1c_000655
EINECS 214-818-2
Emorhalt
Exacyl
Frenolyse
HMS1568D03
HMS1921F08
HMS2092P03
HMS502A17
Hexapromin
Hexatron
I04-0993
IDI1_000655
KABI 2161
KBio1_000655
KBio2_001871
KBio2_004439
KBio2_007007
KBio3_002337
KBioGR_000511
KBioSS_001871
 
LS-56611
LS-56612
LT00159441
Lysteda
Mastop
MolPort-001-792-390
MolPort-002-512-008
NCGC00016569-01
NCGC00016569-02
NCGC00016569-03
NCGC00094944-01
NCGC00094944-02
NINDS_000655
NSC 291305
NSC291305
Oprea1_786414
Prestwick0_000171
Prestwick1_000171
Prestwick2_000171
Prestwick3_000171
Prestwick_476
RP 18,429
Rikavarin
Rikavarin (TN)
Rikavarin-S
SPBio_000689
SPBio_001982
SPECTRUM1502026
STK503668
STOCK1N-16183
Spectrum2_000655
Spectrum3_001189
Spectrum4_000046
Spectrum5_001258
Spectrum_001391
Spiramin
Tamcha
Tranex
Tranexamate
Tranexamic Acid
Tranexamic acid (JP15/USAN/INN)
Tranexamic acid [USAN:INN:BAN:JAN]
Tranexamic acid cis-form
Tranexamsaeure
Tranexan
Tranexmic acid
Tranhexamic acid
Trans AMCHA
Trans-1-(Aminomethyl)cyclohexane-4-carboxylic acid
Trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid
Trans-p-(Aminomethyl)cyclohexanecarboxylic
Transamin
Transamin (TN)
Transamlon
Trasamlon
UNII-6T84R30KC1
Ugurol
WLN: L6TJ AVQ D1Z -T
cis-4-(Aminomethyl)cyclohexanecarboxylic acid
cis-4-Aminomethylcyclohexane-1-carboxylic acid
cis-AMCHA
t-AMCHA
tranexamic acid
tranexmic acid
trans-1-Aminomethylcyclohexane-4-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-carboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid ester
trans-4-Aminomethylcyclohexane-1-carboxylic acid
trans-4-aminomethylcyclohexane-1-carboxylic acid
trans-Amcha
trans-Tranexamic acid
trans-p-(Aminomethyl)cyclohexanecarboxylic acid
2
PrasugrelapprovedPhase 4160150322-43-36918456
Synonyms:
CS-747
Effient
Efient
 
Prasita
Prasugrel
Prasugrel Hydrochloride
SID124899264
cs-747
3
Magnesium SulfateapprovedPhase 41437487-88-924083
Synonyms:
(C10-C16) Alkylalcohol sulfuric acid, magnesium salt
00627_FLUKA
10028-26-9
10034-99-8 (heptahydrate)
13143_RIEDEL
13143_SIAL
139939-75-6
18939-43-0
203726_ALDRICH
208094_SIAL
34276_FLUKA
34276_RIEDEL
38146_FLUKA
38146_RIEDEL
63126_FLUKA
63136_FLUKA
63136_SIAL
63139_FLUKA
63139_SIAL
68081-97-0
7487-88-9
AC1L2N76
AC1LAX36
AC1Q1U66
AI3-02029
Bitter salt
C10-C16 Alkyl alcohol sulfuric acid magnesium salt
CCRIS 8411
CHEBI:32599
CID24083
CPD0-2390
Caswell No. 534
D008278
DB00653
EINECS 231-298-2
EINECS 233-073-4
EINECS 242-691-3
EINECS 268-365-0
EPA Pesticide Chemical Code 050503
Epsom Sal
Epsom Salt
Epsom Salt Magnesium Sulfate
Epsom Salt Soaking Solution
Epsom salt
HSDB 664
Hair salt
Health Smart Natural Epsom Salt
Heptahydrate Magnesium Sulfate
Humco Epson Salt
Kieserite [as monohydrate]
LS-88605
M2643_SIGMA
M3409_SIGMA
 
M7506_SIAL
M8150_SIGMA
MAGNESIUM SULFATE
Magnesium Sulfate
Magnesium Sulfate In Plastic Container
Magnesium Sulfate, Heptahydrate
Magnesium Sulphate Hydrate
Magnesium bisulfate
Magnesium hydrogensulphate
Magnesium sulfate
Magnesium sulfate (1:1)
Magnesium sulfate anhydrous
Magnesium sulfate dried
Magnesium sulfate heptahydrate
Magnesium sulfate hexahydrate
Magnesium sulfate in dextrose 5% in plastic container
Magnesium sulfate solution
Magnesium sulphate
Magnesium sulphate anhydrous
Magnesium sulphate dried
Magnesium sulphate heptahydrate
Magnesium(II) sulfate
Magnesium(ii) sulfate
Magnesiumsulfat
MgSO4
MolPort-003-925-000
Morton Natural Epsom Salt
NSC 146179
Natural Epsom Salt
OT-S
OT-S (drying agent)
Pepsom Flying P Epsom Salt
Pepsom Salt Peppermint
Royal Epsom Salt
SDA 15-062-07
Sal Angalis
Sal De sedlitz
Sal amarum
Sal anglicum
Sal catharticum
Sal seidlitense
Salts of england
Sel d'angleterre
Sulfate, Magnesium
Sulfuric acid magnesium salt
Sulfuric acid magnesium salt (1:1)
Sulfuric acid magnesium salt (VAN)
Sulfuric acid, C10-16 alkyl ester, magnesium salt
Sulfuric acid, magnesium salt
Sulfuric acid, magnesium salt (1:1)
Sulfuric acid, mono-C10-16-alkyl esters, magnesium salts
Tomix OT
UNII-DE08037SAB
UNII-ML30MJ2U7I
magnesium(2+) ion sulfate
4Calcium, DietaryPhase 4, Phase 33529
5ThrombinPhase 4257
6ThromboplastinPhase 453
7Factor VIIIPhase 4265
8CoagulantsPhase 4983
9
Heparinapproved, investigationalPhase 36729005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
10calcium heparinPhase 3672
11AntithrombinsPhase 3, Phase 2268
12Antithrombin IIIPhase 3, Phase 2259
13UrinastatinPhase 2, Phase 312
14serineNutraceuticalPhase 3, Phase 2420
15Natriuretic Peptide, BrainPhase 1167
16
Epinephrineapproved76851-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
Auvi-q
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
Epinephrine chloride
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr
Epipen Jr.
Epipen Jr. Auto-Injector
Epipen jr
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
 
Esphygmogenina
Exadrin
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
Primatene Mist Refill
Prime Asthma Relief
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
17
substance Pinvestigational20433507-63-036511, 44359816
Synonyms:
 
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
18neurokinin A206
19
Hydrogen sulfide117783-06-4402
Synonyms:
Acide sulfhydrique
Dihydrogen disulfide
Dihydrogen monosulfide
Dihydrogen sulfide
Hepatate
Hepatic acid
Hepatic gas
Hydrogen monosulfide
Hydrogen sulfide
Hydrogen-sulfide
Hydrogene sulfure
 
Hydrosulfurate
Hydrosulfuric acid
Idrogeno solforato
Schwefelwasserstoff
Sewer gas
Siarkowodor
Sour gas
Stink dAMP
Sulfur hydride
Sulfur hydroxide
Sulfureted hydrogen
Sulfuretted hydrogen
Zwavelwaterstof
20Racepinephrine768
21Epinephryl borate768
22Plasminogen Inactivators9
23Plasminogen177
24Plasminogen Activator Inhibitor 127

Interventional clinical trials:

(show all 24)
idNameStatusNCT IDPhase
1The Role of the P2Y12 Receptor in Tissue Factor Induced CoagulationCompletedNCT01099566Phase 4
2A Comparison Study of Bypassing Agent Therapy With and Without Tranexamic Acid in Haemophilia A Patients With InhibitorCompletedNCT01800435Phase 4
3Clinical Pharmacokinetics Study of ART-123 in Disseminated Intravascular Coagulation (DIC) Subjects With Renal ImpairmentRecruitingNCT01704001Phase 4
4Different Schemes of Magnesium Sulfate for PreeclampsiaRecruitingNCT02396030Phase 4
5An Open-label Study of KW-3357CompletedNCT01384903Phase 3
6A Clinical Study of KW-3357 in Patients With DICCompletedNCT01384396Phase 3
7Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in SepsisCompletedNCT02135770Phase 3
8Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular CoagulationNot yet recruitingNCT02654561Phase 3
9The Effect of Ulinastatin on Bronchoalveolar Lavage Fluid of Inflammatory Factors in Patients With Ventilator-associated PneumoniaNot yet recruitingNCT01865266Phase 2, Phase 3
10A Phase 3 Clinical Study of KW-3357 in Patients With DICTerminatedNCT01384409Phase 3
11Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular CoagulationCompletedNCT00487656Phase 2
12Recombinant Human Antithrombin (ATryn®) in the Treatment of Patients With DIC Associated With Severe SepsisTerminatedNCT00506519Phase 2
13Study to Look at the Effects of ART-123 on Patients With Sepsis and Disseminated Intravascular Coagulation (DIC)WithdrawnNCT01090115Phase 2
14A Comparison of B Type Natriuretic Peptide Levels and Hemodynamics Using the Nexfin Device in Healthy Pregnant and Preeclamptic Women - A Pilot StudyRecruitingNCT02527018Phase 1
15Coagulation Factor Changes Associated With Postpartum HysterectomiesCompletedNCT00456547
16Correlation Between Cytokines and the Severity of Meningococcal DiseaseCompletedNCT01133834
17The Procalcitonin and Survival StudyCompletedNCT00271752
18Study of New Biological Markers for Prediction of Severe Acute PancreatitisCompletedNCT00786591
19TC-325 (HEMOSPRAY™) VS. CURRENT STANDARD OF CARE IN MANAGING MALIGNANT GASTROINTESTINAL BLEEDING: A PILOT STUDY TO INFORM A RANDOMIZED CONTROLLED TRIAL.RecruitingNCT02135627
20Hypercoagulation Screening in CancerRecruitingNCT02622815
21Interest of the Balance of Pro-coagulating and Profibrinolytis Activities of the Microparticles (MP) in the Prognosis of Septic ShockRecruitingNCT02062970
22Oxidative Stress and Endothelial Function in Pregnancy ComplicationsRecruitingNCT02603913
234G/5G Polymorphism of Plasminogen Activator Inhibitor-1 Gene and Disseminated Intravascular Coagulation in Severe Sepsis and Septic ShockNot yet recruitingNCT01211899
24Thrombin Generation and Thromboelastography in Non-overt DICTerminatedNCT00299949

Search NIH Clinical Center for Disseminated Intravascular Coagulation

Inferred drug relations via UMLS65/NDF-RT43:

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Cochrane evidence based reviews: Disseminated Intravascular Coagulation

Genetic Tests for Disseminated Intravascular Coagulation

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Anatomical Context for Disseminated Intravascular Coagulation

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MalaCards organs/tissues related to Disseminated Intravascular Coagulation:

33
Liver, Bone, Prostate, Neutrophil, Endothelial, Testes, Kidney

Animal Models for Disseminated Intravascular Coagulation or affiliated genes

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MGI Mouse Phenotypes related to Disseminated Intravascular Coagulation:

38 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.5ADAMTS13, ELANE, F2, F3, FN1, PROCR
2MP:00053888.3F2, MB, PLAT, PLG, SERPINE1, THBD
3MP:00053708.2F5, F9, FGA, PLG, SERPINC1, SERPINE1
4MP:00053897.6F2, FGA, FN1, PLAT, PLG, SERPINC1
5MP:00107717.5F2, F3, F5, FGA, FN1, PLG
6MP:00053807.3F2, F3, F5, F9, FGA, FN1
7MP:00036317.2F2, F3, F5, FGA, FN1, PLAT
8MP:00053786.8F2, F3, F5, FN1, MB, PLAT
9MP:00053856.4F2, F3, F5, F9, FGA, FN1
10MP:00053875.5ADAMTS13, ELANE, F2, F3, F9, FGA
11MP:00107685.1ADAMTS13, ELANE, F2, F3, F5, F9
12MP:00053974.9ADAMTS13, ELANE, F2, F3, F9, FGA
13MP:00053764.3ADAMTS13, ELANE, F2, F3, F5, F9

Publications for Disseminated Intravascular Coagulation

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Articles related to Disseminated Intravascular Coagulation:

(show top 50)    (show all 813)
idTitleAuthorsYear
1
Successful treatment with recombinant thrombomodulin for disseminated intravascular coagulation complicated with hemophagocytic syndrome. (25876785)
2015
2
Asphyxia by Drowning Induces Massive Bleeding Due To Hyperfibrinolytic Disseminated Intravascular Coagulation. (26327200)
2015
3
Management of cancer-associated disseminated intravascular coagulation: guidance from the SSC of the ISTH: reply. (25854143)
2015
4
Intrapartum anti-disseminated intravascular coagulation therapy leading to successful vaginal delivery following intrauterine fetal death caused by placental abruption: a case report. (25532532)
2014
5
Complement, thrombotic microangiopathy and disseminated intravascular coagulation. (25705421)
2014
6
Disseminated intravascular coagulation does not play a major role in the pathogenesis of classical swine fever. (23107658)
2013
7
Current consideration and management of disseminated intravascular coagulation. (24319193)
2013
8
Recombinant human soluble thrombomodulin in sepsis-induced disseminated intravascular coagulation: a multicenter propensity score analysis. (23361628)
2013
9
The withdrawal of Activated Protein C from the use in patients with severe sepsis and DIC [Amendment to the BCSH guideline on disseminated intravascular coagulation]. (22225506)
2012
10
The utility of a diagnostic scoring system for disseminated intravascular coagulation. (22713612)
2012
11
Oxaliplatin induced disseminated intravascular coagulation: A case report and review of literature. (22844549)
2012
12
Kocher-DebrAc-SAcmAclaigne syndrome diagnosed by autopsy associated with disseminated intravascular coagulation. (21316996)
2012
13
Effects of antithrombin and gabexate mesilate on disseminated intravascular coagulation: a preliminary study. (22204993)
2012
14
Successful treatment of sepsis-induced disseminated intravascular coagulation in a patient with idiopathic thrombocytopenic purpura using recombinant human soluble thrombomodulin. (21240494)
2011
15
Disseminated Intravascular Coagulation, Hemoperitoneum, and Reversible Ischemic Neurological Deficit Complicating Anaphylaxis to Prophylactic Antibiotics during Cesarean Delivery: A Case Report and Review of Literature. (23705078)
2011
16
Model-based analysis of covariate effects on population pharmacokinetics of thrombomodulin alfa in patients with disseminated intravascular coagulation and normal subjects. (21098690)
2011
17
A difficult diagnosis case of prolonged thrombocytopenia with sepsis and disseminated intravascular coagulation. (20530051)
2011
18
Disseminated intravascular coagulation with intracranial haematoma in neonatal congenital syphilis. (20889622)
2011
19
Multiple organ infarctions following disseminated intravascular coagulation precipitated by sepsis in a healthy infant: a case report. (21186015)
2010
20
Disseminated intravascular coagulation complicating Epstein-Barr virus infection in a cardiac transplant recipient: a case report. (20620559)
2010
21
Disseminated intravascular coagulation or extended intravascular coagulation in massive pulmonary embolism. (20412432)
2010
22
Successful treatment of disseminated intravascular coagulation in a child with acute myelogenous leukaemia using recombinant thrombomodulin. (20346017)
2010
23
Disseminated intravascular coagulation in infectious disease. (20614389)
2010
24
Influence of antithrombin and argatroban on disseminated intravascular coagulation parameters in a patient with septic shock. (19062078)
2009
25
Pathophysiology and diagnostic criteria for disseminated intravascular coagulation associated with sepsis. (18158452)
2008
26
Anti-heparin/PF4 complexes by ELISA in patients with disseminated intravascular coagulation. (20224256)
2007
27
Case report: Disseminated intravascular coagulation as the presenting sign of metastatic prostate cancer. (17458572)
2007
28
Diagnosis and treatment of disseminated intravascular coagulation: a case report. (17604485)
2007
29
Thrombin generation by exposure of blood to endotoxin: a simple model to study disseminated intravascular coagulation. (16708116)
2006
30
Patient with disseminated intravascular coagulation as the first manifestation of adenocarcinoma of the prostate. Risks of prostatic biopsy. (16331297)
2006
31
A systematic review of antithrombin concentrate use in patients with disseminated intravascular coagulation of severe sepsis. (16988545)
2006
32
Disseminated Intravascular Coagulation syndrome - ENT surgeon's perspective. (23120357)
2006
33
Disseminated intravascular coagulation in cats. (17186846)
2006
34
Disseminated intravascular coagulation after laparoscopic multiple myomectomy with use of icodextrin: a case report. (16962537)
2006
35
Settling the score for disseminated intravascular coagulation. (16215405)
2005
36
Plasma concentrations and importance of High Mobility Group Box protein in the prognosis of organ failure in patients with disseminated intravascular coagulation. (16363239)
2005
37
Good or poor responses of hemostatic molecular markers in patients with hematopoietic disorders after treatment of disseminated intravascular coagulation. (12643327)
2003
38
Disseminated intravascular coagulation]. (12806952)
2003
39
Microscopic polyangiitis associated with marked systemic bleeding tendency caused by disseminated intravascular coagulation. (14518675)
2003
40
Etiopathophysiology of disseminated intravascular coagulation. (14651143)
2003
41
Current drug treatment strategies for disseminated intravascular coagulation. (9617592)
1998
42
Antithrombin III in the treatment of disseminated intravascular coagulation]. (9045459)
1997
43
The antithrombotic effects of recombinant human soluble thrombomodulin (rhsTM) on tissue factor-induced disseminated intravascular coagulation in crab-eating monkeys (Macaca fascicularis). (9282791)
1997
44
Disseminated intravascular coagulation associated with granulocyte colony-stimulating factor therapy in a child with human immunodeficiency virus infection. (7538574)
1995
45
Megakaryoblastic transformation associated with disseminated intravascular coagulation in the course of polycythemia vera: a case report]. (1602615)
1992
46
Disseminated intravascular coagulation in liver cirrhosis. (1447499)
1992
47
The specific activity of plasminogen activator inhibitor-1 in disseminated intravascular coagulation with acute promyelocytic leukemia. (1708294)
1991
48
Disseminated intravascular coagulation masking neonatal hemophilia]. (2039186)
1991
49
Disseminated intravascular coagulation in dissecting aortic aneurysm. A case report. (7290724)
1981
50
Acute disseminated intravascular coagulation as the presenting and predominant clinical manifestation in a patient with a mucinous adenocarcinoma. (4376755)
1974

Variations for Disseminated Intravascular Coagulation

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Expression for genes affiliated with Disseminated Intravascular Coagulation

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Search GEO for disease gene expression data for Disseminated Intravascular Coagulation.

Pathways for genes affiliated with Disseminated Intravascular Coagulation

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Pathways related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

(show all 18)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9F2, F9
29.4F2, PLG
39.4FN1, PLAT, SERPINE1
49.3PLAT, PLG
5
Show member pathways
9.3F2, FGA, FN1
6
Show member pathways
8.9F2, FN1, PROCR, THBD
78.9F2, FN1, PLG
8
Show member pathways
8.8F2, PLAT, PLG, SERPINE1
98.5FN1, PLAT, PLG, SERPINE1
108.5ELANE, FN1, PLAT, PLG
11
Show member pathways
8.4F2, F3, F5, F9, FGA, SERPINC1
128.4PLAT, PLG, SERPINE1, SERPINF2
138.4FGA, FN1, PLAT, PLG
14
Show member pathways
8.0ELANE, FGA, FN1, PLG, SERPINE1
15
Show member pathways
7.3F3, F5, FGA, FN1, PLG, SERPINE1
16
Show member pathways
6.4F2, F3, F5, F9, FGA, PLAT
17
Show member pathways
5.9F2, F3, F5, F9, FGA, PLAT
18
Show member pathways
5.3F2, F3, F5, F9, FGA, FN1

GO Terms for genes affiliated with Disseminated Intravascular Coagulation

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Cellular components related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1platelet alpha granuleGO:003109110.4F5, FGA
2fibrinogen complexGO:00055779.6FGA, FN1, SERPINF2
3endoplasmic reticulum lumenGO:00057889.6ADAMTS13, F2, F5, F9
4extracellular matrixGO:00310129.2F2, F3, FN1, PLAT, SERPINE1
5blood microparticleGO:00725628.2F2, FGA, FN1, PLG, SERPINC1, SERPINF2
6platelet alpha granule lumenGO:00310938.1F5, FGA, FN1, PLG, SERPINE1, SERPINF2
7plasma membraneGO:00058866.9F2, F3, F5, F9, FGA, PLG
8cell surfaceGO:00099866.6ADAMTS13, ELANE, F3, FGA, PLAT, PLG
9extracellular regionGO:00055765.4ELANE, F2, F5, F9, FGA, FN1
10extracellular exosomeGO:00700625.1ELANE, F2, F3, F9, FGA, FN1
11extracellular spaceGO:00056154.9ADAMTS13, ELANE, F2, F3, F5, F9

Biological processes related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

(show all 25)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of platelet activationGO:001054410.6F2, THBD
2positive regulation of blood coagulationGO:003019410.5F2, SERPINE1
3negative regulation of blood coagulationGO:003019510.5SERPINE1, THBD
4blood coagulation, extrinsic pathwayGO:000759810.5F3, F9
5blood coagulation, intrinsic pathwayGO:000759710.5F2, F9
6peptidyl-glutamic acid carboxylationGO:001718710.5F2, F9
7negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:190204210.4FGA, SERPINE1
8positive regulation of collagen biosynthetic processGO:003296710.3F2, SERPINF2
9negative regulation of plasminogen activationGO:001075710.2SERPINE1, SERPINF2
10plasminogen activationGO:003163910.1FGA, PLAT
11response to woundingGO:000961110.0F2, F3, FN1
12negative regulation of endopeptidase activityGO:00109519.7SERPINC1, SERPINE1, SERPINF2
13post-translational protein modificationGO:00436879.7ADAMTS13, F2, F5, F9
14cell-matrix adhesionGO:00071609.5ADAMTS13, FGA, FN1
15acute-phase responseGO:00069539.2F2, FGA, FN1, SERPINF2
16extracellular matrix disassemblyGO:00226179.1ELANE, FN1, PLG
17leukocyte migrationGO:00509009.0ELANE, F2, FN1, PROCR, THBD
18negative regulation of fibrinolysisGO:00519188.9F2, PLG, SERPINE1, SERPINF2, THBD
19cellular protein metabolic processGO:00442678.4ADAMTS13, F2, F5, F9, FGA, PLG
20fibrinolysisGO:00427308.4F2, FGA, PLAT, PLG, SERPINE1, SERPINF2
21proteolysisGO:00065088.3ADAMTS13, ELANE, F2, F9, PLAT, PLG
22platelet degranulationGO:00025768.0F5, FGA, FN1, PLG, SERPINE1, SERPINF2
23extracellular matrix organizationGO:00301988.0ELANE, FGA, FN1, PLG, SERPINE1
24platelet activationGO:00301686.7ADAMTS13, F2, F5, FGA, FN1, PLG
25blood coagulationGO:00075965.2F2, F3, F5, F9, FGA, FN1

Molecular functions related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endopeptidase activityGO:00041759.7ADAMTS13, ELANE, F9
2serine-type endopeptidase inhibitor activityGO:00048679.4SERPINC1, SERPINE1, SERPINF2
3peptidase activityGO:00082339.1ADAMTS13, ELANE, F2, F9
4protease bindingGO:00020208.7ELANE, F3, FN1, SERPINC1, SERPINE1, SERPINF2
5serine-type endopeptidase activityGO:00042528.7ELANE, F2, F9, PLAT, PLG
6receptor bindingGO:00051028.1F2, FGA, PLAT, PLG, SERPINE1

Sources for Disseminated Intravascular Coagulation

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet