MCID: DRG002
MIFTS: 49

Drug-Induced Hepatitis malady

Summaries for Drug-Induced Hepatitis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. more...

MalaCards: Drug-Induced Hepatitis, also known as hepatitis, chronic, drug-induced, is related to hepatitis and tuberculosis. An important gene associated with Drug-Induced Hepatitis is NAT2 (N-acetyltransferase 2 (arylamine N-acetyltransferase)), and among its related pathways are Acetylation and Arylamine metabolism. The compounds benzidine and trichloroethylene have been mentioned in the context of this disorder. Affiliated tissues include liver, testes and t cells, and related mouse phenotype homeostasis/metabolism.

Aliases & Classifications for Drug-Induced Hepatitis

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8Disease Ontology, 60UMLS, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

drug-induced hepatitis 8
hepatitis, chronic, drug-induced 60
drug-induced chronic hepatitis 8
hepatitis, drug-induced 60


External Ids:

Disease Ontology8 DOID:2044
SNOMED-CT56 235889003
MeSH34 D056487

Related Diseases for Drug-Induced Hepatitis

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17GeneCards, 18GeneDecks
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Diseases related to Drug-Induced Hepatitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 144)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis31.5GPT, SLC17A5
2tuberculosis30.7CP, NAT2, CYP2E1
3autoimmune hepatitis30.5UGT1A1, CYP2C9, CYP2D6, GPT, SLC17A5, GSTT1
4pulmonary tuberculosis30.3CP, NAT2, CAT
5psoriasis30.1NAT2
6hyperinsulinism30.0GHR, GLUD1
7melanoma30.0GSTT1, CP, GHR, CAT
8hepatitis a10.7
9hepatic tuberculosis10.5
10granulomatous hepatitis10.2
11renal tuberculosis10.1
12alcoholic hepatitis10.1
13meningitis10.1
14multiple myeloma10.1
15myeloma10.1
16familial adenomatous polyposis10.0NAT2
17lupus erythematosus10.0NAT2
18substance abuse10.0CYP2E1
19esophageal cancer10.0CYP2E1
20malignant mesothelioma10.0NAT2
21alpha thalassemia10.0UGT1A1
22motor neuron disease10.0GSTT1
23ovarian cancer10.0GSTT1
24coronary heart disease10.0GSTT1
25schistosomiasis10.0GSTM1
26crigler-najjar syndrome10.0UGT1A1
27sickle cell disease10.0UGT1A1
28parkinson's disease10.0CYP2D6
29pneumonia10.0GSTM1
30essential hypertension10.0CYP2D6
31primary open angle glaucoma10.0GSTM1
32peptic ulcer10.0CYP2C19
33hemochromatosis10.0CP
34neonatal jaundice10.0UGT1A1, UGT1A6
35atopy10.0GSTT1, NAT2
36diarrhea10.0UGT1A1, UGT1A6
37pancreatic cancer10.0NAT2, NAT1
38leukoplakia10.0GSTM1, GSTT1
39cervical cancer10.0GSTT1, GSTM1
40kernicterus10.0UGT1A1, UGT1A6
41myocardial infarction10.0GSTT1, CYP2C9
42thromboembolism10.0CYP2C9
43deficiency anemia10.0GSTM1, CP
44thyroid cancer10.0GSTT1, GSTM1
45cholecystitis10.0GPT
46sarcoma10.0GSTM1
47asbestosis10.0GSTT1, GSTM1
48diabetic retinopathy10.0SORD
49cleft palate10.0GSTM1, NAT1
50pancreatitis10.0CYP2E1, SLC17A5

Graphical network of the top 20 diseases related to Drug-Induced Hepatitis:



Diseases related to drug-induced hepatitis

Clinical Features for Drug-Induced Hepatitis

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Drugs & Therapeutics for Drug-Induced Hepatitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Drug-Induced Hepatitis

Drug clinical trials:

Search ClinicalTrials for Drug-Induced Hepatitis

Search NIH Clinical Center for Drug-Induced Hepatitis

Search CenterWatch for Drug-Induced Hepatitis

Genetic Tests for Drug-Induced Hepatitis

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Anatomical Context for Drug-Induced Hepatitis

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Sources:
30LifeMap Discovery™, 32MalaCards
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MalaCards organs/tissues related to Drug-Induced Hepatitis:

32
Liver, Testes, T cells

LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine

Cells/anatomical compartments in embryo or adult related to Drug-Induced Hepatitis:
id TissueAnatomical CompartmentCell Relevance
1 LiverLiver LobuleHepatocytes Affected by disease

Animal Models for Drug-Induced Hepatitis or affiliated genes

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Sources:
36MGI
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MGI Mouse Phenotypes related to Drug-Induced Hepatitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.5GSTT1, SORD, GHR, GLUD1, CYP2E1, NAT1

Publications for Drug-Induced Hepatitis

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Sources:
50PubMed
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Articles related to Drug-Induced Hepatitis:

(show top 50)    (show all 111)
idTitleAuthorsYear
1
Drug-induced lupus and autoimmune hepatitis secondary to infliximab for psoriasis. (23651182)
2014
2
The impact of obesity and metabolic syndrome on chronic hepatitis B and drug-induced liver disease. (24274872)
2014
3
Seroprotection after hepatitis a vaccination in patients with drug-induced immunosuppression. (23992569)
2013
4
No impact of interleukin-28B polymorphisms on spontaneous or drug-induced hepatitis delta virus clearance. (24387833)
2013
5
Drug-induced acute liver injury mimicking autoimmune hepatitis after intake of dietary supplements containing glucosamine and chondroitin sulfate. (23391366)
2013
6
Anti-tuberculosis drug-induced hepatitis in renal transplant patient with pulmonary and extra pulmonary tuberculosis. (23960791)
2012
7
A Case of Drug-Induced Hepatitis due to Bortezomib in Multiple Myeloma. (22916049)
2012
8
Histological discrimination between autoimmune hepatitis and drug-induced liver injury. (22038865)
2012
9
A rare cause of drug-induced hepatitis in an immunocompromised patient and the role of glutathione. (22993667)
2012
10
Drug induced liver injury and its relationship to autoimmune hepatitis. (21396413)
2011
11
Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury. (21855518)
2011
12
Drug-induced autoimmune-like hepatitis: a case of chronic course after drug withdrawal. (21698369)
2011
13
The use of liver biopsy evaluation in discrimination of idiopathic autoimmune hepatitis versus drug-induced liver injury. (21674554)
2011
14
A Case of Drug-Induced Hepatitis due to Lenalidomide. (21552449)
2011
15
Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients. (22012226)
2011
16
Recurrent drug-induced liver injury (DILI) with different drugs in the Spanish Registry: the dilemma of the relationship to autoimmune hepatitis. (21338638)
2011
17
Incidence, clinical and epidemiological risk factors, and outcome of drug-induced hepatitis due to antituberculous agents in new tuberculosis cases. (19535968)
2010
18
Drug-induced hepatitis and lupus during infliximab treatment for psoriasis: case report and literature review. (20338127)
2010
19
Zhixue capsule caused seven cases of drug induced hepatitis. (20698229)
2010
20
Drug-induced autoimmune hepatitis caused by anti-tumor necrosis factor I+ agents. (20715094)
2010
21
Genetic polymorphisms of drug-metabolizing enzymes and anti-TB drug-induced hepatitis. (19891553)
2009
22
Drug-induced hepatotoxicity caused by anti-tuberculosis drugs in tuberculosis patients complicated with chronic hepatitis]. (18283910)
2008
23
Determining the relation between N-acetyltransferase-2 acetylator phenotype and antituberculosis drug induced hepatitis by molecular biologic tests. (18330759)
2008
24
Drug-induced hepatitis superimposed on the presence of anti-SLA antibody: a case report. (18226219)
2008
25
Prevalence and risk factors of anti-tuberculosis drug-induced hepatitis in Malaysia. (18830542)
2008
26
Drug-induced hepatitis - morphological and ultrastructural aspects. (18060200)
2007
27
Intestinal and hepatic CYP3A4 catalyze hydroxylation of 1alpha,25-dihydroxyvitamin D(3): implications for drug-induced osteomalacia. (16207822)
2006
28
Drug-induced hepatitis in a patient with malignant melanoma treated with interferon alfa 2b adjuvantly who had been administered gemfibrozil in therapy. (16645237)
2006
29
Drug-induced hepatitis with saquinavir/ritonavir + rifampin. (15828118)
2005
30
Clinical evaluation of drug-induced hepatitis. (15982181)
2005
31
Drug-induced hepatitis, drug-induced autoimmunity or classical autoimmune hepatitis: how can we differentiate? (15492907)
2004
32
Antituberculosis drug-induced hepatitis: risk factors, prevention and management. (15332488)
2003
33
Drug-induced hepatitis with autoimmune features during minocycline therapy. (12583618)
2003
34
Drug-induced hepatitis due to repeated use of hair dye. (14686750)
2003
35
Dramatic increase in bilirubin after ERCP - pethidine as a possible cause of drug-induced hepatitis. (14661125)
2003
36
Effects of the enterosorbent SUMS-1 on isoniazid pharmacokinetics and lipid peroxidation in patients with pulmonary tuberculosis and drug-induced hepatic lesions]. (11508231)
2001
37
Rapid improvement of icterus and pruritus by the oral administration of colestimide in two cases of drug-induced hepatitis. (11757763)
2001
38
Immunoallergic drug-induced hepatitis: lessons from halothane. (9138123)
1997
39
Plasma membrane cytochromes P450 as neoantigens and autoimmune targets in drug-induced hepatitis. (9138125)
1997
40
Role of reactive metabolites in drug-induced hepatitis. (8551007)
1995
41
Drug-specific T cells derived from patients with drug-induced allergic hepatitis. (1378078)
1992
42
Drug induced hepatitis. (1784106)
1991
43
Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug. (3540968)
1987
44
Drug-induced hepatitis associated with anticytoplasmic organelle autoantibodies. (4029887)
1985
45
Experience with immunological tests in drug-induced hepatitis. (7032097)
1981
46
Drug-induced granulomatous hepatitis. (7453131)
1981
47
Clinical aspects of drug-induced hepatitis. (277090)
1978
48
Drug induced interstitial nephritis, hepatitis and exfoliative dermatitis. (139882)
1976
49
Drug-induced hepatitis? (5094791)
1971
50
Recognition, prevention, and treatment of drug-induced hepatitis. (5766633)
1969

Genetic Variations for Drug-Induced Hepatitis

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Expression for genes affiliated with Drug-Induced Hepatitis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Drug-Induced Hepatitis

Search GEO for disease gene expression data for Drug-Induced Hepatitis.

Pathways for genes affiliated with Drug-Induced Hepatitis

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Sources:
53Reactome, 37NCBI BioSystems Database, 49PharmGKB, 29KEGG, 12EMD Millipore
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Pathways related to Drug-Induced Hepatitis according to GeneCards/GeneDecks:

(show all 32)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.1NAT2, NAT1
210.1NAT2, NAT1
310.1GSTM1, GSTT1
410.1GSTT1, GSTM1
5
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10.0CYP2D6, UGT1A1
6
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10.0CYP2E1, CAT
7
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9.9UGT1A3, UGT1A1, UGT1A6
89.9NAT1, NAT2, GSTM1
99.8UGT1A6, UGT1A3, CYP2C9
10
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9.8CYP2C9, CYP2E1, CYP2C19
119.8CYP2C19, CYP2E1, CYP2C9
12
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9.7CYP2C19, CYP2C9, UGT1A6
13
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9.7UGT1A6, UGT1A1, UGT1A3, GSTM1
14
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9.7CYP2C19, CYP2D6, CYP2C9
15
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9.7CYP2C19, CYP2D6, CYP2C9
16
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9.6CYP2C9, CYP2E1, NAT1, NAT2
17
Naphthalene metabolism
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9.6CYP2C9, CYP2E1, GSTM1, GSTT1
189.6CYP2C19, CYP2C9, GHR
19
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9.5UGT1A6, UGT1A1, UGT1A3, NAT1, NAT2
20
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9.5CYP2C9, CYP2D6, CYP2E1, CYP2C19
21
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9.5CYP2C9, CYP2D6, CYP2E1, CYP2C19
22
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9.5UGT1A1, CYP2C9, CYP2D6, CYP2C19
23
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9.5UGT1A1, CYP2C9, CYP2D6, CYP2C19
24
Retinol metabolism
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9.3UGT1A3, CYP2C9, CYP2D6, CYP2E1, CYP2C19
25
Acetaminophen metabolism
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9.3UGT1A6, UGT1A1, UGT1A3, CYP2D6, CYP2E1, NAT2
26
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9.3UGT1A1, UGT1A3, CYP2C9, CYP2D6, CYP2C19
27
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9.1UGT1A6, UGT1A1, CYP2C9, CYP2D6, CYP2E1, CYP2C19
28
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9.0UGT1A1, UGT1A3, CYP2C9, CYP2D6, CYP2E1, CYP2C19
29
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8.9NAT1, NAT2, B3GAT2, GPT, GSTM1, GSTT1
30
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8.1GSTT1, UGT1A6, GSTM1, NAT2, NAT1, CYP2C19
31
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8.1NAT2, NAT1, CYP2C19, CYP2E1, CYP2D6, CYP2C9
32
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7.9CAT, SORD, UGT1A6, UGT1A1, UGT1A3, GLUD1

Compounds for genes affiliated with Drug-Induced Hepatitis

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Sources:
44Novoseek, 11DrugBank, 49PharmGKB, 28IUPHAR, 24HMDB, 2BitterDB, 59Tocris Bioscience
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Compounds related to Drug-Induced Hepatitis according to GeneCards/GeneDecks:

(show top 50)    (show all 421)
idCompoundScoreTop Affiliating Genes
1benzidine449.8UGT1A1, GSTM1, NAT2, UGT1A6, GSTT1
2trichloroethylene449.8GSTT1, GSTM1, GPT, NAT2, CYP2E1
3Sulfanilamide119.8CYP2D6, CYP2E1, CYP2C19, CYP2C9
4mephenytoin44 49 1111.7CYP2C19, NAT2, CYP2C9, CYP2D6, CYP2E1
5flunitrazepam44 28 1111.7CYP2E1, CYP2C9, UGT1A1, UGT1A3, CYP2C19
6gsts449.6GSTM1, GSTT1, CYP2E1, CYP2D6, NAT2, NAT1
7Trabectedin119.6CYP2D6, CYP2C9, CYP2C19, CYP2E1
8p-nitrophenol44 1110.6CYP2E1, UGT1A6, CYP2D6, CYP2C9, UGT1A3, UGT1A1
9arylamine449.6GSTT1, NAT2, CYP2D6, CYP2C19, GSTM1, NAT1
10thiopurine449.6CYP2C9, CYP2D6, NAT2, UGT1A1, CYP2C19
11debrisoquine449.6CYP2C9, CYP2D6, CYP2E1, CYP2C19, NAT2, GSTM1
12rifampin49 1110.6CYP2C9, UGT1A1, CYP2E1, CYP2C19, NAT1, NAT2
13cotinine44 2410.5GSTT1, CYP2D6, UGT1A3, UGT1A1, UGT1A6, GSTM1
14benzo(a)pyrene449.5GSTT1, UGT1A6, UGT1A1, CYP2C9, NAT2, GSTM1
15paraxanthine44 2410.5CYP2C9, NAT1, CYP2C19, CYP2E1, NAT2, CYP2D6
16dapsone2 44 49 1112.5CYP2C9, CYP2D6, CYP2E1, CYP2C19, NAT1, NAT2
17vitamin a44 11 2411.5CP, NAT2, GHR, CAT, CYP2E1
18Dexfenfluramine119.5CYP2D6, CYP2C9, CYP2C19, CYP2E1
19beta-naphthoflavone44 1110.5CYP2C19, CYP2C9, CYP2D6, CYP2E1, UGT1A6, UGT1A1
20tolbutamide44 49 28 1112.5CYP2C9, CYP2D6, CYP2E1, CYP2C19, NAT2, GLUD1
21chlorzoxazone44 28 1111.4CYP2E1, CYP2C19, SLC17A5, CYP2C9, CYP2D6, NAT2
22antipyrine44 1110.4CYP2D6, SLC17A5, CYP2C19, CYP2E1, CYP2C9
23buprenorphine44 28 1111.4UGT1A3, CYP2C19, CYP2D6, CYP2C9, SLC17A5, UGT1A1
24propofol44 49 1111.4CYP2C9, CYP2C19, UGT1A6, CYP2E1, CYP2D6, UGT1A3
25aflatoxin b144 2410.4SLC17A5, GSTT1, GSTM1, NAT2, NAT1
26codeine44 49 28 11 2413.4UGT1A3, UGT1A6, CYP2C9, CYP2D6, UGT1A1, CYP2C19
27diclofenac44 28 49 1112.4UGT1A1, CYP2D6, UGT1A6, UGT1A3, CYP2C9, CYP2E1
28imipramine44 49 28 11 2413.3CYP2C19, UGT1A6, CYP2E1, CYP2D6, CYP2C9, UGT1A3
29estrone44 28 11 2412.3CYP2C19, CYP2E1, CYP2D6, CYP2C9, UGT1A3, UGT1A1
30fluvastatin44 49 28 1112.2CYP2C9, CYP2C19, UGT1A1, GPT, UGT1A3, CYP2D6
31phenytoin44 49 28 1112.2CYP2C19, SLC17A5, CP, CYP2C9, UGT1A1, CYP2D6
32uridine diphosphate449.2CYP2C19, CYP2E1, CYP2D6, CYP2C9, UGT1A3, UGT1A1
33betacarotene449.2GSTM1, NAT2, CYP2E1, CP, CAT, SLC17A5
34hydrocarbons449.1CYP2C9, NAT2, GSTT1, GSTM1, UGT1A1
35selegiline44 1110.1CYP2D6, CYP2C9, CAT, CYP2E1, CYP2C19
36oxygen44 2410.1GHR, CYP2D6, CYP2C19, BCL2L15, GSTM1, CYP2C9
37troglitazone44 28 59 1112.0CYP2C19, CYP2C9, SLC17A5, UGT1A1, UGT1A3, UGT1A6
38acetaminophen44 2 49 11 2413.0CYP2C9, CYP2E1, CYP2C19, NAT2, GPT, SLC17A5
39atorvastatin44 49 28 11 2413.0CYP2C19, CYP2D6, GPT, SLC17A5, CYP2C9, UGT1A3
40tamoxifen44 49 28 1112.0SLC17A5, CYP2C9, UGT1A6, UGT1A1, UGT1A3, CYP2D6
41malondialdehyde449.0GPT, GSTT1, GSTM1, CP, SLC17A5, CAT
42epoxide449.0NAT2, NAT1, CYP2C19, CYP2E1, CYP2D6, CYP2C9
43phenobarbital44 28 1110.9CP, SLC17A5, GPT, CYP2E1, CYP2C19, GSTM1
44simvastatin44 49 59 28 11 2413.9CYP2D6, CYP2C9, UGT1A3, UGT1A1, SLC17A5, GPT
45rifampicin44 28 5910.8SLC17A5, GPT, CYP2C9, UGT1A1, UGT1A6, CYP2D6
46nicotine44 49 28 1111.7UGT1A3, UGT1A1, UGT1A6, CYP2D6, CYP2C19, CYP2E1
47valproic acid44 49 11 2411.5UGT1A6, UGT1A1, UGT1A3, CYP2D6, CYP2C19, CP
48isoniazid49 44 1110.2GSTT1, GSTM1, SLC17A5, NAT1, CYP2C19, CYP2E1
49creatinine448.0CYP2E1, CP, SLC17A5, GSTT1, GSTM1, SORD
50testosterone44 59 11 2410.8CP, SLC17A5, CYP2C19, CYP2E1, SORD, UGT1A6

GO Terms for genes affiliated with Drug-Induced Hepatitis

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Sources:
16Gene Ontology
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Cellular components related to Drug-Induced Hepatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1endoplasmic reticulum membraneGO:0057898.9CYP2C19, CYP2E1, CYP2D6, CYP2C9, UGT1A3, UGT1A1

Biological processes related to Drug-Induced Hepatitis according to GeneCards/GeneDecks:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1xenobiotic glucuronidationGO:05269710.3UGT1A1, UGT1A3
2flavonoid glucuronidationGO:05269610.2UGT1A1, UGT1A3
3cellular glucuronidationGO:05269510.1UGT1A1, UGT1A6
4drug catabolic processGO:04273710.1CYP2C9, CYP2D6
5omega-hydroxylase P450 pathwayGO:09726710.0CYP2C9, CYP2C19
6oxidative demethylationGO:07098910.0CYP2C9, CYP2D6
7heterocycle metabolic processGO:0464839.8UGT1A1, CYP2D6, CYP2E1, CYP2C19
8exogenous drug catabolic processGO:0427389.8CYP2C19, CYP2C9
9monoterpenoid metabolic processGO:0160989.8CYP2C9, CYP2D6, CYP2E1, CYP2C19
10oxidation-reduction processGO:0551149.7CYP2C9, CYP2D6, CYP2E1, CYP2C19
11epoxygenase P450 pathwayGO:0193739.6CYP2C19, CYP2C9
12drug metabolic processGO:0171449.5UGT1A1, CYP2C9, CYP2D6, CYP2E1, CYP2C19
13steroid metabolic processGO:0082029.5CYP2C19, CYP2E1, CYP2D6, CYP2C9, UGT1A1
14xenobiotic metabolic processGO:0068058.6GSTT1, UGT1A6, UGT1A1, CYP2C9, CYP2D6, CYP2E1
15small molecule metabolic processGO:0442817.2CYP2D6, CYP2C9, GLUD1, UGT1A1, UGT1A6, CAT

Molecular functions related to Drug-Induced Hepatitis according to GeneCards/GeneDecks:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1arylamine N-acetyltransferase activityGO:00406010.2NAT1, NAT2
2retinoic acid bindingGO:00197210.1UGT1A3, UGT1A1, UGT1A6
3glucuronosyltransferase activityGO:01502010.1UGT1A6, UGT1A1, UGT1A3
4(R)-limonene 6-monooxygenase activityGO:05274110.1CYP2C9, CYP2C19
5(S)-limonene 7-monooxygenase activityGO:01867610.1CYP2C9, CYP2C19
6(S)-limonene 6-monooxygenase activityGO:01867510.0CYP2C9, CYP2C19
7steroid hydroxylase activityGO:0083959.9CYP2C19, CYP2C9
8monooxygenase activityGO:0044979.8CYP2C19, CYP2E1, CYP2D6, CYP2C9
9oxidoreductase activityGO:0164919.8CYP2C9, CYP2D6, CYP2E1, CYP2C19
10heme bindingGO:0200379.4CAT, CYP2C9, CYP2D6, CYP2E1, CYP2C19
11iron ion bindingGO:0055069.4CYP2C9, CYP2D6, CYP2E1, CYP2C19
12electron carrier activityGO:0090559.2CYP2C19, CYP2E1, CYP2D6, CYP2C9
13enzyme bindingGO:0198999.2GSTM1, CAT, UGT1A6, UGT1A1, UGT1A3, CYP2E1
14protein homodimerization activityGO:0428039.0CAT, UGT1A6, UGT1A1, UGT1A3, GHR, GSTM1

Products for genes affiliated with Drug-Induced Hepatitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Drug-Induced Hepatitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet