MCID: DDN009
MIFTS: 32

Duodenal Obstruction malady

Categories: Gastrointestinal diseases

Aliases & Classifications for Duodenal Obstruction

Aliases & Descriptions for Duodenal Obstruction:

Name: Duodenal Obstruction 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3558
ICD10 33 K31.5
MeSH 42 D004380
NCIt 47 C79548
SNOMED-CT 64 95532008
UMLS 69 C0013292

Summaries for Duodenal Obstruction

MalaCards based summary : Duodenal Obstruction is related to ladd syndrome and duodenitis. An important gene associated with Duodenal Obstruction is PRSS1 (Protease, Serine 1). The drugs Efavirenz and Maraviroc have been mentioned in the context of this disorder. Affiliated tissues include pancreas, colon and breast, and related phenotype is digestive/alimentary.

Related Diseases for Duodenal Obstruction

Diseases related to Duodenal Obstruction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 102)
id Related Disease Score Top Affiliating Genes
1 ladd syndrome 11.0
2 duodenitis 10.9
3 pancreatitis 10.3
4 aneurysm 10.2
5 tricuspid valve insufficiency 10.2 FAM120A PRSS1
6 aortic aneurysm 10.2
7 abdominal aortic aneurysm 10.1
8 primary oculocerebral lymphoma 10.1 CDON NODAL
9 late-onset nephronophthisis 10.1 CDON NODAL
10 antenatal bartter syndrome 10.0 CDON NODAL
11 familial infantile bilateral striatal necrosis 10.0 CDON NODAL
12 atypical hemolytic-uremic syndrome with h factor anomaly 10.0 CDON NODAL
13 primary congenital glaucoma 10.0 PRSS1 SPINK1
14 glaucoma 1, open angle, f 10.0 CDON NODAL
15 myxofibrosarcoma 10.0 PRSS1 SPINK1
16 diastrophic dysplasia 10.0 PRSS1 SPINK1
17 situs inversus 10.0
18 cervical adenomyoma 10.0 PRSS1 SPINK1
19 hypoplastic left heart syndrome 9.9 CDON NODAL
20 pancreatic cancer 9.9
21 chondroma 9.9 PRSS1 SPINK1
22 thyroid gland disease 9.9 PRSS1 SPINK1
23 acute pancreatitis 9.8
24 gastroenteritis 9.8
25 superior mesenteric artery syndrome 9.8
26 eosinophilic gastroenteritis 9.8
27 peritonitis 9.8
28 retroperitoneal fibrosis 9.8
29 netherton syndrome 9.8 PRSS1 SPINK1
30 breast cancer 9.7
31 down syndrome 9.7
32 appendicitis 9.7
33 choledochal cyst 9.7
34 cerebral palsy 9.6
35 hepatitis 9.6
36 lymphoma 9.6
37 ileocolitis 9.6
38 blind loop syndrome 9.6
39 strongyloidiasis 9.6
40 sarcoma 9.6
41 obstructive jaundice 9.6
42 duodenal ulcer 9.6
43 adenocarcinoma 9.6
44 cerebritis 9.6
45 adenoma 9.6
46 intussusception 9.6
47 gastroduodenitis 9.6
48 fibromatosis 9.6
49 isolated levocardia 9.6
50 levocardia 9.6

Graphical network of the top 20 diseases related to Duodenal Obstruction:



Diseases related to Duodenal Obstruction

Symptoms & Phenotypes for Duodenal Obstruction

MGI Mouse Phenotypes related to Duodenal Obstruction:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 8.92 CDON NODAL SPINK1 WAS

Drugs & Therapeutics for Duodenal Obstruction

Drugs for Duodenal Obstruction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 112)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Efavirenz Approved, Investigational Phase 4 154598-52-4 64139
2
Maraviroc Approved, Investigational Phase 4 376348-65-1 3002977
3 Anti-HIV Agents Phase 4
4 Anti-Infective Agents Phase 4,Phase 3
5 Anti-Retroviral Agents Phase 4
6 Antiviral Agents Phase 4
7 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Phase 3
8 Cytochrome P-450 CYP3A Inducers Phase 4
9 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
10 HIV Integrase Inhibitors Phase 4
11 Integrase Inhibitors Phase 4
12 Nucleic Acid Synthesis Inhibitors Phase 4
13 Raltegravir Potassium Phase 4
14 Reverse Transcriptase Inhibitors Phase 4
15 Cola Nutraceutical Phase 4,Phase 1,Phase 2
16
Aspirin Approved, Vet_approved Phase 3 50-78-2 2244
17
Lansoprazole Approved, Investigational Phase 3 103577-45-3 3883
18
Meperidine Approved Phase 3 57-42-1 4058
19
Midazolam Approved, Illicit Phase 3 59467-70-8 4192
20
Famotidine Approved Phase 3 76824-35-6 3325
21
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774
22
Ibuprofen Approved Phase 3 15687-27-1 3672
23
Amoxicillin Approved, Vet_approved Phase 3 26787-78-0 33613 2171
24
Cefuroxime Approved Phase 3 55268-75-2 5361202 5479529
25
Fluconazole Approved Phase 3 86386-73-4 3365
26
Metronidazole Approved Phase 3 443-48-1 4173
27
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
28
Celecoxib Approved, Investigational Phase 3 169590-42-5 2662
29
Naproxen Approved, Vet_approved Phase 3 22204-53-1 1302 156391
30
Menthol Approved Phase 2, Phase 3 2216-51-5 16666
31
Omeprazole Approved, Investigational, Vet_approved Phase 3 73590-58-6 4594
32
Ticlopidine Approved Phase 3 55142-85-3 5472
33
Clopidogrel Approved, Nutraceutical Phase 3 120202-66-6, 113665-84-2 60606
34 Analgesics Phase 3
35 Analgesics, Non-Narcotic Phase 3
36 Antacids Phase 3
37 Anti-Inflammatory Agents Phase 3
38 Anti-Inflammatory Agents, Non-Steroidal Phase 3
39 Antirheumatic Agents Phase 3
40 Anti-Ulcer Agents Phase 3
41 Cyclooxygenase Inhibitors Phase 3
42 Gastrointestinal Agents Phase 3
43 Neurotransmitter Agents Phase 3
44 Peripheral Nervous System Agents Phase 3
45 Antipyretics Phase 3
46
Dexlansoprazole Phase 3 138530-94-6, 103577-45-3 9578005
47 Fibrinolytic Agents Phase 3
48 Platelet Aggregation Inhibitors Phase 3
49
Proton pump inhibitors Phase 3
50 Purinergic P2 Receptor Antagonists Phase 3

Interventional clinical trials:

(show all 45)
id Name Status NCT ID Phase
1 A Pilot Project of Virologic, Pharmacologic and Immunologic Correlates of Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution Following Maraviroc Therapy Completed NCT00870363 Phase 4
2 Impact of Visceral Osteopathic Treatment on Meconium Evacuation in Preterm Infants Completed NCT02140710 Phase 4
3 Endoscopic Stenting Versus Surgical Bypass for Low Bile Duct Obstruction by Cancer of the Pancreatic Head Unknown status NCT00753441 Phase 2, Phase 3
4 Covered Versus Uncovered Self-expandable Metallic Stents for Malignant Gastric Outlet Obstruction Completed NCT01646476 Phase 3
5 Effects of Delayed Enteral Nutrition on Inflammatory Responses and Immune Function Competence in Critically Ill Patients With Prolonged Fasting Completed NCT01834430 Phase 3
6 Clinical Outcomes of EUS-guided Biliary Drainage Using Partially or Fully Covered Metallic Stents Completed NCT02114320 Phase 3
7 Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment Completed NCT00450216 Phase 3
8 Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures Completed NCT01524081 Phase 3
9 A Comparison of Safety and Treatment in Subjects With Osteoarthritis Taking Low Dose Aspirin Completed NCT00175032 Phase 3
10 Study of Gastroduodenal Metallic Stent vs Gastrojejunostomy Recruiting NCT02784470 Phase 3
11 EUS - Guided Choledocho-duodenostomy Versus ERCP With Covered Metallic Stents in Patients With Unresectable Malignant Distal Common Bile Duct Strictures Recruiting NCT03000855 Phase 2, Phase 3
12 Gastric Partitioning Procedure for the Treatment of Unresectable and Obstructive Distal Gastric Cancer Recruiting NCT02064803 Phase 3
13 A Randomized Controlled Trial on EGBD vs PC for Acute Cholecystitis. Recruiting NCT02212717 Phase 2, Phase 3
14 Clopidogrel and the Optimization of Gastrointestinal Events (COGENT-1) Terminated NCT00557921 Phase 3
15 Magnetic Resonance Cholangiopancreatography Versus Endoscopic Retrograde Cholangiopancreatography in the Approach to Patients With Suspected Biliary Obstruction Terminated NCT01424657 Phase 3
16 Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction Completed NCT00004910 Phase 1, Phase 2
17 A Phase II Trial of Ipilimumab and Nivolumab for the Treatment of Rare Cancers Not yet recruiting NCT02923934 Phase 2
18 Evaluation of the Safety and Effectiveness of Tailored Transoral Incisionless Fundoplication (TIF) Using EsophyX for the Treatment of GERD Withdrawn NCT01025739 Phase 2
19 Comparing Endoscopic Based Stent Strategy Versus Bypass Surgery in Non-resectable Periampullary Cancer Withdrawn NCT00487851 Phase 2
20 Magnetic Anastomosis Device Relief of Malignant Gastric Outlet Obstruction Terminated NCT00487552 Phase 1
21 IS There a Correlation Between Sypmtoms of Gastroparesis and the Duration of Video Caspule Retention in the Stomach Unknown status NCT01858220
22 Peptic Ulcer Disease in Ischemic Heart Patients Taking Aspirin and Clopidogrel With or Without Proton Pump Inhibitor Unknown status NCT00854776
23 EVOLUTION® Duodenal Stent for Duodenal or Gastric Outlet Obstruction Caused by Malignant Neoplasms Completed NCT00991614
24 EUS-guided Biliary Drainage Versus Percutanenous Transhepatic Biliary Darinage for Malignant Biliary Obstruction After Failed ERCP Completed NCT02103413
25 Surgical Outcome and Differences on Histopathology in Patients With Alcoholic & Non Alcoholic Chronic Pancreatitis Completed NCT02048267
26 Esophageal High Resolution Manometry and Dysphagia Completed NCT01284894
27 Endoscopic Ultrasound Versus Endoscopic Retrograde Cholangiopancreatography (ERCP) Tissue Sampling for the Diagnosis of Suspected Pancreatico-Biliary Cancer Completed NCT01356030
28 SEGATROM: Sensory and Gastrointestinal Impact of Taste Receptor Variants on Human Metabolism and Nutrition Completed NCT02219295
29 Chronic Marginal Ulcers After Gastric Bypass Completed NCT01041079
30 Systematic Screening for Risk-factors for Ulcer Bleeding Before Anti-thrombotic Treatment Completed NCT01447498
31 Comparison of Duodenal Stenting vs Transpyloric and Duodenal Stenting for Malignant Obstruction Recruiting NCT03125148
32 Endoscopic Gastroenteric Anastomosis With New Tissue Apposing Stent in the Management of Antro-pyloroduodenal Obstruction : Evaluation of Feasibility, Efficacy and Tolerance. Recruiting NCT02562157
33 Efficacy of Partial Covered Double Bare Metal Stent Compared to Uncovered Double Bare Metal Stent in Malignant Biliary Obstruction Recruiting NCT02937246
34 Effect of Papillary Epinephrine Spraying on Post-ERCP Pancreatitis in Patients Received Rectal Indomethacin Recruiting NCT03057769
35 Clinical Outcomes of the Endoscopic Resection of Premalignant and Malignant Gastrointestinal Lesions Recruiting NCT01750619
36 EUS BD vs ERCP TP for Pancreatic Cancer Recruiting NCT03063554
37 Magnamosis First-in-human Study of Feasibility and Safety Recruiting NCT02043392
38 EUS-Guided Rendezvous or Direct Interventions Versus Advanced ERCP Techniques for Biliary Access and Therapy Recruiting NCT01678326
39 Effect of More Distal Enteral Bypass After Pancreaticoduodenectomy: A Prospective Multicenter Randomized Clinical Trial Recruiting NCT01755273
40 Domestic Surgical Robot Clinical Study Recruiting NCT02752698
41 Biliary Drainage in Patients With Duodenal Metal Stent Active, not recruiting NCT02376907
42 Intraoperative Coeliac Plexus Alcohol Neurolysis Along With Frey's Procedure for a Better Pain Relief Active, not recruiting NCT02735330
43 The Effect of Satiety Gut Hormone Modulation on Appetitive Drive After Upper Gastrointestinal Surgery Enrolling by invitation NCT02381249
44 Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer Terminated NCT00899132
45 Safety of Rabeprazole in Patients Under Multiple Treatments Terminated NCT00511745

Search NIH Clinical Center for Duodenal Obstruction

Cochrane evidence based reviews: duodenal obstruction

Genetic Tests for Duodenal Obstruction

Anatomical Context for Duodenal Obstruction

MalaCards organs/tissues related to Duodenal Obstruction:

39
Pancreas, Colon, Breast, Kidney, Lung, T Cells, Liver

Publications for Duodenal Obstruction

Articles related to Duodenal Obstruction:

(show top 50) (show all 539)
id Title Authors Year
1
Temporary duodenal stenting as a bridge to ERCP for inaccessible papilla due to duodenal obstruction: a retrospective study. ( 27652301 )
2016
2
Preduodenal Portal Vein Associated with Duodenal Obstruction of other Etiology: A Case Series. ( 27896162 )
2016
3
Congenital Duodenal Obstruction in Neonates: Over 13 Years' Experience from a Single Centre. ( 27896158 )
2016
4
Endoscopic choledochoduodenostomy and gastrojejunostomy in the treatment of biliary and duodenal obstruction. ( 26684602 )
2016
5
Laparoscopic repair of congenital duodenal obstruction is feasible even in small-volume centres. ( 27652789 )
2016
6
Single-session double-stent placement in concomitant malignant biliary and duodenal obstruction with a cautery-tipped lumen apposing metal stent. ( 27706541 )
2016
7
Duodenal Obstruction on 99mTc-DISIDA Cholescintigraphy: A Noninvasive Approach to Bowel Obstruction Diagnosis. ( 27834726 )
2016
8
Intestinal malrotation associated with duodenal obstruction secondary to Ladd's bands. ( 27777485 )
2016
9
The role of palliative surgery in the management of advanced pancreatic cancer in patients with biliary and duodenal obstruction. ( 26868166 )
2016
10
Randomized controlled exploratory study comparing the usefulness of two types of metallic stents with different axial forces for the management of duodenal obstruction caused by pancreatobiliary cancer. ( 26946214 )
2016
11
Duodenal Obstruction Caused by an Annular Pancreas - Sonographic Diagnosis in a 4-Month-Old Dystrophic Infant. ( 27529456 )
2016
12
Congenital duodenal obstruction with delayed presentation: seven years of experience. ( 27695493 )
2016
13
Preduodenal Portal Vein with Situs Inversus Totalis causing Duodenal Obstruction. ( 27398325 )
2016
14
Congenital duodenal obstruction: causes and imaging approach. ( 27324508 )
2016
15
Duodenal obstruction due to annular pancreas associated with carcinoma of the duodenum. ( 27350844 )
2016
16
Two Cases of Intraluminal "Windsock" Diverticula Resulting in Partial Duodenal Obstruction. ( 27807587 )
2016
17
Palliation double stenting for malignant biliary and duodenal obstruction. ( 26889267 )
2016
18
Neonatal Duodenal Obstruction: A 15-Year Experience. ( 27123397 )
2016
19
Is laparoscopic surgery better than open surgery for the repair of congenital duodenal obstruction? A review of the current evidences. ( 27622585 )
2016
20
Association Between Prenatal Sonographic Findings of Duodenal Obstruction and Adverse Outcomes. ( 27466262 )
2016
21
Self-expandable metal stent placement for malignant duodenal obstruction distal to the bulb. ( 26426837 )
2015
22
Single-session EUS-guided FNA and biliary drainage with use of a biflanged lumen apposing stent on an electrocautery enhanced delivery system: one-stop shop for unresectable pancreatic mass with duodenal obstruction. ( 25922247 )
2015
23
Lumen-apposing metal stent placement for biliary drainage may be preferable in the setting of duodenal obstruction when dual stenting is performed. ( 25887726 )
2015
24
Upper ureteric transitional cell carcinoma, extending to the renal pelvis, presenting as duodenal obstruction. ( 26564110 )
2015
25
Comparison between uncovered and covered self-expandable metal stent placement in malignant duodenal obstruction. ( 25663777 )
2015
26
Bouveret's syndrome: An unusual cause of duodenal obstruction. ( 26239168 )
2015
27
Duodenal Obstruction as First Presentation of Metastatic Breast Cancer. ( 26266075 )
2015
28
Successful endovascular treatment of duodenal obstruction caused by large abdominal aortic aneurysm. ( 26146235 )
2015
29
An unusual cause of duodenal obstruction in adults. ( 25910574 )
2015
30
Laparoscopic simple oblique duodenoduodenostomy in management of congenital duodenal obstruction in children. ( 25536359 )
2015
31
The importance of antenatal diagnosis of congenital duodenal obstruction. ( 26216363 )
2015
32
Duodenal Obstruction Caused by Acute Appendicitis with Intestinal Malrotation in a Child. ( 26317163 )
2015
33
Video of the Month: EUS-Guided Choledochoduodenstomy With a Cautery-Equipped Lumen-Apposing Stent Allows Future Biliary Access in Patients With Type 2 Duodenal Obstruction. ( 26052765 )
2015
34
EUS-guided choledochoduodenostomy with a lumen-apposing metal stent before duodenal stent placement for malignant biliary and duodenal obstruction. ( 25450606 )
2015
35
CT of gastro-duodenal obstruction. ( 26280126 )
2015
36
Comparison of the clinical impact of endoscopic ultrasound-guided choledochoduodenostomy and hepaticogastrostomy for bile duct obstruction with duodenal obstruction. ( 26418074 )
2015
37
Comparison of the clinical impact of endoscopic ultrasound-guided choledochoduodenostomy and hepaticogastrostomy for bile duct obstruction with duodenal obstruction. ( 26382307 )
2015
38
A Case of Duodenal Obstruction and Pancreatitis Due to Intragastric Balloon. ( 26185725 )
2015
39
Duodenal obstruction from a secondary aortoduodenal fistula. ( 24975196 )
2014
40
Laparoscopic diagnosis and treatment of neonates with duodenal obstruction associated with an annular pancreas: report of 11 cases. ( 24477526 )
2014
41
Is routine preoperative screening echocardiogram indicated in all children with congenital duodenal obstruction? ( 24682563 )
2014
42
Duodenal obstruction due to a preduodenal portal vein. ( 25323190 )
2014
43
Malignant pyloro-duodenal obstruction: role of self expandable metallic stents. ( 24605706 )
2014
44
Images in clinical medicine. Congenital duodenal obstruction and double-bubble sign. ( 25207787 )
2014
45
Duodenal stent placement for duodenal obstruction caused by pancreatic cancer associated with annular pancreas. ( 24890427 )
2014
46
Pancreatic kaposiform hemangioendothelioma presenting with duodenal obstruction and kasabach-merritt phenomenon: a neonate cured by whipple operation. ( 25755958 )
2014
47
Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Duodenal Obstruction Without a Discrete Mass. ( 25431045 )
2014
48
Laparoscopic Management of Duodenal Obstruction Resulting From Superior Mesenteric Artery Syndrome. ( 25353279 )
2014
49
Letter to the editor: Duodenal obstruction as the first symptom of the unrecognized breast carcinoma. ( 24913252 )
2014
50
Congenital duodenal obstruction in neonates: a decade's experience from one center. ( 25124975 )
2014

Variations for Duodenal Obstruction

Expression for Duodenal Obstruction

Search GEO for disease gene expression data for Duodenal Obstruction.

Pathways for Duodenal Obstruction

GO Terms for Duodenal Obstruction

Biological processes related to Duodenal Obstruction according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 anterior/posterior pattern specification GO:0009952 8.62 CDON NODAL

Sources for Duodenal Obstruction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....