MCID: DDN001
MIFTS: 48

Duodenal Ulcer

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Duodenal Ulcer

MalaCards integrated aliases for Duodenal Ulcer:

Name: Duodenal Ulcer 12 52 42 14 69
Stress Ulcer 12 52 69
Curling Ulcer 12 69
Stress Ulcer of Stomach 69
Duodenal Ulcer Disease 52
Curling's Ulcers 12

Classifications:



Summaries for Duodenal Ulcer

MalaCards based summary : Duodenal Ulcer, also known as stress ulcer, is related to eosinophilic gastroenteritis and atherosclerosis. An important gene associated with Duodenal Ulcer is HRH2 (Histamine Receptor H2), and among its related pathways/superpathways are Allograft rejection and IL-17 Family Signaling Pathways. The drugs Amoxicillin and Clarithromycin have been mentioned in the context of this disorder. Affiliated tissues include testes, liver and colon.

Related Diseases for Duodenal Ulcer

Diseases in the Duodenal Ulcer family:

Duodenal Ulcer Due to Antral G-Cell Hyperfunction

Diseases related to Duodenal Ulcer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 300)
id Related Disease Score Top Affiliating Genes
1 eosinophilic gastroenteritis 29.0 CXCL8 GAST HRH2 IL1B IL1RN S100A8
2 atherosclerosis 28.7 CXCL8 IL1B IL1RN LTA TNF
3 tremor, nystagmus, and duodenal ulcer 12.1
4 duodenal ulcer due to antral g-cell hyperfunction 12.0
5 chronic erosive gastritis 11.1
6 peptic ulcer disease 11.1
7 duodenitis 11.0
8 neuhauser daly magnelli syndrome 11.0
9 xanthinuria, type ii 10.9
10 primary syphilis 10.9 GAST SST
11 bone giant cell sarcoma 10.9 GAST SST
12 nutritional optic neuropathy 10.8 GAST SST
13 tabatznik syndrome 10.8 IL1B TNF
14 sternal cleft 10.8 IL1B TNF
15 pulmonary hypertension 10.8 IL1B TNF
16 gastric cancer risk after h. pylori infection 10.7 IL1B IL1RN
17 oculomotor nerve paralysis 10.7 CXCL8 IL1B
18 common peroneal nerve lesion 10.7 CXCL8 IL1B
19 mental retardation, autosomal recessive 53 10.7 GAST SST
20 milk allergy 10.7 IL1B IL1RN
21 basidiobolomycosis 10.7 CXCL8 TNF
22 bladder calculus 10.7 IL1RN TNF
23 hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 10.6 IL1B TNF
24 adenocarcinoma in situ 10.6 CCK GAST
25 congenital insensitivity to pain with hyperhidrosis 10.6 CXCL8 IL1RN
26 infancy electroclinical syndrome 10.6 CXCL8 IL1B
27 scrotal carcinoma 10.6 HRH2 IL1B TNF
28 walker dyson syndrome 10.5 IL1B IL1RN TNF
29 indolent myeloma 10.5 IL1B IL1RN TNF
30 tarsal tunnel syndrome 10.5 CXCL8 TNF
31 benign neonatal seizures 10.5 IL1B IL1RN TNF
32 keloids 10.5 IL1B IL1RN TNF
33 halal setton wang syndrome 10.5 CXCL8 TNF
34 noma 10.5 IL1B IL1RN TNF
35 osmotic diarrhea 10.5 IL1B IL1RN TNF
36 band keratopathy 10.5 IL1B SST TNF
37 iida kannari syndrome 10.5 IL1B IL1RN TNF
38 perianal hematoma 10.5 CCK GAST SST
39 spondylocostal dysostosis 4 10.5 LTA TNF
40 chancroid 10.5 CXCL8 IL1B
41 type 1 papillary adenoma of the kidney 10.5 LTA TNF
42 amyotrophic lateral sclerosis type 10 10.5 CXCL8 IL1B TNF
43 epulis 10.5 CXCL8 IL1B TNF
44 gastric gastrinoma 10.5 GAST SST
45 acquired thrombocytopenia 10.5 CXCL8 IL1B TNF
46 toxoplasmosis 10.5 LTA TNF
47 leprosy 6 10.5 GAST GRP SST
48 testicular infarct 10.5 CXCL8 IL1B TNF
49 ovarian mucinous adenofibroma 10.5 CXCL8 IL1B TNF
50 myeloid sarcoma 10.5 CXCL8 IL1B TNF

Graphical network of the top 20 diseases related to Duodenal Ulcer:



Diseases related to Duodenal Ulcer

Symptoms & Phenotypes for Duodenal Ulcer

Drugs & Therapeutics for Duodenal Ulcer

Drugs for Duodenal Ulcer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 101)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4,Phase 2,Phase 3 26787-78-0 33613 2171
2
Clarithromycin Approved Phase 4,Phase 2,Phase 3 81103-11-9 84029
3
Metronidazole Approved Phase 4,Phase 2,Phase 3 443-48-1 4173
4
Rabeprazole Approved, Investigational Phase 4,Phase 2,Phase 3 117976-89-3 5029
5
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-78-2 2244
6
Pantoprazole Approved Phase 4,Phase 3,Phase 1 102625-70-7 4679
7
Dexlansoprazole Approved Phase 4,Phase 3 138530-94-6, 103577-45-3 9578005
8
Lansoprazole Approved, Investigational Phase 4,Phase 3 103577-45-3 3883
9
Acetaminophen Approved Phase 4 103-90-2 1983
10
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 73590-58-6 4594
11
Potassium Citrate Approved, Vet_approved Phase 4,Phase 3
12
Esomeprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 161796-78-7, 119141-88-7 4594 9579578
13
Celecoxib Approved, Investigational Phase 4,Phase 3 169590-42-5 2662
14
Loxoprofen Approved Phase 4 68767-14-6, 80382-23-6 3965
15
Ranitidine Approved Phase 4,Phase 3 66357-59-3, 66357-35-5 3001055
16 Antacids Phase 4,Phase 2,Phase 3,Phase 1
17 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3
18 Anti-Infective Agents Phase 4,Phase 2,Phase 3
19 Antiparasitic Agents Phase 4,Phase 2,Phase 3
20 Antiprotozoal Agents Phase 4,Phase 2,Phase 3
21 Anti-Ulcer Agents Phase 4,Phase 2,Phase 3,Phase 1
22 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 2,Phase 3
23 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2,Phase 3
24 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1
25
Proton pump inhibitors Phase 4,Phase 2,Phase 3,Phase 1
26 Analgesics Phase 4,Phase 2,Phase 3,Phase 1
27 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3,Phase 1
28 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Phase 1
29 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 2,Phase 3,Phase 1
30 Antipyretics Phase 4,Phase 2,Phase 3,Phase 1
31 Antirheumatic Agents Phase 4,Phase 2,Phase 3,Phase 1
32 Cyclooxygenase Inhibitors Phase 4,Phase 2,Phase 3,Phase 1
33 Fibrinolytic Agents Phase 4,Phase 2,Phase 3,Phase 1
34 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1
35 Platelet Aggregation Inhibitors Phase 4,Phase 2,Phase 3,Phase 1
36 Antibiotics, Antitubercular Phase 4
37
Bismuth Phase 4,Phase 3 7440-69-9 16682734 105143
38 diuretics Phase 4,Phase 3,Phase 2
39 Expectorants Phase 4,Phase 3
40 Natriuretic Agents Phase 4,Phase 3,Phase 2
41 Respiratory System Agents Phase 4,Phase 3
42 Cyclooxygenase 2 Inhibitors Phase 4,Phase 3
43 Ranitidine bismuth citrate Phase 4,Phase 3
44 Citrate Nutraceutical Phase 4,Phase 3
45
Citric Acid Nutraceutical, Vet_approved Phase 4,Phase 3 77-92-9 311
46
Ticlopidine Approved Phase 3 55142-85-3 5472
47
Ketoprofen Approved, Vet_approved Phase 3 22071-15-4 3825
48
Naproxen Approved, Vet_approved Phase 3,Phase 1 22204-53-1 1302 156391
49
Famotidine Approved Phase 3 76824-35-6 3325
50
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774

Interventional clinical trials:

(show top 50) (show all 112)

id Name Status NCT ID Phase Drugs
1 Concomitant Therapy of H. Pylori Unknown status NCT01922765 Phase 4 amoxicillin, clarithromycin, metronidazole, rabeprazole
2 The Effects of Aspirin and Acetaminophen on the Stomach in Healthy Volunteers Completed NCT00594867 Phase 4 Acetaminophen - 4 grams per day + Placebo;Aspirin - 325 mg per day + Placebo;Acetaminophen 4 gram per day + Aspirin 325 mg per day
3 Relation of Metabolic Rate of Omeprazole and Eradication of Helicobacter Pylori Infection Completed NCT00854451 Phase 4 omeprazole plus amoxicillin;omeprazole plus amoxicillin;omeprazole plus amoxicillin;omeprazole plus amoxicillin
4 Different Dose of Intravenous Omeprazole to Treat Bleeding Ulcer With Adherent Clot Completed NCT02536989 Phase 4 omeprazole;omeprazole
5 Efficacy and Safety of Ilaprazole Based Bismuth-containing Quadruple Regimen for the First-line Treatment of Helicobacter Pylori Infection Completed NCT02835560 Phase 4 Ilaprazole antisecretory drug of each quadruple therapy the Ilaprazole -based quadruple therapy;Esoprazole antisecretory drug of each quadruple therapy Esoprazole-based quadruple therapy
6 A Study of Rabeprazole and Pantoprazole on Stomach Acid and Esophageal Acid Exposure in Patients With Gastroesophageal Reflux Disease (GERD) and a History of Nighttime Heartburn Completed NCT00237367 Phase 4 rabeprazole and pantoprazole
7 Importance of Cytokines in Peptic Ulcer Disease: Implications for Treatment Completed NCT00534443 Phase 4
8 Argon Plasma Coagulation for Bleeding Peptic Ulcers Completed NCT02241044 Phase 4
9 Study Of Celecoxib In Healthy Subjects Completed NCT00994461 Phase 4 Celecoxib;Loxoprofen;Placebo
10 Fast-track Surgery for Perforated Peptic Ulcers Completed NCT01620671 Phase 4
11 Helicobacter Eradication Aspirin Trial Recruiting NCT01506986 Phase 4 Lansoprazole 30mg, Clarithromycin 500mg, Metronidazole 400mg;Placebo lansoprazole 30mg, clarithromycin 500mg, metronidazole 400mg
12 Lansoprazole Preventing Gastroduodenal Stress Ulcerations Terminated NCT00220909 Phase 4 Lansoprazole
13 Effectiveness of the Eradication of Helicobacter Pylori and an Inhibitor of Pump With Proton Versus Control Withdrawn NCT00713947 Phase 4 during one week for the active treatments;Pantoprazole;Placebo Formula 515
14 Second Line Therapy for the Cure of Helicobacter Pylori (H. Pylori) Infection Unknown status NCT00197418 Phase 2, Phase 3 rabeprazole, amoxicillin, clarithromycin, metronidazole
15 Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. Pylori Unknown status NCT00149084 Phase 3 Lansoprazole, clarithromycin, amoxicillin
16 Standardized Fecal Microbiota Transplantation for Ulcerative Colitis Unknown status NCT01790061 Phase 2, Phase 3 Traditional treatments according to associated guidelines
17 Efficacy and Safety of TAK-438 Compared to AG-1749 (Lansoprazole) in the Treatment of Duodenal Ulcer Completed NCT01452724 Phase 3 TAK-438;Placebo;Lansoprazole;Placebo
18 Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study) Completed NCT01397448 Phase 2, Phase 3 E3810;E3810;Teprenone
19 Efficacy and Safety of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin Completed NCT01452763 Phase 3 TAK-438;Placebo;TAK-438;Placebo;Lansoprazole;Placebo
20 Efficacy and Safety of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Non-steroidal Anti-inflammatory Drug (NSAID) Completed NCT01452750 Phase 3 TAK-438;Placebo;TAK-438;Placebo;Lansoprazole;Placebo
21 Long-term Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study) Completed NCT01398410 Phase 2, Phase 3 Rabeprazole;Rabeprazole
22 Efficacy and Safety of Lansoprazole on Gastric and Duodenal Ulcers in Patients Taking Nonsteroidal Anti-Inflammatory Drugs Completed NCT00787254 Phase 3 Lansoprazole;Gefarnate
23 Comparative Efficacy & Safety Study of Esomeprazole Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With NSAID Completed NCT00542789 Phase 3 Esomeprazole;Placebo
24 Ilaprazole for the Treatment of Duodenal Ulcer in Chinese Patients Completed NCT02847455 Phase 2, Phase 3 5 mg ilaprazole;10 mg ilaprazole;10 mg Rabeprazole
25 Ilaprazole for the Treatment of Duodenal Ulcer in Chinese Patients (Phase 3) Completed NCT00952978 Phase 3 10 mg ilaprazole;20 mg omeprazole
26 Comparative Efficacy & Safety Study of D961H Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With Low-dose Aspirin Completed NCT01069939 Phase 3 Esomeprazole;Placebo
27 Long-term Extension Study of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin Completed NCT01456247 Phase 3 TAK-438;Placebo;TAK-438;Placebo;Lansoprazole;Placebo
28 Long-term Extension Study of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Non-steroidal Anti-inflammatory Drug (NSAID) Completed NCT01456260 Phase 3 TAK-438;Placebo;TAK-438;Placebo;Lansoprazole;Placebo
29 A Unblinded Study of TAK-438 (20 mg) for Prevention of Recurrence of Gastric or Duodenal Ulcer During Long-Term Low-Dose Aspirin Therapy Completed NCT01568398 Phase 3 TAK-438
30 A Unblinded Study of TAK-438 (20 mg) for Prevention of Recurrence of Gastric or Duodenal Ulcer During Long-Term Non-Steroid Anti-Inflammatory Drug (NSAID) Therapy Completed NCT01568385 Phase 3 TAK-438
31 Long Term Study to Investigate the Efficacy & Safety of D961H (Esomeprazole) for the Prevention of NSAIDs-induced Ulcer Completed NCT00595517 Phase 3 Esomeprazole 20 mg
32 Cardio-cerebrovascular Disease and Aspirin Ulcer Relapse Evaluation Completed NCT01051388 Phase 3 Low-dose PPI (Rabeprazole sodium);High-dose PPI (Rabeprazole sodium);Non-PPI (Gefarnate)
33 ASTERIX: Low Dose ASA and Nexium Completed NCT00251966 Phase 3 Esomeprazole
34 Study of Esomeprazole 20 mg or 40 mg vs Placebo Effectiveness on the Occurrence of Peptic Ulcers in Subjects on Low Dose Acetylsalicylic Acid (LDA) Completed NCT00441727 Phase 3 Esomeprazole 40 mg;Esomeprazole 20 mg;Placebo
35 Efficacy/Safety Study as H. Pylori Eradication of Triple Therapy for 7 Days Treatment Completed NCT02084420 Phase 3 Ilaprazole;Pantoprazole
36 Ulcer Prevention II Completed NCT00629928 Phase 3 Esomeprazole;Esomeprazole;Placebo
37 A Phase I/III Study of D961H 10 mg and 20 mg in Japanese Paediatric Patients With Gastrointestinal Acid Related Diseases Completed NCT02153398 Phase 3 D961H sachet 10 mg;D961H capsule 10mg;D961H capsule 20 mg
38 Safety, Tolerability and Efficacy Study With a Fixed-Dose Combination (FDC) Ketoprofen Plus Omeprazole Completed NCT00971581 Phase 3 FDC KETOPROFEN+OMEPRAZOLE
39 A Study of Rabeprazole for Prevention of Non Steroidal Anti-inflammatory Drug -Associated Gastroduodenal Injury Completed NCT01140828 Phase 3 Rabeprazole;Rabeprazole Placebo
40 Efficacy of TAK-438, Amoxicillin and Clarithromycin in the First Line Eradication of H. Pylori Completed NCT01505127 Phase 3 TAK-438;Lansoprazole;Amoxicillin;Clarithromycin
41 Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PN 200 or Naproxen in Subjects Who Are at Risk for Developing NSAID-Associated Ulcers. Completed NCT00367211 Phase 3 PN 200 tablets (500 mg naproxen and 20 mg omeprazole);Naproxen 500 mg tablets (PN 200 minus omeprazole)
42 Phase III General Clinical Study of NPO-11 in Patients Undergoing Gastric Endoscopy Completed NCT00745459 Phase 3 NPO-11
43 Efficacy and Safety Study of HZT-501 in Reducing the Risk of Ibuprofen-associated Ulcers Completed NCT00450658 Phase 3 HZT-501;Ibuprofen
44 Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment Completed NCT00450216 Phase 3 Ibuprofen/famotidine;Ibuprofen
45 Helicobacter Pylori Eradication With a New Sequential Treatment Completed NCT00132171 Phase 3 Sequential therapy
46 Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PA32540 or Enteric Coated Aspirin 325 mg in Subjects Who Are at Risk for Developing Aspirin-Associated Ulcers Completed NCT00960869 Phase 3 PA32540;EC-Aspirin 325 mg
47 A Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PA32540 or Enteric Coated Aspirin 325 mg in Subjects Who Are at Risk for Developing Aspirin-Associated Ulcers Completed NCT00961350 Phase 3 PA32540;EC Aspirin 325
48 A Comparison of Safety and Treatment in Subjects With Osteoarthritis Taking Low Dose Aspirin Completed NCT00175032 Phase 3 Lansoprazole and naproxen and aspirin;Celecoxib and aspirin
49 Evaluating PN 400 (VIMOVO) in Reducing Gastric Ulcers Compared to Non-steroidal Antiinflammatory Drug (NSAID) Naproxen Completed NCT01129011 Phase 3 PN400 (VIMOVO);Naproxen
50 Evaluating PN 400 (VIMOVO) in Reducing Gastric Ulcers Compared to Non-steroidal Antiinflammatory Drug (NSAID) Naproxen Completed NCT00527787 Phase 3 PN400 (VIMOVO);Naproxen

Search NIH Clinical Center for Duodenal Ulcer

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: duodenal ulcer

Genetic Tests for Duodenal Ulcer

Anatomical Context for Duodenal Ulcer

MalaCards organs/tissues related to Duodenal Ulcer:

39
Testes, Liver, Colon, Pancreas, Heart, Endothelial, Neutrophil

Publications for Duodenal Ulcer

Articles related to Duodenal Ulcer:

(show top 50) (show all 839)
id Title Authors Year
1
A Rare Case of Pancreas Divisum Accompanied by Acute Pancreatitis Following Endoscopic Hemostasis for Duodenal Ulcer Bleeding. ( 28449428 )
2017
2
The Relationship of Mean Platelet Volume/Platelet Distribution Width and Duodenal Ulcer Perforation. ( 28442518 )
2017
3
Closure of duodenal ulcer perforation using a novel endoloop device with a single-channel gastroscope after failed laparoscopic repair. ( 28068696 )
2017
4
VacA and CagA Status as Biomarker of Two Opposite End Outcomes of Helicobacter pylori Infection (Gastric Cancer and Duodenal Ulcer) in a Moroccan Population. ( 28125638 )
2017
5
Effectiveness of arterial embolization in recurrent bleeding due to duodenal ulcer during postoperative cardiac surgery. ( 28372451 )
2017
6
Perforated Duodenal Ulcer. ( 28248764 )
2017
7
Declining prevalence of duodenal ulcer at endoscopy in Ile-Ife, Nigeria. ( 28875881 )
2017
8
Adapted ERAS Pathway vs. Standard Care in Patients with Perforated Duodenal Ulcer-a Randomized Controlled Trial. ( 28653239 )
2017
9
ExposAc: Different Faces of a Bleeding Giant Duodenal Ulcer. ( 28871345 )
2017
10
Endoscopic View of Gastroduodenal Artery Coils at the Base of Duodenal Ulcer in Case of Recurrent Massive Upper Gastrointestinal Bleed. ( 28507835 )
2017
11
A Curious Case of Intestinal Diaphragm Disease Unmasked by Perforation of a Duodenal Ulcer. ( 28523070 )
2017
12
A case of an intractable duodenal ulcer associated with a pancreatic arteriovenous malformation. ( 28484196 )
2017
13
Successful Endoscopic Treatment of Bouveret Syndrome in a Patient with Choledochoduodenal Fistula Complicating Duodenal Ulcer. ( 28758036 )
2017
14
Protein signature characterizing Helicobacter pylori strains of patients with autoimmune atrophic gastritis, duodenal ulcer and gastric cancer. ( 28465717 )
2017
15
Duodenal Ulcer - IgA Vasculitis. ( 28202872 )
2017
16
Successful Conservative Treatment of a Cholecystoduodenal Fistula Caused by a Cytomegalovirus-associated Duodenal Ulcer. ( 27629956 )
2016
17
Sequential versus concomitant therapy for eradication of Helicobacter Pylori in patients with perforated duodenal ulcer: A randomized trial. ( 27488326 )
2016
18
Peritonitis Following Duodenal Ulcer Perforation in a Newborn: A Case Report. ( 28050434 )
2016
19
A refractory duodenal ulcer with a biliary-duodenal fistula following the administration of bevacizumab. ( 27383109 )
2016
20
Weight loss and decubitus duodenal ulcer in Parkinson's disease treated with levodopa-carbidopa intestinal gel infusion. ( 27614656 )
2016
21
Hypergastrinemia and a duodenal ulcer caused by gastric duplication. ( 27464496 )
2016
22
A Non-invasive 24 Hours Stabilization of Duodenal Ulcer Perforation by a Combination Regimen. ( 28083452 )
2016
23
Modeling the cost-effectiveness of ilaprazole versus omeprazole for the treatment of newly diagnosed duodenal ulcer patients in China. ( 27223846 )
2016
24
Helicobacter pylori Strains from Duodenal Ulcer Patients Exhibit Mixed babA/B Genotypes with Low Levels of BabA Adhesin and Lewis b Binding. ( 27318698 )
2016
25
An Unusual Cause of Duodenal Ulcer Bleeding. ( 27091725 )
2016
26
'Rare' manifestation of 'rare' disease: sarcoidosis presenting as pancreatitis, duodenal ulcer and severe acute kidney injury. ( 27506671 )
2016
27
Duodenal Ulcer Induced by Hem-o-Lok clip after Reduced Port Laparoscopic Cholecystectomy. ( 27014759 )
2016
28
Cytomegalovirus-infected duodenal ulcer with severe recurrent bleeding. ( 26852085 )
2016
29
History of a penetrating duodenal ulcer as a cause of acute necrotizing pancreatitis. ( 27305186 )
2016
30
A Case of Eosinophilic Gastroenteritis Forming a Rigid Chamber Mimicking Giant Duodenal Ulcer on Computed Tomography Imaging. ( 27086704 )
2016
31
Pyopneumothorax and peritonitis due to perforated duodenal ulcer and associated pleuroperitoneal communication. ( 27372035 )
2016
32
Helicobacter pylori and gastric or duodenal ulcer. ( 26942258 )
2016
33
Laparoscopic surgical technique for perforated duodenal ulcer. ( 26972898 )
2016
34
Perforated Duodenal Ulcer. ( 26928104 )
2016
35
Association of Endoscopic Esophageal Variceal Ligation with Duodenal Ulcer. ( 27097695 )
2016
36
The Effect of Helicobacter pylori Eradication on the Gastrointestinal Microbiota in Patients with Duodenal Ulcer. ( 27308643 )
2016
37
Successful Endoscopic Management of Non-Healing Perforated Duodenal Ulcer with Polyglycolic Acid Sheet and Fibrin Glue. ( 28119948 )
2016
38
The Selective Arterial Calcium Injection Test is a Valid Diagnostic Method for Invisible Gastrinoma with Duodenal Ulcer Stenosis: A Case Report. ( 27348901 )
2016
39
Successful treatment of a perforated duodenal ulcer with polyglycolic acid sheets. ( 27492713 )
2016
40
A life-threatening duodenal ulcer hemorrhage due to previously unknown primary hyperparathyroidism. ( 27616071 )
2016
41
PERFORATED DUODENAL ULCER ASSOCIATED WITH SITUS INVERSUS AND DEXTROCARDIA. ( 27323596 )
2016
42
Parameters of proliferation and apoptosis of epithelial cells in the gastric mucosa in indigenous and non-indigenous residents of Khakassia with Helicobacter pylori positive duodenal ulcer disease. ( 25711663 )
2015
43
Perforated duodenal ulcer: An unusual manifestation of allergic eosinophilic gastroenteritis. ( 26640348 )
2015
44
Laparoscopic Surgery for Perforated Duodenal Ulcer Disease: Analysis of 70 Consecutive Cases From a Single Surgeon. ( 25799260 )
2015
45
Thyroid storm precipitated by duodenal ulcer perforation. ( 25838951 )
2015
46
A rare case of duodenal ulcer perforation accompanied by Boerhaave syndrome. ( 26702287 )
2015
47
Duodenal ulcer caused by a surgical clip after laparoscopic cholecystectomy. ( 26099083 )
2015
48
A Technique for Localizing Perforated Duodenal Ulcer During Laparoscopic Repair. ( 27011591 )
2015
49
Polymorphisms in TLR9 but not in TLR5 increase the risk for duodenal ulcer and alter cytokine expression in the gastric mucosa. ( 25995217 )
2015
50
Association of PSCA rs2294008 gene variants with poor prognosis and increased susceptibility to gastric cancer and decreased risk of duodenal ulcer disease. ( 25721731 )
2015

Variations for Duodenal Ulcer

Expression for Duodenal Ulcer

Search GEO for disease gene expression data for Duodenal Ulcer.

Pathways for Duodenal Ulcer

Pathways related to Duodenal Ulcer according to GeneCards Suite gene sharing:

(show all 26)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.66 CXCL8 IL1B INS LTA TNF
2
Show member pathways
12.11 CXCL8 IL1B S100A8 TNF
3 11.87 CXCL8 IL1B TNF
4 11.84 CXCL8 IL1B TNF
5
Show member pathways
11.83 CXCL8 IL1B LTA TNF
6 11.81 IL1B LTA TNF
7 11.79 CXCL8 IL1B INS
8
Show member pathways
11.79 IL1B LTA TNF
9 11.77 CXCL8 IL1B IL1RN SST TNF
10 11.75 CXCL8 IL1B TNF
11 11.73 CXCL8 IL1B TNF
12 11.69 CXCL8 IL1B TNF
13 11.63 IL1B LTA TNF
14 11.59 CXCL8 IL1B TNF
15 11.54 CXCL8 IL1B LTA TNF
16 11.49 CXCL8 IL1B TNF
17
Show member pathways
11.47 CXCL8 IL1B TNF
18 11.37 CXCL8 IL1B TNF
19 11.23 CXCL8 IL1B TNF
20 10.97 IL1B TNF
21 10.95 CXCL8 IL1B IL1RN TNF
22 10.94 CXCL8 IL1B LTA TNF
23 10.9 CXCL8 TNF
24 10.82 IL1B TNF
25 10.13 GAST HRH2
26 9.77 CCK GAST GRP SCT

GO Terms for Duodenal Ulcer

Cellular components related to Duodenal Ulcer according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.73 CCK CXCL8 GAST GRP IL1B IL1RN
2 extracellular space GO:0005615 9.4 CCK CXCL8 GAST GRP IL1B IL1RN
3 secretory granule lumen GO:0034774 9.33 GRP INS S100A8

Biological processes related to Duodenal Ulcer according to GeneCards Suite gene sharing:

(show all 26)
id Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.89 IL1B INS LTA SST
2 inflammatory response GO:0006954 9.8 CXCL8 IL1B IL1RN S100A8 TNF
3 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.74 CCK S100A8 TNF
4 neutrophil chemotaxis GO:0030593 9.72 CXCL8 IL1B S100A8
5 positive regulation of nitric oxide biosynthetic process GO:0045429 9.63 IL1B INS TNF
6 immune response GO:0006955 9.63 CXCL8 HRH2 IL1B IL1RN LTA TNF
7 positive regulation of NF-kappaB import into nucleus GO:0042346 9.62 IL1B TNF
8 regulation of protein secretion GO:0050708 9.62 INS TNF
9 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.62 IL1B INS S100A8 TNF
10 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.61 IL1B TNF
11 negative regulation of growth of symbiont in host GO:0044130 9.61 LTA TNF
12 positive regulation of interferon-gamma production GO:0032729 9.61 IL1B LTA TNF
13 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.6 IL1B TNF
14 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.58 IL1B TNF
15 positive regulation of chemokine biosynthetic process GO:0045080 9.58 IL1B TNF
16 positive regulation of peptide hormone secretion GO:0090277 9.56 GRP INS
17 regulation of establishment of endothelial barrier GO:1903140 9.54 IL1B TNF
18 positive regulation of fever generation GO:0031622 9.51 IL1B TNF
19 sequestering of triglyceride GO:0030730 9.49 IL1B TNF
20 positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 9.48 LTA TNF
21 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.37 IL1B TNF
22 positive regulation of chronic inflammatory response to antigenic stimulus GO:0002876 9.26 LTA TNF
23 fever generation GO:0001660 9.22 IL1B
24 embryonic digestive tract development GO:0048566 9.13 CXCL8 SCT TNF
25 negative regulation of lipid catabolic process GO:0050995 8.8 IL1B INS TNF
26 signal transduction GO:0007165 10.17 CCK CXCL8 GAST GRP HRH2 IL1B

Molecular functions related to Duodenal Ulcer according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.35 CXCL8 IL1B IL1RN LTA TNF
2 interleukin-1 receptor binding GO:0005149 9.16 IL1B IL1RN
3 hormone activity GO:0005179 9.02 CCK GAST INS SCT SST

Sources for Duodenal Ulcer

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