MCID: DRG001
MIFTS: 22

Drug Psychosis malady

Summaries for Drug Psychosis

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Stimulant psychosis is a psychotic disorder that occurs in some people who use stimulant drugs.... more...

MalaCards: Drug Psychosis, also known as drug-induced psychotic disorder, is related to dyspepsia and adenocarcinoma. An important gene associated with Drug Psychosis is LHB (luteinizing hormone beta polypeptide), and among its related pathways are Prostacyclin signalling through prostacyclin receptor and Monoamine GPCRs. The compounds asenapine and doxepin have been mentioned in the context of this disorder.

Aliases & Classifications for Drug Psychosis

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 27ICD9CM, 57SNOMED-CT, 40NCIt, 35MeSH
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Aliases & Descriptions:

drug psychosis 8 10
drug-induced psychotic disorder 8
drug-induced psychosis 8
psychoses, drug 61


External Ids:

Disease Ontology8 DOID:1742
ICD9CM27 292.1
NCIt40 C34957
MeSH35 D011605

Related Diseases for Drug Psychosis

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Drug Psychosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1dyspepsia10.0HRH2
2adenocarcinoma10.0BCHE
3parkinson's disease10.0HTR1A
4pancreatitis10.0BCHE
5ischemia10.0HRH2, HTR1A
6amnestic disorder10.0BCHE, HTR1A
7vascular dementia10.0BCHE, HTR1A
8memory impairment10.0BCHE, HTR1A
9factor v leiden thrombophilia10.0BCHE, HRH2
10alzheimer's disease10.0HTR1A, HRH2, BCHE

Graphical network of diseases related to Drug Psychosis:



Diseases related to drug psychosis

Clinical Features for Drug Psychosis

Drugs & Therapeutics for Drug Psychosis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Drug Psychosis

Drug clinical trials:

Search ClinicalTrials for Drug Psychosis

Search NIH Clinical Center for Drug Psychosis

Search CenterWatch for Drug Psychosis

Genetic Tests for Drug Psychosis

Anatomical Context for Drug Psychosis

Animal Models for Drug Psychosis or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Drug Psychosis

Sources:
51PubMed
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Articles related to Drug Psychosis:

idTitleAuthorsYear
1
The atypical anxiolytic drug, tofisopam, selectively blocks phosphodiesterase isoenzymes and is active in the mouse model of negative symptoms of psychosis. (20967473)
2010
2
A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis. (17526600)
2007
3
Serotonin and dopamine interactions in rodents and primates: implications for psychosis and antipsychotic drug development. (17349861)
2007
4
Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis. (15864111)
2005
5
Psychosis and drug dependence: results from a national survey of prisoners. (12411264)
2002
6
Analysis of overall gene expression induced by amphetamine and phencyclidine: novel targets for the treatment of drug psychosis and schizophrenia. (11812256)
2002
7
Atypical antipsychotics in the treatment of drug-induced psychosis in Parkinson's disease. (10752567)
2000
8
Mianserin treatment of patients with psychosis induced by antiparkinsonian drugs. (7772616)
1995
9
Concentration of cholecystokinin in cerebrospinal fluid is decreased in psychosis: relationship to symptoms and drug response. (1956989)
1991
10
Psychotropic drug interactions in the patient with late-onset psychosis and mood disorder. Part 1. (2898135)
1988

Genetic Variations for Drug Psychosis

Expression for genes affiliated with Drug Psychosis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Drug Psychosis

Search GEO for disease gene expression data for Drug Psychosis.

Pathways for genes affiliated with Drug Psychosis

Sources:
54Reactome, 38NCBI BioSystems Database, 50PharmGKB, 30KEGG, 52QIAGEN
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Compounds for genes affiliated with Drug Psychosis

Sources:
29IUPHAR, 11DrugBank, 45Novoseek, 50PharmGKB, 24HMDB
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Compounds related to Drug Psychosis according to GeneCards/GeneDecks:

(show all 15)
idCompoundScoreTop Affiliating Genes
1asenapine29 1110.6HRH2, HTR1A
2doxepin45 29 50 1112.6HTR1A, HRH2
3nizatidine45 1110.4BCHE, HRH2
4urethane459.4BCHE, HRH2
5ranitidine45 29 11 2412.4BCHE, HRH2
65-hydroxytryptamine459.3HTR1A, HRH2
7scopolamine45 29 11 2412.3BCHE, HTR1A
8atropine45 29 1111.2BCHE, HRH2
9amitriptyline45 50 29 1112.2HTR1A, BCHE
10amine459.2BCHE, HRH2
11chlorpromazine45 29 50 1112.2BCHE, HTR1A
12aspirin45 50 29 2412.1BCHE, HRH2
13guanine45 11 2411.0HRH2, HTR1A
14carbon459.0BCHE, HRH2
15acetylcholine45 50 29 11 2412.7BCHE, HRH2, HTR1A

GO Terms for genes affiliated with Drug Psychosis

Sources:
16Gene Ontology
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Cellular components related to Drug Psychosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1integral to plasma membraneGO:0058878.8HRH2, EPHA5, HTR1A

Products for genes affiliated with Drug Psychosis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Drug Psychosis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet