MCID: DRG004
MIFTS: 26

Drug-Induced Mental Disorder

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Drug-Induced Mental Disorder

MalaCards integrated aliases for Drug-Induced Mental Disorder:

Name: Drug-Induced Mental Disorder 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:1203
ICD9CM 34 292.8 292.89
UMLS 69 C0154325

Summaries for Drug-Induced Mental Disorder

MalaCards based summary : Drug-Induced Mental Disorder is related to schizophrenia 5 and schizoid personality disorder. An important gene associated with Drug-Induced Mental Disorder is HTR1A (5-Hydroxytryptamine Receptor 1A), and among its related pathways/superpathways are Serotonergic synapse and GPCRs, Other. Related phenotypes are shRNA abundance <= 50% and behavior/neurological

Related Diseases for Drug-Induced Mental Disorder

Diseases related to Drug-Induced Mental Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 schizophrenia 5 10.6 HTR1A HTR2A
2 schizoid personality disorder 10.6 HTR1A HTR2A
3 hypoactive sexual desire disorder 10.5 HTR1A HTR2A
4 substance-induced psychosis 10.5 HTR1A HTR2A
5 parkinson disease, mitochondrial 10.4 NDUFS4 PINK1
6 tendinitis 10.3 LHB PHB2
7 bursitis 10.3 NDUFS4 PHB2
8 polysubstance abuse 10.3 CNR1 DRD2
9 tardive dyskinesia 10.3 DRD2 HTR2A
10 anxiety 10.3 CNR1 HTR1A HTR2A
11 alcoholic psychosis 10.3 DRD2 HTR2A
12 periodic limb movement disorder 10.2 DRD2 HTR1A HTR2A
13 rumination disorder 10.2 HTR1A HTR7
14 generalized anxiety disorder 10.2 DRD2 HTR1A HTR2A
15 personality disorder 10.2 DRD2 HTR1A HTR2A
16 interval angle-closure glaucoma 10.2 IDH1 IDH2
17 adult oligodendroglioma 10.2 IDH1 IDH2
18 enchondroma 10.2 IDH1 IDH2
19 intracranial chondrosarcoma 10.2 IDH1 IDH2
20 coronary artery vasospasm 10.2 HTR2A HTR7
21 central nervous system disease 10.2 CNR1 HTR2A PINK1
22 glioma susceptibility 1 10.2 IDH1 IDH2
23 mood disorder 10.2 DRD2 HTR1A HTR2A
24 post-traumatic stress disorder 10.2 CNR1 DRD2 HTR2A
25 anaplastic oligodendroglioma 10.2 IDH1 IDH2
26 early-onset schizophrenia 10.2 DRD2 HTR2A NDUFS4
27 psychotic disorder 10.2 DRD2 HTR1A HTR2A
28 cytogenetically normal acute myeloid leukemia 10.2 IDH1 IDH2
29 chondroblastic osteosarcoma 10.2 IDH1 IDH2
30 obsessive-compulsive disorder 10.2 DRD2 HTR1A HTR2A
31 intraductal papilloma 10.2 IDH1 IDH2
32 multiple enchondromatosis, maffucci type 10.1 IDH1 IDH2
33 psychosexual disorder 10.1 HTR1A HTR2A HTR7
34 spindle cell hemangioma 10.1 IDH1 IDH2
35 mental depression 10.1 HTR1A HTR2A HTR7
36 dysthymic disorder 10.1 HTR2A HTR7
37 bruxism 10.1 DRD2 HTR2A
38 periosteal chondrosarcoma 10.1 IDH1 IDH2
39 adult astrocytic tumour 10.0 IDH1 IDH2
40 kleptomania 10.0 HTR1A HTR7
41 fibrillary astrocytoma 10.0 IDH1 IDH2
42 undifferentiated pleomorphic sarcoma 10.0 IDH1 IDH2
43 pathological gambling 9.9 DRD2 HTR2A
44 periosteal osteogenic sarcoma 9.8 FOS IDH1
45 motion sickness 9.7 FOS HTR1A HTR7
46 withdrawal disorder 9.6 CNR1 FOS HTR7
47 pain agnosia 9.6 CNR1 FOS HTR7
48 agnosia 9.6 CNR1 FOS HTR7
49 attention deficit-hyperactivity disorder 9.6 DRD2 FOS HTR1A HTR2A
50 parkinson disease, late-onset 9.6 CNR1 DRD2 HTR1A HTR2A NDUFS4 PINK1

Graphical network of the top 20 diseases related to Drug-Induced Mental Disorder:



Diseases related to Drug-Induced Mental Disorder

Symptoms & Phenotypes for Drug-Induced Mental Disorder

GenomeRNAi Phenotypes related to Drug-Induced Mental Disorder according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 shRNA abundance <= 50% GR00343-S 9.36 ADAMTS2 DRD2 DUSP26 EPHA5 FOS HTR1A

MGI Mouse Phenotypes related to Drug-Induced Mental Disorder:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.97 HTR2A HTR7 NDUFS4 CNR1 PHB2 PINK1
2 growth/size/body region MP:0005378 9.96 IDH1 ADAMTS2 NDUFS4 CNR1 PHB2 DRD2
3 integument MP:0010771 9.7 HTR7 ADAMTS2 NDUFS4 CNR1 PHB2 DRD2
4 nervous system MP:0003631 9.61 HTR7 NDUFS4 CNR1 PINK1 DRD2 EPHA5
5 skeleton MP:0005390 9.28 IDH1 ADAMTS2 NDUFS4 CNR1 DRD2 PINK1

Drugs & Therapeutics for Drug-Induced Mental Disorder

Search Clinical Trials , NIH Clinical Center for Drug-Induced Mental Disorder

Genetic Tests for Drug-Induced Mental Disorder

Anatomical Context for Drug-Induced Mental Disorder

Publications for Drug-Induced Mental Disorder

Variations for Drug-Induced Mental Disorder

Expression for Drug-Induced Mental Disorder

Search GEO for disease gene expression data for Drug-Induced Mental Disorder.

Pathways for Drug-Induced Mental Disorder

GO Terms for Drug-Induced Mental Disorder

Cellular components related to Drug-Induced Mental Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrion GO:0005739 9.5 CNR1 DUSP26 IDH1 IDH2 NDUFS4 PHB2
2 axon GO:0030424 9.1 CNR1 DRD2 EPHA5 HTR2A PHB2 PINK1

Biological processes related to Drug-Induced Mental Disorder according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 mitochondrion organization GO:0007005 9.63 IDH2 PHB2 PINK1
2 response to light stimulus GO:0009416 9.6 DRD2 FOS
3 regulation of dopamine secretion GO:0014059 9.59 DRD2 HTR2A
4 behavioral response to cocaine GO:0048148 9.58 DRD2 HTR2A
5 temperature homeostasis GO:0001659 9.58 DRD2 HTR2A
6 G-protein coupled serotonin receptor signaling pathway GO:0098664 9.57 HTR1A HTR2A
7 smooth muscle contraction GO:0006939 9.56 HTR2A HTR7
8 2-oxoglutarate metabolic process GO:0006103 9.54 IDH1 IDH2
9 vasoconstriction GO:0042310 9.52 HTR1A HTR7
10 negative regulation of synaptic transmission, glutamatergic GO:0051967 9.51 DRD2 HTR2A
11 regulation of synaptic transmission, GABAergic GO:0032228 9.49 CNR1 DRD2
12 behavior GO:0007610 9.48 HTR1A HTR2A
13 sleep GO:0030431 9.43 FOS HTR2A
14 regulation of behavior GO:0050795 9.4 HTR1A HTR2A
15 regulation of hormone secretion GO:0046883 9.37 HTR1A HTR2A
16 isocitrate metabolic process GO:0006102 9.32 IDH1 IDH2
17 serotonin receptor signaling pathway GO:0007210 9.26 HTR1A HTR2A
18 adenylate cyclase-inhibiting serotonin receptor signaling pathway GO:0007198 9.16 HTR1A HTR7
19 negative regulation of dopamine secretion GO:0033602 8.96 CNR1 DRD2
20 glyoxylate cycle GO:0006097 8.62 IDH1 IDH2
21 G-protein coupled receptor signaling pathway GO:0007186 10.02 CNR1 DRD2 HTR1A HTR2A HTR7 LHB

Molecular functions related to Drug-Induced Mental Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signal transducer activity GO:0004871 9.71 CNR1 DRD2 HTR1A HTR2A
2 drug binding GO:0008144 9.54 CNR1 DRD2 HTR2A
3 neurotransmitter receptor activity GO:0030594 9.33 HTR1A HTR2A HTR7
4 isocitrate dehydrogenase activity GO:0004448 9.32 IDH1 IDH2
5 isocitrate dehydrogenase (NADP+) activity GO:0004450 9.26 IDH1 IDH2
6 G-protein coupled serotonin receptor activity GO:0004993 9.13 HTR1A HTR2A HTR7
7 serotonin binding GO:0051378 8.8 HTR1A HTR2A HTR7

Sources for Drug-Induced Mental Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....