MCID: DSS009
MIFTS: 51

Disseminated Intravascular Coagulation malady

Categories: Immune diseases, Blood diseases

Aliases & Classifications for Disseminated Intravascular Coagulation

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Aliases & Descriptions for Disseminated Intravascular Coagulation:

Name: Disseminated Intravascular Coagulation 11 27 50 39 13 68
Diffuse or Disseminated Intravascular Coagulation 11
 
Defibrination Syndrome 11
Dic 11

Classifications:



External Ids:

Disease Ontology11 DOID:11247
ICD1030 D65
ICD9CM32 286.6
SNOMED-CT62 267563002, 67406007
MeSH39 D004211
NCIt45 C2992

Summaries for Disseminated Intravascular Coagulation

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Wikipedia:71 Disseminated intravascular coagulation (DIC), also known as disseminated intravascular coagulopathy or... more...

MalaCards based summary: Disseminated Intravascular Coagulation, also known as diffuse or disseminated intravascular coagulation, is related to factor x deficiency and myocardial infarction, and has symptoms including mahler sign An important gene associated with Disseminated Intravascular Coagulation is SERPINC1 (Serpin Family C Member 1), and among its related pathways are AGE-RAGE signaling pathway in diabetic complications and Dissolution of Fibrin Clot. The drugs antithrombin iii,recombinant and antithrombin iii, human have been mentioned in the context of this disorder. Affiliated tissues include liver, prostate and neutrophil, and related mouse phenotypes are liver/biliary system and integument.

Related Diseases for Disseminated Intravascular Coagulation

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Diseases related to Disseminated Intravascular Coagulation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 346)
idRelated DiseaseScoreTop Affiliating Genes
1factor x deficiency29.3F2, F3, F7, F9
2myocardial infarction26.1ADAMTS13, F2, F3, F5, F7, FGA
3purpura fulminans11.8
4dic in newborn11.5
5kidney cortex necrosis11.1
6cavernous sinus thrombosis10.7F3, SERPINC1
7familial glomangioma10.6F2, F3
8cerebral angioma10.6F2, F3
9dislocation of ear ossicle10.6F2, F3
10spleen cancer10.6F2, SERPINC1
11von willibrand disease, type 310.6F2, F3
12epididymo-orchitis10.6F2, F3
13acute zonal occult outer retinopathy10.6F2, F5
14congenital stenosis of the inferior vena cava10.6F5, SERPINE1
15ameloblastic carcinoma10.6F5, SERPINE1
16chorea gravidarum10.6F2, F3
17bartholin's gland adenoma10.6F2, F5
18peroneal neuropathy10.6F2, F3
19mesangioproliferative glomerulopathy10.5PLAT, THBD
20shwachman-diamond type metaphyseal dysplasia10.5F3, SERPINE1
21myiasis10.5F2, F3, SERPINC1
22tympanosclerosis10.5F2, F5
23marek disease10.5F2, F3, SERPINC1
24ovarian gonadoblastoma10.5F2, F3, SERPINC1
25hepatic fibrosis renal cysts mental retardation10.5F3, F5, SERPINC1
26conjunctivochalasis10.5PLAT, SERPINC1
27histoplasmosis10.5F2, SERPINC1
28homocystinuria due to defect in methylation cbl g10.5F2, F5
29cerebral cavernous malformations 310.5PLAT, SERPINC1
30subcortical arteriosclerotic encephalopathy10.5F2, F5, SERPINC1
31splenic infarction10.5F2, F3
32congenital porphyria10.5PLAT, SERPINE1
33intracranial arteriosclerosis10.5F2, F3, SERPINC1
34thyroid hyalinizing trabecular adenoma10.5F2, F5, SERPINC1
35dermatitis10.5F2, F3, SERPINC1
36primary pigmented nodular adrenocortical disease10.5F2, F5
37thrombophilia due to thrombin defect10.5F2, F5, SERPINC1
38stickler sydrome, type i, nonsyndromic ocular10.5SERPINC1, SERPINE1, THBD
39may-hegglin anomaly10.5F2, F5, SERPINC1
40left-right axis malformations10.5F2, F5, SERPINC1
41focal epilepsy10.5F2, F3, SERPINC1
42classic congenital lipoid adrenal hyperplasia due to star deficency10.5F2, F3, F5
43congenital ectodermal dysplasia with hearing loss10.5F5, FGA
44thrombophilia10.5F2, F5, SERPINC1
45hypertensive heart disease10.5F2, SERPINC1, SERPINE1
46choroid necrotic melanoma10.4F3, F5, SERPINC1
47leukemia10.4
48joint disorders10.4F2, F5, SERPINC1
49lymphedema10.4F2, F3, SERPINC1
50macrocephaly mesodermal hamartoma spectrum10.4PLAT, THBD

Comorbidity relations with Disseminated Intravascular Coagulation via Phenotypic Disease Network (PDN):


Deficiency AnemiaAcquired Thrombocytopenia
Active Peptic Ulcer DiseaseAcute Cystitis
Acute Kidney FailureChronic Kidney Failure
Decubitus UlcerFamilial Atrial Fibrillation
Heart DiseaseHereditary Ataxia
Left Ventricular Outflow Tract ObstructionMitral Valve Disease
Respiratory FailureProstate Cancer
Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Disseminated Intravascular Coagulation:



Diseases related to disseminated intravascular coagulation

Symptoms & Phenotypes for Disseminated Intravascular Coagulation

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UMLS symptoms related to Disseminated Intravascular Coagulation:


mahler sign

MGI Mouse Phenotypes related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053709.1F5, F9, FGA, SERPINC1, SERPINE1, THBD
2MP:00107718.7F2, F3, F5, FGA, SERPINE1, TFPI
3MP:00053808.0F2, F3, F5, F9, FGA, MB
4MP:00053977.8ADAMTS13, ELANE, F2, F3, F9, FGA
5MP:00053877.6ADAMTS13, ELANE, F2, F3, F9, FGA
6MP:00053856.6F2, F3, F5, F7, F9, FGA
7MP:00053765.3ADAMTS13, ELANE, F2, F3, F5, F7
8MP:00107685.1ADAMTS13, ELANE, F2, F3, F5, F7

Drugs & Therapeutics for Disseminated Intravascular Coagulation

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Drugs for Disseminated Intravascular Coagulation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 57)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Tranexamic AcidapprovedPhase 42571197-18-85526
Synonyms:
08455_FLUKA
1197-17-7
1197-18-8
1ceb
3-14-00-00868 (Beilstein Handbook Reference)
4-(Aminomethyl)-Cyclohexanecarboxylic Acid
4-(Aminomethyl)cyclohexanecarboxylic acid
4-(aminomethyl)cyclohexane-1-carboxylic acid
857653_ALDRICH
A0236
AB00052260
AB1003647
AC-4687
AC1L1KJH
AC1Q50F3
AC1Q546D
AC1Q5U04
ALBB-006013
AMCA
AMCHA
AMH
AR-1F6595
Acide tranexamique
Acide tranexamique [INN-French]
Acido tranexamico
Acido tranexamico [INN-Spanish]
Acidum tranexamicum
Acidum tranexamicum [INN-Latin]
Amikapron
Amstat
Anvitoff
BAY 3517
BPBio1_000069
BRN 2207452
BSPBio_000061
BSPBio_002837
CAS-1197-18-8
CHEBI:48669
CHEMBL292500
CHEMBL877
CID5526
CL 65336
CL-65336
Carxamin
Cyclocapron
Cyklokapron
Cyklokapron (TN)
D01136
DB00302
DV 79
DV-79
DV79
DivK1c_000655
EINECS 214-818-2
Emorhalt
Exacyl
Frenolyse
HMS1568D03
HMS1921F08
HMS2092P03
HMS502A17
Hexapromin
Hexatron
I04-0993
IDI1_000655
KABI 2161
KBio1_000655
KBio2_001871
KBio2_004439
KBio2_007007
KBio3_002337
KBioGR_000511
 
KBioSS_001871
LS-56611
LS-56612
LT00159441
Mastop
MolPort-001-792-390
MolPort-002-512-008
NCGC00016569-01
NCGC00016569-02
NCGC00016569-03
NCGC00094944-01
NCGC00094944-02
NINDS_000655
NSC 291305
NSC291305
Oprea1_786414
Prestwick0_000171
Prestwick1_000171
Prestwick2_000171
Prestwick3_000171
Prestwick_476
RP 18,429
Rikavarin
Rikavarin (TN)
Rikavarin-S
SPBio_000689
SPBio_001982
SPECTRUM1502026
STK503668
STOCK1N-16183
Spectrum2_000655
Spectrum3_001189
Spectrum4_000046
Spectrum5_001258
Spectrum_001391
Spiramin
Tamcha
Tranex
Tranexamate
Tranexamic acid (JP15/USAN/INN)
Tranexamic acid [USAN:INN:BAN:JAN]
Tranexamic acid cis-form
Tranexamsaeure
Tranexan
Tranexmic acid
Tranhexamic acid
Trans AMCHA
Trans-1-(Aminomethyl)cyclohexane-4-carboxylic acid
Trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid
Trans-p-(Aminomethyl)cyclohexanecarboxylic
Transamin
Transamin (TN)
Transamlon
Trasamlon
UNII-6T84R30KC1
Ugurol
WLN: L6TJ AVQ D1Z -T
cis-4-(Aminomethyl)cyclohexanecarboxylic acid
cis-4-Aminomethylcyclohexane-1-carboxylic acid
cis-AMCHA
t-AMCHA
tranexamic acid
tranexmic acid
trans-1-Aminomethylcyclohexane-4-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-carboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid ester
trans-4-Aminomethylcyclohexane-1-carboxylic acid
trans-4-aminomethylcyclohexane-1-carboxylic acid
trans-Amcha
trans-Tranexamic acid
trans-p-(Aminomethyl)cyclohexanecarboxylic acid
2
Magnesium Sulfateapproved, vet_approvedPhase 41687487-88-924083
Synonyms:
(C10-C16) Alkylalcohol sulfuric acid, magnesium salt
00627_FLUKA
10028-26-9
10034-99-8 (heptahydrate)
13143_RIEDEL
13143_SIAL
139939-75-6
18939-43-0
203726_ALDRICH
208094_SIAL
34276_FLUKA
34276_RIEDEL
38146_FLUKA
38146_RIEDEL
63126_FLUKA
63136_FLUKA
63136_SIAL
63139_FLUKA
63139_SIAL
68081-97-0
7487-88-9
AC1L2N76
AC1LAX36
AC1Q1U66
AI3-02029
Bitter salt
C10-C16 Alkyl alcohol sulfuric acid magnesium salt
CCRIS 8411
CHEBI:32599
CID24083
CPD0-2390
Caswell No. 534
D008278
DB00653
EINECS 231-298-2
EINECS 233-073-4
EINECS 242-691-3
EINECS 268-365-0
EPA Pesticide Chemical Code 050503
Epsom salt
HSDB 664
Hair salt
Heptahydrate Magnesium Sulfate
Kieserite [as monohydrate]
LS-88605
M2643_SIGMA
M3409_SIGMA
 
M7506_SIAL
M8150_SIGMA
MAGNESIUM SULFATE
Magnesium Sulfate In Plastic Container
Magnesium Sulfate, Heptahydrate
Magnesium Sulphate Hydrate
Magnesium bisulfate
Magnesium hydrogensulphate
Magnesium sulfate
Magnesium sulfate (1:1)
Magnesium sulfate anhydrous
Magnesium sulfate dried
Magnesium sulfate heptahydrate
Magnesium sulfate hexahydrate
Magnesium sulfate in dextrose 5% in plastic container
Magnesium sulfate solution
Magnesium sulphate
Magnesium sulphate anhydrous
Magnesium sulphate dried
Magnesium sulphate heptahydrate
Magnesium(II) sulfate
Magnesium(ii) sulfate
Magnesiumsulfat
MgSO4
MolPort-003-925-000
NSC 146179
OT-S
OT-S (drying agent)
SDA 15-062-07
Sal Angalis
Sal De sedlitz
Sal amarum
Sal anglicum
Sal catharticum
Sal seidlitense
Salts of england
Sel d'angleterre
Sulfate, Magnesium
Sulfuric acid magnesium salt
Sulfuric acid magnesium salt (1:1)
Sulfuric acid magnesium salt (VAN)
Sulfuric acid, C10-16 alkyl ester, magnesium salt
Sulfuric acid, magnesium salt
Sulfuric acid, magnesium salt (1:1)
Sulfuric acid, mono-C10-16-alkyl esters, magnesium salts
Tomix OT
UNII-DE08037SAB
UNII-ML30MJ2U7I
magnesium(2+) ion sulfate
3ThrombinPhase 4288
4Peripheral Nervous System AgentsPhase 422776
5Calcium, DietaryPhase 4, Phase 35525
6CoagulantsPhase 41428
7Factor VIIIPhase 4304
8Liver ExtractsPhase 43868
9HemostaticsPhase 41359
10Antifibrinolytic AgentsPhase 4459
11Platelet Aggregation InhibitorsPhase 42419
12ThromboplastinPhase 460
13Prasugrel hydrochloridePhase 4142389574-19-0
14Central Nervous System DepressantsPhase 412806
15Tocolytic AgentsPhase 4708
16calcium channel blockersPhase 41940
17AnalgesicsPhase 411287
18Anti-Arrhythmia AgentsPhase 42969
19AnestheticsPhase 49001
20AnticonvulsantsPhase 42620
21
Heparinapproved, investigationalPhase 38129005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Unfractionated heparin
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
22Trypsin InhibitorsPhase 2, Phase 3122
23UrinastatinPhase 2, Phase 314
24
protease inhibitorsPhase 2, Phase 35320
Synonyms:
 
protease inhibitors
25HIV Protease InhibitorsPhase 2, Phase 35319
26Fibrinolytic AgentsPhase 32317
27Serine Proteinase InhibitorsPhase 2, Phase 3850
28Pharmaceutical SolutionsPhase 3, Phase 27793
29calcium heparinPhase 3812
30AntithrombinsPhase 3, Phase 2672
31Antithrombin IIIPhase 3, Phase 2665
32AnticoagulantsPhase 3, Phase 22516
33serineNutraceuticalPhase 2, Phase 3921
34Natriuretic Peptide, BrainPhase 1178
35Natriuretic AgentsPhase 11645
36
Epinephrineapproved, vet_approved93351-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
37
Substance Pinvestigational24533507-63-044359816
Synonyms:
 
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
38Plasminogen Activator Inhibitor 129
39Plasminogen Inactivators10
40Plasminogen236
41Neurotransmitter Agents17734
42Racepinephrine933
43Epinephryl borate933
44Mydriatics763
45Antibiotics, Antitubercular6972
46Anti-Bacterial Agents10884
47Vasoconstrictor Agents2027
48Respiratory System Agents4818
49Adrenergic alpha-Agonists1625
50Adrenergic Agents5140

Interventional clinical trials:

(show all 25)
idNameStatusNCT IDPhase
1Clinical Pharmacokinetics Study of ART-123 in Disseminated Intravascular Coagulation (DIC) Subjects With Renal ImpairmentUnknown statusNCT01704001Phase 4
2The Role of the P2Y12 Receptor in Tissue Factor Induced CoagulationCompletedNCT01099566Phase 4
3A Comparison Study of Bypassing Agent Therapy With and Without Tranexamic Acid in Haemophilia A Patients With InhibitorCompletedNCT01800435Phase 4
4Different Schemes of Magnesium Sulfate for PreeclampsiaTerminatedNCT02396030Phase 4
5The Effect of Ulinastatin on Bronchoalveolar Lavage Fluid of Inflammatory Factors in Patients With Ventilator-associated PneumoniaUnknown statusNCT01865266Phase 2, Phase 3
6An Open-label Study of KW-3357CompletedNCT01384903Phase 3
7A Clinical Study of KW-3357 in Patients With DICCompletedNCT01384396Phase 3
8Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in SepsisCompletedNCT02135770Phase 3
9Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular CoagulationNot yet recruitingNCT02654561Phase 3
10A Phase 3 Clinical Study of KW-3357 in Patients With DICTerminatedNCT01384409Phase 3
11Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular CoagulationCompletedNCT00487656Phase 2
12Recombinant Human Antithrombin (ATryn®) in the Treatment of Patients With DIC Associated With Severe SepsisTerminatedNCT00506519Phase 2
13Study to Look at the Effects of ART-123 on Patients With Sepsis and Disseminated Intravascular Coagulation (DIC)WithdrawnNCT01090115Phase 2
14A Comparison of B Type Natriuretic Peptide Levels and Hemodynamics Using the Nexfin Device in Healthy Pregnant and Preeclamptic Women - A Pilot StudyRecruitingNCT02527018Phase 1
154G/5G Polymorphism of Plasminogen Activator Inhibitor-1 Gene and Disseminated Intravascular Coagulation in Severe Sepsis and Septic ShockUnknown statusNCT01211899
16Coagulation Factor Changes Associated With Postpartum HysterectomiesCompletedNCT00456547
17Role of the Circulating Procoagulants Microparticles in the Hypercoagulability of MNP Ph1-CompletedNCT02862366
18Study of New Biological Markers for Prediction of Severe Acute PancreatitisCompletedNCT00786591
19TC-325 (HEMOSPRAY™) VS. CURRENT STANDARD OF CARE IN MANAGING MALIGNANT GASTROINTESTINAL BLEEDING: A PILOT STUDY TO INFORM A RANDOMIZED CONTROLLED TRIAL.CompletedNCT02135627
20Correlation Between Cytokines and the Severity of Meningococcal DiseaseCompletedNCT01133834
21The Procalcitonin and Survival StudyCompletedNCT00271752
22Hypercoagulation Screening in CancerRecruitingNCT02622815
23Interest of the Balance of Pro-coagulating and Profibrinolytis Activities of the Microparticles (MP) in the Prognosis of Septic ShockRecruitingNCT02062970
24Oxidative Stress and Endothelial Function in Pregnancy ComplicationsRecruitingNCT02603913
25Thrombin Generation and Thromboelastography in Non-overt DICTerminatedNCT00299949

Search NIH Clinical Center for Disseminated Intravascular Coagulation

Inferred drug relations via UMLS68/NDF-RT46:

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Cochrane evidence based reviews: disseminated intravascular coagulation

Genetic Tests for Disseminated Intravascular Coagulation

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Genetic tests related to Disseminated Intravascular Coagulation:

id Genetic test Affiliating Genes
1 Disseminated Intravascular Coagulation27

Anatomical Context for Disseminated Intravascular Coagulation

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MalaCards organs/tissues related to Disseminated Intravascular Coagulation:

36
Liver, Prostate, Neutrophil, Bone, Endothelial, Testes, Brain

Publications for Disseminated Intravascular Coagulation

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Articles related to Disseminated Intravascular Coagulation:

(show top 50)    (show all 876)
idTitleAuthorsYear
1
Platinum-based Doublet Chemotherapy for Advanced Gastric Cancer with Disseminated Intravascular Coagulation. (28011507)
2017
2
Population pharmacokinetics of thrombomodulin alfa in pediatric patients with hematological malignancy and disseminated intravascular coagulation. (27734584)
2017
3
Erratum: Current Pathological and Laboratory Considerations in the Diagnosis of Disseminated Intravascular Coagulation. (27834077)
2017
4
Disseminated Intravascular Coagulation on Admission Predicts Complications and Poor Prognosis of Acute Pancreatitis: Analysis of the Nationwide Epidemiological Survey in Japan. (28085757)
2017
5
Evidence of NETosis in Septic Shock-induced Disseminated Intravascular Coagulation. (27488091)
2016
6
Assessment of Haemostasis in Disseminated Intravascular Coagulation by Use of Point-of-Care Assays and Routine Coagulation Tests, in Critically Ill Patients; A Prospective Observational Study. (26959974)
2016
7
Disseminated Intravascular Coagulation in Secondary Glioblastoma due to Excessive Intraoperative Bleeding: Case Report and Review of the Literature. (26921703)
2016
8
Helicobacter pylori Eradication Therapy for Thrombocytopenia after Surgery for Abdominal Aortic Aneurysm with Disseminated Intravascular Coagulation. (28018509)
2016
9
The thromboelastometric discrepancy between septic and trauma induced disseminated intravascular coagulation diagnosed by the scoring system from the Japanese association for acute medicine. (27495106)
2016
10
Diffuse Cutaneous Bullous Mastocytosis and Disseminated Intravascular Coagulation Postvaccination: A Case Report. (27436822)
2016
11
Impact of Recombinant Human Soluble Thrombomodulin for Disseminated Intravascular Coagulation. (27127163)
2016
12
Danazol-induced peliosis hepatis accompanied by disseminated intravascular coagulation in a patient with myelodysplastic syndrome transformed from aplastic anemia. (27599419)
2016
13
Melatonin does not affect disseminated intravascular coagulation but diminishes decreases in platelet count during subacute endotoxaemia in rats. (26916294)
2016
14
Comparison of Procedure-Based and Diagnosis-Based Identifications of Severe Sepsis and Disseminated Intravascular Coagulation in Administrative Data. (27064132)
2016
15
Priapism as the Presenting Complaint in Fatal Group A Streptococcal Induced Disseminated Intravascular Coagulation. (27989251)
2016
16
Revision of the Japanese Association for Acute Medicine (JAAM) disseminated intravascular coagulation (DIC) diagnostic criteria using antithrombin activity. (27629997)
2016
17
Evaluation of Disseminated Intravascular Coagulation Scores in Critically Ill Pediatric Patients. (27028791)
2016
18
Sepsis and disseminated intravascular coagulation. (27011792)
2016
19
Disseminated Intravascular Coagulation: A Practical Approach. (27031011)
2016
20
Successful Renal Transplantation of Deceased Donor Kidneys With 100% Glomerular Fibrin Thrombi and Acute Renal Failure Due To Disseminated Intravascular Coagulation. (27490412)
2016
21
Successful treatments with polymyxin B hemoperfusion and recombinant human thrombomodulin for fulminant Clostridium difficile-associated colitis with septic shock and disseminated intravascular coagulation: a case report. (27468959)
2016
22
Neutrophil Fluorescence: A New Indicator of Cell Activation During Septic Shock-Induced Disseminated Intravascular Coagulation. (27441905)
2016
23
Disseminated Intravascular Coagulation. (28013226)
2016
24
Disseminated intravascular coagulation with positive D-dimer: a controversial clinical feature in severe congenital factor XIII deficiency in southeast Iran. (26836269)
2016
25
Disseminated intravascular coagulation in the HELLP syndrome: how much do we really know? (27181089)
2016
26
Comparison of Two Diagnostic Scores of Disseminated Intravascular Coagulation in Pregnant Women Admitted to the ICU. (27861597)
2016
27
Massive Bleeding as the First Clinical Manifestation of Metastatic Prostate Cancer due to Disseminated Intravascular Coagulation with Enhanced Fibrinolysis. (27803823)
2016
28
The impact of disseminated intravascular coagulation on the outcome of cancer patients with venous thromboembolism: Erratum. (27380477)
2016
29
The efficacy and safety of antithrombin and recombinant human thrombomodulin combination therapy in patients with severe sepsis and disseminated intravascular coagulation. (27546744)
2016
30
Management of cancer-associated disseminated intravascular coagulation. (27067981)
2016
31
OC-10 - Disseminated intravascular coagulation at diagnosis strongly predicts both arterial and venous thrombosis in acute myeloid leukemia patients. (27161682)
2016
32
Lamotrigine-Induced Disseminated Intravascular Coagulation With Anticonvulsant Hypersensitivity Syndrome: A Case Report. (27063814)
2016
33
Pathological findings in a case of bone marrow carcinosis due to gastric cancer complicated by disseminated intravascular coagulation and thrombotic microangiopathy. (27357318)
2016
34
Is antithrombin III for sepsis-associated disseminated intravascular coagulation really ineffective? (27143022)
2016
35
Fatal Hemorrhage from Kidney after Endovascular Repair for Chronic Type B Dissection Complicated with Disseminated Intravascular Coagulation. (28018508)
2016
36
Spontaneous intracranial hypotension complicated by malignancyinduced disseminated intravascular coagulation: A case report. (27854087)
2016
37
Recombinant human soluble thrombomodulin and mortality in sepsis-induced disseminated intravascular coagulation. A multicentre retrospective study. (26939575)
2016
38
Disseminated intravascular coagulation at diagnosis is a strong predictor for both arterial and venous thrombosis in newly diagnosed acute myeloid leukemia. (27354723)
2016
39
Performance Evaluation of Five Different Disseminated Intravascular Coagulation (DIC) Diagnostic Criteria for Predicting Mortality in Patients with Complicated Sepsis. (27709865)
2016
40
Antithrombin Supplementation and Mortality in Sepsis-Induced Disseminated Intravascular Coagulation: A Multicenter Retrospective Observational Study. (27548460)
2016
41
Chronic disseminated intravascular coagulation induced by left atrial thrombus in a patient with giant "normal" heart: A case report. (28002328)
2016
42
Disseminated intravascular coagulation following administration of sunitinib. (27330781)
2016
43
Acute kidney injury and disseminated intravascular coagulation due to mercuric chloride poisoning. (27194836)
2016
44
Shock, acute disseminated intravascular coagulation, and microvascular thrombosis: is 'shock liver' the unrecognized provocateur of ischemic limb necrosis: reply. (27608440)
2016
45
Intramural hematoma of the colon caused by double-balloon enteroscopy in a patient with chronic disseminated intravascular coagulation. (27008555)
2016
46
Inherited Thrombotic Thrombocytopenic Purpura (Upshaw Schulman Syndrome) as Differential Diagnosis to Neonatal Septicaemia with Disseminated Intravascular Coagulation - a Case Series. (27383044)
2016
47
Advanced gastric cancer linitis plastica presented with disseminated intravascular coagulation. (27803086)
2016
48
Can recombinant human thrombomodulin increase survival among patients with severe septic-induced disseminated intravascular coagulation: a single-centre, open-label, randomised controlled trial. (28039291)
2016
49
Disseminated intravascular coagulation in paediatrics. (27540263)
2016
50
Disseminated Intravascular Coagulation Syndromes in Obstetrics. (26901325)
2016

Variations for Disseminated Intravascular Coagulation

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Expression for genes affiliated with Disseminated Intravascular Coagulation

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Search GEO for disease gene expression data for Disseminated Intravascular Coagulation.

Pathways for genes affiliated with Disseminated Intravascular Coagulation

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Pathways related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7F3, SERPINE1, THBD
29.3PLAT, SERPINE1, SERPINF2
3
Show member pathways
9.0F2, F7, F9
49.0F2, F7, F9
5
Show member pathways
6.7F2, F3, F5, F7, F9, FGA
6
Show member pathways
5.5F2, F3, F5, F7, F9, FGA
7
Show member pathways
5.5F2, F3, F5, F7, F9, FGA

GO Terms for genes affiliated with Disseminated Intravascular Coagulation

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Cellular components related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1extracellular matrixGO:003101210.2F2, F3, PLAT, SERPINE1
2fibrinogen complexGO:000557710.1FGA, SERPINF2
3platelet alpha granuleGO:003109110.0F5, FGA
4Golgi lumenGO:00057969.8F2, F7, F9
5blood microparticleGO:00725629.7F2, FGA, SERPINC1, SERPINF2
6endoplasmic reticulum lumenGO:00057889.0ADAMTS13, F2, F5, F7, F9
7platelet alpha granule lumenGO:00310938.6F5, FGA, SERPINE1, SERPINF2
8cell surfaceGO:00099868.2ADAMTS13, ELANE, F3, FGA, PLAT, SERPINF2
9extracellular exosomeGO:00700627.7ELANE, F2, F3, F9, FGA, MB
10plasma membraneGO:00058867.0F2, F3, F5, F7, F9, FGA
11extracellular regionGO:00055766.5ELANE, F2, F5, F7, F9, FGA
12extracellular spaceGO:00056155.7ADAMTS13, ELANE, F2, F3, F5, F7

Biological processes related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of platelet activationGO:001054410.7F2, THBD
2negative regulation of blood coagulationGO:003019510.7SERPINE1, THBD
3acute inflammatory response to antigenic stimulusGO:000243810.7ELANE, SERPINC1
4negative regulation of proteolysisGO:004586110.6F2, PLAT
5blood coagulation, intrinsic pathwayGO:000759710.6F2, F9
6plasminogen activationGO:003163910.4FGA, PLAT
7leukocyte migrationGO:005090010.3ELANE, F2, THBD
8positive regulation of collagen biosynthetic processGO:003296710.3F2, SERPINF2
9negative regulation of plasminogen activationGO:001075710.3SERPINE1, SERPINF2
10platelet activationGO:003016810.2ADAMTS13, F2, F5
11positive regulation of platelet-derived growth factor receptor signaling pathwayGO:001064110.1F3, F7
12positive regulation of positive chemotaxisGO:005092710.1F3, F7
13cellular response to lipopolysaccharideGO:007122210.1ADAMTS13, SERPINE1, TFPI
14acute-phase responseGO:00069539.8F2, FGA, SERPINF2
15positive regulation of blood coagulationGO:00301949.8F2, F7, SERPINE1
16protein processingGO:00164859.8ADAMTS13, F3, F7
17negative regulation of fibrinolysisGO:00519189.8F2, SERPINE1, SERPINF2, THBD
18response to genisteinGO:00335959.7F7, FGA
19peptidyl-glutamic acid carboxylationGO:00171879.7F2, F7, F9
20negative regulation of endopeptidase activityGO:00109519.5SERPINC1, SERPINE1, SERPINF2, TFPI
21response to lipopolysaccharideGO:00324969.5ELANE, F3, TFPI, THBD
22proteolysisGO:00065089.5ADAMTS13, ELANE, F2, F9, PLAT
23platelet degranulationGO:00025769.3F5, FGA, SERPINE1, SERPINF2
24ER to Golgi vesicle-mediated transportGO:00068889.3F2, F5, F7, F9
25fibrinolysisGO:00427309.2F2, FGA, PLAT, SERPINE1, SERPINF2
26blood coagulation, extrinsic pathwayGO:00075989.2F3, F7, F9, TFPI
27signal peptide processingGO:00064659.0F2, F7, F9
28response to estradiolGO:00323559.0F3, F7, FGA, TFPI
29blood coagulationGO:00075967.2F2, F3, F5, F7, F9, FGA

Molecular functions related to Disseminated Intravascular Coagulation according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1peptidase activityGO:00082339.8ADAMTS13, ELANE, F2, F9
2endopeptidase activityGO:00041759.6ELANE, F7, F9
3protease bindingGO:00020209.4ELANE, F3, SERPINC1, SERPINE1, SERPINF2
4calcium ion bindingGO:00055099.1ADAMTS13, F2, F7, F9, THBD
5receptor bindingGO:00051028.9F2, F7, FGA, PLAT, SERPINE1
6serine-type endopeptidase inhibitor activityGO:00048678.8SERPINC1, SERPINE1, SERPINF2, TFPI
7serine-type endopeptidase activityGO:00042528.2ELANE, F2, F3, F5, F7, F9

Sources for Disseminated Intravascular Coagulation

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet