MCID: DSS009
MIFTS: 52

Disseminated Intravascular Coagulation malady

Categories: Immune diseases, Blood diseases

Aliases & Classifications for Disseminated Intravascular Coagulation

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Aliases & Descriptions for Disseminated Intravascular Coagulation:

Name: Disseminated Intravascular Coagulation 11 13 25 48 37 66
Diffuse or Disseminated Intravascular Coagulation 11
 
Defibrination Syndrome 11
Dic 11

Classifications:



External Ids:

Disease Ontology11 DOID:11247
ICD1028 D65
ICD9CM30 286.6
SNOMED-CT60 267563002, 67406007
MeSH37 D004211
NCIt43 C2992

Summaries for Disseminated Intravascular Coagulation

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Wikipedia:69 Disseminated intravascular coagulation (DIC), also known as disseminated intravascular coagulopathy or... more...

MalaCards based summary: Disseminated Intravascular Coagulation, also known as diffuse or disseminated intravascular coagulation, is related to factor x deficiency and systemic lupus erythematosus, and has symptoms including mahler sign An important gene associated with Disseminated Intravascular Coagulation is SERPINC1 (Serpin Family C Member 1), and among its related pathways are Warfarin Pathway, Pharmacodynamics and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). The drugs antithrombin iii, human and antithrombin iii,recombinant have been mentioned in the context of this disorder. Affiliated tissues include liver, prostate and neutrophil, and related mouse phenotypes are integument and neoplasm.

Related Diseases for Disseminated Intravascular Coagulation

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Diseases related to Disseminated Intravascular Coagulation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 348)
idRelated DiseaseScoreTop Affiliating Genes
1factor x deficiency30.5F2, F3, F7
2systemic lupus erythematosus29.9ADAMTS13, F2, F3, IL6, THBD
3non-secretory myeloma29.9IL6, VWF
4malaria29.6ADAMTS13, F3, IL6, THBD, VWF
5myocardial infarction26.0ADAMTS13, F2, F3, F7, IL6, PLAT
6dic in newborn11.7
7purpura fulminans11.3
8cavernous sinus thrombosis10.8F3, SERPINC1
9subcortical arteriosclerotic encephalopathy10.8F2, SERPINC1
10hepatic fibrosis renal cysts mental retardation10.8F3, SERPINC1
11familial glomangioma10.8F2, F3
12cerebral angioma10.7F2, F3
13classic congenital lipoid adrenal hyperplasia due to star deficency10.7F2, F3
14spleen cancer10.7F2, SERPINC1
15protein c deficiency10.7
16thrombophilia due to thrombin defect10.7F2, SERPINC1
17epididymo-orchitis10.7F2, F3
18unicentric castleman disease10.7F2, SERPINE1
19chorea gravidarum10.7F2, F3
20congenital nystagmus10.6F2, F3
21acute zonal occult outer retinopathy10.6F2, IL6
22peroneal neuropathy10.6F2, F3
23myiasis10.6F2, F3, SERPINC1
24marek disease10.6F2, F3, SERPINC1
25ovarian gonadoblastoma10.6F2, F3, SERPINC1
26dmd-related dilated cardiomyopathy10.6F2, F3, SERPINC1
27typhoid fever10.6F2, F7
28lingual-facial-buccal dyskinesia10.6F2, F3, SERPINC1
29dermatitis10.6F2, F3, SERPINC1
30leukemia10.6
31may-hegglin anomaly10.6F2, SERPINC1
32stickler sydrome, type i, nonsyndromic ocular10.6SERPINC1, SERPINE1, THBD
33collagenous colitis10.5F2, SERPINC1, SERPINE1
34hypertensive heart disease10.5F2, SERPINC1, SERPINE1
35mullerian aplasia10.5THBD, VWF
36facial hemiatrophy10.5F2, SERPINC1
37frontal sinus cancer10.5F2, SERPINC1, THBD
38posterolateral myocardial infarction10.5F2, SERPINC1, SERPINE1
39chromophobe adenoma10.5F3, SERPINE1, THBD
40preeclampsia/eclampsia 110.5SERPINC1, SERPINE1, THBD
41ovarian insufficiency, familial10.5F2, SERPINC1, SERPINE1
42splenic infarction10.5F2, F3
43histoplasmosis10.5F2, IL6, SERPINC1
44thrombophilia10.5F2, IL6, SERPINC1
45choroid necrotic melanoma10.5F3, IL6, SERPINC1
46bullous pemphigoid10.5ELANE, IL6
47left-right axis malformations10.5F2, SERPINC1, SERPIND1
48catatrichy10.5ADAMTS13, F3, SERPINE1
49aneurysm10.5
50mixed mineral dust pneumoconiosis10.5F2, IL6, SERPINC1

Comorbidity relations with Disseminated Intravascular Coagulation via Phenotypic Disease Network (PDN):


Deficiency AnemiaAcquired Thrombocytopenia
Active Peptic Ulcer DiseaseAcute Cystitis
Acute Kidney FailureChronic Kidney Failure
Decubitus UlcerFamilial Atrial Fibrillation
Heart DiseaseHereditary Ataxia
Left Ventricular Outflow Tract ObstructionMitral Valve Disease
Respiratory FailureProstate Cancer
Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Disseminated Intravascular Coagulation:



Diseases related to disseminated intravascular coagulation

Symptoms for Disseminated Intravascular Coagulation

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UMLS symptoms related to Disseminated Intravascular Coagulation:


mahler sign

Drugs & Therapeutics for Disseminated Intravascular Coagulation

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Drugs for Disseminated Intravascular Coagulation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Prasugrel hydrochloridePhase 4137389574-19-0
2THROMBINPhase 4284
3
Tranexamic AcidPhase 42411197-18-85526
Synonyms:
08455_FLUKA
1197-17-7
1197-18-8
1ceb
3-14-00-00868 (Beilstein Handbook Reference)
4-(Aminomethyl)-Cyclohexanecarboxylic Acid
4-(Aminomethyl)cyclohexanecarboxylic acid
4-(aminomethyl)cyclohexane-1-carboxylic acid
857653_ALDRICH
A0236
AB00052260
AB1003647
AC-4687
AC1L1KJH
AC1Q50F3
AC1Q546D
AC1Q5U04
ALBB-006013
AMCA
AMCHA
AMH
AR-1F6595
Acide tranexamique
Acide tranexamique [INN-French]
Acido tranexamico
Acido tranexamico [INN-Spanish]
Acidum tranexamicum
Acidum tranexamicum [INN-Latin]
Amikapron
Amstat
Anvitoff
BAY 3517
BPBio1_000069
BRN 2207452
BSPBio_000061
BSPBio_002837
CAS-1197-18-8
CHEBI:48669
CHEMBL292500
CHEMBL877
CID5526
CL 65336
CL-65336
Carxamin
Cyclocapron
Cyklokapron
Cyklokapron (TN)
D01136
DB00302
DV 79
DV-79
DV79
DivK1c_000655
EINECS 214-818-2
Emorhalt
Exacyl
Frenolyse
HMS1568D03
HMS1921F08
HMS2092P03
HMS502A17
Hexapromin
Hexatron
I04-0993
IDI1_000655
KABI 2161
KBio1_000655
KBio2_001871
KBio2_004439
KBio2_007007
KBio3_002337
KBioGR_000511
 
KBioSS_001871
LS-56611
LS-56612
LT00159441
Mastop
MolPort-001-792-390
MolPort-002-512-008
NCGC00016569-01
NCGC00016569-02
NCGC00016569-03
NCGC00094944-01
NCGC00094944-02
NINDS_000655
NSC 291305
NSC291305
Oprea1_786414
Prestwick0_000171
Prestwick1_000171
Prestwick2_000171
Prestwick3_000171
Prestwick_476
RP 18,429
Rikavarin
Rikavarin (TN)
Rikavarin-S
SPBio_000689
SPBio_001982
SPECTRUM1502026
STK503668
STOCK1N-16183
Spectrum2_000655
Spectrum3_001189
Spectrum4_000046
Spectrum5_001258
Spectrum_001391
Spiramin
Tamcha
Tranex
Tranexamate
Tranexamic acid (JP15/USAN/INN)
Tranexamic acid [USAN:INN:BAN:JAN]
Tranexamic acid cis-form
Tranexamsaeure
Tranexan
Tranexmic acid
Tranhexamic acid
Trans AMCHA
Trans-1-(Aminomethyl)cyclohexane-4-carboxylic acid
Trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid
Trans-p-(Aminomethyl)cyclohexanecarboxylic
Transamin
Transamin (TN)
Transamlon
Trasamlon
UNII-6T84R30KC1
Ugurol
WLN: L6TJ AVQ D1Z -T
cis-4-(Aminomethyl)cyclohexanecarboxylic acid
cis-4-Aminomethylcyclohexane-1-carboxylic acid
cis-AMCHA
t-AMCHA
tranexamic acid
tranexmic acid
trans-1-Aminomethylcyclohexane-4-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-carboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid ester
trans-4-Aminomethylcyclohexane-1-carboxylic acid
trans-4-aminomethylcyclohexane-1-carboxylic acid
trans-Amcha
trans-Tranexamic acid
trans-p-(Aminomethyl)cyclohexanecarboxylic acid
4FACTOR VIIIPhase 4282
5
Magnesium SulfatePhase 41597487-88-924083
Synonyms:
(C10-C16) Alkylalcohol sulfuric acid, magnesium salt
00627_FLUKA
10028-26-9
10034-99-8 (heptahydrate)
13143_RIEDEL
13143_SIAL
139939-75-6
18939-43-0
203726_ALDRICH
208094_SIAL
34276_FLUKA
34276_RIEDEL
38146_FLUKA
38146_RIEDEL
63126_FLUKA
63136_FLUKA
63136_SIAL
63139_FLUKA
63139_SIAL
68081-97-0
7487-88-9
AC1L2N76
AC1LAX36
AC1Q1U66
AI3-02029
Bitter salt
C10-C16 Alkyl alcohol sulfuric acid magnesium salt
CCRIS 8411
CHEBI:32599
CID24083
CPD0-2390
Caswell No. 534
D008278
DB00653
EINECS 231-298-2
EINECS 233-073-4
EINECS 242-691-3
EINECS 268-365-0
EPA Pesticide Chemical Code 050503
Epsom salt
HSDB 664
Hair salt
Heptahydrate Magnesium Sulfate
Kieserite [as monohydrate]
LS-88605
M2643_SIGMA
M3409_SIGMA
 
M7506_SIAL
M8150_SIGMA
MAGNESIUM SULFATE
Magnesium Sulfate In Plastic Container
Magnesium Sulfate, Heptahydrate
Magnesium Sulphate Hydrate
Magnesium bisulfate
Magnesium hydrogensulphate
Magnesium sulfate
Magnesium sulfate (1:1)
Magnesium sulfate anhydrous
Magnesium sulfate dried
Magnesium sulfate heptahydrate
Magnesium sulfate hexahydrate
Magnesium sulfate in dextrose 5% in plastic container
Magnesium sulfate solution
Magnesium sulphate
Magnesium sulphate anhydrous
Magnesium sulphate dried
Magnesium sulphate heptahydrate
Magnesium(II) sulfate
Magnesium(ii) sulfate
Magnesiumsulfat
MgSO4
MolPort-003-925-000
NSC 146179
OT-S
OT-S (drying agent)
SDA 15-062-07
Sal Angalis
Sal De sedlitz
Sal amarum
Sal anglicum
Sal catharticum
Sal seidlitense
Salts of england
Sel d'angleterre
Sulfate, Magnesium
Sulfuric acid magnesium salt
Sulfuric acid magnesium salt (1:1)
Sulfuric acid magnesium salt (VAN)
Sulfuric acid, C10-16 alkyl ester, magnesium salt
Sulfuric acid, magnesium salt
Sulfuric acid, magnesium salt (1:1)
Sulfuric acid, mono-C10-16-alkyl esters, magnesium salts
Tomix OT
UNII-DE08037SAB
UNII-ML30MJ2U7I
magnesium(2+) ion sulfate
6calcium channel blockersPhase 41889
7
HeparinPhase 37799005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Unfractionated heparin
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
8calcium heparinPhase 3779
9
protease inhibitorsPhase 3, Phase 25157
Synonyms:
 
protease inhibitors
10serineNutraceuticalPhase 3, Phase 2883
11
substance P23933507-63-044359816
Synonyms:
 
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
12neurokinin A242
13
Hydrogen sulfide137783-06-4402
Synonyms:
Acide sulfhydrique
Dihydrogen disulfide
Dihydrogen monosulfide
Dihydrogen sulfide
Hepatate
Hepatic acid
Hepatic gas
Hydrogen monosulfide
Hydrogen sulfide
Hydrogen-sulfide
Hydrogene sulfure
 
Hydrosulfurate
Hydrosulfuric acid
Idrogeno solforato
Schwefelwasserstoff
Sewer gas
Siarkowodor
Sour gas
Stink dAMP
Sulfur hydride
Sulfur hydroxide
Sulfureted hydrogen
Sulfuretted hydrogen
Zwavelwaterstof
14
Epinephrine88651-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9

Interventional clinical trials:

(show all 25)
idNameStatusNCT IDPhase
1The Role of the P2Y12 Receptor in Tissue Factor Induced CoagulationCompletedNCT01099566Phase 4
2A Comparison Study of Bypassing Agent Therapy With and Without Tranexamic Acid in Haemophilia A Patients With InhibitorCompletedNCT01800435Phase 4
3Clinical Pharmacokinetics Study of ART-123 in Disseminated Intravascular Coagulation (DIC) Subjects With Renal ImpairmentRecruitingNCT01704001Phase 4
4Different Schemes of Magnesium Sulfate for PreeclampsiaActive, not recruitingNCT02396030Phase 4
5An Open-label Study of KW-3357CompletedNCT01384903Phase 3
6A Clinical Study of KW-3357 in Patients With DICCompletedNCT01384396Phase 3
7Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in SepsisCompletedNCT02135770Phase 3
8Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular CoagulationNot yet recruitingNCT02654561Phase 3
9The Effect of Ulinastatin on Bronchoalveolar Lavage Fluid of Inflammatory Factors in Patients With Ventilator-associated PneumoniaNot yet recruitingNCT01865266Phase 2, Phase 3
10A Phase 3 Clinical Study of KW-3357 in Patients With DICTerminatedNCT01384409Phase 3
11Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular CoagulationCompletedNCT00487656Phase 2
12Recombinant Human Antithrombin (ATryn®) in the Treatment of Patients With DIC Associated With Severe SepsisTerminatedNCT00506519Phase 2
13Study to Look at the Effects of ART-123 on Patients With Sepsis and Disseminated Intravascular Coagulation (DIC)WithdrawnNCT01090115Phase 2
14A Comparison of B Type Natriuretic Peptide Levels and Hemodynamics Using the Nexfin Device in Healthy Pregnant and Preeclamptic Women - A Pilot StudyRecruitingNCT02527018Phase 1
15Coagulation Factor Changes Associated With Postpartum HysterectomiesCompletedNCT00456547
16Correlation Between Cytokines and the Severity of Meningococcal DiseaseCompletedNCT01133834
17The Procalcitonin and Survival StudyCompletedNCT00271752
18Role of the Circulating Procoagulants Microparticles in the Hypercoagulability of MNP Ph1-CompletedNCT02862366
19Study of New Biological Markers for Prediction of Severe Acute PancreatitisCompletedNCT00786591
20TC-325 (HEMOSPRAY™) VS. CURRENT STANDARD OF CARE IN MANAGING MALIGNANT GASTROINTESTINAL BLEEDING: A PILOT STUDY TO INFORM A RANDOMIZED CONTROLLED TRIAL.RecruitingNCT02135627
21Hypercoagulation Screening in CancerRecruitingNCT02622815
22Interest of the Balance of Pro-coagulating and Profibrinolytis Activities of the Microparticles (MP) in the Prognosis of Septic ShockRecruitingNCT02062970
23Oxidative Stress and Endothelial Function in Pregnancy ComplicationsRecruitingNCT02603913
244G/5G Polymorphism of Plasminogen Activator Inhibitor-1 Gene and Disseminated Intravascular Coagulation in Severe Sepsis and Septic ShockNot yet recruitingNCT01211899
25Thrombin Generation and Thromboelastography in Non-overt DICTerminatedNCT00299949

Search NIH Clinical Center for Disseminated Intravascular Coagulation

Inferred drug relations via UMLS66/NDF-RT44:

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Cochrane evidence based reviews: disseminated intravascular coagulation

Genetic Tests for Disseminated Intravascular Coagulation

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Genetic tests related to Disseminated Intravascular Coagulation:

id Genetic test Affiliating Genes
1 Disseminated Intravascular Coagulation25

Anatomical Context for Disseminated Intravascular Coagulation

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MalaCards organs/tissues related to Disseminated Intravascular Coagulation:

34
Liver, Prostate, Neutrophil, Bone, Endothelial, Testes, Kidney

Animal Models for Disseminated Intravascular Coagulation or affiliated genes

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MGI Mouse Phenotypes related to Disseminated Intravascular Coagulation:

39 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.6F2, F3, IL6, PLG, SERPINE1, TFPI
2MP:00020068.4CPB2, ELANE, F3, IL6, PLG, SERPINE1
3MP:00053888.2CPB2, F2, IL6, PLAT, PLG, SERPINE1
4MP:00053818.0F2, IL6, PLAT, PLG, THBD, VWF
5MP:00053677.7CPB2, IL6, PLG, SERPINC1, SERPIND1, SERPINE1
6MP:00036317.0F2, F3, IL6, PLAT, PLG, SERPINC1
7MP:00053786.7CPB2, F2, F3, F7, IL6, PLAT
8MP:00053975.9ADAMTS13, ELANE, F2, F3, IL6, PLAT
9MP:00053855.8F2, F3, F7, IL6, PLAT, PLG
10MP:00053875.7ADAMTS13, CPB2, ELANE, F2, F3, IL6
11MP:00107684.6ADAMTS13, CPB2, ELANE, F2, F3, F7
12MP:00053764.5ADAMTS13, CPB2, ELANE, F2, F3, F7

Publications for Disseminated Intravascular Coagulation

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Articles related to Disseminated Intravascular Coagulation:

(show top 50)    (show all 859)
idTitleAuthorsYear
1
Evidence of NETosis in Septic Shock-induced Disseminated Intravascular Coagulation. (27488091)
2016
2
Assessment of Haemostasis in Disseminated Intravascular Coagulation by Use of Point-of-Care Assays and Routine Coagulation Tests, in Critically Ill Patients; A Prospective Observational Study. (26959974)
2016
3
Disseminated Intravascular Coagulation in Secondary Glioblastoma due to Excessive Intraoperative Bleeding: Case Report and Review of the Literature. (26921703)
2016
4
Successful treatment with recombinant thrombomodulin for disseminated intravascular coagulation complicated with hemophagocytic syndrome. (25876785)
2015
5
Asphyxia by Drowning Induces Massive Bleeding Due To Hyperfibrinolytic Disseminated Intravascular Coagulation. (26327200)
2015
6
Management of cancer-associated disseminated intravascular coagulation: guidance from the SSC of the ISTH: reply. (25854143)
2015
7
Potential diagnostic markers for disseminated intravascular coagulation of sepsis. (26574054)
2015
8
Intrapartum anti-disseminated intravascular coagulation therapy leading to successful vaginal delivery following intrauterine fetal death caused by placental abruption: a case report. (25532532)
2014
9
Complement, thrombotic microangiopathy and disseminated intravascular coagulation. (25705421)
2014
10
Addition of recommendations for the use of recombinant human thrombomodulin to the "Expert consensus for the treatment of disseminated intravascular coagulation in Japan". (25135793)
2014
11
Successful treatment of chronic disseminated intravascular coagulation using recombinant human soluble thrombomodulin in a dialysis patient with dissecting aortic aneurysm. (25501411)
2014
12
Disseminated intravascular coagulation does not play a major role in the pathogenesis of classical swine fever. (23107658)
2013
13
Current consideration and management of disseminated intravascular coagulation. (24319193)
2013
14
The effect of recombinant human soluble thrombomodulin on disseminated intravascular coagulation in an abdominal aortic aneurysm. (24378974)
2013
15
Two cases of disseminated intravascular coagulation due to "bath salts" resulting in fatalities, with laboratory confirmation. (22867829)
2013
16
The utility of a diagnostic scoring system for disseminated intravascular coagulation. (22713612)
2012
17
Oxaliplatin induced disseminated intravascular coagulation: A case report and review of literature. (22844549)
2012
18
Kocher-DebrAc-SAcmAclaigne syndrome diagnosed by autopsy associated with disseminated intravascular coagulation. (21316996)
2012
19
Successful treatment of sepsis-induced disseminated intravascular coagulation in a patient with idiopathic thrombocytopenic purpura using recombinant human soluble thrombomodulin. (21240494)
2011
20
Disseminated intravascular coagulation as the laboratory hallmark of acute Q fever. (21251568)
2011
21
Multiple organ infarctions following disseminated intravascular coagulation precipitated by sepsis in a healthy infant: a case report. (21186015)
2010
22
Disseminated intravascular coagulation complicating Epstein-Barr virus infection in a cardiac transplant recipient: a case report. (20620559)
2010
23
Disseminated intravascular coagulation in infectious disease. (20614389)
2010
24
Disseminated intravascular coagulation associated with ventriculoperitoneal shunt surgery. (20192651)
2010
25
Fatal Klebsiella pneumoniae meningitis and concomitant disseminated intravascular coagulation in a patient with diabetes mellitus. (19561976)
2009
26
Marantic endocarditis and disseminated intravascular coagulation with systemic emboli in presentation of pancreatic cancer. (18323562)
2008
27
Anti-heparin/PF4 complexes by ELISA in patients with disseminated intravascular coagulation. (20224256)
2007
28
Diagnosis and treatment of disseminated intravascular coagulation: a case report. (17604485)
2007
29
The critical analysis on diagnosis of disseminated intravascular coagulation with screening tests--a scoring system and related literature review. (18693613)
2007
30
Clinical usefulness of plasma interleukin-6 and interleukin-10 in disseminated intravascular coagulation]. (18094556)
2007
31
Thrombin generation by exposure of blood to endotoxin: a simple model to study disseminated intravascular coagulation. (16708116)
2006
32
Patient with disseminated intravascular coagulation as the first manifestation of adenocarcinoma of the prostate. Risks of prostatic biopsy. (16331297)
2006
33
Disseminated intravascular coagulation in cats. (17186846)
2006
34
Global fibrinolytic capacity in pediatric patients with sepsis and disseminated intravascular coagulation. (16988553)
2006
35
Settling the score for disseminated intravascular coagulation. (16215405)
2005
36
Disseminated intravascular coagulation in an ambulatory young woman. (16131459)
2005
37
Alternative treatments for disseminated intravascular coagulation. (15543251)
2004
38
Good or poor responses of hemostatic molecular markers in patients with hematopoietic disorders after treatment of disseminated intravascular coagulation. (12643327)
2003
39
Osteonecrosis after meningococcemia and disseminated intravascular coagulation. (14628777)
2003
40
Massive disseminated intravascular coagulation and hyperfibrinolysis in alveolar rhabdomyosarcoma: case report and review of the literature. (10466447)
1999
41
Epilogue: disseminated intravascular coagulation and antithrombin III in intensive care medicine: pathophysiological insights and therapeutic hopes. (9515783)
1998
42
Antithrombin III in the treatment of disseminated intravascular coagulation]. (9045459)
1997
43
Disseminated intravascular coagulation associated with granulocyte colony-stimulating factor therapy in a child with human immunodeficiency virus infection. (7538574)
1995
44
Phaeochromocytoma crisis in Sipple's syndrome with intrauterine death and disseminated intravascular coagulation. (15636849)
1993
45
Megakaryoblastic transformation associated with disseminated intravascular coagulation in the course of polycythemia vera: a case report]. (1602615)
1992
46
Disseminated intravascular coagulation in dissecting aortic aneurysm. A case report. (7290724)
1981
47
Harlequin gangrene: a case report of unilateral gangrene of the leg and arm with myxedema, septicemia and disseminated intravascular coagulation. (642612)
1978
48
Multiple bone marrow necrosis and disseminated intravascular coagulation. (579307)
1977
49
Dilantin-induced disseminated intravascular coagulation with purpura fulminans. A case report. (1147459)
1975
50
Acute disseminated intravascular coagulation as the presenting and predominant clinical manifestation in a patient with a mucinous adenocarcinoma. (4376755)
1974

Variations for Disseminated Intravascular Coagulation

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Expression for genes affiliated with Disseminated Intravascular Coagulation

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Search GEO for disease gene expression data for Disseminated Intravascular Coagulation.

Pathways for genes affiliated with Disseminated Intravascular Coagulation

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Pathways related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

(show all 13)
idSuper pathwaysScoreTop Affiliating Genes
19.9F2, F7
29.9F2, PLG
39.5F2, PLG, TFPI
49.4PLAT, PLG, SERPINE1
59.4PLAT, PLG, SERPINE1
69.1IL6, PLAT, SERPINE1
79.1F3, IL6, SERPINE1, THBD
8
Show member pathways
8.8F2, F3, F7, SERPINC1, TFPI, THBD
98.6ELANE, IL6, PLAT, PLG
10
Show member pathways
8.2F2, F7, IL6, PLAT, PLG, SERPINE1
11
Show member pathways
6.4F2, F3, F7, PLAT, PLG, SERPINC1
12
Show member pathways
6.4F2, F3, F7, PLAT, PLG, SERPINC1
13
Show member pathways
6.0CPB2, F2, F3, F7, PLAT, PLG

GO Terms for genes affiliated with Disseminated Intravascular Coagulation

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Cellular components related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:00725629.9F2, PLG, SERPINC1
2platelet alpha granule lumenGO:00310939.7PLG, SERPINE1, VWF
3extracellular matrixGO:00310128.8F2, F3, PLAT, SERPINE1, VWF
4cell surfaceGO:00099868.1ADAMTS13, ELANE, F3, PLAT, PLG, TFPI
5extracellular exosomeGO:00700626.4CPB2, ELANE, F2, F3, PLAT, PLG
6extracellular regionGO:00055765.7ELANE, F2, F7, IL6, PLAT, PLG
7extracellular spaceGO:00056155.0ADAMTS13, CPB2, ELANE, F2, F3, F7

Biological processes related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of platelet-derived growth factor receptor signaling pathwayGO:001064110.7F3, F7
2negative regulation of platelet activationGO:001054410.6F2, THBD
3negative regulation of blood coagulationGO:003019510.6SERPINE1, THBD
4peptidyl-glutamic acid carboxylationGO:001718710.5F2, F7
5positive regulation of positive chemotaxisGO:005092710.5F3, F7
6signal peptide processingGO:000646510.5F2, F7
7negative regulation of plasminogen activationGO:001075710.4CPB2, SERPINE1
8blood coagulation, extrinsic pathwayGO:000759810.3F3, F7, TFPI
9acute inflammatory response to antigenic stimulusGO:000243810.2ELANE, SERPINC1
10protein processingGO:001648510.1ADAMTS13, F3, F7
11negative regulation of proteolysisGO:004586110.0F2, PLAT
12blood coagulation, intrinsic pathwayGO:000759710.0F2, VWF
13negative regulation of chemokine biosynthetic processGO:004507910.0ELANE, IL6
14positive regulation of leukocyte chemotaxisGO:000269010.0F7, IL6
15positive regulation of blood coagulationGO:003019410.0F2, F7, SERPINE1
16response to yeastGO:00018789.9ELANE, IL6
17response to estradiolGO:00323559.8F3, F7, TFPI
18positive regulation of protein kinase B signalingGO:00518979.8F3, F7, IL6
19negative regulation of endopeptidase activityGO:00109519.6SERPINC1, SERPIND1, SERPINE1, TFPI
20platelet degranulationGO:00025769.5PLG, SERPINE1, VWF
21negative regulation of fibrinolysisGO:00519189.5CPB2, F2, PLG, SERPINE1, THBD
22leukocyte migrationGO:00509009.4ELANE, F2, THBD
23fibrinolysisGO:00427309.3CPB2, F2, PLAT, PLG, SERPINE1
24cellular response to lipopolysaccharideGO:00712229.3ADAMTS13, IL6, SERPINE1, TFPI
25response to woundingGO:00096119.2F2, IL6, VWF
26response to lipopolysaccharideGO:00324968.8ELANE, F3, IL6, TFPI, THBD
27platelet activationGO:00301688.8ADAMTS13, F2, IL6, VWF
28proteolysisGO:00065087.8ADAMTS13, CPB2, ELANE, F2, PLAT, PLG
29blood coagulationGO:00075966.3CPB2, F2, F3, F7, PLAT, PLG

Molecular functions related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1serine-type endopeptidase inhibitor activityGO:00048679.5SERPINC1, SERPIND1, SERPINE1, TFPI
2peptidase activityGO:00082339.5ADAMTS13, ELANE, F2
3glycoprotein bindingGO:00019488.6F7, PLAT, VWF
4serine-type endopeptidase activityGO:00042528.4ELANE, F2, F3, F7, PLAT, PLG
5protease bindingGO:00020208.3ELANE, F3, SERPINC1, SERPINE1, VWF
6receptor bindingGO:00051028.2F2, F7, IL6, PLAT, PLG, SERPINE1

Sources for Disseminated Intravascular Coagulation

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet