MCID: DRG012
MIFTS: 19

Drug Rash with Eosinophilia and Systemic Symptoms malady

Skin diseases, Immune diseases categories

Summaries for Drug Rash with Eosinophilia and Systemic Symptoms

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63Wikipedia, 32MalaCards
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Wikipedia:63 DRESS syndrome stands for Drug Reaction (or Rash) with Eosinophilia and Systemic Symptoms. The term was... more...

MalaCards: Drug Rash with Eosinophilia and Systemic Symptoms, also known as drug reaction eosinophilic systemic syndrome, is related to eosinophilia and acute liver failure, and has symptoms including pustula/pustulosis, enanthema/aphtosa/aphta/leukoplakia and hepatitis/icterus/cholestasis. Affiliated tissues include skin, lung and thyroid.

Aliases & Classifications for Drug Rash with Eosinophilia and Systemic Symptoms

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48Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases, Immune diseases


Characteristics (Orphanet epidemiological data):

48
drug rash with eosinophilia and systemic symptoms:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

drug rash with eosinophilia and systemic symptoms 48
drug reaction eosinophilic systemic syndrome 48
dress syndrome 48


Related Diseases for Drug Rash with Eosinophilia and Systemic Symptoms

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17GeneCards, 18GeneDecks
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Diseases related to Drug Rash with Eosinophilia and Systemic Symptoms via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1eosinophilia11.3
2acute liver failure10.4
3stevens-johnson syndrome10.4
4c1 inhibitor deficiency10.4
5interstitial nephritis10.4
6pancreatitis10.4
7tuberculosis10.4
8autoimmune hepatitis10.0
9brucellosis10.0
10endocarditis10.0
11purpura10.0

Graphical network of diseases related to Drug Rash with Eosinophilia and Systemic Symptoms:



Diseases related to drug rash with eosinophilia and systemic symptoms

Clinical Features for Drug Rash with Eosinophilia and Systemic Symptoms

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48Orphanet
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Symptoms:

48 (show all 31)
  • pustula/pustulosis
  • enanthema/aphtosa/aphta/leukoplakia
  • hepatitis/icterus/cholestasis
  • acute hepatic failure
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • cough
  • myocardium anomalies/myocarditis
  • interstitial nephropathy
  • renal failure
  • nephrotic syndrome
  • pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria
  • peripheral neuropathy
  • eosinophils anomalies/hypereosinophilia
  • hyperlymphocytosis
  • interstitial/restrictive pneumopathy/restrictive respiratory syndrome
  • cutaneous rash
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • macules
  • follicular/erythematous/edematous papules/milium
  • negative nikolski's sign
  • collapse/sudden death/cardiac arrest/cardiorespiratory arrest
  • lymphadenopathy/polyadenopathies
  • thyroiditis
  • encephalitis
  • severe allergic reaction/atopy
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • fever/chilling
  • angioedema/angioneurotic edema
  • abnormal hepatic enzymes/transaminases
  • lung/pulmonary infiltrates
  • dry/squaly skin/exfoliation

Drugs & Therapeutics for Drug Rash with Eosinophilia and Systemic Symptoms

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Genetic Tests for Drug Rash with Eosinophilia and Systemic Symptoms

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Anatomical Context for Drug Rash with Eosinophilia and Systemic Symptoms

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32MalaCards
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MalaCards organs/tissues related to Drug Rash with Eosinophilia and Systemic Symptoms:

32
Skin, Lung, Thyroid

Animal Models for Drug Rash with Eosinophilia and Systemic Symptoms or affiliated genes

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Publications for Drug Rash with Eosinophilia and Systemic Symptoms

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Genetic Variations for Drug Rash with Eosinophilia and Systemic Symptoms

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Expression for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

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15Gene Expression Omnibus DataSets
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Search GEO for disease gene expression data for Drug Rash with Eosinophilia and Systemic Symptoms.

Pathways for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

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Compounds for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

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GO Terms for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

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Products for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Drug Rash with Eosinophilia and Systemic Symptoms

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet