Aliases & Classifications for Disuse Amblyopia

MalaCards integrated aliases for Disuse Amblyopia:

Name: Disuse Amblyopia 12 14
Stimulus Deprivation Amblyopia 69
Deprivation Amblyopia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10378
ICD10 32 H53.01
ICD9CM 34 368.02
SNOMED-CT 64 193638002 21457000
UMLS 69 C0152189

Summaries for Disuse Amblyopia

MalaCards based summary : Disuse Amblyopia, also known as stimulus deprivation amblyopia, is related to anisometropia and septopreoptic holoprosencephaly. An important gene associated with Disuse Amblyopia is PLXNA2 (Plexin A2), and among its related pathways/superpathways are Pathways in cancer and NRF2 pathway. Affiliated tissues include eye, and related phenotypes are behavior/neurological and cellular

Related Diseases for Disuse Amblyopia

Graphical network of the top 20 diseases related to Disuse Amblyopia:



Diseases related to Disuse Amblyopia

Symptoms & Phenotypes for Disuse Amblyopia

MGI Mouse Phenotypes related to Disuse Amblyopia:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.25 CHN1 CSAD FGF13 FGF2 FOS FOXA2
2 cellular MP:0005384 10.18 ATP7B CADM1 CHN1 FGF13 FGF2 FOS
3 growth/size/body region MP:0005378 10.11 ATP7B CADM1 CHN1 DPT FOS FOXA2
4 nervous system MP:0003631 10.1 ATP7B CADM1 CHN1 EPHA2 FGF13 FGF2
5 reproductive system MP:0005389 9.81 SHH ATP7B CADM1 CSAD FGF2 FOS
6 neoplasm MP:0002006 9.8 EPHA2 FGF2 FOS FOXA2 GRM1 SHH
7 skeleton MP:0005390 9.56 GRM1 SHH CHN1 EPHA2 FGF2 FOS
8 vision/eye MP:0005391 9.28 GLI2 GRM1 PLXNA2 SHH DPT EPHA2

Drugs & Therapeutics for Disuse Amblyopia

Search Clinical Trials , NIH Clinical Center for Disuse Amblyopia

Genetic Tests for Disuse Amblyopia

Anatomical Context for Disuse Amblyopia

MalaCards organs/tissues related to Disuse Amblyopia:

38
Eye

Publications for Disuse Amblyopia

Articles related to Disuse Amblyopia:

# Title Authors Year
1
Deprivation amblyopia and congenital hereditary cataract. ( 24138041 )
2013
2
Spectral-domain optical coherence tomography analysis in deprivational amblyopia: a pilot study with unilateral pediatric cataract patients. ( 24146271 )
2013
3
The effect of video game training on the vision of adults with bilateral deprivation amblyopia. ( 23193607 )
2012
4
Protection against deprivation amblyopia depends on relative not absolute daily binocular exposure. ( 21680647 )
2011

Variations for Disuse Amblyopia

Expression for Disuse Amblyopia

Search GEO for disease gene expression data for Disuse Amblyopia.

Pathways for Disuse Amblyopia

GO Terms for Disuse Amblyopia

Biological processes related to Disuse Amblyopia according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.91 FGF2 FOS FOXA2 GLI2 SHH
2 negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435 9.59 SDCBP SHH
3 dopaminergic neuron differentiation GO:0071542 9.58 FOXA2 SHH
4 ephrin receptor signaling pathway GO:0048013 9.58 CHN1 EPHA2 SDCBP
5 hindbrain development GO:0030902 9.57 GLI2 SHH
6 spinal cord motor neuron differentiation GO:0021522 9.56 GLI2 SHH
7 anatomical structure formation involved in morphogenesis GO:0048646 9.55 GLI2 SHH
8 osteoblast development GO:0002076 9.54 GLI2 SHH
9 cell fate specification GO:0001708 9.52 FOXA2 SHH
10 prostate gland development GO:0030850 9.49 GLI2 SHH
11 anatomical structure development GO:0048856 9.48 GLI2 SHH
12 embryonic morphogenesis GO:0048598 9.46 FGF2 SHH
13 dorsal/ventral neural tube patterning GO:0021904 9.43 GLI2 SHH
14 limb bud formation GO:0060174 9.37 PLXNA2 SHH
15 positive regulation of T cell differentiation in thymus GO:0033089 9.32 GLI2 SHH
16 spinal cord dorsal/ventral patterning GO:0021513 9.26 GLI2 SHH
17 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 9.16 GLI2 SHH
18 hindgut morphogenesis GO:0007442 8.96 GLI2 SHH
19 ventral midline development GO:0007418 8.62 GLI2 SHH
20 multicellular organism development GO:0007275 10.05 CADM1 EPHA2 FGF2 FOXA2 GLI2 SHH

Sources for Disuse Amblyopia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....