MCID: DVR002
MIFTS: 45

Diverticulitis malady

Summaries for Diverticulitis

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Diverticulitis is a common digestive disease which involves the formation of pouches (diverticula)... more...

MalaCards: Diverticulitis, also known as diverticulitis unspecified, is related to colorectal cancer and inflammatory bowel disease. An important gene associated with Diverticulitis is MMP13 (matrix metallopeptidase 13 (collagenase 3)). The drugs scopolamine and scopolamine hydrobromide and the compounds fosinopril and (4-aminophenyl)mercuric acetate have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and heart.

Aliases & Classifications for Diverticulitis

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 39NCIt, 56SNOMED-CT, 34MeSH
See all sources

Aliases & Descriptions:

diverticulitis 8 10 44 60
diverticulitis unspecified 8
diverticulitis nos 8


External Ids:

Disease Ontology8 DOID:7475
NCIt39 C26752
MeSH34 D004238

Related Diseases for Diverticulitis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Diverticulitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 100)
idRelated DiseaseScoreTop Affiliating Genes
1colorectal cancer30.1SERPINA1, MMP9, MMP13, MUC5AC
2inflammatory bowel disease29.9CRP, MUC5AC, MMP13, SERPINA1
3ulcerative colitis29.7CRP
4abdominal aortic aneurysm29.7MMP13, MMP9
5diverticulitis of colon10.8
6meckel's diverticulitis10.7
7appendicitis10.5
8peritonitis10.5
9colonic disease10.4
10colon cancer10.3
11duodenitis10.2
12obesity10.2
13thrombophlebitis10.2
14necrotizing fasciitis10.1
15fasciitis10.1
16williams syndrome10.1
17sigmoid disease10.1
18small intestine diverticulitis10.1
19crohn's disease10.0
20colon lymphoma10.0
21williams-beuren syndrome10.0
22morbid obesity10.0
23polycystic kidney disease10.0
24irritable bowel syndrome10.0
25endocarditis10.0
26hepatitis10.0
27kidney disease10.0
28lung cancer10.0
29schistosomiasis10.0
30liver cirrhosis10.0SERPINA1
31wegener's granulomatosis10.0SERPINA1
32rectal prolapse10.0APOLD1
33corneal ulcer10.0MUC5AC
34otitis media10.0MUC5AC
35proctitis10.0APOLD1
36pulmonary fibrosis10.0MMP9, MMP13
37synovitis10.0CRP, MMP13
38viral meningitis10.0CRP, SERPINA1
39eye disease10.0CRP
40bronchitis10.0CRP, SERPINA1
41kawasaki disease10.0CRP, MMP9
42periodontal disease10.0CRP, MMP9, MMP13
43pulmonary disease, chronic obstructive10.0CRP, MMP9, SERPINA1
44stomach cancer10.0SERPINA1, MMP9, MMP13, MUC5AC
45burns9.8
46paralytic ileus9.8
47perivascular epithelioid cell tumor9.8
48toxic megacolon9.8
49neuroendocrine carcinoma9.8
50cutis laxa9.8

Graphical network of the top 20 diseases related to Diverticulitis:



Diseases related to diverticulitis

Clinical Features for Diverticulitis

About this section

Drugs & Therapeutics for Diverticulitis

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Diverticulitis

Drug clinical trials:

Search ClinicalTrials for Diverticulitis

Search NIH Clinical Center for Diverticulitis

Search CenterWatch for Diverticulitis

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Diverticulitis

About this section

Anatomical Context for Diverticulitis

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Diverticulitis:

32
Colon, Small intestine, Heart, Liver, Lung, Kidney, Breast, Prostate, Testes, Appendix

Animal Models for Diverticulitis or affiliated genes

About this section

Publications for Diverticulitis

About this section
Sources:
50PubMed
See all sources

Articles related to Diverticulitis:

(show top 50)    (show all 563)
idTitleAuthorsYear
1
Sigmoid diverticulitis: a systematic review. (24430321)
2014
2
Minimally invasive surgery for diverticulitis. (23250639)
2013
3
Mandatory exploration is not necessary for patients with acute diverticulitis and free intraperitoneal air. (23609294)
2013
4
Preliminary experience with laparoscopic peritoneal lavage for complicated diverticulitis: a new algorithm for treatment? (23896252)
2013
5
Water enema multidetector CT technique and imaging of diverticulitis and chronic inflammatory bowel diseases. (23508934)
2013
6
Predictors of mortality after emergent surgery for acute colonic diverticulitis: analysis of National Surgical Quality Improvement Project data. (23354259)
2013
7
Acute right-sided colonic diverticulitis mimicking appendicitis: a report of two cases. (22855407)
2013
8
CT-colonography in the follow-up of acute diverticulitis: patient acceptance and diagnostic accuracy. (23834748)
2013
9
Triage of patients with acute diverticulitis: are some inpatients candidates for outpatient treatment? (23061533)
2013
10
Visceral obesity as a risk factor for left-sided diverticulitis in Japan: a multicenter retrospective study. (24073310)
2013
11
Caecal diverticulitis mimicking acute appendicitis. (24254275)
2013
12
Colouterine fistula caused by diverticulitis of the sigmoid colon. (23346512)
2012
13
Value of CT for acute left-colonic diverticulitis: the surgeon's view. (22572685)
2012
14
Complicated jejunal diverticulitis: a challenging diagnosis and difficult therapy. (22421718)
2012
15
Postpone your operation to a weekday, or look for an experienced surgeon: comment on "worse outcomes in patients undergoing urgent surgery for left-sided diverticulitis admitted on weekends vs weekdays". (22802062)
2012
16
Does a colonoscopy after acute diverticulitis affect its management?: a single center experience. (22186742)
2012
17
To operate or not to operate? Should functional outcomes after sigmoid colectomy for diverticulitis influence our decision making? (22156860)
2012
18
Perivascular epithelioid cell tumor of the ileum presenting as diverticulitis. (22953133)
2012
19
Another case of pediatric cecal diverticulitis. (23053597)
2012
20
Multicentre observational study of the natural history of left-sided acute diverticulitis (Br J Surg 2012; 99: 276-285) (Br J Surg 2012; 99: 285-286). (22473281)
2012
21
Perforated Meckel's diverticulitis on the mesenteric side: MDCT findings. (21479804)
2012
22
A multicenter randomized clinical trial of primary anastomosis or Hartmann's procedure for perforated left colonic diverticulitis with purulent or fecal peritonitis. (23095627)
2012
23
A rare case of perforated ileal diverticulitis. (21975432)
2012
24
Laparoscopic selective diverticulectomy of the colon as first treatment in acute complicated diverticulitis. (22808767)
2012
25
Clinical challenge: diverticulitis of third and fourth portion of the duodenum with perforation. (22449163)
2012
26
Recurrence and virulence of colonic diverticulitis in immunocompromised patients. (22444713)
2012
27
CT scans in diagnosing diverticulitis in the emergency department: is the radiation exposure warranted? (22228168)
2012
28
Correlation between complicated diverticulitis and visceral fat. (22022188)
2011
29
Co-morbidity and postsurgical outcome in patients with perforated sigmoid diverticulitis. (20676663)
2011
30
Trends in diverticulitis management in the United States from 2002 to 2007. (21173283)
2011
31
Generalized peritonitis due to perforated diverticulitis: Hartmann's procedure or primary anastomosis? (20949274)
2011
32
Is conservative treatment with antibiotics the correct strategy for management of right colonic diverticulitis?: a prospective study. (21980589)
2011
33
CT findings of misleading features of colonic diverticulitis. (22347935)
2011
34
Pneumosalpynx caused by colosalpingeal fistula secondary to acute colonic diverticulitis. (21243501)
2011
35
Treatment of right colonic diverticulitis: the role of nonoperative treatment. (21221240)
2010
36
Outpatient treatment of patients with uncomplicated acute diverticulitis. (19906059)
2010
37
Acute jejunal diverticulitis due to a foreign body. (20361851)
2010
38
Diverticulitis of the right colon: diagnostic pitfalls and current management. (21513635)
2010
39
Small bowel diverticulitis: an often overlooked cause of acute abdomen. (20697923)
2010
40
Right colonic diverticulitis: an uncommon disease in western countries. (20306911)
2010
41
Necrotizing fasciitis following laparoscopic left hemicolectomy for diverticulitis. (19916772)
2010
42
Jejunal Diverticulitis: A Rare Case of Severe Peritonitis. (21113287)
2010
43
Filiform polyposis associated with sigmoid diverticulitis in a patient without inflammatory bowel disease. (21122579)
2010
44
Perforated retroperitoneal retrofascial sigmoid diverticulitis as a cause of osteomyelitis and septic necrosis of the acetabulum and proximal femur. (20458856)
2010
45
Cecal diverticulitis. (19718390)
2009
46
Lessons learned from the analysis of 200 laparoscopic sigmoid resections for diverticulitis. (19390278)
2009
47
Intestinal perforation by saline total gut lavage in occult diverticulitis. (9826157)
1998
48
Epididymitis--an unusual presentation of colovesical fistula secondary to diverticulitis. Report of a case. (3391066)
1988
49
Pneumatosis cystoides intestinalis secondary to chronic jejunal diverticulitis. (523373)
1979
50
MECKEL'S DIVERTICULITIS WITH SECONDARY APPENDICITIS. (14272424)
1964

Genetic Variations for Diverticulitis

About this section

Expression for genes affiliated with Diverticulitis

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Diverticulitis

Search GEO for disease gene expression data for Diverticulitis.

Pathways for genes affiliated with Diverticulitis

About this section

Compounds for genes affiliated with Diverticulitis

About this section
Sources:
44Novoseek, 11DrugBank, 59Tocris Bioscience, 24HMDB
See all sources

Compounds related to Diverticulitis according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1fosinopril44 1111.1MMP9, CRP
2(4-aminophenyl)mercuric acetate4410.1MMP9, MMP13
3gabexate mesilate4410.1CRP, MMP9
4uk 3833675910.0MMP9, MMP13
5gm 6001599.9MMP9, MMP13
6p002449.8MMP9, MMP13, CRP
7ascorbic acid44 2410.8SERPINA1, PLOD2, MMP13, CRP
8fibrinogen449.7SERPINA1, MMP9, MMP13, CRP
9gi 254023x599.7MMP9, MMP13
10sb 20358044 5910.1CRP, MUC5AC, MMP13, MMP9
11paraffin448.9MUC5AC, MMP13, MMP9, SERPINA1

GO Terms for genes affiliated with Diverticulitis

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Diverticulitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to lead ionGO:01028810.0SERPINA1, CRP
2response to hypoxiaGO:0016668.8SERPINA1, PLOD2, CRP, APOLD1

Products for genes affiliated with Diverticulitis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Diverticulitis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet