MCID: DRG003
MIFTS: 57

Drug Dependence malady

Summaries for Drug Dependence

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A substance dependence that involves the continued use of drugs despite despite problems related to use of the substance.

MalaCards: Drug Dependence is related to alcohol dependence and substance dependence. An important gene associated with Drug Dependence is OPRL1 (opiate receptor-like 1), and among its related pathways are Dopamine receptors and Enzymatic degradation of dopamine by COMT. The compounds bremazocine and dermorphin have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and breast, and related mouse phenotypes are adipose tissue and taste/olfaction.

Wikipedia:63 Substance dependence, commonly called drug addiction, is a compulsive need to use drugs in order to... more...

Aliases & Classifications for Drug Dependence

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8Disease Ontology, 44Novoseek, 60UMLS, 56SNOMED-CT, 27ICD9CM
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Aliases & Descriptions:

drug dependence 8 44 60


External Ids:

Disease Ontology8 DOID:9974
ICD9CM27 304.60, 304.6

Related Diseases for Drug Dependence

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17GeneCards, 18GeneDecks
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Diseases related to Drug Dependence via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 101)
idRelated DiseaseScoreTop Affiliating Genes
1alcohol dependence31.3OPRM1, CHRM2, MAOA, CNR1, ADH1A, ADH4
2substance dependence30.6PDYN, DRD2, DRD3, OPRM1, CNR1, SLC6A3
3cocaine dependence30.5DRD3, OPRK1, OPRM1, SLC6A3, SLC6A4, DRD2
4personality disorder30.4DRD3, MAOA, SLC6A3, SLC6A4, DRD2
5nicotine dependence30.3SLC6A4, CHRNA2, DRD2
6opiate dependence30.3OPRM1
7morphine dependence30.3OPRK1, OPRD1
8conduct disorder30.3DRD2, MAOA, SLC6A3, SLC6A4
9heroin dependence30.0DRD2
10anxiety disorder30.0SLC6A4, MAOA
11borderline personality disorder30.0MAOA, SLC6A4
12social phobia30.0DRD2, SLC6A4, MAOA
13obesity30.0CNR1, SLC6A3, DRD2, MAOA
14alcohol abuse30.0OPRM1, DRD2, SLC6A4, SLC6A3, DRD3
15anorexia nervosa29.8SLC6A4, CNR1, MAOA
16cocaine abuse29.8SLC6A4, OPRK1, SLC6A3, DRD2
17antisocial personality disorder29.8DRD2, MAOA, SLC6A4, SLC6A3
18obsessive-compulsive disorder29.8DRD2, PDYN, MAOA, SLC6A4, SLC6A3, DRD3
19substance abuse29.8OPRM1, SLC6A3, SLC6A4, ADH4, CNR1, DRD2
20drug addiction29.8SLC6A3, DARC, OPRM1, OPRD1, OPRK1, DRD3
21schizophrenia29.8PNOC, SLC6A4, PDYN, DRD2, DRD3, OPRK1
22alzheimer's disease29.8MAOA, CNR1, SLC6A3, OPRM1, OPRD1, PDYN
23dependent personality disorder10.3
24barbiturate dependence10.1
25cerebritis10.1
26hepatitis10.1
27hepatitis c10.0
28neonatal abstinence syndrome10.0
29post-traumatic stress disorder10.0
30hallucinogen dependence10.0
31thrombocytopenia10.0
32major depressive disorder10.0CHRM2
33neuroblastoma10.0OPRM1
34restless legs syndrome10.0DRD2
35hypertension10.0SLC6A4
36bulimia nervosa10.0SLC6A4, MAOA
37fibromyalgia10.0SLC6A4, PNOC
38cluster headache10.0PNOC
39panic disorder10.0SLC6A4, MAOA
40hepatic encephalopathy10.0MAOA
41pathological gambling10.0DRD3, DRD2, SLC6A3
42delusional disorder10.0DRD2
43obsessive-compulsive personality disorder10.0SLC6A4
44multiple system atrophy10.0SLC6A3, DRD2
45constipation10.0OPRM1, SLC6A4
46withdrawal disorder10.0OPRM1, CNR1, PDYN
47alcoholic psychosis10.0SLC6A4
48chronic fatigue syndrome10.0MAOA, SLC6A4
49schizoaffective disorder10.0DRD2, SLC6A4, DRD3
50liver cirrhosis10.0PNOC, CNR1

Graphical network of the top 20 diseases related to Drug Dependence:



Diseases related to drug dependence

Clinical Features for Drug Dependence

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Drugs & Therapeutics for Drug Dependence

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Drug Dependence

Drug clinical trials:

Search ClinicalTrials for Drug Dependence

Search NIH Clinical Center for Drug Dependence

Search CenterWatch for Drug Dependence

Genetic Tests for Drug Dependence

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Anatomical Context for Drug Dependence

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32MalaCards
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MalaCards organs/tissues related to Drug Dependence:

32
Brain, Testes, Breast, Prostate, Lung, Myeloid, Colon, T cells, Bone marrow, Liver, Smooth muscle, Cortex, Bone, Prefrontal cortex

Animal Models for Drug Dependence or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Drug Dependence:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537510.2CNR1, OPRM1, DRD3, DRD2, PDYN
2MP:00053949.9DRD2, CNR1, SLC6A3, ADH7
3MP:00107719.9PDYN, DRD2, OPRK1, OPRD1, OPRL1, OPRM1
4MP:00053869.7ADH7, PDYN, DRD2, DRD3, OPRK1, OPRD1
5MP:00053769.6OPRM1, OPRL1, OPRD1, DRD3, DRD2, PDYN
6MP:00036319.5PDYN, DRD2, DRD3, OPRD1, OPRL1, OPRM1

Publications for Drug Dependence

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Sources:
50PubMed
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Articles related to Drug Dependence:

(show top 50)    (show all 782)
idTitleAuthorsYear
1
The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence. (24189487)
2014
2
Problematic alcohol use in clients recovering from drug dependence--time to adjust our focus. (23668295)
2013
3
The effects of exogenous progesterone on drug craving and stress arousal in cocaine dependence: impact of gender and cue type. (23374328)
2013
4
How can we develop a more precise examination of the role of alcohol in recovery from drug dependence? (23668421)
2013
5
Auricular acupuncture for drug dependence: an open-label randomized investigation on clinical outcomes, health-related quality of life, and patient acceptability. (23981370)
2013
6
Is smoking associated with alcohol-drug dependence in patients with pain and chronic pain patients? An evidence-based structured review. (22845022)
2012
7
Ethnic differences in the effect of drug use and drug dependence on brief motivational interventions targeting alcohol use. (22578530)
2012
8
The obesity epidemic and food addiction: clinical similarities to drug dependence. (22641965)
2012
9
The nicotinic acetylcholine receptor partial agonist varenicline and the treatment of drug dependence: a review. (19959340)
2010
10
Involvement of the brain histaminergic system in addiction and addiction-related behaviors: a comprehensive review with emphasis on the potential therapeutic use of histaminergic compounds in drug dependence. (20638439)
2010
11
Genetics of drug dependence. (20373669)
2010
12
Pro-opiomelanocortin gene variation related to alcohol or drug dependence: evidence and replications across family- and population-based studies. (19217079)
2009
13
Insulin-dependent actions of pioglitazone in newly diagnosed, drug naA^ve patients with type 2 diabetes. (19367381)
2009
14
The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage: implications for therapy of drug resistant breast cancers. (19342873)
2009
15
Mechanism of UVA-dependent DNA damage induced by an antitumor drug dacarbazine in relation to its photogenotoxicity. (17710513)
2008
16
HIV-1 drug-resistance and drug-dependence. (17961213)
2007
17
Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3. (17470528)
2007
18
CNR1 variation modulates risk for drug and alcohol dependence. (17509535)
2007
19
The opioid system in alcohol and drug dependence: family-based association study. (17503481)
2007
20
Clozapine bioactivation induces dose-dependent, drug-specific toxicity of human bone marrow stromal cells: a potential in vitro system for the study of agranulocytosis. (16844094)
2006
21
Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence. (16476706)
2006
22
Central and peripheral interactions between endocannabinoids and steroids, and implications for drug dependence. (15953622)
2005
23
Co-occurring DSM-IV drug abuse in DSM-IV drug dependence: results from the National Epidemiologic Survey on Alcohol and Related Conditions. (16157234)
2005
24
Irradiation and various cytotoxic drugs enhance tyrosine phosphorylation and beta(1)-integrin clustering in human A549 lung cancer cells in a substratum-dependent manner in vitro. (14991204)
2004
25
The cytotoxicity of chemotherapy drugs varies in cervical cancer cells depending on the p53 status. (15640620)
2004
26
Treatment of drug dependence enters a new high technological era. (15500602)
2004
27
Neurological basis of drug dependence and its effects on the immune system. (14741438)
2004
28
Bcl-2 has differing effects on the sensitivity of breast cancer cells depending on the antineoplastic drug used. (12460791)
2002
29
Cellular mechanisms of striatum-dependent behavioral plasticity and drug addiction. (12420804)
2002
30
Drug dependence in a journal club. (10833975)
2000
31
Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation. (11015800)
2000
32
Drug dependence in a journal club. (10833976)
2000
33
Problems of drug dependence 1999: Proceedings of the 61st annual scientific meeting, the College on Problems of Drug Dependence, Inc. (11680410)
1999
34
Drug concentration-dependent expression of multidrug resistance-associated protein and P-glycoprotein in the doxorubicin-resistant acute myelogenous leukemia sublines. (10420992)
1999
35
Drug dependence during pregnancy. Effect of an on-site support group. (9777620)
1998
36
Homologies and differences in the action of drugs of abuse and a conventional reinforcer (food) on dopamine transmission: an interpretative framework of the mechanism of drug dependence. (9328062)
1998
37
Chronic morphine increases hippocampal acetylcholine release: possible relevance in drug dependence. (8790987)
1996
38
Alcohol & drug abuse. HIV infection and risky sexual behaviors among women in treatment for noninjection drug dependence. (8916235)
1996
39
College on Problems of Drug Dependence Policy on Administering Drugs with Abuse Potential in Human Research. (8957150)
1996
40
Desensitization and neurohumor modulation: a model of drug dependence II. (8871473)
1995
41
The tobacco habit as drug dependence. (1859907)
1991
42
Molecular mechanisms of memory and drug dependence. (1845561)
1991
43
The diagnosis of drug dependence by primary care providers. (2005475)
1991
44
Brief history of control, prevention and treatment of drug dependence in Japan. (2183987)
1990
45
Drug dependence: defining the issues. (2378300)
1990
46
Problems of drug dependence 1990. Proceedings of the 52nd annual meeting. The Committee on Problems of Drug Dependence, Inc. Richmond, Virginia, June 1990. (1875989)
1990
47
The acquired immunodeficiency syndrome: do drug dependence and ethnicity share a common pathway? (3136359)
1988
48
Alcohol and other drug dependence among latinos. (18750251)
1987
49
WHO Expert Committee on Drug Dependence. (3105184)
1987
50
Barbiturate dependence and drug preference. (7195034)
1981

Genetic Variations for Drug Dependence

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Expression for genes affiliated with Drug Dependence

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Drug Dependence

Search GEO for disease gene expression data for Drug Dependence.

Pathways for genes affiliated with Drug Dependence

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Sources:
53Reactome, 37NCBI BioSystems Database, 29KEGG, 12EMD Millipore, 49PharmGKB
See all sources

Pathways related to Drug Dependence according to GeneCards/GeneDecks:

(show all 18)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.4DRD2, DRD3
2
Hide members
10.3SLC6A3, MAOA
3
Hide members
10.3ADH6, ADH4
410.3DARC, CHRM2, DRD3
5
Hide members
10.2SLC6A3, MAOA, DRD2, PDYN
610.2PDYN, DRD2, MAOA, SLC6A3
7
Hide members
10.2OPRK1, OPRD1, OPRL1, OPRM1, DARC
8
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10.2DRD2, DRD3, CHRM2, MAOA, SLC6A4
9
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10.1ADH1A, ADH4, ADH6, ADH7
10
Hide members
10.1ADH1A, ADH4, ADH6, ADH7
11
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10.1ADH1A, ADH4, ADH6, ADH7
12
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10.1ADH1A, ADH4, ADH6, ADH7
13
Hide members
10.1ADH7, ADH6, ADH4, ADH1A
14
Hide members
10.1MAOA, ADH1A, ADH4, ADH6, ADH7
1510.1MAOA, ADH1A, ADH4, ADH6, ADH7
16
Hide members
10.0DRD2, DRD3, OPRM1, CHRM2, MAOA, CNR1
17
Hide members
9.8PDYN, DRD2, DRD3, OPRK1, OPRD1, OPRL1
18
Hide members
9.7PNOC, PDYN, DRD2, DRD3, OPRK1, OPRD1

Compounds for genes affiliated with Drug Dependence

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Sources:
44Novoseek, 28IUPHAR, 59Tocris Bioscience, 11DrugBank, 49PharmGKB, 24HMDB
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Compounds related to Drug Dependence according to GeneCards/GeneDecks:

(show top 50)    (show all 286)
idCompoundScoreTop Affiliating Genes
1bremazocine4410.6OPRK1, OPRM1, OPRL1, OPRD1
2dermorphin4410.6PDYN, OPRM1, OPRD1, OPRK1
3nalbzoh4410.6OPRD1, OPRM1, OPRK1, OPRL1, PNOC
4nalmefene44 2811.6OPRM1, OPRD1, OPRK1, PDYN
5norbinaltorphimine4410.6OPRD1, PNOC, OPRK1, OPRM1, PDYN
6[3h]diprenorphine4410.6OPRD1, OPRM1, PDYN, PNOC, OPRK1
7dpdpe28 44 5912.6OPRM1, OPRK1, OPRD1, PNOC, PDYN
8naltrindole44 2811.6PNOC, OPRM1, OPRD1, OPRK1
9damgo44 59 2812.5OPRL1, PDYN, PNOC, OPRK1, OPRD1, OPRM1
10etorphine44 28 1112.5PNOC, OPRK1, OPRL1, OPRD1, PDYN, OPRM1
11pentazocine44 1111.5OPRM1, OPRK1, PDYN, OPRD1
12buprenorphine44 28 1112.5OPRL1, OPRM1, PNOC, PDYN, OPRK1, OPRD1
13baclofen44 1111.5PNOC, CNR1, SLC6A3, OPRD1, OPRM1
14quinpirole44 2811.5DRD3, DRD2, PDYN, SLC6A3, CNR1
15sufentanil44 1111.5OPRM1, OPRD1, OPRK1, PNOC
16naltrexone44 49 28 1113.5OPRM1, OPRL1, PNOC, OPRD1, OPRK1
17naloxone44 49 28 1113.5OPRM1, CNR1, OPRD1, OPRK1, PNOC, PDYN
18amitriptyline44 49 28 1113.5SLC6A4, SLC6A3, CHRM2, OPRD1, MAOA, OPRK1
196-hydroxydopamine4410.5DRD2, DRD3, OPRM1, MAOA, SLC6A3, PDYN
20tyramine44 28 2412.4OPRD1, SLC6A4, OPRM1, MAOA, SLC6A3
21capsaicin44 2811.4PDYN, OPRK1, OPRM1, OPRD1, PNOC, MAOA
22methadone44 49 1112.4PDYN, DRD2, OPRK1, OPRD1, OPRM1
23clozapine44 28 49 1113.4DRD2, DRD3, OPRK1, OPRD1, CHRM2, SLC6A3
24methamphetamine44 49 1112.4DRD2, PDYN, DRD3, OPRD1, OPRM1, MAOA
25nmda44 2811.4OPRD1, OPRK1, PDYN, OPRM1, MAOA, SLC6A3
26amphetamine44 1111.4SLC6A4, CNR1, MAOA, OPRK1, DRD2, PDYN
27indole4410.4OPRD1, SLC6A4, PNOC, MAOA, OPRK1
28levodopa44 1111.4OPRM1, DRD3, MAOA, CNR1, SLC6A3, PDYN
29d amphetamine4410.4SLC6A3, MAOA, DRD2, SLC6A4
30Tapentadol1110.4OPRM1, SLC6A4, OPRD1, OPRK1
31bupropion44 49 11 2413.4SLC6A4, DRD2, CNR1, SLC6A3, DRD3
32heroin44 49 1112.4PDYN, DRD2, DRD3, OPRK1, OPRD1, OPRM1
33morphine44 49 28 1113.4PDYN, DRD2, OPRL1, OPRM1, CNR1, PNOC
34paroxetine44 49 28 1113.3DRD3, SLC6A4, SLC6A3, MAOA, CHRM2
35acetylcholine44 49 28 11 2414.3PDYN, PNOC, SLC6A3, CNR1, OPRM1, OPRD1
36tramadol44 49 1112.3OPRD1, OPRK1, OPRM1, SLC6A4
375-hydroxytryptamine4410.3SLC6A3, PNOC, CNR1, MAOA, CHRM2, OPRL1
38choline44 11 2412.2CHRM2, ADH6, SLC6A3, SLC6A4, ADH1A, MAOA
39opiate4410.2OPRD1, OPRL1, OPRM1, CHRM2, PNOC, DRD3
40cocaine44 1111.2PDYN, DRD2, DRD3, OPRK1, OPRD1, OPRM1
41gaba4410.2SLC6A4, SLC6A3, PNOC, CNR1, MAOA, CHRM2
42dopamine44 28 11 2413.2SLC6A4, PNOC, CNR1, MAOA, OPRD1, OPRK1
43glutamate4410.1DRD3, SLC6A4, SLC6A3, PNOC, CNR1, PDYN
44desipramine44 49 1112.1CHRM2, SLC6A4, MAOA, CNR1, SLC6A3
45mptp4410.1DRD2, DRD3, MAOA, SLC6A3, SLC6A4
46nicotine44 49 28 1113.1SLC6A4, SLC6A3, CNR1, MAOA, CHRM2, CHRNA2
47gtp44 2811.1DRD3, OPRK1, PNOC, CHRM2, OPRM1, OPRL1
48norepinephrine44 11 2412.1PDYN, SLC6A4, SLC6A3, PNOC, CNR1, MAOA
49fluoxetine49 44 28 1113.0SLC6A4, SLC6A3, CNR1, DRD2, MAOA
50piperazine44 1110.9DRD3, DRD2, OPRM1, SLC6A3

GO Terms for genes affiliated with Drug Dependence

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Sources:
16Gene Ontology
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Cellular components related to Drug Dependence according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1plasma membraneGO:0058869.7OPRL1, OPRD1, OPRK1, DRD3, DRD2, OPRM1
2integral to plasma membraneGO:0058879.6SLC6A4, DRD2, DRD3, OPRK1, OPRD1, OPRL1

Biological processes related to Drug Dependence according to GeneCards/GeneDecks:

(show all 45)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of dopamine receptor signaling pathwayGO:06016010.7DRD2, DRD3
2response to histamineGO:03477610.7DRD2, DRD3
3regulation of dopamine uptake involved in synaptic transmissionGO:05158410.7DRD2, DRD3
4opioid receptor signaling pathwayGO:03800310.7OPRK1, OPRD1
5adenylate cyclase-inhibiting dopamine receptor signaling pathwayGO:00719510.7DRD3, DRD2
6dopamine catabolic processGO:04242010.7MAOA, SLC6A3
7regulation of cAMP metabolic processGO:03081410.7DRD3, DRD2
8response to morphineGO:04327810.7CNR1, DRD3, DRD2
9prepulse inhibitionGO:06013410.7SLC6A3, DRD3, DRD2
10negative regulation of blood pressureGO:04577610.7CNR1, DRD3, DRD2
11negative regulation of adenylate cyclase activityGO:00719410.7OPRM1, DRD3, DRD2
12response to nicotineGO:03509410.7DRD2, CNR1, SLC6A3
13phospholipase C-activating G-protein coupled receptor signaling pathwayGO:00720010.7OPRM1, OPRD1, OPRK1
14monoamine transportGO:01584410.7SLC6A3, SLC6A4
15adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayGO:00719310.7OPRM1, OPRL1, OPRD1, OPRK1
16adenohypophysis developmentGO:02198410.7SLC6A3, DRD2
17reduction of cytosolic calcium ion concentrationGO:05148110.7OPRM1, DRD2
18sensory perceptionGO:00760010.7PNOC, OPRM1, OPRL1, OPRK1
19sensory perception of painGO:01923310.7OPRK1, OPRM1, CNR1
20behavioral response to ethanolGO:04814910.7DRD2, OPRM1
21response to cocaineGO:04222010.7DRD2, DRD3, CNR1, SLC6A3
22behaviorGO:00761010.7OPRK1, OPRM1, MAOA, CNR1
23regulation of synaptic transmission, GABAergicGO:03222810.7DRD2, CNR1
24G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerGO:00718710.7OPRD1, OPRM1, CHRM2, CNR1
25alcohol metabolic processGO:00606610.6ADH1A, ADH4
26dopamine metabolic processGO:04241710.6DRD2, DRD3
27regulation of dopamine secretionGO:01405910.6DRD2, DRD3
28adenylate cyclase-activating dopamine receptor signaling pathwayGO:00719110.6DRD3, OPRM1
29negative regulation of protein secretionGO:05070910.6DRD2, DRD3
30locomotory behaviorGO:00762610.6SLC6A3, OPRM1, OPRK1, DRD3, DRD2
31behavioral response to cocaineGO:04814810.6DRD2, DRD3
32ethanol oxidationGO:00606910.6ADH1A, ADH4, ADH6, ADH7
33response to iron ionGO:01003910.6DRD2, SLC6A3
34G-protein coupled receptor internalizationGO:00203110.6DRD2, DRD3
35response to ethanolGO:04547110.6ADH7, ADH6, SLC6A3, CNR1, DRD3
36synaptic transmission, dopaminergicGO:00196310.5DRD2, DRD3
37xenobiotic metabolic processGO:00680510.5MAOA, ADH1A, ADH4, ADH6, ADH7
38synaptic transmissionGO:00726810.5PDYN, OPRK1, CHRNA2, MAOA, PNOC, SLC6A3
39arachidonic acid secretionGO:05048210.4DRD2, DRD3
40neuropeptide signaling pathwayGO:00721810.4PNOC, OPRD1, PDYN
41response to drugGO:04249310.4DRD2, DRD3, SLC6A3, SLC6A4
42positive regulation of renal sodium excretionGO:03581510.4DRD2, DRD3
43retinol metabolic processGO:04257210.3ADH7, ADH4
44circadian regulation of gene expressionGO:03292210.3DRD2, DRD3
45neurotransmitter biosynthetic processGO:04213610.0SLC6A3, MAOA

Molecular functions related to Drug Dependence according to GeneCards/GeneDecks:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1dopamine bindingGO:03524010.4SLC6A3, DRD3, DRD2
2dopamine neurotransmitter receptor activity, coupled via Gi/GoGO:00159110.4DRD3, DRD2
3alcohol dehydrogenase activity, zinc-dependentGO:00402410.4ADH1A, ADH4, ADH7
4alcohol dehydrogenase (NAD) activityGO:00402210.3ADH7, ADH6, ADH4, ADH1A
5drug bindingGO:00814410.3DRD2, DRD3, CNR1, SLC6A3
6monoamine transmembrane transporter activityGO:00850410.3SLC6A3, SLC6A4
7retinol dehydrogenase activityGO:00474510.3ADH7, ADH4
8opioid peptide activityGO:00151510.2PDYN, PNOC
9retinol bindingGO:01984110.0ADH7, ADH4

Products for genes affiliated with Drug Dependence

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Sources for Drug Dependence

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet