MCID: DMN008

Dominant Cleft Palate malady

Summaries for Dominant Cleft Palate

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33MalaCards
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MalaCards: Dominant Cleft Palate is related to cleft palate. An important gene associated with Dominant Cleft Palate is TFAP2A (transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)). Affiliated tissues include skin.

Aliases & Classifications for Dominant Cleft Palate

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43NIH Rare Diseases
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Aliases & Descriptions:

dominant cleft palate 43


Related Diseases for Dominant Cleft Palate

Sources:
17GeneCards, 18GeneDecks
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Diseases in the cleft palate family:

dominant cleft palate cleft palate with ankyloglossia

Diseases related to Dominant Cleft Palate via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1cleft palate10.1

Clinical Features for Dominant Cleft Palate

Drugs & Therapeutics for Dominant Cleft Palate

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Dominant Cleft Palate

Drug clinical trials:

Search ClinicalTrials for Dominant Cleft Palate

Search NIH Clinical Center for Dominant Cleft Palate

Search CenterWatch for Dominant Cleft Palate

Genetic Tests for Dominant Cleft Palate

Anatomical Context for Dominant Cleft Palate

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33MalaCards
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MalaCards organs/tissues related to Dominant Cleft Palate:

33
Skin

Animal Models for Dominant Cleft Palate or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Dominant Cleft Palate

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51PubMed
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Articles related to Dominant Cleft Palate:

(show all 11)
idTitleAuthorsYear
1
A new autosomal dominant syndrome of distinctive face showing ptosis and prominent eyes associated with cleft palate, ear anomalies, and learning disability. (21834043)
2011
2
A second family with dominantly inherited isolated cleft palate. (20856025)
2010
3
Autosomal dominant syndrome of mental retardation, hypotelorism, and cleft palate resembling Schilbach-Rott syndrome. (19921646)
2009
4
Mandibulofacial syndrome with growth and mental retardation, microcephaly, ear anomalies with skin tags, and cleft palate in a mother and her son: autosomal dominant or X-linked syndrome? (19921636)
2009
5
Dominant coloboma-microphthalmos syndrome associated with sensorineural hearing loss, hematuria, and cleft lip/palate. (9382148)
1997
6
No evidence of linkage between the transforming growth factor-alpha gene in families with apparently autosomal dominant inheritance of cleft lip and palate. (1352355)
1992
7
Poikiloderma, alopecia, retrognathism and cleft palate: the PARC syndrome. Is this an undescribed dominantly inherited syndrome? (2242783)
1990
8
Ocular hypotelorism, submucosal cleft palate, and hypospadias: a new autosomal dominant syndrome. (3149147)
1988
9
The Gordon syndrome: autosomal dominant cleft palate, camptodactyly, and club feet. (7258227)
1981
10
The Stickler syndrome presenting as a dominantly inherited cleft palate and blindness. (1219119)
1975
11
Stickler syndrome. Presenting as a syndrome of cleft palate, myopia and blindness inherited as a dominant trait. (4218495)
1974

Genetic Variations for Dominant Cleft Palate

Expression for genes affiliated with Dominant Cleft Palate

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Dominant Cleft Palate

Search GEO for disease gene expression data for Dominant Cleft Palate.

Pathways for genes affiliated with Dominant Cleft Palate

Compounds for genes affiliated with Dominant Cleft Palate

GO Terms for genes affiliated with Dominant Cleft Palate

Products for genes affiliated with Dominant Cleft Palate

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Dominant Cleft Palate

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet