MCID: DRG001
MIFTS: 27

Drug Psychosis malady

Summaries for Drug Psychosis

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Sources:
63Wikipedia, 32MalaCards
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Wikipedia:63 Stimulant psychosis is a psychotic disorder that occurs in some people who use stimulant drugs.... more...

MalaCards: Drug Psychosis, also known as drug-induced psychotic disorder, is related to parkinson's disease and schizophrenia. An important gene associated with Drug Psychosis is LHB (luteinizing hormone beta polypeptide), and among its related pathways are Prostacyclin signalling through prostacyclin receptor and Monoamine GPCRs. The compounds asenapine and doxepin have been mentioned in the context of this disorder.

Aliases & Classifications for Drug Psychosis

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 27ICD9CM, 56SNOMED-CT, 39NCIt, 34MeSH
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Aliases & Descriptions:

drug psychosis 8 10
drug-induced psychotic disorder 8
drug-induced psychosis 8
psychoses, drug 60


External Ids:

Disease Ontology8 DOID:1742
ICD9CM27 292.1
NCIt39 C34957
MeSH34 D011605

Related Diseases for Drug Psychosis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Drug Psychosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1parkinson's disease30.1HTR1A
2schizophrenia10.0
3dyspepsia10.0HRH2
4adenocarcinoma10.0BCHE
5pancreatitis10.0BCHE
6ischemia10.0HRH2, HTR1A
7amnestic disorder10.0BCHE, HTR1A
8vascular dementia10.0BCHE, HTR1A
9memory impairment10.0BCHE, HTR1A
10factor v leiden thrombophilia10.0BCHE, HRH2
11alzheimer's disease10.0HTR1A, HRH2, BCHE

Graphical network of diseases related to Drug Psychosis:



Diseases related to drug psychosis

Clinical Features for Drug Psychosis

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Drugs & Therapeutics for Drug Psychosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Drug Psychosis

Search CenterWatch for Drug Psychosis

Genetic Tests for Drug Psychosis

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Anatomical Context for Drug Psychosis

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Animal Models for Drug Psychosis or affiliated genes

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Publications for Drug Psychosis

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Sources:
50PubMed
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Articles related to Drug Psychosis:

idTitleAuthorsYear
1
The atypical anxiolytic drug, tofisopam, selectively blocks phosphodiesterase isoenzymes and is active in the mouse model of negative symptoms of psychosis. (20967473)
2010
2
A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis. (17526600)
2007
3
Serotonin and dopamine interactions in rodents and primates: implications for psychosis and antipsychotic drug development. (17349861)
2007
4
Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis. (15864111)
2005
5
Psychosis and drug dependence: results from a national survey of prisoners. (12411264)
2002
6
Analysis of overall gene expression induced by amphetamine and phencyclidine: novel targets for the treatment of drug psychosis and schizophrenia. (11812256)
2002
7
Atypical antipsychotics in the treatment of drug-induced psychosis in Parkinson's disease. (10752567)
2000
8
Mianserin treatment of patients with psychosis induced by antiparkinsonian drugs. (7772616)
1995
9
Concentration of cholecystokinin in cerebrospinal fluid is decreased in psychosis: relationship to symptoms and drug response. (1956989)
1991
10
Psychotropic drug interactions in the patient with late-onset psychosis and mood disorder. Part 1. (2898135)
1988

Genetic Variations for Drug Psychosis

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Expression for genes affiliated with Drug Psychosis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Drug Psychosis

Search GEO for disease gene expression data for Drug Psychosis.

Pathways for genes affiliated with Drug Psychosis

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Sources:
53Reactome, 37NCBI BioSystems Database, 49PharmGKB, 29KEGG, 51QIAGEN
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Compounds for genes affiliated with Drug Psychosis

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Sources:
28IUPHAR, 11DrugBank, 44Novoseek, 49PharmGKB, 24HMDB
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Compounds related to Drug Psychosis according to GeneCards/GeneDecks:

(show all 15)
idCompoundScoreTop Affiliating Genes
1asenapine28 1110.6HRH2, HTR1A
2doxepin44 28 49 1112.6HTR1A, HRH2
3nizatidine44 1110.4BCHE, HRH2
4urethane449.4BCHE, HRH2
5ranitidine44 28 11 2412.4BCHE, HRH2
65-hydroxytryptamine449.3HTR1A, HRH2
7scopolamine44 28 11 2412.3BCHE, HTR1A
8atropine44 28 1111.2BCHE, HRH2
9amitriptyline44 49 28 1112.2HTR1A, BCHE
10amine449.2BCHE, HRH2
11chlorpromazine44 28 49 1112.2BCHE, HTR1A
12aspirin44 49 28 2412.1BCHE, HRH2
13guanine44 11 2411.0HRH2, HTR1A
14carbon449.0BCHE, HRH2
15acetylcholine44 49 28 11 2412.7BCHE, HRH2, HTR1A

GO Terms for genes affiliated with Drug Psychosis

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Sources:
16Gene Ontology
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Cellular components related to Drug Psychosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1integral to plasma membraneGO:0058878.8HRH2, EPHA5, HTR1A

Products for genes affiliated with Drug Psychosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Drug Psychosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet