MCID: DRG012
MIFTS: 13

Drug Rash with Eosinophilia and Systemic Symptoms malady

Skin, Immune categories

Summaries for Drug Rash with Eosinophilia and Systemic Symptoms

Sources:
64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:64 DRESS syndrome stands for Drug Reaction (or Rash) with Eosinophilia and Systemic Symptoms. The term was... more...

MalaCards: Drug Rash with Eosinophilia and Systemic Symptoms, also known as drug reaction eosinophilic systemic syndrome, is related to acute liver failure and stevens-johnson syndrome, and has symptoms including pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria, respiratory distress/dyspnea/respiratory failure/lung volume reduction and collapse/sudden death/cardiac arrest/cardiorespiratory arrest.

Aliases & Classifications for Drug Rash with Eosinophilia and Systemic Symptoms

Sources:
49Orphanet
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin, Immune


Characteristics (Orphanet epidemiological data):

49
drug rash with eosinophilia and systemic symptoms:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

drug rash with eosinophilia and systemic symptoms 49
drug reaction eosinophilic systemic syndrome 49
dress syndrome 49


Related Diseases for Drug Rash with Eosinophilia and Systemic Symptoms

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Drug Rash with Eosinophilia and Systemic Symptoms via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1acute liver failure10.4
2stevens-johnson syndrome10.4
3drug-induced hepatitis10.4
4tuberculosis10.4
5toxic epidermal necrolysis10.4
6septic shock10.4
7nephritis10.4
8acute generalized exanthematous pustulosis10.4
9autoimmune hepatitis10.0
10chylous ascites10.0

Graphical network of diseases related to Drug Rash with Eosinophilia and Systemic Symptoms:



Diseases related to drug rash with eosinophilia and systemic symptoms

Clinical Features for Drug Rash with Eosinophilia and Systemic Symptoms

Sources:
49Orphanet
See all sources


Symptoms:

49 (show all 31)
  • pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • collapse/sudden death/cardiac arrest/cardiorespiratory arrest
  • encephalitis
  • renal failure
  • fever/chilling
  • hepatitis/icterus/cholestasis
  • dry/squaly skin/exfoliation
  • cutaneous rash
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • macules
  • follicular/erythematous/edematous papules/milium
  • peripheral neuropathy
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • cough
  • interstitial/restrictive pneumopathy/restrictive respiratory syndrome
  • lung/pulmonary infiltrates
  • myocardium anomalies/myocarditis
  • interstitial nephropathy
  • nephrotic syndrome
  • thyroiditis
  • abnormal hepatic enzymes/transaminases
  • lymphadenopathy/polyadenopathies
  • enanthema/aphtosa/aphta/leukoplakia
  • eosinophils anomalies/hypereosinophilia
  • severe allergic reaction/atopy
  • pustula/pustulosis
  • angioedema/angioneurotic edema
  • negative nikolski's sign
  • acute hepatic failure
  • hyperlymphocytosis

Drugs & Therapeutics for Drug Rash with Eosinophilia and Systemic Symptoms

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Drug Rash with Eosinophilia and Systemic Symptoms

Drug clinical trials:

Search ClinicalTrials for Drug Rash with Eosinophilia and Systemic Symptoms

Search NIH Clinical Center for Drug Rash with Eosinophilia and Systemic Symptoms

Search CenterWatch for Drug Rash with Eosinophilia and Systemic Symptoms

Genetic Tests for Drug Rash with Eosinophilia and Systemic Symptoms

Anatomical Context for Drug Rash with Eosinophilia and Systemic Symptoms

Animal Models for Drug Rash with Eosinophilia and Systemic Symptoms or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Drug Rash with Eosinophilia and Systemic Symptoms

Genetic Variations for Drug Rash with Eosinophilia and Systemic Symptoms

Expression for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

Sources:
15Gene Expression Omnibus DataSets
See all sources

Search GEO for disease gene expression data for Drug Rash with Eosinophilia and Systemic Symptoms.

Pathways for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

Compounds for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

GO Terms for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

Products for genes affiliated with Drug Rash with Eosinophilia and Systemic Symptoms

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Drug Rash with Eosinophilia and Systemic Symptoms

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet