MCID: DRG012
MIFTS: 29

Drug Rash with Eosinophilia and Systemic Symptoms malady

Skin diseases, Immune diseases, Rare diseases categories
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Summaries for Drug Rash with Eosinophilia and Systemic Symptoms

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65Wikipedia, 33MalaCards
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Wikipedia:65 DRESS syndrome stands for Drug Reaction (or Rash) with Eosinophilia and Systemic Symptoms. The term was... more...

MalaCards: Drug Rash with Eosinophilia and Systemic Symptoms, also known as drug reaction eosinophilic systemic syndrome, is related to eosinophilia and hepatitis, and has symptoms including thyroiditis, abnormal hepatic enzymes/transaminases and lymphadenopathy/polyadenopathies. Affiliated tissues include skin, lung and thyroid.

Aliases & Classifications for Drug Rash with Eosinophilia and Systemic Symptoms

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49Orphanet, 63UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Skin diseases, Immune diseases


Characteristics (Orphanet epidemiological data):

49
drug rash with eosinophilia and systemic symptoms:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

drug rash with eosinophilia and systemic symptoms 49
drug reaction eosinophilic systemic syndrome 49
dress syndrome 49


External Ids:

UMLS via Orphanet63 C1142139

Related Diseases for Drug Rash with Eosinophilia and Systemic Symptoms

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17GeneCards, 18GeneDecks
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Diseases related to Drug Rash with Eosinophilia and Systemic Symptoms via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 21)
idRelated DiseaseScoreTop Affiliating Genes
1eosinophilia11.3
2hepatitis10.6
3acute liver failure10.4
4graft versus host disease10.4
5hepatitis a10.4
6stevens-johnson syndrome10.4
7interstitial nephritis10.4
8pancreatitis10.4
9tuberculosis10.4
10toxic epidermal necrolysis10.4
11septic shock10.4
12nephritis10.4
13acute generalized exanthematous pustulosis10.4
14dysphagia10.1
15autoimmune hepatitis10.0
16cerebritis10.0
17brucellosis10.0
18endocarditis10.0
19purpura10.0
20vasculitis10.0
21chylous ascites10.0

Graphical network of the top 20 diseases related to Drug Rash with Eosinophilia and Systemic Symptoms:



Diseases related to drug rash with eosinophilia and systemic symptoms

Symptoms for Drug Rash with Eosinophilia and Systemic Symptoms

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49Orphanet
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Symptoms:

49 (show all 31)
  • thyroiditis
  • abnormal hepatic enzymes/transaminases
  • lymphadenopathy/polyadenopathies
  • enanthema/aphtosa/aphta/leukoplakia
  • eosinophils anomalies/hypereosinophilia
  • severe allergic reaction/atopy
  • pustula/pustulosis
  • angioedema/angioneurotic edema
  • negative nikolski's sign
  • acute hepatic failure
  • hyperlymphocytosis
  • nephrotic syndrome
  • interstitial nephropathy
  • myocardium anomalies/myocarditis
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • collapse/sudden death/cardiac arrest/cardiorespiratory arrest
  • encephalitis
  • renal failure
  • fever/chilling
  • hepatitis/icterus/cholestasis
  • dry/squaly skin/exfoliation
  • cutaneous rash
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • macules
  • follicular/erythematous/edematous papules/milium
  • peripheral neuropathy
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • cough
  • interstitial/restrictive pneumopathy/restrictive respiratory syndrome
  • lung/pulmonary infiltrates
  • pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria

Drugs & Therapeutics for Drug Rash with Eosinophilia and Systemic Symptoms

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Genetic Tests for Drug Rash with Eosinophilia and Systemic Symptoms

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Anatomical Context for Drug Rash with Eosinophilia and Systemic Symptoms

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33MalaCards
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MalaCards organs/tissues related to Drug Rash with Eosinophilia and Systemic Symptoms:

33
Skin, Lung, Thyroid, Liver, Testes, Thymus

Animal Models for Drug Rash with Eosinophilia and Systemic Symptoms or affiliated genes

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Publications for Drug Rash with Eosinophilia and Systemic Symptoms

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52PubMed
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Articles related to Drug Rash with Eosinophilia and Systemic Symptoms:

(show top 50)    (show all 59)
idTitleAuthorsYear
1
Liver transplantation in a child with acute liver failure resulting from drug rash with eosinophilia and systemic symptoms syndrome. (23741237)
2013
2
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome and hepatitis induced by phenytoin. (23829691)
2013
3
Pentoxifylline-induced drug rash with eosinophilia and systemic symptoms (DRESS) in a patient with caffeine intolerance. (24133560)
2013
4
Case report of drug rash with eosinophilia and systemic symptoms demonstrating human herpesvirus-6 reactivation. (24016284)
2013
5
Identification of thymus and activation-regulated chemokine (TARC/CCL17) as a potential marker for early indication of disease and prediction of disease activity in drug-induced hypersensitivity syndrome (DIHS)/drug rash with eosinophilia and systemic symptoms (DRESS). (23141052)
2013
6
Drug rash with eosinophilia and systemic symptoms syndrome associated with use of phenytoin, divalproex sodium, and phenobarbital. (23456403)
2013
7
Drug rash with eosinophilia and systemic symptoms (DRESS) in patients receiving strontium ranelate. (23361875)
2013
8
Drug rash with eosinophilia and systemic symptoms (DRESS syndrome). (22611746)
2012
9
Drug rash with eosinophilia and systemic symptoms (DRESS) probably induced by cefotaxime: a report of two cases. (21817121)
2012
10
A case of drug rash with eosinophilia and systemic symptoms (DRESS) syndrome complicating airway management. (22271506)
2012
11
Drug rash with eosinophilia and systemic symptoms syndrome following cholestatic hepatitis A: a case report. (22511907)
2012
12
Allopurinol-induced drug rash with eosinophilia and systemic symptoms mimicking acute generalized exanthematous pustulosis. (22901319)
2012
13
The importance of vancomycin in drug rash with eosinophilia and systemic symptoms (DRESS) syndrome. (22525393)
2012
14
Allopurinol causing drug rash with eosinophilia and systemic symptoms syndrome: a challenging diagnosis. (22162933)
2011
15
Case of drug rash with eosinophilia and systemic symptoms induced by zonisamide and reactivation of human herpes virus 7. (21998830)
2011
16
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by cidofovir. (20846239)
2011
17
Ceftobiprole associated agranulocytosis after drug rash with eosinophilia and systemic symptoms induced by vancomycin and rifampicin. (21219413)
2011
18
Photodistribution of rash in phenytoin-induced drug rash with eosinophilia and systemic symptoms. (21418282)
2011
19
Drug rash with eosinophilia and systemic symptoms: two emergency department cases. (22224160)
2011
20
First report of lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome with pancreatitis. (21098750)
2010
21
Comparison of the causes and clinical features of drug rash with eosinophilia and systemic symptoms and stevens-johnson syndrome. (20358026)
2010
22
Drug rash with eosinophilia and systemic symptoms secondary to sulfasalazine. (20546480)
2010
23
Drug rash with eosinophilia and systemic symptoms due to telaprevir. (20798484)
2010
24
Drug rash with eosinophilia and systemic symptoms (DRESS): changing carbamazepine to phenobarbital controlled epilepsy without the recurrence of DRESS. (20103499)
2010
25
Drug rash with eosinophilia and systemic symptoms syndrome associated with clindamycin. (20843501)
2010
26
Drug rash with eosinophilia and systemic symptoms syndrome induced by sulfasalazine. (19854669)
2010
27
Hypersensitivity to amoxicillin after drug rash with eosinophilia and systemic symptoms (DRESS) to carbamazepine and allopurinol: a possible co-sensitization. (20653681)
2010
28
Antituberculosis drug-induced drug rash with eosinophilia and systemic symptoms syndrome confirmed by patch testing. (21314014)
2010
29
Linezolid-associated acute interstitial nephritis and drug rash with eosinophilia and systemic symptoms (DRESS) syndrome. (19733945)
2009
30
Drug rash with eosinophilia and systemic symptoms after chlorambucil treatment in chronic lymphocytic leukaemia. (19122478)
2009
31
Severe vancomycin-induced drug rash with eosinophilia and systemic symptoms syndrome imitating septic shock. (19424074)
2009
32
Drug rash with eosinophilia and systemic symptoms after penicillin V administration in a patient with acquired C1 inhibitor acquired deficiency. (19639734)
2009
33
Drug rash with eosinophilia and systemic symptoms and graft-versus-host disease developing sequentially in a patient. (18793307)
2009
34
The variable clinical picture of drug-induced hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms in relation to the eliciting drug. (19563993)
2009
35
Drug rash with eosinophilia and systemic symptoms induced by cefotaxime and ampicillin. (18533962)
2008
36
Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome induced by celecoxib and anti-tuberculosis drugs. (18583892)
2008
37
Clinicopathological features and prognosis of drug rash with eosinophilia and systemic symptoms: a study of 30 cases in Taiwan. (18627428)
2008
38
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome: suspected association with titanium bioprosthesis. (17873538)
2007
39
Drug rash with eosinophilia and systemic symptoms after ibuprofen intake. (17982931)
2007
40
Drug rash with eosinophilia and systemic symptoms syndrome due to quinine. (18097122)
2007
41
Association of hypogammaglobulinemia with DRESS (Drug Rash with Eosinophilia and Systemic Symptoms). (17229608)
2006
42
Possible drug rash with eosinophilia and systemic symptoms syndrome after exposure to epoetin alfa. (16303911)
2005
43
Drug rash with eosinophilia and systemic symptoms vs toxic epidermal necrolysis: the dilemma of classification. (15896547)
2005
44
Drug rash with eosinophilia and systemic symptoms syndrome and renal toxicity with a nevirapine-containing regimen in a pregnant patient with human immunodeficiency virus. (12738113)
2003
45
Drug rash with eosinophilia and systemic symptoms secondary to phenobarbitone. (12897635)
2003
46
Active human herpesvirus 6 infection in a patient with drug rash with eosinophilia and systemic symptoms. (12839588)
2003
47
Management of drug rash with eosinophilia and systemic symptoms (DRESS syndrome): an update. (12771485)
2003
48
Drug rash with eosinophilia and systemic symptoms caused by topical application of mercury. (11146363)
2000
49
Drug rash with eosinophilia and systemic symptoms (DRESS syndrome). (10544509)
1999
50
DRESS (drug rash with eosinophilia and systemic symptoms) syndrome associated with nevirapine therapy. (9827291)
1998

Variations for Drug Rash with Eosinophilia and Systemic Symptoms

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Expression for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

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15Gene Expression Omnibus DataSets
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Pathways for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

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Compounds for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

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GO Terms for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

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Products for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

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  • Antibodies
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Sources for Drug Rash with Eosinophilia and Systemic Symptoms

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
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44NINDS
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47OMIM
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52PubMed
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59SNOMED-CT via Orphanet
62UMLS
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