GWD
MCID: DRC001
MIFTS: 37

Dracunculiasis (GWD) malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Dracunculiasis

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Sources:
2CDC, 11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 32ICD9CM, 39MeSH, 40MESH via Orphanet, 45NCIt, 48NIH Rare Diseases, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Dracunculiasis:

Name: Dracunculiasis 11 48 54 2 39 13 68
Guinea Worm Disease 48 54 2
Parasitic Infection Caused by Dracunculus Medinensis 48
Infection by Dracunculus Medinensis 11
Guinea Worm Infection 48
 
Medina Worm Disease 54
Dracunculosis 54
Dracontiasis 11
Medinensis 54
Gwd 48

Characteristics:

Orphanet epidemiological data:

54
dracunculiasis:
Age of onset: All ages; Age of death: any age

Classifications:



External Ids:

Disease Ontology11 DOID:14418
ICD1030 B72
ICD9CM32 125.7
MeSH39 D004320
NCIt45 C84677
SNOMED-CT62 396334002, 48874008
Orphanet54 ORPHA231
UMLS via Orphanet69 C0013100
ICD10 via Orphanet31 B72
MESH via Orphanet40 D004320

Summaries for Dracunculiasis

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Disease Ontology:11 A parasitic helminthiasis infectious disease that involves parasitic infection by the larvae of the nematode Dracunculus medinensis, which are transmitted to humans by drinking water containing copepods infected with the larvae. The female, which contains larvae, burrows into the deeper connective tissues or adjacent to long bones or joints of the extremities. The worm emerges as a whitish filament in the center of a painful ulcer, accompanied by inflammation and frequently by secondary bacterial infection.

MalaCards based summary: Dracunculiasis, also known as guinea worm disease, is related to schistosomiasis and onchocerciasis, and has symptoms including Array, Array and Array. An important gene associated with Dracunculiasis is SETDB1 (SET Domain Bifurcated 1). The drug thiabendazole has been mentioned in the context of this disorder. Affiliated tissues include skin, bone and breast.

CDC:2 The program has made great strides from 3.5 million cases annually in the mid-1980s to 25 cases in 2016. Global eradication is within reach.

Wikipedia:71 Dracunculiasis, also called Guinea-worm disease (GWD), is an infection by the Guinea worm. A person... more...

Related Diseases for Dracunculiasis

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Diseases related to Dracunculiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
idRelated DiseaseScoreTop Affiliating Genes
1schistosomiasis10.0
2onchocerciasis9.9
3smallpox9.9
4trachoma9.8
5pleurisy9.8
6malaria9.7
7scurvy9.7
8trichuriasis9.7
9typhoid fever9.7
10yellow fever9.7
11filariasis9.7
12urethritis9.7
13dermatitis9.7
14ascariasis9.7
15poliomyelitis9.7
16muscular atrophy9.7
17hyperparathyroidism9.6HPGDS, ONECUT3, PPP1R14A, PRSS21
18abnormality of glucagon secretion8.3AVPR2, HM13, HPGDS, MANEA, ONECUT3, PPP1R14A

Graphical network of diseases related to Dracunculiasis:



Diseases related to dracunculiasis

Symptoms & Phenotypes for Dracunculiasis

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Human phenotypes related to Dracunculiasis:

 54 64 (show all 15)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 skin rash64 54 Very frequent (99-80%) HP:0000988
2 pruritus64 54 Very frequent (99-80%) HP:0000989
3 arthritis64 54 Frequent (79-30%) HP:0001369
4 flexion contracture64 54 Occasional (29-5%) HP:0001371
5 limitation of joint mobility64 54 Frequent (79-30%) HP:0001376
6 subcutaneous nodule64 54 Very frequent (99-80%) HP:0001482
7 diarrhea64 54 Very frequent (99-80%) HP:0002014
8 nausea and vomiting64 54 Very frequent (99-80%) HP:0002017
9 abnormal blistering of the skin64 54 Very frequent (99-80%) HP:0008066
10 low-grade fever64 54 Very frequent (99-80%) HP:0011134
11 immunologic hypersensitivity64 54 Frequent (79-30%) HP:0100326
12 cellulitis64 54 Frequent (79-30%) HP:0100658
13 gangrene64 54 Occasional (29-5%) HP:0100758
14 recurrent cutaneous abscess formation64 54 Frequent (79-30%) HP:0100838
15 skin ulcer64 54 Very frequent (99-80%) HP:0200042

Drugs & Therapeutics for Dracunculiasis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Dracunculiasis

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: dracunculiasis

Genetic Tests for Dracunculiasis

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Anatomical Context for Dracunculiasis

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MalaCards organs/tissues related to Dracunculiasis:

36
Skin, Bone, Breast, Testes, Spinal cord

Publications for Dracunculiasis

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Articles related to Dracunculiasis:

(show top 50)    (show all 323)
idTitleAuthorsYear
1
Dracunculiasis eradication: global surveillance summary, 2016. (28530374)
2017
2
The painting of St. Roch in the picture gallery of Bari (15th century): An ancient representation of dracunculiasis? (28189713)
2017
3
Smallpox and Dracunculiasis: The Scientific Value of Infectious Diseases That Have Been Eradicated or Targeted for Eradication. Is Schistosomiasis Next? (26741130)
2016
4
Progress Toward Global Eradication of Dracunculiasis -January 2015-June 2016. (27736840)
2016
5
Dracunculiasis eradication: global surveillance summary, 2015. (27132287)
2016
6
Dracunculiasis in oral and maxillofacial surgery. (27162746)
2016
7
Progress Toward Global Eradication of Dracunculiasis, January 2014-June 2015. (26492134)
2015
8
Monthly report on dracunculiasis cases, Januarya89December 2014. (25702332)
2015
9
Monthly report on dracunculiasis cases, Januarya89November 2014. (25671847)
2015
10
Monthly report on dracunculiasis cases, January-October 2015. (26685392)
2015
11
Monthly report on dracunculiasis cases, Januarya89 February 2015. (25958418)
2015
12
Monthly report on dracunculiasis cases, January-April 2015. (26027017)
2015
13
Monthly report on dracunculiasis cases, January- September 2015. (26591027)
2015
14
Monthly report on dracunculiasis cases, January-July 2015. (26454889)
2015
15
Dracunculiasis eradication: global surveillance summary, 2014. (25958417)
2015
16
Monthly report on dracunculiasis cases, January-May 2015. (26121769)
2015
17
Monthly report on dracunculiasis cases, January-June 2015. (26298884)
2015
18
Guinea worm (Dracunculiasis) eradication: update on progress and endgame challenges. (24699360)
2014
19
Progress toward global eradication of dracunculiasis--January 2013-June 2014. (25412061)
2014
20
Monthly report on dracunculiasis cases, Januarya89November 2013. (24446560)
2014
21
Monthly report on dracunculiasis cases, Januarya89October 2014. (25538996)
2014
22
The peculiar epidemiology of dracunculiasis in chad. (24277785)
2014
23
Monthly report on dracunculiasis cases, Januarya89May 2014. (25028755)
2014
24
Monthly report on dracunculiasis cases, Januarya89August 2014. (25313424)
2014
25
Monthly report on dracunculiasis cases, Januarya89July 2014. (25184187)
2014
26
Dracunculiasis eradication--global surveillance summary, 2013. (24864343)
2014
27
An experience with dracunculiasis in Melbourne, Australia. (25393260)
2014
28
Monthly report on dracunculiasis cases, January a89- April 2014. (24864344)
2014
29
Monthly report on dracunculiasis cases, Januarya89February 2014. (24707536)
2014
30
Monthly report on dracunculiasis cases, Januarya89June 2014. (25136722)
2014
31
Monthly report on dracunculiasis cases, January 2014. (24707516)
2014
32
Monthly report on dracunculiasis cases, Januarya89December 2013. (24707512)
2014
33
Monthly report on dracunculiasis cases, Januarya89November 2012. (23393705)
2013
34
Monthly report on dracunculiasis cases, January a89 February 2013. (23586140)
2013
35
Monthly report on dracunculiasis cases, Januarya89April 2013. (23807971)
2013
36
Monthly report on dracunculiasis cases, January a89- May 2013. (23980291)
2013
37
Dracunculiasis (guinea worm disease): eradication without a drug or a vaccine. (23798694)
2013
38
Dracunculiasis eradication a89 global surveillance summary, 2012. (23696981)
2013
39
Monthly report on dracunculiasis cases, January - July 2013. (24143843)
2013
40
Monthly report on dracunculiasis cases, January a89 August 2013. (24159669)
2013
41
Monthly report on dracunculiasis cases, Januarya89October 2013. (24436997)
2013
42
Monthly report on dracunculiasis cases, Januarya89December 2012. (23540052)
2013
43
Monthly report on dracunculiasis cases, Januarya89September 2013. (24319785)
2013
44
Progress toward global eradication of dracunculiasis--January 2012-June 2013. (24153313)
2013
45
Monthly report on dracunculiasis cases, Januarya89June 2013. (24040692)
2013
46
Monthly report on dracunculiasis cases, January a89 March 2013. (23696982)
2013
47
Dracunculiasis eradication: and now, South Sudan. (23843492)
2013
48
Monthly report on dracunculiasis cases, January 2013 a89 first month with zero cases. (23544240)
2013
49
Monthly report on dracunculiasis cases, Januarya89September 2012. (23139956)
2012
50
Dracunculiasis eradication--finishing the job before surprises arise. (22647809)
2012

Variations for Dracunculiasis

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Expression for genes affiliated with Dracunculiasis

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Search GEO for disease gene expression data for Dracunculiasis.

Pathways for genes affiliated with Dracunculiasis

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GO Terms for genes affiliated with Dracunculiasis

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Biological processes related to Dracunculiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein homotetramerizationGO:00512899.3HM13, SAMHD1

Sources for Dracunculiasis

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet